Priscila Giavedoni, Florencia Vera-Morandini, Irene Fuertes de Vega, Andrea Combalia, Carolina Fernández-Quiroga, Sebastián Podlipnik, Ximena Wortsman
{"title":"额部纤维性脱发高频超声亚临床表现的横断面分析。","authors":"Priscila Giavedoni, Florencia Vera-Morandini, Irene Fuertes de Vega, Andrea Combalia, Carolina Fernández-Quiroga, Sebastián Podlipnik, Ximena Wortsman","doi":"10.1002/jum.16751","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>Frontal fibrosing alopecia (FFA) has a progressive course; quantifying changes at each visit can be complex. High-frequency ultrasound (HFUS) has been used to assess hair follicle morphology and scalp vascularization. The objectives of the study are to evaluate HFUS characteristics of patients with FFA and, secondarily, to study the usefulness of HFUS in assessing disease activity.</p><p><strong>Methods: </strong>Prospective study between January and June 2018. Patients with confirmed FFA were included. A retrospective analysis of HFUS imaging and its correlation with clinical presentation was performed.</p><p><strong>Results: </strong>Fifteen AFF female patients (median age: 65 years) met the study criteria. A total of 75 ultrasound images were analyzed. The atrophic region exhibited significant dermis thinning (0.7 mm; 0.3-1.2 mm range) compared to healthy sites. Frontal hair growth area showed reduced follicle number and miniaturization. HFUS Doppler ultrasound identified subclinical inflammation in 26.6% of patients.</p><p><strong>Conclusions: </strong>HFUS allows the characterization of FFA by quantitatively assessing dermal atrophy and the miniaturization and shrinkage of hair follicles. In addition, it allows the diagnosis of subclinical inflammation.</p>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.4000,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Cross-Sectional Analysis of Subclinical Findings Using High-Frequency Ultrasound in Frontal Fibrosing Alopecia.\",\"authors\":\"Priscila Giavedoni, Florencia Vera-Morandini, Irene Fuertes de Vega, Andrea Combalia, Carolina Fernández-Quiroga, Sebastián Podlipnik, Ximena Wortsman\",\"doi\":\"10.1002/jum.16751\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objectives: </strong>Frontal fibrosing alopecia (FFA) has a progressive course; quantifying changes at each visit can be complex. High-frequency ultrasound (HFUS) has been used to assess hair follicle morphology and scalp vascularization. The objectives of the study are to evaluate HFUS characteristics of patients with FFA and, secondarily, to study the usefulness of HFUS in assessing disease activity.</p><p><strong>Methods: </strong>Prospective study between January and June 2018. Patients with confirmed FFA were included. A retrospective analysis of HFUS imaging and its correlation with clinical presentation was performed.</p><p><strong>Results: </strong>Fifteen AFF female patients (median age: 65 years) met the study criteria. A total of 75 ultrasound images were analyzed. The atrophic region exhibited significant dermis thinning (0.7 mm; 0.3-1.2 mm range) compared to healthy sites. Frontal hair growth area showed reduced follicle number and miniaturization. HFUS Doppler ultrasound identified subclinical inflammation in 26.6% of patients.</p><p><strong>Conclusions: </strong>HFUS allows the characterization of FFA by quantitatively assessing dermal atrophy and the miniaturization and shrinkage of hair follicles. In addition, it allows the diagnosis of subclinical inflammation.</p>\",\"PeriodicalId\":17563,\"journal\":{\"name\":\"Journal of Ultrasound in Medicine\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":2.4000,\"publicationDate\":\"2025-06-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Ultrasound in Medicine\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1002/jum.16751\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"ACOUSTICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Ultrasound in Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1002/jum.16751","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ACOUSTICS","Score":null,"Total":0}
Cross-Sectional Analysis of Subclinical Findings Using High-Frequency Ultrasound in Frontal Fibrosing Alopecia.
Objectives: Frontal fibrosing alopecia (FFA) has a progressive course; quantifying changes at each visit can be complex. High-frequency ultrasound (HFUS) has been used to assess hair follicle morphology and scalp vascularization. The objectives of the study are to evaluate HFUS characteristics of patients with FFA and, secondarily, to study the usefulness of HFUS in assessing disease activity.
Methods: Prospective study between January and June 2018. Patients with confirmed FFA were included. A retrospective analysis of HFUS imaging and its correlation with clinical presentation was performed.
Results: Fifteen AFF female patients (median age: 65 years) met the study criteria. A total of 75 ultrasound images were analyzed. The atrophic region exhibited significant dermis thinning (0.7 mm; 0.3-1.2 mm range) compared to healthy sites. Frontal hair growth area showed reduced follicle number and miniaturization. HFUS Doppler ultrasound identified subclinical inflammation in 26.6% of patients.
Conclusions: HFUS allows the characterization of FFA by quantitatively assessing dermal atrophy and the miniaturization and shrinkage of hair follicles. In addition, it allows the diagnosis of subclinical inflammation.
期刊介绍：
The Journal of Ultrasound in Medicine (JUM) is dedicated to the rapid, accurate publication of original articles dealing with all aspects of medical ultrasound, particularly its direct application to patient care but also relevant basic science, advances in instrumentation, and biological effects. The journal is an official publication of the American Institute of Ultrasound in Medicine and publishes articles in a variety of categories, including Original Research papers, Review Articles, Pictorial Essays, Technical Innovations, Case Series, Letters to the Editor, and more, from an international bevy of countries in a continual effort to showcase and promote advances in the ultrasound community.
Represented through these efforts are a wide variety of disciplines of ultrasound, including, but not limited to:
-Basic Science-
Breast Ultrasound-
Contrast-Enhanced Ultrasound-
Dermatology-
Echocardiography-
Elastography-
Emergency Medicine-
Fetal Echocardiography-
Gastrointestinal Ultrasound-
General and Abdominal Ultrasound-
Genitourinary Ultrasound-
Gynecologic Ultrasound-
Head and Neck Ultrasound-
High Frequency Clinical and Preclinical Imaging-
Interventional-Intraoperative Ultrasound-
Musculoskeletal Ultrasound-
Neurosonology-
Obstetric Ultrasound-
Ophthalmologic Ultrasound-
Pediatric Ultrasound-
Point-of-Care Ultrasound-
Public Policy-
Superficial Structures-
Therapeutic Ultrasound-
Ultrasound Education-
Ultrasound in Global Health-
Urologic Ultrasound-
Vascular Ultrasound
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