Journal of Veterinary Science最新文献

Comparison of cytochrome P450 activity and mRNA expression in canine vs. human hepatocytes after acetaminophen, diclofenac, or valproic acid exposure. 对乙酰氨基酚、双氯芬酸或丙戊酸暴露后犬与人肝细胞细胞色素P450活性和mRNA表达的比较

IF 1.5 3区农林科学

Journal of Veterinary Science Pub Date : 2026-03-01 DOI: 10.4142/jvs.25260

Jea Ran Kang, Juyoung Lee, Han Na Suh

{"title":"Comparison of cytochrome P450 activity and mRNA expression in canine vs. human hepatocytes after acetaminophen, diclofenac, or valproic acid exposure.","authors":"Jea Ran Kang, Juyoung Lee, Han Na Suh","doi":"10.4142/jvs.25260","DOIUrl":"10.4142/jvs.25260","url":null,"abstract":"Importance: Although extensive studies have been conducted on cytochrome P450 (CYP) enzymes in rodents and humans, research on canine CYP enzymes is limited. The lack of species-specific metabolic research on dogs presents a major challenge in predicting toxicity and adverse drug reactions.Objective: This study aimed to examine the interspecies differences in CYP enzyme activity and mRNA expression between canine and human hepatocytes following treatment with acetaminophen (AAP), diclofenac (Dic), or valproic acid (VPA).Methods: We determined the 24-h exposure half-maximal inhibitory concentration (IC₅₀) values of AAP, Dic, and VPA in canine and human hepatocytes. Based on these IC₅₀ concentrations, we compared drug-induced alterations in various parameters, including immunocytochemistry, transcriptomic profiles (RNA-seq), and CYP activity, to assess changes at the gene and protein levels.Results: AAP and VPA increased CYP2J2 mRNA expression by 4.7- and 7.76-fold, respectively, whereas Dic increased CYP1A1 mRNA expression by 14.25-fold in canine hepatocytes. AAP, VPA, and Dic decreased CYP26B1 mRNA expression in canine hepatocytes by 0.03-, 0.12-, and 0.17-fold, respectively. Dic and VPA increased CYP1A1 mRNA expression by 5.53- and 6.66-fold, respectively, whereas AAP, VPA, and Dic decreased CYP4F22 mRNA expression by 0.03-, 0.13-, and 0.13-fold, respectively, in human hepatocytes.Conclusions and relevance: The observed differences between species in CYP activity and mRNA levels in response to drug exposure highlight the importance of accurate and precise experimental models for the development of new medications.","PeriodicalId":17557,"journal":{"name":"Journal of Veterinary Science","volume":"27 2","pages":"e19"},"PeriodicalIF":1.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13062425/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147633524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of a novel percutaneous pinning guide for femoral head or neck fracture: an ex vivo study. 评估一种新型经皮股骨头颈骨折钉钉指南：一项离体研究。

