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International Society of Laser Proctology Position Paper on SiLaC and EPSiT/SiLaC in the Management of Pilonidal Sinus Disease. 国际激光直肠学会关于SiLaC和EPSiT/SiLaC在毛窦疾病治疗中的立场文件。
IF 1.9 3区 医学
Lasers in Surgery and Medicine Pub Date : 2025-10-13 DOI: 10.1002/lsm.70071
Mustapha Ouali, Gonzalo P Martin-Martin, Salih Avdicausevic, Amine Alam, Pavel Istok, Ints Brunenieks, Vladimir Dobricanin, Vincent de Parades, Jiong Wu, Peter C Ambe
{"title":"International Society of Laser Proctology Position Paper on SiLaC and EPSiT/SiLaC in the Management of Pilonidal Sinus Disease.","authors":"Mustapha Ouali, Gonzalo P Martin-Martin, Salih Avdicausevic, Amine Alam, Pavel Istok, Ints Brunenieks, Vladimir Dobricanin, Vincent de Parades, Jiong Wu, Peter C Ambe","doi":"10.1002/lsm.70071","DOIUrl":"https://doi.org/10.1002/lsm.70071","url":null,"abstract":"<p><strong>Objectives: </strong>Minimally invasive treatment of pilonidal sinus disease (PSD) via sinus tract laser closure (SiLaC) and endoscopic pilonidal sinus treatment (EPSiT) is being increasingly employed to manage PSD. Despite its wide adoption amongst colorectal surgeons in many nations, there still exists a wide heterogeneity in surgical technique. The International Society of Laser Proctology (ISoLP) was created by experts in laser proctology has the goal of improving laser-based interventions in coloproctology with the aim of improving patient care in this specialized area.</p><p><strong>Methods: </strong>This position paper is based on the limited evidence from available literature and largely on the expert opinion of ISoLP members with extended expertise in SiLaC and EPSiT.</p><p><strong>Results: </strong>ISoLP experts in SiLaC and EPSiT procedures have suggested 10 statements to aid in homogenizing the SiLaC procedure alone and in combination with EPSiT, with the goal of improving treatment outcomes.</p><p><strong>Conclusion: </strong>The 10 ISoLP position statements have a potential of shaping and homogenizing laser-assisted management of PSD.</p>","PeriodicalId":17961,"journal":{"name":"Lasers in Surgery and Medicine","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145280533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Subdermal 1064-nm Nd:YAG Laser for the Aesthetic Management of Brachial Ptosis: Blinded Clinical Evaluation in 24 Upper Limbs. 1064 nm Nd:YAG皮下激光治疗臂膀上睑下垂:24例上肢盲法临床评价。
IF 1.9 3区 医学
Lasers in Surgery and Medicine Pub Date : 2025-10-13 DOI: 10.1002/lsm.70073
Rosanna Rodríguez-Betancourt, Pedro A Martínez-Carpio
{"title":"Subdermal 1064-nm Nd:YAG Laser for the Aesthetic Management of Brachial Ptosis: Blinded Clinical Evaluation in 24 Upper Limbs.","authors":"Rosanna Rodríguez-Betancourt, Pedro A Martínez-Carpio","doi":"10.1002/lsm.70073","DOIUrl":"https://doi.org/10.1002/lsm.70073","url":null,"abstract":"<p><strong>Background and objective: </strong>Subdermal application of Nd:YAG lasers at wavelengths of 1064, 1320, and 1444 nm has shown promise as a minimally invasive treatment for mild to moderate brachial ptosis. This study explores the efficacy and safety of our procedure, using the 1064 nm wavelength as a standalone modality.</p><p><strong>Study design/materials and methods: </strong>This was a single-arm, evaluator-blinded clinical trial. A standardized surgical protocol was implemented using subcutaneous delivery of a pure 1064 nm Nd:YAG laser (SP Dynamis, Fotona, Slovenia). The study included 24 upper limbs from 12 female patients diagnosed with stage 2a or 2b brachial ptosis (El Khatib classification). Standardized anthropometric measurements and photographic documentation were obtained at 35 days, 3 months, and 9 months postprocedure. Safety and efficacy were assessed through clinical evaluations and validated patient-reported outcome measures.