Journal of wound care最新文献

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Relationship between cleaning frequency and pressure ulcer healing time in older people receiving home care. 接受家庭护理的老年人的清洁频率与压疮愈合时间之间的关系。
IF 1.9 4区 医学
Journal of wound care Pub Date : 2024-06-02 DOI: 10.12968/jowc.2021.0152
Yoshiyuki Yoshikawa, Noriaki Maeshige, Masayuki Tanaka, Mikiko Uemura, Terutaka Hiramatsu, Hidemi Fujino, Masaharu Sugimoto, Hiroto Terashi
{"title":"Relationship between cleaning frequency and pressure ulcer healing time in older people receiving home care.","authors":"Yoshiyuki Yoshikawa, Noriaki Maeshige, Masayuki Tanaka, Mikiko Uemura, Terutaka Hiramatsu, Hidemi Fujino, Masaharu Sugimoto, Hiroto Terashi","doi":"10.12968/jowc.2021.0152","DOIUrl":"https://doi.org/10.12968/jowc.2021.0152","url":null,"abstract":"<p><strong>Objective: </strong>The relationship between the healing time of pressure ulcers (PUs) and wound cleaning frequency among older people in homecare settings was investigated.</p><p><strong>Method: </strong>This single-centre, prospective cohort study was conducted from April 2018 to March 2019. Patients who used home-visit nursing services, had National Pressure Ulcer Advisory Panel classification stage 2 PUs, and had their wounds cleaned at least twice a week were enrolled in the study. Wound cleaning was performed using tap water and a weakly acidic cleanser. Participants were divided into two groups, determined by the frequency of wound cleaning (twice weekly versus ≥3 times weekly). Duration of PU healing and the increase in care insurance premiums were compared in both groups.</p><p><strong>Results: </strong>A total of 12 patients were included in the study. The mean healing period of PUs cleaned ≥3 times per week (65.3±24.8 days) was significantly shorter than that of PUs cleaned twice a week (102.6±19.2 days; p<0.05). Furthermore, the increase in care insurance premiums for PUs cleaned ≥3 times per week (¥122,497±105,660 Yen per six months) was significantly lower than that for PUs cleaned twice a week (¥238,116±60,428 per six months) (p<0.05).</p><p><strong>Conclusion: </strong>Our results suggest that frequent cleaning of PUs by health professionals in homecare settings not only shorten PU healing period but also reduces care insurance premiums for PU care.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"33 6","pages":"418-424"},"PeriodicalIF":1.9,"publicationDate":"2024-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141284061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pressure ulcers related to prone positioning: a pandemic amidst a pandemic. 与俯卧位有关的压疮:大流行中的大流行。
IF 1.5 4区 医学
Journal of wound care Pub Date : 2024-06-02 DOI: 10.12968/jowc.2021.0105
Hassiel Aurelio Ramirez-Marin, Irazu Contreras-Yañez, Karin Ivette Campos-Jimenez, Leticia Molina-Murrieta, Yeni Huerta-Ramirez, Judith Guadalupe Domínguez-Cherit
{"title":"Pressure ulcers related to prone positioning: a pandemic amidst a pandemic.","authors":"Hassiel Aurelio Ramirez-Marin, Irazu Contreras-Yañez, Karin Ivette Campos-Jimenez, Leticia Molina-Murrieta, Yeni Huerta-Ramirez, Judith Guadalupe Domínguez-Cherit","doi":"10.12968/jowc.2021.0105","DOIUrl":"10.12968/jowc.2021.0105","url":null,"abstract":"<p><strong>Objective: </strong>To explore the epidemiology and risk factors associated with the development of pressure ulcers (PUs) in patients receiving prone positioning (PP) ventilatory therapy; to compare the inflammatory status of patients who develop PUs with those who do not; and to describe the experience and useful findings that have allowed us to improve the management of these patients to reduce the incidence of PUs.</p><p><strong>Method: </strong>An observational, descriptive and longitudinal study was conducted, where sociodemographic and laboratory data were collected from patients who were hospitalised and required PP ventilatory therapy in critical care areas (CCA) during the months of May-October 2020.