Journal Pharmasci (Journal of Pharmacy and Science)最新文献_第5页

Conjact Glucomannan Flour Extraction From Porang Tube (Amorphophallus muelleri Blume) with Differents Simplicia- Solvent Ratio (Subject were obtained from the Klagon Village of Saradan District) 不同溶剂比联合提取紫穗槐(Amorphophallus muelleri Blume)中葡甘露聚糖(葡甘露聚糖)的研究(实验对象来自萨拉丹区Klagon村)

Journal Pharmasci (Journal of Pharmacy and Science) Pub Date : 2021-07-28 DOI: 10.53342/pharmasci.v6i2.215

G. G. Kusumo

引用次数: 0

Effectiveness Test of Juwet Leaf Extract and Juwet Cortex Against Desreasing Blood Glucose Levels of Hiperglemic Mice 黄芪叶提取物和黄芪皮对高血糖小鼠血糖水平的降低作用试验

Journal Pharmasci (Journal of Pharmacy and Science) Pub Date : 2021-07-26 DOI: 10.53342/pharmasci.v6i2.213

P. S. Ajiningrum, S. Amilah, Wela Anies Kurela

{"title":"Effectiveness Test of Juwet Leaf Extract and Juwet Cortex Against Desreasing Blood Glucose Levels of Hiperglemic Mice","authors":"P. S. Ajiningrum, S. Amilah, Wela Anies Kurela","doi":"10.53342/pharmasci.v6i2.213","DOIUrl":"https://doi.org/10.53342/pharmasci.v6i2.213","url":null,"abstract":"Diabetes melitus drugs are currently quite expensive, so they require a cheaper and more effective substitute for drugs to control glucose levels in people with diabetes melitus. Exploring local potentials using medicinal plants can be an alternative to chemical drugs. One of the medicinal plants that is thought to be used for people with diabetes mellitus is juwet. Juwet leaves are suspected to have hypoglycemic activity, because they contain flavonoid and saponin compounds. Juwet bark also contains chemical compounds, namely flavonoids, saponins, and tannins. This study aims to determine the decrease in blood glucose levels in dextrose-induced mice by giving juwet leaf extract and juwet bark extract (Syzygium cumini L.). The test animals used were 36 male mice (Mus musculus) aged 2-3 months with a weight of 20-30 grams. This type of research was carried out experimentally and the design of this study used was Completely Randomized Design (CRD), which was divided into 12 treatments and 3 replications. The 12 treatments are juwet leaf extract and juwet bark with the same dose, namely the dose of 0 mg/kg BB, 150 mg/kg BB, 200 mg/kg BB, 250 mg/kg. Data from the research were analyzed statistically using One Way ANOVA and continued with the LSD test. The results showed that administration of juwet leaf extract and juwet bark extract at various doses had a significant effect on decreasing blood glucose levels of mice. The most effective dose to reduce blood glucose levels is juwet bark extract with a dose of 250 mg/kg BB.","PeriodicalId":17631,"journal":{"name":"Journal Pharmasci (Journal of Pharmacy and Science)","volume":"88 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81398361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of Probiotic Isolate Growth in Natural Culture with Various Carbon Sources 不同碳源自然培养中分离益生菌生长的比较

Journal Pharmasci (Journal of Pharmacy and Science) Pub Date : 2021-07-24 DOI: 10.53342/pharmasci.v6i2.218

