Magnetic resonance imaging最新文献

{"title":"A multi-task generative model for simultaneous post-contrast MR image synthesis and brainstem glioma segmentation","authors":"Yajing Zhang ,&nbsp;Yanxin Huang ,&nbsp;Xiangyu Xiong ,&nbsp;Yaou Liu ,&nbsp;Jin Qi","doi":"10.1016/j.mri.2024.07.009","DOIUrl":"10.1016/j.mri.2024.07.009","url":null,"abstract":"<div><h3>Objectives</h3><p>This study aims to generate post-contrast MR images reducing the exposure of gadolinium-based contrast agents (GBCAs) for brainstem glioma (BSG) detection, simultaneously delineating the BSG lesion, and providing high-resolution contrast information.</p></div><div><h3>Methods</h3><p>A retrospective cohort of 30 patients diagnosed with brainstem glioma was included. Multi-contrast images, including pre-contrast T1 weighted (pre-T1w), T2 weighted (T2w), arterial spin labeling (ASL) and post-contrast T1w images, were collected. A multi-task generative model was developed to synthesize post-contrast T1w images and simultaneously segment BSG masks from the multi-contrast inputs. Performance evaluation was conducted using peak signal-to-noise ratio (PSNR), structural similarity index (SSIM), and mean absolute error (MAE) metrics. A perceptual study was also undertaken to assess diagnostic quality.</p></div><div><h3>Results</h3><p>The proposed model achieved SSIM of 0.86 ± 0.04, PSNR of 26.33 ± 0.05 and MAE of 57.20 ± 20.50 for post-contrast T1w image synthesis. Automated delineation of the BSG lesions achieved Dice similarity coefficient (DSC) score of 0.88 ± 0.27.</p></div><div><h3>Conclusions</h3><p>The proposed model can synthesize high-quality post-contrast T1w images and accurately segment the BSG region, yielding satisfactory DSC scores.</p></div><div><h3>Clinical relevance statement</h3><p>The synthesized post-contrast MR image presented in this study has the potential to reduce the usage of gadolinium-based contrast agents, which may pose risks to patients. Moreover, the automated segmentation method proposed in this paper aids radiologists in accurately identifying the brainstem glioma lesion, facilitating the diagnostic process.</p></div>","PeriodicalId":18165,"journal":{"name":"Magnetic resonance imaging","volume":"113 ","pages":"Article 110210"},"PeriodicalIF":2.1,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141734607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dynamic contrast-enhanced and diffusion-weighted MRI of cervical carcinoma: Correlations with Ki-67 proliferation status","authors":"Bingjia Lai ,&nbsp;Yongju Yi ,&nbsp;Xiaojun Yang ,&nbsp;Xiumei Li ,&nbsp;Longjiahui Xu ,&nbsp;Zhuoheng Yan ,&nbsp;Lu Yang ,&nbsp;Riyu Han ,&nbsp;Huijun Hu ,&nbsp;Xiaohui Duan","doi":"10.1016/j.mri.2024.07.010","DOIUrl":"10.1016/j.mri.2024.07.010","url":null,"abstract":"<div><h3>Objectives</h3><p>To investigate the association of quantitative parameter (apparent diffusion coefficient [ADC]) from diffusion-weighted imaging (DWI) and various quantitative and semiquantitative parameters from dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) with Ki-67 proliferation index (PI) in cervical carcinoma (CC).</p></div><div><h3>Methods</h3><p>A total of 102 individuals with CC who received 3.0 T MRI examination (DWI and DCE MRI) between October 2016 and December 2022 were enrolled in our investigation. Two radiologists separately assessed the ADC parameter and various quantitative and semiquantitative parameters including (volume transfer constant [<em>K</em>^{<em>trans</em>}], rate constant [<em>k</em>_ep], extravascular extracellular space volume fraction [<em>v</em>_<em>e</em>], volume fraction of plasma [<em>v</em>_<em>p</em>], time to peak [TTP], maximum concentration [MaxCon], maximal slope [MaxSlope] and area under curve [AUC]) for each tumor. Their association with Ki-67 PI was analyzed by Spearman association analysis. The discrepancy between low-proliferation and high-proliferation groups was subsequently analyzed. The receiver operating characteristic (ROC) curve analysis utilized to identify optimal cut-off points for significant parameters.</p></div><div><h3>Results</h3><p>Both ADC (ρ = −<!--> <!-->0.457, <em>p</em> &lt; 0.001) and <em>K</em>^trans (ρ = −<!--> <!