</p><p><strong>Results: </strong>From the total number of patients who required PP during their CCA stay (n=240), 202 (84.2%) developed a PU. The four most frequent areas where a PU appeared were: the head and neck (n=115); the pinna (n=21); the torso (n=21); and the lower limbs (n=21). Patients who developed PU were more frequently males with higher initial levels of creatinine phosphokinase and ferritin. The incidence for each month of follow-up decreased from 8.3% to 5.8%.</p><p><strong>Conclusion: </strong>Regardless of the intervention, a multidisciplinary approach is required to optimise the prevention and treatment of these wounds. While PUs are often the result of other medical conditions or poor health status in general, the vast majority of PUs are avoidable.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"33 6","pages":"451-460"},"PeriodicalIF":1.5,"publicationDate":"2024-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141284060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Best practice for wound debridement. 伤口清创的最佳做法。
IF 1.5 4区 医学
Journal of wound care Pub Date : 2024-06-01 DOI: 10.12968/jowc.2024.33.Sup6b.S1
Dieter O Mayer, William H Tettelbach, Guido Ciprandi, Fiona Downie, Jane Hampton, Heather Hodgson, Jose Luis Lazaro-Martinez, Astrid Probst, Greg Schultz, Ewa Klara Stürmer, Alison Parnham, Nicoletta Frescos, Duncan Stang, Samantha Holloway, Steve L Percival
{"title":"Best practice for wound debridement.","authors":"Dieter O Mayer, William H Tettelbach, Guido Ciprandi, Fiona Downie, Jane Hampton, Heather Hodgson, Jose Luis Lazaro-Martinez, Astrid Probst, Greg Schultz, Ewa Klara Stürmer, Alison Parnham, Nicoletta Frescos, Duncan Stang, Samantha Holloway, Steve L Percival","doi":"10.12968/jowc.2024.33.Sup6b.S1","DOIUrl":"10.12968/jowc.2024.33.Sup6b.S1","url":null,"abstract":"","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"33 Sup6b","pages":"S1-S32"},"PeriodicalIF":1.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141199422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Non-lactational mastitis with multiple sinus wounds treated by integrated traditional Chinese and Western medicine. 中西医结合治疗非哺乳期乳腺炎伴多发性窦道伤口。
IF 1.9 4区 医学
Journal of wound care Pub Date : 2024-06-01 DOI: 10.12968/jowc.2022.0050
Yinhua Zhang, Ranran Zhang, Chunlei Sun, Dong Meng, Ling Chen
{"title":"Non-lactational mastitis with multiple sinus wounds treated by integrated traditional Chinese and Western medicine.","authors":"Yinhua Zhang, Ranran Zhang, Chunlei Sun, Dong Meng, Ling Chen","doi":"10.12968/jowc.2022.0050","DOIUrl":"10.12968/jowc.2022.0050","url":null,"abstract":"<p><strong>Objective: </strong>Non-lactational mastitis (NLM) is a benign inflammatory disease of the mammary gland, with pain, swelling and redness as the main clinical manifestations. There is no unified and effective standard treatment plan for this disease at present. In addition to breast cancer, non-lactational mastitis is also becoming a presenting complaint in an increasing number of outpatients at the authors' clinic. This case report summarises the treatment and management of a 35-year-old female patient with NLM complicated with multiple sinus wounds after surgery.</p><p><strong>Method: </strong>The patient was treated as follows, with: timely debridement according to the local condition of the wound, with manual compression to drain exudate from the sinus wound; selected wound dressings according to their performance and characteristics to fill the sinus tract for drainage and infection control; psychological care of the patient and their family to ensure that patients actively participate in the treatment; family support to the patient to deal with negative emotions; integrated traditional Chinese and Western medicine to prevent/manage infection; dietary care and control; posture management and health education to facilitate the patient's wound healing process.</p><p><strong>Results: </strong>After local management with systemic treatment and management using integrated traditional Chinese and Western medicine, the wound healed after 46 days, with no recurrence during a follow-up period of one year.</p><p><strong>Conclusion: </strong>As shown in this case report, the wound should be cut and drained as soon as possible in order to prevent obstruction of the sinus drainage. Modern wound dressings are selected for the 'external' treatment of local wounds. Integrated traditional Chinese and Western medicine may help in systemic therapy of the whole patient.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"33 Sup6","pages":"S4-S7"},"PeriodicalIF":1.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141284066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lessons learnt from an aggressive tumour masquerading as a neuropathic heel ulcer: a case report. 从伪装成神经性足跟溃疡的侵袭性肿瘤中汲取的教训:病例报告。
