Journal of wound care最新文献_第3页

Use of a next-generation multilayered foam dressing in hard-to-heal wounds: a prospective, multicentre study.

IF 1.5 4区医学

Journal of wound care Pub Date : 2025-02-02 Epub Date: 2025-01-27 DOI: 10.12968/jowc.2024.0416

Marisa Ranire-Maguire, Russell Caprioli, Cristin Taylor, Rebecca Rodger, Andrew Thomas, Alisha Oropallo

{"title":"Use of a next-generation multilayered foam dressing in hard-to-heal wounds: a prospective, multicentre study.","authors":"Marisa Ranire-Maguire, Russell Caprioli, Cristin Taylor, Rebecca Rodger, Andrew Thomas, Alisha Oropallo","doi":"10.12968/jowc.2024.0416","DOIUrl":"https://doi.org/10.12968/jowc.2024.0416","url":null,"abstract":"Objective: Hard-to-heal wounds present a significant healthcare challenge due to their complex aetiology, impact on quality of life (QoL) and consequent economic burden. The aim of this study was to assess the usability, safety and performance of a next-generation, multilayered foam dressing, ConvaFoam (Convatec Ltd., UK), in the management of indicated hard-to-heal wounds.Method: In this prospective, multicentre, interventional, non-comparator, open-label study, wounds included venous leg ulcers, arterial leg ulcers, diabetic foot ulcers and pressure injuries. The primary endpoint was percentage change in wound area at four weeks. Additional endpoints included percentage change in wound area at 12 weeks, satisfactory clinical progress (defined as ≥40% reduction in study wound area at four weeks), complete wound closure, adverse events, pain, QoL and health professional usability outcomes.Results: A total of 90 patients (109 wounds) were included in the full analysis set. The median percentage reduction in wound area from baseline was 47.88% (p<0.0001) at week 4 and 93.75% (p<0.0001) at week 12. Satisfactory clinical progress at four weeks was reported for 61 (55.96%) wounds. Complete wound closure by week 12 was observed in 43 (39.45%) wounds (p<0.0001). The median Wound Quality of Life-14 score improved from 55.36 at baseline, to 80.36 at week 12. Of the 2935 dressing applications, there were only two adverse events which were reported to be related to the study dressings. The majority of health professionals rated ease of application, exudate management, ease of removal and conformity as excellent.Conclusion: The ConvaFoam dressings were shown to be effective at reducing wound size and promoting healing in indicated hard-to-heal wounds, particularly diabetic foot and venous ulcers.","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 2","pages":"154-162"},"PeriodicalIF":1.5,"publicationDate":"2025-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143390366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of a caregiver of a patient with venous leg ulcers in recurrence prevention: a case study.

IF 1.5 4区医学

Journal of wound care Pub Date : 2025-02-02 DOI: 10.12968/jowc.2022.0128

Anna Karafová, Agnieszka Siemieniecka, Marian Karafa

{"title":"The role of a caregiver of a patient with venous leg ulcers in recurrence prevention: a case study.","authors":"Anna Karafová, Agnieszka Siemieniecka, Marian Karafa","doi":"10.12968/jowc.2022.0128","DOIUrl":"https://doi.org/10.12968/jowc.2022.0128","url":null,"abstract":"Objective: Venous leg ulcer (VLU) is a common complication which significantly reduces the patient's quality of life. Despite many effective treatment methods, such as compression therapy, which allow the wound to heal in a short time, it is important to maintain the long-term effects of the therapy. We present the case of a 67-year-old male patient with a trophic ulcer of his left leg.Method: The patient was treated with inelastic multicomponent compression bandages applied every day under Kikuhime pressure-measuring device (HPM-KH-01; TT Meditrade, Denmark) control and advised to wear a compression stocking.Results: The patient's wound closed within eight weeks. After five months, the patient returned to our clinic with a one-month-old wound due to non-adherence with medical recommendations.Conclusion: Key roles in recurrence prevention seem to be played not only by the patient's motivation and perseverance, but, more importantly, by the approach of the therapist. Health professionals should focus not only on one-time closure of the patient's wound, but on cooperation with the patient's family and caregivers, and instructing them on how to look after the patient on a daily basis, including with help to put on compression garments and with motivation to move and exercise. In many cases, with unaccompanied patients, rapid VLU recurrence is observed.","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 2","pages":"128-132"},"PeriodicalIF":1.5,"publicationDate":"2025-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143389961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Appreciating the past but focusing on the future: specialist nurses in wound care in Europe.

IF 1.5 4区医学

Journal of wound care Pub Date : 2025-02-02 DOI: 10.12968/jowc.2025.0008

Corinne Scicluna Ward

引用次数: 0

Hippophae rhamnoides L. leaf extract augments dermal wound healing in streptozocin-induced diabetic rats.

