{"title":"The necessity of prophylactic central lymph node dissection in clinically n0 papillary thyroid carcinoma: perspective from the endemic region.","authors":"Tugba Matlim Ozel, Yigit Soytas, Sezer Akbulut, Aykut Celik, Gorkem Yildiz, Huseyin Karatay, Serkan Sari","doi":"10.1007/s00423-025-03667-y","DOIUrl":"10.1007/s00423-025-03667-y","url":null,"abstract":"<p><strong>Background: </strong>Prophylactic central lymph node dissection (pCND) in papillary thyroid carcinoma (PTC) is still a matter of debate. Therefore, we aimed to identify the factors affecting central lymph node metastasis (CLNM) in patients with clinically node-negative (cN0) PTC.</p><p><strong>Methods: </strong>This retrospective study included 248 patients with cN0 PTC who underwent total thyroidectomy (TT) or TT + pCND. Clinicopathological associations among CLNM, complication rates and the effect of pCND on staging were assessed. Risk factors (RFs) and the pattern of lymph node metastasis (LNM) in PTC patients were studied via multivariate analysis.</p><p><strong>Results: </strong>A total of 216 patients underwent pCND, and 58.8% (127/216) had positive CLNM. Male patients, aged < 41 years, and those with lymphatic invasion were identified as RFs for CLNM, with odds ratios of 2.59, 2.26, and 4.09, respectively. Among the 216 patients, 65 (30%) had transient hypoparathyroidism (HPT), and 20 (9.3%) had permanent HPT. Transient recurrent laryngeal nerve (RLN) palsy occurred in 15 (6.9%) patients, and permanent RLN palsy occurred in 3 (1.4%) patients. Over 55 years of age, 46.7% of patients were upstaged according to the American Joint Committee on Cancer (AJCC) TNM staging system, and 14.2% (n = 18) of the 127 patients with CLNM were upgraded according to the American Thyroid Association (ATA) risk stratification system (RSS).</p><p><strong>Conclusion: </strong>Taken together, in terms of the high incidence rate of CLNM in cN0 PTC patients; We believe that routine pCND, which can be performed with low morbidity rates, is optimal for cN0 PTC patients during their first treatment, especially for those with RFs for CLNM.</p><p><strong>Clinical trials number: </strong>NCT05873283.</p>","PeriodicalId":17983,"journal":{"name":"Langenbeck's Archives of Surgery","volume":"410 1","pages":"109"},"PeriodicalIF":2.1,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11953126/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143735708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Catherine Kollmann, Beata Kusnezov, Lars Kollmann, Jasmin Schmitt, Christoph-Thomas Germer, Johan F Lock, Sven Flemming
{"title":"The effects of endoscopic vacuum therapy for non-operative treatment of anastomotic leakage on oncological outcomes in rectal cancer patients.","authors":"Catherine Kollmann, Beata Kusnezov, Lars Kollmann, Jasmin Schmitt, Christoph-Thomas Germer, Johan F Lock, Sven Flemming","doi":"10.1007/s00423-025-03672-1","DOIUrl":"10.1007/s00423-025-03672-1","url":null,"abstract":"<p><strong>Purpose: </strong>Rectal resection has remained the cornerstone in curative treatment of rectal cancer. This however, implies the risk of anastomotic leakage leading to morbidity, mortality and potentially disease progression. Endoscopic vacuum therapy (EVT) has emerged as a promising tool in leakage therapy in order to avoid reoperation and Hartman resection. However, its clinical efficacy and its potential effect on oncological outcomes still requires further research.</p><p><strong>Methods: </strong>In this retrospective single-centre cohort study, we analysed all consecutive patients undergoing rectal resection for rectal cancer during 2012-2021. The incidence and management of anastomotic leakage and its effects on long-term oncological outcomes were analysed.</p><p><strong>Results: </strong>A total of 334 patients underwent rectal resection of whom 47 patients (14.1%) developed postoperative anastomotic leakage. Non-operative leakage treatment (NOLT) was successful in in 76.9% of which EVT was the most efficient (90.0% success) while reoperation was successful in 52.4% (p = 0.073). The more frequent application of EVT increased the NOLT rate from 48.3 to 66.7% during the observation period (p = 0.176). Concerning long-term outcomes, no differences in disease-free survival (p = 0.657) nor patient survival (p = 0.295) could be determined.</p><p><strong>Conclusion: </strong>EVT is an effective treatment option for anastomotic leakage after rectal resection. EVT enables NOLT in the majority of cases. However, there might be no impact on oncological outcomes.</p>","PeriodicalId":17983,"journal":{"name":"Langenbeck's Archives of Surgery","volume":"410 1","pages":"107"},"PeriodicalIF":2.1,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11950071/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143720059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M Meir, A Wiegering, F Sperschneider, A Hendricks, J F Lock, S Flemming, M Kelm, S Hahner, N Schlegel, C T Germer, J Reibetanz
