Macromolecular Materials and Engineering最新文献_第10页

In Vitro Neuroprotective Effect Evaluation of Donepezil-Loaded PLGA Nanoparticles-Embedded PVA/PEG Nanofibers on SH-SY5Y Cells and AP-APP Plasmid Related Alzheimer Cell Line Model 多奈哌齐负载PLGA纳米颗粒-包埋PVA/PEG纳米纤维对SH-SY5Y细胞和AP-APP质粒相关阿尔茨海默氏细胞系模型的体外神经保护作用评价

IF 4.2 3区材料科学

Macromolecular Materials and Engineering Pub Date : 2024-10-24 DOI: 10.1002/mame.202400160

Ece Guler, Humeyra Betul Yekeler, Burcu Uner, Murat Dogan, Asima Asghar, Fakhera Ikram, Yusufhan Yazir, Oguzhan Gunduz, Deepak M Kalaskar, Muhammet Emin Cam

{"title":"In Vitro Neuroprotective Effect Evaluation of Donepezil-Loaded PLGA Nanoparticles-Embedded PVA/PEG Nanofibers on SH-SY5Y Cells and AP-APP Plasmid Related Alzheimer Cell Line Model","authors":"Ece Guler, Humeyra Betul Yekeler, Burcu Uner, Murat Dogan, Asima Asghar, Fakhera Ikram, Yusufhan Yazir, Oguzhan Gunduz, Deepak M Kalaskar, Muhammet Emin Cam","doi":"10.1002/mame.202400160","DOIUrl":"https://doi.org/10.1002/mame.202400160","url":null,"abstract":"Recently developed nanoparticles and nanofibers present new brain-specific treatment strategies, especially for Alzheimer's disease treatment. In this study, donepezil (DO)-loaded PLGA nanoparticles (DNP) are embedded in PVA/PEG nanofibers (DNPF) produced by pressurized gyration for sublingual administration. SEM images showed produced drug-loaded and pure nanofibers, which have sizes between 978 and 1123 nm, demonstrated beadless morphology and homogeneous distribution. FT-IR, XRD, and DSC results proved the produced nanoparticles and fibers to consist of the DO and other polymers. The in vitro drug release test presented that the release profile of DO is completed at the end of the 18th day. It is released by the first order kinetic model. DNPF has an ultra-fast release profile via its disintegration within 2 sec, which proved itself to be suitable for the administration sublingually. All samples presented above ≈90% cell viability via their non-toxic natures on SH-SY5Y human neuroblastoma cells by using Alamar blue assay. The anti-Alzheimer effects of DO, DNP, and DNPF are evaluated on the Aβ1−42-induced SH-SY5Y cells at 1, 5, and 10 µM as treatment groups. The 1 µM dosage exhibited the most significant neuroprotective effects, which showed enhanced cellular uptake and superior modulation of Alzheimer's-related proteins, including tau and Aβ.","PeriodicalId":18151,"journal":{"name":"Macromolecular Materials and Engineering","volume":"310 3","pages":""},"PeriodicalIF":4.2,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mame.202400160","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143602782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adhesive Properties of Eco-Friendly Hot Melt Adhesive Based on Poly(butylene adipate-co-terephthalate) and Rosin Maleic Resin 基于聚己二酸丁二醇酯和马来酸松香树脂的环保型热熔胶的粘合性能

IF 4.2 3区材料科学

Macromolecular Materials and Engineering Pub Date : 2024-10-24 DOI: 10.1002/mame.202400103

