Journal of Veterinary Diagnostic Investigation最新文献

{"title":"Mammary neuroendocrine tumor in a mare.","authors":"Ryan Jordan, Fabian Roa, Amy Santonastaso, Francisco A Uzal, Valentina Stevenson","doi":"10.1177/10406387261456253","DOIUrl":"10.1177/10406387261456253","url":null,"abstract":"<p><p>A 10-y-old American Paint Horse mare was presented to the Equine Field Services at Virginia-Maryland College of Veterinary Medicine (Blacksburg, VA, USA) for evaluation of mastitis and a possible abscess in the right mamma. Histologic evaluation of a mammary biopsy revealed a densely cellular, infiltrative neoplasm with cells arranged in packets supported by thin stroma. In a neuroendocrine immunohistochemistry panel, the neoplastic cells did not immunolabel for neuron-specific enolase or synaptophysin, positively immunolabeled for chromogranin A, and had moderate scattered immunolabeling for S100. These findings confirmed a diagnosis of mammary neuroendocrine tumor. Although the cells also did not immunolabel for cytokeratin, we cannot rule out a neuroendocrine carcinoma. Neuroendocrine mammary neoplasms are very rare and, to our knowledge, they have not been reported previously in horses. This neoplasm should be considered as a differential diagnosis for mammary tumors in mares.</p>","PeriodicalId":17579,"journal":{"name":"Journal of Veterinary Diagnostic Investigation","volume":" ","pages":"1267-1271"},"PeriodicalIF":1.4,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13332941/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148382241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Presumptive primary mammary gland squamous cell carcinoma with widespread metastases in a young ewe.","authors":"Sebastian Alessandro Mignacca, Stefano Bagatella, Vanessa Zambelli, Francesca Spada, Laura Zarucco, Maria Teresa Capucchio","doi":"10.1177/10406387261470797","DOIUrl":"10.1177/10406387261470797","url":null,"abstract":"<p><p>Mammary tumors in sheep are exceedingly rare, with all reported cases being benign to noninvasive and slow growing. Here, we describe a squamous cell carcinoma (SCC) with widespread metastases presumptively arising from the mammary parenchyma in a 3.5-y-old ewe. Following a history of chronic mastitis and severe swelling of the udder, the udder was removed surgically and submitted for examination. Three weeks after surgery, because of poor prognosis, the animal was euthanized and autopsied. The udder had no cutaneous lesions but had parenchymal disorganization and extensive areas of necrosis delimiting large, fluid-filled cavities. Two cord-like masses extended from the mammary gland into the pelvic cavity and subcutis of the right hindlimb. Numerous nodules were observed within the mammary and abdominal lymph nodes, peritoneum, lungs, and heart. Histologically, mammary and extramammary lesions consisted of neoplastic squamous epithelial cells, often surrounding keratinized cores. Neoplastic cells had diffuse cytoplasmic immunolabeling for pancytokeratin, confirming their epithelial lineage. Non-keratinized neoplastic cells were positive for p63 and, infrequently, for cytokeratin 19, suggesting mammary histogenesis. Considering the lack of a primary extramammary mass and the tumoral immunophenotype, a presumptive diagnosis was made of primary mammary SCC with metastasis to multiple organs. The aggressive clinical behavior of this neoplasm contrasts with that of reported ovine mammary neoplasms and cutaneous SCCs.</p>","PeriodicalId":17579,"journal":{"name":"Journal of Veterinary Diagnostic Investigation","volume":" ","pages":"1350-1356"},"PeriodicalIF":1.4,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13423948/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148620740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genotypic characterization of bovine rotavirus A from diagnostic submissions from 9 U.S. states, 2020-2025.","authors":"Ahsan Naveed, Colin Brewer, Liping Xie, Seth Lewin, John Dustin Loy, Duan Sriyotee Loy","doi":"10.1177/10406387261471139","DOIUrl":"10.1177/10406387261471139","url":null,"abstract":"<p><p>Bovine