{"title":"Laparoscopic vs. Robotic transabdominal adrenalectomy- propensity matched analysis and learning curve.","authors":"M Meir, A Wiegering, F Sperschneider, A Hendricks, J F Lock, S Flemming, M Kelm, S Hahner, N Schlegel, C T Germer, J Reibetanz","doi":"10.1007/s00423-025-03688-7","DOIUrl":"10.1007/s00423-025-03688-7","url":null,"abstract":"<p><strong>Background: </strong>While laparoscopic transabdominal or retroperitoneal adrenalectomy is standard care for adrenal tumors, benefits of robotic adrenalectomy (RA) are yet unclear. We evaluated the costs (including disposables), outcomes as well as the learning curve of robotic and laparoscopic adrenalectomy (LA) in a specialized center.</p><p><strong>Methods: </strong>In retrospective analysis of our prospective database (ethical approval number 88/11) 263 LA were compared to 27 RA in the study period between 2018 and 2023. A propensity score match analysis was used to exclude possible confounders. Furthermore, the learning curve of RA was investigated.</p><p><strong>Results: </strong>Intraoperative Riva Rocci (RR) fluctuations (> 160mmHg, < 90 mmHg), early complications (within 30 days) and intraoperative blood loss were comparable in both groups. However, length of stay was decreased following robotic adrenalectomy (3.50d ± 1.81d compared to 4.61d ± 2.75d; p = 0.04). Due to this, overall costs of RA were lower compared to LA even if cost for disposables were slightly higher in the robotic group. An analysis of the learning curve of robotic adrenalectomy revealed that learning curve is completed after 5- 6th procedure.</p><p><strong>Conclusions: </strong>Taken together our study supports the fact that RA is as secure and feasible as LA. Furthermore, it might provide advantages due to shorter length of stay, a short learning curve and similar costs compared to LA.</p>","PeriodicalId":17983,"journal":{"name":"Langenbeck's Archives of Surgery","volume":"410 1","pages":"108"},"PeriodicalIF":2.1,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11950101/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143720006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jamy Vienet, Ismail Labgaa, Rafael Duran, Sébastien Godat, Catherine Blanc, Emilie Uldry, Emmanuel Melloul, David Fuks, Gaëtan-Romain Joliat
{"title":"Incidence and risk factors of biliary leaks after partial hepatectomy within an enhanced recovery perioperative pathway: a single-center retrospective cohort study.","authors":"Jamy Vienet, Ismail Labgaa, Rafael Duran, Sébastien Godat, Catherine Blanc, Emilie Uldry, Emmanuel Melloul, David Fuks, Gaëtan-Romain Joliat","doi":"10.1007/s00423-025-03677-w","DOIUrl":"10.1007/s00423-025-03677-w","url":null,"abstract":"<p><strong>Purpose: </strong>Biliary leak is a specific and frequent complication after hepatectomy. This study aimed to assess the incidence and risk factors of biliary leak after hepatectomy.</p><p><strong>Methods: </strong>A retrospective cohort study was performed. All consecutive patients who underwent hepatectomy between January 2013 and June 2022 were included. Abdominal drainage was performed in case of biliary anastomosis or major hepatectomy. Biliary leak was defined and classified according to the International Study Group for Liver Surgery definition with grades A, B, C based on the required management. Logistic binary regression was used to find risk factors.