Journal of Ultrasound in Medicine最新文献

{"title":"Doppler High-Frequency Ultrasound in Vascular Complications","authors":"Luciana Carmen Zattar,&nbsp;Luca Campassi Bonini,&nbsp;Gabrielle Aline Zattar,&nbsp;Gladstone Eustáquio de Lima Faria,&nbsp;Ricardo Frota Boggio,&nbsp;Giovanni Guido Cerri,&nbsp;Natally Horvat","doi":"10.1002/jum.70396","DOIUrl":"10.1002/jum.70396","url":null,"abstract":"<p>The increase in the number of injectable filler procedures has led to a rise in associated complications, with vascular compromise being the most feared. As a result, blood flow can be interrupted, leading to ischemia, necrosis or ulcerations, pulmonary embolism, blindness, and cerebral vascular injuries. In this context, Doppler high-frequency ultrasound (DHFUS) is a radiological tool that can be used to avoid, to diagnose, and to treat vascular complications. This study aims to review facial vessels anatomy and major variations, describe the examination technique, probe positions and teach how to recognize vascular occlusions, in order to avoid negative outcomes.</p>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":"45 11","pages":"2571-2588"},"PeriodicalIF":2.1,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148794915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound-Guided Radiofrequency Ablation of Benign Thyroid Nodules: 2-Year Follow-Up Results From a Single Center","authors":"Jimei Sun MM,&nbsp;Xiaowen Huang MM,&nbsp;Lusheng Zhang MB,&nbsp;Yongping Lin MB,&nbsp;Wenjuan Chen MB,&nbsp;Bin Zou MB,&nbsp;Huabin Chen MM,&nbsp;Weiquan luo MB,&nbsp;Fuqiang Zeng MM","doi":"10.1002/jum.70346","DOIUrl":"10.1002/jum.70346","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Ultrasound-guided radiofrequency ablation (RFA) is an effective alternative to surgery for benign thyroid nodules (BTNs). This study aimed to evaluate the 2-year clinical outcomes of RFA, focusing on volume reduction rate across different baseline volume strata.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This single-center prospective study included 200 patients with 213 BTNs treated with RFA. Nodules were stratified into 3 groups based on baseline volume: Group A (&lt;5 mL, <i>n</i> = 91), Group B (5–15 mL, <i>n</i> = 95), and Group C (&gt;15 mL, <i>n</i> = 27). Clinical outcomes were assessed at 6, 12, 18, and 24 months. The primary metrics were the volume reduction rate (VRR), therapeutic success (VRR &gt;50%), and complication rates.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>RFA resulted in continuous and significant volume reduction. Median VRR increased from 66.06% at 6 months to 97.08% at 24 months. Distinct reduction patterns were observed: at 6 months, larger nodules (Group C) exhibited a higher VRR (85.40%) than Group A (59.51%) and Group B (64.33%) (<i>p</i> = .001). However, disparities narrowed over time. By 24 months, all groups achieved comparable outcomes (VRR: 97.67, 95.22, and 98.53%, respectively). Therapeutic success ranged from 92.3 to 100%. Regrowth occurred in 2.8% of cases. The complication rate was 2.5% with no major events.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>RFA demonstrates favorable long-term efficacy. Larger nodules shrink faster initially, while smaller nodules reduce gradually but eventually achieve comparable success. Patients with smaller nodules should be counseled to expect a more gradual volume reduction process.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":"45 11","pages":"2521-2530"},"PeriodicalIF":2.1,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148295263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Residual Myometrial Thickness and Scar Elastography After Single- Versus Double-Layer Uterine Closure Following Primary Cesarean Delivery","authors":"Gökçe Ünal MD,&nbsp;Yaşam Kemal Akpak MD,&nbsp;Eda Güner Özen MD,&nbsp;Kübra Adsaz Parlar MD,&nbsp;Sezin Çömez MD,&nbsp;Ahkam Göksel Kanmaz MD","doi":"10.1002/jum.70433","DOIUrl":"10.1002/jum.70433","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To compare residual myometrial thickness and cesarean scar elastography findings following single- versus double-layer uterine closure in women undergoing primary cesarean delivery.