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[Towards in vivo production of CAR-T cells: an announced revolution?] CAR-T细胞的体内生产：一场宣布的革命？］
IF 0.4 4区 医学
M S-medecine Sciences Pub Date : 2026-04-01 Epub Date: 2026-04-24 DOI: 10.1051/medsci/2026053
Emmanuel Donnadieu
{"title":"[Towards in vivo production of CAR-T cells: an announced revolution?]","authors":"Emmanuel Donnadieu","doi":"10.1051/medsci/2026053","DOIUrl":"https://doi.org/10.1051/medsci/2026053","url":null,"abstract":"","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"42 4","pages":"352-353"},"PeriodicalIF":0.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147775824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[TimeVaults provide recordings of past cellular activity]. [时间库提供过去手机活动的记录]。
IF 0.5 4区 医学
M S-medecine Sciences Pub Date : 2026-04-01 Epub Date: 2026-04-24 DOI: 10.1051/medsci/2026061
Bertrand Jordan
{"title":"[TimeVaults provide recordings of past cellular activity].","authors":"Bertrand Jordan","doi":"10.1051/medsci/2026061","DOIUrl":"10.1051/medsci/2026061","url":null,"abstract":"<p><p>Inventive engineering of cellular organelles (Vaults) allows durable recording and later readout of the cellular transcriptional activity of living cells, at a given time point, opening up a large series of applications.</p>","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"42 4","pages":"393-395"},"PeriodicalIF":0.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147775753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Atypical antiviral gene discovered in a mosquito]. [在蚊子中发现的非典型抗病毒基因]。
IF 0.4 4区 医学
M S-medecine Sciences Pub Date : 2026-04-01 Epub Date: 2026-04-24 DOI: 10.1051/medsci/2026050
Louis Lambrechts
{"title":"[Atypical antiviral gene discovered in a mosquito].","authors":"Louis Lambrechts","doi":"10.1051/medsci/2026050","DOIUrl":"https://doi.org/10.1051/medsci/2026050","url":null,"abstract":"","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"42 4","pages":"344-345"},"PeriodicalIF":0.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147775591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Protein aggregation: from the prion exception to a general paradigm of neurodegeneration]. [蛋白质聚集：从朊病毒例外到神经变性的一般范例]。
IF 0.4 4区 医学
M S-medecine Sciences Pub Date : 2026-04-01 Epub Date: 2026-04-24 DOI: 10.1051/medsci/2026064
Vincent Beringue
{"title":"[Protein aggregation: from the prion exception to a general paradigm of neurodegeneration].","authors":"Vincent Beringue","doi":"10.1051/medsci/2026064","DOIUrl":"https://doi.org/10.1051/medsci/2026064","url":null,"abstract":"","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"42 4","pages":"323-324"},"PeriodicalIF":0.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147775605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Cutaneous pre- and probiotics: Modulating the axillary microbiome to control body odors]. [皮肤预益生菌和益生菌：调节腋窝微生物群以控制体味]。
IF 0.5 4区 医学
M S-medecine Sciences Pub Date : 2026-04-01 Epub Date: 2026-04-24 DOI: 10.1051/medsci/2026062
Gwendoline Joncour, Sam Saghbini
{"title":"[Cutaneous pre- and probiotics: Modulating the axillary microbiome to control body odors].","authors":"Gwendoline Joncour, Sam Saghbini","doi":"10.1051/medsci/2026062","DOIUrl":"10.1051/medsci/2026062","url":null,"abstract":"","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"42 4","pages":"398-401"},"PeriodicalIF":0.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147775652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Characterization of human papillomavirus genomes integrated into the cellular genome: roles in oncogenesis and clinical applications]. [整合到细胞基因组中的人乳头瘤病毒基因组的特征：在肿瘤发生和临床应用中的作用]。
IF 0.5 4区 医学
M S-medecine Sciences Pub Date : 2026-04-01 Epub Date: 2026-04-24 DOI: 10.1051/medsci/2026055
Xavier Sastre-Garau, Abir Al Ghuzlan, Rana Mitri-Frangieh
