{"title":"Disaster-associated venous thromboembolism countermeasures in Japan: Insights from past major earthquakes.","authors":"Keisuke Kamada, Eri Fukaya, Eriko Iwata, Daiki Uchida, Makoto Mo, Kazuhiko Hanzawa, Shinsaku Ueda, Nobuyoshi Azuma","doi":"10.1016/j.jvsv.2025.102312","DOIUrl":"10.1016/j.jvsv.2025.102312","url":null,"abstract":"<p><p>Japan experiences more than 1000 perceptible earthquakes annually, including major events such as the 2011 Great East Japan Earthquake and the 1995 Great Hanshin-Awaji Earthquake. These events lead to a documented increase in cardiovascular events, particularly venous thromboembolism (VTE), including pulmonary embolism and deep vein thrombosis (DVT). Disaster-associated VTE is influenced by Virchow's triad: hemodynamic stasis, hypercoagulability, and endothelial injury. The incidence of DVT after earthquakes ranges from 10% to 30%, often developing 1 to 2 weeks post disaster. Early interventions in evacuation shelters to prevent venous stasis and hypercoagulability are critical. Left untreated, DVT can progress to pulmonary embolism, which may be fatal; however, most cases are preventable through timely intervention and improved shelter environments. Various organizations, including the Disaster Medical Assistance Team, the Japan Medical Association Team, and local institutions, contribute to disaster medical responses. In 2016, the Disaster Countermeasure Committee was established by the Japanese Society of Phlebology to lead VTE prevention efforts, including DVT screening, compression stocking distribution, public awareness campaigns, and promoting cardboard beds to enhance shelter conditions. In preparation for future large-scale disasters, it is vital to share evidence-based knowledge with health care professionals and the public to decrease the burden of disaster-associated VTE.</p>","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":" ","pages":"102312"},"PeriodicalIF":2.8,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145040454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria Lourdes Del Río-Solá, Noelia Cenizo-Revuelta, Laura Saiz Viloria, Miguel Martin Pedrosa, Jose Antonio González-Fajardo
{"title":"The cardiovascular impact of chronic venous disease: A systematic review and meta-analysis.","authors":"Maria Lourdes Del Río-Solá, Noelia Cenizo-Revuelta, Laura Saiz Viloria, Miguel Martin Pedrosa, Jose Antonio González-Fajardo","doi":"10.1016/j.jvsv.2025.102310","DOIUrl":"10.1016/j.jvsv.2025.102310","url":null,"abstract":"<p><strong>Objective: </strong>To systematically evaluate the association between chronic venous disease (CVD) and cardiovascular (CV) risk, including major CV events and traditional risk factors, across diverse populations and study designs.</p><p><strong>Methods: </strong>A systematic review was conducted following PRISMA guidelines. PubMed, Scopus, and Web of Science were searched from January 2011 to March 2025 using Medical Subject Headings terms and free-text keywords. Inclusion criteria encompassed observational human studies evaluating the relationship between CVD and CV outcomes or risk factors. Data extraction was performed independently by two reviewers. Thematic analysis and coding of extracted data were supported using ATLAS.ti software. Twenty studies met the inclusion criteria, including cohort, cross-sectional, and case-control designs.</p><p><strong>Results: </strong>Seventeen of the 20 studies (85%) reported a significant association between CVD and at least one CV outcome, such as coronary artery disease, stroke, peripheral arterial disease, heart failure, or CV mortality. Odds and hazard ratios ranged from 1.3 to 3.8, with higher Clinical-Etiological-Anatomical-Physiological classes (C3-C6) consistently linked with greater CV risk. Eight studies identified greater higher prevalence of traditional risk factors-including hypertension, diabetes, obesity, and dyslipidemia-in patients with CVD. Two studies provided mechanistic insights, highlighting systemic inflammation and endothelial dysfunction as potential shared pathways. Population-based analyses with multivariable adjustments confirmed the independent nature of the association. A meta-analysis of six studies encompassing 393,875 individuals and 55,356 CV events was conducted. The pooled odds ratio for CV events in patients with CVD was 0.92 (95% confidence interval, 0.14-1.69), reaching statistical significance (P = .021). An adjusted expected odds ratio of 2.50 (95% confidence interval, 1.15-5.44) further reinforced the strength of the association. Heterogeneity was high (I<sup>2</sup> = 98%), but no publication bias was detected. Visual exploration through Galbraith, L'Abbé, and funnel plots supported the consistency of the findings.