Lab AnimalPub Date : 2024-11-26DOI: 10.1038/s41684-024-01484-2
Alexandra Le Bras
{"title":"Synthetic DNA confers cell-specificity","authors":"Alexandra Le Bras","doi":"10.1038/s41684-024-01484-2","DOIUrl":"10.1038/s41684-024-01484-2","url":null,"abstract":"","PeriodicalId":17936,"journal":{"name":"Lab Animal","volume":"53 12","pages":"356-356"},"PeriodicalIF":5.9,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142713009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lab AnimalPub Date : 2024-11-26DOI: 10.1038/s41684-024-01479-z
Jorge Ferreira
{"title":"Drosophila model for tau trafficking","authors":"Jorge Ferreira","doi":"10.1038/s41684-024-01479-z","DOIUrl":"10.1038/s41684-024-01479-z","url":null,"abstract":"","PeriodicalId":17936,"journal":{"name":"Lab Animal","volume":"53 12","pages":"355-355"},"PeriodicalIF":5.9,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142713015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lab AnimalPub Date : 2024-11-26DOI: 10.1038/s41684-024-01488-y
Alexandra Le Bras
{"title":"Studying microglia’s role in APOE4-related pathology","authors":"Alexandra Le Bras","doi":"10.1038/s41684-024-01488-y","DOIUrl":"10.1038/s41684-024-01488-y","url":null,"abstract":"","PeriodicalId":17936,"journal":{"name":"Lab Animal","volume":"53 12","pages":"360-360"},"PeriodicalIF":5.9,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41684-024-01488-y.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142714745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lab AnimalPub Date : 2024-11-26DOI: 10.1038/s41684-024-01481-5
Jorge Ferreira
{"title":"COVID-19 affects vitamin D metabolism in the kidney","authors":"Jorge Ferreira","doi":"10.1038/s41684-024-01481-5","DOIUrl":"10.1038/s41684-024-01481-5","url":null,"abstract":"","PeriodicalId":17936,"journal":{"name":"Lab Animal","volume":"53 12","pages":"355-355"},"PeriodicalIF":5.9,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142713082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lab AnimalPub Date : 2024-11-26DOI: 10.1038/s41684-024-01486-0
Jorge Ferreira
{"title":"Sex differences in response to stress and alcohol abuse","authors":"Jorge Ferreira","doi":"10.1038/s41684-024-01486-0","DOIUrl":"10.1038/s41684-024-01486-0","url":null,"abstract":"","PeriodicalId":17936,"journal":{"name":"Lab Animal","volume":"53 12","pages":"358-358"},"PeriodicalIF":5.9,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41684-024-01486-0.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142714737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lab AnimalPub Date : 2024-11-25DOI: 10.1038/s41684-024-01473-5
Cedric Moro, Christophe Magnan
{"title":"Revisited guidelines for metabolic tolerance tests in mice","authors":"Cedric Moro, Christophe Magnan","doi":"10.1038/s41684-024-01473-5","DOIUrl":"10.1038/s41684-024-01473-5","url":null,"abstract":"Preclinical mouse models are extensively used in biomedical research to gain insight into disease mechanisms and to test new drug treatments. Glucose and insulin tolerance tests are simple experimental tests frequently used worldwide to assess glucose metabolism in mice. Various guidelines and methodological considerations have been published to help researchers standardize procedures and optimize research outcomes. Yet, there is still important experimental heterogeneity in the way these simple procedures are performed, with no real consensus on what the best practices are to achieve high-quality research and reproducible results. Here we critically examine several published guidelines and recent technical reports on how to perform these metabolic tests in laboratory mice and discuss the influence of various confounding factors on test results. We hope this work will help scientists establish more consensual guidelines for maximizing the relevance and clinical translation of studies using mouse models in metabolic research. In this Review, the authors examine current guidelines for metabolic tolerance tests in mice and provide a set of revisited recommendations to improve the reproducibility and clinical translation of the findings.","PeriodicalId":17936,"journal":{"name":"Lab Animal","volume":"54 1","pages":"16-23"},"PeriodicalIF":5.9,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41684-024-01473-5.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142697096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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