Klinische Monatsblatter fur Augenheilkunde最新文献

{"title":"Therapeutic Excimer Laser Surgery - A Review of Current Indications.","authors":"Piotr Kanclerz, Natasza Bazylczyk, Ramin Khoramnia","doi":"10.1055/a-2950-3125","DOIUrl":"https://doi.org/10.1055/a-2950-3125","url":null,"abstract":"<p><strong>Abstract: </strong>Corneal refractive procedures are considered safe and effective for correcting mild-to-moderate refractive errors. Due to the precision and popularity of excimer lasers, they have also been employed to treat other medical conditions. The present study aimed to discuss the utility of excimer laser surgery for managing medical conditions aside from natural refractive errors based on the currently available literature. PubMed and Scopus were the main resources used to search the literature as of Aug 20, 2025. The following keywords were used in various combinations: <i>refractive surgery, laser in situ keratomileusis, laser subepithelial keratomileusis, photorefractive keratectomy, phototherapeutic keratectomy, excimer laser, indications, recurrent corneal erosion syndrome, corneal dystrophy, corneal scar, corneal scarring, keratoconus, ametropia.</i> Phototherapeutic keratectomy (PTK) allows for immediate resolution of recurrent corneal erosion syndrome. However, a fifth of patients might have long-term recurrences or require lubricating eye drops. In corneal dystrophies, PTK has been used to treat erosions and opacifications. Photorefractive keratectomy might be combined with cross-linking to enhance visual outcomes in patients with keratoconus. Other indications include corneal scarring, complications associated with corneal refractive surgery, and ametropia or corneal aberrations following ocular surgeries. With the increasing availability of lasers and growing evidence, this wide range of conditions treated by excimer lasers might continue to grow.</p>","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149111644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ocular haemorrhages under antithrombotic therapy: risk factors, management and clinical perspectives.","authors":"Christoph Sucker, Oliver Zeitz, Nicolas Feltgen","doi":"10.1055/a-2937-0560","DOIUrl":"10.1055/a-2937-0560","url":null,"abstract":"<p><strong>Abstract: </strong>BACKGROUND: Spontaneous ocular haemorrhages under antithrombotic therapy are rare but can lead to persistent visual impairment up to blindness. Despite increasing prescriptions of antithrombotic medications, systematic overviews on incidence, risk factors, and management are lacking.</p><p><strong>Abstract: </strong>PATIENTS AND METHODS: Based on a selective literature review, current clinical studies, registry data, and epidemiologic analyses on spontaneous ocular haemorrhages under oral/parenteral anticoagulation and antiplatelet therapy were evaluated. The evidence was summarized regarding incidence, risk constellations, acute bleeding management, and therapy resumption.</p><p><strong>Abstract: </strong>RESULTS: The risk of ocular haemorrhages varies significantly depending on medication, comorbidity, and combination therapy. Elderly patients with arterial hypertension, impaired renal function, and pre-existing eye diseases are particularly at risk. Dual antiplatelet therapy and combinations of anticoagulants and antiplatelet agents significantly increase the risk. Among oral anticoagulants, apixaban shows the most favourable ocular bleeding profile. Acute management strategies range from systemic reversal (e.g., idarucizumab, andexanet alfa) to ophthalmologic interventions (laser, vitrectomy). Therapy resumption should be coordinated interdisciplinarily.</p><p><strong>Abstract: </strong>CONCLUSIONS: Ocular haemorrhages under antithrombotic therapy require prompt, risk-adapted management. The choice of anticoagulant, control of modifiable risk factors, and clear decision algorithms for resumption of antithrombotic therapy are essential to prevent both vision loss and thromboembolic complications.