</p><p><strong>Results: </strong>Significant esthetic improvements were observed in all treated limbs (p < 0.0001), including reductions in maximum arm circumference (p = 0.0005) and ptosis grade (p = 0.0016) in both arms. The most pronounced changes occurred by Day 35, with additional minor improvements at 3 months that remained stable through the 9-month follow-up. Patient satisfaction was high, and no significant intraoperative or postoperative complications were reported.</p><p><strong>Conclusions: </strong>Subdermal 1064 nm Nd:YAG laser shows a favorable efficacy and safety profile and, if validated in larger studies, could become a first-line option for mild to moderate brachial ptosis.</p>","PeriodicalId":17961,"journal":{"name":"Lasers in Surgery and Medicine","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145280551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Feasibility Study of a Novel Stent-Based Low-Level Laser Therapy Device for Reducing Severe Radiation-Induced Oral Mucositis. 新型支架低水平激光治疗重度放射性口腔黏膜炎的可行性研究。
IF 1.9 3区 医学
Lasers in Surgery and Medicine Pub Date : 2025-10-07 DOI: 10.1002/lsm.70069
Jong Yun Baek, Kyungmi Yang, Tae Hoon Lee, Sung Uk Lee, Sung Ho Moon, In Young Jo, Keun-Yong Eom, Dongryul Oh
{"title":"Feasibility Study of a Novel Stent-Based Low-Level Laser Therapy Device for Reducing Severe Radiation-Induced Oral Mucositis.","authors":"Jong Yun Baek, Kyungmi Yang, Tae Hoon Lee, Sung Uk Lee, Sung Ho Moon, In Young Jo, Keun-Yong Eom, Dongryul Oh","doi":"10.1002/lsm.70069","DOIUrl":"https://doi.org/10.1002/lsm.70069","url":null,"abstract":"<p><strong>Objectives: </strong>Radiation-induced oral mucositis (RIOM) is a severe complication of radiotherapy (RT) for head and neck cancers, impairing quality of life and treatment adherence. Low-level laser therapy (LLLT) shows promise for reducing RIOM severity, but operator-dependent devices limit practicality. This feasibility study assessed the safety and efficacy of a novel intraoral stent-based LLLT device designed for consistent laser delivery.</p><p><strong>Materials and methods: </strong>This prospective, single-arm, multicenter study enrolled 15 patients receiving curative RT for head and neck cancers. The stent-based device delivered laser light to 43 oral cavity points at three wavelengths (670, 830, and 910 nm) during 20-min sessions, five times weekly. The primary end point was the incidence of Grade 3 or higher RIOM (WHO oral mucositis scale). Pain severity was a secondary end point (Numeric Pain Rating Scale [NPRS]).</p><p><strong>Results: </strong>Grade 3 or higher RIOM occurred in 6.6% of patients, significantly lower than historical rates (30%-40%). No patients reported severe pain (NPRS ≥ 8). The device was well-tolerated with no adverse effects, and all patients completed RT as planned.</p><p><strong>Conclusions: </strong>The intraoral stent-based LLLT device is a safe and potentially effective intervention for reducing severe RIOM. Randomized trials are warranted to confirm these findings.</p><p><strong>Trial registration: </strong>This study was a prospective, single-arm feasibility trial and was not registered in a clinical trial registry, as it did not meet the criteria for mandatory registration at the time of its initiation.</p>","PeriodicalId":17961,"journal":{"name":"Lasers in Surgery and Medicine","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145244589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Therapeutic Window of Laser Dosimetry for the Treatment of Knee Osteoarthritis. 激光剂量法治疗膝骨关节炎的治疗窗。
IF 1.9 3区 医学
Lasers in Surgery and Medicine Pub Date : 2025-10-06 DOI: 10.1002/lsm.70072
Yulia Alexandrovskaya, Felix Feldchtein, Andreas Glatz, Anatoly Shekhter, Elizaveta Kon, Valerii Vinokur, Emil Sobol