Sitti Nur Ilmiah, Z. Dwyana, A. Abdullah

{"title":"Comparison of Probiotic Isolate Growth in Natural Culture with Various Carbon Sources","authors":"Sitti Nur Ilmiah, Z. Dwyana, A. Abdullah","doi":"10.53342/pharmasci.v6i2.218","DOIUrl":"https://doi.org/10.53342/pharmasci.v6i2.218","url":null,"abstract":"Probiotik merupakan mikroba hidup yang memberikan pengaruh menguntungkan pada inang karena dapat menyeimbangkan mikroba yang ada dalam saluran pencernaan menjadi meningkat. Pemanfaatan tersebut dapat memberikan pengaruh positif dan kesehatan bagi inang sehingga sangat baik untuk diaplikasikan. Pemanfaatan bahan alami dapat menekan biaya media tumbuh sehingga perlu penggantian media sintetik dengan media alami karena memiliki harga yang relatif lebih murah tetapi mengandung nutrien penting bagi pertumbuhan mikroba. Tujuan penelitian ini adalah untuk mengetahui pertumbuhan isolat probiotik berdasarkan lama waktu kutur dalam media alami yang mengandung sumber karbon berbeda. Pertumbuhan isolat probiotik dalam berbagai sumber karbon dilakukan melalui metode Standard Plate Count (SPC). Melalui metode SPC didapatkan jumlah koloni isolat G dari masing-masing media berupa kanji, sagu, dan dedak yaitu 2,3 x 108 Cfu/mL, 6,4 x 106 Cfu/mL, dan 4,3 x 106 Cfu/mL selama 48 jam; 2,6 x 108 Cfu/mL, 1,6 x 108 Cfu/mL, dan 1,0 x 108 Cfu/mL selama 96 jam; 4,6 x 108 Cfu/mL, 1,8 x 108 Cfu/mL, dan 1,2 x 108 Cfu/mL selama 144 jam. Hasil yang didapatkan menunjukkan bahwa isolat G mampu ditumbuhkan dalam media alami berupa kanji, sagu dan dedak.","PeriodicalId":17631,"journal":{"name":"Journal Pharmasci (Journal of Pharmacy and Science)","volume":"22 21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83714112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Detection of Heavy Metal Pb in Cosmetics at Traditional Market of Banjarmasin Banjarmasin传统市场化妆品中重金属Pb的检测

Journal Pharmasci (Journal of Pharmacy and Science) Pub Date : 2021-07-22 DOI: 10.53342/pharmasci.v6i2.220

Rahmadani, T. Alawiyah, R. Herowati

{"title":"Detection of Heavy Metal Pb in Cosmetics at Traditional Market of Banjarmasin","authors":"Rahmadani, T. Alawiyah, R. Herowati","doi":"10.53342/pharmasci.v6i2.220","DOIUrl":"https://doi.org/10.53342/pharmasci.v6i2.220","url":null,"abstract":"Background: Impurities produced from the basic ingredients of making cosmetics, one of which is lead (Pb). Lead is a substance that is harmful and toxic to the human body. Lead can affect the hematopoetic system, nervous system, reproductive system, endocrine system and is carcinogenic. Objective: To determine the presence of lead (Pb) heavy metal contamination in mascara products circulating in the Banjarmasin traditional market. Methods: This study used a descriptive observational method. Testing qualitatively using KI, NaOH, and HCl reagents. Results: The test results obtained from the sample after being reacted with the three reagents showed a positive presence of lead (Pb) heavy metal. With KI solution shows a yellow-black precipitate, with NaOH solution shows a white precipitate and with HCl solution shows a white precipitate. Conclusion: Qualitative tests on mascara cosmetic products taken at different points of sale in the Banjarmasin traditional market using color reagents in KI solution, NaOH solution, and HCl solution, it can be concluded that the qualitative test results show a positive presence of heavy metal lead (Pb). on mascara products.","PeriodicalId":17631,"journal":{"name":"Journal Pharmasci (Journal of Pharmacy and Science)","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81957867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of Antihyperlipidemic Activity Temu Mangga’s Rhizomes and Ketepeng Cina’s Leaves Infusion 铁木芒草根茎与克特蓬叶冲剂降血脂活性的比较

Journal Pharmasci (Journal of Pharmacy and Science) Pub Date : 2021-07-18 DOI: 10.53342/pharmasci.v6i2.223

