Journal of wound care最新文献_第8页

Posture, mobility and pressure signatures of community dwelling individuals with pressure ulcers: stratifying exposure to support personalised care. 患有压疮的社区居民的姿势、活动能力和压力特征：分层暴露以支持个性化护理。

IF 1.5 4区医学

Journal of wound care Pub Date : 2024-09-02 DOI: 10.12968/jowc.2024.0199

Silvia Caggiari, Peter Worsley, Nicci Aylward-Wotton

引用次数: 0

What is the impact of care bundles on the prevalence or incidence of pressure ulcers among at risk adults in the acute care setting? A systematic review. 护理捆绑包对急症护理环境中高风险成人的压疮流行率或发病率有何影响？系统综述。

IF 1.5 4区医学

Journal of wound care Pub Date : 2024-09-02 DOI: 10.12968/jowc.2024.0200

Áine Curtis, Rosemarie Derwin, Gráinne Milne, Anne Marie Connor, Linda Nugent, Zena Moore

引用次数: 0

Efficacy and safety of autologous whole blood clot in diabetic foot ulcers: a randomised controlled trial. 自体全血凝块治疗糖尿病足溃疡的有效性和安全性：随机对照试验。

IF 1.5 4区医学

Journal of wound care Pub Date : 2024-09-02 Epub Date: 2024-08-30 DOI: 10.12968/jowc.2024.0195

Robert Snyder, Aksone Nouvong, Jesus Ulloa, Naz Wahab, Terry Treadwell, Febe Bruwer, Liezl Naude, James McGuire, Alexander M Reyzelman, Timothy Graham, Rene Lessing, Eric Lullove, Emre Ozker, Hau T Pham, Michael Pasternac, Shira Cohen

{"title":"Efficacy and safety of autologous whole blood clot in diabetic foot ulcers: a randomised controlled trial.","authors":"Robert Snyder, Aksone Nouvong, Jesus Ulloa, Naz Wahab, Terry Treadwell, Febe Bruwer, Liezl Naude, James McGuire, Alexander M Reyzelman, Timothy Graham, Rene Lessing, Eric Lullove, Emre Ozker, Hau T Pham, Michael Pasternac, Shira Cohen","doi":"10.12968/jowc.2024.0195","DOIUrl":"10.12968/jowc.2024.0195","url":null,"abstract":"Objective: Diabetic foot ulcers (DFUs) present a significant global health challenge, resulting in high morbidity and economic costs. Current available treatments often fail to achieve satisfactory healing rates, highlighting the need for novel therapies. This study evaluated the safety and efficacy of a novel autologous whole blood clot (AWBC)-a blood-based, biodegradable provisional matrix-in conjunction with standard of care (SoC) when compared to SoC alone in the treatment of hard-to-heal DFUs.Method: A multicentre, prospective, blinded assessor, randomised controlled trial was conducted at 16 sites across the US, South Africa and Turkey. A cohort of patients with hard-to-heal DFUs was enrolled and randomised to either the AWBC group or the control group. The primary endpoint was complete wound closure at 12 weeks, while secondary endpoints included time to heal and percentage area reduction (PAR) at four and eight weeks. Data were analysed using both intention-to-treat (ITT) and per-protocol (PP) populations.Results: The cohort included 119 patients. AWBC treatment resulted in a significantly higher healing rate compared to the control in both ITT (41% versus 15%, respectively; p=0.002) and PP populations (51% versus 18%, respectively; p=0.0075). AWBC treatment also resulted in a shorter mean time to heal and higher durability of wound closure. Safety analysis showed a similar incidence of adverse events (AEs) between groups, with no device-related AEs.Conclusion: The AWBC system, by modulating the wound microenvironment and providing a functional extracellular matrix, offered a promising new approach to treating hard-to-heal DFUs, demonstrating superior healing outcomes compared to SoC alone in this study.","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"33 9","pages":"688-700"},"PeriodicalIF":1.5,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142290192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Catastrophic antiphospholipid syndrome: a case report and literature review. 灾难性抗磷脂综合征：病例报告和文献综述。