</p><p><strong>Results: </strong>Data were collected from 565 patients who underwent hepatectomy during the study period. Biliary leaks occurred in 10% (55/565) of patients. The rates of biliary leak grades A, B, and C were 18% (10/55), 37% (20/55), and 45% (25/55), respectively. A high nutrition risk screening (OR 2.1, 95% CI 1.3-3.4), preoperative biliary drainage (OR 4.6, 95% CI 1.5-13.5), and intraoperative biliary anastomosis (OR 3.4, 95% CI 1.3-8.9) were found as independent risk factors for biliary leak on multivariable analysis. In terms of morbidity, biliary leak patients had more infectious complications (46% vs. 8%, p < 0.001) and a longer median hospital stay (26 vs. 7 days, p < 0.001). Regarding treatment, 41 (75%) patients with biliary leak underwent drainage either endoscopically or percutaneously.</p><p><strong>Conclusion: </strong>Preoperative biliary drainage, high nutrition risk screening, and intraoperative biliary anastomosis were independent predictive factors for postoperative biliary leaks. Most frequent treatments of biliary leaks after hepatectomy were antibiotics and drainage.</p>","PeriodicalId":17983,"journal":{"name":"Langenbeck's Archives of Surgery","volume":"410 1","pages":"104"},"PeriodicalIF":2.1,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11937051/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143710512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Osteosarcopenia as a Predictor of Histopathologic Response to Neoadjuvant Chemoradiotherapy in Esophageal Cancer: a Retrospective Cohort Study.","authors":"Yuki Hirase, Ken Sasaki, Yusuke Tsuruda, Masataka Shimonosono, Yasuto Uchikado, Daisuke Matsushita, Takaaki Arigami, Nobuhiro Tada, Kenji Baba, Yota Kawasaki, Takao Ohtsuka","doi":"10.1007/s00423-025-03687-8","DOIUrl":"10.1007/s00423-025-03687-8","url":null,"abstract":"<p><strong>Purpose: </strong>Predicting chemoradiotherapy (CRT) response in esophageal cancer is essential as outcomes vary among patients. This study aimed to evaluate the impact of osteosarcopenia on the effectiveness of neoadjuvant CRT (NACRT).</p><p><strong>Methods: </strong>Ninety-five patients with advanced esophageal cancer who underwent surgical resection post-NACRT were included. Sarcopenia and osteopenia were determined using pre-NACRT skeletal muscle index and bone density at L3 and Th11 levels. Patients were categorized based on osteosarcopenia status.</p><p><strong>Results: </strong>Thirty-seven patients (39%) had osteosarcopenia. Among tumors, 49 (51.6%) were grade 1 (non-responders), 12 (12.6%) were grade 2, and 34 (35.8%) were grade 3 (responders). NACRT was significantly more effective in patients with above-median body mass index, shallow tumor depth, low squamous cell carcinoma antigen levels, and without osteosarcopenia. Osteosarcopenia was independently correlated with the histopathologic response to NACRT. No significant differences in overall or relapse-free survival were observed based on osteosarcopenia status.</p><p><strong>Conclusion: </strong>Osteosarcopenia may predict NACRT response in esophageal cancer.</p>","PeriodicalId":17983,"journal":{"name":"Langenbeck's Archives of Surgery","volume":"410 1","pages":"105"},"PeriodicalIF":2.1,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11937212/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143710440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yehuda Kariv, Ronen Berkovitz, Reut El-On, Alexander Barenboim, Hagit Tulchinsky, Meir Zemel, Oded Brautbar, Dan Mirelman, Sharon Pelles-Avraham, Ravit Geva, Inna Ospovat, Guy Lahat, Jonathan B Yuval
{"title":"MRI is more accurate than FDG-PET in assessing complete response in rectal cancer patients after neoadjuvant therapy.","authors":"Yehuda Kariv, Ronen Berkovitz, Reut El-On, Alexander Barenboim, Hagit Tulchinsky, Meir Zemel, Oded Brautbar, Dan Mirelman, Sharon Pelles-Avraham, Ravit Geva, Inna Ospovat, Guy Lahat, Jonathan B Yuval","doi":"10.1007/s00423-025-03679-8","DOIUrl":"10.1007/s00423-025-03679-8","url":null,"abstract":"<p><strong>Purpose: </strong>The role of FDG-PET in the restaging rectal cancer following neoadjuvant therapy (NAT) is not clear. We compared the accuracy of FDG-PET and MRI in the assessment of rectal cancer response to NAT.</p><p><strong>Methods: </strong>Data of patients treated between January 2015 and September 2022 were captured from a rectal tumor registry. Restaging FDG-PET and MRI were evaluated for the presence of viable tumor. Imaging was compared to the reference standard of pathological results for patients that underwent surgery, and sustained clinical complete response for patients that entered watch and wait. Sensitivity was defined as correctly identifying patients with a complete response.