D. Nugraha, N. Magfirah, Novia Henjani

{"title":"Comparison of Antihyperlipidemic Activity Temu Mangga’s Rhizomes and Ketepeng Cina’s Leaves Infusion","authors":"D. Nugraha, N. Magfirah, Novia Henjani","doi":"10.53342/pharmasci.v6i2.223","DOIUrl":"https://doi.org/10.53342/pharmasci.v6i2.223","url":null,"abstract":"Statins are first line therapy of antihyperlipidemia. It reduced LDL levels more than 50%. However, a serious side effects such as rhabdomyolisis which can lead to kidney failure. On other side, people often consumed boiled water of Temu Mangga’s Rhizome and/or Ketepeng Cina’s Leeaves as antihyperlipidemic. Both of them has a potential as adjuvant therapy. Purpose: To compare antihyperlipidemic activity of Temu Mangga’s Rhizome and Ketepeng Cina’s Leaves as alternative treatment. Method : Test animals were induced with High Fat Diet Food (HFDF) for the first 15 days, and with Temu Mangga’s Rhizome and Ketepeng Cina’s Leaves for the next 15 days. Study group: Simvastatin (positive control), Na CMC 0.5% (negative control), 450 mg/Kg BW; 900 mg/Kg BW; 1.800 mg/Kg BW of Temu Mangga’s Rhizome and 225 mg/Kg BW; 450 mg/Kg BW; and 900 mg/Kg BW Ketepeng Cina’s Leaves. Results: Temu Mangga 360 mg/200 gram BW was not significantly different from positive control in reducing total cholesterol, triglycerides, LDL and increasing HDL. Ketepeng Cina’s Leaves 180 mg/200 gram BW had the best effect, but it was not comparable to the positive control. Conclusion: 1.800 mg/Kg BW Temu Mangga’s Rhizome showed better antiyperlipidemic activity than 900 mg/Kg BW Ketepeng Cina’s Leaves.","PeriodicalId":17631,"journal":{"name":"Journal Pharmasci (Journal of Pharmacy and Science)","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85477185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Relations of Antiretroviral Combinations to CD4 Levels of HIV TB Patiens in RSUD H.Abdul Manap Jambi 抗逆转录病毒联合治疗与RSUD中HIV - TB患者CD4水平的关系

Journal Pharmasci (Journal of Pharmacy and Science) Pub Date : 2021-07-17 DOI: 10.53342/pharmasci.v6i2.198

Jelly Permatasari, Indri Meirista, Hamira Bafadhal

{"title":"Relations of Antiretroviral Combinations to CD4 Levels of HIV TB Patiens in RSUD H.Abdul Manap Jambi","authors":"Jelly Permatasari, Indri Meirista, Hamira Bafadhal","doi":"10.53342/pharmasci.v6i2.198","DOIUrl":"https://doi.org/10.53342/pharmasci.v6i2.198","url":null,"abstract":"The cases of Human Immunodeficiency Virus (HIV) infection are increasing every year. This case is a disease that is very rapidly transmitted throughout the world. HIV increases the risk of developing tuberculosis (TB) and conversely TB infection increases HIV progression. In 2017, it is estimated that 10 million people have HIV TB. Combination of antiretrovirals is the basis for the management of antiretroviral therapy for HIV / AIDS patients, because it can reduce resistance, suppress HIV replication effectively so that transmission, opportunistic infections and other complications. The purpose of this study was to determine the relationship between antiretroviral combinations and CD4 levels in outpatient HIV TB patients at RSUD H. Abdul Manap Jambi. This study is a retrospective cohort study using medical records of outpatient HIV TB patients at RSUD H. Abdul Manap Jambi based on inclusion and exclusion criteria. Based on research conducted on outpatient HIV TB patients at Abdul Manap Hospital, Jambi, it was found that there was no relationship between antiretroviral combinations and CD4 levels in HIV TB patients, marked by Asimp.Sig 0.778> 0.05.","PeriodicalId":17631,"journal":{"name":"Journal Pharmasci (Journal of Pharmacy and Science)","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78404564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Physical Evaluation of Anti Acne Mask With Ethanol Extract of Purple Sweet Potato Leaf (Ipomoea batatas (L.) Antin-3 Varieties 紫甘薯叶乙醇提取物抗痘面膜的物理评价Antin-3品种

Journal Pharmasci (Journal of Pharmacy and Science) Pub Date : 2021-07-16 DOI: 10.53342/pharmasci.v6i2.219

