Journal Pharmasci (Journal of Pharmacy and Science)最新文献

Antioxidant Avtivity Test of 50% Ethanol Extract of Rosemary Leaves (Rosmarinus officinalis L.) using DPPH Method 用 DPPH 法测试迷迭香叶（Rosmarinus officinalis L.）50% 乙醇提取物的抗氧化性

Journal Pharmasci (Journal of Pharmacy and Science) Pub Date : 2024-06-11 DOI: 10.53342/pharmasci.v9i1.391

G. G. Kusumo, Nia Dwi Wahyuning Arum, Mercyska Suryandari, Andhika Dwi Aristyawan

引用次数: 0

Overview of Community Knowledge about The Use of Antibotic in Blungkan Hamlet, Sendangrejo Village, Lamongan Sub-district, Lamongan District 拉蒙甘区拉蒙甘分区 Sendangrejo 村 Blungkan 小区社区对抗生素使用情况的了解概述

Journal Pharmasci (Journal of Pharmacy and Science) Pub Date : 2024-02-21 DOI: 10.53342/pharmasci.v9i1.422

Widi Ambar Pratiwi, A. L. Nasyanka

{"title":"Overview of Community Knowledge about The Use of Antibotic in Blungkan Hamlet, Sendangrejo Village, Lamongan Sub-district, Lamongan District","authors":"Widi Ambar Pratiwi, A. L. Nasyanka","doi":"10.53342/pharmasci.v9i1.422","DOIUrl":"https://doi.org/10.53342/pharmasci.v9i1.422","url":null,"abstract":"Antibiotics are medications that combat bacterial illnesses. There are several negative health outcomes associated with the current epidemic of antibiotic resistance, including higher rates of illness and death, higher healthcare expenditures, and treatment failures. In 2015, there were an increase of 50 million unnecessary antibiotic prescriptions (Unnescecery prescribing) from 150 million, and this number continues to increase every year. Thus, the number of bacteria that are resistant to antibiotics is increasing. This study aims to determine the extent of public awareness on the utilization of antibiotics in Dusun Blungkan, Sendangrejo village, Lamongan district. The design of this research is descriptive research and data collection using questionnaires with Cronbach's alpha value of 0.83 (>0.60) then the questionnaire is declared reliable that covers 7 domains of knowledge namely understanding antibiotics, antibiotic examples, antibiotics use, dosage, contraindications, side effects, and antibiotic resistance. The results showed that in Dusun Blungkan, Sendangrejo Village, Lamongan District, and Lamongan Province there are 21 (70%) people who are aware of the use of antibiotics. Out of 30 respondents, 21 people (70%) have sufficient knowledge, 7 people (23.3%) have less knowledge, and 2 people (6.7%) have good knowledge. Controlled use of antibiotics can prevent resistance. Therefore, accurate information about the importance of antibiotics and how to use antibiotics properly and correctly is needed, as well as more wisdom in using them to avoid unexpected side effects.","PeriodicalId":17631,"journal":{"name":"Journal Pharmasci (Journal of Pharmacy and Science)","volume":"20 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140442523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Study of Levofloxacin and Cefoperazone-Sulbactam Utilization Cost on Patients with Mild and Moderate Corona Virus Disease-2019 轻度和中度科罗娜病毒病患者的左氧氟沙星和头孢哌酮-舒巴坦使用成本研究-2019

Journal Pharmasci (Journal of Pharmacy and Science) Pub Date : 2024-01-30 DOI: 10.53342/pharmasci.v9i1.316

Dyah Ayu Listyaningrum, Intan Kurnia Permatasari

{"title":"Study of Levofloxacin and Cefoperazone-Sulbactam Utilization Cost on Patients with Mild and Moderate Corona Virus Disease-2019","authors":"Dyah Ayu Listyaningrum, Intan Kurnia Permatasari","doi":"10.53342/pharmasci.v9i1.316","DOIUrl":"https://doi.org/10.53342/pharmasci.v9i1.316","url":null,"abstract":"Covid-19 is a highly infectious disease caused by SARS Cov-2. Antibiotics are sometimes given as therapy to patients when there is a secondary bacterial infection. The purpose of this study was to determine the treatment costs associated with using antibiotics Levofloxacin and Cefoperazone Sulbactam for mild to moderate COVID-19 patients at Bhayangkara H.S Samsoeri Mertojoso Hospital in Surabaya. For mild COVID-19 patients who receive levofloxacin antibiotic therapy, the total cost of treatment is IDR. 66,648,632 with a length of stay of 9 days. For patients with moderate degrees of COVID-19, the total cost of treatment is Rp. 81,339,295 with 10 days of hospitalization. For mild COVID-19 patients who receive cefoperazone sulbactam antibiotic therapy, the total cost of treatment is IDR. 81,401,005 with a length of stay of 11 days. For patients with moderate degrees of COVID-19, the total medical costs are Rp. 71,613,107 with 9 days of hospitalization. Based on the evaluation of research results, mild COVID-19 patients can receive levofloxacin antibiotic therapy, while moderate COVID-19 patients can receive cefoperazone sulbactam antibiotic therapy because it is cheaper and results in a shorter length of stay.","PeriodicalId":17631,"journal":{"name":"Journal Pharmasci (Journal of Pharmacy and Science)","volume":"226 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140484945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Disposal of Drugs in Household Communities in Magetan District 马格丹县家庭社区的药物处置情况

