Journal of Veterinary Science最新文献

{"title":"Effect of Silencing subolesin and enolase impairs gene expression, engorgement and reproduction in <i>Haemaphysalis longicornis</i> (Acari: Ixodidae) ticks.","authors":"Md Samiul Haque, Mohammad Saiful Islam, Myung-Jo You","doi":"10.4142/jvs.24039","DOIUrl":"10.4142/jvs.24039","url":null,"abstract":"<p><strong>Importance: </strong><i>Haemaphysalis longicornis</i> is an obligate blood-sucking ectoparasite that has gained attention due its role of transmitting medically and veterinary significant pathogens and it is the most common tick species in Republic of Korea. The preferred strategy for controlling ticks is a multi-antigenic vaccination. Testing the efficiency of a combination antigen is a promising method for creating a tick vaccine.</p><p><strong>Objective: </strong>The aim of the current research was to analyze the role of subolesin and enolase in feeding and reproduction of <i>H. longicornis</i> by gene silencing.</p><p><strong>Methods: </strong>In this study, we used RNA interference to silence salivary enolase and subolesin in <i>H. longicornis</i>. Unfed female ticks injected with double-stranded RNA targeting subolesin and enolase were attached and fed normally on the rabbit's ear. Real-time polymerase chain reaction was used to confirm the extent of knockdown.</p><p><strong>Results: </strong>Ticks in the subolesin or enolase dsRNA groups showed knockdown rates of 80% and 60% respectively. Ticks in the combination dsRNA (subolesin and enolase) group showed an 80% knockdown. Knockdown of subolesin and enolase resulted in significant depletion in feeding, blood engorgement weight, attachment rate, and egg laying. Silencing of both resulted in a significant (<i>p</i> < 0.05) reduction in tick engorgement, egg laying, egg hatching (15%), and reproduction.</p><p><strong>Conclusions and relevance: </strong>Our results suggest that subolesin and enolase are an exciting target for future tick control strategies.</p>","PeriodicalId":17557,"journal":{"name":"Journal of Veterinary Science","volume":"25 3","pages":"e43"},"PeriodicalIF":1.5,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11156603/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141247801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Histopathological evaluation of the lungs in experimental autoimmune encephalomyelitis.","authors":"Sungmoo Hong, Jeongtae Kim, Kyungsook Jung, Meejung Ahn, Changjong Moon, Yoshihiro Nomura, Hiroshi Matsuda, Akane Tanaka, Hyohoon Jeong, Taekyun Shin","doi":"10.4142/jvs.23302","DOIUrl":"10.4142/jvs.23302","url":null,"abstract":"<p><strong>Importance: </strong>Experimental autoimmune encephalomyelitis (EAE) is an animal model of multiple sclerosis characterized by inflammation within the central nervous system. However, inflammation in non-neuronal tissues, including the lungs, has not been fully evaluated.</p><p><strong>Objective: </strong>This study evaluated the inflammatory response in lungs of EAE mice by immunohistochemistry and histochemistry.</p><p><strong>Methods: </strong>Eight adult C57BL/6 mice were injected with myelin oligodendrocyte glycoprotein_35-55 to induce the EAE. Lungs and spinal cords were sampled from the experimental mice at the time of sacrifice and used for the western blotting, histochemistry, and immunohistochemistry.</p><p><strong>Results: </strong>Histopathological examination revealed inflammatory lesions in the lungs of EAE mice, characterized by infiltration of myeloperoxidase (MPO)- and galectin-3-positive cells, as determined by immunohistochemistry. Increased numbers of collagen fibers in the lungs of EAE mice were confirmed by histopathological analysis. Western blotting revealed significantly elevated level of osteopontin (OPN), cluster of differentiation 44 (CD44), MPO and galectin-3 in the lungs of EAE mice compared with normal controls (<i>p</i> < 0.05). Immunohistochemical analysis revealed both OPN and CD44 in ionized calcium-binding adapter molecule 1-positive macrophages within the lungs of EAE mice.</p><p><strong>Conclusions and relevance: </strong>Taken together, these findings suggest that the increased OPN level in lungs of EAE mice led to inflammation; concurrent increases in proinflammatory factors (OPN and galectin-3) caused pulmonary impairment.