Sabine F. Bensamoun , Kiaran P. McGee , Mashhour Chakouch , Philippe Pouletaut , Fabrice Charleux
{"title":"Monitoring of lung stiffness for long-COVID patients using magnetic resonance elastography (MRE)","authors":"Sabine F. Bensamoun , Kiaran P. McGee , Mashhour Chakouch , Philippe Pouletaut , Fabrice Charleux","doi":"10.1016/j.mri.2024.110269","DOIUrl":"10.1016/j.mri.2024.110269","url":null,"abstract":"<div><h3>Purpose</h3><div>Transaxial CT imaging is the main clinical imaging modality for the assessment of COVID-induced lung damage. However, this type of data does not quantify the functional properties of the lung. The objective is to provide non-invasive personalized cartographies of lung stiffness for long-COVID patients using MR elastography (MRE) and follow-up the evolution of this quantitative mapping over time.</div></div><div><h3>Methods</h3><div>Seven healthy and seven long-COVID participants underwent CT and MRE imaging at total lung capacity. After CT test, a senior radiologist visually analyzed the lung structure. Less than one month later, a first MRI (1.5 T, GRE sequence) lung density test followed by a first MRE (SE-EPI sequence) test were performed. Gadolinium-doped water phantom and a pneumatic driver (vibration frequency: 50 Hz), placed on the sternum, were used for MRI and MRE tests, respectively. Personalized cartographies of the stiffness were obtained, by two medical imaging engineers, using a specific post processing (MMDI algorithm). The monitoring (lung density, stiffness) was carried out no later than 11 months for each COVID patient. Wilcoxon's tests and an intra-class correlation coefficient (ICC) were used for statistical analysis.</div></div><div><h3>Results</h3><div>The density for long-COVID patients was significantly (<em>P</em> = 0.047) greater (170 kg.m<sup>−3</sup>) compared to healthy (125 kg.m<sup>−3</sup>) subjects. After the first MRE test, the stiffness measured for the healthy subjects was in the same range (median value (interquartile range, IQR): 0.93 (0.09) kPa), while the long-COVID patients showed a larger stiffness range (from 1.39 kPa to 2.05 kPa). After a minimum delay of 5 months, the second MRE test showed a decrease of stiffness (from 22 % to 40 %) for every long-COVID patient. The inter-operator agreement was excellent (intra-class correlation coefficient: 0.93 [0.78–0.97]).</div></div><div><h3>Conclusion</h3><div>The MRE test is sensitive enough to monitor disease-induced change in lung stiffness (increase with COVID symptoms and decrease with recovery). This non-invasive modality could yield complementary information as a new imaging biomarker to follow up long-COVID patients.</div></div>","PeriodicalId":18165,"journal":{"name":"Magnetic resonance imaging","volume":"115 ","pages":"Article 110269"},"PeriodicalIF":2.1,"publicationDate":"2024-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142568720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
George Yiasemis , Nikita Moriakov , Jan-Jakob Sonke , Jonas Teuwen
{"title":"vSHARP: Variable Splitting Half-quadratic ADMM algorithm for reconstruction of inverse-problems","authors":"George Yiasemis , Nikita Moriakov , Jan-Jakob Sonke , Jonas Teuwen","doi":"10.1016/j.mri.2024.110266","DOIUrl":"10.1016/j.mri.2024.110266","url":null,"abstract":"<div><div>Medical Imaging (MI) tasks, such as accelerated parallel Magnetic Resonance Imaging (MRI), often involve reconstructing an image from noisy or incomplete measurements. This amounts to solving ill-posed inverse problems, where a satisfactory closed-form analytical solution is not available. Traditional methods such as Compressed Sensing (CS) in MRI reconstruction can be time-consuming or prone to obtaining low-fidelity images. Recently, a plethora of Deep Learning (DL) approaches have demonstrated superior performance in inverse-problem solving, surpassing conventional methods. In this study, we propose vSHARP (variable Splitting Half-quadratic ADMM algorithm for Reconstruction of inverse Problems), a novel DL-based method for solving ill-posed inverse problems arising in MI. vSHARP utilizes the Half-Quadratic Variable Splitting method and employs the Alternating Direction Method of Multipliers (ADMM) to unroll the optimization process. For data consistency, vSHARP unrolls a differentiable gradient descent process in the image domain, while a DL-based denoiser, such as a U-Net architecture, is applied to enhance image quality. vSHARP also employs a dilated-convolution DL-based model to predict the Lagrange multipliers for the ADMM initialization. We evaluate vSHARP on tasks of accelerated parallel MRI Reconstruction using two distinct datasets and on accelerated parallel dynamic MRI Reconstruction using another dataset. Our comparative analysis with state-of-the-art methods demonstrates the superior performance of vSHARP in these applications.</div></div>","PeriodicalId":18165,"journal":{"name":"Magnetic resonance imaging","volume":"115 ","pages":"Article 110266"},"PeriodicalIF":2.1,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142503198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emma Friesen , Madison Chisholm , Bibek Dhakal , Morgan Mercredi , Mark D. Does , John C. Gore , Melanie Martin