Ji-Hyun Cho, Kwang-Hyun Ryu, Hyun-Joong Kim

{"title":"Adhesive Properties of Eco-Friendly Hot Melt Adhesive Based on Poly(butylene adipate-co-terephthalate) and Rosin Maleic Resin","authors":"Ji-Hyun Cho, Kwang-Hyun Ryu, Hyun-Joong Kim","doi":"10.1002/mame.202400103","DOIUrl":"https://doi.org/10.1002/mame.202400103","url":null,"abstract":"As environmental problems increase, disposable products are being replaced and recommended with materials with a low environmental load when it discarded. So the demand for bioplastics for building a sustainable society is increasing. This study focuses mainly on the applicability of biodegradable plastics and rosin maleic resin (RMR, DX-250) blends with potential use in eco-friendly hot-melt adhesives (HMA). Poly (butylene adipate-co-terephthalate) (PBAT), which has high dimensional stability owing to low crystallinity, is used as the main polymer of the HMA. And rosin maleic resin, which is effective for increasing adhesive properties and compatibility as a tackifier. The HMA based on PBAT and RMR blends are prepared via melt-blend extrusion. Compatibility and wettability are increased under the influence of RMR, and adhesion properties are improved, compared to that of PBAT. In addition, as confirmed polarizing microscope (POM), the addition of RMR leads to a decrease in crystallinity, which can be expected to be effective for biodegradation. This result PBAT/RMR 7/3 blend significantly enhances the adhesion strength of PBAT from 1.8 to 7.3 MPa. Therefore, PBAT with the blends containing 30 wt.% of RMR has considerable potential application in the HMA field.","PeriodicalId":18151,"journal":{"name":"Macromolecular Materials and Engineering","volume":"309 12","pages":""},"PeriodicalIF":4.2,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mame.202400103","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142861959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Optimizing Electron-Beam Photothermal Pyrolysis Parameters for Enhanced Molecular Biodegradability of Polyvinyl Chloride Plastics 优化电子束光热热解参数以提高聚氯乙烯塑料的分子生物降解性

IF 4.2 3区材料科学

Macromolecular Materials and Engineering Pub Date : 2024-10-18 DOI: 10.1002/mame.202400257

Rishika Porandla

{"title":"Optimizing Electron-Beam Photothermal Pyrolysis Parameters for Enhanced Molecular Biodegradability of Polyvinyl Chloride Plastics","authors":"Rishika Porandla","doi":"10.1002/mame.202400257","DOIUrl":"https://doi.org/10.1002/mame.202400257","url":null,"abstract":"Polyvinyl chloride (PVC), a synthetic plastic notable for harmful emissions during deterioration, has potential to be molecularly adjusted by photo-oxidative ultraviolet degradation. This research investigates the influence of electron beam irradiation and near-infrared photothermal treatment utilizing gold nanoparticles to establish the optimized molecular weight and beam time exposure for biodegradable PVC properties while maintaining a minimum tensile strength as measured through the ratio of peak tension force by cross sectional area. PVC powder samples with number-average molecular weights ranging from 20.0 to 90.0 kDa and varying exposure times of a 100 kGy electron beam from 80 to 115 ms are employed for the study. Outcomes from PVC irradiation reveal the optimal parameters for inducing biodegradability in samples: an e-beam exposure duration of 95 ms applied to PVC powder with a sample molecular weight of 20.0 kDa. Analysis of the ratio of number average molecular weight <math>\u0000 <semantics>\u0000 <msub>\u0000 <mi>M</mi>\u0000 <mi>n</mi>\u0000 </msub>\u0000 <annotation>$ {{M}_{mathrm{n}}} $</annotation>\u0000 </semantics></math> and weight average molecular weight <math>\u0000 <semantics>\u0000 <msub>\u0000 <mi>M</mi>\u0000 <mi>w</mi>\u0000 </msub>\u0000 <annotation>$ {{M}_{mathrm{w}}} $</annotation>\u0000 </semantics></math> demonstrates that shorter irradiation durations result in lower molecular weights and molecular weight is directly proportional to Tg and crystallinity. Future work aims to scale up the procedure to industrial applications and investigate the treatment's applicability to a variety of thermoplastics.","PeriodicalId":18151,"journal":{"name":"Macromolecular Materials and Engineering","volume":"310 2","pages":""},"PeriodicalIF":4.2,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mame.202400257","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143404804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

CO2-Responsive Copolymers for Membrane Applications, Synthesis, and Performance Evaluation 二氧化碳响应共聚物在膜上的应用、合成和性能评价

IF 4.2 3区材料科学

Macromolecular Materials and Engineering Pub Date : 2024-10-18 DOI: 10.1002/mame.202400290