</p>","PeriodicalId":17557,"journal":{"name":"Journal of Veterinary Science","volume":"25 3","pages":"e35"},"PeriodicalIF":1.8,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11156594/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141247806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Equine helminths: prevalence and associated risk factors in Gamo Gofa Zone, Ethiopia.","authors":"Yared Abate Getahun, Bekahegn Simeon Tsalke, Abreham Wondimu Buzuneh, Mekoya Mereta Mejo, Wondyfraw Tsegaw Habtewold","doi":"10.4142/jvs.23291","DOIUrl":"10.4142/jvs.23291","url":null,"abstract":"<p><strong>Importance: </strong>Equines are indispensable in reducing the huge burden on children and women and income generation. On the other hand, minimal attention is given to improving their health and welfare.</p><p><strong>Objective: </strong>This study examined the prevalence and associated risk factors of helminth parasites of equine in the Gamo Gofa Zone.</p><p><strong>Methods: </strong>A cross-sectional study was employed from June 2019 to March 2020. The study districts and <i>Kebeles</i> were selected purposively based on agroecology whereas selection of study households and animals were performed based on simple random sampling techniques. Identification of nematode, trematode parasite ova and larvae of <i>D. arnfieldi</i> were done by floatation, sedimentation, and Baermann techniques respectively. Descriptive statistics and logistic regression was applied to estimate the prevalence and association of risk factors with helminth parasites.</p><p><strong>Results: </strong>The overall helminth parasite prevalence in the study area was 90.4%, 425/470 (95% [CI], 87.16-92.9). The prevalence of Strongyle, Fasciola, <i>O. equi</i>, <i>P. equorum</i>, <i>D. arnfieldi</i>, and mixed parasite infections were 65.1%, 21.7%, 17.4%, 34%, 34%, and 58.1%, respectively. Infections from Fasciola species and <i>D. arnfieldi</i> infection were four ([AOR], 4.4; 95% CI, 2-9.4) and two times (AOR, 2; 95% CI, 1.1-3.6) respectively more likely occur in donkeys than in mules. The occurrence of Strongyle species in midland agroecology was two times (AOR, 2.6; 95% CI, 1.4-4.7) more likely than lowland agroecology.</p><p><strong>Conclusions and relevance: </strong>The present study identified diverse species of equine helminth parasites that necessitate urgent disease control and prevention measures.</p>","PeriodicalId":17557,"journal":{"name":"Journal of Veterinary Science","volume":"25 3","pages":"e41"},"PeriodicalIF":1.8,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11156592/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141247846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Symmetric dimethylarginine correlates with the urea, creatinine, potassium, and clinical scores in feline urethral obstructions.","authors":"Jéssica Cavalcante da Nóbrega, Heloíse Rangel Dinallo, Silvano Salgueiro Geraldes, Maria Gabriela Picelli de Azevedo, Reiner Silveira de Moraes, Suellen Rodrigues Maia, Fabiana Ferreira de Souza, Alessandra Melchert, Henry David Mogollón García, Raphael Lúcio Andreatti Filho, Adriano Sakai Okamoto, Priscylla Tatiana Chalfun Guimarães Okamoto","doi":"10.4142/jvs.23268","DOIUrl":"https://doi.org/10.4142/jvs.23268","url":null,"abstract":"<p><strong>Background: </strong>A urethral obstruction (UO) is an emergency commonly observed in male cats, which can result in significant clinical and laboratory alterations, leading to complications and death.</p><p><strong>Objectives: </strong>This study aimed to correlate symmetric dimethylarginine (SDMA) with the urea, creatinine, potassium, and bicarbonate levels in cats with UO. In addition, the correlation between clinical score and time of obstruction was evaluated.</p><p><strong>Methods: </strong>Thirty male cats were selected and allocated into a control group (CG, n = 13) and an obstruction group (OG, n = 17). The laboratory analyses were conducted before treatment (M0) and at different times after treatment (12 h [M12], 24 h [M24], and 48 h [M48]). Correlations were established between SDMA and creatinine, urea, bicarbonate, potassium, time of obstruction, and the clinical score.</p><p><strong>Results: </strong>A strong correlation (r > 0.6) was observed between SDMA and creatinine, urea, and potassium in the OG. Furthermore, there was substantial agreement (kappa value) between SDMA and creatinine at M24. A higher clinical score was associated with a longer time of obstruction. In the OG, at M48, the SDMA and creatinine levels were 50% and 41.2% higher, respectively.