IF 1.9 4区 医学
Journal of wound care Pub Date : 2024-06-01 DOI: 10.12968/jowc.2022.0281
Qusai AlJarrah, Arafat M Hammad, Bana Eyad Shehadeh, Mohammad AlQudah, Ahmad K Abou-Foul
{"title":"Lessons learnt from an aggressive tumour masquerading as a neuropathic heel ulcer: a case report.","authors":"Qusai AlJarrah, Arafat M Hammad, Bana Eyad Shehadeh, Mohammad AlQudah, Ahmad K Abou-Foul","doi":"10.12968/jowc.2022.0281","DOIUrl":"10.12968/jowc.2022.0281","url":null,"abstract":"<p><p>Cutaneous malignant melanoma (cMM) can develop at any site, but one-third of cases primarily affect the lower extremities, with ankle and foot lesions representing 3-15% of all cases. However, cMM may become a clinical conundrum when it presents as chronic ulceration that is clinically indiscernible from other lower extremity ulcers in patients with diabetes. We present the case of a 71-year-old female patient with a longstanding history of diabetes, hypertension, obesity, chronic kidney disease and heart failure who presented to our hospital with a fungating heel ulcer. The lesion was initially managed in another hospital as a neuropathic diabetic foot ulcer (DFU), treated by multiple local wound debridement. However, the ulcer progressed into a fungating heel lesion that interfered with the patient's mobility and quality of life. Consequently, the patient was referred to our specialist diabetic foot service for further management. Excisional biopsy of the lesion disclosed a cMM. Positron emission tomography/computed-tomography scanning revealed hypermetabolic ipsilateral inguinal lymphadenopathy, and a right cerebral metastasis for which palliative chemotherapy was initiated. Immunotherapy was considered, but the patient died before it was started. Atypical foot ulcers in patients with diabetes warrant a careful diagnostic approach, especially for recalcitrant cutaneous lesions not responding to standard therapies. Conscientious management, without undue delay in obtaining a histopathological diagnosis, might lead to early diagnosis of melanoma and potentially more favourable outcomes. This case highlights the importance of consideration of atypical foot lesions, in general practice in addition to referral centres, to try to identify alarming features and act accordingly.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"33 Sup6","pages":"S20-S24"},"PeriodicalIF":1.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141284065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The WUWHS commitment to sharing best practice. WUWHS 致力于分享最佳实践。
IF 1.5 4区 医学
Journal of wound care Pub Date : 2024-06-01 DOI: 10.12968/jowc.2024.0161
Harikrishna Kr Nair
{"title":"The WUWHS commitment to sharing best practice.","authors":"Harikrishna Kr Nair","doi":"10.12968/jowc.2024.0161","DOIUrl":"10.12968/jowc.2024.0161","url":null,"abstract":"","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"33 Sup6","pages":"S3"},"PeriodicalIF":1.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141284068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical use of 0.1% polyhexanide and propylbetaine on acute and hard-to-heal wounds: a literature review. 0.1% 聚己内酯和丙基甜菜碱在急性和难愈合伤口上的临床应用:文献综述。
IF 1.9 4区 医学
Journal of wound care Pub Date : 2024-06-01 DOI: 10.12968/jowc.2019.0066
Giuseppe Lazzari, Simonetta Cesa, Emilia Lo Palo
