Johanna Wiedemann, Christopher Dicke, Björn O Bachmann, Lebriz Altay, Claus Cursiefen
{"title":"[Cystoid macular edema (CME) and immune responses after DMEK/Triple DMEK: Real-life data from Oregis].","authors":"Johanna Wiedemann, Christopher Dicke, Björn O Bachmann, Lebriz Altay, Claus Cursiefen","doi":"10.1055/a-2650-9712","DOIUrl":"https://doi.org/10.1055/a-2650-9712","url":null,"abstract":"","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144591579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christoph Holtmann, Mathias Roth, Gesine Szurman, Ulrike Grenzebach, Norbert Schrage, Christian Brinkmann, Bettina Wabbels, Burkhard Dick, Markus Kohlhaas, Gernot Freißler, Marc Schargus, Lutz Hesse, Johann Roider, Agata Anna Wykrota, Arthur Müller, Gangolf Sauder, Frank Tost, Jürgen Walther, Andreas Scheider, Mathias M Maier, Kathi Hartmann, Eckart Bertelmann, Christoph Hintschich, Markus Ladewig, Anja Eckstein, Thomas Reinhard, Michael P Schittkowski, Alexander C Rokohl, Ludwig Maximilian Heindl, Ina Sterker, Salvatore Grisanti, Giulia Renieri, Heike Maria Elflein, Tobias Brockmann, Patrizia Krauss, Karsten Hufendiek, Volker Besgen, Katja Ruediger, Jens Heichel, Arne Viestenz, Maria Borrelli, Gerd Geerling
{"title":"[Orbital floor fractures in Germany: Interdisciplinary care without a uniform standard - results of a multicenter survey].","authors":"Christoph Holtmann, Mathias Roth, Gesine Szurman, Ulrike Grenzebach, Norbert Schrage, Christian Brinkmann, Bettina Wabbels, Burkhard Dick, Markus Kohlhaas, Gernot Freißler, Marc Schargus, Lutz Hesse, Johann Roider, Agata Anna Wykrota, Arthur Müller, Gangolf Sauder, Frank Tost, Jürgen Walther, Andreas Scheider, Mathias M Maier, Kathi Hartmann, Eckart Bertelmann, Christoph Hintschich, Markus Ladewig, Anja Eckstein, Thomas Reinhard, Michael P Schittkowski, Alexander C Rokohl, Ludwig Maximilian Heindl, Ina Sterker, Salvatore Grisanti, Giulia Renieri, Heike Maria Elflein, Tobias Brockmann, Patrizia Krauss, Karsten Hufendiek, Volker Besgen, Katja Ruediger, Jens Heichel, Arne Viestenz, Maria Borrelli, Gerd Geerling","doi":"10.1055/a-2642-2470","DOIUrl":"https://doi.org/10.1055/a-2642-2470","url":null,"abstract":"","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144484911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Julia Prinz, Kathi Hartmann, Peter Walter, Tibor Lohmann, Matthias Fuest, David Kuerten
{"title":"Tendon Elongation with Fascia Lata Grafts in Strabismus Surgery - Multiple Indications Apart from Graves' Orbitopathy.","authors":"Julia Prinz, Kathi Hartmann, Peter Walter, Tibor Lohmann, Matthias Fuest, David Kuerten","doi":"10.1055/a-2611-2250","DOIUrl":"https://doi.org/10.1055/a-2611-2250","url":null,"abstract":"<p><strong>Background: </strong>To investigate the use of fascia lata (FL) grafts for eye muscle tendon elongation in patients with complex and residual strabismus types apart from Graves' orbitopathy.</p><p><strong>Methods and materials: </strong>In this retrospective study, a heterogeneous group of 27 eyes of 21 patients with complex and residual strabismus types who underwent elongation of the eye muscle tendon with FL were included. Orthoptic and ophthalmological examinations including measurement of the head posture, the extent of deviation in primary position (PP), and monocular excursion were conducted preoperatively and after a mean postoperative time of 12.2 (6.0 - 37.0, median 7.0) months in all patients.</p><p><strong>Results: </strong>Eight patients (12 eyes) with residual exotropia, 4 patients (4 eyes) with residual esotropia, 4 patients (6 eyes) with partial abducens nerve palsy, 4 patients (4 eyes) with vertical deviation, and 1 patient (1 eye) with Duane's retraction syndrome (DRS) type I were included. A residual squint angle of 10Δ or less was achieved in 57.1% of the patients at the last follow-up. The head posture was significantly reduced at the last follow-up compared to preoperatively in patients with residual exotropia (p = 0.002), esotropia (p = 0.040), abducens nerve palsy (p = 0.005), and vertical deviation (p = 0.005). At the last follow-up, a significant reduction in the squint angle occurred in patients with residual exotropia (p = 0.001), abducens nerve palsy (p = 0.046), and vertical deviation (p = 0.033).</p><p><strong>Conclusion: </strong>FL grafts may offer safe and effective surgical options for complex and residual strabismus types. No significant reduction in the excursion into the fields of action of the affected muscles was witnessed.</p>","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144310115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Peter Wolfrum, Anna Maria Voigt, Katrin Lorenz, Bernhard M Stoffelns, Christina A Korb
