Klinische Monatsblatter fur Augenheilkunde最新文献

Spontaneous Closure of Full-Thickness Macular Hole in a Patient with Retinal Arteriovenous Malformation: Sixteen-Year Follow-up. 视网膜动静脉畸形患者全层黄斑孔自动闭合：16年随访。

IF 0.8 4区医学

Klinische Monatsblatter fur Augenheilkunde Pub Date : 2025-06-16 DOI: 10.1055/a-2550-0839

Zeynep Serikoglu Akbas, Faik Gelisken, Benedikt Rössler

引用次数: 0

Tendon Elongation with Fascia Lata Grafts in Strabismus Surgery - Multiple Indications Apart from Graves' Orbitopathy. 斜视手术中阔筋膜肌腱伸长术-除Graves眼病外的多种适应症。

IF 0.8 4区医学

Klinische Monatsblatter fur Augenheilkunde Pub Date : 2025-06-16 DOI: 10.1055/a-2611-2250

Julia Prinz, Kathi Hartmann, Peter Walter, Tibor Lohmann, Matthias Fuest, David Kuerten

{"title":"Tendon Elongation with Fascia Lata Grafts in Strabismus Surgery - Multiple Indications Apart from Graves' Orbitopathy.","authors":"Julia Prinz, Kathi Hartmann, Peter Walter, Tibor Lohmann, Matthias Fuest, David Kuerten","doi":"10.1055/a-2611-2250","DOIUrl":"https://doi.org/10.1055/a-2611-2250","url":null,"abstract":"Background: To investigate the use of fascia lata (FL) grafts for eye muscle tendon elongation in patients with complex and residual strabismus types apart from Graves' orbitopathy.Methods and materials: In this retrospective study, a heterogeneous group of 27 eyes of 21 patients with complex and residual strabismus types who underwent elongation of the eye muscle tendon with FL were included. Orthoptic and ophthalmological examinations including measurement of the head posture, the extent of deviation in primary position (PP), and monocular excursion were conducted preoperatively and after a mean postoperative time of 12.2 (6.0 - 37.0, median 7.0) months in all patients.Results: Eight patients (12 eyes) with residual exotropia, 4 patients (4 eyes) with residual esotropia, 4 patients (6 eyes) with partial abducens nerve palsy, 4 patients (4 eyes) with vertical deviation, and 1 patient (1 eye) with Duane's retraction syndrome (DRS) type I were included. A residual squint angle of 10Δ or less was achieved in 57.1% of the patients at the last follow-up. The head posture was significantly reduced at the last follow-up compared to preoperatively in patients with residual exotropia (p = 0.002), esotropia (p = 0.040), abducens nerve palsy (p = 0.005), and vertical deviation (p = 0.005). At the last follow-up, a significant reduction in the squint angle occurred in patients with residual exotropia (p = 0.001), abducens nerve palsy (p = 0.046), and vertical deviation (p = 0.033).Conclusion: FL grafts may offer safe and effective surgical options for complex and residual strabismus types. No significant reduction in the excursion into the fields of action of the affected muscles was witnessed.","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144310115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recurrent Exposure of the PRESERFLO MicroShunt Implant. Preserflo Microshunt 植入物反复暴露。

IF 0.8 4区医学

Klinische Monatsblatter fur Augenheilkunde Pub Date : 2025-06-13 DOI: 10.1055/a-2250-9841

Lara Borrego Sanz, Carmen Dora Méndez Hernández, Fernado Ly Yang, Verónica Gómez Calleja, Federico Sáenz-Francés San Baldomero

引用次数: 0

Real-world Efficacy, Safety, and the Impact of Spherical Equivalent on Intravitreal Anti-VEGF Therapy in Patients Affected by Myopic Choroidal Neovascularisation. 在近视脉络膜新生血管患者中，球形等效物对玻璃体内抗vegf治疗的实际疗效、安全性和影响。

IF 0.8 4区医学

Klinische Monatsblatter fur Augenheilkunde Pub Date : 2025-06-11 DOI: 10.1055/a-2561-2847