IF 1.5 4区医学

Journal of wound care Pub Date : 2024-09-01 DOI: 10.12968/jowc.2024.0285

Jun Kyoung, Lauren Workman, Taylor Spurgeon-Hess, Kirollos S Tadrousse, Drew Oostra, Richard Simman

引用次数: 0

Percentage area reduction at week 4 as a prognostic indicator of complete healing in patients treated with standard of care: a post hoc analysis. 第 4 周时面积缩小的百分比作为标准疗法患者完全愈合的预后指标：事后分析。

IF 1.5 4区医学

Journal of wound care Pub Date : 2024-09-01 DOI: 10.12968/jowc.2024.0141

Thomas Serena, Sadia Yaakov, Raphael Yaakov, Emily King, Vickie R Driver

{"title":"Percentage area reduction at week 4 as a prognostic indicator of complete healing in patients treated with standard of care: a post hoc analysis.","authors":"Thomas Serena, Sadia Yaakov, Raphael Yaakov, Emily King, Vickie R Driver","doi":"10.12968/jowc.2024.0141","DOIUrl":"https://doi.org/10.12968/jowc.2024.0141","url":null,"abstract":"Early indicators of healing provide valuable information on the potential benefit of treatment. In patients with hard-to-heal (chronic) diabetic foot ulcers (DFUs), timely intervention is critical. Ulcers that fail to show measurable progress within four weeks of treatment are considered recalcitrant. These ulcers increase the risk of soft tissue infection, osteomyelitis and lower extremity amputation. A prognostic indicator or surrogate marker allows for rapid evaluation of treatment efficacy and safety. An inverse correlation between a percentage area reduction (PAR) of ≤50% at week 4 and complete healing by week 12 has been previously established; however, the data were derived from a standard of care (SoC) arm of clinical trials that are over a decade old. In this post hoc analysis, data from a large multicentre prospective randomised controlled trial were reviewed to assess PAR at week 4 as a prognostic indicator in patients treated with SoC. Overall, 65.4% (17/26) of patients with PAR >50% at week 4 achieved complete closure at week 12. The receiver operating characteristic (ROC) curve for area reduction by week 4 showed strong discrimination for predicting non-healing (area under the ROC curve: 0.92; p<0.001; positive predictive value: 70.6%; negative predictive value: 87.2%). These findings are consistent with previous studies and support the use of four-week PAR as a prognostic indicator.","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"33 Sup9","pages":"S36-S42"},"PeriodicalIF":1.5,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142290138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The unavoidable pressure injury/ulcer: a review of skin failure in critically ill patients. 不可避免的压伤/溃疡：重症患者皮肤衰竭回顾。

IF 1.5 4区医学

Journal of wound care Pub Date : 2024-09-01 DOI: 10.12968/jowc.2024.0079

Kelsee K Zajac, Kathryn Schubauer, Richard Simman

{"title":"The unavoidable pressure injury/ulcer: a review of skin failure in critically ill patients.","authors":"Kelsee K Zajac, Kathryn Schubauer, Richard Simman","doi":"10.12968/jowc.2024.0079","DOIUrl":"https://doi.org/10.12968/jowc.2024.0079","url":null,"abstract":"Due to an ageing population and prolonged lifespan, pressure injury (PI) incidence is increasing. Patients with a PI typically endure longer hospital stays, which create a significant burden on healthcare resources and costs. With appropriate preventive interventions, most PIs can be avoided; however, skin failure may become inevitable in particular instances. These are classified as unavoidable PIs. Patients in a critical condition are exposed to a unique set of therapies, medications and bodily states. Oftentimes, these instances decrease tissue tolerance, which may promote PI formation. Patients who are critically ill, especially those with extended stays in the intensive care unit, are susceptible to skin failure due to: prolonged immobility; mechanical ventilation; acute respiratory distress syndrome; COVID-19; sepsis; multiorgan system dysfunction; vasopressor use; and treatment with extracorporeal membrane oxygenation. Poor perfusion leading to skin breakdown results from the compounding factors of circulatory collapse, build-up of metabolites, compromised lymphatic drainage, patient comorbidities, and ischaemia via capillary blockage in patients who are critically ill. In addition, similar physiology is present during end-of-life multisystem organ failure, which creates unavoidable skin deterioration. The aim of this review is to provide an overview of circumstances which decrease tissue tolerance and ultimately lead to PI development, despite adequate preventive measures in patients who are critically ill.","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"33 Sup9","pages":"S18-S22"},"PeriodicalIF":1.5,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142290139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Use of three-dimensional acellular collagen matrix in deep or tunnelling diabetic foot ulcers: a retrospective case series. 在深层或隧道型糖尿病足溃疡中使用三维无细胞胶原基质：回顾性病例系列。

