{"title":"Patients with hard-to-heal wounds: a review and synthesis of their experiences and perceptions of maggot debridement.","authors":"Yu An Eng, Jie Yun Thian, Jeanette Ignacio","doi":"10.12968/jowc.2022.0223","DOIUrl":"https://doi.org/10.12968/jowc.2022.0223","url":null,"abstract":"<p><strong>Objective: </strong>There is little use of maggot debridement therapy (MDT) worldwide, albeit there is much literature supporting its benefits and effectiveness for hard-to-heal (chronic) wounds. Hard-to-heal wounds are becoming ever more prevalent and MDT can play a pivotal role in wound care management. This underuse can be associated with patients' perceptions and experiences of MDT. The aim of this study was to synthesise available evidence exploring the perceptions and experiences of patients with hard-to-heal wounds regarding MDT.</p><p><strong>Method: </strong>This was a systematic review of qualitative evidence using thematic synthesis. Published papers and grey literature from inception until December 2021 were identified from PubMed, Embase, Cochrane, CINAHL, PsycINFO, ProQuest Social Science Premium Collection, Academic Search Complete, Web of Science, WorldWideScience.org, MedNar and Scopus. The screening process, assessment of methodological quality, and data extraction were conducted by two independent reviewers. Papers included had qualitative designs, such as phenomenology and descriptive-exploratory. Mixed methods papers and case reports were included for their qualitative components. Eligible papers were appraised using checklists from the Joanna Briggs Institute for qualitative research and case reports. Data were extracted using a standardised form. Findings were synthesised using Thomas and Harden's thematic synthesis approach.</p><p><strong>Results: </strong>A total of six papers exploring patients' (n=67) perceptions and experiences regarding MDT were included. Some 52 findings were grouped into 11 categories, generating three synthesised findings: the complexity of living with a hard-to-heal wound and seeking help; the effects of interpersonal relationships; and the relationship between the individual and the larvae.</p><p><strong>Conclusion: </strong>Findings of the review showed that health professionals are key drivers in encouraging patients' acceptance of MDT and enhancing their treatment experiences. Together with a patient-centric approach, patients' concerns can be effectively addressed. Public and patient education can be beneficial to address misconceptions regarding the therapy.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 1","pages":"20-30"},"PeriodicalIF":1.5,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142965905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The provision of wound care and management in a community healthcare setting: an exploratory study.","authors":"Louise Skerritt, Martin Gooney, Linda Sheahan","doi":"10.12968/jowc.2024.0108","DOIUrl":"https://doi.org/10.12968/jowc.2024.0108","url":null,"abstract":"<p><strong>Objective: </strong>Wound management can be costly and challenging to the health services' scarce resources. Information regarding the number of wounds in a community care setting and their associated aetiology will provide nurses and nurse managers with an insight into the specific needs of these clients with wounds and highlight areas where care or services can be improved or further developed. This research aimed to establish the prevalence and aetiology of wounds, the current delivery of wound care, wound documentation and referral pathways in an Irish community care setting.</p><p><strong>Method: </strong>A retrospective chart review was carried out on all clients in the community care area who received wound care from the Public Health Nursing Service over a specified one-year period.</p><p><strong>Results: </strong>A total of 331 individuals were identified as having wounds, and nearly half presented with more than one wound, equating to 632 wounds in total (point prevalence (PP)=0.46%). A total of 56% (n=186; PP=0.14%) had leg ulcers (LUs), 18% (n=58; PP=0.04%) had pressure ulcers (PUs), 15% (n=49; PP=0.04%) had developed a diabetic foot ulcer (DFUs) and a further 11% (n=38; PP=0.03%) had wounds of other aetiologies. The mean duration of wounds was 11.37 months. Comorbidities were present in 99% (n=327) of clients with wounds, with cardiovascular disease observed in 87% (n=288) of clients and diabetes in 45% (n=148). Nursing wound-related concerns resulted in 52% (n=171) of clients receiving antibiotics, with 71% (n=121) being prescribed more than one dose. As many as 61% (n=104) of clients prescribed antibiotics did not have completed documentation to demonstrate a suspected wound infection. It was established that 16% of the Public Health Nursing Service's active caseload was made up of clients with wounds and the management of these wounds accounted for 65% of nursing time, equating to 28 full-time community nurses.