</p>","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148760216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[OCT-based measurement of intraocular lens decentration and tilt].","authors":"Pirmin Lorenz Paul Frey, Arthur Mueller, Ramin Khoramnia, Severin Mueller, Isabella Diana Baur","doi":"10.1055/a-2956-4222","DOIUrl":"https://doi.org/10.1055/a-2956-4222","url":null,"abstract":"","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149111649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevention and Treatment of Iatrogenic Keratectasia.","authors":"Anna Pretzsch, Robert Herber, Ramin Khoramnia","doi":"10.1055/a-2943-6327","DOIUrl":"https://doi.org/10.1055/a-2943-6327","url":null,"abstract":"<p><strong>Abstract: </strong>Iatrogenic keratectasia can occur as a postoperative complication following refractive laser surgery. Biomechanical weakening and the resulting steepening of the remaining corneal tissue lead to progressive myopia and irregular astigmatism, associated with a significant loss of visual acuity. The incidence of iatrogenic keratectasia is reported in the literature to range from 0.04% to 0.6%, with the risk being higher after KLEx and LASIK than after PRK. However, due to advances in preoperative diagnostic techniques and surgical procedures, incidence estimates from older studies may be only partially applicable to current clinical practice. Risk factors include a thinner cornea prior to surgery, higher myopia, genetic predisposition or undetected keratoconus. A detailed preoperative medical history and thorough clinical diagnosis are therefore very important for the prevention of iatrogenic ectasia. Precise measurement methods are available that enable a differentiated assessment of corneal topography, tomography and biomechanics. Scores such as the Ectasia Risk Score System (ERSS) and Percentage of Tissue Alteration (PTA) are used to estimate the postoperative risk of ectasia based on this information. Conservative measures such as the fitting of glasses or contact lenses are initially available for the visual rehabilitation of iatrogenic keratectasia. Corneal cross-linking is indicated particularly in cases of progressive ectasia. This procedure does not aim to improve vision immediately, but it can halt further progression. The safety and effectiveness of the procedure have been proven in various studies. Alternatives include the implantation of plastic corneal ring segments (ICRS), donor corneas (CAIRS) or, as a last resort, keratoplasty. The latest surgical method involves the implantation of stromal lenticles obtained from KLEx procedures. Overall, this is a complex disease, which is why, in addition to accurate preoperative diagnostics, regular postoperative check-ups after refractive laser surgery are recommended in order to detect and treat ectasia at an early stage.</p>","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149111630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Oculoplastic management of basal cell carcinomas in congenital ichthyosis].","authors":"Lucas Johannes van Boemmel, Kristin Peters, Silvia Ribback, Frank Tost","doi":"10.1055/a-2947-9729","DOIUrl":"https://doi.org/10.1055/a-2947-9729","url":null,"abstract":"","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149081367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Transient Bilateral Cataract during Intensive Glucose Control in an Adolescent with Type 1 Diabetes Mellitus].","authors":"Tarek Aljarmakani, Sebastian Bemme","doi":"10.1055/a-2954-2363","DOIUrl":"10.1055/a-2954-2363","url":null,"abstract":"","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148906595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Subretinal Fluid Resolution in Dome-Shaped Maculopathy After Vitrectomy with Air Tamponade.","authors":"Peter Kiraly, Tsveta Ivanova, Assad Jalil","doi":"10.1055/a-2953-4435","DOIUrl":"10.1055/a-2953-4435","url":null,"abstract":"","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148891906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Therapeutic Success and Revision Rate after Preserflo MicroShunt Implantation: A Monocentric Analysis of 74 Cases.","authors":"Gloria Helmers, Daniel Böhringer, Philip Keye, Patrick Thelen, Thomas Reinhard, Jan Luebke","doi":"10.1055/a-2944-0690","DOIUrl":"10.1055/a-2944-0690","url":null,"abstract":"<p><strong>Abstract: </strong>BACKGROUND: Filtrating surgeries have been the gold standard in glaucoma surgery for decades, yet fibrotic processes remain a major cause of therapeutic failure. Modern glaucoma surgeries aim to offer a less invasive alternative but are often less effective in reducing intraocular pressure (IOP). The Preserflo MicroShunt combines the principles of traditional filtering surgery with minimally invasive techniques to achieve an effective IOP reduction.