Journal of Ultrasound in Medicine最新文献

{"title":"Median Nerve and Carpal Tunnel Variations: Clinical Relevance and Imaging Considerations.","authors":"Enes Gurun, Mesut Ozturk, Atiye Cenay Karabork Kilic, Ahmet Emin Okutan","doi":"10.1002/jum.16766","DOIUrl":"https://doi.org/10.1002/jum.16766","url":null,"abstract":"","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144560488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multi-Institutional Survey of 4-Year Ultrasound Quality Control Findings.","authors":"Zaiyang Long, Megan Russ, Sandra Larson, Mark R Holland, Zheng-Feng Lu, Cameron Kofler, Wei Zhou, Jian-Feng Chen, Zhimin Li, James Zagzebski, Jennifer Stickel, Andreea Dohatcu","doi":"10.1002/jum.16763","DOIUrl":"https://doi.org/10.1002/jum.16763","url":null,"abstract":"<p><strong>Objectives: </strong>Periodic quality control (QC) testing of ultrasound (US) imaging systems is essential to ensure and maintain image quality and safety. The study aims to analyze QC findings from medical physics annual surveys of modern clinical US systems in a multi-institutional survey.</p><p><strong>Methods: </strong>QC results from annual surveys between 2018 and 2021 were retrospectively collected from 12 medical physicists from 11 institutions or consulting companies (hereafter referred to as sites). QC tests were classified as scanner- and transducer-related tests, where scanner-related tests also included evaluation of diagnostic workstation display monitors and routine QC programs if applicable. Test methodology and pass/fail criteria were established by each site. QC findings were defined as results requiring follow-up action by service engineers, vendors, or other personnel. The percentage of annual findings was calculated for each site and averaged across the years of data contributed. Furthermore, findings across all sites were aggregated for an overall analysis.</p><p><strong>Results: </strong>QC data from a total of 1069 scanner tests and 4542 transducer tests were collected. The average annual percentage of scanner-related findings varied from 0 to 40.8% among all sites (first quartile 8.7%, median 18.2%, and third quartile 34.1%), while that of transducer-related findings ranged between 0.5% and 19.9% (first quartile 3.9%, median 7.2%, and third quartile 14.5%). For scanner-related tests, the top 3 categories of findings were associated with physical and mechanical integrity (171 findings, 74.7%), quantitative testing of the scanner display monitor (40 findings, 17.5%), and scanner port creating artifacts (10 findings, 4.4%). The top 3 findings for transducers related to uniformity and artifact (227 findings, 79.9%), physical and mechanical integrity (44 findings, 15.5%), and sensitivity in fundamental mode (9 findings, 3.2%).</p><p><strong>Conclusions: </strong>Medical physics annual surveys revealed considerable actionable findings of modern US systems, which inform the status of current US QC practices in the United States and may guide future standardization and recommendation of QC tests.</p>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144553812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Influence of Probe Pressure on Appendix Visualization in Pediatric Sonography: A Pilot Study.","authors":"Rayan A Ahyad","doi":"10.1002/jum.16757","DOIUrl":"https://doi.org/10.1002/jum.16757","url":null,"abstract":"<p><strong>Objectives: </strong>To investigate the influence of ultrasound probe pressure on the visualization of the appendix sonographically.</p><p><strong>Methods: </strong>Pediatric outpatients undergoing routine renal ultrasound (US) were approached for additional images using a standardized imaging protocol. The movement of the normal appendix (base and distal parts) was documented while applying probe pressure. The minimum pressure required for appendix identification and the maximum pressure required to elicit movement out of the field-of-view were recorded using a force sensor. Skin thickness was measured at baseline, at first appendix identification, and at maximal pressure. Appendiceal locations and peri-appendicular findings were also recorded.