Journal of wound care最新文献

{"title":"Exudate management with a next-generation multilayered foam dressing in traumatic and surgical wounds: a prospective, multicentre study.","authors":"Marisa Ranire-Maguire, Russell Caprioli, Cristin Taylor, Rebecca Rodger, Andrew Thomas, Alisha Oropallo","doi":"10.12968/jowc.2026.0048","DOIUrl":"https://doi.org/10.12968/jowc.2026.0048","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to evaluate the efficacy, performance and safety of ConvaFoam (Convatec Ltd., UK), a next-generation multilayered foam dressing, in indicated surgical and traumatic wounds.</p><p><strong>Method: </strong>This prospective, multicentre, open-label study (ClinicalTrials.gov: NCT05632276) evaluated ConvaFoam dressings in surgical and traumatic wounds. Eligible patients were managed with ConvaFoam dressings in accordance with their instructions for use (maximum seven-day wear time) for ≤4 weeks. The primary endpoint was the proportion of patients and total dressings with excellent exudate management (defined as absence of strikethrough or periwound maceration). Secondary endpoints included: exudate management in dressings worn for seven days; healing rate; wear time; pain on application; usability; and safety.</p><p><strong>Results: </strong>The study enrolled 52 patients (mean age: 48.2 years) with surgical (54%) or traumatic (46%) wounds. Median dressing wear time was five days (interquartile range: 1-7 days). Among patients who completed the study, 81% (38/47) were observed to have achieved excellent exudate management throughout all wound care visits (90% confidence interval (CI): 71, 90%). Excellent exudate management was also observed in 93% (209/224) of total dressings applied (90% CI: 90, 97%), including in 96% (47/49) of dressings worn for seven days. Only one patient in the study experienced periwound skin maceration at any study timepoint. Wound healing was observed in 93% of surgical wounds and 25% of traumatic wounds during the study period. Low levels of pain and high user satisfaction as per numeric pain scale and utility questionnaire, respectively, were reported.</p><p><strong>Conclusion: </strong>ConvaFoam dressings demonstrated excellent exudate management in >90% of dressing changes, and may promote an optimal environment for healing in surgical and traumatic wounds.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"35 5","pages":"392-398"},"PeriodicalIF":1.7,"publicationDate":"2026-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147816521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Breaking the cycle of hard-to-heal wounds: the role of autologous whole blood clot therapy.","authors":"Robert J Snyder","doi":"10.12968/jowc.2025.0325","DOIUrl":"https://doi.org/10.12968/jowc.2025.0325","url":null,"abstract":"<p><p>Hard-to-heal (chronic) wounds pose significant challenges in healthcare due to their prolonged inflammatory phase and impaired healing processes. These wounds, commonly associated with diabetes, vascular insufficiency or impaired mobility, fail to progress through the orderly phases of haemostasis, inflammation, proliferation and remodelling. Persistent inflammation, driven by M1 macrophages, neutrophils and proteases, disrupts extracellular matrix (ECM) reconstruction and degrades growth factors and cytokines, halting healing. Conventional treatments often fail to address the underlying pathophysiology, prompting interest in advanced autologous therapies. Autologous whole blood clot (AWBC), an innovative autologous therapy, activates the patient's blood to create a biological scaffold rich in growth factors and cytokines. This scaffold promotes wound healing by supporting ECM reconstruction, causing inflammatory M1 macrophages to transition to regenerative M2 macrophages, and enhancing neutrophil clearance. The objective of this review was to summarise the current clinical evidence and elucidate the proposed biological mechanisms by which AWBC promotes healing in hard-to-heal wounds. Clinical studies have demonstrated AWBC's efficacy across multiple wound types, including diabetic foot ulcers, pressure ulcers and surgical wounds. With a robust safety profile, minimal risk of adverse reactions and reported efficacy, AWBC offers a transformative solution for hard-to-heal wound management, addressing unmet clinical needs and improving patient outcomes.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"35 5","pages":"409-415"},"PeriodicalIF":1.7,"publicationDate":"2026-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147816569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Developing and implementing a pressure ulcer prevention strategy: protocol of a quasi-experimental study in Slovakia.","authors":"Lucia Dimunová, Beáta Grešš Halász, Ivana Židovská","doi":"10.12968/jowc.2024.0105","DOIUrl":"https://doi.org/10.12968/jowc.2024.0105","url":null,"abstract":"<p><strong>Objective: </strong>Pressure ulcers (PUs) are a health complication that is largely preventable (80-95%) and which has a physical, psychological and socioeconomic impact on the individual and on their family. The worldwide prevalence is between 5-27% and the cost of treatment is more than twice the cost of prevention. Due to the inconsistency of preventive measures at the national level, Louis Pasteur University Hospital in Košice, the second largest university hospital in Slovakia, in cooperation with the Department of Nursing, Faculty of Medicine, Pavol Jozef Šafárik University in Košice, is implementing a PU prevention strategy, and undertaking data collection and identification of gaps to address PUs.