Macromolecular Materials and Engineering最新文献_第9页

Utilizing Liquid Crystalline Polymers as a Reinforcement Phase in the Fused Filament Fabrication with Conventional Polymers 利用液晶聚合物作为增强相制备传统聚合物熔丝

IF 4.2 3区材料科学

Macromolecular Materials and Engineering Pub Date : 2025-02-24 DOI: 10.1002/mame.202400441

Kai S. Johann, Lukas Schmitt, Christian Bonten

{"title":"Utilizing Liquid Crystalline Polymers as a Reinforcement Phase in the Fused Filament Fabrication with Conventional Polymers","authors":"Kai S. Johann, Lukas Schmitt, Christian Bonten","doi":"10.1002/mame.202400441","DOIUrl":"https://doi.org/10.1002/mame.202400441","url":null,"abstract":"Using thermotropic liquid crystalline polymers (LCP) in fused filament fabrication (FFF) facilitates the production of highly anisotropic parts that exhibit a high tensile strength and Young´s modulus in the printing direction. This work investigates, for the first time, an approach where the LCP (reinforcing phase) and a conventional polymer (matrix) are printed using two separate printer nozzles. This contrasts with the existing approach in literature, where both components are blended during filament extrusion and subsequently printed with a single printer nozzle. A polyamide 6/66 copolymer (CoPA), a polycarbonate (PC), and a polyetherketoneketone (PEKK) serve as conventional matrix polymers. Due to their chemical structure, a good compatibility is expected between each of these polymers with the LCP. Composite tensile samples are printed with 14, 23, and 30 vol.% LCP and subsequently characterized by uniaxial tensile testing. The highest Young's modulus of 6.8 GPa is achieved in PC/LCP samples with 30 vol.% LCP. In contrast, the highest tensile strength of 126 MPa is obtained in PEKK/LCP tensile samples with 30 vol.% LCP, after an additional thermal annealing at elevated temperatures. The main failure mechanism for all composites is an LCP pull-out, indicating a poor adhesion between the LCP and the matrix polymers.","PeriodicalId":18151,"journal":{"name":"Macromolecular Materials and Engineering","volume":"310 6","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mame.202400441","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144300363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Combining Selective Laser Sintering and Fused Deposition Modeling of Pharmaceutical Polymers: A Novel Approach to Prepare Intestine-Targeted Tablets 结合选择性激光烧结和熔融沉积的药物聚合物建模：制备肠道靶向片剂的新方法

IF 4.2 3区材料科学

Macromolecular Materials and Engineering Pub Date : 2025-02-20 DOI: 10.1002/mame.202400460

Thao Tranová, Kevin Matzick, Jan Loskot, Jana Macháčková, Marie Nevyhoštěná, Oliver Macho, Vladimíra Trnčáková, Alena Komersová, Jitka Mužíková

{"title":"Combining Selective Laser Sintering and Fused Deposition Modeling of Pharmaceutical Polymers: A Novel Approach to Prepare Intestine-Targeted Tablets","authors":"Thao Tranová, Kevin Matzick, Jan Loskot, Jana Macháčková, Marie Nevyhoštěná, Oliver Macho, Vladimíra Trnčáková, Alena Komersová, Jitka Mužíková","doi":"10.1002/mame.202400460","DOIUrl":"https://doi.org/10.1002/mame.202400460","url":null,"abstract":"This study introduces a novel approach to prepare an intestine-targeting transport system with a controlled drug release profile, combining two 3D printing techniques: selective laser sintering (SLS) and fused deposition modeling (FDM). Material evaluations indicate that a mixture of Kollidon® VA64 with 20% of Kollicoat® IR and 0.2% of Aeroperl® has the best flow behavior and exhibits optimal printability at a laser speed of 90 mm s−1. The formulation is subsequently drug-loaded and the printed cores are coated using the FDM technique. The core serves as a drug carrier and the FDM coating shell, consisting of 95% HPMC and 5% pectin, provides modified drug release and enhanced mechanical resistance of the tablet. The coating exhibits acid-resistant properties, with no drug release in the pH of 1.2 during the first 120 min of dissolution testing. In the pH of 6.8, the release profile shows zero-order kinetics with a constant release rate of 0.249% min−1 (in the time interval from 255 to 480 min). At the time point of 720 min, 92% of the drug is released. Dissolution testing thus demonstrates delayed and prolonged drug release. Combining both 3D printing methods shows great potential for personalized treatment of intestinal inflammatory diseases.","PeriodicalId":18151,"journal":{"name":"Macromolecular Materials and Engineering","volume":"310 6","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mame.202400460","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144300314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Catalase-Encapsulated Nanoparticles via Surface Radical Polymerization for Periodontitis Therapy 过氧化氢酶包封纳米粒子表面自由基聚合治疗牙周炎

