{"title":"Disaster-associated Venous Thromboembolism Countermeasures in Japan: Insights from Past Major Earthquakes.","authors":"Keisuke Kamada, Eri Fukaya, Eriko Iwata, Daiki Uchida, Makoto Mo, Kazuhiko Hanzawa, Shinsaku Ueda, Nobuyoshi Azuma","doi":"10.1016/j.jvsv.2025.102312","DOIUrl":"https://doi.org/10.1016/j.jvsv.2025.102312","url":null,"abstract":"<p><p>Japan experiences over 1,000 perceptible earthquakes annually, including major events such as the 2011 Great East Japan Earthquake and the 1995 Great Hanshin-Awaji Earthquake. These events lead to a documented increase in cardiovascular events, particularly venous thromboembolism (VTE), including pulmonary embolism (PE) and deep vein thrombosis (DVT). Disaster-associated VTE is influenced by Virchow's triad: hemodynamic stasis, hypercoagulability, and endothelial injury. The incidence of DVT following earthquakes ranges from 10-30%, often developing 1-2 weeks post-disaster. Early interventions in evacuation shelters to prevent venous stasis and hypercoagulability are critical. Left untreated, DVT can progress to PE, which may be fatal; however, most cases are preventable through timely intervention and improved shelter environments. Various organizations, including the Disaster Medical Assistance Team (DMAT), the Japan Medical Association Team (JMAT), and local institutions, contribute to disaster medical responses. In 2016, the Disaster Countermeasure Committee (DCC) was established by the Japanese Society of Phlebology to lead VTE prevention efforts, including DVT screening, compression stocking distribution, public awareness campaigns, and promoting cardboard beds to enhance shelter conditions. In preparation for future large-scale disasters, it is vital to share evidence-based knowledge with healthcare professionals and the public to reduce the burden of disaster-associated VTE.</p>","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":" ","pages":"102312"},"PeriodicalIF":2.8,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145040454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria Lourdes Del Río-Solá, Noelia Cenizo-Revuelta, Saiz Viloria Laura, Miguel Martin Pedrosa, Jose Antonio González-Fajardo
{"title":"THE CARDIOVASCULAR IMPACT OF CHRONIC VENOUS DISEASE: A SYSTEMATIC REVIEW AND META-ANALYSIS.","authors":"Maria Lourdes Del Río-Solá, Noelia Cenizo-Revuelta, Saiz Viloria Laura, Miguel Martin Pedrosa, Jose Antonio González-Fajardo","doi":"10.1016/j.jvsv.2025.102310","DOIUrl":"https://doi.org/10.1016/j.jvsv.2025.102310","url":null,"abstract":"<p><strong>Objective: </strong>To systematically evaluate the association between chronic venous disease (CVD) and cardiovascular (CV) risk, including major cardiovascular events and traditional risk factors, across diverse populations and study designs.</p><p><strong>Methods: </strong>A systematic review was conducted following PRISMA guidelines. PubMed, Scopus, and Web of Science were searched from January 2011 to March 2025 using MeSH terms and free-text keywords. Inclusion criteria encompassed observational human studies evaluating the relationship between CVD and CV outcomes or risk factors. Data extraction was performed independently by two reviewers. Thematic analysis and coding of extracted data were supported using ATLAS.ti software. Twenty studies met the inclusion criteria, including cohort, cross-sectional, and case-control designs.</p><p><strong>Results: </strong>Seventeen of the 20 studies (85%) reported a significant association between CVD and at least one cardiovascular outcome, such as coronary artery disease, stroke, peripheral arterial disease, heart failure, or cardiovascular mortality. Odds and hazard ratios ranged from 1.3 to 3.8, with higher CEAP classes (C3-C6) consistently linked to greater CV risk. Eight studies identified a higher prevalence of traditional risk factors-including hypertension, diabetes, obesity, and dyslipidemia-in patients with CVD. Two studies provided mechanistic insights, highlighting systemic inflammation and endothelial dysfunction as potential shared pathways. Population-based analyses with multivariable adjustments confirmed the independent nature of the association. A meta-analysis of six studies encompassing 393,875 individuals and 55,356 cardiovascular events was conducted. The pooled odds ratio for cardiovascular events in patients with CVD was 0.92 (95% CI: 0.14-1.69), reaching statistical significance (p = 0.021). An adjusted expected odds ratio of 2.50 (95% CI: 1.15-5.44) further reinforced the strength of the association. Heterogeneity was high (I<sup>2</sup> = 98%), but no publication bias was detected. Visual exploration through Galbraith, L'Abbé, and funnel plots supported the consistency of the findings.