{"title":"抗逆转录病毒联合治疗与RSUD中HIV - TB患者CD4水平的关系","authors":"Jelly Permatasari, Indri Meirista, Hamira Bafadhal","doi":"10.53342/pharmasci.v6i2.198","DOIUrl":null,"url":null,"abstract":"The cases of Human Immunodeficiency Virus (HIV) infection are increasing every year. This case is a disease that is very rapidly transmitted throughout the world. HIV increases the risk of developing tuberculosis (TB) and conversely TB infection increases HIV progression. In 2017, it is estimated that 10 million people have HIV TB. Combination of antiretrovirals is the basis for the management of antiretroviral therapy for HIV / AIDS patients, because it can reduce resistance, suppress HIV replication effectively so that transmission, opportunistic infections and other complications. The purpose of this study was to determine the relationship between antiretroviral combinations and CD4 levels in outpatient HIV TB patients at RSUD H. Abdul Manap Jambi. This study is a retrospective cohort study using medical records of outpatient HIV TB patients at RSUD H. Abdul Manap Jambi based on inclusion and exclusion criteria. Based on research conducted on outpatient HIV TB patients at Abdul Manap Hospital, Jambi, it was found that there was no relationship between antiretroviral combinations and CD4 levels in HIV TB patients, marked by Asimp.Sig 0.778> 0.05.","PeriodicalId":17631,"journal":{"name":"Journal Pharmasci (Journal of Pharmacy and Science)","volume":"31 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Relations of Antiretroviral Combinations to CD4 Levels of HIV TB Patiens in RSUD H.Abdul Manap Jambi\",\"authors\":\"Jelly Permatasari, Indri Meirista, Hamira Bafadhal\",\"doi\":\"10.53342/pharmasci.v6i2.198\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The cases of Human Immunodeficiency Virus (HIV) infection are increasing every year. This case is a disease that is very rapidly transmitted throughout the world. HIV increases the risk of developing tuberculosis (TB) and conversely TB infection increases HIV progression. In 2017, it is estimated that 10 million people have HIV TB. Combination of antiretrovirals is the basis for the management of antiretroviral therapy for HIV / AIDS patients, because it can reduce resistance, suppress HIV replication effectively so that transmission, opportunistic infections and other complications. The purpose of this study was to determine the relationship between antiretroviral combinations and CD4 levels in outpatient HIV TB patients at RSUD H. Abdul Manap Jambi. This study is a retrospective cohort study using medical records of outpatient HIV TB patients at RSUD H. Abdul Manap Jambi based on inclusion and exclusion criteria. Based on research conducted on outpatient HIV TB patients at Abdul Manap Hospital, Jambi, it was found that there was no relationship between antiretroviral combinations and CD4 levels in HIV TB patients, marked by Asimp.Sig 0.778> 0.05.\",\"PeriodicalId\":17631,\"journal\":{\"name\":\"Journal Pharmasci (Journal of Pharmacy and Science)\",\"volume\":\"31 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-07-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal Pharmasci (Journal of Pharmacy and Science)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.53342/pharmasci.v6i2.198\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal Pharmasci (Journal of Pharmacy and Science)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.53342/pharmasci.v6i2.198","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
人类免疫缺陷病毒(HIV)感染的病例每年都在增加。这种病例是一种在世界范围内迅速传播的疾病。艾滋病毒增加了患结核病的风险,反过来,结核感染也增加了艾滋病毒的进展。2017年,估计有1000万人患有艾滋病毒结核病。联合使用抗逆转录病毒药物是对艾滋病毒/艾滋病患者进行抗逆转录病毒治疗的基础,因为它可以有效地减少耐药性,抑制艾滋病毒的复制,使其传播、机会性感染和其他并发症。本研究的目的是确定RSUD H. Abdul Manap Jambi门诊HIV结核病患者抗逆转录病毒联合治疗与CD4水平之间的关系。本研究是一项基于纳入和排除标准的回顾性队列研究,使用RSUD H. Abdul Manap Jambi门诊HIV结核病患者的医疗记录。根据Jambi Abdul Manap医院对门诊HIV结核病患者的研究,发现抗逆转录病毒联合治疗与HIV结核病患者CD4水平无相关性,其标志为asimpp . sig 0.778> 0.05。
Relations of Antiretroviral Combinations to CD4 Levels of HIV TB Patiens in RSUD H.Abdul Manap Jambi
The cases of Human Immunodeficiency Virus (HIV) infection are increasing every year. This case is a disease that is very rapidly transmitted throughout the world. HIV increases the risk of developing tuberculosis (TB) and conversely TB infection increases HIV progression. In 2017, it is estimated that 10 million people have HIV TB. Combination of antiretrovirals is the basis for the management of antiretroviral therapy for HIV / AIDS patients, because it can reduce resistance, suppress HIV replication effectively so that transmission, opportunistic infections and other complications. The purpose of this study was to determine the relationship between antiretroviral combinations and CD4 levels in outpatient HIV TB patients at RSUD H. Abdul Manap Jambi. This study is a retrospective cohort study using medical records of outpatient HIV TB patients at RSUD H. Abdul Manap Jambi based on inclusion and exclusion criteria. Based on research conducted on outpatient HIV TB patients at Abdul Manap Hospital, Jambi, it was found that there was no relationship between antiretroviral combinations and CD4 levels in HIV TB patients, marked by Asimp.Sig 0.778> 0.05.