{"title":"Therapeutic Window of Laser Dosimetry for the Treatment of Knee Osteoarthritis.","authors":"Yulia Alexandrovskaya, Felix Feldchtein, Andreas Glatz, Anatoly Shekhter, Elizaveta Kon, Valerii Vinokur, Emil Sobol","doi":"10.1002/lsm.70072","DOIUrl":"https://doi.org/10.1002/lsm.70072","url":null,"abstract":"<p><strong>Objectives: </strong>We propose a non-destructive laser method that uses controlled thermomechanical action to treat degenerative cartilage changes. The technique aims to reduce pain, offers a minimally invasive option for early- to mid-stage degeneration, and lessens the need for joint replacement.</p><p><strong>Methods: </strong>An ex vivo study on laser treatment of articular cartilage involves theoretical modeling of laser-induced heating, stress relaxation, and cartilage denaturation. Theoretical model simulates the laser treatment of a multilayer system using modulated infrared radiation. It integrates the 3D heat diffusion equation with a thermomechanical model of stress relaxation and micropore formation caused by the rupture of chemical bonds. The risk of tissue denaturation is estimated with Arrhenius model. The model validation involves ex vivo temperature measurements obtained with a thermal imaging camera and experimental histological data from pig joints. This approach helps define the optimal laser dosimetry that encourages cartilage repair without causing overheating or denaturation.</p><p><strong>Results: </strong>Experimental measurements of cartilage temperature and histological structural changes under laser irradiation confirm the model's predictions. The therapeutic window includes a lower limit marking the onset of effective stress relaxation and pore formation, while the upper limit indicates the threshold of tissue overheating and denaturation. Laser irradiation of an articular cartilage with λ = 1470 nm, pulse duration 100 ms, pulse repetition rate 1 Hz, and fiber diameter 0.6 mm shows that the therapeutic window is in the range of 0.5-0.9 W. This therapeutic window is wide enough and depends little on the parameters of cartilage defect being treated or on the conditions of laser radiation delivery for a particular patient.</p><p><strong>Conclusion: </strong>Laser-induced heating and structural changes in cartilage verify theoretical predictions, establishing a safe and effective therapeutic window. These findings support clinical trials of the 1470 nm laser, used alongside arthroscopy, to repair degenerative cartilage and alleviate knee pain.</p>","PeriodicalId":17961,"journal":{"name":"Lasers in Surgery and Medicine","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145238977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exportable Model of a Pro-Bono Laser Tattoo Removal Clinic: Guidelines for Clinicians Seeking to Make an Impact in Their Communities. 公益激光纹身去除诊所的可导出模型:临床医生寻求在其社区中产生影响的指南。
IF 1.9 3区 医学
Lasers in Surgery and Medicine Pub Date : 2025-09-24 DOI: 10.1002/lsm.70066
Eryn Patin, Kathyana P Santiago Mangual, Sepideh Ashrafzadeh, Neha Kinariwalla, Christina Marcelus, Paul M Friedman, Arianne S Kourosh
{"title":"Exportable Model of a Pro-Bono Laser Tattoo Removal Clinic: Guidelines for Clinicians Seeking to Make an Impact in Their Communities.","authors":"Eryn Patin, Kathyana P Santiago Mangual, Sepideh Ashrafzadeh, Neha Kinariwalla, Christina Marcelus, Paul M Friedman, Arianne S Kourosh","doi":"10.1002/lsm.70066","DOIUrl":"https://doi.org/10.1002/lsm.70066","url":null,"abstract":"","PeriodicalId":17961,"journal":{"name":"Lasers in Surgery and Medicine","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145137913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Photochemical Crosslinking as an Adjunct for Repairing Corneal Perforations in Rabbits. 光化学交联修复兔角膜穿孔的研究。
IF 1.9 3区 医学
Lasers in Surgery and Medicine Pub Date : 2025-09-24 DOI: 10.1002/lsm.70068
Honghu Jiang, Lu Zhu, Lanting Yang, Hongyuan Ren, Yan Yu, Jingyin Zhu
