Macromolecular Materials and Engineering最新文献

{"title":"Processing–Structure–Degradation Relationships in Additively Manufactured and Cast PLA/PCL Blends","authors":"Fatemeh Sadat Mahdavi,&nbsp;Arunachalam Ramanathan,&nbsp;Xiao Sun,&nbsp;Dhanush Patil,&nbsp;Varunkumar Thippanna,&nbsp;Libin Yang,&nbsp;Sri Vaishnavi Thummalapalli,&nbsp;M. Taylor Sobczak,&nbsp;Chao Sui,&nbsp;Zhengfu Huang,&nbsp;Tiantian Li,&nbsp;Qixuan Xiang,&nbsp;Ian Doran,&nbsp;James Jaraczewski,&nbsp;Manlilang Luo,&nbsp;Jacob Houston,&nbsp;Nathan Newton,&nbsp;Kate Hwang,&nbsp;Robert Loos,&nbsp;Mike Parker,&nbsp;Haley Dayton,&nbsp;Mark Remmert,&nbsp;Gajanan Bhat,&nbsp;Smriti Rai,&nbsp;Kenan Song","doi":"10.1002/mame.70257","DOIUrl":"https://doi.org/10.1002/mame.70257","url":null,"abstract":"<p>This study explores the effects of varying polylactic acid (PLA) and polycaprolactone (PCL) blend ratios on the rheological properties, printability, and structural performance of scaffolds fabricated by electrohydrodynamic writing(EHD). The blends were prepared in weight ratios of 100/0, 90/10, 80/20, 70/30, 60/40, 50/50, and 0/100 (PLA/PCL) and systematically evaluated to determine their influence on ink viscosity, extrusion behavior, scaffold fidelity, and mechanical integrity. The results demonstrate that increasing PCL content reduces viscosity, enhancing extrudability and enabling finer resolution in printed structures. However, this requires careful optimization of printing pressure and nozzle diameter to maintain structural stability. Intermediate blends (e.g., 70/30 or 60/40) demonstrated the best balance between printability, mechanical strength, and controlled degradation, making them promising for tissue engineering applications. The study highlights the advantages of EHD as a precision additive manufacturing technique, enabling controllable degradation behavior through tuning of degradation kinetics via blend composition. Overall, this work demonstrates that optimizing PLA/PCL blend composition enables the fabrication of mechanically robust biopolymer structures with controlled degradation profiles, reinforcing their potential for food packaging, biomedical devices, or even the patient-specific tissue regeneration.</p>","PeriodicalId":18151,"journal":{"name":"Macromolecular Materials and Engineering","volume":"311 6","pages":""},"PeriodicalIF":5.2,"publicationDate":"2026-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mame.70257","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148281964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Semi-Automated Platform for Early Prenatal Coelocentesis Testing Using Electrospun Nanofiber Technology","authors":"Emanuela Muscolino,&nbsp;Anna Barbara Di Stefano,&nbsp;Santina Acuto,&nbsp;Clelia Dispenza","doi":"10.1002/mame.70255","DOIUrl":"https://doi.org/10.1002/mame.70255","url":null,"abstract":"<p>Prenatal diagnostics play a critical role in identifying fetal disease conditions, particularly rare genetic disorders that significantly contribute to infant morbidity and mortality. Despite major advances in sequencing technologies, nearly 80% of rare disease cases remain undiagnosed. Invasive procedures such as amniocentesis and chorionic villus sampling (CVS) provide valuable genetic information but are typically performed between the 15th and 20th weeks of gestation and carry a risk of miscarriage. Non-invasive prenatal testing (NIPT) offers a safer alternative; however, it lacks the resolution required to reliably detect rare monogenic diseases. Coelocentesis, an earlier sampling technique performed between 6 and 10 weeks of gestation through transvaginal aspiration of coelomic fluid, enables access to fetal cells at a much earlier stage. Its clinical utility is limited by the low number of available fetal cells and by labor-intensive isolation methods such as micromanipulation. This study proposes a semi-automated capture device based on electrospun nanofiber mats functionalized with antibodies targeting fetal-specific surface antigens. The high surface area and structural flexibility of the nanofibers enable efficient and selective capture from low-cellularity samples. Integration with microfluidic systems may streamline processing and improve diagnostic throughput.