-->0.467, <em>p</em> &lt; 0.001) indicated a strong negative association with Ki-67 PI. Ki-67 PI showed positive correlations with TTP, MaxCon, MaxSlope and AUC (ρ = 0.202, 0.231, 0.309, 0.235, respectively; all <em>p</em> values&lt;0.05). Compared with the low-proliferation group, high-Ki-67 group presented a significantly lower ADC (0.869 ± 0.125 × 10⁻³ mm²/s vs. 1.149 ± 0.318 × 10⁻³ mm²/s; <em>p</em> &lt; 0.001) and <em>K</em>^trans (1.314 ± 1.162 min⁻¹vs. 0.391 ± 0.390 min⁻¹; <em>p</em> &lt; 0.001), also significantly higher MaxCon values (0.756 ± 0.959 vs. 0.422 ± 0.341; <em>p</em> &lt; 0.05) and AUC values (2.373 ± 3.012 vs. 1.273 ± 1.000; <em>p</em> &lt; 0.05). The cut-offs of ADC, <em>K</em>^{<em>trans</em>}, MaxCon and AUC for discrimating low- and high-Ki-67 groups were 0.920 × 10⁻³ mm²/s, 0.304 min⁻¹, 0.209 and 1.918, respectively.</p></div><div><h3>Conclusions</h3><p>ADC, <em>K</em>^trans, TTP, MaxCon, MaxSlope and AUC are associated with Ki-67 PI. ADC and <em>K</em>^trans exhibited high performance to discriminate low and high Ki-67 status of CC.</p></div>","PeriodicalId":18165,"journal":{"name":"Magnetic resonance imaging","volume":"112 ","pages":"Pages 136-143"},"PeriodicalIF":2.1,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141727391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improvement of image quality for bright-blood image in VISIBLE (volume isotropic simultaneous interleaved bright- and black-blood examination) by using k-space reordering and startup echoes","authors":"Tatsuhiro Wada ,&nbsp;Kazufumi Kikuchi ,&nbsp;Makoto Obara ,&nbsp;Chiaki Tokunaga ,&nbsp;Koji Yamashita ,&nbsp;Koji Kobayashi ,&nbsp;Toyoyuki Kato ,&nbsp;Kousei Ishigami ,&nbsp;Osamu Togao","doi":"10.1016/j.mri.2024.07.011","DOIUrl":"10.1016/j.mri.2024.07.011","url":null,"abstract":"<div><h3>Purpose</h3><p>A volume isotropic simultaneous interleaved bright- and black-blood examination (VISIBLE) can simultaneously acquire images with suppressed vascular signals (black-blood images) and images without suppression (bright-blood images). We aimed to improve of the bright-blood images by adjusting the k-space filling and using startup echo.</p></div><div><h3>Methods</h3><p>The k-space arrangement of bright-blood images in the conventional VISIBLE followed a low-to-high frequency order, whereas that in the proposed VISIBLE sequence was in the reversed order, and a startup echo was added. The effects of startup echo on the signal-to-noise ratio (SNR) were evaluated using phantoms, considering both white matter (WM) and post-contrast blood. Data from copper sulfate phantoms were acquired in 1D Fourier transform mode using both the conventional and proposed methods of the two VISIBLE sequences. The signal behavior with each sequence was evaluated. Fourteen patients with a total of 21 metastases were included in the study. For each patient, VISIBLE images of both conventional and proposed methods were obtained consecutively after the contrast agent administration. Using clinical images, we conducted a comparison of the SNR and contrast-to-noise ratio (CNR) for tumors, normal WM, and blood vessels between the conventional and proposed VISIBLE sequences.</p></div><div><h3>Results</h3><p>There was no significant difference in SNRs for both black- and bright-blood images between the conventional sequence and the proposed sequence with different number of startup echoes, however, the SNR of the proposed sequence decreased with increasing number of startup echoes in both black- and bright-images. The signal behavior of the bright-blood image reached a “steady state” when the startup echo exceeded 20. The SNRs of blood vessels in the bright-blood images did not differ significantly between conventional and proposed VISIBLE sequences. The SNRs of WM in the bright-blood images was significantly larger in the conventional sequence than in the proposed sequence. The SNRs of tumors in bright blood images was significantly larger in the proposed sequence than in the conventional sequence. The CNRs between tumors and WM, vessels and WM in the bright-blood images were significantly higher in the proposed sequence than in the conventional sequence.</p></div><div><h3>Conclusion</h3><p>The use of the startup echo in combination with the high-to-low frequency k-space ordering method resulted in improved CNR of the bright-blood images in the VISIBLE sequence.