</p><p><strong>Conclusion: </strong>This study has identified that people with chronic (hard-to-heal) wounds often present with more than one chronic disease, which may negatively influence the wound's healing trajectory, lengthening its duration. The criteria for onward referral for suspected wound infections have been examined and resulted in large numbers of poorly documented wound assessments, leading to a high reliance on the use of oral antibiotics as commonplace for the management of hard-to-heal wounds. Hard-to-heal wounds, such as lower LUs, PUs and DFUs, are either caused or significantly affected by the presence of underlying comorbidities. Therefore, aligning the prevention and management of these burdensome wounds with National Clinical Programmes will deliver efficient, cost-effective, holistic quality care to clients in Irish community healthcare settings.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 1","pages":"74-87"},"PeriodicalIF":1.5,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142964696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Updated Local Coverage Determinations: their impact on wound care.","authors":"William H Tettelbach","doi":"10.12968/jowc.2024.0435","DOIUrl":"https://doi.org/10.12968/jowc.2024.0435","url":null,"abstract":"","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 1","pages":"89"},"PeriodicalIF":1.5,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142965283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Li Chen, Xiaojun Wang, Haijiao Wang, Yanhui Tang, Man Luo, Ming Chen
{"title":"Wound care of Sweet syndrome in a patient with anaplastic lymphoma kinase-positive anaplastic large cell lymphoma: a case report.","authors":"Li Chen, Xiaojun Wang, Haijiao Wang, Yanhui Tang, Man Luo, Ming Chen","doi":"10.12968/jowc.2023.0223","DOIUrl":"https://doi.org/10.12968/jowc.2023.0223","url":null,"abstract":"<p><p>Sweet syndrome (SS), which is characterised by fever and erythematous tender skin lesions, has been shown to be associated with lymphoma. However, there are limited reported experiences on the wound care of SS in patients with lymphoma. This case report presents the wound care of SS in a patient with anaplastic lymphoma kinase (ALK)-positive anaplastic large cell lymphoma (ALK+ALCL). A 42-year-old male was referred to the The First Affiliated Hospital of Guangzhou University of Chinese Medicine Hospital with redness and pain in the left shoulder and abdomen following chemotherapy for ALK+ALCL in early 2021. Physical examination found lesions in the abdomen and shoulder. The lesions were ruptured on day 5 and found to be composed of necrotic tissues. After debridement, the wounds were successively treated with silver ion antibacterial dressing, Mepilex Border Lite (Mölnlycke Health Care, Sweden), silver sulfadiazine gauze, Shengji ointment (a traditional Chinese therapy), UrgoTül (Urgo Medical, France), and fire needling therapy (another traditional Chinese therapy). At three months later, the wound in the abdomen was healed, but the shoulder wound was still unhealed. Based on the physiological manifestations and current treatment process, the patient was diagnosed with SS after multidisciplinary consultation. Prednisone tablets were then administered and the shoulder wound completely healed after two months.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 1","pages":"5-8"},"PeriodicalIF":1.5,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142965205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of wound carePub Date : 2024-12-02Epub Date: 2024-11-23DOI: 10.12968/jowc.2024.0174
Naz Wahab, William H Tettelbach, Vickie Driver, Martha R Kelso, Julie L De Jong, Brandon Hubbs, R Allyn Forsyth, Alisha Oropallo
