Cláudia B Fontan, Vanessa Cristina Mendes Fagundes, Juliana Paulos de Rezende, Luciana C Zattar, Pablo Maricevich, Ana Carolina Rezende Campolina Maricevich
{"title":"The Role of High-Frequency Ultrasound for Preoperative Management of Neck Rejuvenation Surgery.","authors":"Cláudia B Fontan, Vanessa Cristina Mendes Fagundes, Juliana Paulos de Rezende, Luciana C Zattar, Pablo Maricevich, Ana Carolina Rezende Campolina Maricevich","doi":"10.1002/jum.70061","DOIUrl":"https://doi.org/10.1002/jum.70061","url":null,"abstract":"<p><p>Restoration of the esthetic neck contour is a central goal in facial rejuvenation, requiring detailed knowledge of the submental anatomy. High-frequency ultrasound has emerged as a valuable tool, enabling the precise visualization of glands, muscles, fat compartments, and vascular structures. This article presents a standardized protocol based on literature review and clinical experience to optimize ultrasound evaluation of the cervical region. By facilitating the identification of anatomical variations and supporting communication between radiologists and surgeons, this protocol enhances preoperative planning and contributes to the development of safer, more individualized strategies for neck rejuvenation procedures.</p>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145065053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ultrasound Strain Zero-Crossing for Assessing Adult Hypertonic Muscles: A Feasibility Study.","authors":"Jing Gao, Jonathan M Rubin","doi":"10.1002/jum.70059","DOIUrl":"https://doi.org/10.1002/jum.70059","url":null,"abstract":"<p><strong>Objectives: </strong>To assess the feasibility of ultrasound strain zero-crossing (ZC) to assess adult hypertonic muscles.</p><p><strong>Methods: </strong>After receiving Institutional Review Board (IRB) approval and informed consent, we prospectively performed free-hand compression ultrasound strain imaging (USI) on normal and hypertonic upper trapezius muscles (UTM) and subcutaneous tissues using a linear array transducer (10L4, bandwidth 4-10 MHz). Ultrasound data containing tissue deformation and relaxation produced by axial compression and decompression were processed using 2D speckle tracking software. Using the ZC point on the reference strain curve as the reference, we determined a negative ZC if the muscle strain curve returned to zero strain after or at the same time as that of the reference curve. We determined a positive ZC when the muscle strain curve returned to zero strain ahead of the reference curve. Modified Ashworth Scale (MAS) was used to assess muscle tonicity performed by clinicians. The difference in ZC between normal and hypertonic muscles and the diagnostic performance of ZC in determining ≥mild hypertonic muscles were analyzed using a paired t-test and the receiver operating characteristic curve (ROC), respectively.</p><p><strong>Results: </strong>From October 2023 to August 2024, we performed USI on 28 subjects with normal muscles and 56 with hypertonic muscles (38 men and 46 women, mean age: 52 years). The difference in ZC between normal and hypertonic muscles was statistically significant (P < .001). The area under the ROC of ZC for determining ≥mild hypertonic muscles was 0.92.</p><p><strong>Conclusions: </strong>The study results suggest that ultrasound strain ZC is feasible for determining ≥mild hypertonic muscles with good diagnostic performance.</p>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145040559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"High-Frequency Ultrasound in Eccrine Poroma Diagnosis: A Retrospective Analysis of Distinctive Imaging Characteristics.","authors":"Wan-Mei Xu, Jing Wang, Ping-Ping Luo, Jun-Ming Lu, Jian-Feng Liang","doi":"10.1002/jum.70063","DOIUrl":"https://doi.org/10.1002/jum.70063","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to delineate the ultrasonographic characteristics of eccrine poroma (EP), using high-frequency ultrasound (HFUS) to facilitate non-invasive diagnosis and differentiation from other cutaneous lesions.</p><p><strong>Methods: </strong>Retrospective analysis of 15 patients with histopathologically confirmed EP who underwent preoperative HFUS examination (5-18 MHz) between January 2017 and May 2025. Systematic evaluation included morphological assessment, echogenicity characterization, compositional analysis, and vascular assessment using standardized Doppler grading.