IF 4.2 3区材料科学

Macromolecular Materials and Engineering Pub Date : 2025-02-20 DOI: 10.1002/mame.202500022

Tongtong Yan, Xiang Li, Shiqun Sun, Yuchao Luo, Haotian Shi, Nan Yang, Xue Ren, Wenjing Tian, Zhihui Liu, Bin Xu

{"title":"Catalase-Encapsulated Nanoparticles via Surface Radical Polymerization for Periodontitis Therapy","authors":"Tongtong Yan, Xiang Li, Shiqun Sun, Yuchao Luo, Haotian Shi, Nan Yang, Xue Ren, Wenjing Tian, Zhihui Liu, Bin Xu","doi":"10.1002/mame.202500022","DOIUrl":"https://doi.org/10.1002/mame.202500022","url":null,"abstract":"Periodontitis is a prevalent chronic inflammatory disease characterized by oxidative stress and excessive production of reactive oxygen species (ROS), leading to the destruction of periodontal tissues. Despite existing treatments, the management of periodontitis remains challenging due to inadequate control of inflammation and poor tissue regeneration. In this study, a novel therapeutic strategy is developed by encapsulating catalase (CAT) within polyacrylamide (PAAM)-based nanoparticles (CAT NPs) through surface radical polymerization to enhance its stability and efficacy in the inflammatory environment of periodontal tissues. The PAAM polymer shell serves as a protective barrier to isolate CAT from interactions with proteolytic enzymes and inflammatory mediators in the periodontal microenvironment, thereby preventing structural denaturation and enhancing enzymatic stability. This approach targets the reduction of ROS levels and the modulation of the Nrf-2/HO-1 antioxidant pathway, key mediators in oxidative stress responses. In vitro and in vivo studies demonstrated that CAT NPs significantly alleviate oxidative stress, reduce pro-inflammatory cytokines, and promote periodontal tissue regeneration. Compared to conventional treatments, CAT NPs exhibit superior therapeutic outcomes, offering a promising and long-lasting solution for the treatment of periodontitis. This innovative strategy provides new avenues for the development of more effective periodontitis therapies.","PeriodicalId":18151,"journal":{"name":"Macromolecular Materials and Engineering","volume":"310 6","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mame.202500022","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144300313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Eucommia Ulmoides Gum Soft-Hard Gradient Composite Materials with Shape Memory Property 具有形状记忆性能的杜仲胶软硬梯度复合材料

IF 4.2 3区材料科学

Macromolecular Materials and Engineering Pub Date : 2025-02-20 DOI: 10.1002/mame.202400440

Furao Wang, Jinjian Lin, Tao Liao, Kexu Bao, Rongzhen Fu, Ruifeng Zhao, Jichuan Zhang

