Journal of wound care最新文献_第3页

Pressure injuries in patients receiving extracorporeal membrane oxygenation: a tertiary centre experience. 压力损伤患者接受体外膜氧合：三级中心经验。

IF 1.7 4区医学

Journal of wound care Pub Date : 2025-08-02 DOI: 10.12968/jowc.2023.0218

Halide Oğuş, A Ece Altınay, Fatih Yiğit, Ayhan Güneş, Yeliz Karacı, Seda Karasakal, Merve Karanis Taştan, Ceyda Canbey Baydilli, Şirin Menekşe, Mehmet Kaan Kırali

{"title":"Pressure injuries in patients receiving extracorporeal membrane oxygenation: a tertiary centre experience.","authors":"Halide Oğuş, A Ece Altınay, Fatih Yiğit, Ayhan Güneş, Yeliz Karacı, Seda Karasakal, Merve Karanis Taştan, Ceyda Canbey Baydilli, Şirin Menekşe, Mehmet Kaan Kırali","doi":"10.12968/jowc.2023.0218","DOIUrl":"10.12968/jowc.2023.0218","url":null,"abstract":"Objective: Pressure injuries (PIs) are common in patients receiving intensive care and extracorporeal membrane oxygenation (ECMO). This study assessed the incidence and risk factors of PIs in patients receiving ECMO for COVID-19-associated acute respiratory distress syndrome (ARDS).Method: Patients who were admitted to the intensive care unit (ICU) with severe COVID-19-associated ARDS and received veno-venous ECMO between April 2020 and January 2022 were evaluated. All patients were monitored, evaluated and managed according to the Prevention and treatment of pressure ulcers: clinical practice guideline 2019. The risk for PI was evaluated using the Braden scale. Staging of PIs was made according to the National Pressure Injury Advisory Panel guidelines.Results: A total of 78 patients (median age 45 years) received ICU care and ECMO support. Of these, 75 patients were transferred to the ICU while on ECMO support; 24/78 (30.8%) patients already had PIs. New PIs developed in 24 patients (24/54, 44.4%) during prolonged periods of ECMO (median 48.5 days). The new PIs were mainly stage 2 (55%). The median time to new PI development during ECMO was 21 (range 4-60) days. The mortality rate was 32/54 (59.3%). In multivariable analysis, age (odds ratio (OR): 1.103, 95% confidence interval (CI): 1.022, 1.191; p=0.027) and ECMO duration (OR: 1.048, 95% CI: 1.016, 1.081; p=0.003) were independent predictors of PI development.Conclusion: Strict compliance with the clinical practice guidelines for PIs by a dedicated ICU team may considerably reduce the incidence of PIs among patients receiving ECMO for prolonged periods.","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 8","pages":"571-578"},"PeriodicalIF":1.7,"publicationDate":"2025-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144835504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Empowering tomorrow's innovators: the significance of student-led research. 赋能未来的创新者：学生主导研究的重要性。

IF 1.7 4区医学

Journal of wound care Pub Date : 2025-08-02 DOI: 10.12968/jowc.2025.0305

Windy Cole

引用次数: 0

Effects of single-use negative pressure wound therapy on healthcare use: US analysis of a large claims database. 一次性负压伤口治疗对医疗保健使用的影响：美国对大型索赔数据库的分析。

IF 1.7 4区医学

Journal of wound care Pub Date : 2025-08-02 Epub Date: 2025-07-28 DOI: 10.12968/jowc.2024.0339

Ravi K Bashyal, Richard Searle, Leo M Nherera, Adam Wright

{"title":"Effects of single-use negative pressure wound therapy on healthcare use: US analysis of a large claims database.","authors":"Ravi K Bashyal, Richard Searle, Leo M Nherera, Adam Wright","doi":"10.12968/jowc.2024.0339","DOIUrl":"10.12968/jowc.2024.0339","url":null,"abstract":"Objective: To assess the effect of two single-use negative pressure wound therapy (sNPWT) devices on healthcare resource use (HCRU) and surgical site complications (SSCs) after orthopaedic and cardiovascular surgery.Method: Patient data were collected from the US-based Premier PINC AI Healthcare Database between January 2017 and June 2022. Adult patients upon whom the -80mmHg or -125mmHg sNPWT device was used within predefined orthopaedic and cardiovascular surgical categories were included. The HCRU endpoints measured were index encounter length of stay (LoS), and cost at index encounter and at 30 and 90 days post-surgery. Clinical endpoints were also assessed.Results: The mean index encounter LoS, and mean cost at index admission and at 30 and 90 days post-surgery were all significantly lower when the -80mmHg device was used, compared with the -125mmHg device, across orthopaedic and cardiovascular wounds (all p<0.0001). The odds ratio (OR) for dehiscence (30 days) was significantly lower when the -80mmHg device was used versus the -125mmHg device in orthopaedic (OR: 0.361; p≤0.05) and cardiovascular (OR: 0.422; p≤0.01) wounds. Differences between the devices were not found in superficial and deep surgical site infections or seroma for either orthopaedic or cardiovascular incisions (p>0.05).Conclusion: The -80mmHg device was associated with significantly lower HCRU and likelihood of dehiscence after orthopaedic and cardiovascular surgery versus the -125mmHg device and there were no differences in other SSCs.","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 8","pages":"555-562"},"PeriodicalIF":1.7,"publicationDate":"2025-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144835501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acute microcirculatory effects of remote ischaemic conditioning in hard-to-heal wounds. 远端缺血条件对难愈合伤口急性微循环的影响。

