Solveig Severin, Filip S Filev, Burkhard von Jagow
{"title":"[Intravitreal Faricimab Injections for Coats Disease: a Case Report].","authors":"Solveig Severin, Filip S Filev, Burkhard von Jagow","doi":"10.1055/a-2556-6303","DOIUrl":"https://doi.org/10.1055/a-2556-6303","url":null,"abstract":"","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144000834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tim Berger, Berthold Seitz, Shady Suffo, Ranko Gvozdenovic, Yaser Abu Dail, Loay Daas
{"title":"Fellow Eye Comparison of Tomographic Parameters and Higher-Order Aberrations in Ultrathin Descemet Stripping Automated Endothelial Keratoplasty and Descemet Membrane Endothelial Keratoplasty.","authors":"Tim Berger, Berthold Seitz, Shady Suffo, Ranko Gvozdenovic, Yaser Abu Dail, Loay Daas","doi":"10.1055/a-2558-2583","DOIUrl":"https://doi.org/10.1055/a-2558-2583","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the functional outcomes of ultrathin Descemet stripping automated endothelial keratoplasty (UT-DSAEK) and Descemet membrane endothelial keratoplasty (DMEK) for Fuchs endothelial corneal dystrophy in fellow eyes.</p><p><strong>Methods: </strong>Retrospective study of 28 eyes (14 patients) undergoing UT-DSAEK in one eye and DMEK in the fellow eye with a follow-up of at least one year. Main outcomes were best-corrected visual acuity (BCVA), central corneal thickness (CCT), endothelial cell density (ECD), and anterior and posterior tomographic parameters, including corneal higher-order aberrations (HOAs).</p><p><strong>Results: </strong>The UT-DSAEK and DMEK groups showed no differences in donor characteristics or preoperative corneal tomographic parameters. BCVA improved in both groups, but visual recovery was faster in the DMEK group. CCT and ECD decreased in the UT-DSAEK and DMEK groups, but without differences between the groups. Posterior mean keratometry and posterior Q-value increased in the UT-DSAEK and DMEK groups with higher values of both parameters in the UT-DSAEK group. As regards corneal aberrations, higher root mean-square values for HOAs of the posterior cornea and higher values of posterior Trefoil were evident in the UT-DSAEK group than in the DMEK group.</p><p><strong>Conclusion: </strong>Visual quality after endothelial keratoplasty might depend not on visual acuity alone, but also on corneal aberrations and asphericity of the anterior and posterior corneal surface. The results support the benefits of DMEK over UT-DSAEK, suggesting the need for long-term studies with a larger number of patients.</p>","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144031318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Influence of Time Spent Viewing the Video Display Terminal, Sleep, Anxiety and Depression on the Thickness of the Lipid Layer of the Tear Film.","authors":"Xiufen Liu, Dandan Zhou, Yu Ren, Qian Li, Dan Li, Siying Teng, Fei Shao, Tianlong He, Huizhong Zhou, Nuerailimu Yimingtuohuti, Jia Li, Cheng-Wei Lu","doi":"10.1055/a-2522-3838","DOIUrl":"10.1055/a-2522-3838","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the influence of time spent viewing a video display terminal (VDTt), sleep, anxiety, and depression on the thickness of the lipid layer of the tear film (LLT).</p><p><strong>Methods: </strong>This is a cross-sectional study. A total of 102 patients were enrolled. Their ocular surface disease index (OSDI), Standard Patient Evaluation of Eye Dryness (SPEED) questionnaire, Pittsburgh Sleep Quality Index (PSQI), Hospital Anxiety and Depression Scale anxiety subscale (HADS-A), and depression subscale (HADS-D) were recorded. The LLT, meibomian gland secretion quality, tear film break-up time (TBUT), conjunctival hyperemia grade, corneal staining score, and VDTt were also evaluated. Spearman analysis was used to analyze the correlation. The patients were divided into the thinner LLT group (LLT < 75 nm) and the thicker LLT group (LLT ≥ 75 nm). The Mann-Whitney U test was used to analyze the characteristics and to compare the two groups. The receiver operating characteristic (ROC) curve was used to predict the relationship between VDTt and LLT.</p><p><strong>Results: </strong>Spearman correlation analysis showed a significant positive correlation between TBUT and average LLT, and significant negative correlations between mean LLT and OSDI, SPEED, meibomian gland secretion quality, conjunctival hyperemia, corneal staining, VDTt, PSQI, and HADS-A. In comparison to the thick LLT group, the thin LLT group had a worse OSDI score, shorter TBUT, longer VDTt, worse PSQI and HADS-A scores. The ROC curve indicated that the optimal cutoff value for using VDT to predict LLT less than 75 nm is 8.25 hours.</p><p><strong>Conclusion: </strong>The thinner LLT had worse questionnaire scores and signs related to dry eye, which indicates that a thinner LLT is more prone to causing dry eye. Using VDTt for more than 8.25 hours is more likely to induce thinning of the LLT, thereby increasing the risk of dry eye. Patients with a sleep disorder and anxiety are more susceptible to thinning of the LLT, suggesting that they are prone to developing dry eye syndrome.</p>","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143023951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amr Saad, Ferhat Turgut, Matthias Becker, Delia DeBuc, Gabor Mark Somfai
