Journal of wound care最新文献_第2页

Healing wounds with a multimodal botanical hydrogel: a clinical outcomes comparison study. 多模态植物水凝胶愈合伤口：临床结果比较研究。

IF 1.5 4区医学

Journal of wound care Pub Date : 2025-07-01 DOI: 10.12968/jowc.2025.0185

Sung Ho Steve Bae, Windy Cole, Imaze M Davis, Dmitry Sandler, J David Warren, Janet S Mackenzie

{"title":"Healing wounds with a multimodal botanical hydrogel: a clinical outcomes comparison study.","authors":"Sung Ho Steve Bae, Windy Cole, Imaze M Davis, Dmitry Sandler, J David Warren, Janet S Mackenzie","doi":"10.12968/jowc.2025.0185","DOIUrl":"10.12968/jowc.2025.0185","url":null,"abstract":"Objective: Diabetic foot wounds pose many challenges during the healing process and often become hard-to-heal (chronic) wounds. This study compared a novel botanical hydrogel with a widely used hydrogel to determine both its non-inferiority and impact on the progress of diabetic foot wounds.Method: The study was a prospective, double-blinded, randomised controlled study comparing healing outcomes. There were two cohorts: one treated with LAVIOR Diabetic Wound Gel (LDWG; Lavior Pharma Inc., US), which contains botanical extracts, and the other treated with SoloSite Wound Gel (SSWG) (Smith+Nephew Inc., US). The wounds were treated and evaluated weekly over a six-week period. Subjective patient data were collected with the Diabetic Foot Scale (DFS) at each visit.Results: The study cohort comprised 65 patients: 34 patients treated with LDWG, and 31 patients treated with SSWG. The patients treated with LDWG demonstrated at least as much progress in healing as those treated with SSWG. There was a greater reduction in wound surface area in the LDWG group from baseline to the end of the study (7.32cm2 to 2.24cm2) than in the SSWG group (8.18cm2 to 5.16cm2) (p=0.127). Reduction in pain was significantly improved in wounds treated with LDWG compared with SSWG (during follow-up weeks 1-4; p<0.001; week 5 was not statistically significant). The LDWG group demonstrated significantly greater improvement in DFS scores by the end of the study (scores of 192 versus 219, respectively, compared with the SSWG group; p=0.001). Wound closure times were comparable between the two groups.Conclusion: In this study, LDWG demonstrated non-inferiority to SSWG; better results were observed in pain reduction and surface area reduction. Further study is indicated.","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 Sup7","pages":"S5-S12"},"PeriodicalIF":1.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144600880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pressure injuries and sarcopenia. 压伤和肌肉减少症。

IF 1.5 4区医学

Journal of wound care Pub Date : 2025-07-01 DOI: 10.12968/jowc.2023.0275

Ayfer Durak, Umut Safer

引用次数: 0

A novel skin closure device accelerates early cosmesis in orthopaedic surgical incisions: a randomised controlled trial. 一种新型皮肤闭合装置加速骨科手术切口的早期美容：一项随机对照试验。

IF 1.5 4区医学

Journal of wound care Pub Date : 2025-07-01 DOI: 10.12968/jowc.2023.0228

Landon P Frazier, Christopher M Brusalis, Katie J McMorrow, Ryan Quigley, Joshua T Kaiser, Zachary D Meeker, Allen A Yazdi, Alexander C Weissman, Krish S Sardesai, Brian J Cole

{"title":"A novel skin closure device accelerates early cosmesis in orthopaedic surgical incisions: a randomised controlled trial.","authors":"Landon P Frazier, Christopher M Brusalis, Katie J McMorrow, Ryan Quigley, Joshua T Kaiser, Zachary D Meeker, Allen A Yazdi, Alexander C Weissman, Krish S Sardesai, Brian J Cole","doi":"10.12968/jowc.2023.0228","DOIUrl":"10.12968/jowc.2023.0228","url":null,"abstract":"Objective: Cosmesis of surgical incisions can greatly impact postoperative patient satisfaction. This study aimed to compare the rate and overall cosmetic improvement of orthopaedic surgical incisions between conventional suture closure and a novel skin closure device.Method: In this single-blind, randomised, prospective controlled trial, a consecutive series of patients undergoing orthopaedic sports medicine procedures of the knee, shoulder and elbow were randomised to undergo wound closure via either conventional suture or a micro-anchor skin closure device (BandGrip; BandGrip, US). Wounds were stratified by incision length (small ≤2cm and large >2cm). Wound cosmesis was evaluated by two blinded observers' ratings according to the Hollander Wound Evaluation Scale (HWES) at two weeks, two months and one year postoperatively. For both small and large incisions, mean HWES was compared between groups at each timepoint.Results: A total of 149 incisions were evaluated from 83 patients, including 111 incisions ≤2cm and 38 incisions >2cm. Among incisions ≤2cm, HWES ratings were significantly improved at two weeks and two months postoperatively for incisions closed with a micro-anchor skin closure device, whereas no significant differences between treatment groups were detected at one year postoperatively. Among incisions measuring >2cm (mean incision length = 7.74cm), mean HWES ratings were improved using the micro-anchor adhesive device at two months postoperatively, while HWES ratings were comparable at one year postoperatively.Conclusion: A novel micro-anchor skin closure device achieves comparable cosmetic outcomes to conventional suture and may reach satisfactory cosmesis more rapidly following orthopaedic sports medicine surgery.","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 Sup7","pages":"S23-S28"},"PeriodicalIF":1.5,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144600877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Emerging innovations in wound care: the convergence of biotechnology and AI. 伤口护理的新兴创新：生物技术和人工智能的融合。