</p><p><strong>Conclusions: </strong>CVD is independently associated with increased CV morbidity and mortality, particularly in patients with moderate to severe disease. These findings suggest that CVD may serve as a clinical marker of systemic vascular dysfunction and support its inclusion in CV risk assessment frameworks. The quantitative synthesis confirms a significant association and highlights the importance of early CV screening in patients with CVD.</p>","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":" ","pages":"102310"},"PeriodicalIF":2.8,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145006314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammad A. Amarneh MD, Kyung Rae Kim MD, Mohammed H. Alomari MD, Ahmad I. Alomari MD
{"title":"Direct Percutaneous Abdominal Venous Access for Endovascular Therapy","authors":"Mohammad A. Amarneh MD, Kyung Rae Kim MD, Mohammed H. Alomari MD, Ahmad I. Alomari MD","doi":"10.1016/j.jvsv.2025.102309","DOIUrl":"10.1016/j.jvsv.2025.102309","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate the feasibility, safety, and clinical applications of ultrasound-guided direct percutaneous access to ectatic abdominal veins for the embolization of vascular malformations.</div></div><div><h3>Methods</h3><div>Medical records, imaging studies, and procedural details were retrospectively reviewed for patients who underwent embolization procedures for vascular malformations with ultrasound-guided percutaneous access to intra-abdominal veins, including the pelvic, retroperitoneal, and portomesenteric veins.</div></div><div><h3>Results</h3><div>A total of 38 direct percutaneous vein accesses were performed across 25 procedures in 9 patients (age range, 3-58 years). Access sites included retroperitoneal veins (n = 12), dilated and tortuous internal iliac vein branches (n = 8), the superior mesenteric vein (n = 8), the inferior mesenteric vein (n = 1), ileocolic vein (n = 8), and right colic vein (n = 1). Catheter sizes ranged from 3F to 5F. All procedures were technically successful. Seven minor access-related complications occurred; all were managed conservatively.</div></div><div><h3>Conclusions</h3><div>Ultrasound-guided percutaneous access to dilated intra-abdominal veins is feasible and associated with minimal morbidity. It offers a valuable alternative for patients with complex vascular malformations requiring access to deep abdominal veins.</div></div>","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"14 1","pages":"Article 102309"},"PeriodicalIF":2.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144992954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Misaki M. Kiguchi MD, MBA , Christian Anthony Campat DO , Deeptha Bejugam BS , Juan Carlos Jimenez MD , Ulka Sachdev MD , Niyati Bhatt MD , Alexander Rothstein BM, BA , Julie Bitner PA-C, BA , Leigh Ann O'Banion MD
{"title":"Ablation length, not modality type, determines healing outcomes in venous leg ulcers","authors":"Misaki M. Kiguchi MD, MBA , Christian Anthony Campat DO , Deeptha Bejugam BS , Juan Carlos Jimenez MD , Ulka Sachdev MD , Niyati Bhatt MD , Alexander Rothstein BM, BA , Julie Bitner PA-C, BA , Leigh Ann O'Banion MD","doi":"10.1016/j.jvsv.2025.102308","DOIUrl":"10.1016/j.jvsv.2025.102308","url":null,"abstract":"<div><h3>Objective</h3><div>Early endovenous intervention of the saphenous system improves healing and recurrence of venous leg ulcers (Clinical-Etiology-Anatomy-Pathophysiology class 6). As ablative methods continue to evolve, it is essential to identify outcome differences between the various techniques. This study aims to compare wound healing rates between primary nonthermal ablation (cyanoacrylate glue [CAG] or commercial polidocanol microfoam ablation [MFA]) and thermal ablation with adjunct MFA.</div></div><div><h3>Methods</h3><div>In this multicenter retrospective cohort study, patients with healed venous ulcers after nonthermal endovenous treatment were identified from four tertiary referral US institutions. Demographics, comorbidities, procedural, and wound data were collected. Patients whose full-length great saphenous vein was treated with a single nonthermal modality (CAG or MFA) were compared with those treated with radiofrequency ablation plus MFA of the below-knee segment. Multivariate linear regression was performed to identify predictors of wound healing.