{"title":"The impact of dual-enrolee (Medicare/Medicaid) status on venous leg ulcer outcomes: a retrospective study.","authors":"Naz Wahab, William H Tettelbach, Vickie Driver, Martha R Kelso, Julie L De Jong, Brandon Hubbs, R Allyn Forsyth, Alisha Oropallo","doi":"10.12968/jowc.2024.0174","DOIUrl":"https://doi.org/10.12968/jowc.2024.0174","url":null,"abstract":"<p><strong>Objective: </strong>To quantify race, sex, comorbidities, Medicaid status, and compare health outcomes for Medicare-only versus Medicare/Medicaid dual-enrolees who developed a hard-to-heal venous leg ulcer (VLU).</p><p><strong>Method: </strong>Medicare Limited Data Standard analytic hospital inpatient and outpatient department files were used to follow episodes of medical care for a VLU from 1 October 2015-2 October 2019. In an earlier study, patients diagnosed concurrently with chronic venous insufficiency and a VLU were propensity-matched. In this current work, cohorts were split into patients enrolled in Medicare-only and those enrolled in Medicare and Medicaid (dual-enrolees). Treatment methods were compared and the most commonly used cellular, acellular and matrix-like product (CAMP) among Medicare beneficiaries-dehydrated human amnion chorion membrane (DHACM)-was evaluated. Episode claims were used to document demographics, comorbidities and treatments of Medicare enrolees who developed VLUs and outcomes such as time to ulcer closure, rates of complications and hospital usage rates. Quality of life (QoL) metrics, such as pain and time to VLU closure, were compared across the groups.</p><p><strong>Results: </strong>Of the 555,284 Medicare beneficiaries evaluated in this analysis, 27% were Medicare/Medicaid dual-enrolees and 73% were Medicare-only enrolees. To qualify for Medicaid, patient income had to be ≤133% of the federal poverty level. Only 3% of Medicare-only patients and 6% of dual-enrolees had an Advantage plan, a lower rate than the general Medicare population. Dual-enrolees, compared to those covered by Medicare-only, demonstrated: a Charlson Comorbidity Index (CCI) score one point greater (p<0.0001); a higher percentage (16%) of patients from minority ethnic backgrounds; and significantly higher rates of emergency department visits (p<0.0001) and cellulitis (p=0.034). Dual-enrolees who received early and regularly applied CAMPs also reduced their treatment time by 21 days (p=0.0027), all of which can impact costs.</p><p><strong>Conclusion: </strong>The socioeconomic status of dual-enrolees included near poverty status, a higher percentage of patients from a minority ethnic background, and high rates of comorbidities compared to their Medicare-only counterparts. The VLUs of dual-enrolees took longer to close, developed more complications, and used significantly more hospital resources and expenses. Outcomes significantly improved when VLU episodes were treated with a CAMP, such as DHACM, while following parameters for use. Socioeconomic variables are associated with poor outcomes for patients with hard-to-heal (chronic) wounds. This should be tracked to find cost-effective interventions throughout their journey to provide equitable care and ensure they are not left behind. Greater access for dual-enrolees to CAMPs has the potential to improve clinical outcomes and patient QoL, while concomitantly reducing overall healthc","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"33 12","pages":"886-892"},"PeriodicalIF":1.5,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142780412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Wounds in a correctional facility in Malta: a point prevalence study.","authors":"Anthea Gabriele, Samantha Holloway, Corinne Scicluna Ward","doi":"10.12968/jowc.2023.0220","DOIUrl":"https://doi.org/10.12968/jowc.2023.0220","url":null,"abstract":"<p><p>Hard-to-heal (chronic) wounds are a challenge to wound care professionals, a burden to the health service and negatively impact affected individuals' quality of life. They also consume a great deal of healthcare resources globally and are found in all settings, including prisons. Therefore, the evaluation of wound care services is essential in order to develop an awareness of where improvement can be made. The main aim of this point prevalence study was to gather data on wounds, wound aetiology and wound management in a Maltese correctional facility. A secondary aim was to compare current practice with the best evidence-based practice and clinical practice guidelines, in order to provide a set of recommendations which can be implemented to improve the service. A retrospective study was carried out, auditing the medical records of people with justice involvement. The results of the audit reported a low prevalence of wounds. While practice met existing standards, for example, no unnecessary wound swab was taken, several shortcomings in wound management were noted. To improve adherence to the clinical guidelines in conjunction with improving the quality of the current service offered in the wound clinic, a number of short- and long-term clinical recommendations were proposed including: the incorporation of pain assessment tools and C-reactive protein blood testing for identifying infection; early referral to specialised care for individuals with diabetic foot ulcers, as well as the necessity for proficient personnel specialising in wound management training.