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>In this prospective comparative cohort study, 100 women undergoing primary cesarean delivery at Izmir City Hospital between November 2024 and February 2025 were included. Participants were allocated according to the operating surgeon's routine uterine closure technique into single-layer (<i>n</i> = 50) and double-layer (<i>n</i> = 50) groups. Maternal characteristics, perioperative outcomes, hemoglobin changes, postoperative pain scores, and the requirement for additional hemostatic sutures were recorded. At 6 weeks postpartum, residual myometrial thickness, endometrial thickness, and cesarean scar elastography were assessed by ultrasonography. Exploratory receiver operating characteristic (ROC) analysis was performed to evaluate the discriminatory performance of the imaging parameters.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Baseline demographic and perioperative characteristics were comparable between groups. The single-layer group required more additional intraoperative hemostatic sutures than the double-layer group (<i>p</i> = .002). Perioperative hemoglobin decline, postoperative pain scores, operative duration, and hospital stay did not differ significantly (all <i>p</i> &gt; .05). Residual myometrial thickness (5.7 versus 4.9 mm, <i>p</i> = .001), endometrial thickness (7.9 versus 6.4 mm, <i>p</i> = .042), and elastography scores (11.1 versus 8.2, <i>p</i> &lt; .001) were significantly greater following double-layer closure. Elastography demonstrated the highest discriminatory performance in the exploratory ROC analysis (AUC = 0.827).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Double-layer uterine closure was associated with greater residual myometrial thickness, higher cesarean scar elastography scores, and a reduced need for additional hemostatic sutures than single-layer closure. These findings indicate more favorable early postoperative scar characteristics; however, their clinical significance and implications for long-term reproductive and obstetric outcomes remain uncertain.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":"45 11","pages":"2559-2567"},"PeriodicalIF":2.1,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148897381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Low Intensity Pulsed Ultrasound Alleviates the Pain of Monosodium Iodoacetate-Induced Osteoarthritis in Rats","authors":"Zhihua Liu MM,&nbsp;Yang Dong MM,&nbsp;Peng Xu MM,&nbsp;Xia Chen MM","doi":"10.1002/jum.70339","DOIUrl":"10.1002/jum.70339","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Osteoarthritis pain is a common chronic pain. Low intensity pulsed ultrasound (LIPUS) is a non-invasive treatment commonly used for musculoskeletal system diseases, but it is unclear whether it can alleviate osteoarthritis (OA) pain. The aim of this study is to investigate the therapeutic effects of LIPUS on pain relief and joint repair in OA rat models, and to explore its potential mechanisms.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Twenty-four Sprague–Dawley rats were divided into Sham, monosodium iodoacetate (MIA), MIA + LIPUS, and MIA + Sham LIPUS groups. OA was induced via intra-articular MIA injection. LIPUS was administered for 20 minutes/14 days. Behavioral tests, quantitative real-time reverse transcription polymerase chain reaction (qRT-PCR), histopathological, and immunohistochemical assessments were conducted.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>LIPUS significantly increased paw withdrawal thresholds (PWT) and thermal withdrawal latencies (PWL), improved gait symmetry, and enhanced total walking distance. <i>Piezo1</i>, <i>Piezo2</i>, <i>Trpv1</i>, and <i>Calca</i> (encoding CGRP) mRNA levels in dorsal root ganglia were downregulated. Histopathological and immunohistochemical analysis revealed that LIPUS treatment preserved cartilage matrix integrity, reduced cartilage surface erosion, decreased Mankin scores, and promoted cartilage regeneration.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>LIPUS significantly alleviated OA-induced pain and joint damage in rats by downregulating mRNA expression of pain-related molecules and promoting cartilage preservation. These findings suggested that LIPUS has the potential to be a non-invasive, non-pharmacological therapy for OA, offering a promising alternative to conventional treatments.