Journal of veterinary emergency and critical care最新文献

{"title":"Successful Use of High-Flow Nasal Cannula Oxygen Therapy in Three Dogs With Carbon Monoxide Poisoning","authors":"Lauren Robertson,&nbsp;Haley Coughlin,&nbsp;Jiwoong Her","doi":"10.1111/vec.70083","DOIUrl":"10.1111/vec.70083","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To report the use of high-flow nasal cannula oxygen therapy (HFNOT) in three dogs with carbon monoxide poisoning resulting from smoke inhalation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Series Summary</h3>\u0000 \u0000 <p>Three dogs were presented to the emergency room with carbon monoxide poisoning associated with house fires. Blood CO-oximetry at the time of presentation confirmed markedly increased carboxyhemoglobin levels. The dogs were treated with 4–7 h of HFNOT to eliminate carboxyhemoglobin. The calculated half-lives of carboxyhemoglobin during HFNOT for Dogs 1, 2, and 3 were 79, 86, and 77 min, respectively. All three dogs survived to discharge, and no delayed complications of carbon monoxide poisoning were reported.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> New or Unique Information Provided</h3>\u0000 \u0000 <p>To the authors’ knowledge, this is the first case series of dogs treated with HFNOT for carbon monoxide poisoning. HFNOT was shown to be effective at removing carbon monoxide, reducing the half-life of carboxyhemoglobin from 77 to 86 min. The half-life of carboxyhemoglobin and the effectiveness of HFNOT should be further investigated in a larger sample of dogs.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17603,"journal":{"name":"Journal of veterinary emergency and critical care","volume":"36 1","pages":"101-106"},"PeriodicalIF":1.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12950933/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145999751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reviewer List for 2025","authors":"","doi":"10.1111/vec.70098","DOIUrl":"10.1111/vec.70098","url":null,"abstract":"&lt;p&gt;On behalf of the countless individuals tasked with making the &lt;i&gt;Journal of Veterinary Emergency and Critical Care&lt;/i&gt; a success, we wish to sincerely thank all of our reviewers who contributed to the success of the journal in 2025. Your contributions to the peer review process are invaluable in our pursuit of excellence. We would like to especially thank those reviewers who reviewed five or more manuscripts this year—your dedication to the journal is commendable. The number of reviews performed is noted in parentheses.&lt;/p&gt;&lt;p&gt;Mays, Erin (12)&lt;/p&gt;&lt;p&gt;Cook, Simon (10)&lt;/p&gt;&lt;p&gt;Donati, Pablo (10)&lt;/p&gt;&lt;p&gt;Walton, Rebecca L. (10)&lt;/p&gt;&lt;p&gt;Hezzell, Melanie Jane (9)&lt;/p&gt;&lt;p&gt;Humm, Karen (9)&lt;/p&gt;&lt;p&gt;Nash, Katherine (9)&lt;/p&gt;&lt;p&gt;Rozanski, Elizabeth (9)&lt;/p&gt;&lt;p&gt;Her, Jiwoong (8)&lt;/p&gt;&lt;p&gt;Monnig, Andrea (8)&lt;/p&gt;&lt;p&gt;Blois, Shauna (7)&lt;/p&gt;&lt;p&gt;Hopper, Kate (7)&lt;/p&gt;&lt;p&gt;Jandrey, Karl (7)&lt;/p&gt;&lt;p&gt;Jones, Nadine (7)&lt;/p&gt;&lt;p&gt;Marshall, Hannah (7)&lt;/p&gt;&lt;p&gt;Turley, Kelsey A. (7)&lt;/p&gt;&lt;p&gt;Bishop, Rebecca (6)&lt;/p&gt;&lt;p&gt;Brainard, Benjamin (6)&lt;/p&gt;&lt;p&gt;Cuddy, Lindsay (6)&lt;/p&gt;&lt;p&gt;Epstein, Steven (6)&lt;/p&gt;&lt;p&gt;Keir, Iain (6)&lt;/p&gt;&lt;p&gt;Klainbart, Sigal (6)&lt;/p&gt;&lt;p&gt;Lynch, Alex M. (6)&lt;/p&gt;&lt;p&gt;O'Kelley, Benjamin (6)&lt;/p&gt;&lt;p&gt;Pfaff, Alexandra (6)&lt;/p&gt;&lt;p&gt;Wismer, Tina (6)&lt;/p&gt;&lt;p&gt;Zeiler, Gareth E. (6)&lt;/p&gt;&lt;p&gt;Aumann, Samantha (5)&lt;/p&gt;&lt;p&gt;Bracker, Kiko (5)&lt;/p&gt;&lt;p&gt;Chan, Dan (5)&lt;/p&gt;&lt;p&gt;Dicker, Samuel Avram (5)&lt;/p&gt;&lt;p&gt;Hovda, Lynn (5)&lt;/p&gt;&lt;p&gt;Jagodich, Tiffany (5)&lt;/p&gt;&lt;p&gt;Lyons, Bridget (5)&lt;/p&gt;&lt;p&gt;Pigott, Armi (5)&lt;/p&gt;&lt;p&gt;Reinhart, Jennifer M. (5)&lt;/p&gt;&lt;p&gt;Stastny, Tereza (5)&lt;/p&gt;&lt;p&gt;Wardrop, K. Jane (5)&lt;/p&gt;&lt;p&gt;Zersen, Kristin (5)&lt;/p&gt;&lt;p&gt;Boag, Alisdair (4)&lt;/p&gt;&lt;p&gt;Boag, Amanda (4)&lt;/p&gt;&lt;p&gt;Bowen, Caitlin (4)&lt;/p&gt;&lt;p&gt;Briganti, Angela (4)&lt;/p&gt;&lt;p&gt;Conner, Bobbi (4)&lt;/p&gt;&lt;p&gt;Dörfelt, René (4)&lt;/p&gt;&lt;p&gt;Downing, Frances (4)&lt;/p&gt;&lt;p&gt;Dupanloup, Adrien (4)&lt;/p&gt;&lt;p&gt;Fischer, Andrea (4)&lt;/p&gt;&lt;p&gt;Fletcher, Dan (4)&lt;/p&gt;&lt;p&gt;Guillaumin, Julien (4)&lt;/p&gt;&lt;p&gt;Halpin, Rachel (4)&lt;/p&gt;&lt;p&gt;Hasegawa, Daisuke (4)&lt;/p&gt;&lt;p&gt;Hemmelgarn, Carey Ann (4)&lt;/p&gt;&lt;p&gt;Hoehne, Sabrina (4)&lt;/p&gt;&lt;p&gt;Hurn, Simon (4)&lt;/p&gt;&lt;p&gt;Jones, Jessica (4)&lt;/p&gt;&lt;p&gt;Judy, Annalisa (4)&lt;/p&gt;&lt;p&gt;Kaplan, Amy (4)&lt;/p&gt;&lt;p&gt;Kelley, Morgan (4)&lt;/p&gt;&lt;p&gt;Knipe, Marguerite F. (4)&lt;/p&gt;&lt;p&gt;Levy, Nyssa (4)&lt;/p&gt;&lt;p&gt;Molitoris, Amy (4)&lt;/p&gt;&lt;p&gt;Munsterman, Amelia (4)&lt;/p&gt;&lt;p&gt;Odunayo, Adesola (4)&lt;/p&gt;&lt;p&gt;Oricco, Stefano (4)&lt;/p&gt;&lt;p&gt;Partlow, Jessica (4)&lt;/p&gt;&lt;p&gt;Quandt, Jane (4)&lt;/p&gt;&lt;p&gt;Safrany, Ben (4)&lt;/p&gt;&lt;p&gt;Sigrist, Nadja (4)&lt;/p&gt;&lt;p&gt;Turner, Kate (4)&lt;/p&gt;&lt;p&gt;Ueda, Yu (4)&lt;/p&gt;&lt;p&gt;Wheeler, Lance R. (4)&lt;/p&gt;&lt;p&gt;Wilkins, Pamela A. (4)&lt;/p&gt;&lt;p&gt;Wright, Ian (4)&lt;/p&gt;&lt;p&gt;Zoff, Aurora (4)&lt;/p&gt;&lt;p&gt;Alwood, Ames (3)&lt;/p&gt;&lt;p&gt;Asokan, Vibha (3)&lt;/p&gt;&lt;p&gt;Bae, Seulgi (3)&lt;/p&gt;&lt;p&gt;Bateman, Shane (3)&lt;/p&gt;&lt;p&gt;Bates, Nicola (3)&lt;/p&gt;&lt;p&gt;Beal, Matthew (3)&lt;/p&gt;&lt;p&gt;Bell, Amy (3)&lt;/p&gt;&lt;p&gt;Birkbeck, Rachael (3)&lt;/p&gt;&lt;p&gt;Blong, April (3)&lt;/p&gt;&lt;p&gt;Boller, Manuel (3)&lt;/p&gt;&lt;p&gt;Bucknoff, Melissa (3)&lt;/p&gt;&lt;p&gt;Burchell, Richard (3)&lt;/p&gt;&lt;p&gt;Camacho, Fernanda (3)&lt;/p&gt;&lt;p&gt;Cazzolli, Dava (3)&lt;/p&gt;&lt;p&gt;Daly, Meredith (3)&lt;/p&gt;&lt;p&gt;Davidow, Elizabeth (3)&lt;/p&gt;&lt;p&gt;Destefano, Ian M. (3)&lt;/p&gt;&lt;p&gt;Farrell, Kate (3)&lt;/p&gt;&lt;p&gt;Forbes, Jethro (3)&lt;/p&gt;&lt;p&gt;García San José, Paula (4)&lt;/p&gt;&lt;p&gt;Goodnight, Michelle (3)&lt;/p&gt;&lt;p&gt;Julie","PeriodicalId":17603,"journal":{"name":"Journal of veterinary emergency and critical care","volume":"36 1","pages":"9-12"},"PeriodicalIF":1.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/vec.70098","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146151400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Issue Information - Prelim","authors":"","doi":"10.1111/vec.70097","DOIUrl":"https://doi.org/10.1111/vec.70097","url":null,"abstract":"","PeriodicalId":17603,"journal":{"name":"Journal of veterinary emergency and critical care","volume":"36 1","pages":"1-4"},"PeriodicalIF":1.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/vec.70097","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147562246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Novel Equine F[abʹ]2 Veterinary Antivenom for North American Viperid Snake Envenomation Demonstrates Efficacy by Rapid Serum Venom Removal and Improvement in Snakebite Severity Score","authors":"Sarah E. Carotenuto,&nbsp;Gena Broussard,&nbsp;Gerad A. Fox,&nbsp;William K. Hayes","doi":"10.1111/vec.70082","DOIUrl":"10.1111/vec.70082","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To assess the efficacy of a new equine F[abʹ]₂ antivenom (US Department of Agriculture code 6101.05) in removing serum venom and lowering the snakebite severity score (SSS) in animals suffering from naturally occurring viperid envenomation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Design</h3>\u0000 \u0000 <p>Retrospective study, April 2020 to October 2021.