Journal of wound care最新文献

{"title":"Bovine-derived collagen matrix as an adjunct in stage 3 pressure injuries: a case series of lower extremity wounds.","authors":"Scott R Boynton, Melina Butuci, R Allyn Forsyth, Sara Shahbazi","doi":"10.12968/jowc.2025.0254","DOIUrl":"10.12968/jowc.2025.0254","url":null,"abstract":"<p><strong>Objective: </strong>Hard-to-heal (chronic) stage 3 pressure injuries (PIs) in medically complex patients are often refractory to standard treatments, and pose significant risks of infection, limb loss and diminished quality of life. Adjunctive use of advanced biologic materials, such as bovine-derived collagen matrices, may support more efficient wound resolution in these high-risk populations.</p><p><strong>Method: </strong>In this retrospective case series, patients with hard-to-heal stage 3 PIs of the lower extremity were treated with a single application of a bovine-derived collagen matrix as part of a multidisciplinary wound care protocol. All patients had significant comorbidities, including diabetes and dementia, as well as mobility impairments, such as peripheral neuropathy and multiple sclerosis with paraplegia. Interventions included debridement, a single application of a bovine-derived collagen matrix, appropriate wound dressings and pressure offloading.</p><p><strong>Results: </strong>All three patients (each with one PI) had failed to respond to prior standard wound care and their PIs had persisted from four weeks to approximately three years before treatment. Following a single application of the collagen matrix, complete wound closure was achieved within 27-52 days. Early wound responses were notable: one PI showed a 98% area reduction by day 14, another reduced by 76% by day 6, and in Case 2, closed by primary intention, stable closure was observed as early as day 3. No repeat applications of the bovine-derived collagen matrix were required, and no complications or recurrences were observed at follow-up.</p><p><strong>Conclusion: </strong>This case series highlights the potential of bovine-derived collagen matrix as an effective adjunct to comprehensive wound care in medically complex patients with stage 3 PIs that have persisted for several months to years, despite prior standard treatments. In all cases, complete wound closure was achieved following a single application of collagen matrix, highlighting its potential utility in the management of hard-to-heal PIs. Further prospective studies are warranted to validate these outcomes.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 9","pages":"708-716"},"PeriodicalIF":1.7,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145000798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bridging the gap: ICU nurses' experiences in detecting pressure injuries across diverse skin tones.","authors":"Herminigildo Lo, Eleanor Hollywood, Rosemarie Derwin","doi":"10.12968/jowc.2025.0367","DOIUrl":"https://doi.org/10.12968/jowc.2025.0367","url":null,"abstract":"","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 9","pages":"686"},"PeriodicalIF":1.7,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145000852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative evaluation of five pressure injury risk assessment tools in adult ICU patients: a prospective cohort study.","authors":"Bruna Cristina Velozo, Aglecia Moda Vitoriano Budri, Larissa Cristina Bernardo, Meire Cristina Novelli E Castro, Luciana Patricia Fernandes Abbade","doi":"10.12968/jowc.2025.0373","DOIUrl":"https://doi.org/10.12968/jowc.2025.0373","url":null,"abstract":"","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 9","pages":"691"},"PeriodicalIF":1.7,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145000881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"More than just healing: personal stories of digital care and recovery in Norway.","authors":"Ingebjørg Irgens","doi":"10.12968/jowc.2025.0225","DOIUrl":"https://doi.org/10.12968/jowc.2025.0225","url":null,"abstract":"<p><strong>Objective: </strong>Pressure injuries (PIs) remain a significant challenge in both hospital and community-based care in Norway. Despite being largely preventable, their prevalence remains high, with serious consequences for patients, caregivers and the healthcare system. Our digital wound projects have explored the lived experiences, systemic burden, and innovative responses to PI prevention and care, drawing from both quantitative data and qualitative insights.