</p><p><strong>Results: </strong>This study enrolled 15 patients (mean age 56.60 ± 16.90 years) with solitary lesions ranging from 5.5 to 30.2 mm in diameter. Morphologically, 66.7% presented elliptical configurations, with 86.7% demonstrating well-defined margins. Ultrasonographically, 86.7% exhibited heterogeneous hypoechoic patterns with mixed solid-cystic architecture (cystic component <50%), while smaller lesions (13.3%) showed homogeneous hypoechoic characteristics. All cases demonstrated detectable vascular flow: Grade 3 vascularity in 60.0% and Grade 2 in 40.0%.</p><p><strong>Conclusions: </strong>EP demonstrates consistent ultrasonographic features including heterogeneous hypoechoic architecture, well-defined margins, predominantly solid-cystic composition, and robust vascular perfusion. These findings provide the first comprehensive characterization of EP's imaging features, establishing a foundation for integrating HFUS into diagnostic algorithms and enhancing pre-operative assessment accuracy.</p>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145040532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clévio Cezar da Fonseca, Hugo Perazzo, Sandra Wagner Cardoso, Isabel Cristina Ferreira Tavares, Maria Pia Diniz Ribeiro, Rodrigo de Carvalho Moreira, Lara Esteves Coelho, Emília Moreira Jalil, André Miguel Japiassú, Elias Pimentel Gouvêa, Estevão Portela Nunes, Hugo Boechat Andrade, Luciano Barros Gouvêa, Marcel Treptow Ferreira, Pedro Mendes Azambuja-Rodrigues, Ronaldo Ismerio Moreira, Kim Mattos Geraldo, Lucilene Araújo de Freitas, Vinicius Velleda Pacheco, Beatriz Gilda Jegerhorn Grinsztein, Pedro Emmanuel Alvarenga Americano do Brasil
{"title":"Deep Vein Thrombosis in Critically Ill Patients with COVID-19 Pneumonia: Incidence, Wells Score Diagnostic Performance, and Hospital Prognosis.","authors":"Clévio Cezar da Fonseca, Hugo Perazzo, Sandra Wagner Cardoso, Isabel Cristina Ferreira Tavares, Maria Pia Diniz Ribeiro, Rodrigo de Carvalho Moreira, Lara Esteves Coelho, Emília Moreira Jalil, André Miguel Japiassú, Elias Pimentel Gouvêa, Estevão Portela Nunes, Hugo Boechat Andrade, Luciano Barros Gouvêa, Marcel Treptow Ferreira, Pedro Mendes Azambuja-Rodrigues, Ronaldo Ismerio Moreira, Kim Mattos Geraldo, Lucilene Araújo de Freitas, Vinicius Velleda Pacheco, Beatriz Gilda Jegerhorn Grinsztein, Pedro Emmanuel Alvarenga Americano do Brasil","doi":"10.1002/jum.70046","DOIUrl":"https://doi.org/10.1002/jum.70046","url":null,"abstract":"<p><strong>Objectives: </strong>The risk of major venous thromboembolism (VTE) among patients with COVID-19 is high but varies with disease severity. Estimate the incidence of lower extremity deep venous thrombosis (DVT) in critically ill hospitalized patients with COVID-19, validate the Wells score for DVT diagnosis, and determine patients' prognosis.</p><p><strong>Methods: </strong>This was an observational follow-up study in the context of the diagnosis and prognosis of DVT. All patients were hospitalized in the intensive care unit (ICU) of the Evandro Chagas National Institute of Infectious Diseases. Participants with COVID-19 pneumonia were included. Lower-limb Doppler to assess DVT was performed at admission and follow-up. Prognosis outcomes were death, length of stay, need for mechanical ventilation, vasopressor use, and hemodialysis. Wells' score sensitivity and specificity were estimated at admission. Survival curves were estimated for patients with DVT and adjusted for the SAPS 3 score.</p><p><strong>Results: </strong>Between June 2020 and January 2021, 186 patients were included. The DVT incidence was 0.097. A Wells score of 2 or higher had a sensitivity and specificity of 1.00 and 0.94, respectively. Mortality and mechanical ventilation support were higher in participants with DVT. For these outcomes, after SAPS 3 adjustment, participants with DVT had twice the hazard of those without DVT. A web calculator (https://pedrobrasil.shinyapps.io/INDWELL/) is available for predictions.</p><p><strong>Conclusions: </strong>One can use the Wells score to accurately diagnose DVT in critically ill patients with COVID-19. DVT increases the severity of COVID-19, which highlights the importance of its early diagnosis, treatment, and prophylaxis in the ICU setting.</p>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145030078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