IF 1.5 4区医学

Journal of wound care Pub Date : 2025-07-01 DOI: 10.12968/jowc.2025.0294

Amy L Couch

引用次数: 0

Best practice in the management of hidradenitis suppurativa lesions. 管理化脓性皮损的最佳实践。

IF 1.5 4区医学

Journal of wound care Pub Date : 2025-07-01 DOI: 10.12968/jowc.2025.34.Sup7b.S1

Laura Swoboda, Abigail E Chaffin, Mikael Horissian, Martha Kelso, Kimberly LeBlanc, Rachel Balow Lee, Alex G Ortega-Loayza, Julia Riley, Christopher Sayed, Joachim Dissemond, David Fitzgerald, Georgina Gethin, Alison Schofield, David Voegeli

引用次数: 0

Medical-grade honey: its definition and refined standards. 医用级蜂蜜的定义及精制标准。

IF 1.5 4区医学

Journal of wound care Pub Date : 2025-06-02 DOI: 10.12968/jowc.2024.0206

Linsey Jf Peters, Juraj Majtan, Dimitris Mossialos, Piotr Szweda, Cristina Mateescu, Ferhat Ozturk, Frank Adtg Wagener, Niels Aj Cremers

{"title":"Medical-grade honey: its definition and refined standards.","authors":"Linsey Jf Peters, Juraj Majtan, Dimitris Mossialos, Piotr Szweda, Cristina Mateescu, Ferhat Ozturk, Frank Adtg Wagener, Niels Aj Cremers","doi":"10.12968/jowc.2024.0206","DOIUrl":"https://doi.org/10.12968/jowc.2024.0206","url":null,"abstract":"The surge in the use of honey in modern medicine, driven by concerns over escalating antibiotic resistance, places an unprecedented emphasis on the need for medically safe and effective honey. In response, the term 'medical-grade honey' (MGH) emerged, accompanied by stringent criteria. However, the evolving landscape of honey authenticity challenges and new medical device regulations demand a comprehensive revision of MGH criteria and a refined definition. This article provides a clear definition of MGH and refines its standards. MGH must be: organically produced; undergo gamma sterilisation; adhere to clinical safety benchmarks; meet production standards; and meet specific physicochemical criteria, affirming its suitability for medical use. Furthermore, the authors advocate for proven biological activity in MGH, including antimicrobial and antioxidant properties, vital for medical efficacy. This paper also sheds light on significant regulatory shifts introduced by the European Union's Medical Device Regulation, enhancing device safety while demanding increased investment in terms of cost and effort. In summary, the presented refined guidelines ensure secure, effective honey use in medical contexts, reaffirming MGH's role in modern healthcare.","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 6","pages":"412-423"},"PeriodicalIF":1.5,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144275154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Think zinc in wound care. 想想伤口护理中的锌。

IF 1.5 4区医学

Journal of wound care Pub Date : 2025-06-02 DOI: 10.12968/jowc.2025.0215

Magnus S Ågren

引用次数: 0

Use of human and animal amniotic membranes in local antibiotic therapy. 人与动物羊膜在局部抗生素治疗中的应用。

IF 1.5 4区医学

Journal of wound care Pub Date : 2025-06-02 DOI: 10.12968/jowc.2022.0088

Agnieszka Klama-Baryła, Anna Sitkowska, Ewa Tomanek, Wojciech Łabuś, Wojciech Smętek, Diana Kitala, Magdalena Głogowska, Marek Kucharzewski