</p>","PeriodicalId":18151,"journal":{"name":"Macromolecular Materials and Engineering","volume":"311 6","pages":""},"PeriodicalIF":5.2,"publicationDate":"2026-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mame.70255","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148281987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preparation and Mapping of Alginate Morphologies Using Inverted Nozzle Pressurised Gyration","authors":"Jiaxuan Ren,&nbsp;Yanqi Dai,&nbsp;Angelo Delbusso,&nbsp;Shervanthi Homer-Vanniasinkam,&nbsp;Mohan Edirisinghe","doi":"10.1002/mame.70262","DOIUrl":"https://doi.org/10.1002/mame.70262","url":null,"abstract":"<p>This work facilitates the fabrication of alginate products from a natural <i>Laminaria</i> source using the newest pressure spinning method, inverted nozzle pressurized gyration (INPG). A coagulation bath with calcium chloride was used as the crosslinker to achieve the ion exchange for the formation of the “egg-box” structure. The present study investigates the effects of the concentration of spinning solution and coagulation bath, working distance, and pressure on product morphology. The aforementioned variables were found to have a significant impact on the structure and dimensions of the product. However, it should be noted that these variables often act in a complex and interconnected manner, and their influence is frequently the result of combined effects. Consequently, “mapping” was provided to summarize how the combination of parameters alters the morphology. Utilizing the analytical tools of FTIR and XRD, it has been demonstrated that the method employed in this study can be effectively applied to the regeneration of natural alginates. Despite the peak intensities of products displaying varying degrees of change in both spectra, the overall chemical composition as a result of the functional groups remained consistent with the raw material, and suggests that the products are composed of alginate.</p>","PeriodicalId":18151,"journal":{"name":"Macromolecular Materials and Engineering","volume":"311 6","pages":""},"PeriodicalIF":5.2,"publicationDate":"2026-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mame.70262","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148281986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electrospun PVA/PVP/Pectin Nanofibrous Patches Loaded with Hawthorn Extract and Dragon's Blood for Synergistic Wound Care","authors":"Moein Zarei,&nbsp;Jakub Trzciński,&nbsp;Dominik Baraniecki,&nbsp;Paulina Trzaskowska,&nbsp;Mustafa Alsarraf,&nbsp;Monika Staniszewska,&nbsp;Jagan Mohan Dodda,&nbsp;Tomáš Kovářík,&nbsp;Jaeyun Kim,&nbsp;Ewa Kijeńska-Gawrońska","doi":"10.1002/mame.202500463","DOIUrl":"https://doi.org/10.1002/mame.202500463","url":null,"abstract":"<p>With the rising occurrence of skin diseases such as atopic dermatitis (AD), which are often associated with inflammation, skin barrier damage, and related complications, there is an urgent need for simple and effective early-stage treatment strategies. Although current therapies, including moisturizers, injections, and corticosteroids, offer some relief, they present limitations such as side effects, high cost, or limited efficacy. Therefore, developing a straightforward therapeutic patch that promotes skin regeneration and enables efficient drug delivery is essential. In this study, electrospun nanofibrous patches composed of polyvinyl alcohol (PVA), polyvinylpyrrolidone (PVP), and pectin (PEC) were fabricated and loaded with Hawthorn Extract (HE) and Dragon's Blood (DB) to enhance wound healing capacity. The patches were comprehensively characterized by morphological, chemical, and functional analyses. Surface wettability, swelling, and in vitro release studies confirmed improved hydrophilicity, rapid fluid uptake, and sustained delivery of the plant extracts. Antifungal activity against <i>Candida albicans</i> showed that dual-extract patches completely inhibited fungal growth, while cytotoxicity assays with L929 fibroblasts confirmed biocompatibility. In vivo skin hydration testing on human volunteers demonstrated significant improvements, with dual-extract patches enhancing skin moisture by up to 44% over a 6-h period compared to the control group. These findings indicate that electrospun PVA/PVP/PEC patches, particularly those incorporating both HE and DB, combine hydration, antifungal properties, and biocompatibility. Such features highlight their strong potential for translation into clinical studies for treating AD and related chronic skin conditions.</p>","PeriodicalId":18151,"journal":{"name":"Macromolecular Materials and Engineering","volume":"311 6","pages":""},"PeriodicalIF":4.6,"publicationDate":"2026-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mame.202500463","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148237668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Consequences of Monomer Impurities on Network Characteristics and Dynamic Mechanical Behavior of an Eugenol-Based Covalent Adaptable Network","authors":"Robin Tannert,&nbsp;Andreas Taubert,&nbsp;Jens Weber","doi":"10.1002/mame.70247","DOIUrl":"https://doi.org/10.1002/mame.70247","url":null,"abstract":"<p>Covalent adaptable networks are an emerging class of polymer networks that exhibit high potential for recyclability. For industrial applications, the robustness of material properties and predictable dynamic behavior are highly desirable. In this study, diepoxides of varying purity were used to prepare <i>hybrid</i> CANs. Hybrid CANs are based on dynamic vinylogous urethane bonds <i>and</i> permanent bonds formed by the reaction of amines and epoxides. The robustness of the materials dynamic