Bor Hrvatin Stancic, Aleksandra Bergant Suhodolčan, Tanja Planinšek Ručigaj
{"title":"Martorell hypertensive ischaemic leg ulcer: a novel adjuvant therapy with intralesional sodium thiosulfate.","authors":"Bor Hrvatin Stancic, Aleksandra Bergant Suhodolčan, Tanja Planinšek Ručigaj","doi":"10.12968/jowc.2023.0162","DOIUrl":"https://doi.org/10.12968/jowc.2023.0162","url":null,"abstract":"<p><p>A case report of a 63-year-old female patient with long-standing diabetes and arterial hypertension with a painful progressive necrotic ulcer. She was diagnosed with Martorell hypertensive ischaemic leg ulcer (HYTILU) and multimodal therapy was initiated. This included: optimisation of therapy for the arterial hypertension and diabetes; discontinuation of her beta blocker; appropriate wound therapy; systemic antibiotic therapy; and pain management. Due to inadequate healing with the above measures, concurrent treatment with intralesional sodium thiosulfate (IL STS) was initiated for three consecutive weeks. The medication was well tolerated and resulted in complete re-epithelialisation. This is the first report of a Martorell HYTILU, successfully treated with IL STS, with no observed systemic side-effects; however, there is a need for controlled studies in a larger number of cases to prove its efficacy and safety.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 5","pages":"375-378"},"PeriodicalIF":1.5,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144017212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Safety and tolerability of kinesiotaping as add-on treatment of pressure injuries.","authors":"Paola Paglierani, Debora Donatini, Elisa Maietti, Paola Rucci, Carlotte Kiekens, Stefano Negrini, Rita Capirossi","doi":"10.12968/jowc.2023.0125","DOIUrl":"https://doi.org/10.12968/jowc.2023.0125","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to evaluate the safety and tolerability of kinesiotaping (KT) as an adjunctive treatment of medium-to-severe sacral or heel pressure injuries (PIs) in patients with spinal cord injury (SCI), and to explore the effects of tape application in promoting the healing process.</p><p><strong>Method: </strong>This pilot study was conducted in a tertiary specialised rehabilitation hospital in Italy. Patients with SCI within three months of an acute traumatic or non-traumatic event; any neurological level; complete or incomplete lesion; stage 3 or 4, sacral and/or heel PI for ≥1 month were included in the study. We used the Bates-Jensen Wound Assessment Tool (BWAT) to assess PI characteristics. PIs were treated with standard of care (SoC) for 12 weeks and KT was added after four weeks of SoC treatment for a four-week period, after which treatment reverted to SoC treatment.</p><p><strong>Results: </strong>A total of 20 patients (mean age 54 years, 75% male) with a total of 24 PIs were enrolled between September 2017 and March 2020. The PIs included: 12 sacral; 12 heel, nine stage 3; and 15 stage 4. Mean baseline BWAT score was 37.5±6.7. No adverse effects were recorded. BWAT score declined significantly (p<0.01) over 12 weeks, on average 5.3 points at four weeks, 8.9 points at eight weeks and 3.7 points at 12 weeks.</p><p><strong>Conclusion: </strong>This pilot study provides preliminary evidence of the safety and tolerability of KT. Studies have claimed that the restoration of microcirculation positively affects the healing of PIs. The findings of this study appear to demonstrate that the KT technique exploits this principle, stimulating both lymphatic and venous microcirculation. Further studies are needed to test the efficacy and effectiveness of KT on PIs versus SoC.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 5","pages":"360-367"},"PeriodicalIF":1.5,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144031828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alexandra Hj Janssen, Johannes A Wegdam, Alita Jaspar, Tammo S de Vries Reilingh, Hester Vermeulen, Anne M Eskes
