Morgan Alexandra Stark, Paula M. Simons, Bridget Mary Lyons
{"title":"中性粒细胞与淋巴细胞比值作为犬细菌性肺炎诊断指标的评价。","authors":"Morgan Alexandra Stark, Paula M. Simons, Bridget Mary Lyons","doi":"10.1111/vec.13475","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Objective</h3>\n \n <p>To determine the ability of the blood neutrophil-to-lymphocyte ratio (NLR) to differentiate between bacterial pneumonia and nonbacterial pneumonia in dogs undergoing airway sampling.</p>\n </section>\n \n <section>\n \n <h3> Design</h3>\n \n <p>Retrospective study.</p>\n </section>\n \n <section>\n \n <h3> Setting</h3>\n \n <p>A university teaching hospital and affiliated private practice specialty hospital.</p>\n </section>\n \n <section>\n \n <h3> Animals</h3>\n \n <p>Forty-one client-owned dogs undergoing airway sampling with CBCs performed within 48 h of collecting airway lavage samples between January 2018 and December 2022.</p>\n </section>\n \n <section>\n \n <h3> Interventions</h3>\n \n <p>None.</p>\n </section>\n \n <section>\n \n <h3> Measurements and Main Results</h3>\n \n <p>Medical records were reviewed and the following parameters were recorded: signalment, length of hospitalization, WBC count, neutrophil count, lymphocyte count, type of airway sampling, airway cytology and culture results, timing of antimicrobial use, radiographic findings, concurrent diseases, final diagnosis, and outcome. Patients that received corticosteroids or had hematological neoplasia were excluded. Of the 41 dogs included, 51.2% (21/41) were diagnosed with bacterial pneumonia. Twenty-three patients (56.1%) received antimicrobials before airway lavage, and 11 (47.8%) of these dogs were diagnosed with bacterial pneumonia. Of the 18 patients (43.9%) that did not receive antimicrobials before airway lavage, 10 (55.6%) were diagnosed with bacterial pneumonia. One dog (2.4%) underwent a transtracheal wash, 16 (39%) underwent a bronchoalveolar lavage, and 24 (58.5%) underwent an endotracheal wash. NLR was not significantly associated with bacterial pneumonia (<i>p</i> = 0.248). In dogs with bacterial pneumonia, NLR was not associated with mortality (<i>p</i> = 0.454) or length of hospital stay (LOS) (<i>p</i> = 0.282). NLR was positively associated with LOS when all dogs were analyzed together (<i>p</i> = 0.042).</p>\n </section>\n \n <section>\n \n <h3> Conclusions</h3>\n \n <p>NLR was not different in dogs with bacterial pneumonia than in dogs without bacterial pneumonia. NLR was positively associated with LOS when all dogs were included in the analysis (<i>p</i> = 0.042).</p>\n </section>\n </div>","PeriodicalId":17603,"journal":{"name":"Journal of veterinary emergency and critical care","volume":"35 3","pages":"269-273"},"PeriodicalIF":1.2000,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Evaluation of Neutrophil-to-Lymphocyte Ratio as a Diagnostic Marker in Dogs With Bacterial Pneumonia\",\"authors\":\"Morgan Alexandra Stark, Paula M. Simons, Bridget Mary Lyons\",\"doi\":\"10.1111/vec.13475\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Objective</h3>\\n \\n <p>To determine the ability of the blood neutrophil-to-lymphocyte ratio (NLR) to differentiate between bacterial pneumonia and nonbacterial pneumonia in dogs undergoing airway sampling.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Design</h3>\\n \\n <p>Retrospective study.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Setting</h3>\\n \\n <p>A university teaching hospital and affiliated private practice specialty hospital.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Animals</h3>\\n \\n <p>Forty-one client-owned dogs undergoing airway sampling with CBCs performed within 48 h of collecting airway lavage samples between January 2018 and December 2022.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Interventions</h3>\\n \\n <p>None.