{"title":"Corrigendum to “Modelling white matter microstructure using diffusion OGSE MRI: Model and analysis choices” [Magnetic Resonance Imaging 113 (2024) 110221]","authors":"Emma Friesen , Madison Chisholm , Bibek Dhakal , Morgan Mercredi , Mark D. Does , John C. Gore , Melanie Martin","doi":"10.1016/j.mri.2024.110265","DOIUrl":"10.1016/j.mri.2024.110265","url":null,"abstract":"","PeriodicalId":18165,"journal":{"name":"Magnetic resonance imaging","volume":"115 ","pages":"Article 110265"},"PeriodicalIF":2.1,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142503199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Moritz Becker, Filip Arvidsson, Jonas Bertilson, Elene Aslanikashvili, Jan G. Korvink, Mazin Jouda, Sören Lehmkuhl
{"title":"Deep learning corrects artifacts in RASER MRI profiles","authors":"Moritz Becker, Filip Arvidsson, Jonas Bertilson, Elene Aslanikashvili, Jan G. Korvink, Mazin Jouda, Sören Lehmkuhl","doi":"10.1016/j.mri.2024.110247","DOIUrl":"10.1016/j.mri.2024.110247","url":null,"abstract":"<div><div>A newly developed magnetic resonance imaging (MRI) approach is based on “Radiowave amplification by the stimulated emission of radiation” (RASER). RASER MRI potentially allows for higher resolution, is inherently background-free, and does not require radio-frequency excitation. However, RASER MRI can be “nearly unusable” as heavy distortions from nonlinear effects can occur. In this work, we show that deep learning (DL) reduces such artifacts in RASER images. We trained a two-step DL pipeline on purely synthetic data, which was generated based on a previously published, theoretical model for RASER MRI. A convolutional neural network was trained on 630′000 1D RASER projections, and a U-net on 2D random images. The DL pipeline generalizes well when applied from synthetic to experimental RASER MRI data.</div></div>","PeriodicalId":18165,"journal":{"name":"Magnetic resonance imaging","volume":"115 ","pages":"Article 110247"},"PeriodicalIF":2.1,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142503197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xue Bi , Xinwen Liu , Zhifeng Chen , Hongli Chen , Yajun Du , Huizu Chen , Xiaoli Huang , Feng Liu
{"title":"Complex-valued image reconstruction for compressed sensing MRI using hierarchical constraint","authors":"Xue Bi , Xinwen Liu , Zhifeng Chen , Hongli Chen , Yajun Du , Huizu Chen , Xiaoli Huang , Feng Liu","doi":"10.1016/j.mri.2024.110267","DOIUrl":"10.1016/j.mri.2024.110267","url":null,"abstract":"<div><div>In Magnetic Resonance Imaging (MRI), the sequential acquisition of raw complex-valued image data in Fourier space, also known as k-space, results in extended examination times. To speed up the MRI scans, k-space data are usually undersampled and processed using numerical techniques such as compressed sensing (CS). While the majority of CS-MRI algorithms primarily focus on magnitude images due to their significant diagnostic value, the phase components of complex-valued MRI images also hold substantial importance for clinical diagnosis, including neurodegenerative diseases. In this work, complex-valued MRI reconstruction is studied with a focus on the simultaneous reconstruction of both magnitude and phase images. The proposed algorithm is based on the nonsubsampled contourlet transform (NSCT) technique, which offers shift invariance in images. Instead of directly transforming the complex-valued image into the NSCT domain, we introduce a wavelet transform within the NSCT domain, reducing the size of the sparsity of coefficients. This two-level hierarchical constraint (HC) enforces sparse representation of complex-valued images for CS-MRI implementation. The proposed HC is seamlessly integrated into a proximal algorithm simultaneously. Additionally, to effectively minimize the artifacts caused by sub-sampling, thresholds related to different sub-bands in the HC are applied through an alternating optimization process. Experimental results show that the novel method outperforms existing CS-MRI techniques in phase-regularized complex-valued image reconstructions.</div></div>","PeriodicalId":18165,"journal":{"name":"Magnetic resonance imaging","volume":"115 ","pages":"Article 110267"},"PeriodicalIF":2.1,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142503196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yijin Yang , Boqiao Zhang , Ming Lu , Xinqiang Yan