</p><p><strong>Results: </strong>Eighty-two patients met the inclusion criteria. Of these, 60 patients underwent restaging MRI and 54 underwent restaging FDG-PET. Thirty-two were evaluated by both modalities. Mean age and distance from anal verge were 59.9 ± 12.7 years and 5.9 ± 3.2 cm. Baseline staging was cT1-2, cT3 and cT4 for 7 (8.5%), 62 (75.6%) and 13 (15.9%) of the patients, respectively. Baseline nodal staging was cN0 and cN + for 32 (39%) and 50 (61%) of the patients, respectively. All patients were treated with radiation with the majority 73 (89%) receiving chemoradiotherapy. There were 17 patients (21%) that had a pathological or sustained clinical complete response. All baseline characteristics were not meaningfully different between groups. MRI was more accurate than FDG-PET in all parameters including sensitivity, specificity, positive and negative predictive value and overall accuracy.</p><p><strong>Conclusion: </strong>MRI outperforms FDG-PET in the identification of complete response in rectal cancer patients after NAT.</p>","PeriodicalId":17983,"journal":{"name":"Langenbeck's Archives of Surgery","volume":"410 1","pages":"106"},"PeriodicalIF":2.1,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11937214/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143710521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mateusz Wityk, Michał R Janik, Maciej Bobowicz, Natalia Dowgiałło-Gornowicz
{"title":"The usefulness of fluorescence in decision-making strategy during bariatric and metabolic surgery.","authors":"Mateusz Wityk, Michał R Janik, Maciej Bobowicz, Natalia Dowgiałło-Gornowicz","doi":"10.1007/s00423-025-03683-y","DOIUrl":"10.1007/s00423-025-03683-y","url":null,"abstract":"<p><strong>Purpose: </strong>Fluorescence is used in various surgical fields to detect tissue ischemia. However, its use in obesity surgery is still limited. This study aims to investigate whether fluorescence can change surgical decisions during metabolic and bariatric surgery. The primary objective was to determine the proportion of patients with abnormal blood flow assessed by fluorescence and changes in intraoperative strategy. The second outcome measured was the morbidity and mortality within 30 days.</p><p><strong>Methods: </strong>This single-centre, prospective observational study analysed patients who underwent primary metabolic and bariatric surgery. Data was collected from 66 consecutive patients who qualified for primary one anastomosis gastric bypass and Roux-en-Y gastric bypass procedures.</p><p><strong>Results: </strong>In total, improper blood supply was observed in two cases, and surgical strategy was changed in 5.8% of OAGB and 2% of RYGB. No leakage incidents were reported. One patient (1.5%) experienced non-ischemic-related complications. No mortality was observed 30 days after the surgical procedures. No complications related to ICG administration were observed.</p><p><strong>Conclusion: </strong>Despite the low incidence of tissue ischemia during metabolic and bariatric surgery, adding ICG fluorescence may potentially impact intraoperative surgical decisions due to ischemia detection during metabolic and bariatric surgery. However, this field lacks systematic data, and further research with a larger patient group is necessary to establish conclusive evidence.</p>","PeriodicalId":17983,"journal":{"name":"Langenbeck's Archives of Surgery","volume":"410 1","pages":"103"},"PeriodicalIF":2.1,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11933117/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143700789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reflections on the role of diaphragmatic resection techniques in cytoreductive surgery: indications, outcomes, and unresolved questions.","authors":"Juan José Segura-Sampedro, Andrea Craus-Miguel","doi":"10.1007/s00423-025-03646-3","DOIUrl":"10.1007/s00423-025-03646-3","url":null,"abstract":"","PeriodicalId":17983,"journal":{"name":"Langenbeck's Archives of Surgery","volume":"410 1","pages":"102"},"PeriodicalIF":2.1,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11929730/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143692691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Performance and safety of Kangduo surgical robot versus da Vinci robotic system for urologic surgeries.","authors":"Yanan Liu, Fengjiao Wang, Xuexin Li","doi":"10.1007/s00423-025-03670-3","DOIUrl":"10.1007/s00423-025-03670-3","url":null,"abstract":"<p><strong>Objective: </strong>Kangduo (KD) surgical robot is a novel robotic system in China, and some animal experiments and single-arm clinical trials have indicated its effectiveness, feasibility, and safety for urologic surgeries. This study intended to compare the performance and safety of the KD surgical robot with the da Vinci (DV) robotic system in patients who received urologic surgeries.