</p></div>","PeriodicalId":18165,"journal":{"name":"Magnetic resonance imaging","volume":"112 ","pages":"Pages 144-150"},"PeriodicalIF":2.1,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141727392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Homogeneous B0 coil design method for open-access ultra-low field magnetic resonance imaging: A simulation study","authors":"Tomohiro Karasawa ,&nbsp;Jiro Saikawa ,&nbsp;Tatsuya Munaka ,&nbsp;Tetsuo Kobayashi","doi":"10.1016/j.mri.2024.07.006","DOIUrl":"10.1016/j.mri.2024.07.006","url":null,"abstract":"<div><p>A multimodal brain function measurement system integrating functional magnetic resonance imaging (fMRI) and magnetoencephalography (MEG) is expected to be a tool that will provide new insights into neuroscience. To integrate fMRI and MEG, an ultra-low-field MRI (ULF-MRI) scanner that can generate a static magnetic field (B0) with an electromagnetic coil and turn off the B0 during MEG measurements is desirable. While electromagnetic B0 coil has the above advantages, it also has a trade-off between size and the broadness of the magnetic field homogeneity. In this study, we proposed a method for designing a B0 multi-stage circular coil arrangement that determines the number of coils required to maximize magnetic field homogeneity and minimize the total wiring length of the coils. The optimized multi-stage coil arrangement had an external shape of 600 mm in diameter and a maximum height of 600 mm, with an aperture of 600 mm in diameter and 300 mm in height. The magnetic field homogeneity was &lt;100 ppm over a 210 mm diameter spherical volume (DSV). Compared to a previous two coil pairs arrangement with the same magnetic field homogeneity, the diameter was 1/1.9 times smaller, indicating that the newly designed B0 coil arrangement realized a smaller size and wider magnetic field homogeneity.</p></div>","PeriodicalId":18165,"journal":{"name":"Magnetic resonance imaging","volume":"112 ","pages":"Pages 128-135"},"PeriodicalIF":2.1,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141580134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combination of IVIM with DCE-MRI for diagnostic and prognostic evaluation of breast cancer","authors":"","doi":"10.1016/j.mri.2024.07.003","DOIUrl":"10.1016/j.mri.2024.07.003","url":null,"abstract":"<div><h3>Purpose</h3><p>To identify the most effective combination of DCE-MRI (<em>K</em>^{<em>trans</em>}<em>,K</em>_<em>ep</em>) and IVIM (<em>D,f</em>) and analyze the correlations of these parameters with prognostic indicators (ER, PR, and HER2, Ki-67 index, axillary lymph node (ALN) and tumor size) to improve the diagnostic and prognostic efficiency in breast cancer.</p></div><div><h3>Methods</h3><p>This is a prospective study. We performed T1WI, T2WI, IVIM, DCE-MRI at 3 T MRI examinations on benign and malignant breast lesions that met the inclusion criteria. We also collected pathological results of corresponding lesions, including ER, PR, and HER2, Ki-67 index, axillary lymph node (ALN) and tumor size. The diagnostic efficacy of DCE-MRI, IVIM imaging, and their combination for benign and malignant breast lesions was assessed. Correlations between the DCE-MRI and IVIM parameters and prognostic indicators were assessed.</p></div><div><h3>Results</h3><p>Overall,59 female patients with 62 lesions (22 benign lesions and 40 malignant lesions) were included in this study. The malignant group showed significantly lower D values (<em>p</em> &lt; 0.05) and significantly higher <em>K</em>^{<em>trans</em>}<em>, K</em>_<em>ep</em>, and <em>f</em> values (<em>p</em> &lt; 0.05). The AUC values of DCE, IVIM, DCE + IVIM were 0.828, 0.882, 0.901. <em>K</em>^{<em>trans</em>}<em>, K</em>_<em>ep</em><em>, D</em> and <em>f</em> values were correlated with the pathological grade (<em>p</em> &lt; 0.05); <em>K</em>^{<em>trans</em>} was negatively correlated with ER expression (<em>r</em> = −0.519, <em>p</em> &lt; 0.05); <em>K</em>_<em>ep</em> was correlated with PR expression and the Ki-67 index (<em>r</em> = −0.489, 0.330, <em>p</em> &lt; 0.05); the DCE and IVIM parameters showed no significant correlations with the HER2 and ALN (<em>p</em> &gt; 0.05). Tumor diameter was correlated with the <em>K</em>_<em>ep</em><em>, D</em> and <em>f</em> values (<em>r</em> = 0.246, −0.278, 0.293; <em>p</em> &lt; 0.05).</p></div><div><h3>Conclusion</h3><p>IVIM and DCE-MRI allowed differential diagnosis of benign and malignant breast lesions, and their combination showed significantly better diagnostic efficiency. DCE- and IVIM-derived parameters showed correlations with some prognostic factors for breast cancer.