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":"45 11","pages":"2475-2486"},"PeriodicalIF":2.1,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148272192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accuracy of Key Sonographic Markers for Juxta-Articular Fractures","authors":"Xiaofang Fu MM,&nbsp;Lirong Liu PhD,&nbsp;Hao Sun MM,&nbsp;Changqin Sun MM,&nbsp;Qinhan Yang ME,&nbsp;Mengjie Dou MM,&nbsp;Duo Shi MM,&nbsp;Junpu Hu MM,&nbsp;Zhiming He BM,&nbsp;Guangquan Zhou PhD,&nbsp;Shiyu Jin MM,&nbsp;Faqin Lv MD","doi":"10.1002/jum.70342","DOIUrl":"10.1002/jum.70342","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Objectives&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;To systematically evaluate sonographic features of long bone juxta-articular fractures and identify key diagnostic predictors using machine learning-based feature selection.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Methods&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;This prospective single-center diagnostic accuracy study enrolled 121 patients with clinically suspected juxta-articular fractures. Ten predefined sonographic features were assessed, with computed tomography (CT) serving as the reference standard. Key features were identified using shapley additive explanations (SHAP), and the 3 top-ranked features were used to construct a decision tree–based sonographic triad model, hereafter referred to as the sonographic triad model. This model generated a final binary ultrasound diagnosis for each suspected fracture site. Agreement between the final binary ultrasound diagnosis and CT was quantified using Cohen's κ with 95% confidence intervals (CIs). Inter-observer and intra-observer agreement was evaluated using blinded dual-reader review across the cohort. Diagnostic performance was quantified by sensitivity, specificity, predictive values, and the area under the receiver operating characteristic curve (AUC).&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Results&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Analysis of 209 suspected juxta-articular fracture sites revealed that subcutaneous soft-tissue edema (88.5%), cortical separation (50.7%), and heterogeneous intra-articular effusion (56.9%) were the most prevalent findings. The SHAP analysis identified a specific predictive triad. The 3 primary predictors were subperiosteal hematoma (43.8% contribution), arc-shaped fracture end (28.3%), and heterogeneous intra-articular effusion (26.6%). These 3 features collectively accounted for 98.7% of the total feature importance and demonstrated high reproducibility, with good inter-observer agreement (κ = 0.833–0.980) and excellent intra-observer agreement (κ = 0.987–1.000). The final binary ultrasound diagnosis generated by the sonographic triad model demonstrated near-perfect agreement with CT at the suspected fracture-site level (κ = 0.904, 95% CI: 0.847–0.962). In addition, the sonographic triad model achieved excellent diagnostic performance, with a sensitivity of 93.0%, specificity of 97.2%, positive predictive value (PPV) of 96.8%, negative predictive value (NPV) of 93.8%, and an AUC of 0.966.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Conclusions&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;The sonographic triad model, based on subperiosteal hematoma, arc-shaped fracture end, and heterogeneous intra-articular effusion, demonstrated high diagnostic accuracy and strong","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":"45 11","pages":"2487-2498"},"PeriodicalIF":2.1,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jum.70342","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148302133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Hybrid CNN-Transformer Model With Crossover Boosted Cheetah Optimization for Prenatal Spina Bifida Identification From Ultrasound Images","authors":"Asha Rajasekaran PhD,&nbsp;S.S. Subashka Ramesh PhD","doi":"10.1002/jum.70347","DOIUrl":"10.1002/jum.70347","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Spina bifida is a birth defect caused by the incomplete closure of the neural tube around the spinal cord. Earlier, various deep learning-based models were developed, but they failed to capture the fine details from the ultrasound images that reduce the detection accuracy. Hence, to overcome these challenges, an automated and trustworthy deep learning framework is significant for accurate identification of spina bifida from second-trimester fetal ultrasound images.