Magnetic Resonance Materials in Physics, Biology and Medicine最新文献

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Free-breathing qRF-MRF with pilot tone respiratory motion navigator for T1, T2, T2*, and off-resonance mapping of the human body at 3 T. 带有先导音呼吸运动导航仪的自由呼吸 qRF-MRF,用于 3 T 下人体的 T1、T2、T2* 和非共振绘图。
IF 2 4区 医学
Magnetic Resonance Materials in Physics, Biology and Medicine Pub Date : 2025-02-01 Epub Date: 2024-10-16 DOI: 10.1007/s10334-024-01209-z
Madison E Kretzler, Sherry S Huang, Jessie E P Sun, Leonardo K Bittencourt, Yong Chen, Mark A Griswold, Rasim Boyacioglu
{"title":"Free-breathing qRF-MRF with pilot tone respiratory motion navigator for T<sub>1</sub>, T<sub>2</sub>, T<sub>2</sub>*, and off-resonance mapping of the human body at 3 T.","authors":"Madison E Kretzler, Sherry S Huang, Jessie E P Sun, Leonardo K Bittencourt, Yong Chen, Mark A Griswold, Rasim Boyacioglu","doi":"10.1007/s10334-024-01209-z","DOIUrl":"10.1007/s10334-024-01209-z","url":null,"abstract":"<p><p>Standard quantitative abdominal MRI techniques are time consuming, require breath-holds, and are susceptible to patient motion artifacts. Magnetic resonance fingerprinting (MRF) is naturally multi-parametric and quantifies multiple tissue properties, including T<sub>1</sub> and T<sub>2</sub>. This work includes T<sub>2</sub>* and off-resonance mapping into a free-breathing MRF framework utilizing a pilot tone navigator. The new acquisition and reconstruction are compared to current clinical standards. Prospective. Ten volunteers. 3 T scanner, Quadratic-RF MRF, Balanced SSFP, Inversion recovery spin-echo, LiverLab. MRI ROIs were evaluated in the liver, spleen, pancreas, kidney (cortex and medulla), and paravertebral muscle by two abdominal imaging investigators for ten healthy adult volunteers for clinical standard, breath-Hold (BH) qRF-MRF, and free-breathing qRF-MRF with pilot-tone (PT) acquisitions. Bland-Altman analysis as well as Student's T tests were used to evaluate and compare the respective ROI analyses. Quantitative values between breath-Hold (BH) and free-breathing qRF-MRF with pilot-tone (PT) results show good agreement with clinical standard T1 and T2 quantitative mapping, and Dixon q-VIBE (acquired using the Siemens LiverLAB). In this work, we show free-breathing abdominal MRF (T<sub>1</sub>, T<sub>2</sub>) with T<sub>2</sub>* results that are quantitatively comparable to current breath-hold MRF and clinical techniques.</p>","PeriodicalId":18067,"journal":{"name":"Magnetic Resonance Materials in Physics, Biology and Medicine","volume":" ","pages":"85-95"},"PeriodicalIF":2.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11973999/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142469070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Signal-to-noise trade-offs between magnet diameter and shield-to-coil distance for cylindrical Halbach-based portable MRI systems for neuroimaging. 用于神经成像的基于哈尔巴赫技术的圆柱形便携式磁共振成像系统在磁体直径和屏蔽线圈间距之间的信噪比权衡。
IF 2 4区 医学
Magnetic Resonance Materials in Physics, Biology and Medicine Pub Date : 2025-02-01 Epub Date: 2024-10-17 DOI: 10.1007/s10334-024-01210-6
Javad Parsa, Andrew Webb
{"title":"Signal-to-noise trade-offs between magnet diameter and shield-to-coil distance for cylindrical Halbach-based portable MRI systems for neuroimaging.","authors":"Javad Parsa, Andrew Webb","doi":"10.1007/s10334-024-01210-6","DOIUrl":"10.1007/s10334-024-01210-6","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the trade-off between magnet bore diameter and the distance between the conductive Faraday shield and RF head coil for low-field point-of-care neuroimaging systems.</p><p><strong>Methods: </strong>Electromagnetic simulations were performed for three different Faraday shield geometries and two commonly used RF coil designs (spiral and solenoid) to assess the effects of a close-fitting shield on the RF coil's transmit and receive efficiencies. Experimental measurements were performed to confirm the accuracy of the simulations. Parallel simulations were performed to assess the static magnet ( <math><msub><mi>B</mi> <mn>0</mn></msub> </math> ) field as a function of the magnet bore diameter. The obtainable SNR was then calculated as a function of these two related variables.