</p><p><strong>Methods: </strong>A total of 201 patients who received urologic surgeries were divided into the KD group (N = 60) and the DV group (N = 141) according to the actual surgical methods.</p><p><strong>Results: </strong>The median (range) operation time [180.0 (30.0-540.0) minutes vs. 130.0 (70.0-360.0) minutes] (P < 0.001) and indwelling time of abdominal drainage tube [5.0 (2.0-14.0) days vs. 3.0 (2.0-18.0) days] (P < 0.001) were longer, but the intraoperative blood loss [50.0 (10.0-200.0) mL vs. 50.0 (10.0-400.0) mL] (P < 0.001) was less in the KD group than the DV group. The median values of white blood cells at the 1st (P = 0.032) and 3rd (P = 0.022) day after surgery were decreased in the KD group compared to the DV group. The incidence of infection (11.7% vs. 29.1%) (P = 0.008) and fever (15.0% vs. 30.5%) (P = 0.023) was lower in the KD group compared to the DV group. Postoperative and follow-up parameters, including time of urinary incontinence improvement, administration of hemostatic, pain numeric rating scale score, Barthel's index score, and patient satisfaction, were not different between the two groups (all P > 0.05).</p><p><strong>Conclusion: </strong>The KD surgical robot unveils satisfactory surgical performance compared to the DV robotic system in patients receiving urologic surgeries.</p>","PeriodicalId":17983,"journal":{"name":"Langenbeck's Archives of Surgery","volume":"410 1","pages":"100"},"PeriodicalIF":2.1,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11919935/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143657640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diletta Corallino, Andrea Balla, Diego Coletta, Daniela Pacella, Mauro Podda, Annamaria Pronio, Monica Ortenzi, Francesca Ratti, Salvador Morales-Conde, Pierpaolo Sileri, Luca Aldrighetti
{"title":"Systematic review on the use of artificial intelligence to identify anatomical structures during laparoscopic cholecystectomy: a tool towards the future.","authors":"Diletta Corallino, Andrea Balla, Diego Coletta, Daniela Pacella, Mauro Podda, Annamaria Pronio, Monica Ortenzi, Francesca Ratti, Salvador Morales-Conde, Pierpaolo Sileri, Luca Aldrighetti","doi":"10.1007/s00423-025-03651-6","DOIUrl":"10.1007/s00423-025-03651-6","url":null,"abstract":"<p><strong>Purpose: </strong>Bile duct injury (BDI) during laparoscopic cholecystectomy (LC) is a dreaded complication. Artificial intelligence (AI) has recently been introduced in surgery. This systematic review aims to investigate whether AI can guide surgeons in identifying anatomical structures to facilitate safer dissection during LC.</p><p><strong>Methods: </strong>Following PROSPERO registration CRD-42023478754, a Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA)-compliant systematic search of MEDLINE (via PubMed), EMBASE, and Web of Science databases was conducted.</p><p><strong>Results: </strong>Out of 2304 articles identified, twenty-five were included in the analysis. The mean average precision for biliary structures detection reported in the included studies reaches 98%. The mean intersection over union ranges from 0.5 to 0.7, and the mean Dice/F1 spatial correlation index was greater than 0.7/1. AI system provided a change in the annotations in 27% of the cases, and 70% of these shifts were considered safer changes. The contribution to preventing BDI was reported at 3.65/4.</p><p><strong>Conclusions: </strong>Although studies on the use of AI during LC are few and very heterogeneous, AI has the potential to identify anatomical structures, thereby guiding surgeons towards safer LC procedures.</p>","PeriodicalId":17983,"journal":{"name":"Langenbeck's Archives of Surgery","volume":"410 1","pages":"101"},"PeriodicalIF":2.1,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11919950/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143657641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}