John Kim, David Lee, Michael Schwartz, Tanping Wong, Kevin Piro, James C Hudspeth, Lao-Tzu Allan-Blitz
{"title":"Point-of-Care Ultrasound in Hospital Medicine: A Narrative Review.","authors":"John Kim, David Lee, Michael Schwartz, Tanping Wong, Kevin Piro, James C Hudspeth, Lao-Tzu Allan-Blitz","doi":"10.1002/jum.70050","DOIUrl":"https://doi.org/10.1002/jum.70050","url":null,"abstract":"","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145015615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chen Cheng, Xiao Peng, Keke Sang, Hongyan Zhao, Di Wu, Honge Li, Yan Wang, Wenrong Wang, Feng Xu, Jine Zhao
{"title":"Prognostic Utility of a Deep Learning Radiomics Nomogram Integrating Ultrasound and Multi-Sequence MRI in Triple-Negative Breast Cancer Treated with Neoadjuvant Chemotherapy.","authors":"Chen Cheng, Xiao Peng, Keke Sang, Hongyan Zhao, Di Wu, Honge Li, Yan Wang, Wenrong Wang, Feng Xu, Jine Zhao","doi":"10.1002/jum.70054","DOIUrl":"https://doi.org/10.1002/jum.70054","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study is to evaluate the prognostic performance of a nomogram integrating clinical parameters with deep learning radiomics (DLRN) features derived from ultrasound and multi-sequence magnetic resonance imaging (MRI) for predicting survival, recurrence, and metastasis in patients diagnosed with triple-negative breast cancer (TNBC) undergoing neoadjuvant chemotherapy (NAC).</p><p><strong>Methods: </strong>This retrospective, multicenter study included 103 patients with histopathologically confirmed TNBC across four institutions. The training group comprised 72 cases from the First People's Hospital of Lianyungang, while the validation group included 31 cases from three external centers. Clinical and follow-up data were collected to assess prognostic outcomes. Radiomics features were extracted from two-dimensional ultrasound and three-dimensional MRI images following image segmentation. A DLRN model was developed, and its prognostic performance was evaluated using the concordance index (C-index) in comparison with alternative modeling approaches. Risk stratification for postoperative recurrence was subsequently performed, and recurrence and metastasis rates were compared between low- and high-risk groups.</p><p><strong>Results: </strong>The DLRN model demonstrated strong predictive capability for DFS (C-index: 0.859-0.887) and moderate performance for overall survival (OS) (C-index: 0.800-0.811). For DFS prediction, the DLRN model outperformed other models, whereas its performance in predicting OS was slightly lower than that of the combined MRI + US radiomics model. The 3-year recurrence and metastasis rates were significantly lower in the low-risk group than in the high-risk group (21.43-35.71% vs 77.27-82.35%).</p><p><strong>Conclusion: </strong>The preoperative DLRN model, integrating ultrasound and multi-sequence MRI, shows promise as a prognostic tool for recurrence, metastasis, and survival outcomes in patients with TNBC undergoing NAC. The derived risk score may facilitate individualized prognostic evaluation and aid in preoperative risk stratification within clinical settings.</p>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145015633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Reem S Abu-Rustum, Erica Smith, Kam Szlachetka, Oxana M Zarudskaya
{"title":"A Practical Approach to Incorporating the Detailed First Trimester Ultrasound Examination into Clinical Practice.","authors":"Reem S Abu-Rustum, Erica Smith, Kam Szlachetka, Oxana M Zarudskaya","doi":"10.1002/jum.70044","DOIUrl":"https://doi.org/10.1002/jum.70044","url":null,"abstract":"<p><p>Tremendous advances in ultrasound equipment and knowledge have expanded possibilities for the first trimester detailed ultrasound examination. Recommendations from national organizations to offer this service to patients with indications, coupled with recent modifications for dual use of the current procedural terminology code 76811 during pregnancy, will result in increased demand from patients and referring physicians. While proper reimbursement may motivate healthcare professionals to incorporate the first trimester detailed ultrasound examination into their practice and raise the standards of care in the first trimester, it can also be a challenging transition. In this article, we present a practical approach and share tips and pearls on how to incorporate the first trimester detailed ultrasound into clinical practice.