{"title":"Patient preference with regard to negative pressure wound therapy and participation in wound care: a qualitative study.","authors":"Alexandra Hj Janssen, Johannes A Wegdam, Alita Jaspar, Tammo S de Vries Reilingh, Hester Vermeulen, Anne M Eskes","doi":"10.12968/jowc.2022.0145","DOIUrl":"https://doi.org/10.12968/jowc.2022.0145","url":null,"abstract":"<p><strong>Objective: </strong>To explore the experiences and preferences of patients with wounds treated with negative pressure wound therapy (NPWT) regarding shared decision-making and patient participation.</p><p><strong>Method: </strong>Semi-structured interviews were conducted with adult patients treated with NPWT. Interview topics included shared decision-making and patients' active participation in wound treatment. Thematic analysis was applied to identify themes.</p><p><strong>Results: </strong>The interview cohort comprised ten patients. Four themes emerged: (1) Having a wound makes patients uncertain and thus influences their quality of life; (2) NPWT influences patients' daily lives; (3) Patients consider professional treatment decisions most important in the decision-making processes; (4) Self-management of wounds is accepted by patients only for low-complexity and well-healing wounds under supervision. Participants emphasised their worries about the future and the impact of the wound/treatment on their families. After being thoroughly informed, participants preferred that health professionals decide on the treatment choice. In addition, participants and/or their relatives did not want to actively participate in complex wound care. As well as expressing a need for qualified wound care professionals, participants reported that they did not want to be or feel responsible for the wound treatment.</p><p><strong>Conclusion: </strong>Shared decision-making and active patient participation are underused and underexposed topics in wound care. Patients' recognition of the importance of their personal preferences can facilitate shared decision-making.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 5","pages":"340-349"},"PeriodicalIF":1.5,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144016960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Teija Kimpimäki, Maria Karhu, Annikki Vaalasti, Toni Karppinen, Harri Sintonen, Heini Huhtala, Teea Salmi, Tiina Ahti
{"title":"Health-related quality of life of patients with hard-to-heal ulcers measured with the 15D instrument: a prospective study.","authors":"Teija Kimpimäki, Maria Karhu, Annikki Vaalasti, Toni Karppinen, Harri Sintonen, Heini Huhtala, Teea Salmi, Tiina Ahti","doi":"10.12968/jowc.2022.0068","DOIUrl":"https://doi.org/10.12968/jowc.2022.0068","url":null,"abstract":"<p><strong>Objective: </strong>The aim of the study was to investigate the health-related quality of life (HRQoL) of patients with hard-to-heal ulcers in a prospective study setting, and further to investigate the factors associated with HRQoL.</p><p><strong>Method: </strong>Patients with hard-to-heal ulcers referred to the Wound Centre of Tampere University Hospital, Finland, completed the 15D HRQoL questionnaire. The 15D scores were compared to an age- and sex-matched general population cohort and to patients with chronic pain and cancer. The baseline background and clinical data of patients with hard-to-heal ulcers were obtained from patient records and the Registry of Chronic Wounds at the Wound Centre, and follow-up information via questionnaires sent to the study participants six months after the first visit. Factors associated with baseline HRQoL and HRQoL changes during the follow-up were analysed.</p><p><strong>Results: </strong>A total of 142 patients with hard-to-heal ulcers were included in the study. The mean 15D score of the patients with hard- to-heal ulcers was lower than that of the general population cohort and patients with breast and prostate cancer, but higher than that of patients with chronic pain. Patients with an arterial or mixed ulcer had the lowest 15D scores, and negative correlations were detected between 15D scores and age, number of comorbidities and use of pain medication. During follow-up, the 15D score improved significantly in 43% of the patients, but ulcer healing was not associated with increasing 15D scores.</p><p><strong>Conclusion: </strong>In this study, the HRQoL of patients with hard-to-heal ulcers was substantially impaired. In addition to ulcer aetiology, age and comorbidities were associated with HRQoL-highlighting the importance of multidisciplinary care-and this most likely explains the lack of correlation between ulcer healing and 15D score change during follow-up.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 5","pages":"350-358"},"PeriodicalIF":1.5,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143971159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Increased morbidities in pyoderma gangrenosum with extensive surgical debridement in Taiwan: a case series.","authors":"Yi-Li Hou, Chih-Hung Lee, Yu-Wen Cheng","doi":"10.12968/jowc.2022.0041","DOIUrl":"https://doi.org/10.12968/jowc.2022.0041","url":null,"abstract":"<p><strong>Objective: </strong>Delayed diagnosis and consequent extensive debridement in cases of pyoderma gangrenosum (PG) may lead to poor wound healing and unfavourable prognosis. We aimed to evaluate the epidemiological and clinical features of PG in Taiwan and investigate the clinical courses of patients who underwent extensive surgical debridement.