IF 1.5 4区医学

Journal of wound care Pub Date : 2025-02-02 DOI: 10.12968/jowc.2021.0309

Nitin K Upadhyay, Gaurav K Keshri, Asheesh Gupta

{"title":"Hippophae rhamnoides L. leaf extract augments dermal wound healing in streptozocin-induced diabetic rats.","authors":"Nitin K Upadhyay, Gaurav K Keshri, Asheesh Gupta","doi":"10.12968/jowc.2021.0309","DOIUrl":"https://doi.org/10.12968/jowc.2021.0309","url":null,"abstract":"Objective: The present investigation was undertaken to determine the healing efficacy of Hippophae rhamnoides L. (sea buckthorn (SBT)) leaf aqueous lyophilised extract (SBTL-ALE) on a diabetic wound model in rats. The effect of SBTL-ALE was also evaluated on human epithelial cell lines (A431) by using in vitro wound closure and transwell migration assays.Method: A total of four full-thickness excision-type wounds were created on the dorsal surface of streptozocin-induced diabetic rats. The animals were divided into two groups: control rats treated with soft white petroleum jelly and experimental rats treated with SBTL-ALE (5.0%, weight/weight) ointment applied topically, twice daily for seven days.Results: SBTL-ALE significantly (p<0.05) accelerated the migration of epithelial cells in in vitro wound closure and transwell migration assays. Further, SBTL-ALE augmented the healing process by significantly (p<0.05) enhanced wound area contraction, faster complete epithelial closure, increased hydroxyproline (collagen) and hexosamine levels in diabetic rats. Histopathological findings confirmed the healing potential of SBTL-ALE. Immunohistochemical analyses showed increased expression of transforming growth factor (TGF)-β and α-smooth muscle actin in SBTL-ALE-treated wounds of diabetic rats. Superoxide dismutase, catalase and reduced glutathione levels increased, whereas reactive oxygen levels were decreased significantly (p<0.05) in SBTL-ALE-treated wounds compared to diabetic controls, which conferred redox homeostasis.Conclusion: Our results suggest that SBTL-ALE accelerated transdermal wound healing in diabetic rats by increasing the rate of wound contraction, enhancing levels of collagen, hexosamine and endogenous antioxidants, and reducing oxidative stress.","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 2","pages":"146-153"},"PeriodicalIF":1.5,"publicationDate":"2025-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143391132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ulcerated tophaceous gout of the foot: a case report and retrospective chart review.

IF 1.5 4区医学

Journal of wound care Pub Date : 2025-02-02 DOI: 10.12968/jowc.2022.0166

Laura Iglesias-Girard, Justine Lafleur-Careau, Jérôme Patry

引用次数: 0

Pressure injury detection using alternate light: a proof-of-concept study.

IF 1.5 4区医学

Journal of wound care Pub Date : 2025-02-01 DOI: 10.12968/jowc.2023.0304

Katherine N Scafide, Linda Arundel, Ghadeer Assas, Erica L King

{"title":"Pressure injury detection using alternate light: a proof-of-concept study.","authors":"Katherine N Scafide, Linda Arundel, Ghadeer Assas, Erica L King","doi":"10.12968/jowc.2023.0304","DOIUrl":"https://doi.org/10.12968/jowc.2023.0304","url":null,"abstract":"Objective: Identification of early-stage pressure injuries (PIs) during visual skin assessment may be subjective and unreliable. An alternate light source (ALS) has been shown to increase the probability of detecting evidence of bruises on individuals with darker skin tones. Bruises and early-stage PIs are often difficult to identify, especially in those with darker skin tones, where melanin concentration is high. Given the effect skin pigmentation has on detecting both types of cutaneous injuries, this proof-of-concept study aimed to describe the characteristics of Stage 1 PIs and deep tissue PIs as viewed under an ALS.Method: Eligible participants were first examined by a certified wound ostomy continence nurse using environmentally available white light. A blinded second examiner then evaluated the size of the potential tissue impairment using violet (406nm) and blue (448nm) ALS viewed through yellow and orange goggles, respectively. Portable ultrasound was used to confirm tissue involvement. Data were summarised using descriptive statistics.Results: The study included 10 participants (40% of whom were from minority racial/ethnic groups) with a mean Braden Scale score of 11.1. The majority of PIs (80%) involved deep tissue and were located on lower extremities (60%). The median PI size was larger by 17.5cm2 and 13.7cm2, respectively, using ALS compared with white light when viewed under violet and blue wavelengths. Ultrasound data were limited to non-extremity regions (n=3 participants) with hypoechoic areas noted as being 10-13mm in thickness and up to 16.7mm deep.Conclusion: Evidence of tissue damage that extended beyond that visualised under white light was noted with ALS. Usefulness of ultrasound was limited over bony prominences where there was too little subcutaneous tissue. Further research is warranted to investigate the potential application of ALS for the early detection of PIs.","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 Sup2","pages":"S17-S23"},"PeriodicalIF":1.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143390861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relationship of opioid tolerance to patient and wound factors, and wound micro-environment in patients with open wounds.