</p><p><strong>Method: </strong>This mixed-methods study combined Norwegian prevalence data with thematic analysis of semi-structured interviews conducted with patients, relatives and district nurses. The qualitative data focused on the experience of patients living with or managing PI, with particular attention to continuity, competence and the role of digital innovation in wound care. A focus group interview with healthcare professionals (HCPs) and a manager discussed implementation barriers to digital innovation.</p><p><strong>Results: </strong>Patients described reduced quality of life due to isolation, and lack of consistent care. Caregivers reported a need for support from wound care specialists. HCPs highlighted challenges including the need for a cooperative financial model to cover increased costs in the municipalities, limited resources, training gaps and fragmented communication across care levels. Digital wound care was positively received, and improved access to the healthcare service, continuity in the service, and patient safety, despite occasional technical issues. However, the current reimbursement model poses financial challenges towards the municipalities.</p><p><strong>Conclusion: </strong>PIs remain a significant clinical and systemic burden in Norway. While digital solutions and national safety initiatives show promise, sustainable improvement requires investment in training, leadership and cross-sector coordination. Patients and nurses emphasised that relational continuity and accessible specialist knowledge were critical to effective PI prevention. This project supports a shift toward integrated, patient-centred wound care models that blend digital innovation with local competence and continuity across care levels. However, the misalignment in costs hinders widespread implementation and perpetuates reliance.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 9","pages":"678-684"},"PeriodicalIF":1.7,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145000937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implementation of pressure monitoring and a risk algorithm to evaluate pre- and post-interventions in the community.","authors":"Silvia Caggiari, Nicci Aylward-Wotton, Peter R Worsley","doi":"10.12968/jowc.2025.0370","DOIUrl":"https://doi.org/10.12968/jowc.2025.0370","url":null,"abstract":"","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 9","pages":"687-688"},"PeriodicalIF":1.7,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145000982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Managing pressure ulcer risk in patients with diabetic neuropathy: a mechanobiological perspective for clinical routine.","authors":"Bérengère Fromy, Antoine Perrier","doi":"10.12968/jowc.2025.0313","DOIUrl":"10.12968/jowc.2025.0313","url":null,"abstract":"<p><p>This article aims to highlight the mechanobiological determinants of foot ulcer risk in diabetic neuropathy. This condition alters sensorimotor control and blunts pressure-induced vasodilation, exposing soft tissues to sustained strain and ischaemia, even without visible deformity. This article presents a narrative clinical review supported by experimental mechanobiology and imaging case studies on diabetic neuropathy. It concludes that ulcer prevention should integrate vascular mechanobiology and biomechanic evaluation into personalised offloading strategies.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 9","pages":"657-664"},"PeriodicalIF":1.7,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145000977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical debridement and type 1 collagen extracellular matrix plus polyhexamethylene biguanide for the management of pressure injuries.","authors":"J Eduardo Melendez, Karla Chavez, Maribel Henao, Cameron DeShazo, Yeabsera Tamire, Jeyantt Srinivas Sankaran, Gabriel Arevalo","doi":"10.12968/jowc.2025.0164","DOIUrl":"https://doi.org/10.12968/jowc.2025.0164","url":null,"abstract":"<p><strong>Objective: </strong>Purified collagen matrix containing a broad-spectrum antimicrobial, polyhexamethylene biguanide (PuraPly Antimicrobial (PCMP); Organogenesis Inc., US) has been shown to be an effective adjunct in managing wounds of different aetiologies. The aim of this study was to show the clinical outcomes of PCMP in the management of pressure injuries (PIs) and its implication on healthcare.</p><p><strong>Method: </strong>This retrospective study included patients managed with PCMP as an adjunct to standard of care procedures, following debridement of stage 3 and stage 4 PIs in the operating room between December 2021-October 2022. Indices from baseline (index surgery) and subsequent visits, including patient demographics, wound presentation and progression were collected and analysed.