IF 1.5 4区医学

Journal of wound care Pub Date : 2024-09-01 DOI: 10.12968/jowc.2024.0176

Raymond J Abdo, Amy L Couch

{"title":"Use of three-dimensional acellular collagen matrix in deep or tunnelling diabetic foot ulcers: a retrospective case series.","authors":"Raymond J Abdo, Amy L Couch","doi":"10.12968/jowc.2024.0176","DOIUrl":"https://doi.org/10.12968/jowc.2024.0176","url":null,"abstract":"Objective: While most xenograft wound matrices are flat sheets not designed for deep or tunnelling wounds, three-dimensional acellular collagen matrices (3D-ACM) can fill deep wound beds and enable full wound wall apposition. This case series examines the use of 3D-ACM in treating diabetic foot ulcers (DFUs) that are deep, tunnelling, undermining, or irregularly shaped. We report outcomes of cases where 3D-ACM was applied to deep or tunnelling DFUs present for at least four weeks.Method: In this retrospective case series, 3D-ACM was applied, healing was monitored and measurements were collected. Additional 3D-ACM was applied as needed.Results: In total, 11 patients with 13 wounds were treated. Improved wound appearance and reduced size were observed at most follow-ups. Mean initial wound depth was 1.6cm, and several wounds showed significant depth reductions shortly after therapy initiation. In total, 62% of wounds (8/13) reached 50% closure by four weeks. Additionally, 54% (7/13) were fully closed by 12 weeks. The remaining 46% (6/13) took between 12-22.3 weeks to heal. Overall mean therapy time was 13.1 weeks (range: 2.0-22.3 weeks). Deeper wounds generally took longer to close.Conclusion: The findings of this case series showed that 3D-ACM could offer a protective microenvironment for wound management for deep or tunnelling DFUs. While some took >12 weeks to close, this may be attributable to large initial depths and volumes, rather than a failure to respond to the treatment modality. Other wounds that require a conforming 3D matrix, enabling full wound wall apposition, may benefit from 3D-ACM. Further investigations would be beneficial to understand the capabilities of this treatment modality.","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"33 Sup9","pages":"S5-S16"},"PeriodicalIF":1.5,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142290141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Below-knee amputation with an ultrasonic scalpel: evaluation of early postoperative clinical outcomes. 使用超声刀进行膝下截肢术：术后早期临床效果评估。

