Journal of Ultrasound in Medicine最新文献

{"title":"Feasibility Analysis of Ultra-Resolution Microscopy Based on Contrast-Enhanced Ultrasound (CEUS) in Benign and Malignant Breast Lesions.","authors":"Peng-Fei Sun, Li-Xue Zhai, Yun-Yun Dong, Xiang-Dong Hu, Min Li, Lin-Xue Qian, Jun-Feng Zhao","doi":"10.1002/jum.16699","DOIUrl":"https://doi.org/10.1002/jum.16699","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the diagnostic value of quantitative analysis using ultra-resolution microscopy (URM) in differentiating benign from malignant breast lesions.</p><p><strong>Material and methods: </strong>This prospective study enrolled 60 patients with 60 breast lesions who underwent contrast-enhanced ultrasound (CEUS) using SonoVue (Bracco Imaging, Italy) between June 2024 and August 2024. Quantitative parameters of microvascular density and velocity maps were generated for the lesion interior, rim region, and combined interior and rim area using URM software on CEUS images. The parameters were analyzed for differences between benign and malignant breast lesions, and their diagnostic efficacy was evaluated.</p><p><strong>Results: </strong>Multivariate analysis indicated that breast malignancy was associated with microvascular ratio and complexity level. The area under the curve (AUC) for the combined diagnostic method that included microvascular parameters at the lesion margin (Rim group) and BI-RADS classification + Rim was higher than other diagnostic approaches (AUC = 0.92), although there was no significant difference when compared with the combined approach of evaluating parameters within the lesion and at the margin alongside BI-RADS (Mass + Rim + BI-RADS group, P = .293). The BI-RADS group showed high sensitivity (100%) and negative predictive value (100%); the Mass group (parameters within the lesion) demonstrated higher sensitivity (87.0%), and the Rim group (parameters at the lesion margin) exhibited the highest specificity (91.9%).</p><p><strong>Conclusion: </strong>URM shows potential in distinguishing between benign and malignant breast lesions, offering a precise assessment of lesion hemodynamics and providing valuable information for clinical diagnosis and treatment.</p>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143811622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prospective Observational Study of Emergency Department Point-of-Care Ultrasound to Differentiate Between Complicated and Uncomplicated Appendicitis.","authors":"Almaz S Dessie, Maria Kwok, Lisa Mills, Adam Sivitz, Marsha Elkhunovich, Benjamin Nti, Erika Constantine, Kelly Bergmann, Atim Ekpenyong, Amanda Toney, Xiaoyang Li, Peter S Dayan, David Kessler","doi":"10.1002/jum.16702","DOIUrl":"https://doi.org/10.1002/jum.16702","url":null,"abstract":"<p><strong>Objectives: </strong>Acute appendicitis is a common surgical emergency in children. Prior radiology studies have described Puylaert staging on ultrasound to determine the severity of appendicitis. We investigated the feasibility and utility of assessing Puylaert staging on emergency department (ED) point-of-care ultrasound (POCUS) to differentiate uncomplicated from complicated appendicitis in children.</p><p><strong>Methods: </strong>This was a pilot feasibility study of children ages 5-17 diagnosed with acute appendicitis in nine pediatric EDs. POCUS was performed by trained ED physicians. Puylaert staging of the submucosal layer was used to categorize the severity of appendicitis (stages 1-4) and was compared with surgical pathology reports. Test characteristics were computed to evaluate the accuracy of POCUS in differentiating appendicitis severity. Physicians recorded time to complete POCUS, ease of use, and their perception of acceptability by patients and families.