Journal of vascular surgery. Venous and lymphatic disorders最新文献

{"title":"Targeted therapy guided by photon-counting computed tomography in Klippel-Trénaunay syndrome.","authors":"Wenli Jiang, Xin Wei, Zhiming Zhou","doi":"10.1016/j.jvsv.2026.102501","DOIUrl":"10.1016/j.jvsv.2026.102501","url":null,"abstract":"","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":" ","pages":"102501"},"PeriodicalIF":2.8,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147717185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Open surgery appears to be the preferred treatment in patients with nutcracker syndrome: A vascular low frequency disease consortium analysis.","authors":"Bjoern D Suckow, Aravind Ponukumati, Lily Wang, Jesse Columbo, David Stone, Richard Powell, Lauren N West-Livingston, Cynthia K Shortell, Yana Etkin, Samuel P R Paci, Jake F Hemingway, Mark H Meissner, Clara M Gomez-Sanchez, Collen P Flanagan, Paul G Bove, Graham W Long, Brigitte K Smith, Alexander Gombert, Mohammad Esmaeil Barbati, Bernadette Aulivola, Francesco Stilo, Nunzio Montelione, Giovanni De Caridi, Filippo Benedetto, Katharine L McGinigle, Mohammad Alsaarayreh, Zoltan Szeberin, Dora Z Zatyko, Kwame S Amankwah, Jin Hyun Joh, Sungsin Cho, Marc L Schermerhorn, Sai Divya Yadavalli, Wei Zhou, Jeffrey Tolson, Peter Lawrence, Karen Woo","doi":"10.1016/j.jvsv.2026.102497","DOIUrl":"10.1016/j.jvsv.2026.102497","url":null,"abstract":"<p><strong>Objectives: </strong>Nutcracker syndrome (NCS) is an uncommon vascular disease, characterized by anatomical compression of the left renal vein (LRV). Associated symptoms include flank and pelvic pain, as well as hematuria and varicocele. Our objective was to examine the contemporary management of NCS including diagnostic workup for and outcomes of nonoperative and operative treatments.</p><p><strong>Methods: </strong>Patients diagnosed with NCS between 2000 and 2024 were identified through the Vascular Low Frequency Disease Consortium. Demographic, diagnostic, and treatment modalities were reported, including primary and secondary patency, reintervention, and symptom resolution/recurrence. Patient characteristics were reported using descriptive statistics and Kaplan-Meier analysis was used to report outcomes.</p><p><strong>Results: </strong>NCS was diagnosed in 250 patients at 17 institutions. The mean patient age at diagnosis was 37 ± 15 years, 90% were female, and 83% were White. Presenting symptoms and findings included nonpositional flank pain (58%), chronic pelvic pain/dyspareunia (49%), hematuria (48%), nonpositional abdominal pain (47%), and varicocele (3.3%). Diagnostic workup of NCS included computed tomography scan of the abdomen/pelvis (84%), venogram (63%), duplex ultrasound examination (35%), and magnetic resonance imaging (17%). Imaging demonstrated a mean aortosuperior mesenteric artery angle of 27.7°. On duplex ultrasound examination, the mean peak systolic velocity of the LRV was 108.9 ± 99.0 cm/s at the compression point and 21.7 ± 9.5 cm/s at the hilum, with a peak systolic velocity ratio of 4.98, whereas venography demonstrated a mean renocaval pressure gradient of 3.92 ± 2.40 mm Hg. Nonoperative treatment with oral analgesics (29%), nutritional counseling/feeding regimen (16%), or simple expectant management (55%) was used in 116 patients and successful in 90 patients (78%) with a mean follow-up of 328 days. Indications for nonoperative management included mild symptoms (64%), young age (10%), and patient preference (8.4%). Of the 26 patients (22%) who failed nonoperative treatment, 20 were subsequently managed with surgery. In the 134 patients who underwent surgery, either as initial treatment or after nonoperative failure, 60 (44%) had a LRV transposition, 43 (31%) underwent a gonadal/ovarian vein transposition, 18 (12%) underwent renal autotransplantation, and 19 (13%) underwent endovascular therapy. The overall 3-year primary patency and secondary patency were 65% (95% confidence interval [CI], 51-76) and 96% (95% CI, 88-99), respectively. The 3-year freedom from reintervention and symptom recurrence were 67% (95% CI, 53-78) and 60% (95% CI, 48-70), respectively. Patients who underwent endovascular intervention had inferior primary patency and freedom from symptom recurrence: 35% (95% CI, 1.22-78) and 46% (95% CI, 7.99-79), respectively.