IF 1.7 4区医学

Journal of wound care Pub Date : 2025-08-02 DOI: 10.12968/jowc.2023.0134

Julia Lucius, Mascha Groß, Sophie Schleusser, Henriette Deichmann, Marco Horn, Raphael R Tasar, Jan-Oluf Jensen, Felix H Stang, Peter Mailänder, Tobias Kisch

{"title":"Acute microcirculatory effects of remote ischaemic conditioning in hard-to-heal wounds.","authors":"Julia Lucius, Mascha Groß, Sophie Schleusser, Henriette Deichmann, Marco Horn, Raphael R Tasar, Jan-Oluf Jensen, Felix H Stang, Peter Mailänder, Tobias Kisch","doi":"10.12968/jowc.2023.0134","DOIUrl":"10.12968/jowc.2023.0134","url":null,"abstract":"Objective: Remote ischaemic conditioning (RIC) is known to have a positive impact on heart muscle cells, kidney and liver cells. RIC improves microcirculation in healthy skin. Microcirculation is a crucial factor in wound healing. This study examined the microcirculatory effects of RIC in hard-to-heal (chronic) wounds based on the hypothesis that RIC improves cutaneous microcirculation in hard-to-heal wounds.Method: Patients with hard-to-heal wounds (>3 weeks) participated in the study. RIC comprised three ischaemia cycles (five-minute inflation of blood pressure cuff to 200mmHg), each followed by a 10-minute reperfusion phase on a healthy upper limb. After the third and final ischaemia cycle, a reperfusion of 20 minutes ensued. Microcirculation was continuously recorded through a combined laser Doppler and white light spectrometry.Results: The cohort comprised 20 patients. In hard-to-heal wounds, oxygen saturation in a 6-8mm tissue depth was increased by a maximum of 11.2% (percentage change from baseline; p<0.02) and capillary blood flow was increased by a maximum of 47.7% (p<0.0001). There was no significant change of the postcapillary venous filling pressure.Conclusion: The results of this study showed that RIC enhanced microcirculation in hard-to-heal wounds by elevating capillary blood flow and oxygen saturation.","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 8","pages":"631-636"},"PeriodicalIF":1.7,"publicationDate":"2025-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144835487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment of chronic wounds with cold plasma: a randomised, single-blind, placebo-controlled clinical study. 低温等离子体治疗慢性伤口：一项随机、单盲、安慰剂对照临床研究。

IF 1.7 4区医学

Journal of wound care Pub Date : 2025-08-02 Epub Date: 2025-07-28 DOI: 10.12968/jowc.2025.0207

Robert Strohal, Martina Mittlböck, Lisa Gebhardt, Gilbert Hämmerle

引用次数: 0

Rationale and technique for subulcer ultrasonic treatment of hard-to-heal diabetic foot ulcers. 难以愈合的糖尿病足溃疡的超声治疗的原理和技术。

IF 1.7 4区医学

Journal of wound care Pub Date : 2025-08-02 DOI: 10.12968/jowc.2022.0139

Lewis H Freed, Christopher G Parkin, Bernard F Morrey

引用次数: 0

Comparative effectiveness study of a bilayer cellular construct and dehydrated human amnion/chorion membrane in the treatment of pressure injuries. 双层细胞结构与脱水人羊膜/绒毛膜治疗压迫性损伤的疗效比较研究。