</p><p><strong>Conclusions: </strong>A correlation was observed between SDMA and creatinine in obstructed cats, and significant agreement between these values was observed 24 h after the unblocking treatment. A correlation among SDMA, urea, and potassium was observed. Approximately 9% more cats continued to have elevated SDMA levels after 48 h of treatment compared to creatinine. This suggests a slightly lower sensitivity of the latter biomarker but does not exclude the possibility of congruent and normalized values after a longer evaluation period.</p>","PeriodicalId":17557,"journal":{"name":"Journal of Veterinary Science","volume":"25 2","pages":"e27"},"PeriodicalIF":1.8,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10990919/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140867610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isolation and characterization of feline endometrial mesenchymal stem cells.","authors":"Mi-Kyung Park, Kun-Ho Song","doi":"10.4142/jvs.23267","DOIUrl":"https://doi.org/10.4142/jvs.23267","url":null,"abstract":"<p><strong>Background: </strong>Recently, there has been a growing interest in stem cells for human medicine. Limited feline endometrial mesenchymal stem cell (fEM-MSC) research in veterinary medicine necessitates reporting for future feline disease research and therapy.</p><p><strong>Objectives: </strong>This study aimed to isolate fEM-MSCs from feline endometrial tissues and evaluate their morphology, proliferative ability, differentiation ability, and immunophenotype.</p><p><strong>Methods: </strong>Feline endometrial tissues were obtained from the ovariohysterectomies of healthy cats and isolated using an enzymatic method. The morphology and proliferative ability of the isolated cells were assessed using a doubling time (DT) assay from passages 3 to 6 (P3 - P6). We measured pluripotency gene expressions of cells in P2 using quantitative real-time polymerase chain reaction (qRT-PCR). To investigate MSC characteristics, a trilineage differentiation assay was conducted in P4, and cells in P4 were immunophenotyped using flow cytometry.</p><p><strong>Results: </strong>fEM-MSCs showed a typical spindle-shaped morphology under a microscope, and the DT was maintained from P3 to P6. fEM-MSCs could differentiate into adipocytes, osteoblasts, and chondrocytes, and expressed three pluripotency markers (OCT4, SOX2, and NANOG) by qRT-PCR. Immunophenotypic analysis showed that the fEM-MSCs were CD14 ^-, CD34 ^-, CD45 ^-, CD9⁺, and CD44⁺.</p><p><strong>Conclusions: </strong>In this study, the feline endometrium was a novel source of MSCs, and to the best of our knowledge, this is the first report on the isolation method and characteristics of fEM-MSCs.</p>","PeriodicalId":17557,"journal":{"name":"Journal of Veterinary Science","volume":"25 2","pages":"e31"},"PeriodicalIF":1.8,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10990916/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140870643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical evaluation and surgical intervention for diaphragmatic eventration mimicking peritoneopericardial hernia in a cat.","authors":"Min-Jung Ko, Kyoung-Min Song, Hun-Young Yoon","doi":"10.4142/jvs.23277","DOIUrl":"https://doi.org/10.4142/jvs.23277","url":null,"abstract":"<p><p>A 2-year-old spayed female British Shorthair cat presented with an increased frequency and duration of cough since infant period. Based on radiographic, ultrasonographic, and computed tomography findings, peritoneopericardial diaphragmatic hernia was considered so that repair surgery was planned. During celiotomy, lax diaphragm was identified instead of defect. Transabdominal diaphragmatic plication was performed to resolve lax diaphragm and to prevent recurrence by overlapping relatively normal part of diaphragm. Diagnosed with diaphragmatic eventration postoperatively, the cat showed improvement in clinical signs and imaging results. Transabdominal diaphragmatic plication is a suitable treatment; the patient maintained normally during a 14-month follow-up period.