{"title":"[Characterization of human papillomavirus genomes integrated into the cellular genome: roles in oncogenesis and clinical applications].","authors":"Xavier Sastre-Garau, Abir Al Ghuzlan, Rana Mitri-Frangieh","doi":"10.1051/medsci/2026055","DOIUrl":"10.1051/medsci/2026055","url":null,"abstract":"<p><p>Most invasive carcinoma associated with HPV harbor viral sequences integrated into the cellular genome. Sequencing approaches, which enable in-depth characterization of viral sequences, show that in 80 % of cases, viral insertion targets a gene whose expression level is frequently altered. Approximately one third of these genes correspond to potential therapeutic targets. The application of sequencing approaches to the analysis of circulating viral DNA has allowed the development of validated clinical applications in the fields of diagnosis and follow-up. These advances should also benefit to the development of innovative therapies targeting viral sequences.</p>","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"42 4","pages":"365-372"},"PeriodicalIF":0.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147775604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Near-term prevention of sudden cardiac death: Artificial intelligence applied to ambulatory ECGs]. [近期预防心源性猝死：人工智能在动态心电图中的应用]。
IF 0.4 4区 医学
M S-medecine Sciences Pub Date : 2026-04-01 Epub Date: 2026-04-24 DOI: 10.1051/medsci/2026052
Laurent Fiorina, Eloi Marijon
{"title":"[Near-term prevention of sudden cardiac death: Artificial intelligence applied to ambulatory ECGs].","authors":"Laurent Fiorina, Eloi Marijon","doi":"10.1051/medsci/2026052","DOIUrl":"https://doi.org/10.1051/medsci/2026052","url":null,"abstract":"","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"42 4","pages":"350-351"},"PeriodicalIF":0.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147775576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Maternal obesity and hepatic steatosis in the offspring: macrophages are guilty]. [母体肥胖和后代肝脂肪变性：巨噬细胞是罪魁祸首]。
IF 0.4 4区 医学
M S-medecine Sciences Pub Date : 2026-04-01 Epub Date: 2026-04-24 DOI: 10.1051/medsci/2026045
Hélène Gilgenkrantz
{"title":"[Maternal obesity and hepatic steatosis in the offspring: macrophages are guilty].","authors":"Hélène Gilgenkrantz","doi":"10.1051/medsci/2026045","DOIUrl":"https://doi.org/10.1051/medsci/2026045","url":null,"abstract":"","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"42 4","pages":"328-330"},"PeriodicalIF":0.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147775586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The radio-induced antitumor immune response as a therapeutic target]. [放射诱导的抗肿瘤免疫反应作为治疗靶点]。
IF 0.4 4区 医学
M S-medecine Sciences Pub Date : 2026-04-01 Epub Date: 2026-04-24 DOI: 10.1051/medsci/2026047
Valentin Monteiro, Michèle Mondini, Eric Deutsch, Germain Rousselet
{"title":"[The radio-induced antitumor immune response as a therapeutic target].","authors":"Valentin Monteiro, Michèle Mondini, Eric Deutsch, Germain Rousselet","doi":"10.1051/medsci/2026047","DOIUrl":"https://doi.org/10.1051/medsci/2026047","url":null,"abstract":"","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"42 4","pages":"334-336"},"PeriodicalIF":0.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147775746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[When social inequalities get under the skin]. （当社会不平等深入人心时）。
IF 0.4 4区 医学
M S-medecine Sciences Pub Date : 2026-04-01 Epub Date: 2026-04-24 DOI: 10.1051/medsci/2026060
Anne-Marie Moulin
{"title":"[When social inequalities get under the skin].","authors":"Anne-Marie Moulin","doi":"10.1051/medsci/2026060","DOIUrl":"https://doi.org/10.1051/medsci/2026060","url":null,"abstract":"","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"42 4","pages":"390-391"},"PeriodicalIF":0.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147775768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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