D. Dipahayu, K. Lestari

{"title":"Physical Evaluation of Anti Acne Mask With Ethanol Extract of Purple Sweet Potato Leaf (Ipomoea batatas (L.) Antin-3 Varieties","authors":"D. Dipahayu, K. Lestari","doi":"10.53342/pharmasci.v6i2.219","DOIUrl":"https://doi.org/10.53342/pharmasci.v6i2.219","url":null,"abstract":"Ethanol extract of purple sweet potato (Ipomoea batatas (L.)) leaves of Antin-3 variety contains flavonoids and polyphenols which can be used as a source of acne anti-bacterial because it can inhibit the growth of Staphylococcus aureus. This study aims to obtain data on physical characteristics, acceptability and stability of anti-acne mask formulation of 70% ethanol extract of Antin-3 leaves. The research method used were characteristic, acceptability and stability test. There were 4 types of samples tested, namely base, Antin-3 extract 5%: 10% and 20% (B: F1: F2: F3). The organoleptic results showed that the higher concentration of extract, the darker color of mask and the stronger of extract smell and the softer of consistency. The pH values (B: F1:F2: F3) were respectively 6.46; 5.78; 5.75; 5.46. The value of adhesion (B: F1: F2: F3) were respectively 1.1; 1.46; 2.17 and 4.53 seconds. The value of spreading capacity (B: F1: F2: F3) were respectively 3.89; 4.15; 4.36 and 3.45 cm. The results of the acceptability test showed that F2 was the easiest formula to spread, clean and softest sensation on the skin. The results of the mechanical and cycling test showed that the four samples had not undergo phase separation. Anti-acne mask with 70% ethanol extract of Antin-3 leaves by 10% met the physical characteristics, acceptability and stability.","PeriodicalId":17631,"journal":{"name":"Journal Pharmasci (Journal of Pharmacy and Science)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86918443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Analysis Of The Effect Of Age On Medication Adherence With Oral Antidiabetes And Oral Antihypertension Drugs Using Pill Count Method 用药片计数法分析年龄对口服降糖药和口服降压药依从性的影响

Journal Pharmasci (Journal of Pharmacy and Science) Pub Date : 2021-07-15 DOI: 10.53342/pharmasci.v6i2.216

N. M. Ulfa, Rizky Darmawan

{"title":"Analysis Of The Effect Of Age On Medication Adherence With Oral Antidiabetes And Oral Antihypertension Drugs Using Pill Count Method","authors":"N. M. Ulfa, Rizky Darmawan","doi":"10.53342/pharmasci.v6i2.216","DOIUrl":"https://doi.org/10.53342/pharmasci.v6i2.216","url":null,"abstract":"Compliance with taking medication is a problematic patients who get polypharmacy prescribing, this is because of the many drugs that must be consumed. As a result of the consumption of many drugs that cause sufferers of degenerative diseases are not compliant to take medication and health awareness decreases. This is not only experienced in elderly and geriatric patients but in adulthood also experience non-compliance with taking medication due to the many activities, lazy to take medication and also forget. This study was conducted to analyze the effect of age on adherence to taking oral antidiabetic drugs and oral antihypertensive drugs using the pill count method at the Regional Hospital of South Surabaya. The Pill Count method was chosen in this study with the aim of analyzing patient compliance in taking medication by calculating the remaining drug based on the rules of use and dosage when the patient returns to control. In addition, this study also aims to determine the effect of age on patient compliance in taking oral antidiabetic drugs and oral antihypertensive drugs. This research is descriptive observational with prospective data collection. Data analysis used descriptive and continued with statistical analysis using Chi-Square. The results of this study that adherence to take medication for elderly patients who received oral antidiabetic drug therapy obtained as much as 96.7% and 90% in adult patients. Compliance to oral antihypertension drugs in adult patients are 90% and 83.3% in elderly patients. Age does not effect compliance patients with Chi-Square analysis with p value = 0,301 and 0,448 > 0.05.","PeriodicalId":17631,"journal":{"name":"Journal Pharmasci (Journal of Pharmacy and Science)","volume":"43 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81643245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Potensi Antimikroba Ekstrak Ethanol Ganoderma lucidum Menggunakan Metode Bioautografi terhadap Bakteri Escherichia coli dan Bacillus subtillis 乙醇甘菊提取物的潜在抗菌素提取物采用的是

Journal Pharmasci (Journal of Pharmacy and Science) Pub Date : 2021-01-23 DOI: 10.53342/PHARMASCI.V6I1.212

