Brittany D. Enders DVM, DACVECC, Sarah E. Musulin DVM, DACVECC, Marie K. Holowaychuk DVM, DACVECC, Anne S. Hale DVM
{"title":"Evaluation of the safety and effect of lyophilized canine-specific albumin to increase serum albumin concentration and colloid osmotic pressure in healthy dogs","authors":"Brittany D. Enders DVM, DACVECC, Sarah E. Musulin DVM, DACVECC, Marie K. Holowaychuk DVM, DACVECC, Anne S. Hale DVM","doi":"10.1111/vec.13432","DOIUrl":"10.1111/vec.13432","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To evaluate the safety of repeated administration of a lyophilized canine-specific albumin (CSA) product and to quantify its effect on serum albumin concentrations and colloid osmotic pressure (COP) in healthy dogs.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Design</h3>\u0000 \u0000 <p>Prospective study.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Setting</h3>\u0000 \u0000 <p>University research facility.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Animals</h3>\u0000 \u0000 <p>Six healthy, adult, purpose-bred Beagles.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Interventions</h3>\u0000 \u0000 <p>Dogs received 1 g/kg of 16% CSA intravenously on days 1, 2, and 14 and were observed, with serial measurement of vital parameters during and for 2 hours after each infusion, to monitor for adverse events or evidence of a hypersensitivity reaction. Serum albumin concentration and COP were measured at predetermined time points before and after each infusion.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>One dog experienced a single episode of vomiting approximately 1 hour after completion of the second infusion. No other adverse reactions were observed during the 28-day study period. Serum albumin concentration was increased by a mean of 0.57 g/dL (5.7 g/L) (<i>P </i>= 0.003) when measured 2 hours after the first CSA infusion, and albumin concentration remained significantly higher than baseline at 24 hours after infusion, with a mean difference of 0.42 g/dL (4.2 g/dL) (<i>P </i>< 0.001). The second and third CSA infusions similarly increased serum albumin concentration at 2 hours (<i>P </i>= 0.001 and <i>P </i>= 0.001, respectively) and 24 hours (<i>P </i>= 0.012 and <i>P </i>= 0.007, respectively) after infusion. COP increased by a mean of 2.03 mm Hg at 2 hours after the first infusion (<i>P </i>= 0.013) and remained significantly higher than baseline at 24 hours after infusion, with a mean difference of 1.52 mm Hg (<i>P </i>= 0.002). The second CSA infusion similarly increased COP at 2 hours (<i>P </i>< 0.001) and 24 hours (<i>P </i>= 0.017) after infusion. The third CSA infusion increased COP at 2 hours after infusion (<i>P </i>= 0.004) but did not achieve statistical significance at 24 hours after infusion (<i>P </i>= 0.053).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>A 1-g/kg dose of lyophilized CSA was effective at increasing serum albumin concentration and COP. Repeated infusions of CSA appear safe in healthy dogs.</p>\u0000 </section>\u0000 ","PeriodicalId":17603,"journal":{"name":"Journal of veterinary emergency and critical care","volume":"34 6","pages":"524-529"},"PeriodicalIF":1.1,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142669890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of intranasal atipamezole by atomization or drops with intramuscular injection for reversing sedative effects of medetomidine in healthy dogs","authors":"Majid Jafarbeglou DVM, DVSc, Mehdi Marjani DVM, DVSc, Mohammadreza Oghbaei DVM, Mohammadreza Paryani DVM, PhD, Reza Bakhshi-Khanghah DVM","doi":"10.1111/vec.13439","DOIUrl":"10.1111/vec.13439","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To determine and compare the efficacy of intranasal (IN) atomization, IN drops, and IM injection of atipamezole for reversal of medetomidine-induced sedation in healthy dogs.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Design</h3>\u0000 \u0000 <p>Prospective, randomized, blinded study.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Setting</h3>\u0000 \u0000 <p>University teaching hospital.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Animals</h3>\u0000 \u0000 <p>Forty mixed-breed, shelter-owned dogs with an average weight of 29.9 ± 5.6 kg (mean ± SD) that required sedation for minor diagnostic or therapeutic procedures.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Interventions</h3>\u0000 \u0000 <p>Atipamezole was administered by a dog handler at 200 µg/kg via IN atomization (ATI-IN<sub>A</sub>, <i>n</i> = 10), IN drops (ATI-IN<sub>D</sub>, <i>n</i> = 10), or IM injection (ATI-IM, <i>n</i> = 10) 20 minutes following medetomidine administration (40 µg/kg). A control group (<i>n</i> = 10) received no atipamezole.