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Measurements and Main Results</h3>\\n \\n <p>Medical records were reviewed and the following parameters were recorded: signalment, length of hospitalization, WBC count, neutrophil count, lymphocyte count, type of airway sampling, airway cytology and culture results, timing of antimicrobial use, radiographic findings, concurrent diseases, final diagnosis, and outcome. Patients that received corticosteroids or had hematological neoplasia were excluded. Of the 41 dogs included, 51.2% (21/41) were diagnosed with bacterial pneumonia. Twenty-three patients (56.1%) received antimicrobials before airway lavage, and 11 (47.8%) of these dogs were diagnosed with bacterial pneumonia. Of the 18 patients (43.9%) that did not receive antimicrobials before airway lavage, 10 (55.6%) were diagnosed with bacterial pneumonia. One dog (2.4%) underwent a transtracheal wash, 16 (39%) underwent a bronchoalveolar lavage, and 24 (58.5%) underwent an endotracheal wash. NLR was not significantly associated with bacterial pneumonia (<i>p</i> = 0.248). In dogs with bacterial pneumonia, NLR was not associated with mortality (<i>p</i> = 0.454) or length of hospital stay (LOS) (<i>p</i> = 0.282). NLR was positively associated with LOS when all dogs were analyzed together (<i>p</i> = 0.042).</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusions</h3>\\n \\n <p>NLR was not different in dogs with bacterial pneumonia than in dogs without bacterial pneumonia. 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Evaluation of Neutrophil-to-Lymphocyte Ratio as a Diagnostic Marker in Dogs With Bacterial Pneumonia
Objective
To determine the ability of the blood neutrophil-to-lymphocyte ratio (NLR) to differentiate between bacterial pneumonia and nonbacterial pneumonia in dogs undergoing airway sampling.
Design
Retrospective study.
Setting
A university teaching hospital and affiliated private practice specialty hospital.
Animals
Forty-one client-owned dogs undergoing airway sampling with CBCs performed within 48 h of collecting airway lavage samples between January 2018 and December 2022.
Interventions
None.
Measurements and Main Results
Medical records were reviewed and the following parameters were recorded: signalment, length of hospitalization, WBC count, neutrophil count, lymphocyte count, type of airway sampling, airway cytology and culture results, timing of antimicrobial use, radiographic findings, concurrent diseases, final diagnosis, and outcome. Patients that received corticosteroids or had hematological neoplasia were excluded. Of the 41 dogs included, 51.2% (21/41) were diagnosed with bacterial pneumonia. Twenty-three patients (56.1%) received antimicrobials before airway lavage, and 11 (47.8%) of these dogs were diagnosed with bacterial pneumonia. Of the 18 patients (43.9%) that did not receive antimicrobials before airway lavage, 10 (55.6%) were diagnosed with bacterial pneumonia. One dog (2.4%) underwent a transtracheal wash, 16 (39%) underwent a bronchoalveolar lavage, and 24 (58.5%) underwent an endotracheal wash. NLR was not significantly associated with bacterial pneumonia (p = 0.248). In dogs with bacterial pneumonia, NLR was not associated with mortality (p = 0.454) or length of hospital stay (LOS) (p = 0.282). NLR was positively associated with LOS when all dogs were analyzed together (p = 0.042).
Conclusions
NLR was not different in dogs with bacterial pneumonia than in dogs without bacterial pneumonia. NLR was positively associated with LOS when all dogs were included in the analysis (p = 0.042).
期刊介绍：
The Journal of Veterinary Emergency and Critical Care’s primary aim is to advance the international clinical standard of care for emergency/critical care patients of all species. The journal’s content is relevant to specialist and non-specialist veterinarians practicing emergency/critical care medicine. The journal achieves it aims by publishing descriptions of unique presentation or management; retrospective and prospective evaluations of prognosis, novel diagnosis, or therapy; translational basic science studies with clinical relevance; in depth reviews of pertinent topics; topical news and letters; and regular themed issues.
The journal is the official publication of the Veterinary Emergency and Critical Care Society, the American College of Veterinary Emergency and Critical Care, the European Veterinary Emergency and Critical Care Society, and the European College of Veterinary Emergency and Critical Care. It is a bimonthly publication with international impact and adheres to currently accepted ethical standards.
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