</p></div>","PeriodicalId":18165,"journal":{"name":"Magnetic resonance imaging","volume":"113 ","pages":"Article 110204"},"PeriodicalIF":2.1,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141545012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Three-dimensional simultaneous T1 and T2* relaxation times and quantitative susceptibility mapping at 3 T: A multicenter validation study","authors":"Shohei Fujita ,&nbsp;Akifumi Hagiwara ,&nbsp;Koichiro Kimura ,&nbsp;Yo Taniguchi ,&nbsp;Kosuke Ito ,&nbsp;Hisako Nagao ,&nbsp;Masahiro Takizawa ,&nbsp;Wataru Uchida ,&nbsp;Koji Kamagata ,&nbsp;Ukihide Tateishi ,&nbsp;Shigeki Aoki","doi":"10.1016/j.mri.2024.07.004","DOIUrl":"10.1016/j.mri.2024.07.004","url":null,"abstract":"<div><p>We aimed to determine the intra-site repeatability and cross-site reproducibility of T1 and T2* relaxation times and quantitative susceptibility (χ) values obtained through quantitative parameter mapping (QPM) at 3 T. This prospective study included three 3-T scanners with the same hardware and software platform at three sites. The brains of twelve healthy volunteers were scanned three times using QPM at three sites. Intra-site repeatability and cross-site reproducibility were evaluated based on voxel-wise and region-of-interest analyses. The within-subject coefficient of variation (wCV), within-subject standard deviation (wSD), linear regression, Bland–Altman plot, and intraclass correlation coefficient (ICC) were used for evaluation. The intra-site repeatability wCV was 11.9 ± 6.86% for T1 and 3.15 ± 0.03% for T2*, and wSD of χ at 3.35 ± 0.10 parts per billion (ppb). Intra-site ICC(1,<em>k</em>) values for T1, T2*, and χ were 0.878–0.904, 0.972–0.976, and 0.966–0.972, respectively, indicating high consistency within the same scanner. Linear regression analysis revealed a strong agreement between measurements from each site and the site-average measurement, with R-squared values ranging from 0.79 to 0.83 for T1, 0.94–0.95 for T2*, and 0.95–0.96 for χ. The cross-site wCV was 13.4 ± 5.47% for T1 and 3.69 ± 2.25% for T2*, and cross-site wSD of χ at 4.08 ± 3.22 ppb. The cross-site ICC(2,1) was 0.707, 0.913, and 0.902 for T1, T2*, and χ, respectively. QPM provides T1, T2*, and χ values with an intra-site repeatability of &lt;12% and cross-site reproducibility of &lt;14%. These findings may contribute to the development of multisite studies.</p></div>","PeriodicalId":18165,"journal":{"name":"Magnetic resonance imaging","volume":"112 ","pages":"Pages 100-106"},"PeriodicalIF":2.1,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141545017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quiescent frame, contrast-enhanced coronary magnetic resonance angiography reconstructed using limited number of physiologic frames from 5D free-running acquisitions","authors":"","doi":"10.1016/j.mri.2024.07.008","DOIUrl":"10.1016/j.mri.2024.07.008","url":null,"abstract":"<div><h3>Background</h3><p>5D, free-running imaging resolves sets of 3D whole-heart images in both cardiac and respiratory dimensions. In an application such as coronary imaging when a single, static image is of interest, computationally expensive offline iterative reconstruction is still needed to compute the multiple 3D datasets.</p></div><div><h3>Purpose</h3><p>Evaluate how the number of physiologic bins included in the reconstruction affects the computational cost and resulting image quality of a single, static volume reconstruction.</p></div><div><h3>Study type</h3><p>Retrospective.</p></div><div><h3>Subjects</h3><p>15 pediatric patients following Ferumoxytol infusion (4 mg/kg).</p></div><div><h3>Field strength/Sequence</h3><p>1.5 T/Ungated 5D free-running GRE sequence.</p></div><div><h3>Assessment</h3><p>The raw data of each subject were binned and reconstructed into a 5D (x-y-z-cardiac-respiratory) images. 1, 3, 5, 7, and 9 bins adjacent to both sides of the retrospectively determined cardiac resting phase and 1, 3 bins adjacent to the end-expiration phase are used for limited frame reconstructions. The static volume within each limited reconstruction was compared with the corresponding full 5D reconstruction using the structural similarity index measure (SSIM). A non-linear regression model was used to fit SSIM with the percentage of data used compared to full reconstruction (% data). A linear regression model was used to fit computation time with % raw data used. Coronary artery sharpness is measured on each limited reconstructed images to determine the minimal number of cardiac and respiratory bins needed to preserve image quality.