{"title":"Real-world Efficacy, Safety, and the Impact of Spherical Equivalent on Intravitreal Anti-VEGF Therapy in Patients Affected by Myopic Choroidal Neovascularisation.","authors":"Peter Wolfrum, Anna Maria Voigt, Katrin Lorenz, Bernhard M Stoffelns, Christina A Korb","doi":"10.1055/a-2561-2847","DOIUrl":"https://doi.org/10.1055/a-2561-2847","url":null,"abstract":"<p><strong>Purpose: </strong>To analyse real-world clinical outcomes and influence of the spherical equivalent (SE) on anti-vascular endothelial growth factor (VEGF) therapy in patients affected by myopic choroidal neovascularisation (mCNV).</p><p><strong>Patients and methods: </strong>A retrospective investigation was conducted on treatment-naïve mCNV patients receiving anti-VEGF therapy at the Department of Ophthalmology, University Medical Center Mainz, Germany, between January 2018 and March 2024. Safety, functional and morphological changes in visual acuity (VA), central retinal thickness (CRT), and central retinal volume (CRV) were evaluated over a two-year period. Further, we analysed how baseline VA and CRT relate to it's final outcome measures. Finally, a subgroup analysis assessed the impact of SE above and below - 10 D.</p><p><strong>Results: </strong>Significant improvements in VA, CRT, and CRV were observed. VA improved from 0.5 ± 0.27 logMAR to 0.38 ± 0.31 logMAR (<i>p</i> = 0.005) at 6 months and remained stable at 2 years. CRT and CRV decreased from 344.4 ± 115.0 µm to 284.2 ± 45.2 µm (<i>p</i> < 0.001) and 0.27 ± 0.09 mm³ to 0.22 ± 0.04 mm³ (<i>p</i> < 0.001), respectively, four weeks after the initial injection, with stability maintained thereafter. Baseline VA correlated strongly with final VA, whereas CRT did not. No adverse events were reported. The subgroup analysis showed no significant outcome differences based on SE.</p><p><strong>Conclusion: </strong>Anti-VEGF therapy in mCNV patients proved to be safe and effective in our study with sustained improvement in functional and anatomical measures. Baseline VA strongly predicted final VA, whereas baseline and final CRT showed no association. No differences in treatment outcomes were observed as based on a varying SE.</p>","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144275276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dimitrios Kalogeropoulos, Samir Khandhadia, Fatima Shawkat, Andrew John Lotery
{"title":"A Rare Case of CLN3-associated Isolated Retinal Degeneration with Macular Oedema.","authors":"Dimitrios Kalogeropoulos, Samir Khandhadia, Fatima Shawkat, Andrew John Lotery","doi":"10.1055/a-2577-9808","DOIUrl":"https://doi.org/10.1055/a-2577-9808","url":null,"abstract":"","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144216295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Niklas Schön, Patrick K Peschke, Warda Darwisch, Clara Eileen Englisch, Annekatrin Rickmann
{"title":"[Foveal Red Spot Syndrome - Diagnosis on Sight?]","authors":"Niklas Schön, Patrick K Peschke, Warda Darwisch, Clara Eileen Englisch, Annekatrin Rickmann","doi":"10.1055/a-2604-4288","DOIUrl":"https://doi.org/10.1055/a-2604-4288","url":null,"abstract":"","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144216294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ansgar Beuse, Carsten Grohmann, Hauke M Schadwinkel, Christos Skevas, Martin S Spitzer
{"title":"Artificial Intelligence for the Detection of Diabetic Retinopathy.","authors":"Ansgar Beuse, Carsten Grohmann, Hauke M Schadwinkel, Christos Skevas, Martin S Spitzer","doi":"10.1055/a-2545-1192","DOIUrl":"https://doi.org/10.1055/a-2545-1192","url":null,"abstract":"<p><p>Screening and timely treatment can avoid the majority of severe vision loss and blindness from diabetic retinopathy. Artificial intelligence (AI) algorithms that detect DR from retinal photographs without human assessment might reduce the challenges of systematic screening. The German National Care Guideline recommends that individuals with diabetes receive annual or biennial eye examinations to detect treatable DR. Efficient and comprehensive screening of the growing diabetic population requires more and more resources. Artificial intelligence (AI) algorithms that detect DR from retinal photographs without human assessment might help in coping with the immense screening burden. Many of these AI algorithms have achieved good sensitivity and specificity for detecting treatable DR, as compared to human graders; however, many important challenges remain, such as acceptance, cost-effectiveness, liability issues, IT security, and reimbursement. AI-supported DR screening has so far only been used to a limited extent, even in countries with a developed digital infrastructure. These questions must be addressed before AI-based DR screening can be implemented on a large scale into clinical practice. This overview presents key concepts in development and currently approved AI applications for DR screening.</p>","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144208900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}