</p><p><strong>Results: </strong>Forty-six US scans were included in the final analysis. The appendix was identified in all scans. Movement out of the field-of-view was documented in 30 scans, of which 12 showed movement of the entire appendix, 11 of the distal appendix, and seven of the appendicular base only. The mean pressure was lower when the appendix was identified than when its base and distal part moved out of the field-of-view. The mean skin thickness was comparable. Neither pressure nor skin thickness showed a statistically significant correlation with appendix movement out of the field-of-view.</p><p><strong>Conclusions: </strong>Despite no statistically significant correlation between the applied pressure and the appendiceal movement, since all the appendices were identified with less pressure than the pressure needed to displace most of them out of the field-of-view, it is possible that the non-visualization of the appendix is attributed to the displacement of the organ due to excessive sonographic pressure.</p>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144540679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corpus Callosum to Choroid Plexus Distance for the Prenatal Diagnosis of Partial Agenesis or Hypoplasia of the Corpus Callosum: A Multicenter Study.","authors":"Veronica Stanislao, Giuseppe Rizzo, Gianpaolo Grisolia, Ricciarda Raffaelli, Maurizio Arduini, Alessia Pinto, Ilenia Mappa, Marlene Pisello, Chiara Patelli, Benedetto Mazzucca, Barbara Matarrelli, Asma Khalil, Giorgio Pagani, Alessandro Lucidi, Federico Prefumo, Francesco D'Antonio","doi":"10.1002/jum.16760","DOIUrl":"https://doi.org/10.1002/jum.16760","url":null,"abstract":"<p><strong>Objectives: </strong>Prenatal diagnosis of partial agenesis (pACC) or hypoplasia of the corpus callosum (CC) is hindered by the lack of objective and reproducible ultrasound signs. The aim of this study was to report the role of a new ultrasound sign, the distance between the choroid plexus (CP) of the third ventricle and the distal part of the CC, in identifying fetuses with partial agenesis (pACC) or hypoplasia of CC.</p><p><strong>Methods: </strong>Retrospective multicenter case-control study including fetuses with pACC or hypoplasia of the CC confirmed at post-natal imaging or autopsy. The distance between the CP of the third ventricle and its ratio with the length of the CC were compared with unaffected cases on stored images assessed by 2 different examiners. Intraclass correlation, Bland-Altman, univariate, and multivariate logistic regression analyses were used to analyze the data.</p><p><strong>Results: </strong>One hundred and four (29 with pACC or hypoplasia of the CC and 75 controls) were included in the analysis. At univariate analysis, fetuses with pACC or hypoplasia had a larger transverse diameter (3.9 ± 0.7 versus 5.3 ± 1.6 mm; P < .001) and an increased area (31.6 ± 8.8 versus 41.6 ± 15.6 mm²; P < .001) of the CSP compared to unaffected cases. Fetuses with pACC or hypoplasia of the CC had a shorter distance between the CP of the third ventricle and the distal part of the CC (1.6 ± 0.9 versus 8.4 ± 1.8; P < .001) and a higher ratio between the length of the CC and the distance between the CP of the third ventricle and the CC (13.5 ± 9.3 versus 2.6 ± 0.5; P < .001) compared to controls. At multivariate logistic regression analysis, the distance between the CP and the CC (OR: 0.67, 95% CI 0.5-0.7, per 1 mm increase; P < .001) and the ratio between the CC length and the distance between the CP and the CC (OR: 1.4, 95% CI 1.0-1.6; per 1 mm increase; P < .001) were independently associated with pACC or hypoplasia of the CC.</p><p><strong>Conclusions: </strong>Fetuses with pACC or hypoplasia of the CC had a shorter distance between the distal part of the CC and the CP of the third ventricle and a higher ratio of this measurement with the length of the CC. Further prospective study aimed at longitudinally evaluate the relationship between the CC and the CP of the third ventricle are needed to confirm these findings and to elucidate whether these measurements can be integrated in the diagnostic algorithm applied to fetuses with suspected pACC or hypoplasia of the CC.