Ultrasound Findings of Bile Duct Involvement in Pediatric Langerhans Cell Histiocytosis.

IF 2.1 4区医学 Q2 ACOUSTICS

Journal of Ultrasound in Medicine Pub Date : 2025-05-23 DOI:10.1002/jum.16723

Jiachao Wang, Xin Wei, Yu Wang, Yanxiu Hu, Xiaoman Wang

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Abstract

Objective: This study aimed to analyze the ultrasound findings of bile duct involvement in pediatric Langerhans cell histiocytosis (LCH).

Methods: We retrospectively analyzed 42 patients diagnosed with pediatric LCH by pathology at our hospital from December 2016 to December 2023. All patients had comprehensive clinical data and ultrasound findings indicating biliary abnormalities. This study analyzed intrahepatic and extrahepatic bile duct dilation, the extent of bile duct wall thickening, and surrounding abnormal echoes.

Results: Among the 42 children, ultrasonography showed intrahepatic and extrahepatic bile duct dilation in 27 cases (64%), bile duct wall thickening in 21 cases (50%), hypoechoic areas along the intrahepatic bile ducts in 16 cases (38%), and thickening of the Glisson's capsule with decreased echogenicity around the bile ducts in 8 cases (19%).

Conclusion: Ultrasonography revealing varying degrees of bile duct dilatation or stenosis, thickened bile duct walls, and abnormal echo patterns along the bile duct in the liver in pediatric patients with cholangitis should raise suspicion for LCH.

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小儿朗格汉斯细胞组织细胞增多症胆管受累的超声表现。

目的：分析小儿朗格汉斯细胞组织细胞增多症（LCH）累及胆管的超声表现。方法：回顾性分析我院2016年12月至2023年12月病理诊断为小儿LCH的42例患者。所有患者均有全面的临床资料和超声结果显示胆道异常。本研究分析肝内、肝外胆管扩张、胆管壁增厚程度及周围异常回声。结果：42例患儿超声示肝内、肝外胆管扩张27例（64%），胆管壁增厚21例（50%），沿肝内胆管低回声区16例（38%），胆管周围Glisson囊增厚8例（19%）。结论：小儿胆管炎超声检查发现胆管不同程度扩张或狭窄，胆管壁增厚，肝内沿胆管回声异常，应引起对LCH的怀疑。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Ultrasound in Medicine 医学-核医学

CiteScore

5.10

自引率

4.30%

发文量

205

审稿时长

1.5 months

期刊介绍： The Journal of Ultrasound in Medicine (JUM) is dedicated to the rapid, accurate publication of original articles dealing with all aspects of medical ultrasound, particularly its direct application to patient care but also relevant basic science, advances in instrumentation, and biological effects. The journal is an official publication of the American Institute of Ultrasound in Medicine and publishes articles in a variety of categories, including Original Research papers, Review Articles, Pictorial Essays, Technical Innovations, Case Series, Letters to the Editor, and more, from an international bevy of countries in a continual effort to showcase and promote advances in the ultrasound community. Represented through these efforts are a wide variety of disciplines of ultrasound, including, but not limited to: -Basic Science- Breast Ultrasound- Contrast-Enhanced Ultrasound- Dermatology- Echocardiography- Elastography- Emergency Medicine- Fetal Echocardiography- Gastrointestinal Ultrasound- General and Abdominal Ultrasound- Genitourinary Ultrasound- Gynecologic Ultrasound- Head and Neck Ultrasound- High Frequency Clinical and Preclinical Imaging- Interventional-Intraoperative Ultrasound- Musculoskeletal Ultrasound- Neurosonology- Obstetric Ultrasound- Ophthalmologic Ultrasound- Pediatric Ultrasound- Point-of-Care Ultrasound- Public Policy- Superficial Structures- Therapeutic Ultrasound- Ultrasound Education- Ultrasound in Global Health- Urologic Ultrasound- Vascular Ultrasound