IF 1.5 3区农林科学

Journal of Veterinary Science Pub Date : 2026-03-01 DOI: 10.4142/jvs.25317

Jinyeob Baek, Hyeonseo Lim, Yong Yu, Suyoung Heo

{"title":"Evaluation of a novel percutaneous pinning guide for femoral head or neck fracture: an ex vivo study.","authors":"Jinyeob Baek, Hyeonseo Lim, Yong Yu, Suyoung Heo","doi":"10.4142/jvs.25317","DOIUrl":"10.4142/jvs.25317","url":null,"abstract":"Importance: Accurate Kirschner wire placement is essential for safe and effective femoral fracture repair, yet freehand techniques often lead to variability and increased fluoroscopic use.Objective: To evaluate the precision of a three-dimensional (3D)-printed percutaneous pinning guide (PPG) for Kirschner wire placement in the treatment of femoral fractures using canine cadavers.Methods: The PPG was designed using 3D computer-aided design software and fabricated using medical-grade resin. In part 1, Kirschner wires were inserted into the intact femurs. In part 2, simulated femoral neck fractures were created using a 3D-printed osteotomy guide. Three wires were inserted into each femur under fluoroscopic guidance. The number of insertion attempts, fluoroscopic images, procedure times, and ease of use were recorded. Post-procedural computed tomography was used to assess angular deviation from ideal trajectories and pin engagement in the proximal femur.Results: The PPG group required fewer insertion attempts (p < 0.01), fewer fluoroscopic images (p < 0.001), and had higher ease-of-use scores (p < 0.047) than the freehand pinning technique (FHPT) group; angular deviation was significantly smaller in the proximodistal (2.9 ± 6.5° vs. 10.7 ± 5.9°; p = 0.022) and craniocaudal (4.8 ± 3.0° vs. 12.3 ± 8.8°; p < 0.001) directions. In part 2, the PPG group showed lower angular variance and greater proximal pin engagement than the FHPT group (p = 0.011).Conclusions and relevance: The PPG showed better pinning precision and procedural efficiency than the FHPT under intact and simulated fracture conditions. The PPG may enhance safety and consistency in the percutaneous pinning of canine femoral fractures.","PeriodicalId":17557,"journal":{"name":"Journal of Veterinary Science","volume":"27 2","pages":"e23"},"PeriodicalIF":1.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13062430/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147633670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Surveillance of avian influenza viruses in migratory wild birds in South Korea, 2019-2025. 2019-2025年韩国候鸟中禽流感病毒监测

IF 1.5 3区农林科学

Journal of Veterinary Science Pub Date : 2026-03-01 DOI: 10.4142/jvs.25249

Jae Kyung Lee, Min Beom Kim, Seo Hyeon Kim, Song Hwi Jeong, HaanWoo Sung, Hyung-Kwan Jang, Kang-Seuk Choi, Daesung Yoo, Se-Hee An, Gyeong-Beom Heo, Yong-Myung Kang, Youn-Jeong Lee, Kwang-Nyeong Lee, Young Ju Lee

{"title":"Surveillance of avian influenza viruses in migratory wild birds in South Korea, 2019-2025.","authors":"Jae Kyung Lee, Min Beom Kim, Seo Hyeon Kim, Song Hwi Jeong, HaanWoo Sung, Hyung-Kwan Jang, Kang-Seuk Choi, Daesung Yoo, Se-Hee An, Gyeong-Beom Heo, Yong-Myung Kang, Youn-Jeong Lee, Kwang-Nyeong Lee, Young Ju Lee","doi":"10.4142/jvs.25249","DOIUrl":"10.4142/jvs.25249","url":null,"abstract":"Importance: Wild aquatic birds are reservoirs of avian influenza viruses (AIVs). South Korea has conducted national wild-bird surveillance since 2008 to enable early detection of highly pathogenic AIVs (HPAIVs) and rapid response in poultry.Objective: We investigated the distribution of AI viruses in fecal samples from wild bird habitats (and nearby poultry-farm areas) surveyed between September and March from 2019 to 2025 and identified associated epidemiological risk factors.Methods: Samples were screened for influenza A (M, H5, H7) genes using real-time reverse transcription polymerase chain reaction (PCR), subjected to virus isolation in embryonated chicken eggs, and subtyped by PCR and sequencing. Host species were identified through DNA barcoding. Relative risks (RRs) with 95% confidence intervals were estimated for province, month, and waterfowl density.Results: Overall prevalence of HPAI and low pathogenic AI (LPAI) virus was 0.10% and 3.21%, respectively. HPAI virus was continuously isolated since 2020-2021, except 2019-2020, while LPAI prevalence steadily increased (3.01%-4.35%). Twelve hemagglutinin (H1-H12) subtypes were identified in 1,722 isolates, and H3 (16.5%) was the most prevalent, followed by H5 (11.1%) and H7 (5.2%). LPAI H5N3 (55.7%) and H7N7 (75.5%) were the predominant H5 and H7 subtypes, respectively. Detection was higher in western coastal provinces, and higher mallard/spot-billed duck density and sampling in September-December were associated with increased risk.Conclusions and relevance: Continued surveillance of migratory-bird habitats can provide early warning of HPAIV incursions and support targeted biosecurity measures in high-risk regions and seasons.","PeriodicalId":17557,"journal":{"name":"Journal of Veterinary Science","volume":"27 2","pages":"e8"},"PeriodicalIF":1.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13062435/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147633651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Blood urea nitrogen-to-albumin ratio predicts mortality in dogs with pyometra. 血尿素氮与白蛋白比值预测脓脓狗的死亡率。