</p><p><strong>Results: </strong>Of 72 patients with complete data, all patients with uncomplicated appendicitis were accurately identified using POCUS (Puylaert stage 1 or 2). The sensitivity for identifying complicated appendicitis (Puylaert Stage 3 or 4) was 100% (95% CI: 77%-100%), and specificity was 65% (95% CI: 52%-78%). Ninety four percent of physicians agreed that the POCUS was easy to perform. One hundred percent agreed that it was well accepted by families. The average time to complete POCUS was 8 min.</p><p><strong>Conclusions: </strong>This study supports the feasibility and utility of assessing Puylaert staging by POCUS for children with appendicitis in the ED. High sensitivity to rule out complicated cases coupled with ease of use and perceived patient acceptance make this a potential adjunct to aid in the management of pediatric appendicitis.</p>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143811623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantitative Dynamic Contrast-Enhanced Ultrasound Confirms Renal Obstruction: A Feasibility Study.","authors":"Kourosh Kalayeh, Sapan N Ambani, Man Zhang, Stephanie Daignault-Newton, Benjamin L Viglianti, Rashmi Mediratta, William W Schultz, J Brian Fowlkes, Bryan S Sack","doi":"10.1002/jum.16698","DOIUrl":"https://doi.org/10.1002/jum.16698","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objectives: &lt;/strong&gt;To evaluate dynamic contrast-enhanced ultrasound (DCEUS) potential for diagnosing ureteropelvic junction obstruction (UPJO). We hypothesize that DCEUS can identify differences in renal parenchymal microcirculation between normal and obstructed kidneys.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Materials and methods: &lt;/strong&gt;This prospective study included 8 subjects (16 kidneys) with unilateral renal obstruction clinically determined to need surgery and confirmed by nuclear medicine (NM) diuretic half-time ( &lt;math&gt; &lt;semantics&gt; &lt;mrow&gt;&lt;msub&gt;&lt;mi&gt;t&lt;/mi&gt; &lt;mrow&gt;&lt;mn&gt;1&lt;/mn&gt; &lt;mo&gt;/&lt;/mo&gt; &lt;mn&gt;2&lt;/mn&gt;&lt;/mrow&gt; &lt;/msub&gt; &lt;mo&gt;≥&lt;/mo&gt; &lt;mn&gt;20&lt;/mn&gt; &lt;mspace&gt;&lt;/mspace&gt; &lt;mi&gt;min&lt;/mi&gt;&lt;/mrow&gt; &lt;annotation&gt;$$ {t}_{1/2}ge 20kern0.5em min $$&lt;/annotation&gt;&lt;/semantics&gt; &lt;/math&gt; ). Subjects underwent pre- and post-surgery DCEUS and NM imaging at a tertiary care institution (Dec 2021 to Oct 2024). DCEUS-derived time-intensity curves were analyzed to calculate mean-transit time (MTT), time-to-peak (TTP), and full-width at half-maximum (FWHM). DCEUS MTT was compared between normal and affected kidneys and to NM &lt;math&gt; &lt;semantics&gt; &lt;mrow&gt;&lt;msub&gt;&lt;mi&gt;t&lt;/mi&gt; &lt;mrow&gt;&lt;mn&gt;1&lt;/mn&gt; &lt;mo&gt;/&lt;/mo&gt; &lt;mn&gt;2&lt;/mn&gt;&lt;/mrow&gt; &lt;/msub&gt; &lt;/mrow&gt; &lt;annotation&gt;$$ {t}_{1/2} $$&lt;/annotation&gt;&lt;/semantics&gt; &lt;/math&gt; . Statistical significance was determined using two-sided paired and unpaired Student t-tests.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;MTT was significantly longer in obstructed kidneys compared to normal kidneys before surgery ( &lt;math&gt; &lt;semantics&gt;&lt;mrow&gt;&lt;mn&gt;52&lt;/mn&gt; &lt;mo&gt;±&lt;/mo&gt; &lt;mn&gt;7&lt;/mn&gt; &lt;mspace&gt;&lt;/mspace&gt; &lt;mi&gt;s&lt;/mi&gt;&lt;/mrow&gt; &lt;annotation&gt;$$ 52pm 7kern0.22em mathrm{s} $$&lt;/annotation&gt;&lt;/semantics&gt; &lt;/math&gt; vs. &lt;math&gt; &lt;semantics&gt;&lt;mrow&gt;&lt;mn&gt;18&lt;/mn&gt; &lt;mo&gt;±&lt;/mo&gt; &lt;mn&gt;3&lt;/mn&gt; &lt;mspace&gt;&lt;/mspace&gt; &lt;mi&gt;s&lt;/mi&gt; &lt;mo&gt;;&lt;/mo&gt; &lt;mspace&gt;&lt;/mspace&gt; &lt;mi&gt;P&lt;/mi&gt; &lt;mo&gt;=&lt;/mo&gt; &lt;mn&gt;.002&lt;/mn&gt;&lt;/mrow&gt; &lt;annotation&gt;$$ 18pm 3kern0.22em mathrm{s};kern0.5em P=.002 $$&lt;/annotation&gt;&lt;/semantics&gt; &lt;/math&gt; ) and normalized after pyeloplasty ( &lt;math&gt; &lt;semantics&gt;&lt;mrow&gt;&lt;mn&gt;13&lt;/mn&gt; &lt;mo&gt;±&lt;/mo&gt; &lt;mn&gt;3&lt;/mn&gt; &lt;mspace&gt;&lt;/mspace&gt; &lt;mi&gt;s&lt;/mi&gt;&lt;/mrow&gt; &lt;annotation&gt;$$ 