{"title":"Photochemical Crosslinking as an Adjunct for Repairing Corneal Perforations in Rabbits.","authors":"Honghu Jiang, Lu Zhu, Lanting Yang, Hongyuan Ren, Yan Yu, Jingyin Zhu","doi":"10.1002/lsm.70068","DOIUrl":"https://doi.org/10.1002/lsm.70068","url":null,"abstract":"<p><strong>Objectives: </strong>To assess the efficacy and tolerability of Rose Bengal-induced photochemical crosslinking (RB-PCL) as an adjunct to suturing for corneal perforation repair in rabbits.</p><p><strong>Methods: </strong>A 4.5 mm corneal wound was created in New Zealand White Rabbits (right eyes), followed by suturing and RB-PCL treatment using 532 nm green light (0.6 W/cm²) and 0.01% RB photosensitizer. A control group received sutures alone. Healing was evaluated at Weeks 1, 2, and 4 using slit-lamp biomicroscopy, anterior segment optical coherence tomography (AS-OCT), RT-PCR for α-SMA gene expression, and immunofluorescence for myofibroblast activation. Histopathological changes were assessed via Hematoxylin and Eosin (H&E) staining, and corneal endothelial cell counts were taken to assess cytotoxicity.</p><p><strong>Results: </strong>RB-PCL accelerated suture removal by Day 5, while sutures in the control group required longer retention. At Weeks 1 and 2, RB-PCL demonstrated lower inflammation and reduced corneal opacity. By Weeks 2 and 4, α-SMA expression was significantly reduced in the RB-PCL group, indicating reduced myofibroblast activation and fibrosis. H&E staining showed complete healing in the RB-PCL group by Week 2, whereas the control group had incomplete repair. By Week 4, the RB-PCL group had better fiber arrangement, while the control group showed persistent fibrosis. Immunofluorescence confirmed reduced α-SMA expression in the RB-PCL group. No retinal damage was observed, and endothelial cell counts were similar between groups, indicating RB-PCL's tolerability.</p><p><strong>Conclusions: </strong>RB-PCL improved corneal wound healing, reduced fibrosis and opacity, and allowed earlier suture removal without phototoxicity. These results suggest RB-PCL is a promising adjunct for corneal perforation repair, enhancing both efficacy and tolerability.</p>","PeriodicalId":17961,"journal":{"name":"Lasers in Surgery and Medicine","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145138011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Femtosecond Laser Ablation Behaviors of Bovine Bone With High Ablation Rate and Low Damage 高烧蚀率、低损伤的牛骨飞秒激光烧蚀行为。
IF 1.9 3区 医学
Lasers in Surgery and Medicine Pub Date : 2025-09-22 DOI: 10.1002/lsm.70065
Daisun Wang, Guohu Luo, Yongxiang Hu, Zijie Lu
{"title":"Femtosecond Laser Ablation Behaviors of Bovine Bone With High Ablation Rate and Low Damage","authors":"Daisun Wang,&nbsp;Guohu Luo,&nbsp;Yongxiang Hu,&nbsp;Zijie Lu","doi":"10.1002/lsm.70065","DOIUrl":"10.1002/lsm.70065","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background and Objective</h3>\u0000 \u0000 <p>The utilization of ultrafast lasers in bone material ablation is of paramount importance in minimally invasive surgical procedures. While ultrafast lasers are precise, achieving high efficiency and low thermal damage in bone ablation remains challenging.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This study investigates the ablation behaviors of bovine bone (storage in water) under different defocus distances using a femtosecond laser under ambient air conditions.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The presence of bone canaliculi on the ablated surface indicates that the microstructure of the bone is well-preserved during laser ablation. The surface morphology and ablation area far beyond the heat-affected zone indicate that mechanical forces, rather than thermal effects from the femtosecond laser, were the primary factor in bone removal. The laser fluence and the overlap rate are pivotal in determining the ablation rate, which can be expressed in terms of cumulative laser fluence. The use of a scanning electron microscope (SEM) and a Raman spectrometer has revealed that no thermal damage occurs during laser ablation when the laser parameters are appropriately adjusted. It has been demonstrated that excessive cumulative laser fluence can result in thermal damage during continuous ablation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The ablation method achieves a rate of 1.2 mm<sup>3</sup>/s with no thermal damage, which is comparable to that of the Er: YAG laser. The study thus establishes a threshold for a process that removes bone material with a high ablation rate and minimal damage, using a femtosecond laser.