Journal of Virus Eradication最新文献

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PP1.4 – 00138 SIV and HIV Infection of Mast Cells SIV与肥大细胞HIV感染
IF 3.5 4区 医学
Journal of Virus Eradication Pub Date : 2024-12-01 DOI: 10.1016/j.jve.2024.100453
K.L. Walker, Y. Thomas, S. Arif, S. Samer, C. Rische, R. Krier, J.A. O’Sullivan, R.L. Redondo, A.M. Carias, T. Russo, M. McRaven, E. Allen, C.T. Thuruthiyil, F. Engleman, E. Martinelli, F. Villinger, B. Bochner, T.J. Hope
{"title":"PP1.4 – 00138 SIV and HIV Infection of Mast Cells","authors":"K.L. Walker, Y. Thomas, S. Arif, S. Samer, C. Rische, R. Krier, J.A. O’Sullivan, R.L. Redondo, A.M. Carias, T. Russo, M. McRaven, E. Allen, C.T. Thuruthiyil, F. Engleman, E. Martinelli, F. Villinger, B. Bochner, T.J. Hope","doi":"10.1016/j.jve.2024.100453","DOIUrl":"10.1016/j.jve.2024.100453","url":null,"abstract":"","PeriodicalId":17552,"journal":{"name":"Journal of Virus Eradication","volume":"10 ","pages":"Pages 41-42"},"PeriodicalIF":3.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143181386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
7.1 – 00113 Safety and PD-1 receptor occupancy with low dose Nivolumab in adults living with HIV on antiretroviral therapy: NIVO-LD 7.1 - 00113 低剂量 Nivolumab 用于接受抗逆转录病毒治疗的成年 HIV 感染者的安全性和 PD-1 受体占用率:NIVO-LD
IF 3.5 4区 医学
Journal of Virus Eradication Pub Date : 2024-12-01 DOI: 10.1016/j.jve.2024.100430
J.H. McMahon, J.S.Y. Lau, L. Wallace, M. Kaiser, J. Chang, A. Solomon, B. Scher, P. Beech, D. Price, T.A. Rasmussen, S.R. Lewin
{"title":"7.1 – 00113 Safety and PD-1 receptor occupancy with low dose Nivolumab in adults living with HIV on antiretroviral therapy: NIVO-LD","authors":"J.H. McMahon, J.S.Y. Lau, L. Wallace, M. Kaiser, J. Chang, A. Solomon, B. Scher, P. Beech, D. Price, T.A. Rasmussen, S.R. Lewin","doi":"10.1016/j.jve.2024.100430","DOIUrl":"10.1016/j.jve.2024.100430","url":null,"abstract":"","PeriodicalId":17552,"journal":{"name":"Journal of Virus Eradication","volume":"10 ","pages":"Pages 24-25"},"PeriodicalIF":3.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143180799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PP2.1 – 00175 HIV genome derived from the brain microglia isolated from PWH on ART PP2.1 - 00175 HIV基因组来源于接受抗逆转录病毒治疗的PWH分离的脑小胶质细胞
IF 3.5 4区 医学
Journal of Virus Eradication Pub Date : 2024-12-01 DOI: 10.1016/j.jve.2024.100471
H. Chen, X. Li, V.R. Chirasani, K.J. Bar, S. Gianella, D.M. Margolis, Y. Tang, G. Jiang
{"title":"PP2.1 – 00175 HIV genome derived from the brain microglia isolated from PWH on ART","authors":"H. Chen, X. Li, V.R. Chirasani, K.J. Bar, S. Gianella, D.M. Margolis, Y. Tang, G. Jiang","doi":"10.1016/j.jve.2024.100471","DOIUrl":"10.1016/j.jve.2024.100471","url":null,"abstract":"","PeriodicalId":17552,"journal":{"name":"Journal of Virus Eradication","volume":"10 ","pages":"Pages 53-54"},"PeriodicalIF":3.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143180587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PP4.4 – 00151 Trained immunity as an exacerbating factor in Chronic HIV and HIVAssociated Neurocognitive Disorders 训练免疫是慢性HIV和HIV相关神经认知障碍的加重因素
IF 3.5 4区 医学
Journal of Virus Eradication Pub Date : 2024-12-01 DOI: 10.1016/j.jve.2024.100491
Z. Capriotti, C. Wallace, R. Van Duyne, Z. Klase
{"title":"PP4.4 – 00151 Trained immunity as an exacerbating factor in Chronic HIV and HIVAssociated Neurocognitive Disorders","authors":"Z. Capriotti, C. Wallace, R. Van Duyne, Z. Klase","doi":"10.1016/j.jve.2024.100491","DOIUrl":"10.1016/j.jve.2024.100491","url":null,"abstract":"","PeriodicalId":17552,"journal":{"name":"Journal of Virus Eradication","volume":"10 ","pages":"Pages 65-66"},"PeriodicalIF":3.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143180198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PP1.19 – 00036 Unexpected Redundancy of the TNF/NF-kB Axis in HIV-1 Restriction and Latency Reversal in Primary Human MDM Polarized to M1 Cells TNF/NF-kB轴在HIV-1限制和原发性人MDM向M1细胞极化的潜伏期逆转中的意外冗余
IF 3.5 4区 医学
Journal of Virus Eradication Pub Date : 2024-12-01 DOI: 10.1016/j.jve.2024.100468