Journal Pharmasci (Journal of Pharmacy and Science) Pub Date : 2024-01-29 DOI: 10.53342/pharmasci.v9i1.419

Vidya Kartikaningrum

引用次数: 0

Ethnopharmaceutical Study of Efficacious Plants As Medicine in Bollangi Hamlet, Pattallassang District, Gowa Regency 戈瓦县帕塔拉桑区博兰吉村药用植物的民族药学研究

Journal Pharmasci (Journal of Pharmacy and Science) Pub Date : 2024-01-29 DOI: 10.53342/pharmasci.v9i1.392

Neneng Wildayanti Putri, Sisilia Teresia Rosmala Dewi, Dwi Rachmawaty

{"title":"Ethnopharmaceutical Study of Efficacious Plants As Medicine in Bollangi Hamlet, Pattallassang District, Gowa Regency","authors":"Neneng Wildayanti Putri, Sisilia Teresia Rosmala Dewi, Dwi Rachmawaty","doi":"10.53342/pharmasci.v9i1.392","DOIUrl":"https://doi.org/10.53342/pharmasci.v9i1.392","url":null,"abstract":"Ethnopharmacy is the pharmaceutical science that studies using and treating medicinal plants from certain ethnic groups or ethnic groups. The people of Bollangi Hamlet, Pattallassang District, and Gowa Regency have been using medicinal plants to treat diseases for generations because they have access to treatment, such as the local health center, and the hospital is quite far away. This study aims to determine the types of plants and parts of plants that are used in traditional medicine, how to process them, how to use them, and types of plants that have the potential to be further studied for their bioactivity. This research uses a descriptive research type combining qualitative and quantitative methods. Qualitative research was conducted by way of interviews and experiences of respondents. Based on the research results, it is known that there are 20 types of plants used in traditional medicine. The processing methods are boiling, pounded, and consumed directly. The method of use is by drinking, smearing/pasting, eating/chewing, and plants that have the potential to be further studied for their bioactivity are Guava and Garlic.","PeriodicalId":17631,"journal":{"name":"Journal Pharmasci (Journal of Pharmacy and Science)","volume":"11 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140489126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of Vitamin C Levels in Rose Kombucha (Rosa hybrida) during Storage 贮藏期间玫瑰昆布茶（蔷薇杂交茶）中维生素 C 含量的比较

Journal Pharmasci (Journal of Pharmacy and Science) Pub Date : 2024-01-29 DOI: 10.53342/pharmasci.v9i1.389

Aulia Dyah Kartika, Lailatus Sa'diyah

引用次数: 0

Quantification of Total Phenol Concentration in Ethanol Extracts of Red and Black Betel Leaves Using UV-Vis Spectrophotometric 用紫外可见分光光度法量化红槟榔叶和黑槟榔叶乙醇提取物中的总酚浓度

Journal Pharmasci (Journal of Pharmacy and Science) Pub Date : 2024-01-22 DOI: 10.53342/pharmasci.v9i1.388

Safira Evani, Litalia Early Katreen Juniar, Meyke Herina Syafitri

{"title":"Quantification of Total Phenol Concentration in Ethanol Extracts of Red and Black Betel Leaves Using UV-Vis Spectrophotometric","authors":"Safira Evani, Litalia Early Katreen Juniar, Meyke Herina Syafitri","doi":"10.53342/pharmasci.v9i1.388","DOIUrl":"https://doi.org/10.53342/pharmasci.v9i1.388","url":null,"abstract":"Red betel (Piper crocatum Ruiz & Pav) and black betel leaves (Piper betle var. nigra) are plant varieties known for their medicinal properties. These plants have various contents including flavonoids, essential oils, tannins and polyphenols. The objective of this research is to ascertain the quantity of phenolic compounds present in ethanol extracts of red and black betel leaves. Determination of the levels of ethanol extracts of red and black betel leaves is done quantitatively by the folin-ciocalteu method. This method relies on the formation of a blue complex compound of of phosphomolybdat-phosphotungstat, generated by the reduction of phenolic compounds in an alkaline environment. The measurement is performed using uv-vis spectrophotometry. Gallic acid, derived from hydroxybenzoic acid and identified as a simple phenolic acid, is employed. This stable and pure polyphenolic compound is commonly found in almost all plants. Drawing conclusions from the study results, it can be affirmed that the average total phenol concentration of red betel was 31.87 GAE per gram extract and the average total phenol concentration of black betel leaves was 39.09 mg GAE per gram extract.","PeriodicalId":17631,"journal":{"name":"Journal Pharmasci (Journal of Pharmacy and Science)","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140499700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Stability of Serotonin Transporter Essential Amino Acid Complex with Curcumin and Demethoxycurcumin Compounds as Antidepressant Candidates Based on In Silico Test 基于硅学测试的血清素转运体必需氨基酸与姜黄素和去甲氧基姜黄素复合物作为抗抑郁候选药物的稳定性