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17961,"journal":{"name":"Lasers in Surgery and Medicine","volume":"57 9","pages":"735-748"},"PeriodicalIF":1.9,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145124966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immediate Tissue Responses to Multipulse Low Fluence Laser Treatment in a Chorioallantoic Membrane Model of Port Wine Birthmarks 多脉冲低通量激光治疗葡萄酒胎记绒毛膜-尿囊膜模型的即时组织反应。
IF 1.9 3区 医学
Lasers in Surgery and Medicine Pub Date : 2025-09-22 DOI: 10.1002/lsm.70045
Cemre Busra Turk, James Childs, Ilya Yaroslavsky, Gregory Altshuler, R. Rox Anderson, Yakir S. Levin
{"title":"Immediate Tissue Responses to Multipulse Low Fluence Laser Treatment in a Chorioallantoic Membrane Model of Port Wine Birthmarks","authors":"Cemre Busra Turk,&nbsp;James Childs,&nbsp;Ilya Yaroslavsky,&nbsp;Gregory Altshuler,&nbsp;R. Rox Anderson,&nbsp;Yakir S. Levin","doi":"10.1002/lsm.70045","DOIUrl":"10.1002/lsm.70045","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Objectives&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;The standard Port Wine Stains (PWS) treatment involves using single pulse high fluence (SPHF) laser therapy, which often leads to discomfort and requires multiple sessions. According to the Arrhenius theory, employing multiple pulses with low fluence (MPLF) that have lower peak power could potentially reduce pain while still achieving the therapeutic goals. This study aims to explore the potential of MPLF at 530 nm in achieving the desired clinical endpoints in treating PWS. Additionally, it seeks to validate the predictions of the Arrhenius theory regarding thermal denaturation against empirical data, utilizing established kinetic parameters.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Method&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;We evaluated vascular responses to SPHF and MPLF approaches using the chorioallantoic membrane (CAM) model and a 530 nm customized fiber laser. Vascular changes were observed with a digital microscope, and temperature was monitored with a thermal camera during irradiation through a 3 × 3 mm spot at 9–10 ms pulse durations, targeting stable coagulum and vessel collapse. First, we established the SPHF threshold, then applied MPLF at 20%–75% of this fluence with a pulse duration of 9–10 ms and a repetition rate of 0.1 or 0.2 Hz (corresponding to 1 pulse every 10 or 5 s, respectively). Additionally, we used the Arrhenius theory with specific kinetic parameters to predict and validate thermal damage.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Results&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;We observed that both SPHF and MPLF approaches effectively achieved clinical endpoints. Stable coagulum formation was successful at a fluence of 4.2 J/cm² with a pulse width of 10 ms under SPHF. Similarly, MPLF achieved stable coagulum at a lower fluence of 2.2 J/cm², with the thrombus forming after 16 pulses and enlarging by the 32nd pulse. Vessel collapse was also noted at a fluence of 10.8 J/cm² in the SPHF regime and at 5.9 J/cm² with MPLF, with early closure observed after the fourth pulse and completion by the sixteenth. Surface temperature measurements indicated a minor rise following laser exposure, which quickly returned to near baseline levels. Using two sets of activation energies, the Arrhenius model predicted the extent of vessel denaturation and informed the number of pulses required to reach the damage threshold, indicating a lower slope and thus easier damage accumulation with MPLF below the SPHF threshold.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Conclusion&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;This study provides evidence that using MPLF laser treatment at 530 nm with fluences ranging from 50% to 70% of the SPHF threshold can effectively induce stable coagulum and vessel collapse within the CAM","PeriodicalId":17961,"journal":{"name":"Lasers in Surgery and Medicine","volume":"57 9","pages":"726-734"},"PeriodicalIF":1.9,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145125012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of the Efficacy of Low-Energy Delicate Pulsed Light and Q-Switched 1064 nm Nd:YAG Laser in the Treatment of Post-Acne Erythema: A Prospective Randomized Split-Face Study 低能量精细脉冲光与调q 1064 nm Nd:YAG激光治疗痤疮后红斑的疗效比较:一项前瞻性随机裂面研究。