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This research proposes a novel hybrid convolutional neural network-transformer model for spina bifida identification, where convolutional neural network integration enables the model to extract local features and transformer encoder integration enables the model to capture global contextual dependencies. Further, spatial feature representation is enhanced by using the multi-resolution convolutional neural network blocks and positional encoding. On the other hand, clinically relevant regions are highlighted through the use of a self-attention mechanism within the proposed model. The hyperparameters of the proposed model are fine-tuned using a crossover boosted cheetah optimization algorithm, which integrates the strengths of the Cheetah optimizer and the Crossover Mechanism. Thereby, optimizing the performance of the proposed model and making the model robust to spina bifida identification.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The proposed model achieves robust diagnostic performance, which attains an accuracy of 99.02%, an F1-score of 98.21%, and a lower inference time of 0.88 second, demonstrating its suitability in real-time prenatal ultrasound screening applications.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The proposed model provides an efficient and clinically viable solution for automated prenatal spina bifida detection.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":"45 11","pages":"2533-2551"},"PeriodicalIF":2.1,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148471490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Single-Operator Stress Ultrasound Evaluation of Ulnohumeral Joint Instability Related to Medial Ulnar Collateral Ligament Injury","authors":"Benjamin F. Kopecky DO, MS,&nbsp;Brennan J. Boettcher DO,&nbsp;Christopher L. Camp MD,&nbsp;Jacob L. Sellon MD","doi":"10.1002/jum.70391","DOIUrl":"10.1002/jum.70391","url":null,"abstract":"<p>This article introduces a novel, single-operator stress ultrasound technique for evaluating medial ulnar collateral ligament (MUCL) integrity by assessing medial ulnohumeral joint (MUHJ) widening under valgus stress. Unlike prior methods requiring dual operators, specialized equipment, or the use of hand/wrist weights, this approach was designed for clinical efficiency, reproducibility, and patient comfort. By positioning the patient comfortably in a side-lying position with the elbow flexed to 50°, MUHJ width is measured at baseline (maximally apposed) and manually stressed positions, in a manner that may reduce muscular compensation, avoid viscoelastic creep, and facilitate consistency. While additional research is needed to evaluate clinical feasibility, assess reliability, and compare our technique with previously published methods of dynamic MUCL assessment, the aim of this manuscript is to describe our technique and provide a rationale for its potential utility in musculoskeletal ultrasound practice and research.</p>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":"45 11","pages":"2599-2604"},"PeriodicalIF":2.1,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jum.70391","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148592415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing Treatment Efficacy in Alopecia Areata: A Combined High-Frequency Ultrasound and Superb Microvascular Imaging Study","authors":"Meng Yang MM,&nbsp;Chen Zhao MD,&nbsp;Jia Chen MD,&nbsp;Xin Ai MM,&nbsp;Shouqiang Li MD,&nbsp;Zhuo Wang MD,&nbsp;Zhinuo Li MM,&nbsp;Zhirou Di MM,&nbsp;Bingxue Bai PhD,&nbsp;Xiaoping Leng PhD","doi":"10.1002/jum.70299","DOIUrl":"10.1002/jum.70299","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>The therapeutic goals for alopecia areata (AA) are to suppress local immune inflammation, restore hair follicle structure, and improve surrounding blood perfusion. However, current efficacy evaluations largely rely on subjective clinical observation and lack objective quantitative methods. High-frequency ultrasound (HFUS) can clearly display the location and morphology of hair follicles. Combined with microvascular assessment techniques, it enables quantitative detection of low-velocity blood flow and related parameters, providing an objective basis for evaluating AA treatment efficacy.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Forty-five patients with AA who received intralesional therapy underwent HFUS (measuring epidermal/dermal thickness and hair follicle length/width) and ultrasound microvascular assessment, including spectral Doppler measurement of peak systolic velocity (PSV), resistance index (RI), and power Doppler measurement of vascular index (VI) before and after treatment. Patients were divided into a responder group (<i>n</i> = 37) and an ineffective group (<i>n</i> = 8) based on the reduction rate of the SALT score. The Mann–Whitney <i>U</i> test and Wilcoxon signed-rank test were used for comparisons between groups and within the responder group (pre-treatment versus post-treatment), respectively.