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[Control of tumor-associated macrophage metabolism by the CSF1R pathway: an opportunity to restore chemosensitivity to 5-Fluorouracil in colorectal cancers?] 通过CSF1R途径控制肿瘤相关巨噬细胞代谢：恢复结直肠癌患者对5-氟尿嘧啶化疗敏感性的机会？］
IF 0.6 4区 医学
M S-medecine Sciences Pub Date : 2025-01-01 Epub Date: 2025-01-31 DOI: 10.1051/medsci/2024185
Cristina Gonzalez Prieto, Marie Malier, Arnaud Millet
{"title":"[Control of tumor-associated macrophage metabolism by the CSF1R pathway: an opportunity to restore chemosensitivity to 5-Fluorouracil in colorectal cancers?]","authors":"Cristina Gonzalez Prieto, Marie Malier, Arnaud Millet","doi":"10.1051/medsci/2024185","DOIUrl":"https://doi.org/10.1051/medsci/2024185","url":null,"abstract":"","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"41 1","pages":"16-18"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143066727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Paleopathological analysis of prenatal and postnatal vitamin D deficiency using teeth as tool]. [以牙齿为工具的产前和产后维生素D缺乏症古病理学分析]。
IF 0.6 4区 医学
M S-medecine Sciences Pub Date : 2025-01-01 Epub Date: 2025-01-31 DOI: 10.1051/medsci/2024199
Ysabel-Marion Delbos, Marie-Amélie Deminière, Sarah Girard, Léa Zaragoza, Caroline Costedoat, Émeline Verna
{"title":"[Paleopathological analysis of prenatal and postnatal vitamin D deficiency using teeth as tool].","authors":"Ysabel-Marion Delbos, Marie-Amélie Deminière, Sarah Girard, Léa Zaragoza, Caroline Costedoat, Émeline Verna","doi":"10.1051/medsci/2024199","DOIUrl":"https://doi.org/10.1051/medsci/2024199","url":null,"abstract":"","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"41 1","pages":"90-92"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143066743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Correction of eosinopenia during respiratory infections is a predictor of oxygen weaning]. [在呼吸道感染期间纠正嗜酸性粒细胞减少是一个预测氧脱机的指标]。
IF 0.6 4区 医学
M S-medecine Sciences Pub Date : 2025-01-01 Epub Date: 2025-01-31 DOI: 10.1051/medsci/2024187
Benjamin Davido, Djillali Annane
{"title":"[Correction of eosinopenia during respiratory infections is a predictor of oxygen weaning].","authors":"Benjamin Davido, Djillali Annane","doi":"10.1051/medsci/2024187","DOIUrl":"https://doi.org/10.1051/medsci/2024187","url":null,"abstract":"","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"41 1","pages":"9-12"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143066728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Keep cool! How to inhibit post-mortem production of endogenous GHB?] (保持冷静!如何抑制死后内源性GHB的产生？］
IF 0.6 4区 医学
M S-medecine Sciences Pub Date : 2025-01-01 Epub Date: 2025-01-31 DOI: 10.1051/medsci/2024196
Sarah Hadhoum, Élisa Baranger, Mathilde Ausseil, Maëva Kahn, Caroline Costedoat, Émeline Verna
{"title":"[Keep cool! How to inhibit post-mortem production of endogenous GHB?]","authors":"Sarah Hadhoum, Élisa Baranger, Mathilde Ausseil, Maëva Kahn, Caroline Costedoat, Émeline Verna","doi":"10.1051/medsci/2024196","DOIUrl":"10.1051/medsci/2024196","url":null,"abstract":"","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"41 1","pages":"79-82"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143066738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Innovative technique: 3D printing that gives voice]. 【创新技术：3D打印发声】。
IF 0.6 4区 医学
M S-medecine Sciences Pub Date : 2025-01-01 Epub Date: 2025-01-31 DOI: 10.1051/medsci/2024201
Axel Allache, Angélique Gougeon, Marek Levray, Lucie Poveda, Caroline Costedoat, Émeline Verna
{"title":"[Innovative technique: 3D printing that gives voice].","authors":"Axel Allache, Angélique Gougeon, Marek Levray, Lucie Poveda, Caroline Costedoat, Émeline Verna","doi":"10.1051/medsci/2024201","DOIUrl":"https://doi.org/10.1051/medsci/2024201","url":null,"abstract":"","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"41 1","pages":"97-99"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143066736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Promises and excesses of the "epigenetic era"]. [“表观遗传时代”的承诺和过度行为]。
IF 0.6 4区 医学
M S-medecine Sciences Pub Date : 2024-12-01 Epub Date: 2024-12-20 DOI: 10.1051/medsci/2024194
Vincent Colot
{"title":"[Promises and excesses of the \"epigenetic era\"].","authors":"Vincent Colot","doi":"10.1051/medsci/2024194","DOIUrl":"https://doi.org/10.1051/medsci/2024194","url":null,"abstract":"","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"40 12","pages":"881-882"},"PeriodicalIF":0.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142869310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Protein arginine methyltransferase PRMT2 is involved in the control of inflammation in acute myeloid leukemia]. [蛋白精氨酸甲基转移酶PRMT2参与急性髓性白血病炎症的控制]。