</p>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144540678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Ultrasonography Characteristics of Borderline Ovarian Tumor Subtypes.","authors":"Roni Yoeli-Bik, Ernst Lengyel, Ilan E Timor-Tritsch, Katherine Kurnit, Serghei Puiu, Ryan E Longman, Jacques S Abramowicz","doi":"10.1002/jum.16756","DOIUrl":"https://doi.org/10.1002/jum.16756","url":null,"abstract":"","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144528591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound Radio Frequency Time Series for Tissue Typing: Experiments on In-Vivo Breast Samples Using Texture-Optimized Features and Multi-Origin Method of Classification (MOMC).","authors":"Mahsa Arab, Ali Fallah, Saeid Rashidi, Maryam Mehdizadeh Dastjerdi, Nasrin Ahmadinejad","doi":"10.1002/jum.16745","DOIUrl":"https://doi.org/10.1002/jum.16745","url":null,"abstract":"<p><strong>Objectives: </strong>One of the most promising auxiliaries for screening breast cancer (BC) is ultrasound (US) radio-frequency (RF) time series. It has the superiority of not requiring any supplementary equipment over other methods. This article sought to propound a machine learning (ML) method for the automated categorization of breast lesions-categorized as benign, probably benign, suspicious, or malignant-using features extracted from the accumulated US RF time series.</p><p><strong>Methods: </strong>In this research, 220 data points of the categories as mentioned earlier, recorded from 118 patients, were analyzed. The RFTSBU dataset was registered by a SuperSonic Imagine Aixplorer® medical/research system fitted with a linear transducer. The expert radiologist manually selected regions of interest (ROIs) in B-mode images before extracting 283 features from each ROI in the ML approach, utilizing textural features such as Gabor filter (GF), gray-level co-occurrence matrix (GLCM), gray-level run-length matrix (GLRLM), gray-level size zone matrix (GLSZM), and gray-level dependence matrix (GLDM). Subsequently, the particle swarm optimization (PSO) narrowed the features to 131 highly effective ones. Ultimately, the features underwent classification using an innovative multi-origin method classification (MOMC), marking a significant leap in BC diagnosis.</p><p><strong>Results: </strong>Employing 5-fold cross-validation, the study achieved notable accuracy rates of 98.57 ± 1.09%, 91.53 ± 0.89%, and 83.71 ± 1.30% for 2-, 3-, and 4-class classifications, respectively, using MOMC-SVM and MOMC-ensemble classifiers.</p><p><strong>Conclusions: </strong>This research introduces an innovative ML-based approach to differentiate between diverse breast lesion types using in vivo US RF time series data. The findings underscore its efficacy in enhancing classification accuracy, promising significant strides in computer-aided diagnosis (CAD) for BC screening.</p>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144528592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pelvic Adhesion Ultrasound New Scoring System: A Promising Preoperative Assessment Tool for Laparoscopy.","authors":"Qiuling Guo, Yanru Li, Weiru Lin, Caihong Liu, Jincheng Dai, Guorong Lyu, Shanshan Su","doi":"10.1002/jum.16758","DOIUrl":"https://doi.org/10.1002/jum.16758","url":null,"abstract":"<p><strong>Objective: </strong>To develop a new ultrasound-based scoring system for pelvic adhesions and evaluate its predictive performance through intraoperative findings during laparoscopy.</p><p><strong>Methods: </strong>This prospective study was conducted from April 2023 to June 2024, including 152 adult patients undergoing laparoscopic surgery at our hospital. Imaging and clinical data were collected, and preoperative assessment of pelvic adhesions was performed using a novel ultrasound scoring system. Pearson correlation analysis was used to assess its correlation with the revised American Fertility Society (rAFS) score. The predictive performance, accuracy, and clinical utility of the new scoring system were evaluated from multiple perspectives using receiver operating characteristic (ROC) curves, calibration curves, decision curve analysis (DCA), and clinical impact curves.