</p><p><strong>Results: </strong>Simulations of the RF coil characteristics and <math><msubsup><mi>B</mi> <mrow><mn>1</mn></mrow> <mo>+</mo></msubsup> </math> transmit efficiencies agreed well with corresponding experimentally determined parameters. Overall, the RF coil transmit efficiency was, as expected, higher when the gap between the shield and coil increased. The calculated intrinsic SNR showed that maximum SNR would be obtained for a cylindrical shield of diameter 310 mm with an inner diameter of the magnet of 320 mm (assuming 10 mm for the gradient coils).</p><p><strong>Conclusion: </strong>This work presents an overview of the trade-offs in transmit efficiencies for RF coils used for POC MRI neuroimaging as a function of coil-to-shield distance and inner diameter of the Halbach magnet. Results show that there is a relatively shallow optimum between a magnet diameter of 290 and 330 mm, with values falling more than 10% if either smaller or larger magnets are used.</p>","PeriodicalId":18067,"journal":{"name":"Magnetic Resonance Materials in Physics, Biology and Medicine","volume":" ","pages":"97-105"},"PeriodicalIF":2.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11790726/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142469072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
FeCl3 and GdCl3 solutions as superfast relaxation modifiers for agarose gel: a quantitative analysis. FeCl3和GdCl3溶液作为琼脂糖凝胶的超快速松弛改性剂:定量分析。
IF 2 4区 医学
Magnetic Resonance Materials in Physics, Biology and Medicine Pub Date : 2025-02-01 Epub Date: 2024-12-12 DOI: 10.1007/s10334-024-01216-0
Nur Najihah Hamzaini, Syafia Afifi Ghazali, Ahmad Nazlim Yusoff, Faizah Mohd Zaki, Wan Noor Afzan Wan Sulaiman, Yanurita Dwihapsari
{"title":"FeCl<sub>3</sub> and GdCl<sub>3</sub> solutions as superfast relaxation modifiers for agarose gel: a quantitative analysis.","authors":"Nur Najihah Hamzaini, Syafia Afifi Ghazali, Ahmad Nazlim Yusoff, Faizah Mohd Zaki, Wan Noor Afzan Wan Sulaiman, Yanurita Dwihapsari","doi":"10.1007/s10334-024-01216-0","DOIUrl":"10.1007/s10334-024-01216-0","url":null,"abstract":"<p><strong>Object: </strong>This study aimed to evaluate the relaxivity and uniformity of agarose gel phantoms added with relaxation modifiers. It is hypothesized that the modifiers could manipulate the T1 and T2 relaxations as well as the signal uniformity.</p><p><strong>Materials and methods: </strong>Twenty agarose gel phantoms with different GdCl₃ and FeCl₃ volume fractions were prepared. The phantoms were scanned using a 3-T scanner implementing a turbo spin echo sequence to acquire T1 and T2 images. The SNR of the images were computed using Image-J software from 1, 3, and 25 regions-of-interest (ROIs) and were inverted as T1 and T2 curves.</p><p><strong>Results: </strong>With the increase in relaxation modifier content, T1 SNR increased at a faster rate at very short TR and reached saturation at TR well below 400 ms. Agarose gel phantoms containing GdCl<sub>3</sub> showed a higher saturation value as compared to phantoms containing FeCl<sub>3</sub>. For T2 SNR, differences between plots are observed at low TE. As TE gets larger, the SNR between plots is incomparable. The SNR for both groups was uniform among 1, 3, and 25 ROIs.</p><p><strong>Discussions: </strong>It can be concluded that GdCl₃ and FeCl₃ solutions can be used as effective relaxation modifiers to reduce T1 but not T2 relaxation times.</p>","PeriodicalId":18067,"journal":{"name":"Magnetic Resonance Materials in Physics, Biology and Medicine","volume":" ","pages":"141-160"},"PeriodicalIF":2.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Accelerating multi-coil MR image reconstruction using weak supervision. 利用弱监督加速多线圈磁共振图像重建
