K.L. Walker, Y. Thomas, S. Arif, S. Samer, C. Rische, R. Krier, J.A. O’Sullivan, R.L. Redondo, A.M. Carias, T. Russo, M. McRaven, E. Allen, C.T. Thuruthiyil, F. Engleman, E. Martinelli, F. Villinger, B. Bochner, T.J. Hope
{"title":"PP1.4 – 00138 SIV and HIV Infection of Mast Cells","authors":"K.L. Walker, Y. Thomas, S. Arif, S. Samer, C. Rische, R. Krier, J.A. O’Sullivan, R.L. Redondo, A.M. Carias, T. Russo, M. McRaven, E. Allen, C.T. Thuruthiyil, F. Engleman, E. Martinelli, F. Villinger, B. Bochner, T.J. Hope","doi":"10.1016/j.jve.2024.100453","DOIUrl":"10.1016/j.jve.2024.100453","url":null,"abstract":"","PeriodicalId":17552,"journal":{"name":"Journal of Virus Eradication","volume":"10 ","pages":"Pages 41-42"},"PeriodicalIF":3.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143181386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J.H. McMahon, J.S.Y. Lau, L. Wallace, M. Kaiser, J. Chang, A. Solomon, B. Scher, P. Beech, D. Price, T.A. Rasmussen, S.R. Lewin
{"title":"7.1 – 00113 Safety and PD-1 receptor occupancy with low dose Nivolumab in adults living with HIV on antiretroviral therapy: NIVO-LD","authors":"J.H. McMahon, J.S.Y. Lau, L. Wallace, M. Kaiser, J. Chang, A. Solomon, B. Scher, P. Beech, D. Price, T.A. Rasmussen, S.R. Lewin","doi":"10.1016/j.jve.2024.100430","DOIUrl":"10.1016/j.jve.2024.100430","url":null,"abstract":"","PeriodicalId":17552,"journal":{"name":"Journal of Virus Eradication","volume":"10 ","pages":"Pages 24-25"},"PeriodicalIF":3.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143180799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Chen, X. Li, V.R. Chirasani, K.J. Bar, S. Gianella, D.M. Margolis, Y. Tang, G. Jiang
{"title":"PP2.1 – 00175 HIV genome derived from the brain microglia isolated from PWH on ART","authors":"H. Chen, X. Li, V.R. Chirasani, K.J. Bar, S. Gianella, D.M. Margolis, Y. Tang, G. Jiang","doi":"10.1016/j.jve.2024.100471","DOIUrl":"10.1016/j.jve.2024.100471","url":null,"abstract":"","PeriodicalId":17552,"journal":{"name":"Journal of Virus Eradication","volume":"10 ","pages":"Pages 53-54"},"PeriodicalIF":3.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143180587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"PP4.4 – 00151 Trained immunity as an exacerbating factor in Chronic HIV and HIVAssociated Neurocognitive Disorders","authors":"Z. Capriotti, C. Wallace, R. Van Duyne, Z. Klase","doi":"10.1016/j.jve.2024.100491","DOIUrl":"10.1016/j.jve.2024.100491","url":null,"abstract":"","PeriodicalId":17552,"journal":{"name":"Journal of Virus Eradication","volume":"10 ","pages":"Pages 65-66"},"PeriodicalIF":3.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143180198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"PP1.19 – 00036 Unexpected Redundancy of the TNF/NF-kB Axis in HIV-1 Restriction and Latency Reversal in Primary Human MDM Polarized to M1 Cells","authors":"G. Poli, I. Pagani, S. Ghezzi, E. Vicenzi","doi":"10.1016/j.jve.2024.100468","DOIUrl":"10.1016/j.jve.2024.100468","url":null,"abstract":"","PeriodicalId":17552,"journal":{"name":"Journal of Virus Eradication","volume":"10 ","pages":"Page 52"},"PeriodicalIF":3.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143180590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Remesal González, S. Rodriguez-Mora, R. González-Soltero, M. Torres, M. Coiras
{"title":"PP1.10 – 00098 Gene expression dynamics following dasatinib treatment and discontinuation in people with HIV-1: case report","authors":"M. Remesal González, S. Rodriguez-Mora, R. González-Soltero, M. Torres, M. Coiras","doi":"10.1016/j.jve.2024.100459","DOIUrl":"10.1016/j.jve.2024.100459","url":null,"abstract":"","PeriodicalId":17552,"journal":{"name":"Journal of Virus Eradication","volume":"10 ","pages":"Page 46"},"PeriodicalIF":3.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143181428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Dunn, J. Malgady, B. Lima, J.M. Crater, P.M. Del Río Estrada, M.F. Torres-Ruiz, Y.A. Luna-Villalobos, M. González-Navarro, C. Kovacs, C. Kang, D. Mullins, P. Jolicoeur, S. Ávila-Ríos, D.F. Nixon, R.L. Furler O’Brien
