M S-medecine SciencesPub Date : 2025-01-01Epub Date: 2025-01-31DOI: 10.1051/medsci/2024203
Àna-Sofia Eria-Oliveira, Michel Vivaudou
{"title":"[Photocontrol of intracellular calcium concentration by a virus-encoded rhodopsin: Application to the light-induced restoration of movement in paralyzed animals].","authors":"Àna-Sofia Eria-Oliveira, Michel Vivaudou","doi":"10.1051/medsci/2024203","DOIUrl":"https://doi.org/10.1051/medsci/2024203","url":null,"abstract":"","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"41 1","pages":"23-25"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143066745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Reporting the overall results of the research to the participants: issues, barriers and areas for improvement].","authors":"Fanny Momboisse, Julie Fournié, Bénédicte Richard, Rémy Artus","doi":"10.1051/medsci/2024189","DOIUrl":"10.1051/medsci/2024189","url":null,"abstract":"<p><p>The overall results of a research project represent a synthesis of the individual results obtained from the participants, which together lead to the conclusions of the research. The importance of informing participants is emphasised in the recommendations on research ethics. However, this good practice is not systematic and can present various challenges in its implementation, despite the fact that participants often express a desire to be informed. The potential advantages and disadvantages of this method raise questions for researchers, who have the task of conveying a coherent message to all parties, while at the same time addressing the lack of guidance on this practice. Potential avenues for improvement include expending the body of ethics literature on the subject and developing comprehensive guidelines to provide optimal support for research teams using this practice.</p>","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"41 1","pages":"63-67"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143066750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M S-medecine SciencesPub Date : 2025-01-01Epub Date: 2025-01-31DOI: 10.1051/medsci/2024192
Solène Roux, Nofel Merbahi, Michel Simon
{"title":"[Atmospheric pressure cold plasma-activated media, a new therapeutic approach for skin wound healing and beyond?]","authors":"Solène Roux, Nofel Merbahi, Michel Simon","doi":"10.1051/medsci/2024192","DOIUrl":"10.1051/medsci/2024192","url":null,"abstract":"<p><p>The direct application of cold plasmas at atmospheric pressure, corresponding to partially ionized gases, is an emerging technology with a number of potential biomedical applications, including the decontamination of surgical devices. A new derived and easier to implement method has recently been developed: the use of cold atmospheric plasma-activated media (PAM). Numerous preclinical studies and in vitro models indicates that PAM treatments facilitate wound healing by promoting keratinocytes and fibroblasts migration, stimulating angiogenesis, and inhibiting bacterial proliferation, all of which are essential for this vital process. PAM treatments induce the expression of cytokines, growth factors and matrix metalloproteinases, reduce cellular adhesion, and promote cytoskeletal changes, probably under the influence of plasma-generated reactive oxygen and nitrogen species. PAM treatments represent a promising novel therapy for treating chronic skin and mucosal wounds.</p>","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"41 1","pages":"40-46"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143066726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M S-medecine SciencesPub Date : 2025-01-01Epub Date: 2025-01-31DOI: 10.1051/medsci/2024188
Bertrand Jordan
{"title":"[The fall of an Unicom].","authors":"Bertrand Jordan","doi":"10.1051/medsci/2024188","DOIUrl":"10.1051/medsci/2024188","url":null,"abstract":"<p><p>23andMe, a company pioneering on-demand genetic profiling, has attracted much attention, millions of customers and very significant investments, as well as some lucrative collaborations with the pharmaceutical industry. Yet the company is now in deep trouble, with shares worth pennies, and may go bankrupt in the near future. This article describes the firm's history and attempts to understand its problems.</p>","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"41 1","pages":"73-76"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143066757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M S-medecine SciencesPub Date : 2025-01-01Epub Date: 2025-01-31DOI: 10.1051/medsci/2024193
Didier Casane, Maude W Baldwin, Walter Salzburger, Maxime Policarpo
{"title":"[Massive gene losses: the case of chemoreceptors in aquatic tetrapods].","authors":"Didier Casane, Maude W Baldwin, Walter Salzburger, Maxime Policarpo","doi":"10.1051/medsci/2024193","DOIUrl":"10.1051/medsci/2024193","url":null,"abstract":"<p><p>The existence of multigene families is the result of gene duplication. In vertebrates, the genes coding for the chemoreceptors involved in olfaction often form large families, sometimes comprising several thousand genes. In this case, it is assumed that a large number of genes is essential to discriminate between a large number of odorant molecules, and that the ability to identify a large number of odors may be necessary for different purposes, such as finding food and sexual partners, and avoiding predators. However, it has been found that in some species the number of these genes is very small, resulting from the secondary loss of many genes. This massive loss of genes is not always clearly associated with a change in the biology of the species or its environment, but in some cases, it is associated with drastic changes, such as the return to aquatic life in tetrapods.</p>","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"41 1","pages":"47-52"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143066740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M S-medecine SciencesPub Date : 2025-01-01Epub Date: 2025-01-31DOI: 10.1051/medsci/2024185
Cristina Gonzalez Prieto, Marie Malier, Arnaud Millet
{"title":"[Control of tumor-associated macrophage metabolism by the CSF1R pathway: an opportunity to restore chemosensitivity to 5-Fluorouracil in colorectal cancers?]","authors":"Cristina Gonzalez Prieto, Marie Malier, Arnaud Millet","doi":"10.1051/medsci/2024185","DOIUrl":"https://doi.org/10.1051/medsci/2024185","url":null,"abstract":"","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"41 1","pages":"16-18"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143066727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Paleopathological analysis of prenatal and postnatal vitamin D deficiency using teeth as tool].","authors":"Ysabel-Marion Delbos, Marie-Amélie Deminière, Sarah Girard, Léa Zaragoza, Caroline Costedoat, Émeline Verna","doi":"10.1051/medsci/2024199","DOIUrl":"https://doi.org/10.1051/medsci/2024199","url":null,"abstract":"","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"41 1","pages":"90-92"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143066743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M S-medecine SciencesPub Date : 2025-01-01Epub Date: 2025-01-31DOI: 10.1051/medsci/2024187
Benjamin Davido, Djillali Annane
{"title":"[Correction of eosinopenia during respiratory infections is a predictor of oxygen weaning].","authors":"Benjamin Davido, Djillali Annane","doi":"10.1051/medsci/2024187","DOIUrl":"https://doi.org/10.1051/medsci/2024187","url":null,"abstract":"","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"41 1","pages":"9-12"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143066728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}