Priscila Giavedoni, Said Fallas, Laura Serra, Teresa Torres, Pau Rosés-Gibert, Irene Fuertes de Vega, Asunción Vicente, Ximena Wortsman, Cristina Carrera
{"title":"The Usefulness of High-Frequency Ultrasound in the Management of Patients with Giant Congenital Melanocytic Nevi: A Cohort Prospective Study.","authors":"Priscila Giavedoni, Said Fallas, Laura Serra, Teresa Torres, Pau Rosés-Gibert, Irene Fuertes de Vega, Asunción Vicente, Ximena Wortsman, Cristina Carrera","doi":"10.1002/jum.16684","DOIUrl":"https://doi.org/10.1002/jum.16684","url":null,"abstract":"<p><strong>Objectives: </strong>Congenital melanocytic nevi (CMN) exhibit various clinical presentations. Dermoscopy and confocal microscopy only assess the superficial dermis. Magnetic resonance imaging cannot evaluate skin layers comprehensively. High-frequency Doppler ultrasound (HFUS) can define the extent of melanocytic lesions and suggest patterns of potential complications. The objective of the study is to evaluate HFUS characteristics of patients with CMN and, secondarily, to study the utility of HFUS in evaluating proliferative nodules and enlarged lymph nodes.</p><p><strong>Methods: </strong>A prospective study of patients with multiple and non-small CMN between January 2016 and June 2021 was conducted. Clinical imaging and HFUS were routinely used to follow up on distinctive areas. A retrospective analysis of HFUS images and correlation with presentation was performed.</p><p><strong>Results: </strong>Seventy-one patients with CMN, 149 HFUS scans. Median age: 14 years (IQR: 8 months-79 years), 59% female. Large/giant nevi n = 44 (61.9%). CMN affected the epidermis/dermis in 51 (71.8%), hypodermis in 17 (24%), and muscle in 3 (4.2%). Thirteen patients (18.3%) had nodular lesions; 1 showed atypical vessels on HFUS, which was confirmed histologically as an atypical proliferative nodule.</p><p><strong>Limitations: </strong>Heterogeneity of patients and retrospective analysis.</p><p><strong>Conclusions: </strong>HFUS allows the characterization of non-small CMN by assessing depth and diagnosing complications such as melanomas and enlarged lymph nodes.</p>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143663842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Revisiting Ultrasound of Fetal Abdominal Cysts; the Common, the Uncommon and the Rare: A Pictorial Review.","authors":"Bhumika Singh, Durr E Sabih, Bronshtein Moshe, Azer Ferec, Dong Nguyen, Lilit Hovsepyan, Yaron Zalel","doi":"10.1002/jum.16678","DOIUrl":"https://doi.org/10.1002/jum.16678","url":null,"abstract":"<p><p>Fetal abdominal cysts are rare. The significance of antenatally discovered abdominal cysts can range from an innocuous finding to serious conditions needing surgery. It is often difficult to arrive at a correct diagnosis based on ultrasonography, as different types of cysts can have similar appearances. A more specific diagnosis is possible if fetal sex, age at appearance, location of the cyst, shape and appearance of the walls, and contents are considered. This review presents an extensive spectrum of fetal abdominal cysts. The common as well as the very rare causes that have only a few reports are discussed. Ultrasound images of confirmed cases are also presented. An algorithmic approach that enables a more specific diagnosis in many cases has been developed.</p>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143657616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Backscatter Anisotropy in Assessing Hepatic Steatosis Using Ultrasound Hepatorenal Index: Comment.","authors":"Hinpetch Daungsupawong, Viroj Wiwanitkit","doi":"10.1002/jum.16685","DOIUrl":"https://doi.org/10.1002/jum.16685","url":null,"abstract":"","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143657614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ashley Shea, Ashley N Battarbee, Katherine L Grantz, Dian He, John Owen