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"33 12","pages":"934-940"},"PeriodicalIF":1.5,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142780422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Coeway Boulder Thng, Keng Lin Wong, Allen Wei-Jiat Wong, Khong Yik Chew, Kimberley Leow, Leon Timothy Charles Alvis, Sum Leong, Farah Gillan Irani, Wenxian Png, Eric Wei Liang Cher, Zhongzheng Ma, Mardiana Binte Moksin, Merng Koon Wong, Pearlie Woon Woon Tan, Yee Onn Kok, Jiajun Feng
{"title":"Early results of an orthoplastic multidisciplinary approach to diabetic foot ulcer soft tissue reconstruction.","authors":"Coeway Boulder Thng, Keng Lin Wong, Allen Wei-Jiat Wong, Khong Yik Chew, Kimberley Leow, Leon Timothy Charles Alvis, Sum Leong, Farah Gillan Irani, Wenxian Png, Eric Wei Liang Cher, Zhongzheng Ma, Mardiana Binte Moksin, Merng Koon Wong, Pearlie Woon Woon Tan, Yee Onn Kok, Jiajun Feng","doi":"10.12968/jowc.2023.0008","DOIUrl":"https://doi.org/10.12968/jowc.2023.0008","url":null,"abstract":"<p><strong>Objective: </strong>Diabetic foot ulcer (DFU) is a common complication in patients with diabetes. With current treatment, only two-thirds of patients heal, with a median duration of 3-6 months. Hard-to-heal DFUs are a major source of morbidity and mortality. Improving wound healing via soft tissue reconstruction may be the key to improving clinical outcomes. Thus, the Diabetic Limb Salvage (DLS) service in Sengkang General Hospital, Singapore, was established to provide patients with a streamlined, one-stop, comprehensive service dedicated to DFU soft tissue reconstruction. The reconstruction was carried out using secondary closure, skin grafting, local flaps or free flaps, depending on the severity of the wound and patient suitability. This study aims to audit the early outcomes of the DLS service.</p><p><strong>Method: </strong>Patients with DFUs treated by the DLS service were compared with patients with DFUs treated prior to the launch of the DLS service (control). Outcomes including major and minor amputation rates, wound healing rate, mortality and DFU recurrence rates were analysed statistically.</p><p><strong>Results: </strong>A total of 103 patients took part in the study (50 in the DLS service cohort and 50 in the control cohort). There was no significant difference in demographics, comorbidities and wound profiles between the two cohorts. All (100%) patients in the DLS service cohort received soft tissue reconstruction versus only 13% in the control group. The DLS service cohort had a significantly higher healing rate (96% versus 68%, respectively), shorter healing duration (77±30 days versus 111±43 days, respectively), reduced major amputation rate (0% versus 9%, respectively), and reduced recurrence rate (6% versus 25%, respectively) compared with the control cohort within the one-year follow-up.</p><p><strong>Conclusion: </strong>The findings of this study showed that an orthoplastic multidisciplinary approach focused on DFU soft tissue reconstruction improved wound healing rates, shortened healing duration and, as a result, lowered amputation rates and reduced recurrence.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"33 12","pages":"926-932"},"PeriodicalIF":1.5,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142780607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Use of a bioactive matrix glove in the treatment of paediatric hand burns: a case series.","authors":"Olivia Julian, Slava Agafonoff, Paul M Glat","doi":"10.12968/jowc.2022.0199","DOIUrl":"10.12968/jowc.2022.0199","url":null,"abstract":"<p><strong>Objective: </strong>Burns to the hand are a common injury in paediatrics and can be traumatic to children, both physically and psychologically. Timely conservative or operative management is critical to maximise healing and minimise long-term complications in these young patients. Here, we present the cases of patients treated with a novel skin substitute formed into a prefabricated glove. The glove (PermeaDerm, Inc., US) is a bioactive matrix composed of a silicone composite membrane embedded with collagen and aloe extract with variable porosity that allows moisture to pass to a secondary dressing. To our knowledge, our group was the first to treat a small set of paediatric patients with hand burns with the glove.