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Measurements and Main Results</h3>\u0000 \u0000 <p>Ease of atipamezole administration was evaluated. Sedation score, heart rate (HR), respiratory rate (RR), and blood pressure (BP) were recorded pre-medetomidine administration (T0), pre-atipamezole administration (T20), and at multiple intervals following atipamezole administration. ATI-IM resulted in the fastest recovery, followed by ATI-IN<sub>A</sub>, with ATI-IN<sub>D</sub> being the slowest. The adverse cardiovascular impacts of medetomidine were not completely mitigated. ATI-IM showed initial HR restoration followed by a decline. HR in both IN groups showed a slower increase compared to ATI-IM, but no subsequent decline was observed. ATI-IM resulted in a transient decrease in BP, though dogs remained normotensive. A gradual reduction in BP was noted in the IN groups. At T50, RR of all atipamezole groups differed from control, and a significant increase in RR was observed in ATI-IM dogs compared to pre-atipamezole value. No adverse effects were observed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>All routes for atipamezole administration effectively reversed medetomidine-induced sedation, with ATI-IM being fastest. IN routes were easy for the dog handler to administer, making them viable alternatives in cases of accidental drug exposure, particularly outside a hospital setting.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17603,"journal":{"name":"Journal of veterinary emergency and critical care","volume":"34 6","pages":"530-538"},"PeriodicalIF":1.1,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142669913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Samantha K. Day BVSc, MANZCVS, DACVECC, Katherine J. Nash BVSc, MS, MANZCVS, DACVECC, Mark J. Midwinter BMedSci, MB BS, MD, FRCS, CBE, Sarah L. Purcell BVSc, MANZCVS, MVECC, DACVECC, Wendy A. Goodwin PhD, BVSc, FANZCVS
{"title":"The establishment of reference intervals for the ClotPro thromboelastometry device in healthy dogs","authors":"Samantha K. Day BVSc, MANZCVS, DACVECC, Katherine J. Nash BVSc, MS, MANZCVS, DACVECC, Mark J. Midwinter BMedSci, MB BS, MD, FRCS, CBE, Sarah L. Purcell BVSc, MANZCVS, MVECC, DACVECC, Wendy A. Goodwin PhD, BVSc, FANZCVS","doi":"10.1111/vec.13426","DOIUrl":"10.1111/vec.13426","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To establish reference intervals using a new point-of-care thromboelastometry device in dogs for the extrinsically activated test (EX-test), intrinsically activated test (IN-test), fibrin polymerization test (FIB-test), ecarin test (ECA-test), and tissue plasminogen activator test (TPA-test) and to investigate the effects of storage time on the results.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Design</h3>\u0000 \u0000 <p>Prospective clinical study in 2022.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Setting</h3>\u0000 \u0000 <p>University teaching hospital.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Animals</h3>\u0000 \u0000 <p>Forty-eight healthy privately or university-owned dogs were prospectively enrolled and included on the basis of normal physical examination and normal baseline laboratory results (CBC, biochemistry profile, prothrombin time, and activated partial thromboplastin time [aPTT]).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Interventions</h3>\u0000 \u0000 <p>After a 30-minute storage time, the EX-test, IN-test, FIB-test, ECA-test, and TPA-test were performed on citrated blood samples. To determine the effect of storage time, 11 samples had the EX-test, FIB-test, and IN-test repeated 90 and 150 minutes after sample collection.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Measurements and Main Results</h3>\u0000 \u0000 <p>Ten thromboelastometry parameters were evaluated for each test. Reference intervals were calculated using the robust method for parametric data, and the robust Box–Cox transformed or nonparametric methods were used for nonparametric data. Increasing storage time resulted in more hypocoagulable tracings. A correlation was found between the IN-test and aPTT (<i>r</i> = 0.62, <i>P</i> < 0.0001). Other weak to moderate correlations were seen between thromboelastometry parameters and platelet count and hematocrit.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions and Clinical Importance</h3>\u0000 \u0000 <p>The development of reference intervals for the thromboelastometry device allows for the clinical use of this technology. Analyzing samples after a prolonged storage time of more than 30 minutes may result in erroneous results. Results may also be affected by an abnormal hematocrit or platelet count.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17603,"journal":{"name":"Journal of veterinary emergency and critical care","volume":"34 6","pages":"560-569"},"PeriodicalIF":1.1,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/vec.13426","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142649849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Santarelli DVM, PhD, DECVIM, P. Sebastián Marcos DVM, MSc, DECVIM, J. Talavera DVM, PhD, S. D. Aznar-Cervantes PhD, J. Fernández del Palacio DVM, PhD, DECVIM
