{"title":"Retrospective evaluation of the short-term response of human intravenous immunoglobulin therapy in the management of canine immune-mediated thrombocytopenia (2010–2015): 27 cases","authors":"Andrea Zoia DVM, MSc, PhD, DECVIM, Francesca Busato DVM, DECVIM, Michele Drigo DVM, PhD","doi":"10.1111/vec.13408","DOIUrl":"10.1111/vec.13408","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To describe the short-term response, early prognostic markers, and survival after treatment of canine immune-mediated thrombocytopenia (ITP) with human intravenous immunoglobulin (hIVIG) and methylprednisolone.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Design</h3>\u0000 \u0000 <p>Retrospective cohort study.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Settings</h3>\u0000 \u0000 <p>Private referral veterinary medical center.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Animals</h3>\u0000 \u0000 <p>Twenty-seven client-owned dogs with primary or secondary ITP.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Interventions</h3>\u0000 \u0000 <p>All dogs received 2 mg/kg IV methylprednisolone once daily and a single infusion of 5% hIVIG administered over 6–12 hours.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Measurements and Main Results</h3>\u0000 \u0000 <p>A substantial increase in platelet count within 60 ± 12 hours post-hIVIG infusion (T<sub>60</sub>) was observed in 19 of the 27 (70%) dogs with ITP (responders). Thirty-four variables, including serum immunoglobulin (Ig) G concentration 24 ± 12 hours post-hIVIG infusion (T<sub>24</sub>IgG) and increase in serum IgG concentration 24 ± 12 hours post-hIVIG infusion (T<sub>24</sub>Δ<sub>IgG</sub>), were compared between responders and nonresponders at 5 different time points. Mortality rates of responders and nonresponders were evaluated 14 days post-hIVIG infusion. Serum T<sub>24</sub>IgG and serum T<sub>24</sub>Δ<sub>IgG</sub> were both significantly higher at T<sub>60</sub> in responders. All responders were alive 14 days post-hIVIG infusion, and their mortality rate was significantly lower compared with nonresponders.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Responder dogs had an excellent 14-day survival rate. Serum T<sub>24</sub>IgG and serum T<sub>24</sub>Δ<sub>IgG</sub> concentrations accurately predicted response status at 60 hours post-hIVIG infusion.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17603,"journal":{"name":"Journal of veterinary emergency and critical care","volume":"34 5","pages":"465-477"},"PeriodicalIF":1.1,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141735853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of the implementation, frequency of use, type, and impact of veterinary emergency service pause systems","authors":"Andrew Linklater DVM, DACVECC","doi":"10.1111/vec.13410","DOIUrl":"10.1111/vec.13410","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To determine the prevalence of veterinary emergency service pause systems (VESPSs) and describe aspects of implementation and perceived impact.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Design</h3>\u0000 \u0000 <p>Electronic questionnaire</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Setting</h3>\u0000 \u0000 <p>Membership of the Veterinary Emergency and Critical Care Society (VECCS).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Animals</h3>\u0000 \u0000 <p>None.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Interventions</h3>\u0000 \u0000 <p>None.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Measurement and Main Results</h3>\u0000 \u0000 <p>A questionnaire was distributed to 6176 VECCS members with 1168 responses. Seventy-six percent of the respondents were veterinarians. Ninety-one percent of respondents practice in the United States, with 74% of them working at 24/7 multispecialty practices. Eighty-seven percent of respondents indicated patient volume had increased, and 75% reported that a VESPS had been implemented between September 2020 and December 2021. Sixty-two percent reported that their emergency service had been paused or closed once per week or more. The top reasons for implementing a VESPS included excessive caseload and staffing shortages. A variety of methods were utilized to implement a pause. Sixty-nine percent reported their VESPS was less than ideal for effectiveness. Pause systems were reported to be highly supported by medical staff. Seventy-seven percent reported increased client frustration and complaints, and 57% reported staff were stressed from denying care. Of those who do not currently have a VESPS in place, 74% would prefer to have one.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>VESPSs were in widespread use at the time of this survey, and most have been implemented between September 2020 and December 2021. The majority of VESPSs were employed to mitigate increased caseload and staffing shortages. Although VESPSs are largely supported by medical staff, drawbacks may include staff stress and client frustrations, and improvements are warranted.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17603,"journal":{"name":"Journal of veterinary emergency and critical care","volume":"34 5","pages":"455-464"},"PeriodicalIF":1.1,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141735852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mallory V. Horridge DVM, Bridget M. Lyons VMD, DACVECC, Darko Stefanovski BS, MS, PhD, Deborah C. Silverstein BS, DVM, DACVECC