Peter Wolfrum, Anna Maria Voigt, Katrin Lorenz, Bernhard M Stoffelns, Christina A Korb

{"title":"Real-world Efficacy, Safety, and the Impact of Spherical Equivalent on Intravitreal Anti-VEGF Therapy in Patients Affected by Myopic Choroidal Neovascularisation.","authors":"Peter Wolfrum, Anna Maria Voigt, Katrin Lorenz, Bernhard M Stoffelns, Christina A Korb","doi":"10.1055/a-2561-2847","DOIUrl":"https://doi.org/10.1055/a-2561-2847","url":null,"abstract":"Purpose: To analyse real-world clinical outcomes and influence of the spherical equivalent (SE) on anti-vascular endothelial growth factor (VEGF) therapy in patients affected by myopic choroidal neovascularisation (mCNV).Patients and methods: A retrospective investigation was conducted on treatment-naïve mCNV patients receiving anti-VEGF therapy at the Department of Ophthalmology, University Medical Center Mainz, Germany, between January 2018 and March 2024. Safety, functional and morphological changes in visual acuity (VA), central retinal thickness (CRT), and central retinal volume (CRV) were evaluated over a two-year period. Further, we analysed how baseline VA and CRT relate to it's final outcome measures. Finally, a subgroup analysis assessed the impact of SE above and below - 10 D.Results: Significant improvements in VA, CRT, and CRV were observed. VA improved from 0.5 ± 0.27 logMAR to 0.38 ± 0.31 logMAR (p = 0.005) at 6 months and remained stable at 2 years. CRT and CRV decreased from 344.4 ± 115.0 µm to 284.2 ± 45.2 µm (p < 0.001) and 0.27 ± 0.09 mm³ to 0.22 ± 0.04 mm³ (p < 0.001), respectively, four weeks after the initial injection, with stability maintained thereafter. Baseline VA correlated strongly with final VA, whereas CRT did not. No adverse events were reported. The subgroup analysis showed no significant outcome differences based on SE.Conclusion: Anti-VEGF therapy in mCNV patients proved to be safe and effective in our study with sustained improvement in functional and anatomical measures. Baseline VA strongly predicted final VA, whereas baseline and final CRT showed no association. No differences in treatment outcomes were observed as based on a varying SE.","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144275276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Phlyctenular Conjunctivitis and Enterohaemorrhagic Escherichia coli Infection]. [静脉性结膜炎和肠出血性大肠杆菌感染]。

IF 0.8 4区医学

Klinische Monatsblatter fur Augenheilkunde Pub Date : 2025-06-11 DOI: 10.1055/a-2611-2362

Silvia Reichart, Matus Rehak, Wolfgang J Behrens-Baumann

引用次数: 0

A Rare Case of CLN3-associated Isolated Retinal Degeneration with Macular Oedema. 罕见的cln3相关性孤立性视网膜变性伴黄斑水肿1例。

IF 0.8 4区医学

Klinische Monatsblatter fur Augenheilkunde Pub Date : 2025-06-03 DOI: 10.1055/a-2577-9808

Dimitrios Kalogeropoulos, Samir Khandhadia, Fatima Shawkat, Andrew John Lotery

引用次数: 0

[Foveal Red Spot Syndrome - Diagnosis on Sight?] 中央凹红斑综合征-视觉诊断？］

IF 0.8 4区医学

Klinische Monatsblatter fur Augenheilkunde Pub Date : 2025-06-03 DOI: 10.1055/a-2604-4288

Niklas Schön, Patrick K Peschke, Warda Darwisch, Clara Eileen Englisch, Annekatrin Rickmann

引用次数: 0

Artificial Intelligence for the Detection of Diabetic Retinopathy. 糖尿病视网膜病变的人工智能检测。

IF 0.8 4区医学

Klinische Monatsblatter fur Augenheilkunde Pub Date : 2025-06-02 DOI: 10.1055/a-2545-1192

Ansgar Beuse, Carsten Grohmann, Hauke M Schadwinkel, Christos Skevas, Martin S Spitzer