{"title":"Evaluation of a rapid test for point-of-care detection of cardiac troponin I in serum of healthy and diseased dogs and cats","authors":"G. Santarelli DVM, PhD, DECVIM, P. Sebastián Marcos DVM, MSc, DECVIM, J. Talavera DVM, PhD, S. D. Aznar-Cervantes PhD, J. Fernández del Palacio DVM, PhD, DECVIM","doi":"10.1111/vec.13438","DOIUrl":"10.1111/vec.13438","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>(1) To compare the results of a rapid test for qualitative detection of cardiac troponin I (cTnI) values >1 ng/mL with those obtained using a reference quantitative method and (2) to perform a semiquantitative assessment of rapid test results using this point-of-care (POC) assay.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Design</h3>\u0000 \u0000 <p>Prospective cross-sectional study from April 2015 to November 2020.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Setting</h3>\u0000 \u0000 <p>Secondary referral hospital.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Animals</h3>\u0000 \u0000 <p>Eighty dogs and 20 cats, with and without cardiovascular disease.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Interventions</h3>\u0000 \u0000 <p>None.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Measurements and Main Results</h3>\u0000 \u0000 <p>Serum samples were obtained, and cTnI rapid test was conducted in parallel with chemiluminescence assay (reference standard). Positive results from the rapid test were further classified as mild and strong positives, based on subjective assessment of the color intensity of the test line. Rapid test was deemed valid in all patients. There was agreement for positive samples between the qualitative and quantitative techniques in 31 dogs and 5 cats, and for negative samples in 43 dogs and 13 cats, resulting in a strong and moderate agreement, respectively. There was a significant difference between color scale groups.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The rapid test assessed provides a feasible POC option to determine concentrations of cTnI >1 ng/mL in dogs and cats and shows a moderate to strong agreement with a validated conventional quantitative assay. Furthermore, semiquantitative assessment allows estimation of the magnitude of the elevation.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17603,"journal":{"name":"Journal of veterinary emergency and critical care","volume":"34 6","pages":"539-544"},"PeriodicalIF":1.1,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142669915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Charles T. Talbot BVSc, PGDip(VCP), DACVECC, Marc R. Raffe DVM, MS, DAVCAA, DACVECC, Manuel Boller Dr med vet, MTR, DACVECC, Melissa L. Edwards DVM, DACVECC, Kelly E. Hall DVM, MS, DACVECC
{"title":"ACVECC-Veterinary Committee on Trauma registry report 2020–2021","authors":"Charles T. Talbot BVSc, PGDip(VCP), DACVECC, Marc R. Raffe DVM, MS, DAVCAA, DACVECC, Manuel Boller Dr med vet, MTR, DACVECC, Melissa L. Edwards DVM, DACVECC, Kelly E. Hall DVM, MS, DACVECC","doi":"10.1111/vec.13436","DOIUrl":"10.1111/vec.13436","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To report summative data from the American College of Veterinary Emergency and Critical Care (ACVECC)-Veterinary Committee on Trauma (VetCOT) registry, with further individual evaluation of university and private practices and level I and II Veterinary Trauma Centers (VTCs).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Design</h3>\u0000 \u0000 <p>Multi-institutional registry data report, January 1, 2020, to December 31, 2021.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Setting</h3>\u0000 \u0000 <p>VTCs identified and verified by ACVECC-VetCOT.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Animals</h3>\u0000 \u0000 <p>Dogs and cats with evidence of trauma.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Interventions</h3>\u0000 \u0000 <p>Data were input to a web-based data capture system (REDCap) by data entry personnel trained in registry software use and operational definitions of data variables. Patient data on demographics, trauma type, preadmission care, trauma severity assessment at presentation (modified Glasgow Coma Score and Animal Trauma Triage score), key laboratory parameters, interventions, and outcome were collected. Summary descriptive data for each species are reported.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Measurements and Main Results</h3>\u0000 \u0000 <p>Twenty-two VTCs contributed data to the VetCOT registry during a 24-month period, culminating in a total of 9758 complete trauma case records for dogs and 11734 for cats. Head trauma in dogs and cats was seen at a higher percentage in both university-only VTCs (encompassing both level I and II) (20.1% and 24.1%, respectively) and level I-only VTCs (24.3% and 24.1%, respectively), in comparison to private-only VTCs (encompassing both level I and II) (13.5% and 16.2%, respectively) and individual level II VTCs (14.1% and 18.9%, respectively). Canine and feline surgical procedures were performed at a higher percentage at university VTCs (50% and 40.5%, respectively) compared to private VTCs (39.2% and 28.6%, respectively). Overall survival to discharge for dogs and cats remains high at 93.1% and 83.6%, respectively.