</p><p><strong>Results: </strong>A total of nine patients with sacral PIs were identified. Of these, six were stage 4 and three were stage 3. Smoking was prevalent in seven patients and five patients had diabetes and were obese. At baseline, the median wound area was 30cm² and bioburden was observed in eight wounds. Following either one or two applications of PCMP, the median wound area was reduced to 16cm² and the incidence of bioburden decreased to one patient.</p><p><strong>Conclusion: </strong>This case series suggested that PCMP is an effective adjunct in the management of PIs by supporting healing and managing bioburden. Wounds managed with PCMP did not require the surgeon's standard protocol of daily enzymatic wound debridement and this may decrease the workload for hospital staff.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 9","pages":"740-746"},"PeriodicalIF":1.7,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145000899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A whole-system responsibility: preventing pressure injuries through strategic management and education.","authors":"Tuija S Ikonen, Jaana Kalliokoski, Sini Eloranta","doi":"10.12968/jowc.2025.0223","DOIUrl":"https://doi.org/10.12968/jowc.2025.0223","url":null,"abstract":"","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 9","pages":"672-675"},"PeriodicalIF":1.7,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145000821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microvascular over-dilation and hypoxia: a potential mechanism for pressure ulcer pathogenesis.","authors":"Petra Korpisalo, Greta Juusola, Galina Wirth, Ivana Kholova, Tarja Tervo-Heikkinen, Ulla-Mari Kinnunen, Seppo Ylä-Herttuala, Heidi Myllykangas, Leena Berg","doi":"10.12968/jowc.2025.0374","DOIUrl":"https://doi.org/10.12968/jowc.2025.0374","url":null,"abstract":"","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 9","pages":"690"},"PeriodicalIF":1.7,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145000924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Moisture-associated skin damage and its management in neonatal and infant populations: a retrospective study in Italy.","authors":"Biagio Nicolosi, Eustachio Parente, Alessio Petronici, Leonardo Fioravanti, Simona Cavalieri, Vincenzo Nobile, Giorgio Reggiardo, Riccardo Coletta, Marco Moroni, Guido Ciprandi","doi":"10.12968/jowc.2025.0178","DOIUrl":"10.12968/jowc.2025.0178","url":null,"abstract":"<p><strong>Objective: </strong>Moisture-associated skin damage (MASD) is a significant concern in the paediatric population, particularly among neonates, who exhibit the highest incidence due to their highly sensitive and fragile skin. The aim of the study was to identify the most effective treatment.</p><p><strong>Method: </strong>A retrospective observational study was conducted at Meyer Children's Hospital IRCCS, Florence, Italy. Data from infants admitted to the neonatal intensive care unit of the hospital were collected from electronic health records. Demographic, clinical and nursing data were analysed to identify the key clinical features of MASD lesions, including their severity, healing time, and the relationship between MASD lesions and treatment approaches.</p><p><strong>Results: </strong>The cohort comprised 102 infants (mean age 2.92 months). Incontinence-associated dermatitis (IAD) accounted for the majority (78.4%) of MASD lesions. Among patients with IAD, most exhibited persistent redness (26.3%) or skin loss (47.5%) without clinical signs of infection. In contrast, peristomal MASD cases constituted 21.6% of the total, with the majority classified according to the Study on Peristomal Skin Alterations (SACS) 2.0 as L2 erosive lesions (63.6%), predominantly occurring in quadrants 2, 3 or 5. A novel treatment (Vulnamin; Professional Dietetics S.p.A., Italy) was used to manage MASD lesions in 64.7% of patients. This innovative treatment significantly (p<0.001) reduced healing time by an average of 2.4 days and decreased the odds of relapse by 5.3 times compared with traditional treatments.</p><p><strong>Conclusion: </strong>The findings of this study showed that use of effective MASD therapies can reduce healing time and relapse rate, leading to decreased nursing hours and associated costs.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 9","pages":"732-738"},"PeriodicalIF":1.7,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145000958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}