{"title":"Stakeholder Attitudes on AI Integration in Ophthalmology.","authors":"Amr Saad, Ferhat Turgut, Matthias Becker, Delia DeBuc, Gabor Mark Somfai","doi":"10.1055/a-2543-4330","DOIUrl":"https://doi.org/10.1055/a-2543-4330","url":null,"abstract":"<p><p>Artificial intelligence (AI) is gaining widespread traction in ophthalmology, with multiple screening and diagnostic tools already being approved by U. S. and EU authorities. However, the adoption of these tools among medical professionals and their acceptance among patients is still questionable. This narrative review analyses the current literature on stakeholder perspectives on the integration of AI in ophthalmology, with a focus on comparing views across different global healthcare contexts. A PubMed search was conducted for original research articles published between January 1, 2015 and August 31, 2024. The analysis revealed different levels of acceptance for different AI applications among different stakeholder groups. Ophthalmologists and optometrists generally showed positive attitudes toward AI as an adjunct tool, while patients expressed mixed views, appreciating potential benefits while expressing concerns about a lack of transparency in the integration of AI into healthcare. This review reveals a complex landscape of stakeholder perspectives on AI in ophthalmology, highlighting the need for tailored approaches to AI implementation that address specific concerns and consider different healthcare contexts. The findings underscore the importance of collaborative efforts to develop context-specific, effective AI solutions in ophthalmology.</p>","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":"242 4","pages":"515-520"},"PeriodicalIF":0.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12020675/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144024671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tahm Spitznagel, Katrin Fasler, Jay Zoellin, Jeanne Martine Gunzinger, Chiara Sommer, Stephan Kinzl, Daniel Rudolf Muth, Ferhat Turgut, Amr Saad, Matthias Becker, Gabor Mark Somfai, Sandrine Zweifel
{"title":"Evaluating Photodynamic Therapy vs. Subthreshold Micropulse Laser for Central Serous Chorioretinopathy: A Retrospective Study.","authors":"Tahm Spitznagel, Katrin Fasler, Jay Zoellin, Jeanne Martine Gunzinger, Chiara Sommer, Stephan Kinzl, Daniel Rudolf Muth, Ferhat Turgut, Amr Saad, Matthias Becker, Gabor Mark Somfai, Sandrine Zweifel","doi":"10.1055/a-2542-4969","DOIUrl":"https://doi.org/10.1055/a-2542-4969","url":null,"abstract":"<p><strong>Background: </strong>Our study aims to compare the efficacy of half-dose photodynamic therapy with verteporfin (PDT) and subthreshold micropulse laser (SML) in patients with central serous chorioretinopathy (CSCR) with regards to subretinal fluid (SRF) resorption, visual acuity (VA), and central subfield thickness (CST).</p><p><strong>Patients and methods: </strong>We conducted a retrospective multicentre clinical study at the Departments of Ophthalmology at the University Hospital Zurich and Stadtspital Zürich, Switzerland. The study included patients with acute and chronic CSCR who underwent PDT, SML, or both sequentially between June 1, 2020 and December 31, 2023. The primary outcome was the reduction in SRF at three and six months post-treatment. The secondary outcomes included change in CST VA at the same intervals.</p><p><strong>Results: </strong>A total of eighty-one eyes were analysed (33 PDT, 35 SML, thirteen combined). SRF reduction was statistically significant at both three and six months in the PDT (p < 0.001) and SML groups (p < 0.001). The combined treatment group showed a significant reduction in SRF only at six months (p = 0.001). At three months, PDT resulted in a significantly greater SRF reduction than the combined group.</p><p><strong>Conclusions: </strong>Both PDT and SML demonstrated improvements in SRF, CST and VA, with SML presenting as a comparable alternative, particularly in cases where access to verteporfin is limited.</p>","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":"242 4","pages":"405-412"},"PeriodicalIF":0.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12020661/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144028791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Long-term Follow-up of an Atypical Macular Hole Treated with 25 G Pars Plana Vitrectomy (ppV), ILM Peeling and 16% C2F6 Gas Tamponade.","authors":"Andreas Weinberger, Marko Vlasic, Tamer Tandogan","doi":"10.1055/a-2520-9568","DOIUrl":"https://doi.org/10.1055/a-2520-9568","url":null,"abstract":"","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":"242 4","pages":"445-447"},"PeriodicalIF":0.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144032467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}