</p><p><strong>Method: </strong>A chart review was conducted to analyse hospital course, treatment length, complications and outcomes for each patient.</p><p><strong>Results: </strong>The age range of the five patients included in this case series was seven months to three years. All five patients had scald burns to the hand. Overall, healing with the glove was successful, with little scarring or altered skin pigmentation, and a full range of motion at the affected joints.</p><p><strong>Conclusion: </strong>Hand burns in paediatric patients are traumatic and cumbersome to the patient and their families. This bioactive matrix glove allows for a one-time application, decreases operating room time and need, and reduces the demand for multiple dressing changes. In our set of five patients, the glove showed promising results as a safe and effective noninvasive treatment option for hand burns in paediatric patients.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"33 12","pages":"893-897"},"PeriodicalIF":1.5,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142780419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Speaker profile and interview: Thomas Serena.","authors":"Thomas E Serena","doi":"10.12968/jowc.2024.0412","DOIUrl":"https://doi.org/10.12968/jowc.2024.0412","url":null,"abstract":"","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"33 12","pages":"974-975"},"PeriodicalIF":1.5,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142780401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Adjunctive hyperbaric oxygen therapy and negative pressure wound therapy for hard-to-heal wounds: a systematic review and meta-analysis.","authors":"Liehao Yang, Jiao Kong, Yunlong Xing, Lingfeng Pan, Caihong Li, Zhuoxia Wu, Mingxi Li, Lianbo Zhang","doi":"10.12968/jowc.2022.0213","DOIUrl":"10.12968/jowc.2022.0213","url":null,"abstract":"<p><strong>Objective: </strong>Negative pressure wound therapy (NPWT) and hyperbaric oxygen therapy (HBOT) have been widely used in the treatment of hard-to-heal (chronic) wounds, but there is still a lack of sufficient evidence for their combined use for the treatment of hard-to-heal wounds. This systematic review aimed to identify the clinical efficacy and safety of adding adjunctive HBOT to NPWT for hard-to-heal wounds.</p><p><strong>Method: </strong>Embase, PubMed, Cochrane Library, Web of Science, China National Knowledge Infrastructure and Wanfang were searched from the establishment of the database to March 2022. The literature was screened according to the inclusion criteria and exclusion criteria. We assessed the quality of each included study with the Cochrane Collaboration Risk of Bias tool and Newcastle-Ottawa Scale. A meta-analysis was performed using R programming software version 4.1.0 (R Project for Statistical Computing, US). The PRISMA 2020 guidelines were used to report data from systematic reviews and meta-analysis.</p><p><strong>Results: </strong>A total of 15 studies were identified, including nine randomised clinical controlled trials and six retrospective studies. Meta-analysis results showed that NPWT combined with HBOT had better outcomes compared with the NPWT alone with regards to: wound healing rate (odds ratio (OR)=6.77; 95% confidence interval (Cl): 3.53-12.98; p<0.0001); bacterial positive rate of wound (OR=0.16; 95% CI: 0.05-0.55; p=0.0037); wound healing time (mean difference (MD)= -3.86; 95% Cl: -5.18 - -2.53; p<0.0001); wound area (standardised mean difference (SMD)=1.50; 95% Cl: 0.35-2.65; p=0.0104); hospitalisation time (MD= -3.14; 95% Cl: -4.93 - -1.36; p=0.005); and hospitalisation cost (OR= -202.64; 95% Cl: -404.53 - -0.75; p=0.0492). There was no significant difference in pain score (MD= -0.43; 95% Cl: -1.15-0.30; p=0.25).</p><p><strong>Conclusion: </strong>The findings of this study demonstrated that adjunctive HBOT with NPWT is safe and effective in the treatment of hard-to-heal wounds. However, these findings should be interpreted with great caution given the limitations of the studies included.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"33 12","pages":"950-957"},"PeriodicalIF":1.5,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142780603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}