Journal of wound care最新文献

{"title":"A clinical investigation of a new gelling fibre dressing containing silver for the management of venous leg ulcers.","authors":"John McRobert, Malene Høj Outzen, Charlotte Hindsberger, Kristine Gjødsbøl, Johanne Louise Gotfredsen, Debera Drew","doi":"10.12968/jowc.2025.0486","DOIUrl":"10.12968/jowc.2025.0486","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the performance and safety of Biatain Fiber Ag (Coloplast A/S, Denmark), a new gelling fibre wound dressing containing silver, in venous leg ulcers (VLUs) after four weeks of treatment.</p><p><strong>Method: </strong>This non-comparative, one-armed, open-labelled study included patients from two sites (clinics or community nursing caseloads) in the UK between February and May 2024. The primary endpoint was relative wound area reduction (WAR) after four weeks of treatment. Adverse events (AEs) were also assessed.</p><p><strong>Results: </strong>In total, 50 patients with VLUs either infected or at risk of infection, and with medium-to-high levels of exudate, were included in the intention-to-treat (ITT) population. Of these, 45 patients completed the investigation on treatment and five patients discontinued the treatment. In the primary analysis, the estimated mean relative WAR after four weeks was 46.3% (95% confidence interval (CI): 36.5, 56.2%) in the full analysis set (n=49). In the sensitivity analysis based on the ITT population, it was 43.9% (95% CI: 33.1, 54.7%). In total, three AEs were found to be related to the investigational device; all were non-serious.</p><p><strong>Conclusion: </strong>In this study, treatment of VLUs with the investigational device showed that the mean relative WAR after four weeks of treatment was 46.3%. This reduction in wound area is comparable to the performance of other silver-containing wound dressings. In addition, the results of this clinical investigation revealed no safety concerns. Thus, the study demonstrated that the investigational device is both a safe dressing and one that performs as intended to facilitate VLU healing.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 12","pages":"961-969"},"PeriodicalIF":1.7,"publicationDate":"2025-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145678049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment response time in a patient with hard-to-heal ulcers: a case report.","authors":"Hilal Özkaya, Başak Korkmazer, Yağmur Dündar Nacar, Orkun Celil Sel","doi":"10.12968/jowc.2021.0116","DOIUrl":"https://doi.org/10.12968/jowc.2021.0116","url":null,"abstract":"<p><p>Approximately 1% of skin cancers occur secondary to chronic inflammation, and approximately 95% of these are squamous cell carcinomas (SCC) with a metastasis rate of 20-30%. This case report describes the treatment of a 38-year-old male patient with paraplegia and with a history of operated meningomyelocele and congenital hip dysplasia who was admitted to the emergency service of the Basaksehir Cam ve Sakura City Hospital (Istanbul, Turkey) with complaints of bleeding, discharge and pain from a hard-to-heal (chronic) pressure ulcer (PU) in the right gluteal region. The patient had a haemorrhagic and ulcero-vegetant mass/wound of approximately 20×20cm with vegetative satellite lesions located in the right gluteal region extending to the sacral region. <i>Acinetobacter baumannii</i> was growing in the wound culture and appropriate antibiotherapy was initiated followng the recommendation of the infectious diseases clinic. The patient was started on a protein-rich diet, with parenteral paracetamol and non-steroid anti-inflammatory drugs for wound care and pain relief. Pathological examination of the tissue biopsy detected SCCs. According to the pelvic magnetic resonance imaging and positron emission tomography-computed tomography results, the mass was considered inoperable and radiotherapy was administered for wound palliation with the help of the radiation oncology clinic. After 13 sessions of radiotherapy, haemorrhage of the ulcer ceased and the mass showed minor regression. This case report demonstrates that it is important to follow-up on patients with hard-to-heal PUs who are fully or partially bedbound. This can be performed by home health services or family physicians in primary care. If the treatment process is prolonged in palliative care patients with hard-to-heal wounds, requesting further examinations when malignant transformations are observed may create the opportunity for an early diagnosis, which can improve their quality of life. <b>Declaration of interest:</b> The authors have no conflict of interest.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 Sup12b","pages":"c-cii"},"PeriodicalIF":1.