IF 1.5 3区农林科学

Journal of Veterinary Science Pub Date : 2026-03-01 DOI: 10.4142/jvs.25266

Minsu Baek, Sang-Yun Lee, Young-Bum Son

{"title":"Blood urea nitrogen-to-albumin ratio predicts mortality in dogs with pyometra.","authors":"Minsu Baek, Sang-Yun Lee, Young-Bum Son","doi":"10.4142/jvs.25266","DOIUrl":"10.4142/jvs.25266","url":null,"abstract":"Importance: Pyometra is a common reproductive disorder in intact female dogs and can progress to sepsis and multi-organ dysfunction. Accurate prognostic indicators are needed to guide clinical management. The blood urea nitrogen-to-albumin ratio (BUN/ALB) has been reported as a prognostic marker in human sepsis but has not been evaluated in canine pyometra.Objective: To evaluate the prognostic value of the BUN/ALB in canine pyometra before and after surgery.Methods: In this retrospective study, BUN/ALB was compared among survivors, non-survivors, and healthy dogs. The BUN/ALB was calculated as blood urea nitrogen (mg/dL) ÷ albumin (g/dL). Analyses included one-way analysis of variance with the Holm-Sidak post hoc test, Mann-Whitney tests, Jonckheere-Terpstra trend analysis, and receiver operating characteristic (ROC) curve analysis.Results: Preoperative BUN/ALB was higher in dogs with pyometra than in healthy dogs, with the highest values in non-survivors. ROC analysis showed an area under the curve (AUC) of 0.86 and an optimal cut-off of 8.935 (sensitivity of 73.08%, specificity of 90.91%). Postoperatively, the BUN/ALB remained higher in non-survivors (AUC, 0.81; cut-off, 8.445; sensitivity, 68.28%, specificity, 83.33%).Conclusions and relevance: The BUN/ALB was significantly associated with mortality in dogs with pyometra both pre- and postoperatively. The BUN/ALB may serve as a simple, inexpensive, and readily available prognostic marker to support clinical decision-making in canine pyometra.","PeriodicalId":17557,"journal":{"name":"Journal of Veterinary Science","volume":"27 2","pages":"e20"},"PeriodicalIF":1.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13062434/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147633571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Process of developing basic veterinary clinical performance guidelines based on common clinical manifestations in Korea. 根据韩国常见临床表现制定兽医基本临床表现指南的过程。

IF 1.5 3区农林科学

Journal of Veterinary Science Pub Date : 2026-03-01 DOI: 10.4142/jvs.25088

Kichang Lee, Heungshik S Lee, Yong Jun Kim, Incheol Park, Kangmoon Seo, Seong Mok Jeong, Kyu-Woan Cho, Jin Young Chung, Dongbin Lee, Chun-Sik Bae, Sung-Lim Lee, Ki-Jeong Na, Sooyoung Choi, Inseong Jeong, Pan Dong Ryu, Sang-Soep Nahm