rotavirus A is a major cause of neonatal calf diarrhea and can lead to significant economic losses for cattle producers. Studying genotypic diversity among circulating RVA strains is critical to understanding virus epidemiology and to enhancing vaccine development. We identified 1,515 fecal samples from calves with enteric disease. Samples originated from 9 U.S. states and were submitted to the Nebraska Veterinary Diagnostic Center between 2020-2025 for bovine rotavirus A (RVA) testing. Of these 1,515 samples, 540 tested positive by reverse-transcription quantitative real-time PCR (RT-qPCR), and 76 were genotyped. Among VP7 (G-type) and VP4 (P-type) genes, G6P[5] were most frequent (36 of 76), followed by G10P[11] (12 of 76) and G6P[11] (7 of 76); 15 samples were partially genotyped. Five isolates (3 G8P[1] and 2 G6P[5] strains) were cultured in MA-104 cells and sequenced using long-read nanopore technology. In phylogenetic analysis, all isolates clustered within established bovine RVA genotype lineages and included both closely related strains and distinct sub-lineages. Our descriptive findings indicate that a diverse set of viruses circulates in U.S. cattle, and we offer sequence data for comparison with previously reported strains.</p>","PeriodicalId":17579,"journal":{"name":"Journal of Veterinary Diagnostic Investigation","volume":" ","pages":"1308-1313"},"PeriodicalIF":1.4,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13473325/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148713094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Asymmetric urinary lesions associated with <i>Proteus mirabilis</i> infection in a beef calf.","authors":"Chihiro Kanno, Reina Kanazashi, Shogo Sato, Yosuke Maeda, Ayano Sasaki, Ryo Ando, Taishi Tanabe, Fumiaki Takahashi","doi":"10.1177/10406387261479226","DOIUrl":"10.1177/10406387261479226","url":null,"abstract":"<p><p>An 8-mo-old Japanese Black beef heifer calf was presented with anorexia, dysuria, and abdominal pain. Ultrasonographically, the left renal pelvis and calyces were markedly dilated and contained numerous calculi; the right renal pelvis was filled with hyperechoic material without obvious calculi. Despite supportive care and antimicrobial treatment with ceftiofur, the calf died 4 d after presentation. Autopsy revealed severe hydronephrosis with numerous struvite calculi in the left kidney and advanced pyonephrosis in the right kidney. <i>Proteus mirabilis</i> was isolated antemortem from urine and postmortem from purulent material in both kidneys, ureters, urinary bladder, and an associated urachal remnant abscess. As found in our case, <i>P. mirabilis</i> infection in cattle can be associated with both obstructive and suppurative renal lesions within a single animal. Our case emphasizes the importance of comprehensive diagnostic investigation, including bilateral renal ultrasonography and thorough bacteriologic evaluation, and offers diagnostic insight into the variable pathologic manifestations of <i>P. mirabilis</i>-associated urinary tract disease in cattle.</p>","PeriodicalId":17579,"journal":{"name":"Journal of Veterinary Diagnostic Investigation","volume":" ","pages":"1336-1340"},"PeriodicalIF":1.4,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13541992/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148887924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the Sidekick point-of-care progesterone lateral-flow assay for use in equine reproductive management.","authors":"Sara H McDowell, Andrew McLain, Luca Moore, Craig J Ledgerwood, Elizabeth Bailie, Tara Moore","doi":"10.1177/10406387261460834","DOIUrl":"10.1177/10406387261460834","url":null,"abstract":"<p><p>A point-of-care (POC; stall-side) test for progesterone that delivers rapid, accurate results has the potential to transform equine reproductive care. We evaluated the analytical and clinical performance of a POC device (Sidekick) that incorporates a progesterone lateral-flow assay (LFA) with a reader, and compared it with established methods (radioimmunoassay [RIA] and chemiluminescence immunoassay [CLIA]). Analytical performance was assessed using serially diluted mare plasma (0-8 ng/mL progesterone) to estimate precision and percent recovery. Clinical accuracy was assessed by comparison with RIA and CLIA on 19 paired serum samples. Agreement was evaluated by regression analyses and ordinal concordance across clinically relevant progesterone bands. The LFA had excellent recovery (90-102%) across 4-8 ng/mL, strong repeatability (CV 4-15%), and high reproducibility between 2 laboratories (CV 9.9%). Ordinal agreement with reference standards was near-perfect in spiked samples (κ = 0.94) and substantial in clinical samples versus both RIA (κ = 0.77) and CLIA (κ = 0.79). Cross-reactivity with the synthetic progestin, altrenogest, was tested at pharmacologic concentrations; no cross-reactivity was detected. Limitations of our study include an observed bias, potentially caused by the matrix differing between methods (serum vs. plasma). Additionally, a narrow validated range could cause underestimation of high concentrations. The LFA in the Sidekick device provided rapid, accurate, and clinically meaningful progesterone results in mares across 4-8 ng/mL, which would enable on-the-spot decisions and avoid delays from sample processing, transport, and result reporting.</p>","PeriodicalId":17579,"journal":{"name":"Journal of Veterinary Diagnostic Investigation","volume":" ","pages":"1238-1245"},"PeriodicalIF":1.4,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13346099/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148405053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Systemic mycobacteriosis caused by <i>Mycobacterium avium</i> subspecies <i>hominissuis</i> in a sheep.","authors":"Nagaraja Thirumalapura, Susan Bender, Manoj K Sekhwal, Patrick Camp, David Farrell, Doris Bravo, Julia Livengood, Linh Nguyen, Kimberly Lehman, Deepanker Tewari","doi":"10.1177/10406387261464590","DOIUrl":"10.1177/10406387261464590","url":null,"abstract":"<p><p><i>Mycobacterium avium</i> subsp. <i>hominissuis</i> (MAH) causes pulmonary and disseminated infections in immunocompromised humans. In pigs, MAH commonly causes subclinical infections that lead to granulomatous lesions in the mesenteric lymph nodes, liver, spleen, and jejunum. MAH infections have been reported less commonly in other animal species and in birds. Here, we report a case of systemic mycobacteriosis caused by MAH in a sheep. The affected animal had a history of hypoproteinemia, weight loss, and fever. Gross pathology findings included serous fluid accumulation in the peritoneal and pleural cavities, patchy dull granular light-red mucosa of the small intestine, diffuse orange-brown discoloration of the liver, and noncollapsing lungs that were mottled pink to dark-red. Histologically, granulomas were present in the intestines, mesenteric lymph nodes, liver, spleen, kidneys, lungs, and brain. MAH was isolated from the liver, spleen, and feces. Whole-genome sequencing revealed a mobile genetic element-an ISMAP<i>02</i>-like sequence-in the MAH genome. An ISMAP<i>02</i>-like sequence in mycobacteria other than <i>Mycobacterium avium</i> subsp. <i>paratuberculosis</i> (MAP) may interfere with the detection of MAP by PCR assays targeting ISMAP<i>02</i>.</p>","PeriodicalId":17579,"journal":{"name":"Journal of Veterinary Diagnostic Investigation","volume":" ","pages":"1380-1385"},"PeriodicalIF":1.4,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13356029/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148422179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multisystemic <i>Streptococcus gallinaceus</i> infection in a six-banded armadillo from a zoo collection.","authors":"Raúl A Resendiz-Pozos, Cassandra Lapham-Simpson, Tessa E LeCuyer, Maria Soper, Melissa Macías-Rioseco, Jennine Ochoa, Hernando D Acevedo, Todd Cornish","doi":"10.1177/10406387261470345","DOIUrl":"10.1177/10406387261470345","url":null,"abstract":"<p><p>A six-banded armadillo (<i>Euphractus sexcinctus</i>) from a zoo collection in central California developed acute neurologic signs followed by death. Postmortem