</p><p><strong>Conclusions: </strong>CVD is independently associated with increased cardiovascular morbidity and mortality, particularly in patients with moderate to severe disease. These findings suggest that CVD may serve as a clinical marker of systemic vascular dysfunction and support its inclusion in CV risk assessment frameworks. The quantitative synthesis confirms a significant association and highlights the importance of early cardiovascular screening in patients with CVD.</p>","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":" ","pages":"102310"},"PeriodicalIF":2.8,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145006314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammed A Amarneh, Kyung Rae Kim, Mohammed H Alomari, Ahmad I Alomari
{"title":"Direct access of intra-abdominal veins, feasibility, safety and clinical applications.","authors":"Mohammed A Amarneh, Kyung Rae Kim, Mohammed H Alomari, Ahmad I Alomari","doi":"10.1016/j.jvsv.2025.102309","DOIUrl":"https://doi.org/10.1016/j.jvsv.2025.102309","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the feasibility, safety, and clinical applications of ultrasound-guided direct percutaneous access to ectatic abdominal veins for the embolization of vascular malformations.</p><p><strong>Methods: </strong>The medical records, imaging studies, and procedural details were retrospectively reviewed for patients who underwent embolization procedures for vascular malformations with ultrasound-guided percutaneous access to intraabdominal veins, including pelvic, retroperitoneal, and portomesenteric veins.</p><p><strong>Results: </strong>A total of 38 direct percutaneous vein accesses were performed across 25 procedures in 9 patients (age range: 3-58 years). Access sites included retroperitoneal veins (n=12), dilated and tortuous internal iliac vein branches (n=8), the superior mesenteric vein (n=8), the inferior mesenteric vein (n=1), ileocolic vein (n=8), and right colic vein (n=1). Catheter sizes ranged from 3 to 5 French. All procedures were technically successful. Seven minor access-related complications occurred, all managed conservatively.</p><p><strong>Conclusion: </strong>Ultrasound-guided percutaneous access to dilated intraabdominal veins is feasible and associated with minimal morbidity. It offers a valuable alternative in patients with complex vascular malformations requiring access to deep abdominal veins.</p>","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":" ","pages":"102309"},"PeriodicalIF":2.8,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144992954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Misaki M Kiguchi, Christian Anthony Campat, Deeptha Bejugam, Juan Carlos Jimenez, Ulka Sachdev, Niyati Bhatt, Alexander Rothstein, Julie Bitner, Leigh Ann O'Banion
{"title":"Ablation Length, Not Modality Type, Determines Healing Outcomes in Venous Leg Ulcers.","authors":"Misaki M Kiguchi, Christian Anthony Campat, Deeptha Bejugam, Juan Carlos Jimenez, Ulka Sachdev, Niyati Bhatt, Alexander Rothstein, Julie Bitner, Leigh Ann O'Banion","doi":"10.1016/j.jvsv.2025.102308","DOIUrl":"https://doi.org/10.1016/j.jvsv.2025.102308","url":null,"abstract":"<p><strong>Objectives: </strong>Early endovenous intervention of the saphenous system improves healing and recurrence of venous leg ulcers (CEAP-6). As ablative methods continue to evolve, it is essential to identify outcome differences between the various techniques. This study aims to compare wound healing rates between primary non-thermal [cyanoacrylate glue (CAG) or commercial polidocanol microfoam ablation (MFA)] and thermal with adjunct MFA.