IF 1.5 4区医学

Journal of wound care Pub Date : 2024-09-01 DOI: 10.12968/jowc.2021.0015

Hyun Jung Ryoo, Yeon Ji Lee, Jin-Soo Lim, Hyung-Sup Shim

{"title":"Below-knee amputation with an ultrasonic scalpel: evaluation of early postoperative clinical outcomes.","authors":"Hyun Jung Ryoo, Yeon Ji Lee, Jin-Soo Lim, Hyung-Sup Shim","doi":"10.12968/jowc.2021.0015","DOIUrl":"https://doi.org/10.12968/jowc.2021.0015","url":null,"abstract":"Objective: Despite the development of microscopic reconstructive techniques for lower limb salvage, major limb amputation is still required for critical, unsalvageable lower leg wounds, with steadily increasing estimates of major limb amputations. In this study, the authors highlight a surgical technique for below-knee (BK) amputation using an ultrasonic scalpel, and evaluate its safety and effectiveness compared with the conventional method of using surgical blades.Method: A retrospective chart review was conducted at the Department of Plastic and Reconstructive Surgery, St. Vincent's Hospital, Republic of Korea, on patients who underwent BK amputation between October 2012 and January 2021. Patients were assigned to two groups: amputation using classical methods, such as surgical blades and electrocautery (group A); and amputation using an ultrasonic scalpel (group B). Numerous perioperative factors, such as operation time, intraoperative blood loss, postoperative complications and recovery time were examined. The present study adhered to the STROBE guidelines.Results: A total of 41 patients (16 in group A and 25 in group B) were included in this study. Operation time was significantly shorter in group B (p=0.001) and intraoperative blood loss was lower (p=0.011). Wound healing time did not vary between groups.Conclusion: In this study, the use of an ultrasonic scalpel for lower limb amputation was effective in reducing operation time and blood loss, which may be helpful in improving outcomes for patients with comorbidities.","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"33 Sup10a","pages":"ccxii-ccxix"},"PeriodicalIF":1.5,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142391540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ACCWS Wound Care Symposium at the AVLS Annual Congress 2024. 在 AVLS 2024 年年会上举办 ACCWS 伤口护理专题讨论会。

IF 1.5 4区医学

Journal of wound care Pub Date : 2024-09-01 DOI: 10.12968/jowc.2024.0298

引用次数: 0

The use of a multimodal wound matrix to treat a variety of hard-to-heal wounds: a case series surveillance. 使用多模式伤口基质治疗各种难以愈合的伤口：病例系列监测。

IF 1.5 4区医学

Journal of wound care Pub Date : 2024-09-01 DOI: 10.12968/jowc.2024.0135

David Swain, Windy Cole, Christopher Barrett, Gregory Black, Carmen Hudson, Michael Lacqua, Jacob Reinkraut, Omar Jalil, Robert McLafferty

{"title":"The use of a multimodal wound matrix to treat a variety of hard-to-heal wounds: a case series surveillance.","authors":"David Swain, Windy Cole, Christopher Barrett, Gregory Black, Carmen Hudson, Michael Lacqua, Jacob Reinkraut, Omar Jalil, Robert McLafferty","doi":"10.12968/jowc.2024.0135","DOIUrl":"https://doi.org/10.12968/jowc.2024.0135","url":null,"abstract":"Objective: This case series examines the use of a multimodal wound matrix (MWM) trialled in a selection of clinical practice settings and on a variety of hard-to-heal wounds. The objective was to evaluate the effects of MWM and its performance in managing such wounds, regardless of clinical setting and ulcer type.Method: Treatment of the MWM was conducted by independent wound care practitioners on wounds that were of >4 weeks duration. Treatment was once a week. Assessment was taken after four weeks and at week 12 of the study to assess percentage area reduction (PAR) compared to baseline measurements taken at the first treatment visit. Complete (100%) re-epithelialisation was also recorded.Results: A total of 63 wounds were treated with MWM, and ulcer types were grouped as: diabetic foot ulcers (n=21); venous leg ulcers (n=18); pressure injuries (n=10); and others (n=14). Of the wounds, 78% had 100% re-epithelialisation, with an average PAR of 57% at four weeks and 86% at 12 weeks. The average time to resolution for those wounds that closed was 7.9 weeks.Conclusion: Results from this series of independent case studies support the application of MWM to potentially benefit healing in hard-to-heal wounds of different aetiologies of any duration and in a variety of clinical settings.","PeriodicalId":17590,"journal":{"name":"Journal of wound care","volume":"33 Sup9","pages":"S27-S35"},"PeriodicalIF":1.5,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142290140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0