examination revealed multisystemic bacterial disease (fibrinosuppurative meningoencephalomyelitis, splenitis, and endocarditis) with fibrinous necrotizing vasculitis and thrombosis. <i>Streptococcus gallinaceus</i> was isolated from the heart, lung, and meninges. To our knowledge, this microorganism has not been reported previously in association with systemic disease in an armadillo. Although the source of infection remains unknown, the animal was housed in the same building as chickens, a species that historically is associated with outbreaks of this bacterial infection. This case further broadens our understanding of the possible host range of <i>S. gallinaceus</i> and emphasizes the risk of interspecies pathogen transmission in captive environments.</p>","PeriodicalId":17579,"journal":{"name":"Journal of Veterinary Diagnostic Investigation","volume":" ","pages":"1371-1374"},"PeriodicalIF":1.4,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13473215/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148713162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Matrix extension to bovine feces and evaluation of semi-automated DNA extraction methods for the detection of <i>Campylobacter jejuni</i> in bovine and canine fecal samples using <i>gyrA</i> PCR.","authors":"Sara D Lawhon, Jing Wu, Kristy L Pabilonia, Zeinab Helal, Guillermo Risatti, Alex Nemethy, Jeremy N Ray, David Simon, Wanda Tirado, Lijuan Zhou, Paula Bartlett, Ingrid Fernandez, Susan Sanchez, Vanessa DeShambo, Namjung Jung, Carol Maddox, Steven Ensley, Udeni Balasuriya, Keith Strother, Lifang Yan, Candy Zhang, Zhenyu Shen, Shuping Zhang, Sarmila Dasgupta, Shannon Mann, Amar Patil, Laura B Goodman, Kelly Sams, Jing Cui, Melanie Prarat Koscielny, Qirui Zhang, Yan Zhang, Robin Madden, Akhilesh Ramachandran, Jessica Bower, Li Fang, Deepanker Tewari, Nagaraja Thirumalapura, Corey Zellers, Jake Guag, Sarah M Nemser, Gregory H Tyson","doi":"10.1177/10406387261454377","DOIUrl":"10.1177/10406387261454377","url":null,"abstract":"<p><p>We evaluated a semi-automated method for DNA extraction, expanded to herbivore feces a <i>gyrA</i> PCR method for the detection of <i>Campylobacter jejuni</i> in canine feces, added an internal positive control (IPC) DNA to specimens before DNA extraction, and multiplexed the <i>gyrA</i> PCR assay with the IPC assay. The addition of IPC DNA and multiplexing of the IPC assay did not affect the performance of the <i>gyrA</i> PCR assay. The method was repeatable with no significant difference in results across 6 d (F = 0.715; <i>p</i> = 0.614 with <i>R</i>² = 0.818). In a single-laboratory randomized method test evaluating detection in bovine feces, sensitivity was 96.1%, specificity was 100%, and accuracy was 94.1%. In a multi-laboratory randomized method test (M-RMT) in bovine feces, agreement was 90% between laboratories on test results with κ = 0.80 (95% CI [0.64, 0.96]). Comparison of manual DNA extraction kits with a semi-automated extraction method in canine feces found 88.9% agreement, with κ = 0.78 (95% CI [0.64, 0.92]). In a second M-RMT in canine feces, accuracy was 78% with 90% agreement between the laboratories and κ = 0.80 (95% CI [0.64, 0.96]), even though inoculation of the intended fractional level was lower than intended at 45 cfu/g feces. Overall, the <i>gyrA</i> PCR assay was extended to an additional matrix, the inclusion of an IPC DNA and assay was successful, and the <i>gyrA</i> PCR assay for the detection of <i>Campylobacter jejuni</i> provided repeatable results in multiple laboratories.