exchange behavior against impurities that impair or modify the network characteristics was specifically investigated. Stress relaxation experiments reveal that the dynamic behavior remains relatively stable up to ca. 23% monomer impurity. At higher impurity levels, we observe pronounced changes of the exchange dynamics. All materials, regardless of purity, exhibit incomplete stress relaxation because of the significant fraction of permanent bonds. As a consequence, visible defects (old fragment boundaries) remain visible after reprocessing of the nominally purest materials. We found that the network density and glass transition temperature decrease with increasing impurity, while overall the thermal stability remains largely unaffected. The results demonstrate that hybrid CANs based on vinylogous urethane exchange chemistry can tolerate moderate monomer impurities without losing key dynamic properties, offering insights for industrial-scale processing and material design.</p>","PeriodicalId":18151,"journal":{"name":"Macromolecular Materials and Engineering","volume":"311 6","pages":""},"PeriodicalIF":4.6,"publicationDate":"2026-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mame.70247","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148237667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High Strength, Healable, Recyclable Ionogel Capable of Long-term Load Cycling","authors":"Haoyu Wu,&nbsp;Tian Jiang","doi":"10.1002/mame.70252","DOIUrl":"https://doi.org/10.1002/mame.70252","url":null,"abstract":"<p>Ionogels have attracted growing interest as stretchable conductive materials for applications in soft robotics, electronic skins, and wearable electronics. However, achieving a system that integrates mechanical strength, self-healing, recyclability, and long-term durability under cyclic loading remains a significant challenge. Traditional designs often lack effective energy dissipation pathways, leading to fatigue accumulation during cyclic deformation. In this study, polyurethane elastomers were synthesized with adipic dihydrazide (ADDH) and imidazolidinyl urea (IAU) as chain extenders, and subsequently complexed with ionic liquids to form PU–IL ionogels. The acylsemicarbazide groups in ADDH form robust hydrogen bonds, analogous to the hard β-sheet nanocrystals in spider silk, while IAU introduces weaker hydrogen bonds that resemble the soft amorphous protein matrix. During stretching, the strong hydrogen bonds preserve structural integrity, while the weaker bonds reversibly break to dissipate energy. Consequently, the ionogels exhibit impressive mechanical properties, including a tensile strength of 12.6 MPa, toughness of 85.7 MJ m⁻³, excellent long-term cyclic load stability, and a broad strain sensitivity range (0.1%–200%). Additionally, the reversible hydrogen-bonding network facilitates polymer segment reorganization, enabling efficient self-healing and recyclability. This study proposes a hydrogen-bonding-enabled design strategy for high-performance ionogels, paving the way for next-generation flexible and wearable electronic applications.</p>","PeriodicalId":18151,"journal":{"name":"Macromolecular Materials and Engineering","volume":"311 6","pages":""},"PeriodicalIF":4.6,"publicationDate":"2026-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mame.70252","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148146952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biodegradable Materials Composed of PLA and High Load Triglycerides","authors":"Marie-Luise Trutschel,&nbsp;Detlef Reichert,&nbsp;Assam Raja,&nbsp;Jonas Jacobs,&nbsp;Muhammad Abdel-Haq,&nbsp;Awanish Kumar,&nbsp;Karsten Mäder,&nbsp;Abraham J Domb","doi":"10.1002/mame.70251","DOIUrl":"https://doi.org/10.1002/mame.70251","url":null,"abstract":"<p>The ability of biodegradable polymers, such as polylactic acid (PLA), to incorporate high amounts of triglycerides (10–50 w/w%) and remain solid transparent films was examined for the changes in polymer mechanical and thermal properties as a part of developing new biodegradable safe materials. In this context, sesame oil was used as common safe natural mixture of triglycerides. PLA loaded with 50% w/w of sesame oil content formed uniform flexible and optical transparent films. To understand the microscopic structure, in particular the homo or heterogeneous distribution of oil in polymer, blends with 10%–50% sesame oil and other vegetable oils were evaluated by low-field Nuclear Magnetic Resonance (NMR), Fourier Transform Infrared Spectroscopy (FTIR), Differential Scanning Calorimeter (DSC), X-ray photoelectron spectroscopy (XPS), X-ray Diffraction (XRD), and mechanical strength analysis. In addition to PLA, blends of polycaprolactone (PCL) with triglycerides were investigated as an alternative to an aliphatic polyester blend with lower glass transition temperature. On the molecular level, the data reveal a phase separation of oil and polymer in the PLA films with a close molecular interaction only occurring at the interface and a dispersion of the oil with immobilization by the polymer chains in the PCL films.