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Setting</h3>\u0000 \u0000 <p>Veterinary hospitals across four North American regions.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Animals</h3>\u0000 \u0000 <p>Twenty-two dogs, one cat, and one horse.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Interventions</h3>\u0000 \u0000 <p>All patients received the new antivenom intravenously and were assessed for clinical response. Most dogs required one vial for clinical control of signs.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Measurements and Main Results</h3>\u0000 \u0000 <p>Among the dogs and cats with detectable initial serum venom, 94.4% showed a strong response to antivenom administration, with a reduction in serum venom ranging from 94% to &gt;99% at 2 h. Animals that experienced a 90% reduction of serum venom within 2 h greatly exceeded the 0% expected of an ineffective antivenom. The canine and feline SSS improved relative to the initial SSS at 2, 6, and 12 h in 57.9%, 77.8%, and 90.9% of cases, respectively. A favorable reduction in SSS was also appreciated in the single horse in the study.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>In the canine, feline, and equine cases of North American viperid envenomation studied, antivenom 6101.05 adequately removed serum venom and lowered the SSS.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17603,"journal":{"name":"Journal of veterinary emergency and critical care","volume":"36 1","pages":"45-55"},"PeriodicalIF":1.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146055290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retrospective Evaluation of Admission Variables Associated With Outcome in Dogs With Bite Wound Trauma (12,412 cases): An ACVECC-VetCOT Registry Study","authors":"Margaret E. Cook,&nbsp;Kelsea E. Guest,&nbsp;Michael L. Creutzinger,&nbsp;Erica L. Reineke,&nbsp;Ashlei Tinsley,&nbsp;Kelly E. Hall","doi":"10.1111/vec.70092","DOIUrl":"10.1111/vec.70092","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Objective&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;To describe admission variables in dogs with bite wound trauma and to evaluate the relationship of these variables with the type of bite wound (penetrating, blunt, combination) and survival outcome.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Design&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Retrospective evaluation of multi-institutional veterinary trauma registry data on dogs presenting with bite wound trauma.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Setting&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Veterinary Committee on Trauma-identified Veterinary Trauma Centers (VTCs).&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Animals&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;A total of 12,412 dogs with bite wound trauma presented to VTCs with data entered in the Veterinary Committee on Trauma registry from April 1, 2017, to December 31, 2021.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Interventions&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;None&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Measurements and Main Results&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Admission variables and outcome were evaluated for dogs suffering from penetrating bite trauma (10,942/12,412; 88.16%), blunt bite trauma (479/12,412; 3.86%), and a combination of these (991/12,412; 7.98%). Among all groups, 95.06% (11,799/12,412) survived to discharge, 1.01% (125/12,412) died, and 3.93% (488/12,412) were euthanized. Patient sex (&lt;i&gt;p&lt;/i&gt; &lt; 0.001), modified Glasgow Coma Scale