IF 2 4区 医学
Magnetic Resonance Materials in Physics, Biology and Medicine Pub Date : 2025-02-01 Epub Date: 2024-10-09 DOI: 10.1007/s10334-024-01206-2
Arda Atalık, Sumit Chopra, Daniel K Sodickson
{"title":"Accelerating multi-coil MR image reconstruction using weak supervision.","authors":"Arda Atalık, Sumit Chopra, Daniel K Sodickson","doi":"10.1007/s10334-024-01206-2","DOIUrl":"10.1007/s10334-024-01206-2","url":null,"abstract":"<p><p>Deep-learning-based MR image reconstruction in settings where large fully sampled dataset collection is infeasible requires methods that effectively use both under-sampled and fully sampled datasets. This paper evaluates a weakly supervised, multi-coil, physics-guided approach to MR image reconstruction, leveraging both dataset types, to improve both the quality and robustness of reconstruction. A physics-guided end-to-end variational network (VarNet) is pretrained in a self-supervised manner using a 4 <math><mo>×</mo></math> under-sampled dataset following the self-supervised learning via data undersampling (SSDU) methodology. The pre-trained weights are transferred to another VarNet, which is fine-tuned using a smaller, fully sampled dataset by optimizing multi-scale structural similarity (MS-SSIM) loss in image space. The proposed methodology is compared with fully self-supervised and fully supervised training. Reconstruction quality improvements in SSIM, PSNR, and NRMSE when abundant training data is available (the high-data regime), and enhanced robustness when training data is scarce (the low-data regime) are demonstrated using weak supervision for knee and brain MR image reconstructions at 8 <math><mo>×</mo></math> and 10 <math><mo>×</mo></math> acceleration, respectively. Multi-coil physics-guided MR image reconstruction using both under-sampled and fully sampled datasets is achievable with transfer learning and fine-tuning. This methodology can provide improved reconstruction quality in the high-data regime and improved robustness in the low-data regime at high acceleration rates.</p>","PeriodicalId":18067,"journal":{"name":"Magnetic Resonance Materials in Physics, Biology and Medicine","volume":" ","pages":"37-51"},"PeriodicalIF":2.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12022963/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142391636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhancing MRI radiomics feature reproducibility and classification performance in Parkinson's disease: a harmonization approach to gray-level discretization variability. 提高帕金森病核磁共振成像放射组学特征的可重复性和分类性能:灰度离散化变异的协调方法。
IF 2 4区 医学
Magnetic Resonance Materials in Physics, Biology and Medicine Pub Date : 2025-02-01 Epub Date: 2024-11-28 DOI: 10.1007/s10334-024-01215-1
Mehdi Panahi, Maliheh Habibi, Mahboube Sadat Hosseini
{"title":"Enhancing MRI radiomics feature reproducibility and classification performance in Parkinson's disease: a harmonization approach to gray-level discretization variability.","authors":"Mehdi Panahi, Maliheh Habibi, Mahboube Sadat Hosseini","doi":"10.1007/s10334-024-01215-1","DOIUrl":"10.1007/s10334-024-01215-1","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to assess the reproducibility of MRI-derived radiomic features across multiple gray-level discretization levels for classifying Parkinson's disease (PD) subtypes, and to evaluate the impact of ComBat harmonization on feature stability and machine learning performance.</p><p><strong>Methods: </strong>T1-weighted MRI scans from 140 PD patients (70 tremor-dominant, 70 postural instability gait difficulty) and 70 healthy controls were obtained from the Parkinson's progression markers initiative (PPMI) database. Radiomic features were extracted from 16 brain regions using 6 discretization levels (8, 16, 32, 64, 128, and 256 bins). ComBat harmonization was applied using a combined batch variable incorporating both scanner models and discretization levels. Intraclass correlation coefficients (ICC) and Kruskal-Wallis tests assessed feature reproducibility before and after harmonization. Support vector machine classifiers were used for PD subtype classification.