{"title":"Dual-tuned floating solenoid balun for multi-nuclear MRI and MRS","authors":"Yijin Yang , Boqiao Zhang , Ming Lu , Xinqiang Yan","doi":"10.1016/j.mri.2024.110268","DOIUrl":"10.1016/j.mri.2024.110268","url":null,"abstract":"<div><div>Common-mode currents can degrade the RF coil performance and introduce potential safety hazards in MRI. Baluns are the standard method to suppress these undesired common-mode currents. Specifically, floating baluns are preferred in many applications because they are removable, allow post-installation adjustment and avoid direct soldering on the cable. However, floating baluns are typically bulky to achieve excellent common-mode suppression, taking up valuable space in the MRI bore. This is particularly severe for multi-nuclear MRI/MRS applications, as two RF systems exist. In this work, we present a novel dual-tuned floating balun that is fully removable, does not require any physical connection to the coaxial cable, and has a significantly reduced footprint. The floating design employs an inductive coupling between the cable solenoid and a floating solenoid resonator rather than a direct physical connection. Unlike the previous floating solenoid balun, this balun employs a two-layer design further to improve the mutual coupling between the two solenoids. A pole-insertion method is used to suppress common-mode currents at two user-selectable frequencies simultaneously. Bench testing of the fabricated device at 7 T demonstrated high common-mode rejection ratios at Larmor frequencies of both <sup>1</sup>H and <sup>23</sup>Na, even with a compact dimension (diameter 18 mm and length 12 mm). This balun's removable, compact, and multi-resonant nature enables light-weighting, allows more coil elements, and improves cable management for advanced multi-nuclear MRI/MRS systems.</div></div>","PeriodicalId":18165,"journal":{"name":"Magnetic resonance imaging","volume":"115 ","pages":"Article 110268"},"PeriodicalIF":2.1,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142503200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hsiang-Yu Yu , Cheng Jui Tsai , Tse-Hao Lee , Hsin Tung , Yen-Cheng Shih , Chien-Chen Chou , Cheng-Chia Lee , Po-Tso Lin , Syu-Jyun Peng
{"title":"Machine learning localization to identify the epileptogenic side in mesial temporal lobe epilepsy","authors":"Hsiang-Yu Yu , Cheng Jui Tsai , Tse-Hao Lee , Hsin Tung , Yen-Cheng Shih , Chien-Chen Chou , Cheng-Chia Lee , Po-Tso Lin , Syu-Jyun Peng","doi":"10.1016/j.mri.2024.110256","DOIUrl":"10.1016/j.mri.2024.110256","url":null,"abstract":"<div><h3>Background</h3><div>Mesial temporal sclerosis (MTS) is the most common pathology associated with drug-resistant mesial temporal lobe epilepsy (mTLE) in adults.</div><div>Most atrophic hippocampi can be identified using MRI based on standard epilepsy protocols; however, difficulties can arise in cases where sclerotic changes in the hippocampus are subtle or non-epilepsy-specific protocols have been implemented. In such cases, quantitative methods, such as T1-weighted axial series MRIs, are valuable additional tools to complement epilepsy-specific protocols. In the current study, we applied machine learning (ML) techniques to the analysis of brain regions of interest (ROIs), including the hippocampus, thalamus, and cortical areas, to enhance the accuracy of lesion lateralization in MRI.</div></div><div><h3>Methods</h3><div>This study included 104 patients diagnosed with mTLE, including 55 with lesions on the right side and 49 with lesions on the left side. FreeSurfer software was used to extract features from high-resolution T1-weighted axial brain MRI scans for use in computing lateralization indices (LI) for various brain regions. After using feature selection to pinpoint critical ROIs, the corresponding LI values were used as parameters in training the ML model.</div></div><div><h3>Results</h3><div>The proposed ML model demonstrated exceptional performance in the lateralization of mTLE, achieving test accuracy of 92.38 % with an AUROC of 0.97.</div></div><div><h3>Conclusion</h3><div>This study demonstrated the efficacy of ML in detecting instances of MTS from thin-slice T1 images. The proposed method provides valuable insights for surgical planning and treatment. Nonetheless, additional research will be required to enhance the robustness of the model and rigorously validate its effectiveness and applicability in clinical settings.</div></div>","PeriodicalId":18165,"journal":{"name":"Magnetic resonance imaging","volume":"115 ","pages":"Article 110256"},"PeriodicalIF":2.1,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142469127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bayesian merged utilization of GRAPPA and SENSE (BMUGS) for in-plane accelerated reconstruction increases fMRI detection power","authors":"Chase J. Sakitis, Daniel B. Rowe","doi":"10.1016/j.mri.2024.110252","DOIUrl":"10.1016/j.mri.2024.110252","url":null,"abstract":"<div><div>In fMRI, capturing brain activity during a task is dependent on how quickly the <em>k</em>-space arrays for each volume image are obtained. Acquiring the full <em>k</em>-space arrays can take a considerable amount of time. Under-sampling <em>k</em>-space reduces the acquisition time, but results in aliased, or “folded,” images after applying the inverse Fourier transform (IFT). GeneRalized