Emil Pashayev, Prokopios Georgopanos

{"title":"CO2-Responsive Copolymers for Membrane Applications, Synthesis, and Performance Evaluation","authors":"Emil Pashayev, Prokopios Georgopanos","doi":"10.1002/mame.202400290","DOIUrl":"https://doi.org/10.1002/mame.202400290","url":null,"abstract":"The urgent need to mitigate climate change has spurred research into innovative carbon dioxide (CO2) capture materials. In this study, the design and synthesis of CO2-responsive diblock copolymers, poly (N-[3-(dimethylamino)propyl]-acrylamide)-b-poly(methyl methacrylate) (PDMAPAm-b-PMMA) are focused on via a two-step reversible addition−fragmentation chain-transfer (RAFT) polymerization as well as the application of the synthesized diblock copolymer as a membrane for CO2 capture. The resulting diblock copolymer possesses distinct blocks with varying properties. The poly (N-[3-(dimethylamino)propyl]-acrylamide) (PDMAPAm) block provides CO2-responsive behavior, while the poly(methyl methacrylate) (PMMA) block contributes to mechanical stability. The gas transport properties of the fabricated thin-film composite membrane made of PDMAPAm-b-PMMA are measured. It is determined that the copolymer exhibits dual responsiveness towards CO2 and can be tailored for use in fabrication of membranes for direct air capture (DAC).","PeriodicalId":18151,"journal":{"name":"Macromolecular Materials and Engineering","volume":"310 2","pages":""},"PeriodicalIF":4.2,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mame.202400290","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143404803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fabricating Biodegradable Tissue Scaffolds Through a New Aggregation Triggered Physical Cross-Linking Strategy of Hydrophilic and Hydrophobic Polymers 通过亲水性和疏水性聚合物的新聚合触发物理交联策略制造生物可降解组织支架

IF 4.2 3区材料科学

Macromolecular Materials and Engineering Pub Date : 2024-10-15 DOI: 10.1002/mame.202470019

Elif Kaga, Sadik Kaga

引用次数: 0

Masthead: Macromol. Mater. Eng. 10/2024 刊头：Macromol.Mater.Eng.10/2024

IF 4.2 3区材料科学

Macromolecular Materials and Engineering Pub Date : 2024-10-15 DOI: 10.1002/mame.202470020

引用次数: 0

Intrinsically Flame-Retardant Polyamide 6 by Anionic Ring-Opening Copolymerization with a Phosphorous-Containing Comonomer 阴离子开环与含磷共聚物共聚的本质阻燃聚酰胺6

IF 4.2 3区材料科学

Macromolecular Materials and Engineering Pub Date : 2024-10-14 DOI: 10.1002/mame.202400253

Carlo Pani, Hagen J. Altmann, Patrick Probst, Iris Elser, Mark Steinmann, Simon König, Philipp Kreis, Lisa Kuske, Dominik Weidich, Anke Gähr, Jonas Groos, Julian Kappler, Janis Musso, Dongren Wang, Michael R. Buchmeiser

{"title":"Intrinsically Flame-Retardant Polyamide 6 by Anionic Ring-Opening Copolymerization with a Phosphorous-Containing Comonomer","authors":"Carlo Pani, Hagen J. Altmann, Patrick Probst, Iris Elser, Mark Steinmann, Simon König, Philipp Kreis, Lisa Kuske, Dominik Weidich, Anke Gähr, Jonas Groos, Julian Kappler, Janis Musso, Dongren Wang, Michael R. Buchmeiser","doi":"10.1002/mame.202400253","DOIUrl":"https://doi.org/10.1002/mame.202400253","url":null,"abstract":"A three-step synthetic route is established for the synthesis of a phosphorus-containing ε-caprolactam derivative, starting from cyclohex-2-enone and diphenylphosphinous chloride, followed by a Beckmann rearrangement. 2D NMR spectroscopy reveals that the phosphorus moiety is selectively localized at the 4-position of the caprolactam ring. Different amounts of the phosphorus-containing comonomer are systematically incorporated into polyamide 6 by anionic ring-opening copolymerization with ε-caprolactam at elevated temperatures. Polymerization reactions are initiated by a latent, CO2 protected N-heterocyclic carbene in the presence of N-acetyl caprolactam and MgCl2. The phosphorus content is determined by inductively-coupled plasma-optical emission spectroscopy (ICP-OES) analysis. Limiting oxygen indices up to 23.5 are found for polymers containing ≈1 wt.-% of phosphorus. The thermal properties of the copolymers are determined and compared to those of polyamide 6.","PeriodicalId":18151,"journal":{"name":"Macromolecular Materials and Engineering","volume":"310 1","pages":""},"PeriodicalIF":4.2,"publicationDate":"2024-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mame.202400253","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143115241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recent Advances in Ionic Liquid-Based Hybrid Materials for Electroactive Soft Actuator Applications 离子液体基混合材料在电活性软执行器中的应用研究进展

IF 4.2 3区材料科学

Macromolecular Materials and Engineering Pub Date : 2024-10-03 DOI: 10.1002/mame.202400279

L.C. Fernandes, D.M. Correia, C.M. Costa, S. Lanceros-Mendez

引用次数: 0

Slot-Die-Printed Electroactive Polymer Actuators with High-Strain Sensitivity for Soft Robotic Applications 柔性机器人高应变灵敏度开槽印刷电活性聚合物作动器

