Treatment of chronic wounds with cold plasma: a randomised, single-blind, placebo-controlled clinical study.

IF 1.7 4区医学 Q3 DERMATOLOGY

Journal of wound care Pub Date : 2025-08-02 Epub Date: 2025-07-28 DOI:10.12968/jowc.2025.0207

Robert Strohal, Martina Mittlböck, Lisa Gebhardt, Gilbert Hämmerle

引用次数: 0

Abstract

Objective: This study aimed to investigate the wound healing properties of cold atmospheric plasma (CAP) in patients with chronic wounds.

Method: This was a prospective, multicentre, two-arm, randomised, single-blind clinical study which compared the wound healing treatment of CAP with placebo, both of which were combined with best practice wound care.

Results: The study cohort consisted of 70 patients: 35 in the CAP group and 35 in the placebo group. There was a statistically significant (p<0.0001) reduction in the wound area at the end of the study, and faster wound healing, with the use of CAP compared with a placebo device.

Conclusion: The results of this study showed that without requiring adjunctive therapies, the CAP device represents a safe, well-tolerated, and highly effective therapeutic option for wounds in that it promotes their rapid healing.

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低温等离子体治疗慢性伤口：一项随机、单盲、安慰剂对照临床研究。

目的：探讨低温常压等离子体（CAP）在慢性创面愈合中的作用。方法：这是一项前瞻性，多中心，双组，随机，单盲临床研究，比较CAP与安慰剂的伤口愈合治疗，两者都结合了最佳实践伤口护理。结果：研究队列包括70例患者：CAP组35例，安慰剂组35例。结论：本研究结果表明，在不需要辅助治疗的情况下，CAP装置可以促进伤口快速愈合，是一种安全、耐受性良好、高效的伤口治疗选择。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of wound care DERMATOLOGY-

CiteScore

2.90

自引率

10.50%

发文量

215

期刊介绍： Journal of Wound Care (JWC) is the definitive wound-care journal and the leading source of up-to-date research and clinical information on everything related to tissue viability. The journal was first launched in 1992 and aimed at catering to the needs of the multidisciplinary team. Published monthly, the journal’s international audience includes nurses, doctors and researchers specialising in wound management and tissue viability, as well as generalists wishing to enhance their practice. In addition to cutting edge and state-of-the-art research and practice articles, JWC also covers topics related to wound-care management, education and novel therapies, as well as JWC cases supplements, a supplement dedicated solely to case reports and case series in wound care. All articles are rigorously peer-reviewed by a panel of international experts, comprised of clinicians, nurses and researchers. Specifically, JWC publishes: High quality evidence on all aspects of wound care, including leg ulcers, pressure ulcers, the diabetic foot, burns, surgical wounds, wound infection and more The latest developments and innovations in wound care through both preclinical and preliminary clinical trials of potential new treatments worldwide In-depth prospective studies of new treatment applications, as well as high-level research evidence on existing treatments Clinical case studies providing information on how to deal with complex wounds Comprehensive literature reviews on current concepts and practice, including cost-effectiveness Updates on the activities of wound care societies around the world.