IF 0.6 4区 医学
M S-medecine Sciences Pub Date : 2024-12-01 Epub Date: 2024-12-20 DOI: 10.1051/medsci/2024168
Camille Sauter, Jean-Noël Bastie, Laurent Delva, Romain Aucagne
{"title":"[Protein arginine methyltransferase PRMT2 is involved in the control of inflammation in acute myeloid leukemia].","authors":"Camille Sauter, Jean-Noël Bastie, Laurent Delva, Romain Aucagne","doi":"10.1051/medsci/2024168","DOIUrl":"https://doi.org/10.1051/medsci/2024168","url":null,"abstract":"","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"40 12","pages":"979-982"},"PeriodicalIF":0.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142869312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Targeted epigenome engineering]. [目标表观基因组工程]。
IF 0.6 4区 医学
M S-medecine Sciences Pub Date : 2024-12-01 Epub Date: 2024-12-20 DOI: 10.1051/medsci/2024182
Hedvika Martin, Michel Wassef
{"title":"[Targeted epigenome engineering].","authors":"Hedvika Martin, Michel Wassef","doi":"10.1051/medsci/2024182","DOIUrl":"https://doi.org/10.1051/medsci/2024182","url":null,"abstract":"<p><p>Cellular differentiation and homeostasis rely on complex mechanisms to control gene expression, enabling the different cell lineages of an organism to establish and then \"memorize\" different epigenetic states. The processes that control gene expression are centered on chromatin, a complex of DNA, histone proteins and RNA, whose structure is finely regulated. Targeted epigenomic engineering tools make it possible to interfere with and study these processes, revealing the logic of epigenetic memory mechanisms. This article reviews the main classes of targeted epigenome modification tools and illustrates how they can be used to better understand and modify the epigenome of cells, paving the way for potentially revolutionary therapeutic prospects.</p>","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"40 12","pages":"955-962"},"PeriodicalIF":0.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142869319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Epigenetic reprogramming, germline and genomic imprinting]. [表观遗传重编程，种系和基因组印记]。
IF 0.6 4区 医学
M S-medecine Sciences Pub Date : 2024-12-01 Epub Date: 2024-12-20 DOI: 10.1051/medsci/2024177
Clara Roidor, Karim Chebli, Maud Borensztein
{"title":"[Epigenetic reprogramming, germline and genomic imprinting].","authors":"Clara Roidor, Karim Chebli, Maud Borensztein","doi":"10.1051/medsci/2024177","DOIUrl":"https://doi.org/10.1051/medsci/2024177","url":null,"abstract":"<p><p>The memory of cellular identity is crucial for the correct development of an individual and is maintained throughout life by the epigenome. Chromatin marks, such as DNA methylation and histone modifications, ensure the stability of gene expression programmes over time and through cell division. Loss of these marks can lead to severe pathologies, including cancer and developmental syndromes. However, reprogramming of cellular identity is also a natural phenomenon that occurs early in mammalian development, particularly in the germ line, which enables the production of mature and functional gametes. The germ line transmits genetic and epigenetic information to the next generation, contributing to the survival of the species. Primordial germ cells (PGCs) undergo extensive chromatin remodelling, including global DNA demethylation and erasure of the parental imprints. This review introduces the concept of epigenetic reprogramming, its discovery and key steps, as well as the transcriptional and chromatin changes that accompany germ cell formation in mice. Finally, we discuss the epigenetic mechanisms of genomic imprinting, its discovery, regulation and relevance to human disease.</p>","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"40 12","pages":"892-903"},"PeriodicalIF":0.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142869441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The Lyonisation, a "perfume of women"…]. [里昂化，“女人的香水”…]。
IF 0.6 4区 医学
M S-medecine Sciences Pub Date : 2024-12-01 Epub Date: 2024-12-20 DOI: 10.1051/medsci/2024183
Hélène Gilgenkrantz
{"title":"[The Lyonisation, a \"perfume of women\"…].","authors":"Hélène Gilgenkrantz","doi":"10.1051/medsci/2024183","DOIUrl":"https://doi.org/10.1051/medsci/2024183","url":null,"abstract":"","PeriodicalId":18205,"journal":{"name":"M S-medecine Sciences","volume":"40 12","pages":"963-964"},"PeriodicalIF":0.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142869321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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