</p>","PeriodicalId":17557,"journal":{"name":"Journal of Veterinary Science","volume":"25 2","pages":"e19"},"PeriodicalIF":1.8,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10990918/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140850225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Peste des petits ruminants virus infection induces endoplasmic reticulum stress and apoptosis via IRE1-XBP1 and IRE1-JNK signaling pathways.","authors":"Shuyi Yuan, Yanfen Liu, Yun Mu, Yongshen Kuang, Shaohong Chen, Yun-Tao Zhao, You Liu","doi":"10.4142/jvs.23236","DOIUrl":"https://doi.org/10.4142/jvs.23236","url":null,"abstract":"<p><strong>Background: </strong>Peste des petits ruminants (PPR) is a contagious and fatal disease of sheep and goats. PPR virus (PPRV) infection induces endoplasmic reticulum (ER) stress-mediated unfolded protein response (UPR). The activation of UPR signaling pathways and their impact on apoptosis and virus replication remains controversial.</p><p><strong>Objectives: </strong>To investigate the role of PPRV-induced ER stress and the IRE1-XBP1 and IRE1-JNK pathways and their impact on apoptosis and virus replication.</p><p><strong>Methods: </strong>The cell viability and virus replication were assessed by 3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide assay, immunofluorescence assay, and Western blot. The expression of ER stress biomarker GRP78, IRE1, and its downstream molecules, PPRV-N protein, and apoptosis-related proteins was detected by Western blot and quantitative reverse transcription-polymerase chain reaction, respectively. 4-Phenylbutyric acid (4-PBA) and STF-083010 were respectively used to inhibit ER stress and IRE1 signaling pathway.</p><p><strong>Results: </strong>The expression of GRP78, IRE1α, p-IRE1α, XBP1s, JNK, p-JNK, caspase-3, caspase-9, Bax and PPRV-N were significantly up-regulated in PPRV-infected cells, the expression of Bcl-2 was significantly down-regulated. Due to 4-PBA treatment, the expression of GRP78, p-IRE1α, XBP1s, p-JNK, caspase-3, caspase-9, Bax, and PPRV-N were significantly down-regulated, the expression of Bcl-2 was significantly up-regulated. Moreover, in PPRV-infected cells, the expression of p-IRE1α, p-JNK, Bax, and PPRV-N was significantly decreased, and the expression of Bcl-2 was increased in the presence of STF-083010.</p><p><strong>Conclusions: </strong>PPRV infection induces ER stress and IRE1 activation, resulting in apoptosis and enhancement of virus replication through IRE1-XBP1s and IRE1-JNK pathways.</p>","PeriodicalId":17557,"journal":{"name":"Journal of Veterinary Science","volume":"25 2","pages":"e21"},"PeriodicalIF":1.8,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10990917/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140865613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gross, organoleptic and histologic assessment of cadaveric equine heads preserved using chemical methods for veterinary surgical teaching.","authors":"Rodrigo Romero Corrêa, Rubens Peres Mendes, Diego Darley Velasquez Piñeros, Aymara Eduarda De Lima, André Luis do Valle De Zoppa, Luis Cláudio Lopes Correia da Silva, Ricardo de Francisco Strefezzi, Silvio Henrique de Freitas","doi":"10.4142/jvs.23176","DOIUrl":"https://doi.org/10.4142/jvs.23176","url":null,"abstract":"<p><strong>Background: </strong>Preservation of biological tissues has been used since ancient times. Regardless of the method employed, tissue preservation is thought to be a vital step in veterinary surgery teaching and learning.</p><p><strong>Objectives: </strong>This study was designed to determine the usability of chemically preserved cadaveric equine heads for surgical teaching in veterinary medicine.</p><p><strong>Methods: </strong>Six cadaveric equine heads were collected immediately after death or euthanasia and frozen until fixation. Fixation was achieved by using a hypertonic solution consisting of sodium chloride, sodium nitrite and sodium nitrate, and an alcoholic solution containing ethanol and glycerin. Chemically preserved specimens were stored at low temperatures (2°C to 6°C) in a conventional refrigerator. The specimens were submitted to gross and organoleptic assessment right after fixative solution injection (D0) and within 10, 20, and 30 days of fixation (D10, D20, and D30, respectively). Samples of tissue from skin, tongue, oral vestibule, and masseter muscle were collected for histological evaluation at the same time points.</p><p><strong>Results: </strong>Physical and organoleptic assessments revealed excellent specimen quality (mean scores higher than 4 on a 5-point scale) in most cases. In some specimens, lower scores (3) were assigned to the range of mouth opening, particularly on D0 and D10. A reduced the range of mouth opening may be a limiting factor in teaching activities involving structures located in the oral cavity.