{"title":"Process of developing basic veterinary clinical performance guidelines based on common clinical manifestations in Korea.","authors":"Kichang Lee, Heungshik S Lee, Yong Jun Kim, Incheol Park, Kangmoon Seo, Seong Mok Jeong, Kyu-Woan Cho, Jin Young Chung, Dongbin Lee, Chun-Sik Bae, Sung-Lim Lee, Ki-Jeong Na, Sooyoung Choi, Inseong Jeong, Pan Dong Ryu, Sang-Soep Nahm","doi":"10.4142/jvs.25088","DOIUrl":"10.4142/jvs.25088","url":null,"abstract":"Importance: Standardized clinical education across veterinary schools is essential for the achievement of core graduation competencies. Thus, a structured set of clinical performance tasks, grounded in clinical signs commonly reported by animal owners, can serve as an effective means to standardize and improve clinical education.Objective: To explain process of developing basic veterinary clinical performance guidelines, based on frequently observable clinical manifestations, thereby supporting competency-based veterinary education in Korea.Methods: A structured review of learning outcomes established by Korean Association of Veterinary Medical Colleges (KAVMC) was conducted by a planning committee including veterinary educators, practitioners, and advisory members. Owner-oriented descriptions were used to frame each performance task, and each was mapped to corresponding learning outcomes. These tasks were aligned with learning outcomes recommended by the KAVMC to support the development of communication, clinical reasoning, and performance-related competencies among veterinary students, thereby enhancing day-one clinical readiness.Results: In total, 63 clinical manifestations for a guidebook format that can be used for clinical education were identified and categorized by organ systems that are described in language understandable to animal owners.Conclusions and relevance: The basic veterinary clinical performance guidelines based on common clinical manifestations would serve as a vital component in veterinary education to reinforce core graduation competencies.","PeriodicalId":17557,"journal":{"name":"Journal of Veterinary Science","volume":"27 2","pages":"e24"},"PeriodicalIF":1.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13062428/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147633634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Radiographic femoral measurements for sex and species classification in dogs and cats using machine learning. 利用机器学习对狗和猫进行性别和物种分类的放射测量。

IF 1.5 3区农林科学

Journal of Veterinary Science Pub Date : 2026-03-01 DOI: 10.4142/jvs.25283

Lutfi Takcı, İbrahim Kürtül

{"title":"Radiographic femoral measurements for sex and species classification in dogs and cats using machine learning.","authors":"Lutfi Takcı, İbrahim Kürtül","doi":"10.4142/jvs.25283","DOIUrl":"10.4142/jvs.25283","url":null,"abstract":"Importance: Sex and species estimation from skeletal remains is important in veterinary forensic medicine, comparative anatomy, and zooarchaeology. Radiographic osteometry has been studied in dogs and cats, but machine-learning approaches have not been well evaluated for this purpose.Objective: To assess the performance of machine-learning models and a multilayer perceptron for estimating sex and species from radiographic femoral measurements in dogs and cats.Methods: This retrospective study analyzed pelvic radiographs of 280 animals (140 dogs and 140 cats; 70 males and 70 females of each species) using 9 radiographic measurements. Random forest, decision tree, logistic regression, extra trees, linear discriminant analysis, quadratic discriminant analysis, and a multilayer perceptron were evaluated. Feature importance was explored with Shapley additive explanations.Results: For sex classification, the extra trees classifier showed the highest accuracy in both dogs (0.79) and cats (0.75). For species classification, logistic regression, quadratic discriminant analysis, and decision tree each achieved an accuracy of 0.89, whereas the multilayer perceptron reached 0.93 after 500 and 1,000 training cycles. The most influential variables were femoral length for sex classification in cats, left intercondylar fossa width for sex classification in dogs, and inter-femoral-head distance for species classification.Conclusions and relevance: Radiographic femoral measurements permit moderate sex classification and high species classification in dogs and cats. These findings support the potential use of machine-learning analysis of femoral radiographs in veterinary forensic medicine and related morphometric fields.","PeriodicalId":17557,"journal":{"name":"Journal of Veterinary Science","volume":"27 2","pages":"e29"},"PeriodicalIF":1.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13062432/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147633613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Paget-like bone remodeling disorder in a red-tailed boa (Boa constrictor constrictor): diagnosis and management. 红尾蟒蛇（蟒蛇）的佩吉特样骨重塑障碍：诊断和治疗。

IF 1.5 3区农林科学

Journal of Veterinary Science Pub Date : 2026-03-01 DOI: 10.4142/jvs.25281

Soong-Hee Youn, Na-Young Lee, Ki-Yong Shin, Hyeon-Joo Shin, Joon-Young Yang, Dae-Yong Kim