Tri Puji Lestari Sudarwati, M. Fernanda

{"title":"Potensi Antimikroba Ekstrak Ethanol Ganoderma lucidum Menggunakan Metode Bioautografi terhadap Bakteri Escherichia coli dan Bacillus subtillis","authors":"Tri Puji Lestari Sudarwati, M. Fernanda","doi":"10.53342/PHARMASCI.V6I1.212","DOIUrl":"https://doi.org/10.53342/PHARMASCI.V6I1.212","url":null,"abstract":"Potensi antibakteri ekstrak ethanol jamur lingzhi (Ganoderma lucidum) menggunakan metode analisis KLT bioautografi terhadap Escherichia coli dan Bacillus subtillis sebagai penelitian pendahuluan untuk mengetahui kandungan metabolit sekunder pada jamur lingzi. Soxhletasi merupakan metode untuk mengekstraksi serbuk jamur lingzhi menggunakan pelarut etanol. Bioautografi merupakan metode yang digunakan untuk mengetahui kandungan metabolit sekunder pada jamur lingzi dan potensi antibakteri. Konsentrasi yang digunakan yaitu: 2%, 4%, 6%, 8%dan 10%, dengan pengulangan sebanyak 5 kali. KLT bioautografi menggunakan n-butanol : Asam asetat glasial : Air (4:1:5) sebagai eluent. Analisis yang telah dilakukan menghasilkan 3 noda dengan Rf 0,5 dengan warna kuning, Rf 0,87 warna biru, Rf 0,93 warna coklat, dengan daerah hambatan pada noda coklat dengan Rf 0,93 merupakan senyawa triterpen. Hasil dari pengukuran nilai rata-rata zona hambat yang diperoleh terhadap bakteri E.coli adalah sebagai berikut, pada konsentrasi 2% 5,45 mm dengan kategori lemah, konsentrasi 4% 5,14 mm, konsentrasi 6% 5,48 mm, konsentrasi 8% 5,94 mm dan konsentrasi terbesar terdapat pada konsentrasi 10% 6,98 mm dengan kategori sedang. Pada bakteri Bakteri Bacillus subtillis konsentrasi 2% Sebesar 5,9 mm, Konsentrasi 4% Sebesar 6,34 mm, Konsentrasi 6% Sebesar 6,68 mm, Konsentrasi 8% Sebesar 7,88 mm, Dan Konsentrasi 10% Sebesar 8,6 mm dengan Kategori Sedang Maka dapat disimpulkan bahwa ekstrak jamur lingzhi memiliki aktivitas antibakteri terhadap bakteri Escherichia coli. Sehingga semakin besar konsentrasi yang digunakan, semakin besar pula aktivitasnya dalam menghambat pertumbuhan bakteri.","PeriodicalId":17631,"journal":{"name":"Journal Pharmasci (Journal of Pharmacy and Science)","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83652268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Optimization of Skin Moisturizer Formula Based on Fixed Oil (VCO, Olive Oil, and Jojoba Oil) 基于固定油(VCO、橄榄油、荷荷巴油)的保湿配方优化

Journal Pharmasci (Journal of Pharmacy and Science) Pub Date : 2021-01-01 DOI: 10.53342/pharmasci.v6i2.221

Dita Nurlita Rakhma, Yuyun Nailufa, Yuli Ainun Najih, Hery Wahjudi

{"title":"Optimization of Skin Moisturizer Formula Based on Fixed Oil (VCO, Olive Oil, and Jojoba Oil)","authors":"Dita Nurlita Rakhma, Yuyun Nailufa, Yuli Ainun Najih, Hery Wahjudi","doi":"10.53342/pharmasci.v6i2.221","DOIUrl":"https://doi.org/10.53342/pharmasci.v6i2.221","url":null,"abstract":"Currently, formulations of skin moisturizers are derived from natural compounds. Fixed oils are known to have compounds that potential to be developed as skin moisturizers based on emollient mechanism. Therefore, this study aims to determine the effect of oil type on the physical characteristics of skin moisturizer creams. In this study, a skin moisturizer cream was formulated using three types of fixed oils: VCO (F1), Olive Oil (F2), and Jojoba Oil (F3). All formulas were tested for physical characteristics of pH, cream type, viscosity, spreadability, and homogeneity. The test results show that all formulas appropriate to the skin pH range, have o/w type creams and homogeneous texture. In the results of the viscosity test, there was a significant difference (p<0.05) with the highest value of viscosity for F2 (16750 ± 250 cP) > F3 (14200 ± 346cP) > F1 (5833 ± 58 cP), while for spreadability test there were also significant differences (p<0.05) with the highest diameter for F1 (5.8 ± 0.1 cm) = F3 (5.7 ± 0.2 cm) > F2 (4.3 ± 0.2 cm). Based on the results, it can be concluded that the type of oil can affect the physical characteristics of the moisturizer formula. F1 and F3 have better physical characteristics than F2.","PeriodicalId":17631,"journal":{"name":"Journal Pharmasci (Journal of Pharmacy and Science)","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76316847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0