</p><p><strong>Results: </strong>Pearson correlation analysis showed a strong correlation (correlation coefficient = 0.88, P < .001) between the new ultrasound scoring system and rAFS. The area under the ROC curve (AUC) for predicting mild, moderate, and severe pelvic adhesions using the new scoring system were 0.927, 0.952, and 0.937, indicating good predictive performance. Calibration curve analysis demonstrated high predictive accuracy for pelvic adhesions. DCA indicated strong clinical utility of the new scoring system, and the clinical impact curve showed its ability to accurately identify high-risk pelvic adhesion patients during laparoscopic surgery.</p><p><strong>Conclusions: </strong>The newly established scoring system demonstrated good predictive performance, discrimination, and clinical utility, providing a valuable guiding tool for the prediction of the presence or absence of adhesions.</p>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144528590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations Between Fetal Genetic Abnormalities, Lesion Size, and Postnatal Outcomes Among Pregnancies Complicated by Fetal Omphalocele.","authors":"Helen B Gomez Slagle, Russell S Miller, Vincent P Duron, Ronald J Wapner, Lynn L Simpson, Noelle Breslin","doi":"10.1002/jum.16764","DOIUrl":"https://doi.org/10.1002/jum.16764","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to determine if omphalocele ratios can function as predictors of genetic abnormalities and to assess whether genetic anomalies influence postnatal surgical closure in pregnancies complicated by fetal omphalocele.</p><p><strong>Methods: </strong>This was a retrospective study of pregnancies complicated by fetal omphalocele. Omphalocele size, ratios, and presence of extracorporeal liver were evaluated as predictors of abnormal genetic testing results. Surgical outcomes of subjects with identified genetic abnormalities were compared to those without genetic anomalies. Receiver operating curve analyses were performed to predict abnormal genetic testing.</p><p><strong>Results: </strong>Hundred and thirty-nine fetal omphalocele cases were identified during the study period, with 56 cases included in this analysis. Abnormal genetic results were detected in 9 cases (16.1%). Omphalocele size cut-offs and ratios were poor predictors of genetic abnormality. Patients with genetic findings were more likely to present with smaller omphaloceles. Primary closure occurred in 89% of neonates with a genetic abnormality versus 42.5% of neonates without a genetic anomaly (P = .02).</p><p><strong>Conclusion: </strong>While pregnancies with genetic abnormalities were associated with smaller lesions and higher rates of primary surgical closure, no lesion measurement performed well as a predictor of genetic abnormality. Our findings support offering genetic testing in all cases of fetal omphalocele, regardless of size.</p>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144528588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of 2-Dimensional Speckle Tracking Technology for Trastuzumab-Induced Cardiotoxicity in a New Mouse Model.","authors":"Yingxuan Tu, Huaxing Zhang, Ruoling Han","doi":"10.1002/jum.16755","DOIUrl":"https://doi.org/10.1002/jum.16755","url":null,"abstract":"<p><strong>Objectives: </strong>To establish a mouse model of trastuzumab-induced cardiotoxicity that aligns with clinical standard treatment protocols, assess the extent of histological damage across various chambers of the mouse heart, and investigate whether 2-dimensional speckle tracking echocardiography (2D-STE) can detect early cardiac dysfunction, while comparing the diagnostic effectiveness of various parameters in cardiotoxicity.</p><p><strong>Methods: </strong>Mice were randomly assigned to a trastuzumab group (Trz), a doxorubicin-sequential-trastuzumab group (Dox-Trz), and a control group (Con). A mouse model of cardiotoxicity was developed according to clinical standard treatment protocols. Echocardiographic assessments were conducted prior to the experiment, at the end of the first, third, and fourth weeks, and at the conclusion of the experiment to measure and document cardiac function in the mice. Following this, the hearts of the mice were collected for histological analysis, including histopathological evaluation using H&E staining, quantitative assessment of myocardial fibrosis using Masson staining, and evaluation of myocardial cell apoptosis using a TUNEL kit.