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Baseline characteristics showed no statistically significant differences (all <i>p</i> &gt; .05). Patients in the ineffective group exhibited poorer hair follicle morphology (shorter length, greater width, and lower length-to-width ratio), but higher PSV and VI compared to the responder group (<i>p</i> &lt; .05). In the responder group, treatment significantly improved hair follicle morphology, increased PSV and VI (<i>p</i> &lt; .05), but RI showed no change.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>(1) HFUS technology can observe changes in AA hair follicle structure during the diagnosis and treatment process, evaluating the effectiveness of treatment regimens in improving AA disease progression. (2) SMI combined with Doppler flow parameters can monitor changes in the perifollicular microcirculation in AA, reflecting the improvement of microcirculation during the diagnosis and treatment of AA. (3) The synergistic application of HFUS and SMI technologies can provide an objective imaging basis for the clinical evaluation of AA treatment efficacy, demonstrating promising clinical application prospects.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":"45 11","pages":"2431-2442"},"PeriodicalIF":2.1,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148794883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Point-of-Care Ultrasound M-Mode Analysis Using M.mode.ify","authors":"David Crockett MD,&nbsp;Elijah Wyatt MD,&nbsp;Benjamin C Smith MD,&nbsp;Jamal Jones MD,&nbsp;Jennifer Cotton MD,&nbsp;Christopher Kelly MD","doi":"10.1002/jum.70349","DOIUrl":"10.1002/jum.70349","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>M-mode ultrasound provides high temporal resolution imaging by rendering a single scan line over time, enabling precise measurement of rapidly moving structures. Traditional M-mode is limited to real-time acquisition and cannot be applied retrospectively. <i>M.mode.ify</i> is a novel software tool that generates M-mode-like tracings from video data, enabling post-acquisition analysis. This study evaluates the accuracy of <i>M.mode.ify</i> in measuring E-point septal separation (EPSS), a key echocardiographic parameter.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We retrospectively analyzed 50 cardiac ultrasound studies from our institution's quality assurance database. Inclusion criteria required both a saved M-mode EPSS image and a parasternal long axis (PLAX) video clip. EPSS values from M-mode served as the reference standard. Two blinded reviewers independently measured EPSS using <i>M.mode.ify</i>. Inter-rater reliability and agreement with the standard were assessed using Pearson correlation coefficients. Absolute error was calculated to quantify measurement precision.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Of the 50 analyzed studies, 9 were excluded due to inadequate anatomical visualization. Among the 41 included studies, inter-rater correlation was strong (<i>r</i> = 0.90), and agreement between <i>M.mode.ify</i> and standard M-mode measurements was excellent (r = 0.92). The mean absolute error was 2.38 mm (SD 1.71 mm).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p><i>M.mode.ify</i> demonstrates high accuracy and reliability in measuring EPSS retrospectively. This tool may expand the utility of ultrasound data by enabling post hoc analysis of M-mode parameters.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":"45 11","pages":"2553-2557"},"PeriodicalIF":2.1,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jum.70349","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148308751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on “Fetal Heart Rate at 12 Weeks' Gestation and the Risk of Preterm Birth”","authors":"Varshitha Hantur Dinakar MSc,&nbsp;Neeraj Singh MD,&nbsp;Monika Srivastav PhD","doi":"10.1002/jum.70283","DOIUrl":"10.1002/jum.70283","url":null,"abstract":"","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":"45 11","pages":"2613-2614"},"PeriodicalIF":2.1,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147839500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}