IF 1.5 4区医学

Journal of wound care Pub Date : 2025-02-01 DOI: 10.12968/jowc.2023.0215

Jaewon Bae, Amy Campbell, Maria Hein, Stephen L Hillis, Elizabeth Grice, Barbara A Rakel, Sue E Gardner

{"title":"Relationship of opioid tolerance to patient and wound factors, and wound micro-environment in patients with open wounds.","authors":"Jaewon Bae, Amy Campbell, Maria Hein, Stephen L Hillis, Elizabeth Grice, Barbara A Rakel, Sue E Gardner","doi":"10.12968/jowc.2023.0215","DOIUrl":"https://doi.org/10.12968/jowc.2023.0215","url":null,"abstract":"Objective: Opioid tolerance is a criterion for opioid use disorder, which is currently an epidemic in the US. Individuals with open wounds are frequently administered opioids; however, the phenomenon of opioid tolerance has not been examined in the context of wounds. The purpose of this exploratory study was to compare patient/wound factors, wound microbiome and inflammatory mediators between individuals who were opioid-tolerant versus those who were not opioid-tolerant.Method: Patients with acute open wounds were enrolled in this cross-sectional study. All study data were collected before and during a one-time study dressing change.Results: The study included a total of 385 participants. Opioid-tolerant participants were significantly younger (p<0.0001); had higher levels of depression (p=0.0055) and anxiety (p=0.0118); had higher pain catastrophising scores (p=0.0035); reported higher resting wound pain (p<0.0001); had a higher number of wounds of <30 days' duration (p=0.0486); and had wounds with lower bacterial richness (p=0.0152) than participants who were not opioid-tolerant. A backward elimination logistic regression model showed that four predictors-resting wound pain, age, bacterial richness and depression-were the most important variables in predicting opioid-tolerance status.Conclusion: These findings provide the first insights into the phenomenon of opioid tolerance in the context of open wounds. This study provides findings from which to guide hypothesis-driven research in the future.","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 Sup2","pages":"S6-S16"},"PeriodicalIF":1.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143391083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Progressive bacterial synergistic gangrene (Meleney's gangrene): a rare case.

IF 1.5 4区医学

Journal of wound care Pub Date : 2025-02-01 DOI: 10.12968/jowc.2020.0119

Fatma Bilgen, Alper Ural, Mehmet Bekerecioglu

引用次数: 0

Improving partial-thickness burn pain and outcomes using cultured epithelial allografts or highly concentrated surfactant-based dressings.

IF 1.5 4区医学

Journal of wound care Pub Date : 2025-02-01 DOI: 10.12968/jowc.2023.0282

Melinda Nguyen, Joanna Chen, Taylor Spurgeon-Hess, Jun Kyoung, Richard Simman

{"title":"Improving partial-thickness burn pain and outcomes using cultured epithelial allografts or highly concentrated surfactant-based dressings.","authors":"Melinda Nguyen, Joanna Chen, Taylor Spurgeon-Hess, Jun Kyoung, Richard Simman","doi":"10.12968/jowc.2023.0282","DOIUrl":"https://doi.org/10.12968/jowc.2023.0282","url":null,"abstract":"Objective: The prevention and treatment of burn wounds has improved over the years, leading to decreased incidence, severity and mortality. However, burn injuries, particularly partial-thickness burns, have a painful treatment course which, if not optimised, can cause undue suffering to patients and prolonged recovery. Although silver sulfadiazine has been the most commonly accepted treatment for partial-thickness burns due to its strong hindrance of infection, wide availability and low cost, it requires daily dressing changes which are labour intensive and painful. Exploring alternative techniques, such as using cultured keratinocytes, to prevent and treat burn wounds may provide a path to better optimising the path to recovery.Method: This paper presents two cases that use two alternative treatments, either PluroGel (a gel surfactant, Medline Industries, US) or cultured keratinocytes, in the treatment of partial-thickness burns to minimise pain and enhance treatment experience.Results: Using surfactant-based treatments, such as the gel surfactant, in partial-thickness burns exhibited prohealing outcomes via enhanced antimicrobial effects, a strengthened physical barrier and cell salvage.Conclusion: Using cultured keratinocytes and a highly concentrated surfactant may achieve more rapid re-epithelialisation of partial-thickness burn wounds. These alternative techniques may offer significant advancement in the quality of care in burn injury treatment.","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 Sup2","pages":"S27-S32"},"PeriodicalIF":1.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143390803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Psychological, behavioural and relevant factors affecting wound healing, and the buffering role of interventions.

IF 1.5 4区医学

Journal of wound care Pub Date : 2025-02-01 DOI: 10.12968/jowc.2020.0222

Masoud Irani, Soheila Salahshour Kordestani

引用次数: 0