{"title":"Use of human and animal amniotic membranes in local antibiotic therapy.","authors":"Agnieszka Klama-Baryła, Anna Sitkowska, Ewa Tomanek, Wojciech Łabuś, Wojciech Smętek, Diana Kitala, Magdalena Głogowska, Marek Kucharzewski","doi":"10.12968/jowc.2022.0088","DOIUrl":"https://doi.org/10.12968/jowc.2022.0088","url":null,"abstract":"Objective: The antibacterial properties of amniotic membranes are the reason for their wide clinical use. Amniotic membrane soaked in antibiotics can be used in local antibiotic therapy, creating new options for the treatment of infections. The aim of this study was to analyse the inhibiting effect of both human and porcine amniotic membranes soaked in antibiotics on the growth of microorganisms.Method: Human and porcine placentas were collected during natural births, under aseptic conditions. Each amnion was divided into three parts: intravital; cryopreserved; and radio-sterilised. Discs of 8mm in diameter were cut from the amniotic membrane. The discs were incubated in antibiotics (gentamicin, neomycin sulfate and colistin) for three hours and then subjected to microbiological tests to assess the inhibition of bacterial growth. The inhibiting effect on microorganisms-Staphylococcus aureus, Pseudomonas aeruginosa, Acinetobacter baumannii, Escherichia coli, Klebsiella pneumoniae- were examined.Results: The findings of the study showed that porcine amniotic membrane was as effective in carrying antibiotics as human amnion. The ability of cryopreserved or radio-sterilised amniotic membrane to inhibit the growth of microorganisms was not reduced compared to that of fresh amnion. There was a statistically significant difference in the studied groups. The highest growth inhibition efficacy was noted for Escherichia coli, meticilin-sensitive Staphylococcus aureus, Acinetobacter baumannii-sensitive extended-spectrum beta-lactamase. The highest mean zones of growth inhibition were obtained for gentamicin and neomycin sulfate.Conclusion: This study revealed that both human and porcine amniotic membranes can be used in carrying antibiotics. Differently prepared amniotic membrane can be successfully used in microorganism inhibition.","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 6","pages":"444-454"},"PeriodicalIF":1.5,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144275234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The implementation of the 'Malignant Fungating Wound Guidelines and Pathway' and its evaluation. “恶性真菌性伤口指南和路径”的实施及其评价。

IF 1.5 4区医学

Journal of wound care Pub Date : 2025-06-02 DOI: 10.12968/jowc.2024.0182

Tracy Finley

{"title":"The implementation of the 'Malignant Fungating Wound Guidelines and Pathway' and its evaluation.","authors":"Tracy Finley","doi":"10.12968/jowc.2024.0182","DOIUrl":"https://doi.org/10.12968/jowc.2024.0182","url":null,"abstract":"Objective: There is a lack of research on malignant fungating wounds (MFWs), particularly their management and their impact on patients' quality of life. Therefore this study investigated the effectiveness of 'Malignant Fungating Wound Guidelines and Pathway' implemented in the author's NHS trust following the impact of COVID-19, an evaluation of health professionals' knowledge and, most importantly, understanding of the patient experience.Method: This quality improvement study comprised three stages. In stage 1, a literature review was conducted, which was predominately based upon online data, published articles and information gained from contacting neighbouring health trusts; this formed the guidelines and pathway. In stage 2, a pre- and a post-questionnaire were conducted, aimed at health professionals, to establish a percentage knowledge increase following the implementation of the 'Malignant Fungating Wound Guidelines and Pathway'. Stage 3 involved interviewing 10 patients and their caregivers in order to gain an insight into the lived experience with an MFW.Results: 'Malignant Fungating Wound Guidelines and Pathway' was implemented and disseminated via email to external users, such as GP practices and care homes, as well as the author's NHS trust intranet. Among the 243 health professionals contacted, 100 nurses participated in an evaluation questionnaire, the results of which demonstrated an increase in knowledge of 32%. The 10 patients who were interviewed highlighted that exudate and malodour were their main issues of concern.Conclusion: An information leaflet, aimed at patients and their caregivers, was created to draw together a shared-care approach, which will ultimately enhance outcomes for service users, including community and acute settings, in the management of patients and their caregivers.","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 6","pages":"398-410"},"PeriodicalIF":1.5,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144275232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Physiotherapy intervention in the treatment of patients with venous ulcers: a systematic literature review. 物理治疗干预治疗静脉溃疡：系统文献综述。

IF 1.5 4区医学

Journal of wound care Pub Date : 2025-06-02 DOI: 10.12968/jowc.2022.0240

Sabrina Medeiros, Rui Costa, Alexandre Rodrigues

{"title":"Physiotherapy intervention in the treatment of patients with venous ulcers: a systematic literature review.","authors":"Sabrina Medeiros, Rui Costa, Alexandre Rodrigues","doi":"10.12968/jowc.2022.0240","DOIUrl":"https://doi.org/10.12968/jowc.2022.0240","url":null,"abstract":"Objective: To identify where physiotherapy has been used as an intervention in the treatment of venous ulcers (VUs).Method: This systematic literature review was prospectively registered in the International Prospective Register of Systematic Reviews database. The search took place in March 2023 and included four electronic databases: PubMed; Cochrane Library; Web of Science; and SciELO. The review included randomised controlled trials published in the past eight years and which included subjects >18 years of age with a diagnosis of VU, and whose physiotherapy intervention was combined with a multidisciplinary wound management team. The Physiotherapy Evidence Database (PEDro) scale was used to assess the methodological quality.Results: A total of eight studies were included in the final review. Physiotherapy can treat VUs through two different modalities: therapeutic exercises and electrotherapy. Physiotherapy interventions were adjuvant to the standard treatment for wounds performed by other health professionals. The main outcomes were wound size and healing time, and obtaining favourable results within the experimental groups when compared with the control groups.Conclusion: The findings of this review demonstrated that therapeutic exercise and electrotherapy are physiotherapy modalities that, when combined with standard treatment, are an aid to the healing process of VUs.","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 6","pages":"434-442"},"PeriodicalIF":1.5,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144275155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0