IF 4.2 3区材料科学

Macromolecular Materials and Engineering Pub Date : 2024-10-01 DOI: 10.1002/mame.202400271

Duanhao Lu, Ying Yu, Yuxin Zuo, Yong Lv, Tianyu Zhang, You Li, Zhangfeng Zhao

{"title":"Slot-Die-Printed Electroactive Polymer Actuators with High-Strain Sensitivity for Soft Robotic Applications","authors":"Duanhao Lu, Ying Yu, Yuxin Zuo, Yong Lv, Tianyu Zhang, You Li, Zhangfeng Zhao","doi":"10.1002/mame.202400271","DOIUrl":"https://doi.org/10.1002/mame.202400271","url":null,"abstract":"Ionic electroactive polymer gels are widely employed as actuators in soft robotics due to their ability to undergo rapid mechanical deformation under low-voltage. How to improve the performance of the ionic electroactive polymer actuators is always the focus of research in this field. Optimizing the migration of ions within the actuator is crucial for enhancing the actuation performance. In this regard, this study innovatively introduces slot-die-printing technology to fabricate gel actuation layers characterized by high smoothness and uniform particle distribution, achieving seamless integration between the electrodes and gel actuation layers, while mitigating issues associated with ion accumulation due to polymer clustering. Furthermore, this study attempts to add lactic acid to the traditional CS-PVA-IL gel, effectively strengthening the connection between CS and PVA, and promoting smooth ion transport within the gel. The results demonstrate that the actuators prepared in this study achieved a high-bending-strain of 0.35%, with a retention rate of 91% for actuation displacement after 10 000 cycles, showcasing superior actuation performance compared to existing research. The fabrication method proposed in this study is simple and highly reproducible, making it suitable for widespread industrial application, and providing a new approach for future industrial production of soft robotics.","PeriodicalId":18151,"journal":{"name":"Macromolecular Materials and Engineering","volume":"310 3","pages":""},"PeriodicalIF":4.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mame.202400271","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143602482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Viscoelastic Properties of Electrospray-Deposited Polymer Shells via Quartz Crystal Microbalance With Dissipation (QCM-D) 石英晶体耗散微天平（QCM-D）研究电喷涂聚合物壳的粘弹性

IF 4.2 3区材料科学

Macromolecular Materials and Engineering Pub Date : 2024-09-30 DOI: 10.1002/mame.202400224

Robert A. Green-Warren, Noah M. McAllister, Parameshwaran Pasupathy, Assimina A. Pelegri, Jonathan P. Singer, N. Sanjeeva Murthy

{"title":"Viscoelastic Properties of Electrospray-Deposited Polymer Shells via Quartz Crystal Microbalance With Dissipation (QCM-D)","authors":"Robert A. Green-Warren, Noah M. McAllister, Parameshwaran Pasupathy, Assimina A. Pelegri, Jonathan P. Singer, N. Sanjeeva Murthy","doi":"10.1002/mame.202400224","DOIUrl":"https://doi.org/10.1002/mame.202400224","url":null,"abstract":"Multilayer polymer films are extensively used in multiphase separation. Electrospray deposition (ESD) is an important technique for fabricating such films with tunable morphology. Viscoelastic properties of polystyrene (PS) nanoshell coatings produced by ESD on gold and spin-coated PS surfaces are evaluated using Quartz Crystal Microbalance with Dissipation (QCM-D). The thickness of PS films on gold increases with flow rate from ∼200 nm at 0.5 to ∼400 nm at 1.5 mL h−1, accompanied by an order-of-magnitude increase in dissipation due to larger particle sizes from shorter droplet flight times. This effect is absent on spin–coated PS films, suggesting the onset of the self-limiting effect of charges. Although the shear moduli for ESD films calculated from Voigt models is only 0.08%–0.20% of the bulk PS modulus, the stiffness ratio of spray-coated PS to a single shell is (5.00–13.3) × 103 m−1, due to shell–shell and shell–substrate interactions. These are novel results related to the interparticle friction obtained using QCM-D for the first time. This work demonstrates that mechanical properties of particulate viscoelastic films with potential applications in high surface area sensors, such as size-selective membranes for protein or electrolyte adsorption, can be evalauted by QCM-D with nanograms of material.","PeriodicalId":18151,"journal":{"name":"Macromolecular Materials and Engineering","volume":"309 12","pages":""},"PeriodicalIF":4.2,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/mame.202400224","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142851520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0