{"title":"Clinical use of 0.1% polyhexanide and propylbetaine on acute and hard-to-heal wounds: a literature review.","authors":"Giuseppe Lazzari, Simonetta Cesa, Emilia Lo Palo","doi":"10.12968/jowc.2019.0066","DOIUrl":"10.12968/jowc.2019.0066","url":null,"abstract":"<p><strong>Objective: </strong>To summarise the findings on the effect of the clinical use of 0.1% polyhexanide-propylbetaine (PHMB/betaine) solution/gel on acute and hard-to-heal (chronic) wound healing.</p><p><strong>Method: </strong>A literature search was conducted in MEDLINE, CINAHL, Embase, Scopus and the CENTRAL Trials Registry of the Cochrane Collaboration. Paired reviewers conducted title and abstract screening and full-text screening to identify experimental, quasi-experimental and observational studies. Study quality and risk of bias were not formally evaluated.</p><p><strong>Results: </strong>A total of 17 studies met the eligibility criteria. The findings from 12 studies indicated that the use of 0.1% PHMB/betaine solution/gel had: a low risk of contact sensitivity; could help debridement during wound cleansing; aided effective wound bed preparation; reduced wound size, odour and exudate; improved pain control; reduced microbial load; and enhanced wound healing. The results of three studies indicated that both 0.1% PHMB and saline solution were effective in reducing bacterial load, while another showed that adding 0.1% PHMB to tie-over dressings had no effect on reducing bacterial loads in wounds. Another study concluded that disinfection and granulation of pressure ulcers with hydrobalance dressing with 0.3% PHMB was faster and more effective than using 0.1% PHMB/betaine.</p><p><strong>Conclusion: </strong>The findings of this literature review showed that 0.1% PHMB/betaine solution/gel appeared to be useful and safe for wound cleansing, was effective in removing soft debris and slough from the wound bed, and created a wound environment optimal for healing. Although these actions cannot be attributed solely to this treatment modality, these results do highlight the unique action of this combined product. However, more robust studies are needed to confirm these results.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"33 Sup6a","pages":"cxl-cli"},"PeriodicalIF":1.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141293478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correlation between initial serum 25-hydroxyvitamin D and granulation growth in diabetic foot ulcers. 糖尿病足溃疡中初始血清 25- 羟维生素 D 与肉芽生长之间的相关性。
IF 1.9 4区 医学
Journal of wound care Pub Date : 2024-06-01 DOI: 10.12968/jowc.2021.0243
Em Yunir, Fajar Englando Alan Adesta, Aulia Rizka, Tri Juli Edi Tarigan
{"title":"Correlation between initial serum 25-hydroxyvitamin D and granulation growth in diabetic foot ulcers.","authors":"Em Yunir, Fajar Englando Alan Adesta, Aulia Rizka, Tri Juli Edi Tarigan","doi":"10.12968/jowc.2021.0243","DOIUrl":"https://doi.org/10.12968/jowc.2021.0243","url":null,"abstract":"<p><strong>Objective: </strong>To determine the correlation between initial serum 25-hydroxyvitamin D (25(OH)D) levels with granulation growth in diabetic foot ulcers (DFUs) after 21 days of treatment.</p><p><strong>Method: </strong>This cohort study involved patients with type 2 diabetes who had a DFU treated at hospital. Blood samples were taken from patients on admission. The chemiluminescent immunoassay technique was used to measure 25(OH)D levels. Granulation tissue growth was analysed by comparing the photographs from the initial treatment to day 21 of treatment.</p><p><strong>Results: </strong>The median value of 25(OH)D levels at initial treatment was 8 ng/ml. The result showed no correlation between 25(OH)D levels and the granulation growth in DFUs (p=0.86).</p><p><strong>Conclusion: </strong>The initial serum 25(OH)D level was not correlated with the growth of granulation tissue in DFUs.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"33 Sup6a","pages":"clii-clix"},"PeriodicalIF":1.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141293479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predictors of surgical management in diabetic foot infections. 糖尿病足感染手术治疗的预测因素。
IF 1.9 4区 医学
Journal of wound care Pub Date : 2024-06-01 DOI: 10.12968/jowc.2021.0010
Tuna Demirdal, Pinar Sen