</p>","PeriodicalId":18151,"journal":{"name":"Macromolecular Materials and Engineering","volume":"311 6","pages":""},"PeriodicalIF":4.6,"publicationDate":"2026-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mame.70251","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148146984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"TGA/DTA-Based Sintering Optimization of Al-Graphene-B4C Hybrid Composites and Effect on Mechanical and Tribological Behavior","authors":"Gürkan Soy,&nbsp;Büşranur Keser,&nbsp;Selda Kayral,&nbsp;Berk Yaylalı","doi":"10.1002/mame.70248","DOIUrl":"https://doi.org/10.1002/mame.70248","url":null,"abstract":"<p>Sintering is one of the most critical stages in powder metallurgy-produced composites, which directly affects density, microstructure, and interfacial bonding capability. In this study, graphene and B₄C-reinforced aluminum matrix hybrid composites were produced by the powder metallurgy method, and the effects of sintering temperature were evaluated using thermogravimetric analysis and differential thermal analysis (TGA/DTA) and X-Ray Diffraction (XRD) analyses. The density, hardness, and wear properties of the produced composites were determined experimentally. The optimum sintering temperatures were determined as 615°C for Al─Cu─Mg─Zn (AL0), 600°C for 0.5 wt.% graphene-reinforced composites (ALG05), and 614°C for hybrid composites reinforced with 0.5 wt.% graphene and 15 wt.% B₄C (ALG05B15). While the addition of graphene provided only a limited increase in hardness compared to the AL0 alloy, the hybrid composites achieved a significant improvement, reaching 100 HB. The wear test results indicated that the wear resistance of the hybrid composites was enhanced due to the increased matrix hardness and improved interfacial bonding. The lowest wear volume of 0.384 mm³, a specific wear rate of 5.12 × 10⁻⁴ mm³/N·m, and a coefficient of friction of 0.449 were obtained for the ALG05B15.2 hybrid composite sintered at 614°C.</p>","PeriodicalId":18151,"journal":{"name":"Macromolecular Materials and Engineering","volume":"311 6","pages":""},"PeriodicalIF":4.6,"publicationDate":"2026-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mame.70248","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148146954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultra-Fine Electroblown Nanofibrous Air Filters Produced From Recycled Textile Polyester Waste: Process Optimization and Electret Stability","authors":"Ali Toptaş","doi":"10.1002/mame.70249","DOIUrl":"https://doi.org/10.1002/mame.70249","url":null,"abstract":"<p>Textile-derived recycled polyester (rPET) cutting wastes are an abundant yet underutilized resource with limited high-value applications. This study demonstrates an upcycling strategy to convert low-value rPET shoddy and trimming residues into ultra-fine nanofibrous air filtration media via electroblowing. A three-factor response surface methodology (Box–Behnken design, 23 runs) was applied to optimize polymer concentration (7–13 wt.%), air pressure (0.5–3.5 bar), and feeding rate (2–10 mL/h) with respect to fiber diameter. The quadratic model showed strong predictive capability (R² = 97.53%), identifying concentration as the dominant parameter and revealing a non-linear thinning regime at low concentration. Under optimized conditions (≈7.75 wt.%, 3.5 bar, 2 mL/h; 30 kV, 30 cm), bead-free nanofibers with a mean diameter of 41 ± 14 nm were produced. Filtration performance evaluated using NaCl aerosols (0.26 ± 0.07 µm, 95 L/min) demonstrated a clear diameter–performance relationship. The ultra-fine sample exhibited high efficiency with moderate pressure drop, while corona treatment further enhanced performance, achieving up to 99.995% efficiency and improving the quality factor by 37%. Electret lifetime tests revealed minimal efficiency decay over one month, particularly for finer fibers. Overall, this work establishes a scalable electroblowing route for converting rPET waste into high-performance air filters.</p>","PeriodicalId":18151,"journal":{"name":"Macromolecular Materials and Engineering","volume":"311 6","pages":""},"PeriodicalIF":4.6,"publicationDate":"2026-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mame.70249","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148146955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Issue Information: Macromol. Mater. Eng. 6/2026","authors":"","doi":"10.1002/mame.70256","DOIUrl":"https://doi.org/10.1002/mame.70256","url":null,"abstract":"","PeriodicalId":18151,"journal":{"name":"Macromolecular Materials and Engineering","volume":"311 6","pages":""},"PeriodicalIF":4.6,"publicationDate":"2026-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mame.70256","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148146953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}