G. Poli, I. Pagani, S. Ghezzi, E. Vicenzi
{"title":"PP1.19 – 00036 Unexpected Redundancy of the TNF/NF-kB Axis in HIV-1 Restriction and Latency Reversal in Primary Human MDM Polarized to M1 Cells","authors":"G. Poli, I. Pagani, S. Ghezzi, E. Vicenzi","doi":"10.1016/j.jve.2024.100468","DOIUrl":"10.1016/j.jve.2024.100468","url":null,"abstract":"","PeriodicalId":17552,"journal":{"name":"Journal of Virus Eradication","volume":"10 ","pages":"Page 52"},"PeriodicalIF":3.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143180590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PP1.10 – 00098 Gene expression dynamics following dasatinib treatment and discontinuation in people with HIV-1: case report 达沙替尼治疗和停药后HIV-1患者的基因表达动态:病例报告
IF 3.5 4区 医学
Journal of Virus Eradication Pub Date : 2024-12-01 DOI: 10.1016/j.jve.2024.100459
M. Remesal González, S. Rodriguez-Mora, R. González-Soltero, M. Torres, M. Coiras
{"title":"PP1.10 – 00098 Gene expression dynamics following dasatinib treatment and discontinuation in people with HIV-1: case report","authors":"M. Remesal González, S. Rodriguez-Mora, R. González-Soltero, M. Torres, M. Coiras","doi":"10.1016/j.jve.2024.100459","DOIUrl":"10.1016/j.jve.2024.100459","url":null,"abstract":"","PeriodicalId":17552,"journal":{"name":"Journal of Virus Eradication","volume":"10 ","pages":"Page 46"},"PeriodicalIF":3.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143181428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PP2.3 – 00168 Blocks to HIV transcriptional initiation, elongation, and splicing contribute differentially to inefficient virus reactivation across authentic reservoir-harboring CD4+ T-cell clones PP2.3 - 00168对HIV转录起始、延伸和剪接的阻断不同程度地促进了病毒在真实的库藏CD4+ t细胞克隆中的低效再激活
IF 3.5 4区 医学
Journal of Virus Eradication Pub Date : 2024-12-01 DOI: 10.1016/j.jve.2024.100473
T. Huynh, I. Ferreira, A. Herreira, E. Stone, N. Linden, M. Caskey, C. Bittar, M.C. Nussenzweig, B. Jones
{"title":"PP2.3 – 00168 Blocks to HIV transcriptional initiation, elongation, and splicing contribute differentially to inefficient virus reactivation across authentic reservoir-harboring CD4+ T-cell clones","authors":"T. Huynh, I. Ferreira, A. Herreira, E. Stone, N. Linden, M. Caskey, C. Bittar, M.C. Nussenzweig, B. Jones","doi":"10.1016/j.jve.2024.100473","DOIUrl":"10.1016/j.jve.2024.100473","url":null,"abstract":"","PeriodicalId":17552,"journal":{"name":"Journal of Virus Eradication","volume":"10 ","pages":"Page 55"},"PeriodicalIF":3.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143178209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PP1.2 – 00165 Inhibition of ARP2/3 by HIV Nef Leads to Impaired CD4+ T Cell Function & Dysregulation of Immunity within Progressors but not all HIV Controllers HIV Nef抑制ARP2/3导致进展者体内CD4+ T细胞功能受损和免疫失调,但并非所有HIV控制者
IF 3.5 4区 医学
Journal of Virus Eradication Pub Date : 2024-12-01 DOI: 10.1016/j.jve.2024.100451
D. Dunn, J. Malgady, B. Lima, J.M. Crater, P.M. Del Río Estrada, M.F. Torres-Ruiz, Y.A. Luna-Villalobos, M. González-Navarro, C. Kovacs, C. Kang, D. Mullins, P. Jolicoeur, S. Ávila-Ríos, D.F. Nixon, R.L. Furler O’Brien
{"title":"PP1.2 – 00165 Inhibition of ARP2/3 by HIV Nef Leads to Impaired CD4+ T Cell Function & Dysregulation of Immunity within Progressors but not all HIV Controllers","authors":"D. Dunn, J. Malgady, B. Lima, J.M. Crater, P.M. Del Río Estrada, M.F. Torres-Ruiz, Y.A. Luna-Villalobos, M. González-Navarro, C. Kovacs, C. Kang, D. Mullins, P. Jolicoeur, S. Ávila-Ríos, D.F. Nixon, R.L. Furler O’Brien","doi":"10.1016/j.jve.2024.100451","DOIUrl":"10.1016/j.jve.2024.100451","url":null,"abstract":"","PeriodicalId":17552,"journal":{"name":"Journal of Virus Eradication","volume":"10 ","pages":"Pages 39-40"},"PeriodicalIF":3.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143179366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
6.6 – 00176 CAR/CCR9 T cell immunotherapy shows promise in localization of SIV-specific CAR T cells to the gastrointestinal tract of rhesus macaques CAR/CCR9 T细胞免疫疗法有望将siv特异性CAR - T细胞定位到恒河猴的胃肠道
IF 3.5 4区 医学