score (&lt;i&gt;p&lt;/i&gt; &lt; 0.001), Animal Trauma Triage score (&lt;i&gt;p&lt;/i&gt; &lt; 0.001), lactate concentration (&lt;i&gt;p&lt;/i&gt; &lt; 0.001), base excess (&lt;i&gt;p&lt;/i&gt; &lt; 0.001), blood glucose concentration (&lt;i&gt;p&lt;/i&gt; &lt; 0.001), ionized calcium concentration (&lt;i&gt;p&lt;/i&gt; &lt; 0.001), and PCV/total plasma protein concentration (&lt;i&gt;p&lt;/i&gt; &lt; 0.001/&lt;i&gt;p&lt;/i&gt; &lt; 0.001) were each associated with survival outcome. Head injury (&lt;i&gt;p&lt;/i&gt; &lt; 0.001) or spinal trauma (&lt;i&gt;p&lt;/i&gt; &lt; 0.001) at time of admission, or the requirement for blood product transfusion (&lt;i&gt;p&lt;/i&gt; &lt; 0.001), was associated with a negative survival outcome. Treatment by a Doctor of Veterinary Medicine prior to arrival to VTC was associated with survival. In multivariate analysis, higher body weight and surgical intervention were associated with survival. Older age and glucose dysregulation were associated with a negative survival outcome.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Conclusion&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Dogs sustaining bite wound trauma have an excellent prognosis for survival.","PeriodicalId":17603,"journal":{"name":"Journal of veterinary emergency and critical care","volume":"36 1","pages":"66-76"},"PeriodicalIF":1.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12950943/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146095021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Traumatic Endocardial Rupture Causing Bilateral Forelimb Arterial Thromboembolism in a Dog","authors":"Karla M. Fraga,&nbsp;Jack A. Lee,&nbsp;William E. Holl,&nbsp;Jose Cesar Menk,&nbsp;M. Ryan Smith","doi":"10.1111/vec.70079","DOIUrl":"10.1111/vec.70079","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To describe a case of traumatic endocardial rupture, without obvious clinical signs of cardiac injury, resulting in acute thrombosis of the forelimbs in a dog.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Summary</h3>\u0000 \u0000 <p>A young adult male German Shepherd Dog presented with vehicular polytrauma. The dog was diagnosed with hypovolemic shock and traumatic pneumothorax and was stabilized, having displayed no clinical indicators of cardiac dysfunction. For 10 days, the dog was treated with no complications in the hospital for wounds but presented again shortly after discharge with bilateral forelimb paraparesis determined likely to be due to thrombosis. The dog was euthanized, and the body was submitted for necropsy. A diagnosis was made of left atrial endocardial rupture with thrombosis, multifocal pulmonary bullae and contusions, and cutaneous abrasions, all secondary to trauma. Based on the dog's physical examination on secondary presentation and the necropsy findings of a thrombus adherent to a left atrial tear, it was suspected that one or more thrombus fragments dislodged and occluded the major supplying vessels of the forelimbs.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> New or Unique Information Provided</h3>\u0000 \u0000 <p>Blunt cardiac injury may occur without overt clinical manifestations of dysfunction and may lead to thrombosis and associated complications.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17603,"journal":{"name":"Journal of veterinary emergency and critical care","volume":"36 1","pages":"122-126"},"PeriodicalIF":1.