</p><p><strong>Method: </strong>This protocol describes the development of a PU prevention strategy (PUPS) by clinicians and academics from the two institutions, using the EPUAP/NPIAP/PPPIA 2019 international guideline, and its planned implementation into clinical practice.</p><p><strong>Results: </strong>The preliminary testing of PUPs involved 60 patients, of whom 28 were at very high risk of PU development, positively correlating with age (p=0.002). Patients at very high-risk were found to receive care more consistently compared to high- and medium-risk patients. In the planned research, demographic data and sample characteristics in relation to the level of risk and the performed/missed preventive measures will be statistically analysed and evaluated. The success of the prevention strategy will be evaluated based on hospital-acquired pressure ulcer (HAPU) statistics, and characteristics before and after the implementation of PUPS.</p><p><strong>Conclusion: </strong>PUPS is the result of a collaboration between the academic institution and the hospital that integrates and links education, research, evidence and practice to improve outcomes for patients, and streamline the work of healthcare professionals. In view of the results of the strategy's pre-testing, it is believed that the planned research will reveal the shortcomings of implementing preventive strategies in detail, and allow those responsible to focus specifically on the improvement plan. In addition, the electronic format of the PUPS will be used to collect and summarise statistical data on HAPUs, which is lacking in Slovakia. This strategy has the potential to improve standards of PU prevention and quality of care assessment, based on the principles of evidence-based practice at the national level in Slovakia. Systematic prevention strategies lead to satisfactory outcomes in the context of targeting deficiencies, managing workload, reducing PUs and costs, improving quality and safety of care, and increasing patient satisfaction. The implementation of an easy-to-use protocol is a pilot project at national level. The aim is to incorporate the strategy into national standards and potentially recommend it at international level.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"35 5","pages":"445-453"},"PeriodicalIF":1.7,"publicationDate":"2026-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147816562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reassessing the vascular basis of pelvic pressure injuries: the case for pelvic arterial evaluation.","authors":"Igor Melnychuk","doi":"10.12968/jowc.2026.0148","DOIUrl":"https://doi.org/10.12968/jowc.2026.0148","url":null,"abstract":"","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"35 5","pages":"351-352"},"PeriodicalIF":1.7,"publicationDate":"2026-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147816693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Palliative care nurses' knowledge of the assessment and management of malignant fungating wounds: a scoping review.","authors":"Eimer Noone, Michael Connolly","doi":"10.12968/jowc.2023.0124","DOIUrl":"https://doi.org/10.12968/jowc.2023.0124","url":null,"abstract":"<p><strong>Objective: </strong>The aim of the review was to develop a greater understanding of nurses' knowledge of wound assessment and management, paying particular attention to malignant fungating wounds (MFWs), and to identify and explore the evidence on these wounds and their treatment.</p><p><strong>Method: </strong>A scoping review was conducted to search for and select potential studies. A search was undertaken using CINAHL, PubMed, Cochrane, Scopus and Google Scholar. The scoping review was guided by the framework of Arskey and O'Malley.</p><p><strong>Results: </strong>Following review, three studies met the inclusion criteria and were ultimately selected for data extraction. The four main themes developed from analysis included: prevalence of MFWs; impact on the individual/caregiver/nurse; symptom management in MFWs; and lack of knowledge and skills.</p><p><strong>Conclusion: </strong>The findings of this review highlighted that there is a clear lack of evidence, despite the plethora of published literature on general wound assessment and management, to adequately determine nurses' knowledge of the assessment and management of MFWs. This indicates that a greater focus needs to be placed on attaining knowledge if holistic care is to be provided. There is a need for specific knowledge in nursing, and so, greater attention is needed to improve nurses' knowledge in carrying out MFW assessment and management, and in developing and advancing nursing research practice in the field of palliative wound care.