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145678008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of extracorporeal shock wave therapy for wounds and musculoskeletal treatment: a systematic review.","authors":"Tanner J Howard, Leah Amir, Matthew J Regulski, John D Mullins","doi":"10.12968/jowc.2024.0113","DOIUrl":"https://doi.org/10.12968/jowc.2024.0113","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this systematic review was to assess the healing performance of extracorporeal shock wave therapy (ESWT) on integumentary wounds and musculoskeletal tissue injury.</p><p><strong>Method: </strong>Using PubMed and Google Scholar, a systematic search was conducted in June 2021 on randomised controlled trials (RCTs) that assessed treatment efficacy of ESWT on wounds or musculoskeletal tissue injuries. Reviewed studies were stratified by target tissue and energy density level, and assessed for risk of bias. Outcome measures reported in more than one reviewed study on the same target tissue were pooled and graded for quality of evidence.</p><p><strong>Results: </strong>A total of 296 records were considered and 14 eligible studies reviewed. Experimental design varied across studies, with ESWT applied at energy densities ranging from 0.08-0.58mJ/mm². The performance of ESWT matched or exceeded that of placebo-controlled treatments and/or standard of care in all reviewed studies. In addition, 12 studies-including all studies on wounds-reported significantly faster tissue healing and/or greater pain reduction with ESWT compared with the comparator treatment(s). Evidence from pooled analyses favoured ESWT and ranged from very low to moderate in quality.</p><p><strong>Conclusion: </strong>The findings of this systematic review suggested that ESWT supported wound healing and is a promising treatment method for musculoskeletal tissue injuries. An implementation of standardised, tissue-specific ESWT protocols will benefit future evidence-based investigations that compare findings between studies on the same targeted tissue. Additional results from well-designed, appropriately powered RCTs will aid decision-making and further inform the clinical evidence of the tissue healing benefits provided by ESWT.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 Sup12a","pages":"S5-S16"},"PeriodicalIF":1.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145678046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implementation of strategies to reduce and manage hospital-acquired pressure ulcers: a qualitative improvement programme.","authors":"Michela Bottega, Sandra Migotto, Stefania Avoni, Dalmazio Vedelago, Francesca Rigo, Johnny Bordignon, Mara Tonegutti, Cristina Piotto, Paola Salvador, Alberto Coppe","doi":"10.12968/jowc.2023.0327","DOIUrl":"https://doi.org/10.12968/jowc.2023.0327","url":null,"abstract":"<p><strong>Objective: </strong>To describe a quality improvement project based on the 'Standards for Quality Improvement Reporting Excellence' (SQUIRE) guidelines, to implement care bundles for pressure ulcer (PU) prevention and management.</p><p><strong>Method: </strong>The study was conduct in the medical, surgical and intensive care departments of six hospitals in northern Italy, between 2002 and 2020. The data collection was carried out by the unit's nurses and nurse managers. Implementation strategies included the dissemination of the PUs standard of care, the engagement of the unit nurses' mangers, the definition and the adoption of a clinical tool for PU risk assessment, the decision algorithm for the Braden score range and the class of air surface, the definition of PUs being monitored and the auditing system.</p><p><strong>Results: </strong>The development of a quality improvement programme allowed the authors to invest in a structured plan of organisational interventions, which impacted different areas such as leadership, staffing, information technology, performance and improvement. There was no significant change in the prevalence of PUs, which remained at around 11%, but the improvement program allowed for standardisation of PU risk assessment and the supply of air mattresses in the company. Therefore, an evidence-based PU prevention and management bundle, drafter by a multidisciplinary team, was implemented at the six hospitals.</p><p><strong>Conclusion: </strong>Despite PU quality improvement programmes promoting healthcare professionals' adherence to evidence-based practice, demonstrating a measurable reduction in PU rates can be challenging in real-world settings. However, standardising clinical practice can generate reliable data to support targeted investments in nursing care and help establish an audit framework for evaluating clinical and organisational outcomes.</p><p><strong>Declaration of interest: </strong>The authors have no conflict of interest to declare.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 Sup12b","pages":"lxxxix-xcix"},"PeriodicalIF":1.