{"title":"Paget-like bone remodeling disorder in a red-tailed boa (Boa constrictor constrictor): diagnosis and management.","authors":"Soong-Hee Youn, Na-Young Lee, Ki-Yong Shin, Hyeon-Joo Shin, Joon-Young Yang, Dae-Yong Kim","doi":"10.4142/jvs.25281","DOIUrl":"10.4142/jvs.25281","url":null,"abstract":"Importance: Paget-like bone remodeling disorder is a rare skeletal disease in reptiles, and clinical management strategies are poorly defined. Reporting clinically documented cases may improve recognition and welfare-centered care.Case presentation: A 23-year-old male red-tailed boa (Boa constrictor constrictor) presented with anorexia, dysecdysis and spinal rigidity. Radiography and computed tomography showed diffuse vertebral deformities with irregular bone proliferation, and erosive lesions. Serum alkaline phosphatase activity was markedly increased. Blood cultures yielded Escherichia coli. Treatment with enrofloxacin and dexamethasone was followed by a transient decrease in alkaline phosphatase activity and partial improvement in appetite. Husbandry modifications, including transfer to a larger enclosure, improved mobility and short-term quality of life. The snake later developed recurrent anorexia and dysecdysis and was euthanized for welfare grounds. Necropsy and histopathology revealed extensive vertebral deformities, thickened trabeculae, mosaic lamellar bone and osteoclasts proliferation, consistent with Paget-like bone remodeling disorder.Conclusions and relevance: This case supports the value of imaging, clinicopathologic assessment, and histopathology in diagnosis, and suggests that supportive husbandry modification may provide temporary welfare benefit in affected snakes.","PeriodicalId":17557,"journal":{"name":"Journal of Veterinary Science","volume":"27 2","pages":"e22"},"PeriodicalIF":1.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13062427/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147633665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Behavioral and cardiorespiratory effects of a medetomidine and tramadol combination in horses. 美托咪定和曲马多联合用药对马的行为和心肺的影响。

IF 1.5 3区农林科学

Journal of Veterinary Science Pub Date : 2026-03-01 DOI: 10.4142/jvs.25252

Ahram Kim, Inhyung Lee, Kyuyoung Lee, Eun-Bee Lee, Jong-Pil Seo

{"title":"Behavioral and cardiorespiratory effects of a medetomidine and tramadol combination in horses.","authors":"Ahram Kim, Inhyung Lee, Kyuyoung Lee, Eun-Bee Lee, Jong-Pil Seo","doi":"10.4142/jvs.25252","DOIUrl":"10.4142/jvs.25252","url":null,"abstract":"Importance: The use of combinations of sedative and analgesic drugs during standing procedures in horses is necessary to provide reliable sedation with minimal ataxia and reduced responses to surgical or other stimuli in horses.Objective: This study assessed the behavioral and cardiorespiratory effects of medetomidine (M) administered with and without tramadol (T) in horses.Methods: Eight horses were sedated intravenously with M (5 µg/kg) alone or with T (2 mg/kg) in a arandomized, blind, two-way crossover trial. Behavioral responses, including head height above the ground (HHAG), postural instability (PI), and response to pressure stimulus (RPS), and cardiorespiratory responses, including vital variables and blood analyses, were assessed following administration.Results: There were no clinically meaningful differences in cardiorespiratory values, HHAG, or PI between the groups. The RPS score over the scapula was significantly higher in the medetomidine and tramadol (MT) group (p < 0.05) and a trend towards a higher RPS score over the femur was observed (p = 0.08) in the MT group. Heart rate decreased significantly below baseline from 10 to 40 min in both treatments.Conclusions and relevance: These results suggest that the MT combination may provide sufficient sedation and analgesia with minimal cardiorespiratory changes in horses.","PeriodicalId":17557,"journal":{"name":"Journal of Veterinary Science","volume":"27 2","pages":"e17"},"PeriodicalIF":1.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13062433/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147633517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Use of MAVRIC-SL for metal artifact reduction in postoperative canine stifle MRI. MAVRIC-SL用于犬膝关节术后MRI金属伪影复位。

IF 1.5 3区农林科学

Journal of Veterinary Science Pub Date : 2026-03-01 DOI: 10.4142/jvs.25182

Sojin Kim, Youngmin Kim, Jae-Pung Han, Sunghoon Jeon, Gonhyung Kim, Sang-Hwan Hyun, Dongwoo Chang, Namsoon Lee