{"title":"Eucommia Ulmoides Gum Soft-Hard Gradient Composite Materials with Shape Memory Property","authors":"Furao Wang, Jinjian Lin, Tao Liao, Kexu Bao, Rongzhen Fu, Ruifeng Zhao, Jichuan Zhang","doi":"10.1002/mame.202400440","DOIUrl":"https://doi.org/10.1002/mame.202400440","url":null,"abstract":"Eucommia Ulmoides gum (EUG) is a natural polymer material with unique “rubber-plastic duality” and good shape memory properties. In this paper, the hardness of EUG is greatly reduced by adjusting the cross-linking density and adding physical microspheres for foaming. The results show that the more sulfur and foamed microspheres are used, the lower the hardness of EUG, the greater the deformation of the material, and the smaller the penetration force. By adjusting the amount of foaming agent, a series of lightweight and high-toughness foamed EUG can be obtained. The EUG, natural rubber (NR) and foamed EUG are prepared into a hardness gradient composite material with a shape memory characteristic through a co-vulcanization process, according to scanning electron microscope (SEM) observation and 180° peel test results, the three rubber materials has good binding force without the help of adhesive. Each unit of thickness of the composite material can reduce the external impact force by up to 11.6%. In addition, under heating conditions, it only takes 30 s for the crystalline EUG to return to its original shape. The prepared soft-hard gradient sports composite material has a high reduction of external impact force per unit thickness, showing an excellent impact protection effect.","PeriodicalId":18151,"journal":{"name":"Macromolecular Materials and Engineering","volume":"310 7","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mame.202400440","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144647551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Scalable Fabrication of Self-Reinforced Bioplastic Composites Using Short Fiber Reinforcements 短纤维增强自增强生物塑料复合材料的可扩展制备

IF 4.2 3区材料科学

Macromolecular Materials and Engineering Pub Date : 2025-02-18 DOI: 10.1002/mame.202500011

Shazed Aziz, John Colwell, Pejman Heidarian, Vincent Mathel, Emilie Gauthier, Tony McNally, Ton Peijs, Russell J. Varley, Peter J. Halley, Luigi-Jules Vandi

{"title":"Scalable Fabrication of Self-Reinforced Bioplastic Composites Using Short Fiber Reinforcements","authors":"Shazed Aziz, John Colwell, Pejman Heidarian, Vincent Mathel, Emilie Gauthier, Tony McNally, Ton Peijs, Russell J. Varley, Peter J. Halley, Luigi-Jules Vandi","doi":"10.1002/mame.202500011","DOIUrl":"https://doi.org/10.1002/mame.202500011","url":null,"abstract":"Bioplastics and biocomposites are eco-friendly alternatives to their petrochemical derived commodity material, but tend to have inferior mechanical and thermal properties. In this work, short-fiber self-reinforced bioplastic composites (SRBCs) have been developed that seek to overcome some of these shortcomings. The SRBCs leverage melt-spun drawn poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) fibers with axially-oriented crystalline structures that exhibit a ≈6.7 °C higher melt temperature than the same PHBV in isotropic form. This enables a controlled-temperature compounding process that preserves the crystalline structure of the fibers without distortion and ensures uniform distribution within the matrix. The resultant composites display a ≈35% increase in ultimate tensile strength and a ≈55% increase in impact resistance compared to neat PHBV polymer. This monolithic-type composite system, characterized by high interfacial compatibility and strong fiber-matrix adhesion, also supports high-value recycling while preserving its mechanical properties across multiple lifecycle uses. By focusing upon discontinuous short fiber reinforcement, this work provides unprecedented opportunities for scaling SRBCs through commodity application pathways such as injection molding, compression molding, and 3D printing.","PeriodicalId":18151,"journal":{"name":"Macromolecular Materials and Engineering","volume":"310 6","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mame.202500011","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144300249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cerium Oxide Decorated Graphene Nanolayers Filled Polyvinylidene Fluoride Nanofibers as Optical Piezoelectric Sensors 作为光学压电传感器的氧化铈装饰石墨烯纳米层填充聚偏氟乙烯纳米纤维