</p></div><div><h3>Statistical tests</h3><p>The coefficient of determination (R²) is computed for each regression model.</p></div><div><h3>Results</h3><p>The % of data used in the reconstruction was linearly related to the computational time (R² = 0.99). The SSIM of the static image from the limited reconstructions is non-linearly related with the % of data used (R² = 0.80). Over the 15 patients, the model showed SSIM of 0.9 with 18% of data, and SSIM of 0.96 with 30% of data. The coronary artery sharpness of images reconstructed using no less than 5 cardiac and all respiratory phases is not significantly different from the full reconstructed images using all cardiac and respiratory bins.</p></div><div><h3>Data conclusion</h3><p>Reconstruction using only a limited number of acquired physiological states can linearly reduce the computational cost while preserving similarity to the full reconstruction image. It is suggested to use no less than 5 cardiac and all respiratory phases in the limited reconstruction to best preserve the original quality seen on the full reconstructed images.</p></div>","PeriodicalId":18165,"journal":{"name":"Magnetic resonance imaging","volume":"113 ","pages":"Article 110209"},"PeriodicalIF":2.1,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141555173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison and precision of visceral adipose tissue measurement techniques in a multisite longitudinal study using MRI","authors":"Samuel Barnes ,&nbsp;Erica Kinne ,&nbsp;Shilpy Chowdhury ,&nbsp;Spencer Loong ,&nbsp;Jeremy Moretz ,&nbsp;Joan Sabate","doi":"10.1016/j.mri.2024.07.002","DOIUrl":"10.1016/j.mri.2024.07.002","url":null,"abstract":"<div><h3>Background</h3><p>Measurement of visceral adipose tissue (VAT) using magnetic resonance imaging (MRI) is considered accurate and safe. Single slice measurements perform similar to volumetric measurements for cross-sectional observation studies but may not perform as well for longitudinal studies. This study compared the performance of single slice to volumetric VAT measurements in a prospective longitudinal study. Consistency of results across sites and over time was also evaluated.</p></div><div><h3>Methods</h3><p>A total of 935 healthy participants were recruited and scanned with MRI twice, approximately six months apart as part of a randomized, controlled, parallel arm, unblinded study conducted at four clinical centers in the United States. A 3D Dixon MRI sequence was used to image the abdomen, and visceral fat volumes were quantified for the abdomen, reduced coverage volumes (11 and 25 slices), and at single slices positioned at anatomical landmarks. A traveling phantom was scanned twice at all imaging sites.</p></div><div><h3>Results</h3><p>The correlation of single slice VAT measurement to full abdomen volumetric measurements ranged from 0.78 to 0.93 for cross-sectional observation measurements and 0.30 to 0.55 for longitudinal change. Reduced coverage volumetric measurement outperformed single slice measurements but still showed improved precision with more slices with cross-sectional observation and longitudinal correlations of 0.94 and 0.66 for 11 slices and 0.94 and 0.70 for 25 slices, respectively. No significant differences were observed across sites or over time with the traveling phantom and the volume measurements had a standard deviation of 14.1 mL, 2.6% of the measured volume.</p></div><div><h3>Conclusion</h3><p>Single slice VAT measurements had significantly lower correlation with abdomen VAT volume for longitudinal change than for cross-sectional observation measurements and may not be suitable for longitudinal studies. Data from multiple sites, different scanners, and over time did not show significant differences.