13pm 3;mathrm{s} $$&lt;/annotation&gt;&lt;/semantics&gt; &lt;/math&gt; vs. &lt;math&gt; &lt;semantics&gt;&lt;mrow&gt;&lt;mn&gt;14&lt;/mn&gt; &lt;mo&gt;±&lt;/mo&gt; &lt;mn&gt;2&lt;/mn&gt; &lt;mspace&gt;&lt;/mspace&gt; &lt;mi&gt;s&lt;/mi&gt; &lt;mo&gt;;&lt;/mo&gt; &lt;mspace&gt;&lt;/mspace&gt; &lt;mi&gt;P&lt;/mi&gt; &lt;mo&gt;=&lt;/mo&gt; &lt;mn&gt;.8&lt;/mn&gt;&lt;/mrow&gt; &lt;annotation&gt;$$ 14pm 2;mathrm{s};kern0.5em P=.8 $$&lt;/annotation&gt;&lt;/semantics&gt; &lt;/math&gt; ). A point-biserial correlation between DCEUS MTT and NM drainage time categories was found to be &lt;math&gt; &lt;semantics&gt; &lt;mrow&gt;&lt;msub&gt;&lt;mi&gt;r&lt;/mi&gt; &lt;mi&gt;pb&lt;/mi&gt;&lt;/msub&gt; &lt;mo&gt;=&lt;/mo&gt; &lt;mn&gt;0.8&lt;/mn&gt;&lt;/mrow&gt; &lt;annotation&gt;$$ {r}_{pb}=0.8 $$&lt;/annotation&gt;&lt;/semantics&gt; &lt;/math&gt; ( &lt;math&gt; &lt;semantics&gt;&lt;mrow&gt;&lt;mi&gt;P&lt;/mi&gt; &lt;mo&gt;&lt;&lt;/mo&gt; &lt;mn&gt;.0001&lt;/mn&gt;&lt;/mrow&gt; &lt;annotation&gt;$$ P&lt;.0001 $$&lt;/annotation&gt;&lt;/semantics&gt; &lt;/math&gt; ). Similar patterns were observed for TTP and FWHM, however, they were not statistically significant. The results showed potential of DCEUS MTT in categorizing kidneys into delayed and normal, according to their NM drainage time (ROC AUC = 0.97, 95% CI = [0.9, 1.0])","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Proof of Concept: Super-Resolution Ultrasound and Viscoelastic Imaging of Hepatic Microcirculation for Early Detection and Staging of Liver Fibrosis in a Murine Model.","authors":"Rui Zhang, Jieqiong Wang, Tingting Liu, Yan Wang, Shuai Yang, Fei Yan, Li Xue","doi":"10.1002/jum.16703","DOIUrl":"https://doi.org/10.1002/jum.16703","url":null,"abstract":"<p><strong>Objectives: </strong>Super-resolution ultrasound microvascular imaging (SRUS) has emerged as a noninvasive technology capable of visualizing the microvasculature with exceptional spatial resolution, surpassing the acoustic diffraction limit. This study aims to assess the potential of SRUS in staging liver fibrosis by evaluating its diagnostic performance against ultrasound viscosity imaging.</p><p><strong>Methods: </strong>Liver fibrosis was induced by carbon tetrachloride (CCl₄) in 30 mice. The mice were evenly distributed across five stages (6 mice per stage), categorized from F0 (no fibrosis) to F4 (cirrhosis) based on the extent of collagen deposition. SRUS microvascular imaging and ultrasound viscosity imaging were compared for their efficacy in detecting liver fibrosis stages. Immunohistochemistry and histopathological analyses were conducted to correlate vessel density and collagen deposition.</p><p><strong>Results: </strong>SRUS effectively detected microvascular changes across all fibrosis stages. Significant vessel diameter enlargement was observed at early stages (F1), with further increases in advanced stages (F3-F4). Vessel density significantly decreased in later stages, indicating compromised angiogenesis. Ultrasound viscosity imaging showed marked viscoelastic reductions in fibrosis but lacked sensitivity in early-stage detection. SRUS parameters exhibited strong correlations with histological findings, underscoring their potential diagnostic value. Receiver operating characteristic (ROC) curve analysis further demonstrated the superior sensitivity of SRUS (89.59% [95% confidence interval (CI): 84.87-92.96%]), particularly in distinguishing early-stage fibrosis (F0-F1) from advanced stages (F2-F4) (area under the curve [AUC] = 0.9610, 95% CI: 0.9449-0.9771; P < .001).</p><p><strong>Conclusions: </strong>SRUS microvascular imaging is a promising adjunct to traditional elastography, offering enhanced sensitivity for early-stage liver fibrosis detection. It provides critical insights into microcirculatory dysfunction, complementing stiffness measurements and aiding in accurate diagnosis.