</p><p><strong>Results: </strong>ComBat harmonization significantly improved feature reproducibility across all feature groups. The percentage of features showing excellent robustness (ICC ≥ 0.90) increased substantially after harmonization. The proportion of features significantly affected by discretization levels was reduced following harmonization. Classification accuracy improved dramatically, from a range of 0.42-0.49 before harmonization to 0.86-0.96 after harmonization across most discretization levels. AUC values similarly increased from 0.60-0.67 to 0.93-0.99 after harmonization.</p><p><strong>Conclusions: </strong>ComBat harmonization significantly enhanced the reproducibility of radiomic features across discretization levels and improved PD subtype classification performance. This study highlights the importance of harmonization in radiomics research for PD and suggests potential clinical applications in personalized treatment planning.</p>","PeriodicalId":18067,"journal":{"name":"Magnetic Resonance Materials in Physics, Biology and Medicine","volume":" ","pages":"23-35"},"PeriodicalIF":2.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142739731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Concentric-object and equiangular-object methods to perform standardized regional analysis in renal mpMRI. 在肾脏 mpMRI 中进行标准化区域分析的同心-目标和等边-目标方法。
IF 2 4区 医学
Magnetic Resonance Materials in Physics, Biology and Medicine Pub Date : 2025-02-01 Epub Date: 2024-10-19 DOI: 10.1007/s10334-024-01208-0
Luis Carlos Sanmiguel-Serpa, Pieter de Visschere, Pim Pullens
{"title":"Concentric-object and equiangular-object methods to perform standardized regional analysis in renal mpMRI.","authors":"Luis Carlos Sanmiguel-Serpa, Pieter de Visschere, Pim Pullens","doi":"10.1007/s10334-024-01208-0","DOIUrl":"10.1007/s10334-024-01208-0","url":null,"abstract":"<p><strong>Objective: </strong>Renal multiparametric magnetic resonance imaging (mpMRI) sequences, including T<sub>1</sub>-T<sub>2</sub> mapping, Blood oxygenation level-dependent (BOLD), Renal blood flow (RBF), and Apparent Diffusion Coefficient (ADC) from diffusion-weighted imaging (DWI), provide insights into kidney function. However, consensus on selecting regions of interest (ROIs) is lacking. This study aims to describe and compare the Concentric Objects (CO) and Equiangular Objects (EO) methods for standardized ROI selection and assess their efficacy in capturing regional variations in renal MRI parameters.</p><p><strong>Materials and methods: </strong>Twelve healthy volunteers underwent mpMRI renal scans. ROIs were selected manually and by applying the CO and EO algorithms to each mpMRI sequence. The methods were tested across various subregion configurations. Regional differences in renal MRI parameters were evaluated.</p><p><strong>Results: </strong>CO and EO methods demonstrated statistically significant differences in mpMRI parameters across renal regions. ASL-RBF, BOLD-MRI, and T<sub>2</sub>-map results indicated substantial variations from the lower to upper kidney areas.</p><p><strong>Discussion: </strong>This study implemented CO and EO algorithms in renal mpMRI, showing their potential for evaluating cortico-medullary and cranio-caudal profiles. The findings validate the CO method for BOLD and ADC measurements and presented ASL-RBF and T<sub>1</sub>-T<sub>2</sub> map profiles. The EO method's utility needs further validation with renal patients.</p>","PeriodicalId":18067,"journal":{"name":"Magnetic Resonance Materials in Physics, Biology and Medicine","volume":" ","pages":"67-83"},"PeriodicalIF":2.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142469069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Design of multi-row parallel-transmit coil arrays for enhanced SAR efficiency with deep brain electrodes at 3T: an electromagnetic simulation study. 设计多排平行发射线圈阵列以提高 3T 下深部脑电极的 SAR 效率:电磁模拟研究。