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145999851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Urinary Tissue Inhibitor of Metalloproteinase-2 (TIMP-2), Insulin-Like Growth Factor–Binding Protein-7 (IGFBP-7), and Kidney Injury Molecule-1 (KIM-1) as Biomarkers for the Detection of Meloxicam-Induced Kidney Injury in Cats","authors":"Matthew K. Wun,&nbsp;Julianne K. Hwang,&nbsp;Nicolas F. Villarino","doi":"10.1111/vec.70076","DOIUrl":"10.1111/vec.70076","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To evaluate the concentration versus time course profiles of urinary tissue inhibitor of metalloproteinase-2 (TIMP-2), insulin-like growth factor–binding protein-7 (IGFBP-7), and kidney injury molecule-1 (KIM-1) during repeated administrations of meloxicam, and determine whether these profiles differ from saline-treated cats.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Design</h3>\u0000 \u0000 <p>Placebo-controlled experimental design performed in 2017.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Animals</h3>\u0000 \u0000 <p>Twelve healthy, adult, purpose-bred female cats.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Interventions</h3>\u0000 \u0000 <p>Cats were randomly allocated to control and treatment groups. Cats in the treatment group (<i>n</i> = 6) received meloxicam 0.3 mg/kg subcutaneously every 24 h for 31 days. Cats in the control group (<i>n</i> = 6) received saline (0.1 mL/kg subcutaneously).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Measurements and Main Results</h3>\u0000 \u0000 <p>Urinary TIMP-2, IGFBP-7, KIM-1, and creatinine were measured every 4–6 days for 31 days, along with serum creatinine. In the treatment group, cats were determined to have renal injury if at least one kidney had histopathological evidence of tubular damage, basement membrane damage, and/or interstitial inflammation. The urinary biomarker concentrations between control and renal injury groups were compared by calculating the area under the curve (AUC) for each biomarker normalized for urine creatinine (UC) concentration versus time course profile and reported as mean ± SE. The AUC values for the two groups were compared statistically using an unpaired, two-tailed <i>t</i>-test. The AUC for urinary IGFBP-7/UC was higher (<i>p</i> = 0.0152) in the treatment group (0.042 ± 0.0062) compared to the control group (0.02676 ± 0.0018). The AUC for urinary KIM-1/UC was higher (<i>p</i> = 0.0083) in the treatment group (0.034 ± 0.0055) compared to the control group (0.019 ± 0.0022). An increase in urinary TIMP-2 was detected in only 50% of the treatment group.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Urinary IGFBP-7 and KIM-1 increase in cats that develop acute kidney injury after repeated meloxicam administration. Further studies are needed before the clinical utility of these molecules as biomarkers for early acute kidney injury detection in cats can be determined.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17603,"journal":{"name":"Journal of veterinary emergency and critical care","volume":"36 1","pages":"39-44"},"PeriodicalIF":1.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145999746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful Functional Outcome in a Dog With Ventricular Tachycardia Treated With Antiarrhythmics, Cardioversion, Cardiopulmonary Resuscitation, and Intra-Arrest Lipid Emulsion","authors":"Lisa A. Murphy,&nbsp;Sonja S. Tjostheim,&nbsp;Rebecca L. Stepien","doi":"10.1111/vec.70089","DOIUrl":"10.1111/vec.70089","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To describe a case of successful CPR after prolonged cardiopulmonary arrest in a dog treated for refractory ventricular tachycardia (VT) with multiple antiarrhythmic medications and attempted electrical cardioversion, resulting in suspected lidocaine toxicosis necessitating intra-arrest IV lipid emulsion (ILE) administration.