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The VetCOT registry has continued to show powerful potential in collating a large, multifaceted, international dataset in trauma for both dogs and cats. As published in previous VetCOT registry reports, survival to di","PeriodicalId":17603,"journal":{"name":"Journal of veterinary emergency and critical care","volume":"34 6","pages":"517-523"},"PeriodicalIF":1.1,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/vec.13436","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142570535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clara Mattavelli DVM, Matthew Simpson BVMS, Balazs Szladovits DVM, DACVP, Laura de los Santos DVM, Richard Meeson MA, VetMB, PhD, MVetMed, DECVS, Sarah Tayler BVetMed (Hons), MVetMed, DACVIM, DECVIM, Laura Cole MA, VetMB, MVetMed, DACVECC, DECVECC
{"title":"Bicavitary septic effusion associated with staphylococcal cholecystitis in a dog","authors":"Clara Mattavelli DVM, Matthew Simpson BVMS, Balazs Szladovits DVM, DACVP, Laura de los Santos DVM, Richard Meeson MA, VetMB, PhD, MVetMed, DECVS, Sarah Tayler BVetMed (Hons), MVetMed, DACVIM, DECVIM, Laura Cole MA, VetMB, MVetMed, DACVECC, DECVECC","doi":"10.1111/vec.13434","DOIUrl":"10.1111/vec.13434","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To describe a case of concurrent septic pyothorax, peritonitis, and cholecystitis due to <i>Staphylococcus pseudintermedius</i> in a dog.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Summary</h3>\u0000 \u0000 <p>A 10-year-old neutered male, medium-sized, mixed-breed dog presented with an acute abdomen. Initial investigations found the presence of a septic pyothorax, septic peritonitis, and bacterial cholecystitis. Exploratory celiotomy did not identify the source of infection, and no macroscopic communication between pleural and peritoneal space was detected. An abdominal Jackson-Pratt drain and bilateral small-bore thoracostomy tubes were placed for further management, with the dog receiving antimicrobial therapy and intensive supportive care. Subsequently, microbiological cultures confirmed scant growth of <i>S. pseudintermedius</i> in bile, pleural, and peritoneal fluid. The dog was discharged after 1 week of hospitalization. Antimicrobial therapy was discontinued 4 weeks after discharge due to an improvement of clinical signs and normalization of C-reactive protein concentration. A diagnosis of hyperadrenocorticism was made 6 weeks after discharge, and appropriate therapy was initiated.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> New or Unique Information Provided</h3>\u0000 \u0000 <p>Septic peritonitis and septic pyothorax are both common life-threatening conditions in veterinary medicine. To the authors’ knowledge, this is the first report describing septic bicavitary effusion associated with a biliary staphylococcal infection in a dog. The exact mechanism by which the infection spread remains unclear, but hematogenous or lymphatic routes are considered the most probable. However, the presence of microscopic diaphragmatic defects and an anicteric gallbladder rupture cannot completely be excluded. The concurrent hyperadrenocorticism may have also contributed to an immunocompromised state, predisposing the dog to the development of infection.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17603,"journal":{"name":"Journal of veterinary emergency and critical care","volume":"34 6","pages":"585-591"},"PeriodicalIF":1.1,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142570537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pablo A. Donati DVM, MS, Lisa Tarragona DVM, MS, PhD, Andrea S. Zaccagnini DVM, Nestor M. Nigro DVM, Alfredo J. Díaz DVM, Santiago E. Fuensalida DVM, Ignacio Sández Cordero DVM, Ignacio M Espiñeira I DVM, Pablo E Otero PhD