</p>","PeriodicalId":17579,"journal":{"name":"Journal of Veterinary Diagnostic Investigation","volume":" ","pages":"1170-1181"},"PeriodicalIF":1.4,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13331792/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148376128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of lipemia interference on phenobarbital quantification using particle-enhanced turbidimetric inhibition immunoassay with Dimension clinical chemistry system and comparison to high-performance liquid chromatography.","authors":"Kamoltip Thungrat, Phabpim Thumarat, Alex L Jenkins, Crisanta Cruz-Espindola","doi":"10.1177/10406387261448507","DOIUrl":"10.1177/10406387261448507","url":null,"abstract":"<p><p>Phenobarbital, an anti-seizure medication with a narrow therapeutic window, requires therapeutic drug monitoring (TDM) for safe and effective use. Lipemia is a well-known interferent in turbidimetric immunoassays, yet its impact on phenobarbital quantification compared with high-performance liquid chromatography (HPLC) has not been fully characterized. We evaluated the effect of lipemia on phenobarbital measurement using a particle-enhanced turbidimetric inhibition immunoassay (PETINIA; Dimension Xpand Plus clinical chemistry system, Siemens) versus HPLC. Simulated lipemic plasma was prepared by spiking normal canine plasma with lipid emulsion to achieve predefined lipemia indices. Naturally lipemic TDM samples (index ≥ 4; <i>n</i> = 40) and non-lipemic controls (index ≤ 3, <i>n</i> = 40) were also analyzed. Phenobarbital concentrations were compared before and after lipid reduction by double microcentrifugation using both methods. HPLC performance was stable across all lipemia indices, with consistent retention times (5.0 min), accuracy and precision within acceptance limits, and high linearity (<i>R</i>² > 0.999). In contrast, PETINIA had a significant positive bias in lipemic samples, with median bias increasing from 9.1% at index 1 to 100% at index 6. Bias was significantly higher in naturally lipemic samples (median: 74.5%) compared with non‑lipemic controls (1.2%; <i>p</i> < 0.001). PETINIA and HPLC had strong agreement in non-lipemic samples (Passing-Bablok regression, <i>r</i> = 0.99), but poor agreement and proportional positive bias in lipemic samples (<i>r</i> = 0.16; slope CI [1.01, 1.89]). PETINIA overestimated phenobarbital concentrations in lipemic plasma. Microcentrifugation effectively mitigated lipemic interference and improved agreement with HPLC, supporting the use of microcentrifugation in clinical TDM workflows.</p>","PeriodicalId":17579,"journal":{"name":"Journal of Veterinary Diagnostic Investigation","volume":" ","pages":"1140-1150"},"PeriodicalIF":1.4,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13226304/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148138354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rhabdomyosarcoma in a prehensile-tailed porcupine.","authors":"Bayla Q Bessemer, Layne Staab, Jeff R Hayes, Kara N Corps, Megan E Schreeg","doi":"10.1177/10406387261460846","DOIUrl":"10.1177/10406387261460846","url":null,"abstract":"<p><p>A captive 4-y-old female prehensile-tailed porcupine (<i>Coendou prehensilis</i>) had quill loss caudal to the right ear associated with an ~1-2-cm palpable mass. The mass was surgically debulked and diagnosed histologically as a poorly differentiated neoplasm. Ten days after surgery, the porcupine became anorectic and severely ataxic with a moderate left-sided head tilt and was euthanized and submitted for postmortem examination. Deep to the surgical site was a 7 × 3 × 0.5-cm amorphous, tan, soft, irregularly shaped mass that encircled the right ear canal and invaded skeletal muscle and the right tympanic bulla. Histologically, the densely cellular, infiltrative and destructive, unencapsulated neoplasm was comprised of interlacing bundles, streams, and herringbone arrangements of spindle cells supported by scant fine stroma. Neoplastic cells invaded muscle and the bone of the tympanic bulla. Neoplastic cells had cytoplasmic immunolabeling for myogenin, myoD1, vimentin, smooth muscle actin, and desmin, and were immunonegative for S100 and CD31. The mass was diagnosed as a rhabdomyosarcoma. To our knowledge, rhabdomyosarcoma has not been reported previously in any porcupine species.</p>","PeriodicalId":17579,"journal":{"name":"Journal of Veterinary Diagnostic Investigation","volume":" ","pages":"1277-1282"},"PeriodicalIF":1.4,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13401615/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148584829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}