IF 1.7 4区医学

Journal of wound care Pub Date : 2025-08-02 DOI: 10.12968/jowc.2024.0070

Oscar M Alvarez, Tad Archambault, Michael L Sabolinski

{"title":"Comparative effectiveness study of a bilayer cellular construct and dehydrated human amnion/chorion membrane in the treatment of pressure injuries.","authors":"Oscar M Alvarez, Tad Archambault, Michael L Sabolinski","doi":"10.12968/jowc.2024.0070","DOIUrl":"10.12968/jowc.2024.0070","url":null,"abstract":"Objective: Using real-world data, a comparative effectiveness analysis of a bilayer living cellular construct (BLCC) versus a dehydrated human amnion/chorion membrane (dHACM) for use in the treatment of pressure injuries (PIs) was conducted.Method: Real-world data (RWD) in the form of electronic medical records of patients were analysed retrospectively. Patients with no baseline wound measurements or follow-up visits were excluded. Cox and Kaplan-Meier analyses were used to compute percentages and median times to healing, respectively.Results: A total of 1764 PIs were analysed and evaluations performed on 1046 BLCC- and 718 dHACM-treated wounds. The Cox hazard ratio (HR) demonstrated the probability of healing over 36 weeks. Patient populations were comparable. The median time to healing was 19.0 weeks for dHACM and 14.7 weeks for BLCC (i.e., 22.6% reduction in time for BLCC); p<0.0001. The frequency of healing for BLCC versus dHACM was significantly greater at week 8 (29% versus 21%, respectively); at week 12 (42% versus 32%, respectively); at week 24 (64% versus 52%, respectively), and at week 36 (73% versus 62%, respectively); p<0.0001. The HR=1.37 (95% confidence interval: 1.21, 1.56); p<0.0001. BLCC-treated PUs had a 37% greater probability of healing compared to dHACM throughout the study.Conclusion: In this study, findings showed that BLCC improved time, percentage of healed wounds and probability of healing PIs. RWD/comparative effectiveness analysis studies are beneficial to clinicians and help guide policymakers regarding reimbursement decisions.","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 8","pages":"616-622"},"PeriodicalIF":1.7,"publicationDate":"2025-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144835488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness of periwound regional oxygen saturation as a wound healing predictor of toes in patients with chronic limb-threatening ischaemia. 伤口周围区域血氧饱和度作为慢性肢体缺血性患者伤口愈合预测指标的有效性。

IF 1.7 4区医学

Journal of wound care Pub Date : 2025-08-02 DOI: 10.12968/jowc.2023.0042

Yu Kagaya, Norihiko Ohura, Yuki Morishige, Yuki Take-E, Mine Ozaki

{"title":"Effectiveness of periwound regional oxygen saturation as a wound healing predictor of toes in patients with chronic limb-threatening ischaemia.","authors":"Yu Kagaya, Norihiko Ohura, Yuki Morishige, Yuki Take-E, Mine Ozaki","doi":"10.12968/jowc.2023.0042","DOIUrl":"10.12968/jowc.2023.0042","url":null,"abstract":"Objective: To verify the utility and accuracy of periwound regional oxygen saturation (rSO2) as a wound healing predictor of toes in patients with chronic limb-threatening ischaemia (CLTI), and compare the results with skin perfusion pressure (SPP) measurements.Method: Patients with hard-to-heal (chronic) toe wounds and CLTI, and who had undergone toe rSO2 (near wound), forefoot rSO2 and SPP measurements, were retrospectively selected. Following the measurements, the patients were treated conservatively, and the progress of wound healing was evaluated 28-91 days after the rSO2/SPP measurements. Toe wounds were classified into two groups: healing and non-healing. Receiver operating characteristic curves were created for rSO2/SPP to evaluate the accuracy of the wound healing prediction index, and the area under the curve (AUC) was also evaluated.Results: A total of 118 toes from 76 limbs were included in the evaluation and analysis. The AUC of periwound rSO2 was 0.938 (cut-off value: 44%; sensitivity: 0.955; specificity: 0.793). The AUC of plantar forefoot rSO2 and SPP were 0.789 and 0.786, respectively. The dorsal forefoot rSO2 and SPP demonstrated lower accuracy as wound healing predictors compared with the plantar side (AUC: 0.551 and 0.758, respectively).Conclusion: In this retrospective study, periwound rSO2 was a highly accurate predictor of toe wound healing in patients with CLTI. Both plantar forefoot rSO2 and SPP demonstrated moderate-to-high accuracy as predictors of toe wound healing, but less than that for periwound rSO2. Prospective studies in controlled populations are required. New devices that can measure periwound perfusion may provide more accurate wound healing predictions.","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 8","pages":"580-588"},"PeriodicalIF":1.7,"publicationDate":"2025-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144835489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A closed-loop audit to assess and improve surgical site infection rates across all surgical specialties. 一个闭环审计，以评估和改善所有外科专业的手术部位感染率。