{"title":"Development of a novel scoring system to predict mortality in canine patients with infection","authors":"Mallory V. Horridge DVM, Bridget M. Lyons VMD, DACVECC, Darko Stefanovski BS, MS, PhD, Deborah C. Silverstein BS, DVM, DACVECC","doi":"10.1111/vec.13405","DOIUrl":"10.1111/vec.13405","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To develop a novel illness severity scoring system to identify canine patients with infection that are at higher risk of mortality.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Key Findings</h3>\u0000 \u0000 <p>Mentation (Modified Glasgow Coma Scale and the Acute Patient Physiologic and Laboratory Evaluation mentation score), heart rate, pH, P<sub>v</sub><span>co</span><sub>2</sub>, potassium, and total plasma protein were found to be associated with mortality on univariate analysis. Logistic regression found that mentation, heart rate, and P<sub>v</sub><span>co</span><sub>2</sub> combined to form the following score: [(100 × mentation score) + (3 × heart rate) + (10 × P<sub>v</sub><span>co</span><sub>2</sub>], which was predictive of mortality (area under the receiver operating characteristic curve: 0.88). A cutoff of 900 provided a sensitivity of 80% and a specificity of 80%. If the cutoff was changed to 800, the sensitivity was 100% and the specificity was 50%.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Significance</h3>\u0000 \u0000 <p>A novel scoring system was developed to predict mortality in hospitalized dogs with confirmed or suspected infection. Further prospective evaluation in a larger patient cohort is necessary to validate this score.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17603,"journal":{"name":"Journal of veterinary emergency and critical care","volume":"34 4","pages":"412-416"},"PeriodicalIF":1.1,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141636043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Manju Gauri Kunchur BVSc, MS, Teri Jo Mauch MD, PhD, FAAP, FASN, Max Parkanzky DVM, MS, DACVIM, Louisa J. Rahilly DVM, DACVECC
{"title":"A review of renal tubular acidosis","authors":"Manju Gauri Kunchur BVSc, MS, Teri Jo Mauch MD, PhD, FAAP, FASN, Max Parkanzky DVM, MS, DACVIM, Louisa J. Rahilly DVM, DACVECC","doi":"10.1111/vec.13407","DOIUrl":"10.1111/vec.13407","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To review the current scientific literature on renal tubular acidosis (RTA) in people and small animals, focusing on diseases in veterinary medicine that result in secondary RTA.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Data Sources</h3>\u0000 \u0000 <p>Scientific reviews and original research publications on people and small animals focusing on RTA.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Summary</h3>\u0000 \u0000 <p>RTA is characterized by defective renal acid–base regulation that results in normal anion gap hyperchloremic metabolic acidosis. Renal acid–base regulation includes the reabsorption and regeneration of bicarbonate in the renal proximal tubule and collecting ducts and the process of ammoniagenesis. RTA occurs as a primary genetic disorder or secondary to disease conditions. Based on pathophysiology, RTA is classified as distal or type 1 RTA, proximal or type 2 RTA, type 3 RTA or carbonic anhydrase II mutation, and type 4 or hyperkalemic RTA. Fanconi syndrome comprises proximal RTA with additional defects in proximal tubular function. Extensive research elucidating the genetic basis of RTA in people exists. RTA is a genetic disorder in the Basenji breed of dogs, where the mutation is known. Secondary RTA in human and veterinary medicine is the sequela of diseases that include immune-mediated, toxic, and infectious causes. Diagnosis and characterization of RTA include the measurement of urine pH and the evaluation of renal handling of substances that should affect acid or bicarbonate excretion.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Commonality exists between human and veterinary medicine among the types of RTA. Many genetic defects causing primary RTA are identified in people, but those in companion animals other than in the Basenji are unknown. Critically ill veterinary patients are often admitted to the ICU for diseases associated with secondary RTA, or they may develop RTA while hospitalized. Recognition and treatment of RTA may reverse tubular dysfunction and promote recovery by correcting metabolic acidosis.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17603,"journal":{"name":"Journal of veterinary emergency and critical care","volume":"34 4","pages":"325-355"},"PeriodicalIF":1.1,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141636042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Briana M. McConnell DVM, Yonaira Cortes DVM, DACVECC, Dennis Bailey DVM, DACVIM