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Summary</h3>\u0000 \u0000 <p>A 6-month-old male intact American Cocker Spaniel was presented for evaluation of VT found on routine physical examination. A dilated cardiomyopathy phenotype was identified on echocardiography. The arrhythmia was refractory to therapy with lidocaine, magnesium sulfate, procainamide, and amiodarone. Subsequently, the dog was anesthetized for electrical cardioversion. The dog then developed ventricular fibrillation (VF), and CPR was performed per the contemporaneous Reassessment Campaign on Veterinary Resuscitation guidelines. Once the duration of VF exceeded 10 min, CPR was adjusted with a longer period of chest compressions before defibrillation. ILE was administered due to a concern for concurrent lidocaine toxicosis and to bind some of the previously administered antiarrhythmic medications, which may have increased the defibrillation threshold (DFT). Return of spontaneous circulation was achieved after 16 min of CPR. After being discharged, the dog was treated with mexiletine and sotalol long term and continued to do well 12 months later despite persistent VT.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> New or Unique Information Provided</h3>\u0000 \u0000 <p>This report describes a case of CPA secondary to intractable VT refractory to both injectable antiarrhythmic medication and attempted electrical cardioversion. Evidence suggests that antiarrhythmic medications can have positive or negative effects on the DFT, which may affect the success of electrical cardioversion or defibrillation. ILE was administered to bind the lipophilic antiarrhythmic medications due to concern that they were increasing the DFT. In patients with malignant arrhythmias, use of antiarrhythmic medication is often essential; however, clinicians should consider its potential impact on the DFT during subsequent cardioversion or defibrillation.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17603,"journal":{"name":"Journal of veterinary emergency and critical care","volume":"36 1","pages":"114-121"},"PeriodicalIF":1.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12950937/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146108980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retrospective Evaluation of a Standardized Image-Guided Nasogastric Tube Placement Protocol for Preventing Airway Placement in Dogs and Cats: 582 Cases","authors":"Rebecca C. Ewel,&nbsp;Nyssa A. Levy,&nbsp;Matthew W. Beal","doi":"10.1111/vec.13471","DOIUrl":"10.1111/vec.13471","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To evaluate the effectiveness of a standardized placement protocol in preventing inappropriate airway placement of nasogastric tubes (NGTs).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Design</h3>\u0000 \u0000 <p>Retrospective study.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Setting</h3>\u0000 \u0000 <p>University teaching hospital.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Animals</h3>\u0000 \u0000 <p>Five hundred eighty-two client-owned dogs and cats undergoing NGT placement between September 2021 and March 2023.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Medical records and digital radiographic records of all dogs and cats that were charged for NGT from September 1, 2021, to March 1, 2023, were reviewed. Data collected included patient species, breed, sedation protocol, proper or improper radiographic placement on thoracic inlet (TI) and last rib (LR) images, whether a stylet was used, and the number of attempts for successful placement in the stomach.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 582 NGT placement events were included, with 415 in dogs and 167 in cats. Airway positioning of the NGT was identified in the TI image in 57 events. Fifty-two of these were corrected immediately, and five were improperly advanced into the small airways due to operator misinterpretation of the TI image. Four small airway NGT misplacements were corrected and replaced prior to NGT use, with a total of 581 successful placement events. Median number of attempts for successful placement was 1 (range 1–9). Sedation was utilized in 515 of 582 placements and general anesthesia in 37 of 582. A stylet was used in 421 of 582 placement events. There was no association found between the use of sedation, anesthesia, or a stylet and airway positioning in the TI image.