IF 2 4区 医学
Magnetic Resonance Materials in Physics, Biology and Medicine Pub Date : 2025-02-01 Epub Date: 2024-11-14 DOI: 10.1007/s10334-024-01212-4
Nejat Karadeniz, Joseph V Hajnal, Özlem Ipek
{"title":"Design of multi-row parallel-transmit coil arrays for enhanced SAR efficiency with deep brain electrodes at 3T: an electromagnetic simulation study.","authors":"Nejat Karadeniz, Joseph V Hajnal, Özlem Ipek","doi":"10.1007/s10334-024-01212-4","DOIUrl":"10.1007/s10334-024-01212-4","url":null,"abstract":"<p><strong>Objective: </strong>Tissue heating near the implanted deep brain stimulation (DBS) during magnetic resonance imaging (MRI) poses a significant safety constraint. This study aimed to evaluate the performance of parallel transmit (pTx) head transmit radiofrequency (RF) coils in DBS patients, with a focus on excitation fidelity under specific absorption rate (SAR) control for brain imaging at 3T MRI.</p><p><strong>Materials and methods: </strong>We employed electromagnetic simulations to assess different coil configurations, including multi-row pTx coils of 16-24 channels arranged in 1, 2, and 3 rows, and compared these to a circularly polarised and pTx birdcage coil using a realistic human model without and with DBS leads and electrodes.</p><p><strong>Results: </strong>Two- and three-row pTx coils with overlapping loop elements exhibited similar performance, which was superior in excitation homogeneity and local SAR compared to the single-row coil and the birdcage coil both without and with DBS.</p><p><strong>Discussion: </strong>These findings suggest that multi-row coils can enhance the safety and efficacy of MRI in patients with DBS devices, so potentially improving imaging performance in this expanding patient population. There was a minimal difference in performance between the 2 and 3-row coils, favouring the simpler, lower channel count design for practical implementation.</p>","PeriodicalId":18067,"journal":{"name":"Magnetic Resonance Materials in Physics, Biology and Medicine","volume":" ","pages":"107-120"},"PeriodicalIF":2.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11790791/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142623018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
MRI recovery with self-calibrated denoisers without fully-sampled data. 在没有全采样数据的情况下,使用自校准去噪器进行磁共振成像恢复。
IF 2 4区 医学
Magnetic Resonance Materials in Physics, Biology and Medicine Pub Date : 2025-02-01 Epub Date: 2024-10-16 DOI: 10.1007/s10334-024-01207-1
Muhammad Shafique, Sizhuo Liu, Philip Schniter, Rizwan Ahmad
{"title":"MRI recovery with self-calibrated denoisers without fully-sampled data.","authors":"Muhammad Shafique, Sizhuo Liu, Philip Schniter, Rizwan Ahmad","doi":"10.1007/s10334-024-01207-1","DOIUrl":"10.1007/s10334-024-01207-1","url":null,"abstract":"<p><strong>Objective: </strong>Acquiring fully sampled training data is challenging for many MRI applications. We present a self-supervised image reconstruction method, termed ReSiDe, capable of recovering images solely from undersampled data.</p><p><strong>Materials and methods: </strong>ReSiDe is inspired by plug-and-play (PnP) methods, but unlike traditional PnP approaches that utilize pre-trained denoisers, ReSiDe iteratively trains the denoiser on the image or images that are being reconstructed. We introduce two variations of our method: ReSiDe-S and ReSiDe-M. ReSiDe-S is scan-specific and works with a single set of undersampled measurements, while ReSiDe-M operates on multiple sets of undersampled measurements and provides faster inference. Studies I, II, and III compare ReSiDe-S and ReSiDe-M against other self-supervised or unsupervised methods using data from T1- and T2-weighted brain MRI, MRXCAT digital perfusion phantom, and first-pass cardiac perfusion, respectively.