{"title":"Retrospective evaluation of shock index and mortality in dogs with head trauma (2015–2020): 86 cases","authors":"Briana M. McConnell DVM, Yonaira Cortes DVM, DACVECC, Dennis Bailey DVM, DACVIM","doi":"10.1111/vec.13411","DOIUrl":"10.1111/vec.13411","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To assess the relationship between shock index (SI) and mortality in dogs with head trauma (HT). A secondary objective was to compare SI with the animal trauma triage (ATT) score and Modified Glasgow Coma Scale (MCGS) score in HT cases. A tertiary aim was to assess if SI is predictive of survival to discharge or improvement in presenting neurologic signs.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Design</h3>\u0000 \u0000 <p>Retrospective study from January 2015 to December 2020.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Setting</h3>\u0000 \u0000 <p>Tertiary referral level II veterinary trauma center.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Animals</h3>\u0000 \u0000 <p>Eighty-six dogs with evidence of HT presenting through emergency for various traumas compared to 60 healthy control dogs.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Measurements and Main Results</h3>\u0000 \u0000 <p>SI was calculated using the quotient of heart rate over systolic blood pressure measured on presentation. SI was significantly higher in HT patients than healthy controls (<i>P</i> = 0.0019). SI was not significantly different between traumatic brain injury dogs that died or were euthanized and HT dogs that lived until the time of discharge (<i>P</i> = 0.98). SI was not significantly different between HT dogs that were neurologically normal at the time of discharge and HT dogs that were static or improved but not normal neurologically at the time of discharge (<i>P</i> = 0.84). In HT dogs, SI did not correlate with ATT score (<i>P</i> = 0.16) or MGCS score (<i>P</i> = 0.75). There was no significant difference in SI and length of hospitalization until death or discharge (<i>P</i> = 0.78).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>SI was significantly higher in HT patients compared to control patients. Interestingly, SI was not correlated with ATT score or MGCS score. The use of SI in HT patients warrants further investigation to assess the efficacy in predicting mortality.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17603,"journal":{"name":"Journal of veterinary emergency and critical care","volume":"34 4","pages":"387-392"},"PeriodicalIF":1.1,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141636044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of a cell salvage device on blood transfusions to dogs undergoing surgery at a referral veterinary hospital","authors":"Núria Comas Collgros LV, Vasilis Zapridis DVM, Janet Diana Godolphin BSc, PhD, Nicholas Bacon MA, VetMB, DECVS, DACVS","doi":"10.1111/vec.13403","DOIUrl":"10.1111/vec.13403","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To determine the number of homologous blood transfusions received by canine surgical patients after introducing a cell salvage device (CSD), trends in surgeries requiring blood transfusion, and the incidence of transfusion reactions.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Study Design</h3>\u0000 \u0000 <p>Retrospective study.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Setting</h3>\u0000 \u0000 <p>Single referral hospital.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Animals</h3>\u0000 \u0000 <p>All dogs having surgery at a single center (November 2015 to February 2021).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Interventions</h3>\u0000 \u0000 <p>Medical records of dogs having surgical treatment, including those that received either an autologous or homologous blood transfusion, were reviewed. The surgical patients were the baseline population, and the 2 transfusion groups were compared within this population to analyze the trends.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Main Results</h3>\u0000 \u0000 <p>A total of 37 and 86 dogs received autologous and homologous blood transfusions, respectively. There was an upward trend in the number of total monthly blood transfusions. No significant increase in the monthly number of homologous transfusions was observed before or after acquisition of the CSD. There was also an upward trend in total monthly surgeries, including those with higher risks of hemorrhage. Dogs receiving homologous blood transfusions had a higher incidence of clinical signs consistent with transfusion reactions (6.98%).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>An upward trend in autologous blood transfusions was seen with the introduction of a CSD. Hospitals with large surgical caseloads at high risk of hemorrhage may see a decreased need for outsourced blood products with the use of the CSD. The device can lead to a more responsible use of an increasingly scarce resource and decrease the risk of a blood transfusion reaction in dogs.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17603,"journal":{"name":"Journal of veterinary emergency and critical care","volume":"34 4","pages":"376-386"},"PeriodicalIF":1.1,"publicationDate":"2024-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141545630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daniel S. Gordon DVM, MS, DACVECC, Cathy E. Langston DVM, DACVIM