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The described protocol identified initial NGT placement into the trachea in 9.8% of cases. Prevention of inappropriate small airway placement requires both adherence to protocol and appropriate image interpretation.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17603,"journal":{"name":"Journal of veterinary emergency and critical care","volume":"36 1","pages":"56-60"},"PeriodicalIF":1.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12950928/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146108978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retrospective Evaluation of Treatment of Coagulopathy Secondary to Suspected Vitamin K Antagonist Rodenticide Intoxication With Cryosupernatant Transfusion in Seven Dogs (2000–2017)","authors":"Alyx L. Tracy,&nbsp;Christine A. Culler,&nbsp;Edward Cooper,&nbsp;Julien Guillaumin","doi":"10.1111/vec.70095","DOIUrl":"10.1111/vec.70095","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To report the use of cryosupernatant (CS) transfusion for the treatment of suspected vitamin K antagonist rodenticide (VKAR)-associated coagulopathy in dogs and its impact on coagulation times.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Design</h3>\u0000 \u0000 <p>Retrospective case series (2000–2017).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Setting</h3>\u0000 \u0000 <p>University teaching hospital.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Animals</h3>\u0000 \u0000 <p>Seven dogs with hemorrhage associated with suspected VKAR intoxication treated with CS transfusion.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Interventions</h3>\u0000 \u0000 <p>CS transfusion.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Measurements and Main Results</h3>\u0000 \u0000 <p>The median age was 3.0 years, with a median weight of 17.7 kg. Initial coagulation testing revealed median one-stage prothrombin time and activated partial thromboplastin time of 697% and 393%, respectively, above control/average of the reference range (CARR). The median dose of CS was 11.0 mL/kg. One-stage prothrombin time decreased (<i>p</i> = 0.043) after CS transfusion to a median of 98% of CARR. Activated partial thromboplastin time (<i>n</i> = 3) decreased to 114% of CARR (sample size precluded statistical analysis) upon recheck. All dogs received vitamin K supplementation, with an initial median subcutaneous dose of 4.11 mg/kg. Initial median PCV and total plasma protein concentration were 27.0% and 4.5 g/dL (45 g/L), respectively, with posttransfusion PCV and total plasma protein concentration of 22.0% and 4.9 g/dL, respectively. Six dogs showed resolution of observed clinical hemorrhage and were discharged. One dog was euthanized due to multi-organ dysfunction. No transfusion reactions were reported.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Dogs with suspected VKAR intoxication showed resolution of clinical hemorrhage after CS transfusion. Compared with fresh frozen plasma, CS is an option for treating VKAR-associated coagulopathy, despite lower factor IX activity.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17603,"journal":{"name":"Journal of veterinary emergency and critical care","volume":"36 1","pages":"84-88"},"PeriodicalIF":1.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146046955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}