</p></div>","PeriodicalId":18165,"journal":{"name":"Magnetic resonance imaging","volume":"112 ","pages":"Pages 82-88"},"PeriodicalIF":2.1,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0730725X24001802/pdfft?md5=545a88e43f4095dd8931fba6d8fac079&pid=1-s2.0-S0730725X24001802-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141545013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radiomics-based analysis of dynamic contrast-enhanced magnetic resonance image: A prediction nomogram for lymphovascular invasion in breast cancer","authors":"Xiuqi Yang ,&nbsp;Xuefei Wang ,&nbsp;Zhichao Zuo ,&nbsp;Weihua Zeng ,&nbsp;Haibo Liu ,&nbsp;Lu Zhou ,&nbsp;Yizhou Wen ,&nbsp;Chuang Long ,&nbsp;Siying Tan ,&nbsp;Xiong Li ,&nbsp;Ying Zeng","doi":"10.1016/j.mri.2024.07.001","DOIUrl":"10.1016/j.mri.2024.07.001","url":null,"abstract":"<div><h3>Objective</h3><p>To develop and validate a nomogram for quantitively predicting lymphovascular invasion (LVI) of breast cancer (BC) based on dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) radiomics and morphological features.</p></div><div><h3>Methods</h3><p>We retrospectively divided 238 patients with BC into training and validation cohorts. Radiomic features from DCE-MRI were subdivided into A1 and A2, representing the first and second post-contrast images respectively. We utilized the minimal redundancy maximal relevance filter to extract radiomic features, then we employed the least absolute shrinkage and selection operator regression to screen these features and calculate individualized radiomics score (Rad score). Through the application of multivariate logistic regression, we built a prediction nomogram that integrated DCE-MRI radiomics and MR morphological features (MR-MF). The diagnostic capabilities were evaluated by comparing C-indices and calibration curves.</p></div><div><h3>Results</h3><p>The diagnostic efficiency of the A1/A2 radiomics model surpassed that of the A1 and A2 alone. Furthermore, we incorporated the MR-MF (diffusion-weighted imaging rim sign, peritumoral edema) and optimized Radiomics into a hybrid nomogram. The C-indices for the training and validation cohorts were 0.868 (95% CI: 0.839–0.898) and 0.847 (95% CI: 0.787–0.907), respectively, indicating a good level of discrimination. Moreover, the calibration plots demonstrated excellent agreement in the training and validation cohorts, confirming the effectiveness of the calibration.</p></div><div><h3>Conclusion</h3><p>This nomogram combined MR-MF and A1/A2 Radiomics has the potential to preoperatively predict LVI in patients with BC.</p></div>","PeriodicalId":18165,"journal":{"name":"Magnetic resonance imaging","volume":"112 ","pages":"Pages 89-99"},"PeriodicalIF":2.1,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141545015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multimodal surface coils for low field MR imaging","authors":"Yunkun Zhao ,&nbsp;Aditya A. Bhosale ,&nbsp;Xiaoliang Zhang","doi":"10.1016/j.mri.2024.07.005","DOIUrl":"10.1016/j.mri.2024.07.005","url":null,"abstract":"<div><p>Low field MRI is safer and more cost effective than the high field MRI. One of the inherent problems of low field MRI is its low signal-to-noise ratio or sensitivity. In this work, we introduce a multimodal surface coil technique for signal excitation and reception to improve the RF magnetic field (B₁) efficiency and potentially improve MR sensitivity. The proposed multimodal surface coil consists of multiple identical resonators that are electromagnetically coupled to form a multimodal resonator. The field distribution of its lowest frequency mode is suitable for MR imaging applications. The prototype multimodal surface coils are built, and the performance is investigated and validated through numerical simulation, standard RF measurements and tests, and comparison with the conventional surface coil at low fields. Our results show that the B₁ efficiency of the multimodal surface coil outperforms that of the conventional surface coil which is known to offer the highest B₁ efficiency among all coil categories, i.e., volume coil, half-volume coil and surface coil. In addition, in low-field MRI, the required low-frequency coils often use large value capacitance to achieve the low resonant frequency which makes frequency tuning difficult. The proposed multimodal surface coil can be conveniently tuned to the required low frequency for low-field MRI with significantly reduced capacitance value, demonstrating excellent low-frequency operation capability over the conventional surface coil.</p></div>","PeriodicalId":18165,"journal":{"name":"Magnetic resonance imaging","volume":"112 ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141545014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}