{"title":"Expanding the Estimated Fetal Weight Definition of Growth Restriction by Adding Small Abdominal Circumference: Prediction of Neonatal Morbidity.","authors":"Ashley Shea, Ashley N Battarbee, Katherine L Grantz, Dian He, John Owen","doi":"10.1002/jum.16683","DOIUrl":"https://doi.org/10.1002/jum.16683","url":null,"abstract":"<p><strong>Objective: </strong>The Society for Maternal-Fetal Medicine's (SMFM) diagnostic criteria for fetal growth restriction (FGR) recently added abdominal circumference (AC) <10th percentile to estimated fetal weight (EFW) <10th percentile; however, its prediction of neonatal morbidity is unknown. Our objective was to compare the two definitions for their prediction of composite neonatal morbidity.</p><p><strong>Methods: </strong>Secondary analysis of the Fetal Growth Study-Singletons, 2009-2013. The last ultrasound (mean 36.9 ± 2.3 weeks) was included from non-anomalous fetuses. Composite neonatal morbidity was the primary outcome: metabolic acidosis, neonatal intensive care unit stay >3 days, significant respiratory morbidities, seizures, hyperbilirubinemia requiring exchange transfusion, intrapartum aspiration, necrotizing enterocolitis, hypoglycemia, hypoxic ischemic encephalopathy, periventricular leukomalacia, sepsis, retinopathy of prematurity, or neonatal death. The secondary outcome was small for gestational age (SGA). Logistic regression modeled the association of each FGR definition with outcomes, and receiver operating characteristic area under the curve (AUC) assessed predictive ability.</p><p><strong>Results: </strong>Of 2400 eligible individuals, 135 (5.6%) neonates had composite neonatal morbidity, and 245 (10%) were SGA. At the last ultrasound, 181 (7.5%) had FGR based on EFW alone (original definition) and 215 (9.0%) had FGR based on a small EFW or AC (expanded definition) (P < .0001). Both definitions had poor discrimination for composite neonatal morbidity (original: AUC 0.52, 95% confidence interval [CI] 0.49-0.54; expanded: AUC 0.51, 95% CI, 0.48-0.54). Both had acceptable discrimination of SGA (original: AUC 0.70, 95% CI 0.67-0.73; expanded: AUC 0.71, 95% CI 0.68-0.75).</p><p><strong>Conclusions: </strong>Adding AC <10th percentile to the EFW <10th percentile definition of FGR significantly increased the incidence of FGR but did not improve the prediction of neonatal morbidity in a low-risk population. The SMFM guideline for FGR should be adopted with caution.</p>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143657615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kourosh Kalayeh, J Brian Fowlkes, Bryan S Sack, Jennifer LaCross, Stephanie Daignault-Newton, Payton Schmidt, Haowei Tai, William W Schultz, James A Ashton-Miller, John O DeLancey
{"title":"A New Automated Ultrasound Quantification of Urethral Mobility for Stress Urinary Incontinence: A Feasibility Study.","authors":"Kourosh Kalayeh, J Brian Fowlkes, Bryan S Sack, Jennifer LaCross, Stephanie Daignault-Newton, Payton Schmidt, Haowei Tai, William W Schultz, James A Ashton-Miller, John O DeLancey","doi":"10.1002/jum.16676","DOIUrl":"https://doi.org/10.1002/jum.16676","url":null,"abstract":"<p><strong>Objectives: </strong>Stress urinary incontinence (SUI) is a prevalent condition that can significantly affect quality of life. Urethral mobility is an important factor in SUI and transperineal ultrasound (TPUS) imaging can provide clear visualization of this movement; however, its quantification has been limited. An automated system to track and quantify urethral movement could provide richer information and reduce inter-observer effects on measurements.</p><p><strong>Methods: </strong>As proof-of-concept for technique development, we used TPUS cine loops obtained on commercial scanners (GE Healthcare and Philips Healthcare) from consented research volunteers. We developed the tracking software based on fundamental concepts from computer vision, specifically corner detection and optical flow-based tracking algorithms. In doing so we account for inadvertent probe movements by using the symphysis pubis as a reference coordinate system.