Journal Pharmasci (Journal of Pharmacy and Science) Pub Date : 2024-01-22 DOI: 10.53342/pharmasci.v9i1.412

Farach Khanifah, Evi Puspita Sari, Gerry Nugraha

引用次数: 0

Antibiotic Drug Interaction in Prescribing Asthma Patients in One of the Clinics in the Surabaya Area 泗水地区一家诊所为哮喘患者开具处方时的抗生素药物相互作用

Journal Pharmasci (Journal of Pharmacy and Science) Pub Date : 2024-01-22 DOI: 10.53342/pharmasci.v9i1.351

Maya Herlinawaty, Ninik Mas Ulfa, Tri Doso Sapto Agus Priyono

{"title":"Antibiotic Drug Interaction in Prescribing Asthma Patients in One of the Clinics in the Surabaya Area","authors":"Maya Herlinawaty, Ninik Mas Ulfa, Tri Doso Sapto Agus Priyono","doi":"10.53342/pharmasci.v9i1.351","DOIUrl":"https://doi.org/10.53342/pharmasci.v9i1.351","url":null,"abstract":"Drug interactions are interactions that can occur if the effects of a drug are changed by other drugs, food or drinks. The aim of this research is to determine the potential for interactions between antibiotics and other drugs prescribed to asthma patients. Antibiotics are the drugs most widely used for infections caused by bacteria. Determining the mechanism of potential interactions between antibiotics and other drugs prescribed to asthma patients in this study using the Medscape application. The research results showed that there were 2044 prescriptions for the period Juli - December 2022, which provided the highest potential for drug interactions, namely interactions with pharmacokinetic mechanisms in the metabolic phase with 69 incidents (20.47%). Meanwhile, the highest level of severity was monitoring closely, 291 (86.35%) and those with the potential for serious interactions were 46 incidents (13.65%). In this research, the active role of Pharmacy Technicians and Pharmacists is needed to monitor the use of drugs that have the potential to cause drug interactions with prescribing doctors in the hope that undesirable drug interactions can be avoided.","PeriodicalId":17631,"journal":{"name":"Journal Pharmasci (Journal of Pharmacy and Science)","volume":"48 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140500532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of PEG 4000 in Co-processed Excipient using Melt Granulation Method on the Physical Characteristics of Chitosan Tablets in Mangrove Crab Shells (Scylla serrata) 熔融制粒法共处理辅料中的 PEG 4000 对红树螃蟹壳（Scylla serrata）壳聚糖片剂物理特性的影响

Journal Pharmasci (Journal of Pharmacy and Science) Pub Date : 2024-01-18 DOI: 10.53342/pharmasci.v9i1.350

Femiko Salsabil, Mariawati, Hilya Nur Imtihani

{"title":"The Effect of PEG 4000 in Co-processed Excipient using Melt Granulation Method on the Physical Characteristics of Chitosan Tablets in Mangrove Crab Shells (Scylla serrata)","authors":"Femiko Salsabil, Mariawati, Hilya Nur Imtihani","doi":"10.53342/pharmasci.v9i1.350","DOIUrl":"https://doi.org/10.53342/pharmasci.v9i1.350","url":null,"abstract":"Mangrove Crab (Scylla serrata) is an animal that likes to be consumed but its shell waste is underutilized. The shell contains chitosan which has many benefits, one of which can lower cholesterol levels. The combination of 2 or more excipients is called co-processed excipients which are then continued into tablets by direct compression. The aim of the study was to find out whether chitosan could be formalized into coprocessed tablets (lactose, primogel, and PEG 4000 7.5% & 15%) by direct compression method and the effect of differences in the characteristics of coprocessed and chitosan tablets with a ratio of PEG 4000 7.5% and 15 % as binder. The evaluation results showed that chitosan tablets fulfilled the requirements for the uniformity of weight, hardness, disintegration time (F1) tests, while they did not meet the requirements for the uniformity of tablet size, friability and disintegration times (F2) tests and the results of the coprocessing evaluation met specifications both F1 and F2, namely: particle size distribution, moisture content, flow rate, angle of repose (very good), compressibility index (adequate) and Hausner's ratio (very good). The evaluation results were then processed statistically using the SPSS application using the independent t-test method which showed that there was no significant difference in the effect of PEG 4000 7.5% and 15% as a binder on the characteristics of co-processed and chitosan tablets. Chitosan tablets from mangrove crab shells (Scylla serrata) cannot be formalized by direct compression with co-processing.","PeriodicalId":17631,"journal":{"name":"Journal Pharmasci (Journal of Pharmacy and Science)","volume":"28 16","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140504223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0