Autocalibrating Partial Parallel Acquisition (GRAPPA) and SENSitivity Encoding (SENSE) are parallel imaging techniques that yield reconstructed images from subsampled arrays of <em>k</em>-space. With GRAPPA operating in the spatial frequency domain and SENSE in image space, these techniques have been separate but can be merged to reconstruct the subsampled <em>k</em>-space arrays more accurately. Here, we propose a Bayesian approach to this merged model where prior distributions for the unknown parameters are assessed from <em>a priori k</em>-space arrays. The prior information is utilized to estimate the missing spatial frequency values, unalias the voxel values from the posterior distribution, and reconstruct into full field-of-view images. Our Bayesian technique successfully reconstructed simulated and experimental fMRI time series with no aliasing artifacts while decreasing temporal variation and increasing task detection power.</div></div>","PeriodicalId":18165,"journal":{"name":"Magnetic resonance imaging","volume":"115 ","pages":"Article 110252"},"PeriodicalIF":2.1,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142469125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jianmin Wang , Chunyan Liu , Yuxiang Zhong , Xinling Liu , Jianjun Wang
{"title":"Deep plug-and-play MRI reconstruction based on multiple complementary priors","authors":"Jianmin Wang , Chunyan Liu , Yuxiang Zhong , Xinling Liu , Jianjun Wang","doi":"10.1016/j.mri.2024.110244","DOIUrl":"10.1016/j.mri.2024.110244","url":null,"abstract":"<div><div>Magnetic resonance imaging (MRI) is widely used in clinical diagnosis as a safe, non-invasive, high-resolution medical imaging technology, but long scanning time has been a major challenge for this technology. The undersampling reconstruction method has become an important technical means to accelerate MRI by reducing the data sampling rate while maintaining high-quality imaging. However, traditional undersampling reconstruction techniques such as compressed sensing mainly rely on relatively single sparse or low-rank prior information to reconstruct the image, which has limitations in capturing the comprehensive features of images, resulting in the insufficient performance of the reconstructed image in terms of details and key information. In this paper, we propose a deep plug-and-play multiple complementary priors MRI reconstruction model, which combines traditional low-rank matrix recovery model methods and deep learning methods, and integrates global, local and nonlocal priors to improve reconstruction quality. Specifically, we capture the global features of the image through the matrix nuclear norm, and use the deep convolutional neural network denoiser Swin-Conv-UNet (SCUNet) and block-matching and 3-D filtering (BM3D) algorithm to preserve the local details and structural texture of the image, respectively. In addition, we utilize an efficient half-quadratic splitting (HQS) algorithm to solve the proposed model. The experimental results show that our proposed method has better reconstruction ability than the existing popular methods in terms of visual effects and numerical results.</div></div>","PeriodicalId":18165,"journal":{"name":"Magnetic resonance imaging","volume":"115 ","pages":"Article 110244"},"PeriodicalIF":2.1,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142469126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Junxian Liao , Hongbiao Sun , Xin Chen, Qinling Jiang, Yuxin Cheng, Yi Xiao
{"title":"Advance in the application of 4-dimensional flow MRI in atrial fibrillation","authors":"Junxian Liao , Hongbiao Sun , Xin Chen, Qinling Jiang, Yuxin Cheng, Yi Xiao","doi":"10.1016/j.mri.2024.110254","DOIUrl":"10.1016/j.mri.2024.110254","url":null,"abstract":"<div><div>Atrial fibrillation (AF) is the most prevalent arrhythmia in world-wild places and is associated with the development of severe secondary complications such as heart failure and stroke. Emerging evidence shows that the modified hemodynamic environment associated with AF can cause altered flow patterns in left atrial and even systemic blood associated with left atrial appendage thrombosis. Recent advances in magnetic resonance imaging (MRI) allow for the comprehensive visualization and quantification of in vivo aortic flow pattern dynamics. In particular, the technique of 4- dimensional flow MRI (4D flow MRI) offers the opportunity to derive advanced hemodynamic measures such as velocity, vortex, endothelial cell activation potential, and kinetic energy. This review introduces 4D flow MRI for blood flow visualization and quantification of hemodynamic metrics in the setting of AF, with a focus on AF and associated secondary complications.</div></div>","PeriodicalId":18165,"journal":{"name":"Magnetic resonance imaging","volume":"115 ","pages":"Article 110254"},"PeriodicalIF":2.1,"publicationDate":"2024-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142441941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}