</div></div><div><h3>Results</h3><div>We identified 55 patients (27 primary CAG or MFA and 28 radiofrequency ablation plus MFA). The average age was 70 ± 12 years, 56% were male, and 53% had a body mass index of >30 kg/m<sup>2</sup>. Comorbidities were similar between the cohorts. The median ulcer size was 3 cm<sup>2</sup>. The median time to wound healing was 61 days (interquartile range, 30-258 days) with no significant difference between treatment modalities (<em>P</em> = .37), irrespective of ulcer size category. The rate of ulcer recurrence was 16% and did not differ between the cohorts (<em>P</em> = .46). Multivariate linear regression identified proximal access site as the only independent predictor of prolonged wound healing (<em>P</em> = .03).</div></div><div><h3>Conclusions</h3><div>Treatment of the full-length great saphenous vein with a single nonthermal modality (CAG or MFA) or a thermal modality plus MFA below the knee have comparable times to wound healing. This finding suggests that comprehensive treatment, irrespective of modality, of the entire great saphenous vein to the ankle is the preferred approach for optimal wound healing in Clinical-Etiology-Anatomy-Pathophysiology class 6 patients.</div></div>","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"14 1","pages":"Article 102308"},"PeriodicalIF":2.8,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144958999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Giant primary great saphenous vein aneurysm","authors":"Yan Yang MD , Juan Yang MD , Wen Hao Lu MD","doi":"10.1016/j.jvsv.2025.102307","DOIUrl":"10.1016/j.jvsv.2025.102307","url":null,"abstract":"","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"14 1","pages":"Article 102307"},"PeriodicalIF":2.8,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144959073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Exploring isolated inferior vena cava anomalies beyond the norm","authors":"Micaela R. Cuneo MD, Diane F. Hale MD","doi":"10.1016/j.jvsv.2025.102306","DOIUrl":"10.1016/j.jvsv.2025.102306","url":null,"abstract":"","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"14 1","pages":"Article 102306"},"PeriodicalIF":2.8,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144959075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kurt S. Schultz MD , Paula Pinto Rodriguez MD , Sahar Ali MD , Robert R. Attaran MD , Juan Carlos Perez Lozada MD , Steffen Huber MD , Britt Tonnessen MD , Edouard Aboian MD , Raul J. Guzman MD , Cassius Iyad Ochoa Chaar MD, MPH, MS
{"title":"Timing of outpatient stenting is associated with stent size in nonthrombotic iliac vein lesions","authors":"Kurt S. Schultz MD , Paula Pinto Rodriguez MD , Sahar Ali MD , Robert R. Attaran MD , Juan Carlos Perez Lozada MD , Steffen Huber MD , Britt Tonnessen MD , Edouard Aboian MD , Raul J. Guzman MD , Cassius Iyad Ochoa Chaar MD, MPH, MS","doi":"10.1016/j.jvsv.2025.102303","DOIUrl":"10.1016/j.jvsv.2025.102303","url":null,"abstract":"<div><h3>Objective</h3><div>Stent placement is commonly used to treat nonthrombotic iliac vein lesions (NIVLs). On the day of surgery, patients typically fast after midnight and may often present with volume deficits and various degrees of dehydration. This study aims to determine if the time of day stenting is performed predicts the size of the iliac vein stent used to treat NIVLs.</div></div><div><h3>Methods</h3><div>A retrospective study of patients who underwent outpatient stenting and first-time treatment for NIVLs at a single institution from January 2013 to March 2022 was performed. The exposure variable was the time of day the outpatient stenting was performed, serving as a proxy for fasting duration. Stent timing was dichotomized into an early cohort (procedures before 11 <span>am</span>) and a late cohort (procedures after 11 <span>am</span>). Small stent size was defined as 12 to 16 mm, and large stent size was defined as 18 to 22 mm. A multivariable logistic regression analysis evaluated the independent association between the timing of stenting and iliac vein stent size.</div></div><div><h3>Results</h3><div>Sixty-four patients met the inclusion criteria, with 53% (n = 34) in the late cohort. The median age of the study population was 53 years (interquartile range, 39-64 years). Patients were 75% female, 30% non-White, and 69% non-Hispanic. Although there were no significant differences in baseline characteristics or iliac vein measurements on intravascular ultrasound examination before stenting between the early and late cohorts, patients in the early cohort were significantly more likely to have a large stent size used compared with the late cohort (70% vs 44%; <em>P</em> = .037). On multivariable logistic regression, each additional hour later in the day that stenting was performed was associated with a 28% higher odds of using a smaller venous stent (<em>P</em> = .036). Older age also independently predicted the implantation of a smaller stent (odds ratio, 0.95; 95% confidence interval, 0.91-0.99; <em>P</em> = .022).