{"title":"Predictors of surgical management in diabetic foot infections.","authors":"Tuna Demirdal, Pinar Sen","doi":"10.12968/jowc.2021.0010","DOIUrl":"https://doi.org/10.12968/jowc.2021.0010","url":null,"abstract":"<p><strong>Objective: </strong>Early recognition of the need for surgical intervention is crucial in terms of limiting amputation level and decreasing mortality. We aimed to determine the risk factors for limb loss in patients with diabetic foot infection (DFI).</p><p><strong>Method: </strong>Data of hospitalised patients with a DFI between 2010 and 2019 were collected retrospectively from their hospital records. Clinical and laboratory findings were analysed according to the type of treatment.</p><p><strong>Results: </strong>Data were collected for 401 patients, 280 (69.8%) of whom were male. The mean age was 59.6±11.1 years. Treatment modalities included: medical treatment (36.4%); debridement/drainage (21.9%); minor amputation (17.7%); and major amputation (23.9%). Forefoot infection (odds ratio (OR): 3.347; 95% confidence interval (Cl): 1.408-7.956) and peripheral arterial disease (OR: 4.990; 95% Cl: 1.225-20.324) were found to be significant in predicting limb loss, while duration of diabetes (≥20 years) and absence of forefoot infection were significant predictors of debridement/drainage. Subgroup analysis showed that high leukocyte levels (>16.4K/μl) and forefoot infections were independent predictors for major and minor amputation, respectively.</p><p><strong>Conclusion: </strong>The clinical parameters used in this study are simple, broadly available, cost-effective and promising for predicting limb loss in patients with DFI.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"33 Sup6a","pages":"clx-clxx"},"PeriodicalIF":1.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141293480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Piperacillin/tazobactam-induced sudden severe thrombocytopenia in a patient with a pressure ulcer: a case report. 哌拉西林/他唑巴坦诱发一名压疮患者突发严重血小板减少症:病例报告。
IF 1.9 4区 医学
Journal of wound care Pub Date : 2024-06-01 DOI: 10.12968/jowc.2021.0074
Solji Roh, Kohei Hashimoto, Rina Kiriishi, Ken Matsubara, Yuki Isozaki, Hiroaki Tanaka, Tomoyuki Kuwata
{"title":"Piperacillin/tazobactam-induced sudden severe thrombocytopenia in a patient with a pressure ulcer: a case report.","authors":"Solji Roh, Kohei Hashimoto, Rina Kiriishi, Ken Matsubara, Yuki Isozaki, Hiroaki Tanaka, Tomoyuki Kuwata","doi":"10.12968/jowc.2021.0074","DOIUrl":"10.12968/jowc.2021.0074","url":null,"abstract":"<p><p>The standard treatment for an infected pressure ulcer (PU) with osteomyelitis is debridement, wound coverage and antibiotic administration. However, systemic administration of antibiotics in patients with osteomyelitis is controversial, and the optimal treatment duration for chronic osteomyelitis has not been standardised. We report a case of sudden severe thrombocytopenia induced by piperacillin/tazobactam (PIPC/TAZ) in a patient with PU-related osteomyelitis. A 57-year-old male patient with paraplegia, using a wheelchair full-time, presented to our plastic surgery department with infection of a stage IV hard-to-heal ischial PU. We surgically debrided the necrotising tissue and raised an ipsilateral biceps femoris musculocutaneous propeller flap for wound coverage. Polymicrobial infections, including <i>Pseudomonas aeruginosa</i>, were detected in the bone biopsy sample; therefore, systemic PIPC/TAZ was administered for the osteomyelitis. Unexpectedly, during the next 12 days of antibiotic administration, the patient's platelet count acutely dropped to 1×10<sup>3</sup>/μl over three days. Based on a series of examinations, PIPC/TAZ was suspected to be the most likely cause of the severe thrombocytopenia. After drug discontinuation, the thrombocytopenia gradually improved. PIPC/TAZ is one of the most widely used antibiotic combinations in the plastic surgery field; it is conventionally administered for hard-to-heal wounds such as PUs and diabetic foot. The present case suggests that surgeons must take special precautions for patients undergoing PIPC/TAZ treatment. In this report, PIPC/TAZ-induced thrombocytopenia and the efficacy of antibiotic treatment for PU-related osteomyelitis are discussed in light of the available literature.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"33 Sup6","pages":"S25-S30"},"PeriodicalIF":1.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141284067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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