{"title":"Evaluation of cerebral autoregulation in dogs via transcranial color-coded duplex sonography and transient hyperemia testing","authors":"Pablo A. Donati DVM, MS, Lisa Tarragona DVM, MS, PhD, Andrea S. Zaccagnini DVM, Nestor M. Nigro DVM, Alfredo J. Díaz DVM, Santiago E. Fuensalida DVM, Ignacio Sández Cordero DVM, Ignacio M Espiñeira I DVM, Pablo E Otero PhD","doi":"10.1111/vec.13430","DOIUrl":"10.1111/vec.13430","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To evaluate the changes in flow velocities of the middle cerebral artery before and after a carotid compression maneuver using transcranial color-coded duplex sonography (TCCD) in healthy anesthetized dogs under mechanical ventilation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Design</h3>\u0000 \u0000 <p>Prospective study.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Setting</h3>\u0000 \u0000 <p>University teaching hospital.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Animals</h3>\u0000 \u0000 <p>Eleven healthy adult dogs.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Interventions</h3>\u0000 \u0000 <p>A 5-second carotid occlusion maneuver was performed to evaluate cerebral autoregulation (CA).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Measurements and Main Results</h3>\u0000 \u0000 <p>After 10 minutes of stable anesthesia, the middle cerebral artery was evaluated by TCCD. Dogs were positioned in sternal recumbency with the head raised to the level of the phlebostatic axis. The systolic peak velocity (Vp) was measured using pulsed Doppler mode. CA was evaluated through the transient hyperemia test (THT), which assesses changes in the Vp after a 5-second transient compression of the ipsilateral common carotid artery and is expressed as the ratio between the Vp flow before and after carotid compression. The Vp before and after carotid occlusion was compared using the Wilcoxon signed-rank test. The median Vp of the middle cerebral artery after the carotid compression maneuver was significantly higher than the median Vp before compression (median [interquartile range, IQR]: 47.7 cm/s [34.3] vs 64.1 cm/s [24.4]; <i>P</i> = 0.003). The median THT obtained was 1.20 (IQR: 0.37).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The current study demonstrated a significant increase in the Vp of the middle cerebral artery after a 5-second temporary occlusion of the ipsilateral carotid artery in healthy anesthetized dogs under mechanical ventilation. These findings suggest that the noninvasive TCCD methodology could be valuable for assessing CA in dogs. Additional studies using this technique in neurocritical animals are required to confirm its usefulness.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17603,"journal":{"name":"Journal of veterinary emergency and critical care","volume":"34 6","pages":"554-559"},"PeriodicalIF":1.1,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142570540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrew D. Lukasiewicz DVM, Katie D. Mauro DVM, DACVECC, Tara D. Assenmacher DVM, DACVECC
{"title":"Pancreatic torsion in a puppy with an acute abdomen","authors":"Andrew D. Lukasiewicz DVM, Katie D. Mauro DVM, DACVECC, Tara D. Assenmacher DVM, DACVECC","doi":"10.1111/vec.13433","DOIUrl":"10.1111/vec.13433","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To describe the treatment of a unique cause of acute abdomen in a puppy.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Summary</h3>\u0000 \u0000 <p>An 11-week, 5-day-old female intact Alaskan Malamute was presented to an emergency service for an acute onset of vomiting. On evaluation, the puppy was found to have cranial abdominal pain with an otherwise normal physical examination. An inflammatory leukogram with no other clinically significant findings was found on the initial diagnostics. An abdominal ultrasound showed peritoneal effusion and a lobulated structure in the left cranial abdomen. An emergency exploratory celiotomy was performed, during which evidence of torsion was found in the left limb of the pancreas, which was subsequently excised from the abdomen. The puppy was hospitalized overnight and discharged the next day. Histopathology of the pancreas was consistent with torsion.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Unique Information Provided</h3>\u0000 \u0000 <p>Pancreatic torsion is a rare but potential cause of acute abdomen in dogs and can be successfully treated with surgical excision.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17603,"journal":{"name":"Journal of veterinary emergency and critical care","volume":"34 6","pages":"579-584"},"PeriodicalIF":1.1,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/vec.13433","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142570541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Jennifer J. Devey","authors":"Elke Rudloff, Alyce D'Amato, Ira Zaslow","doi":"10.1111/vec.13409","DOIUrl":"10.1111/vec.13409","url":null,"abstract":"","PeriodicalId":17603,"journal":{"name":"Journal of veterinary emergency and critical care","volume":"34 5","pages":"509"},"PeriodicalIF":1.1,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142402234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fabio Viganó","authors":"","doi":"10.1111/vec.13419","DOIUrl":"10.1111/vec.13419","url":null,"abstract":"","PeriodicalId":17603,"journal":{"name":"Journal of veterinary emergency and critical care","volume":"34 5","pages":"510"},"PeriodicalIF":1.1,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142402233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}