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"35 5","pages":"416-423"},"PeriodicalIF":1.7,"publicationDate":"2026-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147816619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence and risk factors of medical adhesive-related skin injury among ICU patients: a systematic review and meta-analysis.","authors":"Yaying Xu, Meiqiong Yan, Wenyan Pan, Chunlei Li","doi":"10.12968/jowc.2024.0404","DOIUrl":"https://doi.org/10.12968/jowc.2024.0404","url":null,"abstract":"<p><strong>Objective: </strong>To summarise the evidence regarding the incidence and risk factors of medical adhesive-related skin injury (MARSI) among patients in the intensive care unit (ICU).</p><p><strong>Method: </strong>A systematic review and meta-analysis was undertaken using articles available in nine databases: PubMed; the Cochrane Library; Web of Science; Embase; CINAHL; Chinese Biomedical Literature Database; China National Knowledge Infrastructure Database; Wanfang Database; and Weipu Database, from inception until 30 June 2024. Additional studies were identified by examining the references of relevant articles. The Stata 16.0 statistical platform (StataCorp LLC, US) was used for analysis. Study quality was assessed using the Newcastle-Ottawa Scale and the Agency for Healthcare Research and Quality standards.</p><p><strong>Results: </strong>Of 14,743 titles screened, 19 studies involving 5218 patients were included in the systematic review. The pooled incidence of MARSI was 21% (95% confidence interval (CI): 14%, 28%), and the incidence of MARSI among neonatal ICU, paediatric ICU and adult ICU was 15% (95% CI: 6%, 26%), 48% (95% CI: 35%, 60%) and 16% (95% CI: 11%, 22%), respectively. Significant risk factors in adult ICUs included oedema (odds ratio (OR): 8.144; 95%CI: 3.267, 20.304), Braden scale score (OR: 0.733; 95%CI: 0.641, 0.837), length of ICU stay (OR: 1.072; 95%CI: 1.026, 1.120), mechanical ventilation (OR: 3.698; 95%CI: 1.900, 7.199), sedative use (OR: 6.022; 95%CI: 2.859, 12.687), Nutritional Risk Screening 2002 score (OR: 4.241; 95%CI: 1.984, 9.065) and hypoalbuminaemia (OR: 4.321; 95%CI: 1.967, 9.488).</p><p><strong>Conclusion: </strong>This study found that MARSI is prevalent among ICU patients and is associated with multiple risk factors. Improved strategies for identifying and clinically managing MARSI in ICU patients are needed. Nevertheless, large-sample and multicentre studies are still warranted to validate the present study's findings.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"35 5","pages":"428-437"},"PeriodicalIF":1.7,"publicationDate":"2026-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147816685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Addressing wound healing barriers to optimise wound progression: investigating the advanced benefits of a next-generation multilayer foam dressing.","authors":"Karen Ousey, Kamaluddeen Garba, Bashir Lwaleed, Daniel Fitzgerald, Damaris Williams, Jessica Winks, Varuni Brownhill, Peter Worsley","doi":"10.12968/jowc.2026.0135","DOIUrl":"https://doi.org/10.12968/jowc.2026.0135","url":null,"abstract":"<p><strong>Objective: </strong>Excess wound exudate can cause tissue maceration and delayed healing. Fluctuating exudate levels, combined with the impact of gravity, increase dressing leakage risk, affecting patient quality of life. Bacteria and proteases found in hard-to-heal (chronic) wounds pose additional barriers to healing if not promptly removed. Absorbent dressings must therefore address these multiple challenges, and so were explored in this series of preclinical investigations.</p><p><strong>Method: </strong>Standard in vitro absorbency tests were conducted to compare the performance of several dressings with a new advanced five-layer silicone polyurethane foam dressing with superabsorbent particles (ASFS). Dressing functionality was explored using clinically relevant test conditions, including the impact of gravity and fluid bolus events on absorbency, combined with the dressing's ability to absorb and retain bacteria and proteases.</p><p><strong>Results: </strong>ASFS demonstrated superior performance across standard absorbency tests versus most of the alternative absorbent dressings and outperformed a comparator five-layer silicone foam dressing with superabsorbent fibres (SFD) in run-off testing. Under clinically relevant dynamic bolus conditions, including gravitational challenge, no leakage was observed with ASFS, whereas dressing failure due to fluid spill or leakage was observed with SFD. ASFS was also shown to retain matrix metalloproteinases and the majority of bacteria, even under increasing fluid volumes.</p><p><strong>Conclusion: </strong>Functionality of absorbent wound dressings in both standard and clinically relevant tests is critical to support healthcare professionals' decision-making in selecting optimal interventions for their patients' wounds. Effective exudate management combined with removal of bacteria and proteases by the new ASFS dressing supports healthcare professional and patient confidence in continuing with daily activities, with the potential for fewer dressing changes and associated resource benefits, warranting further evaluation in clinical practice.