</p><p><strong>Abstract: </strong>PATIENTS AND METHODS: This retrospective, single-centre study analysed the clinical data of 74 patients who underwent Preserflo MicroShunt implantation in a university eye clinic between 2021 and 2022. The mean age was 71.1 ± 10.3 years. The most common glaucoma types were primary open-angle glaucoma (52.7%), pseudoexfoliation glaucoma (22.9%), normal-tension glaucoma (9.4%), and angle-closure glaucoma (4%). The median follow-up time was 326 days. Treatment success was evaluated based on IOP, revision rates, and the necessity of additional pressure-lowering interventions using descriptive statistics and Kaplan-Meier analysis.</p><p><strong>Abstract: </strong>RESULTS: After approximately 1 year (326 days), 38.0% achieved absolute success (IOP ≤ 18 mmHg and ≥20% reduction from baseline without additional medication), while 39.9% achieved relative success (IOP ≤ 18 mmHg and ≥20% reduction, including topical medication). No further IOP-lowering interventions were required in 78.7% of cases, and 63.8% of patients did not require a revision of the Preserflo implant.</p><p><strong>Abstract: </strong>CONCLUSION: This monocentric study presents current, consistent data from our clinic on the efficacy of the Preserflo MicroShunt in glaucoma patients, thereby complementing existing evidence on comparable filtering procedures. The observed success rates were slightly lower than those reported for other procedures, possibly due to the tertiary referral setting, complex pre-treatment histories, and the retrospective study design with non-standardized follow-up intervals and decreasing long-term risk populations. Longer prospective studies are needed to assess long-term efficacy and safety outcomes.</p>","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148977170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Beyond Emmetropia: Target Refraction in Unilateral Cataract Associated with Fuchs Uveitis Syndrome].","authors":"Lukas Maximilian Möhwald, Emanuel Valentin Reitemeyer, Maximilian Hammer, Alexander Lukas Rattunde, David Muallah, Ricardo Elsner, Jasmin Abu Arif, Sabine Popa, Tim Rüterhenke, Reem Alshammari, Joris De Keersmaecker, Lynn Sophie Zur Bonsen, Eckart Bertelmann, Ramin Khoramnia","doi":"10.1055/a-2950-6743","DOIUrl":"10.1055/a-2950-6743","url":null,"abstract":"","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148874391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison and Analysis of Same-Day Repeated Swept-Source Optical Coherence Tomography Biometry Scans.","authors":"Deanna H Dang, Karanpreet S Multani, Michael Cheng, David A Murphy, Kai D Ding, Jascha A Wendelstein, David L Cooke, Kamran M Riaz","doi":"10.1055/a-2948-7753","DOIUrl":"10.1055/a-2948-7753","url":null,"abstract":"<p><strong>Abstract: </strong>BACKGROUND: To evaluate the effectiveness of same-day repeated scans using a swept-source optical coherence tomography (SS-OCT) biometer (IOLMaster 700) when the initial scan resulted in a \"warning\" and/or \"failed\" variable.</p><p><strong>Abstract: </strong>METHODS: This is a retrospective observational cohort study at a tertiary care academic referral center. Among 5619 SS-OCT biometer scans reviewed between 2017 and 2021, 2293 met the inclusion criteria with 1167 same-day rescans. Each scan's variables received a \"successful,\" \"warning,\" or \"failed\" result across nine biometric parameters: axial length, anterior chamber depth, central corneal thickness, keratometry, lens thickness, posterior keratometry, total keratometry, white-to-white distance, and aqueous depth. Scans achieving \"successful\" results for all nine variables were deemed \"perfect scans.\" Warning and failed results were analyzed separately for per-parameter analyses given their differing clinical implications for IOL power calculation.</p><p><strong>Abstract: </strong>RESULTS: After excluding perfect initial scans, among 909 suspect sessions, only 361 (38.1%) rescans yielded better results, while 587 (61.9%) demonstrated an identical or worse outcome (95% CI: 59-65%, <i>p</i> < 0.001). When analyzing all nine variables across all rescans, the subsequent scan showed an identical or worse outcome in 804 (68.9%) cases (95% CI: 66-72%, <i>p</i> < 0.001). In rescans where the initial scan received a \"warning\" or \"failed\" result for any individual variable, 35.8-56.0% improved depending on the parameter. Among improved scans, mean absolute differences were minimal, suggesting limited clinical significance.</p><p><strong>Abstract: </strong>CONCLUSIONS: Repeat scans improve the quality of biometric measurements in eyes showing warning or failed results from the studied SS-OCT biometer in fewer than half of cases for most parameters.</p>","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148850945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}