</p><p><strong>Conclusions: </strong>Approximately 20% of patients with NCS","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":" ","pages":"102497"},"PeriodicalIF":2.8,"publicationDate":"2026-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147690995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of concomitant deep vein thrombosis on outcomes of acute pulmonary embolism: Insights from the PERT consortium registry.","authors":"Ka U Lio, Wissam A Jaber, Sanjum Sethi, Steven Horbal, Belinda N Rivera-Lebron, Rachel P Rosovsky, Charles B Ross, Eric Secemsky, Parth Rali","doi":"10.1016/j.jvsv.2026.102499","DOIUrl":"10.1016/j.jvsv.2026.102499","url":null,"abstract":"<p><strong>Objective: </strong>Studies have reported conflicting data regarding the prognostic significance of concomitant deep vein thrombosis (DVT) in acute pulmonary embolism (PE). Understanding the potential differences between PE with and without DVT is crucial for optimizing strategies.</p><p><strong>Methods: </strong>Using data from The Pulmonary Embolism Response Teams Consortium Registry, this study examined the association between concomitant DVT and clinical outcomes in patients with predominantly acute intermediate- and high-risk PE. A secondary aim was to assess the impact of DVT on treatment selection, particularly the use of advanced therapies.</p><p><strong>Results: </strong>Among 7346 patients with acute PE, 5076 (69%) had concomitant DVT. Patients with DVT were more frequently classified as intermediate-risk compared with patients without DVT, including intermediate-high (59.31% vs 51.9%; P < .001) and intermediate-low risk PE (19.4% vs 17.7%; P < .001). The presence of DVT was significantly associated with higher odds of receiving advanced therapies (odds ratio [OR], 2.49; 95% confidence interval [CI], 2.14-2.81), particularly catheter-directed therapy (OR, 2.44; 95% CI, 2.12-2.83), with the strongest association observed in the intermediate- to high-risk group (OR, 2.67; 95% CI, 2.25-3.18). Concomitant proximal DVT was not associated with increased in-hospital mortality (OR, 0.87; 95% CI, 0.69-1.09), 30-day mortality (OR, 0.96; 95% CI, 0.77-1.20), 1-year mortality (OR, 0.87; 95% CI, 0.73-1.03), or intensive care unit admission (OR, 1.05; 95% CI, 0.93-1.20), after adjustment for advanced therapy use.</p><p><strong>Conclusions: </strong>In this large contemporary cohort of predominantly intermediate- and high-risk PE, concomitant DVT was common and associated with more severe presentation and greater use of advanced therapies, but not with higher short- or long-term mortality.</p>","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":" ","pages":"102499"},"PeriodicalIF":2.8,"publicationDate":"2026-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147691001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The continuing challenge of Nutcracker syndrome.","authors":"Peter Gloviczki","doi":"10.1016/j.jvsv.2026.102498","DOIUrl":"10.1016/j.jvsv.2026.102498","url":null,"abstract":"","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":" ","pages":"102498"},"PeriodicalIF":2.8,"publicationDate":"2026-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147674549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of ovarian vein embolization alone with pelvic venous plexus embolization in the treatment of pelvic venous disorders at 12-month follow-up.","authors":"Haluk Caglar Karakaya, Cem Ariturk","doi":"10.1016/j.jvsv.2026.102502","DOIUrl":"10.1016/j.jvsv.2026.102502","url":null,"abstract":"<p><strong>Objective: </strong>Percutaneous endovenous embolization has emerged as a treatment of choice for nonobstructive pelvic venous disorders (PeVD) due to its effectiveness, ease of application, and less invasiveness compared with surgical interventions. In this study, we aimed to analyze 12-month outcomes of the pelvic venous plexus embolization (PVPE) approach and the ovarian vein embolization alone (OVEA) approach.