</p><p><strong>Results: </strong>The system successfully tracks the motion of the urethra during Valsalva maneuvers. It accurately captures and quantifies complex movements, including directional shifts, rotations, displacement vectors of different structures, and the trajectory of motion. These measurements are corrected for any probe movement. We demonstrated the system's efficiency and reliability in near real-time analysis across various ultrasound platforms and video formats. The intraclass correlation coefficients exceeded 0.89 and 0.5 for intra- and inter-rater reliability, respectively.</p><p><strong>Conclusions: </strong>By providing detailed, objective measurements of urogenital movement, this approach has potential to advance the understanding, diagnosis and treatment of SUI, which in turn, can help tailor more effective treatment strategies. This methodology paper confirms the feasibility of automated quantification of urethral mobility.</p>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Advancements in Three-Dimensional Super-Resolution Ultrasound Imaging: A Narrative Review.","authors":"Debabrata Ghosh, Kenneth Hoyt","doi":"10.1002/jum.16682","DOIUrl":"10.1002/jum.16682","url":null,"abstract":"<p><p>The lack of sensibility of traditional ultrasound (US) imaging to the slow blood flow in small vessels resulted in the development of microbubble (MB) contrast agents. These MBs are given intravenously, and US imaging can detect them quite effectively. This noninvasive imaging method, known as contrast-enhanced US (CEUS), now makes it possible to accurately assess tissue perfusion and blood flow. Though CEUS offers several benefits, diffraction restricts the spatial resolution of all US imaging systems to length scales equal to roughly half the wavelength of the transmitted US beam. Based on individual MB detection and localization, the recently developed super-resolution US (SRUS) imaging method has shown unprecedentedly high spatial resolution exceeding the physical diffraction limit. It is now possible to visualize the microvasculature beyond the diffraction-limited resolution by localizing spatially isolated MBs across several frames. The highest resolution possible at clinical US frequencies can be on the order of several micrometers when tissue and probe motion are not present. Enhancing the functional study of tissue microvascular networks with structural data could lead to improved disease management. Through the localization and tracking of MBs, SRUS may reconstruct images of the microvasculature with resolution exceeding the diffraction limit in both 2-dimensional (2D) and 3-dimensional (3D) space. In contrast to the 2D approach, 3D SRUS imaging does not suffer from out-of-plane motion and can offer volumetric coverage with super-resolution in all three dimensions. Research has used two primary methods for 3D SRUS imaging including arrays that can electronically gather volumetric information or mechanically scanning the volume with a linear probe to produce a stack of 2D SRUS images. This manuscript aims to offer a comprehensive review of 3D SRUS imaging, clarifying methodologies, clinical applications, and notable challenges that could motivate future research and help facilitate clinical translation.</p>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143605353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yordan Hristov Georgiev, Bianca Haase, Felix Neunhoeffer, Johannes Nordmeyer, Ilias Tsiflikas, Jörg Michel, Maximilian Gross
{"title":"The Utility of Lung Ultrasound Scoring in Predicting Post-Extubation Respiratory Support after Congenital Heart Surgery.","authors":"Yordan Hristov Georgiev, Bianca Haase, Felix Neunhoeffer, Johannes Nordmeyer, Ilias Tsiflikas, Jörg Michel, Maximilian Gross","doi":"10.1002/jum.16668","DOIUrl":"https://doi.org/10.1002/jum.16668","url":null,"abstract":"<p><strong>Objectives: </strong>Lung ultrasound (LU) is effective in diagnosing the accumulation of extravascular lung water and assessing real-time fluid status in infants following congenital cardiac surgery with cardiopulmonary bypass. This study evaluated whether LU can be used as a prognostic marker for changes in noninvasive respiratory support after extubation.