</p><p><strong>Conclusions: </strong>The excellent physical, histologic, and organoleptic characteristics of the specimens in this sample support their usability in teaching within the time frame considered. Appropriate physical and organoleptic characteristics (color, texture, odor, and flexibility) of the specimens in this study support the use of the method described for preparation of reusable anatomical specimens.</p>","PeriodicalId":17557,"journal":{"name":"Journal of Veterinary Science","volume":"25 2","pages":"e29"},"PeriodicalIF":1.8,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10990915/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140858800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Butyric acid and prospects for creation of new medicines based on its derivatives: a literature review.","authors":"Lyudmila K Gerunova, Taras V Gerunov, Lydia G P'yanova, Alexander V Lavrenov, Anna V Sedanova, Maria S Delyagina, Yuri N Fedorov, Natalia V Kornienko, Yana O Kryuchek, Anna A Tarasenko","doi":"10.4142/jvs.23230","DOIUrl":"https://doi.org/10.4142/jvs.23230","url":null,"abstract":"<p><p>The widespread use of antimicrobials causes antibiotic resistance in bacteria. The use of butyric acid and its derivatives is an alternative tactic. This review summarizes the literature on the role of butyric acid in the body and provides further prospects for the clinical use of its derivatives and delivery methods to the animal body. Thus far, there is evidence confirming the vital role of butyric acid in the body and the effectiveness of its derivatives when used as animal medicines and growth stimulants. Butyric acid salts stimulate immunomodulatory activity by reducing microbial colonization of the intestine and suppressing inflammation. Extraintestinal effects occur against the background of hemoglobinopathy, hypercholesterolemia, insulin resistance, and cerebral ischemia. Butyric acid derivatives inhibit histone deacetylase. Aberrant histone deacetylase activity is associated with the development of certain types of cancer in humans. Feed additives containing butyric acid salts or tributyrin are used widely in animal husbandry. They improve the functional status of the intestine and accelerate animal growth and development. On the other hand, high concentrations of butyric acid stimulate the apoptosis of epithelial cells and disrupt the intestinal barrier function. This review highlights the biological activity and the mechanism of action of butyric acid, its salts, and esters, revealing their role in the treatment of various animal and human diseases. This paper also discussed the possibility of using butyric acid and its derivatives as surface modifiers of enterosorbents to obtain new drugs with bifunctional action.</p>","PeriodicalId":17557,"journal":{"name":"Journal of Veterinary Science","volume":"25 2","pages":"e23"},"PeriodicalIF":1.8,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10990906/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140859199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mitigation of gap formation resulting from saw blade in single-cut osteotomy.","authors":"Mu-Young Kim, Stanley Eunwoo Kim","doi":"10.4142/jvs.23298","DOIUrl":"https://doi.org/10.4142/jvs.23298","url":null,"abstract":"<p><p>Bone loss from the kerf of the sawblade may influence the final outcomes when employing three-dimensional-printed surgical guides. However, no studies have systematically addressed saw blade-induced bone loss. This study aims to quantify bone loss and propose a reduction guide to minimize the fracture gap. The postoperative gap tended to decrease as the amount of gap compensation increased. Osteotomy gaps can be attributed to the thickness of the saw blade, and the proposed methodology addresses this surgical error. Surgeons can proactively plan and design reduction guides with applied compensation using the method described in this study.</p>","PeriodicalId":17557,"journal":{"name":"Journal of Veterinary Science","volume":"25 2","pages":"e26"},"PeriodicalIF":1.8,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10990914/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140857515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}