</p><p><strong>Results: </strong>ReSiDe-S and ReSiDe-M outperform other methods in terms of peak signal-to-noise ratio and structural similarity index measure for Studies I and II, and in terms of expert scoring for Study III.</p><p><strong>Discussion: </strong>We present a self-supervised image reconstruction method and validate it in both static and dynamic MRI applications. These developments can benefit MRI applications where the availability of fully sampled training data is limited.</p>","PeriodicalId":18067,"journal":{"name":"Magnetic Resonance Materials in Physics, Biology and Medicine","volume":" ","pages":"53-66"},"PeriodicalIF":2.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11790797/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142469071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A quality assurance protocol for reliable and reproducible multi-TI arterial spin labeling perfusion imaging in rat livers. 可靠和可重复的大鼠肝脏多ti动脉自旋标记灌注成像的质量保证方案。
IF 2 4区 医学
Magnetic Resonance Materials in Physics, Biology and Medicine Pub Date : 2025-01-04 DOI: 10.1007/s10334-024-01223-1
Wan-Ting Zhao, Karl-Heinz Herrmann, Weiwei Wei, Martin Krämer, Uta Dahmen, Jürgen R Reichenbach
{"title":"A quality assurance protocol for reliable and reproducible multi-TI arterial spin labeling perfusion imaging in rat livers.","authors":"Wan-Ting Zhao, Karl-Heinz Herrmann, Weiwei Wei, Martin Krämer, Uta Dahmen, Jürgen R Reichenbach","doi":"10.1007/s10334-024-01223-1","DOIUrl":"https://doi.org/10.1007/s10334-024-01223-1","url":null,"abstract":"<p><strong>Objective: </strong>To establish an arterial spin labeling (ASL) protocol for rat livers that improves data reliability and reproducibility for perfusion quantification.</p><p><strong>Methods: </strong>This study used respiratory-gated, single-slice, FAIR-based ASL imaging with multiple inversion times (TI) in rat livers. Quality assurance measures included: (1) introduction of mechanical ventilation to ensure consistent respiratory cycles by controlling the respiratory rate (45 bpm), tidal volume (10 ml/kg), and inspiration: expiration ratio (I:E ratio, 1:2), (2) optimization of the trigger window for consistent trigger points, and (3) use of fit residual map and coefficient of variance as metrics to assess data quality. We compared image quality, perfusion maps, and fit residual maps between mechanically ventilated and non-ventilated animals, as well as repeated ASL measurements (session = 4 per animal) in two mechanically ventilated animals.</p><p><strong>Results: </strong>Perfusion measurements over multiple sessions in mechanically ventilated rats exhibited low perfusion data variability and high reproducibility both within and between liver lobes. Image quality and perfusion maps were significantly improved in mechanically ventilated animals compared to non-ventilated animals.</p><p><strong>Discussion: </strong>The implementation of mechanical ventilation and optimized quality assurance protocols enhanced the reliability and reproducibility of FAIR-based multi-TI-ASL imaging in rat livers. Our findings demonstrate these measures as a robust approach for achieving consistent liver perfusion quantification in preclinical settings.</p>","PeriodicalId":18067,"journal":{"name":"Magnetic Resonance Materials in Physics, Biology and Medicine","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142927458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of a cost-effective 3D-printed MRI phantom for enhanced teaching of system performance and image quality concepts. 开发具有成本效益的3d打印MRI模型,用于增强系统性能和图像质量概念的教学。
IF 2 4区 医学
Magnetic Resonance Materials in Physics, Biology and Medicine Pub Date : 2024-12-12 DOI: 10.1007/s10334-024-01217-z
Habeeb Yusuff, Pierre-Emmanuel Zorn, Céline Giraudeau, Benoît Wach, Philippe Choquet, Simon Chatelin, Jean-Philippe Dillenseger
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