</p><p><strong>Methods: </strong>Infants with congenital heart disease (CHD) <1 year of age requiring mechanical ventilation for more than 24 hours postoperatively were included. Using a linear probe, 3 scan fields from each hemithorax were assessed for B-lines and consolidations, with scores ranging from 0 to 3 assigned per area. LU scores were rated then by 4 independent operators. After extubation, patients were monitored for respiratory support modifications over the following 48 hours and were divided into 3 subgroups: steady state, escalation, and de-escalation, accordingly.</p><p><strong>Results: </strong>In this single-center observational pilot study, a total of 30 patients with a median age of 116 (interquartile range: 17-196) days were included in the prospective analysis between July 2022 and December 2023. LU scores differed significantly among groups: 3.47 ± 2.3 (steady state), 6.14 ± 2.55 (escalation), and 1.63 ± 1.41 (de-escalation), P = .002. ROC analysis identified a cut-off score of ≥5 as predictive of escalation risk with a sensitivity of 86% and specificity of 83%. A score <2 suggested potential for de-escalation within 48 hours, with a sensitivity of 75% and specificity of 73%.</p><p><strong>Conclusions: </strong>LU scoring may be a valuable tool for optimizing ventilator weaning and post-extubation respiratory strategies in infants undergoing congenital cardiac surgery. Further studies are warranted to validate these findings.</p>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143586208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Refining the Accuracy of Pelvic Free Fluid Estimation in Pediatric Trauma: Insights on Physician Performance in FAST Imaging.","authors":"Liying Zheng","doi":"10.1002/jum.16677","DOIUrl":"https://doi.org/10.1002/jum.16677","url":null,"abstract":"","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143573312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Web-Based Deliberate Practice of Pediatric Point of Care Ultrasound Cases in Resource-Limited Settings: A Multicenter Implementation and Effectiveness Study.","authors":"Angelo Ricci, Daniel Lindsay, Carla Schwanfelder, Erin Stratta, Michelle Lee, Kathy Boutis","doi":"10.1002/jum.16679","DOIUrl":"https://doi.org/10.1002/jum.16679","url":null,"abstract":"<p><strong>Objectives: </strong>The main objective of this study was to implement an online pediatric case-based POCUS course in low-resource medical settings and examine learning outcomes and feasibility.</p><p><strong>Methods: </strong>This was a multicenter prospective cohort study conducted in a convenience sample of clinicians affiliated with Médecins Sans Frontières (MSF) training sites. MSF POCUS trainers provided the standard hands-on, on-site POCUS training and supplemented this with access to a web-based course. Participants provided diagnoses for 400 image-based POCUS cases from four common pediatric POCUS applications until they achieved the mastery learning standard of 90% accuracy, sensitivity (cases with pathology), and specificity (cases without pathology). Each participant also completed a course evaluation.</p><p><strong>Results: </strong>From 10 MSF sites, 110 clinicians completed 82,206 cases. There were significant learning gains across the POCUS applications with respect to accuracy (delta 14.2%; 95% CI 13.1, 15.2), sensitivity (delta 13.2%; 95% CI 12.1, 14.2), and specificity (delta 13.8%; 95% CI 12.7, 15.0). Furthermore, 90 (81.8%) achieved the mastery learning standard in at least one application, and 69 (62.7%) completed a course evaluation on at least one application for a total of 231 evaluations. Of these, 206 (89.2%) agreed/strongly agreed that the experience had relevance to their practice, met expectations, and had a positive user design. However, 59/110 (53.6%) clinicians reported a lack of protected time, and 54/110 (49.0%) identified challenges with accessing internet/hardware.</p><p><strong>Conclusions: </strong>In resource-limited MSF settings, implementing web-based POCUS case practice demonstrated successful learning outcomes despite approximately half of the participants encountering significant technical challenges.</p>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143573317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}