IF 4.2 3区材料科学

Macromolecular Materials and Engineering Pub Date : 2025-02-18 DOI: 10.1002/mame.202400350

Nour Bader, Swathi Yempally, Firas Al-Ashker, Maryam Al-Ejji, Deepalekshmi Ponnamma

{"title":"Cerium Oxide Decorated Graphene Nanolayers Filled Polyvinylidene Fluoride Nanofibers as Optical Piezoelectric Sensors","authors":"Nour Bader, Swathi Yempally, Firas Al-Ashker, Maryam Al-Ejji, Deepalekshmi Ponnamma","doi":"10.1002/mame.202400350","DOIUrl":"https://doi.org/10.1002/mame.202400350","url":null,"abstract":"This article introduces the fabrication of optical piezoelectric sensors using cerium oxide (CeO)-decorated graphene nanolayers incorporated into polyvinylidene fluoride hexafluoropropylene (PVDF-HFP) fibers. Electrospinning method is employed to create the composite nanofibers, resulting in a highly aligned and consistent fibrous structure. Graphene nanolayers are functionalized onto CeO nanoparticles using a rapid and scalable solution-based process. The resulting hybrid composite material exhibited superior piezoelectric characteristics compared to pure PVDF-HFP. A fiber Bragg grating sensor is integrated into the PVDF-HFP nanofiber composite to enable optical sensing. As a strain gauge, the sensor detected variations in fiber length caused by mechanical deformation. The addition of CeO-decorated graphene nanolayers enhanced the piezoelectric response of the PVDF-HFP nanofibers, producing an electrical signal proportional to the applied mechanical stress. The sensor's performance is evaluated under various mechanical stimuli, including compression, bending, and vibration. The sensor demonstrated excellent sensitivity, repeatability, and fast response times. The proposed optical piezoelectric sensor, based on PVDF-HFP nanofibers filled with CeO-decorated graphene nanolayers, shows great potential for applications in robotics, wearable electronics, and structural health monitoring. This sensor technology is highly appealing for next-generation smart materials and devices due to its enhanced piezoelectric properties, optical sensing capabilities, and mechanical resilience.","PeriodicalId":18151,"journal":{"name":"Macromolecular Materials and Engineering","volume":"310 4","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mame.202400350","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143831122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Injectable PEG/Diacerein-Based Anti-Inflammatory Hydrogel for Promoting Cartilage Regeneration: An In Vivo Study 一种可注射的聚乙二醇/二乙胺基抗炎水凝胶促进软骨再生：体内研究

IF 4.2 3区材料科学

Macromolecular Materials and Engineering Pub Date : 2025-02-17 DOI: 10.1002/mame.202400382

Jing Mi, Linghui Meng, Yutian Wang, Huanyu Zhang, Jing Jin, Jianhao Huang, Jingwei Lu, Pu Ying, Lan Li

{"title":"An Injectable PEG/Diacerein-Based Anti-Inflammatory Hydrogel for Promoting Cartilage Regeneration: An In Vivo Study","authors":"Jing Mi, Linghui Meng, Yutian Wang, Huanyu Zhang, Jing Jin, Jianhao Huang, Jingwei Lu, Pu Ying, Lan Li","doi":"10.1002/mame.202400382","DOIUrl":"https://doi.org/10.1002/mame.202400382","url":null,"abstract":"Cartilage defects are common joint disorders that, if left untreated, may progress to severe degenerative joint conditions. Inflammatory response plays a critical role in the pathogenesis of cartilage damage. Hydrogels incorporating diacerein, an anti-inflammatory drug used in clinical settings, can mitigate inflammation that impairs cartilage repair. It is hypothesized that the direct injection of a hydrogel scaffold combining diacerein and polydopamine into cartilage defect sites can enhance localized treatment, reduce surgical risks, and expedite recovery. Therefore, in this study, a hydrogel infused with diacerein is developed to investigate its efficacy for cartilage restoration. By crosslinking poly(ethylene glycol) diacrylate, four-arm polyethylene glycol-functionalized diacerein, hyaluronic acid, and polydopamine, an injectable hydrogel with superior properties is achieved. In vitro evaluations confirm the mechanical strength and biocompatibility of the hydrogel, and in vivo studies demonstrate its effectiveness in cartilage repair and anti-inflammatory activity in a rat model. These findings indicate that hydrogels are promising materials for addressing cartilage defects and advancing tissue engineering and biological implantation strategies.","PeriodicalId":18151,"journal":{"name":"Macromolecular Materials and Engineering","volume":"310 5","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mame.202400382","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144074393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bio-Based Epoxy Resins Derived from Eugenol with High Glass Transition Temperatures as Substitutes for DGEBA 高玻璃化转变温度的丁香酚生物基环氧树脂作为DGEBA的替代品