</div></div><div><h3>Conclusions</h3><div>Outpatient stenting performed later in the day was associated with a smaller stent size in patients treated for NIVLs. A 9-hour delay in stent placement was associated with a 2-mm reduction in stent diameter (ie, one stent size smaller). Future studies should investigate the role of a preoperative hydration protocol in optimizing stent sizing for patients with iliac vein lesions.</div></div>","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"14 1","pages":"Article 102303"},"PeriodicalIF":2.8,"publicationDate":"2025-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144959017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Application of bacterial cellulose film as a wound dressing in varicose vein surgery: A randomized clinical trial","authors":"Allan Lemos Maia PhD , Esdras Marques Lins PhD , Fernanda Appolonio Rocha PhD , Layla Carvalho Mahnke PhD , Flávia Cristina Morone Pinto PhD , Tiago de Oliveira Pereira MD , Mariana Vieira Neves MD , Sarah Brandão Palácio PhD , Katharine Valéria Saraiva Hodel MSc , Josiane Dantas Viana Barbosa PhD , Simone Oliveira Penello PhD , Jaiurte Gomes Martins da Silva PhD , José Lamartine de Andrade Aguiar PhD","doi":"10.1016/j.jvsv.2025.102302","DOIUrl":"10.1016/j.jvsv.2025.102302","url":null,"abstract":"<div><h3>Background</h3><div>Chronic venous insufficiency is common all over the world. It is often related to lower limb varicose veins. Surgical treatment is necessary in most cases but the management of the operative wounds remains a challenge. Nowadays, there is no consensus on which is the ideal dressing for covering operative wounds, but features such as low cost, hypoallergenicity, and good adherence are expected. In this study, a material that meets all these features, the bacterial cellulose film (BCF), was evaluated in patients who underwent varicose vein surgery.</div></div><div><h3>Methods</h3><div>A randomized, prospective clinical trial was carried out at the Angiology and Vascular Surgery Department of the Hospital das Clínicas/EBSERH - UFPE, from May 2023 to September 2024. The study included 55 patients who underwent varicose vein surgery, divided in two groups: an experimental group, which used a BCF to cover microincisions, and a control group. which used microporous tape. Between postoperative days 4 and 6, patients were assessed for pain, itching, and wound appearance using the Southampton Wound Assessment Scale. The groups were homogeneous in all demographic data, presence of comorbidities, and Clinical-Etiology-Anatomy-Pathophysiology Clinical classification.</div></div><div><h3>Results</h3><div>Pain on removal was more common in the control group with a mean scale score of 3.46 ± 3.26 compared with 0.63 ± 1.38 (<em>P</em> < .001).</div></div><div><h3>Conclusions</h3><div>There was no statistical difference between the groups in itching and wound healing. BCF showed healing results comparable with microporous tape, with the advantage of generating less pain on removal.</div></div>","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"13 6","pages":"Article 102302"},"PeriodicalIF":2.8,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144959030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Precision therapy demands precision delivery in the evolution of treatment for low-flow vascular malformations","authors":"Naiem Nassiri MD, FSVS, RPVI","doi":"10.1016/j.jvsv.2025.102262","DOIUrl":"10.1016/j.jvsv.2025.102262","url":null,"abstract":"","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"13 5","pages":"Article 102262"},"PeriodicalIF":2.8,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144830404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Information for Readers","authors":"","doi":"10.1016/S2213-333X(25)00131-3","DOIUrl":"10.1016/S2213-333X(25)00131-3","url":null,"abstract":"","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"13 5","pages":"Article 102296"},"PeriodicalIF":2.8,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144830401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}