IF 1.9 3区 医学
Lasers in Surgery and Medicine Pub Date : 2025-09-09 DOI: 10.1002/lsm.70064
Hongshan Liu, Luyue Zhang, Ziyun Gao, Jingchen Liang, Yuxin Ma, Youbao Li, Jing Liu, Weihui Zeng
{"title":"Comparison of the Efficacy of Low-Energy Delicate Pulsed Light and Q-Switched 1064 nm Nd:YAG Laser in the Treatment of Post-Acne Erythema: A Prospective Randomized Split-Face Study","authors":"Hongshan Liu,&nbsp;Luyue Zhang,&nbsp;Ziyun Gao,&nbsp;Jingchen Liang,&nbsp;Yuxin Ma,&nbsp;Youbao Li,&nbsp;Jing Liu,&nbsp;Weihui Zeng","doi":"10.1002/lsm.70064","DOIUrl":"10.1002/lsm.70064","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Post-acne erythema (PAE), a common consequence of acne, is characterized by capillary dilation and erythema, which significantly impact facial aesthetics and quality of life. This study aims to evaluate and compare the efficacy and safety of intense pulsed light (DPL) and 1064 nm Q-switched Nd:YAG laser in treating PAE.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This prospective, randomized, self-controlled, evaluator-blinded clinical trial compared DPL and 1064 nm Q-switched Nd:YAG laser treatments on one side of the face, with biweekly sessions for 6 weeks. Patients were assessed during the treatment period using the VISIA 6.0 system, CEA scale, GAIS, and skin physiological parameters. Photographs were taken before and after each session, and adverse reactions and pain were recorded. Data analysis was performed using SPSS software, with <i>p</i>-values &lt; 0.05 considered significant.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 26 patients were enrolled, all completing follow-up. Both treatments significantly reduced PAE lesions (<i>p</i> &lt; 0.001) compared with baseline, with the DPL group showing more significant improvement from Week 8. After six treatments, both groups showed significant reductions in erythema index and red zone area (<i>p</i> &lt; 0.001), with no significant differences between the groups (<i>p</i> &gt; 0.05). The DPL group had significantly lower CEA scores at week 8 (<i>p</i> &lt; 0.043), but no significant difference was found at Week 12. Both treatments improved wrinkles (<i>p</i> &lt; 0.001), with the Nd:YAG group showing better skin elasticity recovery (<i>p</i> = 0.044). GAIS scores indicated significant improvement in both treatments. Patient satisfaction was 92.31%, with the DPL group slightly higher. No pigmentation or depigmentation was observed, ensuring good safety.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Both DPL and low-dose Q-switched 1064 nm Nd:YAG laser effectively treat PAE. DPL yields better early results, while Q-switched Nd:YAG laser improves skin retraction more effectively. Both are safe, well-tolerated options for PAE therapy.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17961,"journal":{"name":"Lasers in Surgery and Medicine","volume":"57 9","pages":"716-725"},"PeriodicalIF":1.9,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145030170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Body Shaping and Skin Appearance Improvement in the Abdomen and Flanks by Radiofrequency Technology 利用射频技术改善腹部和腹部的体型和皮肤外观。
IF 1.9 3区 医学
Lasers in Surgery and Medicine Pub Date : 2025-09-04 DOI: 10.1002/lsm.70059
Alejandra Fernández Santos, Alejandra Iglesias Fernández, Lorena Suárez Fernández, Leticia Huergo Zapico, Susana Valero Freitag
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