Journal of Virus Eradication Pub Date : 2024-12-01 DOI: 10.1016/j.jve.2024.100429
P. Skinner, Z. Quinn, I. Gorrell-Brown, M. Rollins, L. Thron, A. Acharya, E. Sempek, D. Dawn, M. Reynolds, S. Byrareddy, L. Ndhlovu, V. Vezys, M. Pampusch
{"title":"6.6 – 00176 CAR/CCR9 T cell immunotherapy shows promise in localization of SIV-specific CAR T cells to the gastrointestinal tract of rhesus macaques","authors":"P. Skinner, Z. Quinn, I. Gorrell-Brown, M. Rollins, L. Thron, A. Acharya, E. Sempek, D. Dawn, M. Reynolds, S. Byrareddy, L. Ndhlovu, V. Vezys, M. Pampusch","doi":"10.1016/j.jve.2024.100429","DOIUrl":"10.1016/j.jve.2024.100429","url":null,"abstract":"","PeriodicalId":17552,"journal":{"name":"Journal of Virus Eradication","volume":"10 ","pages":"Pages 23-24"},"PeriodicalIF":3.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143128874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relatively high interest but limited active engagement in HIV cure research: Awareness, interest, and information-seeking among affected communities in the Netherlands 对艾滋病毒治疗研究的兴趣相对较高,但积极参与有限:荷兰受影响社区的认识、兴趣和信息寻求。
IF 3.5 4区 医学
Journal of Virus Eradication Pub Date : 2024-12-01 DOI: 10.1016/j.jve.2024.100570
Maaike A.J. Noorman , John B.F. de Wit , Tamika A. Marcos , Sarah E. Stutterheim , Thijs Albers , Kai J. Jonas , Chantal den Daas
{"title":"Relatively high interest but limited active engagement in HIV cure research: Awareness, interest, and information-seeking among affected communities in the Netherlands","authors":"Maaike A.J. Noorman ,&nbsp;John B.F. de Wit ,&nbsp;Tamika A. Marcos ,&nbsp;Sarah E. Stutterheim ,&nbsp;Thijs Albers ,&nbsp;Kai J. Jonas ,&nbsp;Chantal den Daas","doi":"10.1016/j.jve.2024.100570","DOIUrl":"10.1016/j.jve.2024.100570","url":null,"abstract":"<div><h3>Background</h3><div>Community engagement is important for inclusive HIV cure development. This study evaluates current engagement in HIV cure research among affected communities in the Netherlands by analyzing awareness, interest, and information-seeking behavior. It also identifies participant characteristics and HIV-related illness perceptions linked to each engagement stage.</div></div><div><h3>Methods</h3><div>A cross-sectional survey was conducted from July 2023 to March 2024, involving 499 people with HIV and 578 individuals without HIV, including partners and gay, bisexual, and other men who have sex with men. Multivariate regression analyses examined the relationships between participant characteristics, HIV-related illness perceptions, and three outcomes: awareness, interest, and information-seeking.</div></div><div><h3>Results</h3><div>The mean awareness was 3.08 (SD = 0.99) interest was higher at 3.67 (SD = 0.85), while the information-seeking frequency was lower at 2.33 (SD = 0.97). Higher awareness was seen in older participants, non-cisgender men, and those with increased perceived control and comprehensibility of HIV. Interest in cure research was higher among people with HIV, those with a migration background, individuals with steady partner(s), and those experiencing greater HIV-related concerns, negative HIV-related emotions, and better HIV comprehension. Information-seeking frequency was greater among people with HIV, those with a bachelor's degree, individuals from a migration background, those with steady partner(s), and those perceiving more severe HIV-related symptoms, and heightened concerns and negative emotions about HIV.</div></div><div><h3>Conclusion</h3><div>While moderate awareness exists, engagement remains passive with limited information-seeking; however, significant interest in a cure underscores the need for enhanced communication efforts to foster inclusive HIV cure development.</div></div>","PeriodicalId":17552,"journal":{"name":"Journal of Virus Eradication","volume":"10 4","pages":"Article 100570"},"PeriodicalIF":3.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11697764/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142932015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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