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"35 5","pages":"365-376"},"PeriodicalIF":1.7,"publicationDate":"2026-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147816588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinician decision-making for transitioning to single-use negative pressure wound therapy: analysis of real-world practice in an acute setting.","authors":"Connie Johnson, Mandy Spitzer, Sophie Berry, Jonathan Minton","doi":"10.12968/jowc.2025.0579","DOIUrl":"https://doi.org/10.12968/jowc.2025.0579","url":null,"abstract":"<p><strong>Objective: </strong>Despite the widespread adoption of traditional negative pressure wound therapy (tNPWT) to improve clinical outcomes for hard-to-heal (chronic) wounds and the increasing availability of single-use systems that improve patient acceptability, there is limited evidence published about when to use each type of system to optimise treatment pathways. The aim of this retrospective case review was to evaluate those wounds transitioned from tNPWT to single-use NPWT (sNPWT) in a real-world, acute care setting and review clinical outcomes, thereby informing future practice approaches.</p><p><strong>Method: </strong>A retrospective chart review of the treatment pathway and clinical outcomes of all patients with wounds managed using NPWT presenting at a single, acute care hospital in the US from February 2023 to September 2024 was conducted. Initial tNPWT was administered continually at either -80mmHg or -120mmHg for all wounds. Wound characteristics and healing outcomes for patients transitioned from tNPWT to sNPWT during the course of treatment were reviewed.</p><p><strong>Results: </strong>Electronic medical records of 27 patients (12 females, 15 males; with 70% aged 36-75 years) with wounds that were eligible for treatment with NPWT were available for review. Mean duration of tNPWT and sNPWT was 9.8±11.1 days (median: 7 days; range: 3-60 days). Estimated daily mean wound area reduction was 5.8% (median value: 3.2%) with similar improvements noted for wound volume. Of the 27 wounds treated with tNPWT, eight were successfully transitioned to sNPWT once a sustained healing trajectory had been achieved. No wounds received first-line treatment with sNPWT, despite many of the wounds potentially being suitable for this approach.</p><p><strong>Conclusion: </strong>Approximately 30% of wounds included in this review were considered eligible for transition from tNPWT to sNPWT, facilitating earlier hospital discharge without compromising clinical outcomes. More widespread adoption of sNPWT, and even first-line use for appropriate wounds, may help to reduce hospital stay while maintaining effective wound management, thereby improving the patient experience, hospital efficiency and resource utilisation.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"35 5","pages":"400-408"},"PeriodicalIF":1.7,"publicationDate":"2026-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147816601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Defining appropriate CAMPs administration: a response to the Medicare wastage guidance.","authors":"Shaun Carpenter, Windy Cole","doi":"10.12968/jowc.2026.0111","DOIUrl":"https://doi.org/10.12968/jowc.2026.0111","url":null,"abstract":"","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"35 5","pages":"353-354"},"PeriodicalIF":1.7,"publicationDate":"2026-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147816551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison between foam dressings impregnated with ionic silver and silver sulfadiazine cream 1% in treating deep burns.","authors":"Juliano Baron Almeida, Pedro Soler Coltro, Altacilio Aparecido Nunes, Jayme Adriano Farina","doi":"10.12968/jowc.2024.0071","DOIUrl":"https://doi.org/10.12968/jowc.2024.0071","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this trial was to evaluate the effectiveness of foam dressings impregnated with ionic silver (AgF) compared to the traditional treatment of 1% silver sulfadiazine cream (SSD) in deep burns (deep dermal and full-thickness burns) and assess the cost-effectiveness ratio between the two treatments.</p><p><strong>Method: </strong>This was a randomised clinical trial of patients who were divided into two equal-sized treatment groups: Group 1-SSD or Group 2 - AgF. Inclusion criteria were patients aged between 18-60 years with burns of thermal origin affecting 10-30% of the body surface area, and with a comparable percentage of deep burns. The following outcomes were analysed: pain; discomfort; wound infection; need for new grafting; ease of dressing application; length of stay; and cost of treatment.</p><p><strong>Results: </strong>A total of 40 patients took part (20 in each group). Regarding patients' experience of pain, data analysis revealed more effective pain control in patients treated with AgF. Additionally, the AgF dressing was considered safer, more comfortable and presented an average lower cost of 30.6% compared to the SSD.</p><p><strong>Conclusion: </strong>The findings of this trial showed that, compared to the SSD, the AgF dressings were more effective in treating deep burns, to prepare them for skin graft surgery.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"35 5","pages":"438-444"},"PeriodicalIF":1.7,"publicationDate":"2026-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147816536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}