{"title":"PP1.2 – 00165 Inhibition of ARP2/3 by HIV Nef Leads to Impaired CD4+ T Cell Function & Dysregulation of Immunity within Progressors but not all HIV Controllers","authors":"D. Dunn, J. Malgady, B. Lima, J.M. Crater, P.M. Del Río Estrada, M.F. Torres-Ruiz, Y.A. Luna-Villalobos, M. González-Navarro, C. Kovacs, C. Kang, D. Mullins, P. Jolicoeur, S. Ávila-Ríos, D.F. Nixon, R.L. Furler O’Brien","doi":"10.1016/j.jve.2024.100451","DOIUrl":"10.1016/j.jve.2024.100451","url":null,"abstract":"","PeriodicalId":17552,"journal":{"name":"Journal of Virus Eradication","volume":"10 ","pages":"Pages 39-40"},"PeriodicalIF":3.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143179366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Skinner, Z. Quinn, I. Gorrell-Brown, M. Rollins, L. Thron, A. Acharya, E. Sempek, D. Dawn, M. Reynolds, S. Byrareddy, L. Ndhlovu, V. Vezys, M. Pampusch
{"title":"6.6 – 00176 CAR/CCR9 T cell immunotherapy shows promise in localization of SIV-specific CAR T cells to the gastrointestinal tract of rhesus macaques","authors":"P. Skinner, Z. Quinn, I. Gorrell-Brown, M. Rollins, L. Thron, A. Acharya, E. Sempek, D. Dawn, M. Reynolds, S. Byrareddy, L. Ndhlovu, V. Vezys, M. Pampusch","doi":"10.1016/j.jve.2024.100429","DOIUrl":"10.1016/j.jve.2024.100429","url":null,"abstract":"","PeriodicalId":17552,"journal":{"name":"Journal of Virus Eradication","volume":"10 ","pages":"Pages 23-24"},"PeriodicalIF":3.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143128874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maaike A.J. Noorman , John B.F. de Wit , Tamika A. Marcos , Sarah E. Stutterheim , Thijs Albers , Kai J. Jonas , Chantal den Daas
{"title":"Relatively high interest but limited active engagement in HIV cure research: Awareness, interest, and information-seeking among affected communities in the Netherlands","authors":"Maaike A.J. Noorman , John B.F. de Wit , Tamika A. Marcos , Sarah E. Stutterheim , Thijs Albers , Kai J. Jonas , Chantal den Daas","doi":"10.1016/j.jve.2024.100570","DOIUrl":"10.1016/j.jve.2024.100570","url":null,"abstract":"<div><h3>Background</h3><div>Community engagement is important for inclusive HIV cure development. This study evaluates current engagement in HIV cure research among affected communities in the Netherlands by analyzing awareness, interest, and information-seeking behavior. It also identifies participant characteristics and HIV-related illness perceptions linked to each engagement stage.</div></div><div><h3>Methods</h3><div>A cross-sectional survey was conducted from July 2023 to March 2024, involving 499 people with HIV and 578 individuals without HIV, including partners and gay, bisexual, and other men who have sex with men. Multivariate regression analyses examined the relationships between participant characteristics, HIV-related illness perceptions, and three outcomes: awareness, interest, and information-seeking.</div></div><div><h3>Results</h3><div>The mean awareness was 3.08 (SD = 0.99) interest was higher at 3.67 (SD = 0.85), while the information-seeking frequency was lower at 2.33 (SD = 0.97). Higher awareness was seen in older participants, non-cisgender men, and those with increased perceived control and comprehensibility of HIV. Interest in cure research was higher among people with HIV, those with a migration background, individuals with steady partner(s), and those experiencing greater HIV-related concerns, negative HIV-related emotions, and better HIV comprehension. Information-seeking frequency was greater among people with HIV, those with a bachelor's degree, individuals from a migration background, those with steady partner(s), and those perceiving more severe HIV-related symptoms, and heightened concerns and negative emotions about HIV.</div></div><div><h3>Conclusion</h3><div>While moderate awareness exists, engagement remains passive with limited information-seeking; however, significant interest in a cure underscores the need for enhanced communication efforts to foster inclusive HIV cure development.</div></div>","PeriodicalId":17552,"journal":{"name":"Journal of Virus Eradication","volume":"10 4","pages":"Article 100570"},"PeriodicalIF":3.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11697764/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142932015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}