</p><p><strong>Method: </strong>In this retrospective study, patients diagnosed with PG at a referral centre in Taiwan between 2001 and 2021 were recruited. The patients were divided into a debrided group and a non-debrided group.</p><p><strong>Results: </strong>The cohort comprised a total of 15 patients, five of whom were in the debrided group and 10 in the non-debrided group. Among all 15 patients, the average age at diagnosis was 40 years with a male preponderance (67%). PG tended to involve multiple sites (73%), the lower limbs (87%), ulcerations (80%) and had a diameter <10cm (93%). Seven patients (47%) had medical comorbidities, including inflammatory bowel disease (20%) and hypertension (20%). Ulcerative manifestations, lack of typical associated comorbidities, delayed diagnosis, prolonged lengths of hospitalisation, and high cumulative doses of systemic corticosteroids were observed in the debrided group.</p><p><strong>Conclusion: </strong>This is the first study to describe the epidemiological and clinical characteristics of PG in Taiwan in English to our knowledge. The results were mostly consistent with the existing literature, except an apparent male preponderance. Moreover, we highlight the importance of accurate diagnosis and avoidance of aggressive surgical debridement in patients with PG for both dermatologist and non-dermatologist.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 5","pages":"380-384"},"PeriodicalIF":1.5,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144029352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hypervitaminosis D and hard-to-heal wounds: a case report.","authors":"Thomas Steve Jessop, Nicolas Kairinos","doi":"10.12968/jowc.2023.0177","DOIUrl":"https://doi.org/10.12968/jowc.2023.0177","url":null,"abstract":"<p><p>Vitamin D is thought to be safe due to its wide therapeutic index and concentrations are rarely raised to toxic levels in the blood. However, excessive vitamin D supplementation can lead to hypervitaminosis D, causing hypercalcaemia and hyperphosphataemia. Due to its lipid solubility, vitamin D can be stored in adipose tissue, leading to persistent hypercalcaemia, even after supplementation has been discontinued. This case reports an 81-year-old female patient who developed hypervitaminosis D after taking excessive vitamin D supplementation for 30 years. The patient presented with complex bilateral leg wounds and tissue calcification. This case highlights the importance of monitoring vitamin D supplementation and the risks associated with hypervitaminosis D, including soft tissue calcification.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 5","pages":"368-371"},"PeriodicalIF":1.5,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144015526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Coordination in pathways of care, e-health and AI in wound healing.","authors":"Luc Téot","doi":"10.12968/jowc.2025.0154","DOIUrl":"https://doi.org/10.12968/jowc.2025.0154","url":null,"abstract":"","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 5","pages":"339"},"PeriodicalIF":1.5,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144006378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Richard Simman, Suzanne J Bakewell, Desmond Bell, Susan Shuman, Mary Cheney
{"title":"Response to: Diabetic foot ulcer treatment with a multimodal wound matrix.","authors":"Richard Simman, Suzanne J Bakewell, Desmond Bell, Susan Shuman, Mary Cheney","doi":"10.12968/jowc.2025.0163","DOIUrl":"https://doi.org/10.12968/jowc.2025.0163","url":null,"abstract":"","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 5","pages":"374"},"PeriodicalIF":1.5,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144006605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"It is time for a consensus on a definition for skin failure.","authors":"Kenneth Olshansky","doi":"10.12968/jowc.2025.0087","DOIUrl":"https://doi.org/10.12968/jowc.2025.0087","url":null,"abstract":"","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 Sup5","pages":"S3-S4"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144026812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}