</p>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145015687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prenatal Diagnosis of Atretic Cephalocele: Ultrasound Demonstration of Superior Sagittal Sinus Fenestration and Fibrous Stalk, and Potential Role of Brainstem-Tentorium Angle.","authors":"Deepak Bansal, Aastha B Chawla, Palavi Singla","doi":"10.1002/jum.70058","DOIUrl":"https://doi.org/10.1002/jum.70058","url":null,"abstract":"<p><p>We present two cases highlighting novel prenatal ultrasound findings in atretic cephalocele (AC) using high-resolution ultrasound and microvascular flow imaging. This report includes the first prenatal ultrasound demonstration of key diagnostic AC features: superior sagittal sinus fenestration, observed in the parietal case, and a fibrous dural stalk, identified in both parietal and occipital cases. Both fetuses presented with a small midline scalp lesion, internal echoes, and an underlying bony defect without brain tissue herniation. Additionally, an increased brainstem-tentorium angle was measured in both, suggesting its potential utility as a supportive diagnostic marker. We propose a refined two-tiered diagnostic framework to improve the accuracy of prenatal AC diagnosis and distinguish AC from true encephaloceles, facilitating appropriate parental counseling.</p>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145015664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ultrasonography Combined With Strain Elastography for Differentiation of Parotid Masses: Methodological Considerations and Advanced Imaging Perspectives.","authors":"Enes Gurun","doi":"10.1002/jum.70060","DOIUrl":"https://doi.org/10.1002/jum.70060","url":null,"abstract":"","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145015674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Karine S Da Correggio, Luís Otávio Santos, Felipe S Muylaert Barroso, Roberto N Galluzzo, Thiago Z L Chaves, Aldo von Wangenheim, Alexandre S C Onofre
{"title":"AI-Driven Fetal Liver Echotexture Analysis: A New Frontier in Predicting Neonatal Insulin Imbalance.","authors":"Karine S Da Correggio, Luís Otávio Santos, Felipe S Muylaert Barroso, Roberto N Galluzzo, Thiago Z L Chaves, Aldo von Wangenheim, Alexandre S C Onofre","doi":"10.1002/jum.70053","DOIUrl":"https://doi.org/10.1002/jum.70053","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the performance of artificial intelligence (AI)-based models in predicting elevated neonatal insulin levels through fetal hepatic echotexture analysis.</p><p><strong>Methods: </strong>This diagnostic accuracy study analyzed ultrasound images of fetal livers from pregnancies between 37 and 42 weeks, including cases with and without gestational diabetes mellitus (GDM). Images were stored in Digital Imaging and Communications in Medicine (DICOM) format, annotated by experts, and converted to segmented masks after quality checks. A balanced dataset was created by randomly excluding overrepresented categories. Artificial intelligence classification models developed using the FastAI library-ResNet-18, ResNet-34, ResNet-50, EfficientNet-B0, and EfficientNet-B7-were trained to detect elevated C-peptide levels (>75th percentile) in umbilical cord blood at birth, based on fetal hepatic ultrasonographic images.</p><p><strong>Results: </strong>Out of 2339 ultrasound images, 606 were excluded due to poor quality, resulting in 1733 images analyzed. Elevated C-peptide levels were observed in 34.3% of neonates. Among the 5 CNN models evaluated, EfficientNet-B0 demonstrated the highest overall performance, achieving a sensitivity of 86.5%, specificity of 82.1%, positive predictive value (PPV) of 83.0%, negative predictive value (NPV) of 85.7%, accuracy of 84.3%, and an area under the ROC curve (AUC) of 0.83 in predicting elevated neonatal insulin levels through fetal hepatic echotexture analysis.</p><p><strong>Conclusion: </strong>AI-based analysis of fetal liver echotexture via ultrasound effectively predicted elevated neonatal C-peptide levels, offering a promising non-invasive method for detecting insulin imbalance in newborns.</p>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145015628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}