IF 4.2 3区材料科学

Macromolecular Materials and Engineering Pub Date : 2025-02-14 DOI: 10.1002/mame.202400394

Elisabeth Schamel, Florian Bauer, Herbert Schlachter, Gerd Wehnert, Dominik Söthje

{"title":"Bio-Based Epoxy Resins Derived from Eugenol with High Glass Transition Temperatures as Substitutes for DGEBA","authors":"Elisabeth Schamel, Florian Bauer, Herbert Schlachter, Gerd Wehnert, Dominik Söthje","doi":"10.1002/mame.202400394","DOIUrl":"https://doi.org/10.1002/mame.202400394","url":null,"abstract":"Epoxy resins (EPs) are crucial for high-performance applications like lightweight materials, due to their excellent properties. However, the commonly used diglycidyl ether of bisphenol A (DGEBA) has two major disadvantages: it is synthesized mainly from petrochemicals and includes the health concerning bisphenol A. Eugenol is a bio-based aromatic compound that can be modified into di- or triglycidyl ether. Through investigations four monomers are obtained based on eugenol and crosslinked with two curing agents isophorone diamine and 4,4′-diaminodiphenyl sulfone to compare the properties of the resulting EPs with references containing DGEBA. Using new synthesis routes, the bio-content of the monomers can be increased up to 94 wt%. Intramolecular cyclization occurs if a hydroxy group is in ortho-position to the glycidyl ether group. The crosslinking conditions of the bio-based monomers are comparable to or lower than those of DGEBA. The eugenol-based triglycidyl monomers exhibit very high glass transition temperatures of up to 271 °C, almost 50 °C above the reference value, which can enable their use for lightweight construction such as matrices for fiber-reinforced plastics. The char content of all bio-based EPs after pyrolysis is significantly higher in comparison to the references, which may have a favorable effect on fire resistance.","PeriodicalId":18151,"journal":{"name":"Macromolecular Materials and Engineering","volume":"310 5","pages":""},"PeriodicalIF":4.2,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mame.202400394","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144074245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

CO2-Responsive Copolymers for Membrane Applications, Synthesis, and Performance Evaluation 二氧化碳响应共聚物在膜上的应用、合成和性能评价

IF 4.2 3区材料科学

Macromolecular Materials and Engineering Pub Date : 2025-02-14 DOI: 10.1002/mame.202570006

Emil Pashayev, Prokopios Georgopanos

引用次数: 0

Development and Evaluation of Poly(Lactic-Co-Glycolic Acid) Encapsulated Betulinic Acid Nanocarrier for Improved Anti-Tumor Efficacy 聚乳酸-羟基乙酸包封白桦酸纳米载体的研制及抗肿瘤效果评价

IF 4.2 3区材料科学

Macromolecular Materials and Engineering Pub Date : 2025-02-14 DOI: 10.1002/mame.202570004

Cyril Tlou Selepe, Khanyisile Sheer Dhlamini, Lesego Tshweu, Lusisizwe Kwezi, Bathabile Ramalapa, Suprakas Sinha Ray

引用次数: 0