IF 1.7 4区医学

Journal of wound care Pub Date : 2025-08-02 DOI: 10.12968/jowc.2024.0185

Alvin Gardner, Emma Wates, Martin Kawabata, Kavita Sanghera, Basmal Ria, Roland Fernandes

{"title":"A closed-loop audit to assess and improve surgical site infection rates across all surgical specialties.","authors":"Alvin Gardner, Emma Wates, Martin Kawabata, Kavita Sanghera, Basmal Ria, Roland Fernandes","doi":"10.12968/jowc.2024.0185","DOIUrl":"10.12968/jowc.2024.0185","url":null,"abstract":"Objective: To assess surgical specialty performance against established national data and to assess the impact of a seven-point surgical site infection (SSI) reduction checklist on elective general surgery SSI rates; specifically, SSI rates of <1% following clean procedures and <10% following clean-contaminated surgery.Method: Retrospective data were collected on selected patients undergoing surgery between July-August 2022. Patient demographics, comorbidities, procedure, indication, SSI management, presence of additional complication and type of SSI were recorded. Follow-up telephone calls (with patient consent) were made to capture any additional SSIs. The reaudit period analysed elective general surgical procedures between May-June 2023, with the same data parameters. A perioperative seven-point checklist was implemented during the reaudit period in elective surgical theatres.Results: Overall, 955 patients were included in the retrospective review of data. Of these, 138 patients had developed a SSI, yielding a 14.5% SSI rate, and 249 patients were included in general surgery with 45 (18.1%) developing SSIs. A total of 38 additional SSIs were identified after telephone follow-up across all specialties, representing 3.97% of the total number of patients and 22.46% of total SSIs. The completion rate of the seven-point checklist during the reaudit period was 47% (n=100). The SSI rate was 1%, with the one reported case not having a completed checklist.Conclusion: The results of this audit showed there was scope for improvement to reduce SSIs across specialties. A significant proportion of SSIs required admission to hospital and were only identified after telephone follow-up. The seven-point SSI reduction checklist significantly reduced the SSI rate for elective general surgical procedures.","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 8","pages":"590-599"},"PeriodicalIF":1.7,"publicationDate":"2025-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144835486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Wound dressings protect against bacterial environment: results of a prospective clinical study. 伤口敷料防止细菌环境：一项前瞻性临床研究的结果。

IF 1.7 4区医学

Journal of wound care Pub Date : 2025-08-02 DOI: 10.12968/jowc.2024.0043

Maurice Moelleken, Sebastian Heinrich Krimphove, Frederik Krefting, Christos Rammos, Anna Ewa Cyrek, Sven Benson, Joachim Dissemond

{"title":"Wound dressings protect against bacterial environment: results of a prospective clinical study.","authors":"Maurice Moelleken, Sebastian Heinrich Krimphove, Frederik Krefting, Christos Rammos, Anna Ewa Cyrek, Sven Benson, Joachim Dissemond","doi":"10.12968/jowc.2024.0043","DOIUrl":"10.12968/jowc.2024.0043","url":null,"abstract":"Objective: Numerous bacteria are found in almost all wounds. Multidrug-resistant bacteria are a particular challenge. Wound dressings are primarily intended to improve wound healing. Their protective function for the environment and other people from the potentially pathogenic bacteria has been little studied. The aim of this cross-sectional study was to investigate the effectiveness of wound dressings in protecting the environment from bacterial contamination in a prospective clinical study within routine care.Method: Patients with wounds of different types were studied in an interdisciplinary certified wound care centre. Examinations were performed during routine patient visits. Wound-related data were collected and fluorescence images of all wounds, wound dressings and wound exteriors were taken.Results: Of the 151 patients included, 68 (45%) were male and 83 (55%) were female. The wound duration ranged from 1-1399 weeks, with 77.5% being hard-to-heal (chronic) wounds. Wound care was provided by an ambulatory care service for 75 (49.7%) patients and by the patients themselves in 76 (50.3%) cases. A total of 67 (44.4%) patients used antimicrobial wound therapy. Using fluorescence photography, bacterial colonisation could be detected in 62 (41.1%) wounds; on the inner side of the wound dressings it was detectable in 19 (13.1%) and on the outside only in one wound dressing which had been incorrectly applied.Conclusion: In this study, both antimicrobial and non-antimicrobial dressings were shown to provide an effective barrier to bacterial penetration through the dressings when applied correctly. This ensured adequate protection of the environment and others from bacterial contamination when modern dressings were used correctly.","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 8","pages":"564-570"},"PeriodicalIF":1.7,"publicationDate":"2025-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144835509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0