</p><p><strong>Results: </strong>H&E staining revealed myocardial cell pathology in the hearts of mice in both the Trz and Dox-Trz groups, whereas no abnormalities were observed in the Con group. Masson staining demonstrated a significant increase in interstitial fibrosis in the hearts of mice in the Trz and Dox-Trz groups, with a higher proportion of collagen fibers in the atria compared to the ventricles, and a higher proportion in the right ventricle compared to the left ventricle, with statistical significance. TUNEL staining results indicated a statistically significant increase in myocardial cell apoptosis in the Trz and Dox-Trz groups compared to the Con group. 2D-STE showed significantly reduced left ventricular global longitudinal strain (GLS) and global radial strain (GRS) from baseline in both Trz and Dox-Trz groups at T2. At T3, GLS and GRS were significantly lower in these groups compared to the Con group. Both groups also exhibited significantly reduced global circumferential strain (GCS) from baseline at T3, with the Dox-Trz group showing significantly lower GCS than the Con group. All differences were statistically significant. However, left ventricular ejection fraction (LVEF), left ventricular fractional shortening (LVFS) parameter only exhibited intergroup differences at T4. Notably, GLS demonstrated the highest diagnostic efficacy for trastuzumab-induced cardiotoxicity.</p><p><strong>Conclusions: </strong>This study confirms that GLS, GRS, and GCS can predict early cardiac dysfunction in a mouse model using 2D-STE. Additionally, histological analysis further validated the overall nature of cardiac damage.</p>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144528587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation Between Ultra-High Frequency Ultrasound (UHFUS) and Histological Features of Typical Lesions in Hidradenitis Suppurativa.","authors":"Alessandra Michelucci, Giammarco Granieri, Cristian Scatena, Bianca Cei, Flavia Manzo Margiotta, Teresa Oranges, Marco Romanelli, Valentina Dini","doi":"10.1002/jum.16759","DOIUrl":"https://doi.org/10.1002/jum.16759","url":null,"abstract":"<p><strong>Objectives: </strong>Hidradenitis suppurativa (HS) is a chronic inflammatory disease affecting hair follicles, significantly impacting patients' quality of life. While clinical assessment remains the cornerstone of diagnosis and staging, ultrasound (US) has emerged as a valuable tool for disease evaluation, treatment guidance, and monitoring. The introduction of ultra-high frequency ultrasound (UHFUS) allowed for near in vivo histopathological examination of HS lesions. This study aimed to correlate UHFUS features with histopathological findings in HS lesions.</p><p><strong>Methods: </strong>Three patients at different disease stages underwent pre-surgical UHFUS mapping using a 70 MHz linear probe. Regions of interest (ROIs) were identified and marked preoperatively. Patient 1 had an abscess and perilesional skin, Patient 2 had a draining abscess, and Patient 3 had a clinically evident tunnel. Local excision was performed for Patient 1, while wide excision was conducted for Patients 2 and 3. Tissue samples underwent histological examination, and UHFUS findings were analyzed by three independent observers in consultation with a pathology expert.</p><p><strong>Results: </strong>UHFUS demonstrated the ability to delineate fluid collections, tunnels, and subclinical lesions with high precision. Case 1 revealed a fluid collection with an intra-lesional drop-shaped inclusion, corresponding histologically to a neutrophilic abscess with keratin-filled cysts. Case 2 showed an elongated inclusion within a fluid collection, which histology confirmed as a keratin cyst linked to a tunnel. Case 3 exhibited a tunnel structure characterized by hyperechoic bands on UHFUS, correlating histologically with a keratinized epithelial-lined tunnel.</p><p><strong>Conclusions: </strong>These findings highlight UHFUS as a non-invasive tool enhancing HS assessment, bridging clinical and histopathological evaluation. Further research is needed to standardize parameters and optimize its clinical utility.</p>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144528589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}