</p>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to \"Machine Learning Model for Predicting Axillary Lymph Node Metastasis in Clinically Node Positive Breast Cancer Based on Peritumoral Ultrasound Radiomics and SHAP Feature Analysis\".","authors":"","doi":"10.1002/jum.16692","DOIUrl":"https://doi.org/10.1002/jum.16692","url":null,"abstract":"","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143788092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Fetal Posterior Fossa Anomalies at 11-13⁺⁶ Gestational Weeks in the Midsagittal Cranial Plane by Three-Dimensional Multiplanar Sonography: A Prospective Study.","authors":"Feng-Qin Liu, Ze-Xuan Yang, Lin-Hua Yang, Ji-Mei Xi, Lin Chen, Liu-Ying Zhou, De-Xin Chen","doi":"10.1002/jum.16691","DOIUrl":"https://doi.org/10.1002/jum.16691","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to describe the sonographic appearance of posterior fossa anomalies in fetuses at 11-13⁺⁶ weeks' gestation.</p><p><strong>Methods: </strong>This prospective study included 60 healthy fetuses and 15 fetuses with an abnormal posterior brain at 11-13⁺⁶ weeks' gestation. All three-dimensional images were processed using multiplanar image correlation to view the posterior fontanelle in the midsagittal views. The final diagnosis of all fetuses was confirmed using second-trimester ultrasonography, fetal magnetic resonance imaging, and/or genetic testing.</p><p><strong>Results: </strong>The brainstem morphology, fourth ventricle, choroid plexus of the fourth ventricle, vermis, and physiologic Blake pouch were clearly visualized at 11-13⁺⁶ weeks' gestation through the posterior fontanelle from the midsagittal view. Among the 15 fetuses analyzed, two had abnormal brainstem morphology, which was subsequently diagnosed as Walker-Warburg syndrome. The remaining 13 fetuses were diagnosed with posterior fossa cystic malformations (Dandy-Walker malformation, 2 fetuses; Blake's pouch cyst, 2 fetuses; Noonan syndrome, 1 fetus; trisomy 21, 2 fetuses; trisomy 18, 1 fetus; and transient dilatation of the fourth ventricle, 5 fetuses). The extended anterior membranous area and dysplastic vermis were strong markers of Dandy-Walker malformation. In fetuses with Blake pouch cysts, the vermis was visible, with the choroid plexus of the fourth ventricle located backward.</p><p><strong>Conclusions: </strong>Sonography enables clear visualization of morphological changes in posterior fossa anomalies at 11-13⁺⁶ gestational weeks. An extended anterior membranous area, dysplastic vermis, and abnormal brainstem morphology are direct signs of early recognition of severe posterior fossa anomalies.</p>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143788085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"International Multicentric Study on Ultrasound Characteristics, Layer Location, and Corporal Distribution of Granulomas After Cosmetic Fillers Injections.","authors":"Ximena Wortsman, Yessenia Valderrama, Gabriela Ortiz-Orellana, Claudia Gonzalez, Francisco de Cabo, Stella Desyatnikova, Fernanda Aquino Cavallieri, Patricia Barrera, Rosa Sigrist","doi":"10.1002/jum.16700","DOIUrl":"https://doi.org/10.1002/jum.16700","url":null,"abstract":"<p><strong>Objectives: </strong>To provide insight into the characteristics, layer locations, and corporal distribution of the granulomatous reactions to cosmetic fillers.</p><p><strong>Methods: </strong>An international retrospective multicentric study was performed in centers that scan complications of cosmetic fillers. Inclusion criteria were patients with previous injections of known cosmetic fillers confirmed by ultrasound and ultrasonographic features of granulomatous reactions such as hypoechoic nodules, pseudonodules, or hypoechoic tissue surrounding the deposit regions. The ultrasound studies followed the published guidelines for performing dermatologic ultrasound examinations.