</p><p><strong>Methods: </strong>This retrospective cohort included 72 women with PeVD who underwent percutaneous endovenous embolization between 2022 and 2024. Patients were assigned to OVEA or PVPE. Symptoms such as chronic pelvic pain, dyspareunia, postcoital pain, and dysmenorrhea were assessed using the visual analog scale at baseline and 12 months. Bladder symptoms were recorded as present/absent. Recurrence was defined as reappearance or worsening of symptoms within 12 months postprocedure. The primary outcome was 12-month symptom relief; secondary outcomes were recurrence and complications.</p><p><strong>Results: </strong>Technical success rate was 100%. Visual analog scale scores for chronic pelvic pain, dyspareunia, and postcoital pain at the 12th month were significantly lower in the PVPE group compared with OVEA (P = .001, P = .008, and P = .005, respectively). Recurrence was statistically significantly lower in two patients in the PVPE group compared with nine patients in the OVEA group (P = .036). The mean diagnosis time was found to be 34.98 ± 9.03 months.</p><p><strong>Conclusions: </strong>PeVD is a heterogeneous clinical condition in which both venous reflux and venous outflow obstruction may contribute to symptom development. Our study demonstrated that, in patients with nonobstructive PeVD, the PVPE approach may provide better symptomatic relief and reduced recurrence rates. Long-term results of this approach should be supported by further studies to reach a more solid scientific basis for the management of PeVD.</p>","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":" ","pages":"102502"},"PeriodicalIF":2.8,"publicationDate":"2026-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147674538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Randomized, Open-label Pilot Trial of Clopidogrel vs No Treatment After Iliac Vein Stenting for NIVLs","authors":"Olga Bakayev MD ,&nbsp;Iryna Kuzma MD ,&nbsp;Enrico Ascher MD ,&nbsp;Anil Hingorani MD","doi":"10.1016/j.jvsv.2025.102422","DOIUrl":"10.1016/j.jvsv.2025.102422","url":null,"abstract":"","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"14 2","pages":"Article 102422"},"PeriodicalIF":2.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147394104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Events of Interest","authors":"","doi":"10.1016/S2213-333X(26)00013-2","DOIUrl":"10.1016/S2213-333X(26)00013-2","url":null,"abstract":"","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"14 2","pages":"Article 102454"},"PeriodicalIF":2.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147394106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exercise Programs in the Management of Venous Leg Ulceration—A Systematic Review and Meta-analysis","authors":"Anselmo Pagani Msc ,&nbsp;Matthew Tan MBBS, BSc(Hons), MRCS, AFHEA ,&nbsp;Sarah Onida BSc, MBBS, MRCS, PhD ,&nbsp;Alun Davies DM, FRCS, MA, DSc, FHEA, FEBVS, FACPH, BM, BCh","doi":"10.1016/j.jvsv.2025.102399","DOIUrl":"10.1016/j.jvsv.2025.102399","url":null,"abstract":"","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"14 2","pages":"Article 102399"},"PeriodicalIF":2.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147394561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Concomitant Phlebectomy Extent on Outcomes in C2 Disease: A Propensity Score Matching Study","authors":"Kilsoo Yie MD, PhD,&nbsp;Arom Shin MD","doi":"10.1016/j.jvsv.2025.102397","DOIUrl":"10.1016/j.jvsv.2025.102397","url":null,"abstract":"","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"14 2","pages":"Article 102397"},"PeriodicalIF":2.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147394779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bioboosted Healing: Biologic and Allograft dressings in Venous Ulcer Care","authors":"Christina Guarin MSN","doi":"10.1016/j.jvsv.2025.102385","DOIUrl":"10.1016/j.jvsv.2025.102385","url":null,"abstract":"","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"14 2","pages":"Article 102385"},"PeriodicalIF":2.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147395059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}