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145677989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimal excision time for burn injuries of over 20% total body surface area: a retrospective review.","authors":"Tomer Lagziel, Arya A Akhavan, Feras Shamoun, Sophie Cemaj, Joshua Yoon, Sohayla Rostami, Qingwen Kawaji, Stephanie L Martinez, Eliana F R Duraes, Julie A Caffrey, C Scott Hultman","doi":"10.12968/jowc.2024.0058","DOIUrl":"https://doi.org/10.12968/jowc.2024.0058","url":null,"abstract":"<p><strong>Objective: </strong>While early excision of burn wounds is known to improve outcomes, the precise optimal timing within the early period remains unclear. A previous study by the authors suggests possible superiority in outcomes associated with immediate/expedited excision. This study aims to assess whether there is a difference in outcomes if initial excision is performed immediately (<24 hours), expedited (24-72 hours), or early (3-6 days) in adults with burns-related injuries of >20% total body surface area (TBSA).</p><p><strong>Method: </strong>The authors performed a retrospective review of adults admitted to the Johns Hopkins Burn Center (Baltimore, US). The authors stratified the study groups based on pre-established definitions of time-to-excision: immediate (<24 hours); expedited (24-72 hours); and early (3-6 days). They assessed: blood-loss during the initial surgery; transfusion requirements; pain levels; daily analgesic requirements; complications; readmissions; length of stay (LoS) and mortality.</p><p><strong>Results: </strong>The records of 1035 adult patients were reviewed, of which 99 patients with >20% TBSA required excision. Data showed 10 patients were in the immediate group, 63 in the expedited group, and 26 in the early group. Patients in the expedited group had significantly (p<0.05) greater blood loss, transfusion requirements, pain scores, analgesic requirements, readmissions, LoS and mortality than patients in the immediate and early groups.</p><p><strong>Conclusion: </strong>The findings of this review suggest a bimodal optimal time-to-excision of 'immediately' or 'early'. The expedited group appeared to have worse outcomes. The immediate group had favourable outcomes, possibly due to the removal of the inflammatory nidus before systemic dysfunction took place, while the early group had favourable outcomes possibly due to the resolution and stabilisation of the patients' haemodynamic and inflammatory status. Based on the authors' data, immediate (<24 hours) and early (3-6 days) excision of burns are superior to expedited excision (24-72 hours). These results strongly argue in favour of a randomised, controlled trial to help define the optimal timing of burn wound excision.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 Sup12a","pages":"S25-S30"},"PeriodicalIF":1.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145678025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Disparities in pressure ulcer flap reconstruction associated with barriers to accessing postoperative care.","authors":"Peter M Vonu, Michael Ali, Rachel H Safeek, Rolando Otero, Sarah Virk, Harvey Chim, Ellen S Satteson","doi":"10.12968/jowc.2022.0172","DOIUrl":"10.12968/jowc.2022.0172","url":null,"abstract":"<p><strong>Background: </strong>Flap reconstruction for pressure ulcers remains a surgical challenge, requiring careful selection of suitable patients to optimise outcomes. Postoperative care, especially pressure offloading, is critical for the prevention of complications, which include failure of the skin flap and wound recurrence. While the rates and risks of postoperative complications have been acknowledged, the challenges of postoperative care have been largely unaddressed.</p><p><strong>Method: </strong>A 10-year retrospective review of all patients undergoing flap reconstruction for pressure ulcers at the College of Medicine (University of Florida, Florida, US) was conducted to elucidate factors that affected delays to discharge, post-discharge disposition (where the patient is discharged to), postoperative care and associated complications.</p><p><strong>Results: </strong>Among patients who underwent multiple separate reconstructions, disposition to home versus a skilled nursing facility (SNF) or long-term acute care hospital (LTACH) had a significant association with a higher risk of complications.</p><p><strong>Conclusion: </strong>In these high-risk patients, a multidisciplinary approach that would ideally be put in place preoperatively should be used to optimise postoperative care and prevent unnecessary prolonged hospitalisation.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 Sup12a","pages":"S17-S24"},"PeriodicalIF":1.