</p><p><strong>Results: </strong>A total of 240 cases met the criteria. The leading fillers previously injected were 50.4% hyaluronic acid, 18.8% poly-L-lactic acid, 8.3% polymethylmethacrylate, 6.3% calcium hydroxyapatite, and 3.8% silicone oil. The main regions of granulomas were the lower lid, infraorbital, and medial cheek in 41.7%, the perioral region and lips in 19.2%, the lateral jaw and cheek in 14.6%, and the chin, pre-jowl, and medial jaw in 12.5%. The layers involved by the granulomatous reaction were hypodermis in 37.1%, the deep fat pad in 8.9%, the periosteum in 5.8%, the combination of hypodermis, deep fat pad, and muscle in 5.8%, and the combination of hypodermis, fascia, subfascial, deep fat pad, and muscle in 5.4%. The predominant corporal locations were the face, submandibular, and anterior neck, with 95.8% being 87.5% in the face.</p><p><strong>Conclusion: </strong>Ultrasound can provide valuable and detailed anatomical information supporting diagnosis and management as well as valuable insights into the granulomatous reactions to fillers.</p>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143788279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of an Ultrasound-Based Clinical-Radiomic Nomogram for Predicting Histologic Subtypes in Focal Testicular Tumors.","authors":"Tuo Lin, Shunping Chen, Shouliang Miao","doi":"10.1002/jum.16701","DOIUrl":"https://doi.org/10.1002/jum.16701","url":null,"abstract":"<p><strong>Objectives: </strong>Testicular tumors are the most common solid malignancy among males aged 15-35. This study aimed to establish an ultrasound (US) based clinical-radiomic nomogram for the preoperative prediction of testicular tumors histologic subtypes, differentiating testicular germ cell tumors (TGCTs) from testicular non-germ cell tumors (TNGCTs) and then differentiating seminomas (SGCTs) from non-seminomatous tumors (NSGCTs).</p><p><strong>Methods: </strong>This retrospective study included 148 patients with testicular tumors confirmed by pathology, with 120 cases of TGCTs, including 65 SGCTs and 55 NSGCTs. All patients underwent preoperative ultrasound examinations, and data on clinical information, US features, and radiomics features were collected. The Radscore model was constructed after feature selection. Independent risk factors were identified using univariate and multivariate logistic regression analysis. The nomogram model was assessed using the receiver operating characteristic (ROC) curve analysis and decision curve analysis (DCA).</p><p><strong>Results: </strong>The TGCTs radiomics nomogram model achieved AUCs of 0.89 in both the training and validation datasets. The SGCTs radiomics nomogram model achieved AUCs of 0.93 in the training dataset and 0.91 in the validation dataset, surpassing the predictive performance of both Radscore and clinical models. The calibration curves showed that the nomogram estimation was consistent with the actual observations. DCA also verified the clinical value of the combined model.</p><p><strong>Conclusions: </strong>The ultrasound-based clinical-radiomics nomogram has the potential to non-invasively discriminate the histologic subtypes of testicular tumors.</p>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143772580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictive Value of Renal Resistive Index in Occult Hemorrhage in Hemodynamically Stable Polytrauma Patients in Emergency Department.","authors":"Mustafa Arslan, Bedriye Müge Sönmez, Gülşen Akçay","doi":"10.1002/jum.16696","DOIUrl":"https://doi.org/10.1002/jum.16696","url":null,"abstract":"<p><strong>Objectives: </strong>To find out if renal resistive index (RRI) is altered early in the course of posttraumatic hemorrhage and if it may be a surrogate marker of silent hypoperfusion and, in turn, hemorrhagic shock in polytrauma patients presenting to the emergency department (ED).