{"title":"Artificial Intelligence for the Detection of Diabetic Retinopathy.","authors":"Ansgar Beuse, Carsten Grohmann, Hauke M Schadwinkel, Christos Skevas, Martin S Spitzer","doi":"10.1055/a-2545-1192","DOIUrl":"https://doi.org/10.1055/a-2545-1192","url":null,"abstract":"Screening and timely treatment can avoid the majority of severe vision loss and blindness from diabetic retinopathy. Artificial intelligence (AI) algorithms that detect DR from retinal photographs without human assessment might reduce the challenges of systematic screening. The German National Care Guideline recommends that individuals with diabetes receive annual or biennial eye examinations to detect treatable DR. Efficient and comprehensive screening of the growing diabetic population requires more and more resources. Artificial intelligence (AI) algorithms that detect DR from retinal photographs without human assessment might help in coping with the immense screening burden. Many of these AI algorithms have achieved good sensitivity and specificity for detecting treatable DR, as compared to human graders; however, many important challenges remain, such as acceptance, cost-effectiveness, liability issues, IT security, and reimbursement. AI-supported DR screening has so far only been used to a limited extent, even in countries with a developed digital infrastructure. These questions must be addressed before AI-based DR screening can be implemented on a large scale into clinical practice. This overview presents key concepts in development and currently approved AI applications for DR screening.","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144208900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prospective International Registry for Treatment Exit Options in Uveitis (TOFU) - the First Five Years. Uveitis （TOFU）治疗退出选择国际登记前景-头五年。

IF 0.8 4区医学

Klinische Monatsblatter fur Augenheilkunde Pub Date : 2025-06-02 DOI: 10.1055/a-2529-0057

Carsten Heinz, David J Fink, Jennifer Dell, Moritz Berger, Matthias Schmid, Robert P Finger

{"title":"Prospective International Registry for Treatment Exit Options in Uveitis (TOFU) - the First Five Years.","authors":"Carsten Heinz, David J Fink, Jennifer Dell, Moritz Berger, Matthias Schmid, Robert P Finger","doi":"10.1055/a-2529-0057","DOIUrl":"10.1055/a-2529-0057","url":null,"abstract":"Uveitis diseases are generally rare and therefore often pose a significant challenge in treatment. In developed countries, non-infectious uveitis is one of the most common causes of severe functional impairment and even blindness. The current guidelines provide information on when and how to initiate treatment, but do not include recommendations on when and how to reduce or discontinue treatment. The Treatment Exit Options for Uveitis Register (TOFU) was initiated over five years ago, with the aim of improving the evidence for therapy reduction and termination. Over the past five years, the register has been established nationally with funding from the German Federal Ministry of Education and Research (BMBF), the Eye Foundation and industry partners and has since been expanded in individual European countries. The registry is under the auspices of the Uveitis Section of the German Ophthalmological Society (DOG). The analysis of baseline data from around 1000 patients shows that, in the prospectively documented patient population, intermediate uveitis is most common, followed by posterior uveitis, panuveitis and retinal vasculitis. The disease was bilateral in 75.9% of cases. The mean visual acuity was 0.22 ± 0.36 logMAR. Patients with panuveitis had the worst visual acuity, with 0.27 ± 0.39 logMAR. Severe visual impairment (> 1.0 logMAR) was observed in only 1% of patients at baseline. The continuation and European expansion will ensure the continuous generation of high-quality data in the coming years and thus help to develop recommendations on the end of therapy.","PeriodicalId":17904,"journal":{"name":"Klinische Monatsblatter fur Augenheilkunde","volume":" ","pages":""},"PeriodicalIF":0.8,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143066454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[21-Year-old Patient with Paracentral Scotoma after Drug Abuse]. [21岁药物滥用后并发中央旁暗斑患者]。

IF 0.8 4区医学

Klinische Monatsblatter fur Augenheilkunde Pub Date : 2025-06-01 Epub Date: 2025-03-31 DOI: 10.1055/a-2570-2993

David Dietrich Beckers, Lena Beckers, Ulrich Schaudig, Birthe Stemplewitz

引用次数: 0