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145678010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Burn injuries in the Asia-Pacific region: Use of polyhexamethylene biguanide and betaine surfactant (PHMB-B) for wound bed preparation in children and adults.","authors":"Harikrishna Kr Nair, Pornprom Muangman, Yan Liu, Kerrie Coleman, Wipawee Kanpuan, Mohd Shahrul Suondoh, Salmi Mohamed Sukur, Anchan Ketmek, Suttipong Tianwattanatada, Suchada Kittidacha, Orapin Taengthet, Wen Liang Wang, Min Gao, Zong Qi Yin, Yi Dou, Jia Jun Zhu, Chenlu Song, Gai Zhang, Xuechuan Li, Huizhong Yang, Duong Van Phu, Nguyen Hai An, Claudine Rosario B Lukban, Gerald Marion M Abesamis, Ralf V Santamaria, Fernando A Acance, Deni Alia Yadi, Amelia Ganefianty, Abdurrahman Hakim, Chamath Sachindra Angulugaha, Gayan Ekanayake, Svp Wimalarathna, Mohd Shahrul Suondoh, Salmi Mohamed Sukur, Thanchanock Sawangsangwattana, Tippawan Wattanakham, Amarmend Ganbat","doi":"10.12968/jowc.2025.34.Sup12c.S1","DOIUrl":"https://doi.org/10.12968/jowc.2025.34.Sup12c.S1","url":null,"abstract":"<p><p>This case-series supplement serves as an educational resource for health professionals involved in the care of burn injuries. Drawing from clinical experiences across healthcare settings in the Asia-Pacific region, the supplement focuses on the use of polyhexamethylene biguanide and betaine surfactant (PHMB-B) solution, gel and high-viscosity gel, alone or in combination, in managing both thermal and non-thermal burns, including partial-thickness and full-thickness burns, in both paediatric and adult populations. In alignment with international guidance, this supplement reinforces the recommendation to integrate PHMB-B into routine practice. The broad-spectrum antimicrobial activity, low cytotoxicity and biofilm-disruptive properties of this combined solution is clinically appropriate for use in complex burn wounds, where infection control and optimal healing conditions are crucial to wound healing.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 Sup12c","pages":"S1-S20"},"PeriodicalIF":1.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145678013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The rise of intelligent tissue engineering: the new CAMP frontier.","authors":"Windy Cole","doi":"10.12968/jowc.2025.0549","DOIUrl":"https://doi.org/10.12968/jowc.2025.0549","url":null,"abstract":"","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 Sup12a","pages":"S3-S4"},"PeriodicalIF":1.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145678020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cellular, Acellular And Matrix-Like Products (CAMPS) In Pressure Injuries.","authors":"Michael Desvigne, William H Tettelbach, Thomas Davenport, Ryan Dirks, Martha R Kelso, Mervin Low, Michael Bain, John Lantis, Catherine Milne, Betsy Reynolds, Zweli Tunyiswa","doi":"10.12968/jowc.2025.34.Sup12d.S1","DOIUrl":"https://doi.org/10.12968/jowc.2025.34.Sup12d.S1","url":null,"abstract":"","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 Sup12d","pages":"S1-S20"},"PeriodicalIF":1.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145768699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Punch grafting for necrotising fasciitis: a case report.","authors":"Chiara Ceolin, Marina De Rui, Francesco Barcaro, Giuseppe Sergi, Piero Baù","doi":"10.12968/jowc.2023.0033","DOIUrl":"10.12968/jowc.2023.0033","url":null,"abstract":"<p><p>Until recently, autologous punch grafting was reported for the treatment of vitiligo and other skin diseases such as nevus depigmentosus, piebaldism and postinflammatory or chemical leukoderma, as well as for ulcers and leg lesions. However, no studies have investigated its use in managing complications arising from necrotising fasciitis, to the best of the authors' knowledge. Given the nature of this bacterial infection-which affects the full thickness of the skin in the lower limbs-the favourable results achieved with punch grafting in ulcers suggest promise for its application in necrotising fasciitis as well. The authors present the case of an older male patient with necrotising fasciitis on the left leg, treated with autologous punch grafting. His medical history included obliterative arteriopathy, type II diabetes, and orthotopic heart transplantation under immunosuppressive therapy. He was hospitalised for cellulitis with tissue necrosis. After antibiotic therapy and surgical debridement, he was treated with autologous punch grafting from April to October 2021. By the end of treatment, complete restoration of skin integrity was achieved. In conclusion, autologous punch grafting may represent a valuable alternative for treating extensive ulcerations caused by necrotising fasciitis-particularly in immunocompromised patients-given its technical simplicity and the resulting improvement in quality of life.</p>","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"34 11","pages":"941-943"},"PeriodicalIF":1.7,"publicationDate":"2025-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145471289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}