</p><p><strong>Methods: </strong>A prospective single-center cross-sectional study was conducted on 195 patients presenting to the ED with hemodynamically stable polytrauma. The patients were evaluated according to the extended-focused assessments with sonography for trauma (e-FAST) protocol and then underwent RRI measurement using Doppler ultrasonography (US). Measurements were performed by an ED physician with a minimum of 4 years' experience in ED practice and USG examination, plus a certification to perform basic and advanced US training. The primary outcome was the development of hemorrhagic shock according to the American College of Surgeons Advanced Trauma Life Support (ATLS) hemorrhagic shock classification. The secondary outcome was the diagnostic performance of RRI in determining occult hemorrhage.</p><p><strong>Results: </strong>A total of 84 patients (43.1%) developed hemorrhagic shock. There was a significant difference between the RRI levels of the groups with and without hemorrhagic shock (P < .05). While most of the patients with a mean RRI of <0.05 did not develop hemorrhagic shock, to the contrary, patients with a mean RRI of >0.07 mainly developed hemorrhagic shock. When we used the RRI value as a diagnostic test to detect patients who developed hemorrhagic shock, the area under the curve value was 0.832 (P < .001).</p><p><strong>Conclusion: </strong>RRI can be a promising noninvasive, early marker of silent hemorrhage.</p>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143753475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Novel Solid Hydrogel Sleeve Couplant for Ultrasound Imaging.","authors":"Yunlong Bao, Jiabin Zhang, Jinyu Yang, Yu Xia, Dongdong Liang, Yunlong Zhao, Hao Yu, Shuo Huang, Wenyu Guo, Jue Zhang","doi":"10.1002/jum.16690","DOIUrl":"https://doi.org/10.1002/jum.16690","url":null,"abstract":"<p><strong>Objectives: </strong>To address the challenges of ultrasound scanning on curvilinear skin surfaces at joints, this study introduces a novel Shapable and Elastic Couplants sleeve of Hydrogel (SECH) based on a \"Curve-to-Smooth\" strategy. The aim is to improve acoustic wave transmission, enhance image quality, and enable efficient 3D imaging of high-curvature body parts such as the hand, foot, shoulder, and neck.</p><p><strong>Methods: </strong>The SECH was fabricated using acrylamide (AAm) as the primary monomer, N,N-methylenebisacrylamide (MBAA) as the crosslinking agent, ammonium persulfate (APS) as the initiator, and N,N,N',N'-tetramethylethylenediamine (TEMED) as the accelerator. A dual-mold strategy was employed to shape the hydrogel to specific body parts. Mechanical characterization was performed using tensile tests and manual stretching/compression cycles. Ultrasound imaging was conducted on a healthy adult male volunteer using the Vevo F2 system with an L38 linear probe transducer. Cyclic scans were performed on the hand, foot, shoulder, and neck, and 3D image reconstruction was achieved using Matlab and ImageJ.</p><p><strong>Results: </strong>The SECH demonstrated effective mechanical properties, balancing softness and hardness to minimize air gaps and ensure stable acoustic wave transmission. Ultrasound imaging with SECH enabled high-quality 3D reconstructions of high-curvature body parts, including the hand, foot, shoulder, and neck. Multi-planar analysis of the images provided detailed diagnostic information for conditions such as hand fractures, Achilles tendon injuries, shoulder dislocations, and carotid artery stenosis.</p><p><strong>Conclusion: </strong>The SECH represents a novel ultrasound scanning strategy that overcomes the limitations of conventional rigid probes on curvilinear surfaces. It facilitates large-area 3D imaging of high-curvature body parts, improving diagnostic accuracy and efficiency in clinical ultrasonography. This customizable hydrogel sleeve has the potential to enable convenient and automated ultrasound scanning for irregular anatomical areas.</p>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143753471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}