{"title":"Effective removal of gadolinium with hemodialysis in a dog with severe acute on chronic kidney injury","authors":"Daniel S. Gordon DVM, MS, DACVECC, Cathy E. Langston DVM, DACVIM","doi":"10.1111/vec.13404","DOIUrl":"10.1111/vec.13404","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To describe the use of intermittent hemodialysis (IHD) to remove gadolinium (28.1 mg/kg dose) in a dog with severe kidney disease.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Summary</h3>\u0000 \u0000 <p>A 12-year-old neutered female Yorkshire Terrier presented with severe acute-on-chronic kidney injury and concurrent neurological signs. The dog received extracorporeal therapy as part of management. Uremia improved after hemodialysis, but central nervous system signs persisted; therefore, a contrast-enhanced magnetic resonance imaging was performed, immediately followed by IHD. Two IHD treatments with a low-flux dialyzer were performed 1.5 and 25.75 hours after administration of gadolinium, with almost complete removal of gadolinium. More than 96% of gadolinium was removed with a single treatment.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> New or Unique Information Provided</h3>\u0000 \u0000 <p>Extracorporeal therapy is effective at removing gadolinium-based chelated contrast agents and could be considered if magnetic resonance imaging is indicated in a patient with substantial kidney impairment. Alternatively, newer contrast agents that have been deemed safer in this patient population could be used.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17603,"journal":{"name":"Journal of veterinary emergency and critical care","volume":"34 4","pages":"406-411"},"PeriodicalIF":1.1,"publicationDate":"2024-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141545629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sabrina N. Hoehne Dr med vet, DACVECC, DECVECC, Kate Hopper BVSc, PhD, DACVECC, Marlis L. Rezende DVM, PhD, DACVAA, Angela Borchers Dr med vet, DVM, DACVIM, DACVECC, Steven E. Epstein DVM, DACVECC
{"title":"Serial paired arterial and jugular venous point-of-care values in dogs undergoing manual basic life support","authors":"Sabrina N. Hoehne Dr med vet, DACVECC, DECVECC, Kate Hopper BVSc, PhD, DACVECC, Marlis L. Rezende DVM, PhD, DACVAA, Angela Borchers Dr med vet, DVM, DACVIM, DACVECC, Steven E. Epstein DVM, DACVECC","doi":"10.1111/vec.13406","DOIUrl":"10.1111/vec.13406","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To evaluate differences in point-of-care (POC) variables obtained from arterial and jugular venous blood in dogs undergoing manual basic life support (BLS) and report changes over time.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Design</h3>\u0000 \u0000 <p>Experimental study.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Setting</h3>\u0000 \u0000 <p>Small animal research facility.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Animals</h3>\u0000 \u0000 <p>Twenty-four purpose-bred research dogs.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Interventions</h3>\u0000 \u0000 <p>Dogs were anesthetized, and arterial catheters were placed before euthanasia. One minute after cardiopulmonary arrest, BLS consisting of manual chest compressions and ventilation delivered via endotracheal intubation, face mask, mouth-to-nose, or no ventilation was initiated. Paired arterial and jugular venous blood samples were obtained for POC testing before euthanasia (<i>T</i><sub>0</sub>), at 3 minutes (<i>T</i><sub>3</sub>), and at 6 minutes (<i>T</i><sub>6</sub>) into BLS.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Measurements and Main Results</h3>\u0000 \u0000 <p>The association of POC variables with arterial or venous sample type while controlling for type of ventilation and sampling timepoint was determined using a generalized linear mixed model. Variables obtained from arterial and venous blood samples were compared over time using repeated measures ANOVA or Friedman test. Pa<span>o</span><sub>2</sub>, anion gap, potassium, chloride, glucose concentration, and PCV were significantly higher in arterial blood samples compared with venous samples (<i>P</i> < 0.03). By <i>T</i><sub>6</sub>, arterial glucose concentration, arterial and venous base excess, venous pH, and plasma lactate, potassium, creatinine, bicarbonate, and sodium concentrations were significantly increased, and arterial and venous P<span>o</span><sub>2</sub>, ionized calcium concentration, PCV, and total plasma protein concentration were significantly decreased from <i>T</i><sub>0</sub> (<i>P</i> < 0.05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Although statistically significant, arteriovenous differences and changes in POC blood variables during BLS were small and not clinically relevant over time. Given the challenges of arterial blood sampling, it may be reasonable to pursue venous blood sampling during CPR. Further studies in dogs undergoing BLS and advanced life support are needed to better understand the potential clinical r","PeriodicalId":17603,"journal":{"name":"Journal of veterinary emergency and critical care","volume":"34 4","pages":"368-375"},"PeriodicalIF":1.1,"publicationDate":"2024-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141545631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marie E. Kerl DVM, MPH, MBA, Diplomate, ACVIM (SAIM) ACVECC, Nancy Rinkardt DVM, DVSc, Diplomate, ACVIM (SAIM), Scott Shaw DVM, Diplomate, ACVECC
