[From the emergence of mpox in the Democratic Republic of the Congo to global health emergencies].

IF 0.4 4区 医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL
M S-medecine Sciences Pub Date : 2025-08-01 Epub Date: 2025-09-08 DOI:10.1051/medsci/2025106
Eddy Kinganda-Lusamaki, Ahidjo Ayouba, Placide Mbala-Kingebeni, Steve Ahuka-Mundeke, Jean-Jacques Muyembe-Tamfum, Eric Delaporte, Martine Peeters
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引用次数: 0

Abstract

For a long time neglected, the mpox virus has caused two public health emergency declarations by the World Health Organization in just two years. Rapid detection and characterization of the viral strains involved are crucial for better control of the disease. Recent work on viral genome sequencing in the Democratic Republic of the Congo (DRC) has shown the emergence in 2023 of clade Ib, with sustained human-to-human transmission and rapid spread to several other non-endemic neighboring countries, as well as outside Africa. On the other hand, variants of clade Ia, which is predominant in the DRC and associated with zoonotic transmission, are beginning to emerge in large urban areas such as Kinshasa. The observed adaptation to humans raises concerns about the exportation and globalization of the epidemic.

[从刚果民主共和国出现麻疹到全球突发卫生事件]。
在被长期忽视的情况下,世界卫生组织在短短两年内两次宣布麻疹病毒为公共卫生紧急状态。快速检测和鉴定所涉及的病毒株对于更好地控制该病至关重要。最近在刚果民主共和国开展的病毒基因组测序工作表明,2023年出现了Ib进化支,持续人际传播,并迅速蔓延到其他几个非流行邻国以及非洲以外。另一方面,在刚果民主共和国占主导地位并与人畜共患疾病传播有关的Ia支变体开始在金沙萨等大城市地区出现。观察到的对人类的适应引起了对该流行病输出和全球化的关注。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
M S-medecine Sciences
M S-medecine Sciences 医学-医学:研究与实验
CiteScore
0.80
自引率
14.30%
发文量
182
审稿时长
4-8 weeks
期刊介绍: m/s offers high-quality review articles in French, covering all areas of biomedical and health research, in a monthly magazine format (10 issues / year). m/s is read by the whole French-speaking community, in France but also in Belgium, Switzerland, Canada, Morocco, Algeria, Tunisia etc. m/s is not a primary publication, and thus will not consider unpublished data. Most articles are invited by the Editors, but spontaneous proposals are welcomed. Each issue combines news and views on the most recent scientific publications, as well as broadly accessible and updated review articles on a specific topic, and essays on science and society, history of science, public health, or reactions to published articles. Each year, m/s also publishes one or two thematic issues focused on a research topic of high interest. All review articles and essays are peer-reviewed.
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