{"title":"Use of MAVRIC-SL for metal artifact reduction in postoperative canine stifle MRI.","authors":"Sojin Kim, Youngmin Kim, Jae-Pung Han, Sunghoon Jeon, Gonhyung Kim, Sang-Hwan Hyun, Dongwoo Chang, Namsoon Lee","doi":"10.4142/jvs.25182","DOIUrl":"10.4142/jvs.25182","url":null,"abstract":"Importance: Cranial cruciate ligament rupture (CCLR) is a common cause of pelvic limb lameness in dogs. Surgical correction using metallic implants is commonly performed; however, using postoperative magnetic resonance imaging (MRI) for evaluation is limited owing to susceptibility artifacts.Objective: This study aimed to determine whether a multiacquisition variable-resonance image combination-selective (MAVRIC-SL) sequence, which reduces susceptibility artifacts, is useful for postoperative evaluation.Methods: MRI was performed on four dogs that underwent CCLR correction using metallic implants. Imaging was performed with MAVRIC-SL and two-dimensional fast spin echo (2D-FSE) sequences, including proton density (PD), PD fat-suppressed (F/S), and T2-weighted F/S. The artifact area for each sequence was quantitatively analyzed. A four-level qualitative image analysis was performed to assess image artifacts, cartilage delineation, and visualization of the cranial cruciate ligament and bone.Results: The artifact area was significantly reduced with MAVRIC-SL than with 2D-FSE, regardless of the metal materials used. In addition, the amount of artifact, cartilage delineation, and visualization of the bone were significantly improved with MAVRIC-SL compared with 2D-FSE.Conclusions and relevance: In this preliminary study, the MAVRIC-SL sequence improves postoperative MRI evaluation by reducing susceptibility artifacts in dogs with CCLR treated with metallic implants.","PeriodicalId":17557,"journal":{"name":"Journal of Veterinary Science","volume":"27 2","pages":"e21"},"PeriodicalIF":1.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13062429/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147633668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between chronic kidney disease progression and serum feline pancreatic lipase concentrations in cats. 慢性肾脏疾病进展与猫血清胰脂肪酶浓度之间的关系。

IF 1.5 3区农林科学

Journal of Veterinary Science Pub Date : 2026-03-01 DOI: 10.4142/jvs.25273

Jihyun Kim, Youngmin Yun

{"title":"Association between chronic kidney disease progression and serum feline pancreatic lipase concentrations in cats.","authors":"Jihyun Kim, Youngmin Yun","doi":"10.4142/jvs.25273","DOIUrl":"10.4142/jvs.25273","url":null,"abstract":"Importance: Serum feline pancreatic lipase (fPL) is used to diagnose pancreatitis, but interpretation is challenging because fPL may be affected by non-pancreatic disease, including reduced renal function.Objective: To evaluate the association between chronic kidney disease (CKD) stage and serum fPL in cats and characterize how renal biomarkers relate to fPL.Methods: This retrospective study evaluated medical records of cats presented to a secondary referral veterinary hospital between February 2024 and March 2025. Inclusion required same-day testing of complete blood count, serum biochemistry, blood gas analysis, urinalysis, serum fPL, and abdominal ultrasonography. CKD staging followed International Renal Interest Society guidelines using serum creatinine, urine specific gravity (USG), and ultrasonography. Nonparametric group comparisons were performed using the Kruskal-Wallis test, and associations between fPL and renal biomarkers were assessed using Spearman's correlation.Results: fPL increased significantly with advancing CKD stage (p < 0.001). Furthermore, fPL was positively correlated with blood urea nitrogen (ρ = 0.516, p < 0.001), creatinine (ρ = 0.459, p < 0.001), and inorganic phosphorus (ρ = 0.312, p < 0.001). Additionally, fPL and USG exhibited an inverse correlation (ρ = -0.502, p < 0.001). Ionized calcium showed no correlation with fPL (ρ = 0.012, p = 0.898).Conclusions and relevance: In this clinical cohort, higher CKD stage was associated with higher serum fPL. Because fPL alone is insufficient to diagnose pancreatitis and may increase with reduced renal function, mild-to-moderate fPL elevations in cats with CKD should be interpreted in the context of clinical signs and pancreatic imaging findings.","PeriodicalId":17557,"journal":{"name":"Journal of Veterinary Science","volume":"27 2","pages":"e30"},"PeriodicalIF":1.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13062426/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147633303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0