{"title":"In memoriam for Dr. Kari Elaine Moore","authors":"Marie E. Kerl DVM, MPH, MBA, Diplomate, ACVIM (SAIM) ACVECC, Nancy Rinkardt DVM, DVSc, Diplomate, ACVIM (SAIM), Scott Shaw DVM, Diplomate, ACVECC","doi":"10.1111/vec.13402","DOIUrl":"10.1111/vec.13402","url":null,"abstract":"<p></p><p>On April 30, 2024, fellow Veterinary Emergency and Critical Care diplomate Dr. Kari Moore lost her valiant 18-month-long battle with T-cell prolymphocytic leukemia, and we lost a great advocate for promoting the highest standards of veterinary care for patients, clients, and the veterinary medical team.</p><p>Kari obtained her Doctor of Veterinary Medicine from Texas A&M University in 1994 and completed a rotating internship in small animal medicine and surgery at Rowley Memorial Animal Hospital. Following 2 years in general practice in Dallas, Kari completed a residency in Small Animal Emergency and Critical Care at Tufts University from 1997 to 2000 and became board-certified by the American College of Veterinary Emergency and Critical Care. Kari was a staff veterinarian at Angell Memorial Animal Hospital from 2000 to 2001 and then joined VCA Veterinary Referral Associates (VCA VRA) in Gaithersburg Maryland where she was the Intern and Resident Director and established an emergency practice before relocating to California in 2005. Kari served as Regional Medical Director from 2005 to 2007 with responsibility for 39 hospitals. In 2007, Kari became the medical director and intern director of VCA Sacramento Veterinary Referral Center (VCA SVRC), a position that she held until 2016 when she resumed a full-time role as Regional Medical Director with responsibility for 32 specialty and general practice hospitals in Northern California, Hawaii, and Colorado. Kari also was passionate about veterinary rehabilitation and became certified in animal rehabilitation.</p><p>Kari was a strong advocate for teaching throughout her career. As a first-year resident, she went out of her way to teach students, interns, and residents, and her contributions continued through her time at Angell Memorial, VCA VRA, and on the west coast. Kari was committed to nurturing the internship program in her home hospital of VCA SVRC as well as her other specialty hospitals in California, Colorado, and Hawaii. Kari also guided other specialists in her hospitals about their expectations to teach and mentor as a part of their work commitment.</p><p>Kari was deeply respected as a member of the VCA Regional Medical Director team.</p><p>She stood out as a competent and caring leader for her hospitals through being a person of “quiet strength.” She built trusting relationships with her hospital teams through frequent visits, always focusing on quality improvement and support no matter the size of the hospital. Leading and growing specialty hospitals can be challenging, but Kari's expertise and talent in this area were unparalleled. Her knowledge made her a trusted advisor for evaluating new equipment and innovations. She was also resourceful, quickly finding novel ways to help her hospitals manage communications and patient care challenges during the COVID-19 pandemic. In her mission to help more animals, Kari guided her hospitals through multiple wildfire disaster respons","PeriodicalId":17603,"journal":{"name":"Journal of veterinary emergency and critical care","volume":"34 4","pages":"417-418"},"PeriodicalIF":1.1,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/vec.13402","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141536091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction to “Evaluating the efficacy of shelf stable blood products for resuscitation in a canine hemorrhagic shock model”","authors":"","doi":"10.1111/vec.13401","DOIUrl":"10.1111/vec.13401","url":null,"abstract":"<p>Abstracts from the International Veterinary Emergency and Critical Care Symposium, the European Veterinary Emergency and Critical Care Annual Congress, and the ACVECC VetCOT Veterinary Trauma & Critical Care Conference 2023. 2023. <i>J Vet Emerg Crit Care</i>., 33: S1-S1. https://doi.org/10.1111/vec.13338</p><p>In the Abstracts Supplement published in September 2023, the abstract cited above had an omission in the authorship list.</p><p>The correct authorship is:</p><p>Ryan M, Ford R, Hall KE, Guillaumin J, Venn EC, Edwards TH, Hoareau GL</p>","PeriodicalId":17603,"journal":{"name":"Journal of veterinary emergency and critical care","volume":"34 4","pages":"419"},"PeriodicalIF":1.1,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/vec.13401","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141679826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}