</p><p><strong>Methods: </strong>In this multi-center retrospective cohort study, patients with healed venous ulcers after non-thermal endovenous treatment were identified from four tertiary referral US institutions. Demographics, co-morbidities, procedural, and wound data were collected. Patients whose full-length great saphenous vein (GSV) was treated with a single non-thermal modality (CAG or MFA) were compared to those treated with RFA + MFA of the below knee segment. Multivariate linear regression was performed to identify predictors of wound healing.</p><p><strong>Results: </strong>55 patients were identified (27 primary CAG or MFA and 28 RFA+MFA). The average age was 70±12, 56% were male, and 53% had BMI>30kg/m<sup>2</sup>. Co-morbidities were similar between the cohorts. Median ulcer size was 3cm<sup>2</sup>. Median time to wound healing was 61 days (IQR 30-258) with no significant difference between treatment modalities (p=0.37), irrespective of ulcer size category (Figure 1). Rate of ulcer recurrence was 16% and did not differ between the cohorts (p=0.46). Multivariate linear regression identified proximal access site as the only independent predictor of prolonged wound healing (p=0.03).</p><p><strong>Conclusions: </strong>Treatment of the full-length GSV with single non-thermal modality (CAG or MFA) or thermal plus MFA below the knee have comparable time to wound healing. This suggests comprehensive treatment, irrespective of modality, of the entire GSV to the ankle is the preferred approach for optimal wound healing in CEAP-6 patients.</p>","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":" ","pages":"102308"},"PeriodicalIF":2.8,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144958999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Exploring Isolated Inferior Vena Cava Anomalies Beyond the Norm.","authors":"Micaela R Cuneo, Diane F Hale","doi":"10.1016/j.jvsv.2025.102306","DOIUrl":"https://doi.org/10.1016/j.jvsv.2025.102306","url":null,"abstract":"","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":" ","pages":"102306"},"PeriodicalIF":2.8,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144959075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kurt S Schultz, Paula Pinto Rodriguez, Sahar Ali, Robert R Attaran, Juan Carlos Perez Lozada, Steffen Huber, Britt Tonnessen, Edouard Aboian, Raul J Guzman, Cassius Iyad Ochoa Chaar
{"title":"Timing of Outpatient Stenting Is Associated With Stent Size in Non-Thrombotic Iliac Vein Lesions.","authors":"Kurt S Schultz, Paula Pinto Rodriguez, Sahar Ali, Robert R Attaran, Juan Carlos Perez Lozada, Steffen Huber, Britt Tonnessen, Edouard Aboian, Raul J Guzman, Cassius Iyad Ochoa Chaar","doi":"10.1016/j.jvsv.2025.102303","DOIUrl":"https://doi.org/10.1016/j.jvsv.2025.102303","url":null,"abstract":"<p><strong>Objective: </strong>Stent placement is commonly used to treat non-thrombotic iliac vein lesions. On the day of surgery, patients typically fast after midnight and may often present with volume deficits and various degrees of dehydration. This study aims to determine if the time of day a venogram is performed predicts the size of the iliac vein stent used to treat non-thrombotic iliac vein lesions.</p><p><strong>Methods: </strong>A retrospective study of patients who underwent outpatient venograms and first-time treatment for non-thrombotic iliac vein lesions at a single institution from January 2013 to March 2022 was performed. The exposure variable was the time of day the outpatient venogram was performed, serving as a proxy for fasting duration. Venogram timing was dichotomized into an \"early cohort\" (procedures before 11 AM) and a \"late cohort\" (procedures after 11 AM). Small stent size was defined as 12-16 millimeters (mm), and large stent size was defined as 18-22 mm. A multivariable logistic regression analysis evaluated the independent association between the timing of venogram and iliac vein stent size.</p><p><strong>Results: </strong>Sixty-four patients met the inclusion criteria, with 53% (n=34) in the late cohort. The median age of the study population was 53 years (IQR, 39-64). Patients were 75% female, 30% non-White, and 69% non-Hispanic. Although there were no significant differences in baseline characteristics or iliac vein measurements on intravascular ultrasound before stenting between the early and late cohorts, patients in the early cohort were significantly more likely to have a large stent size used compared to the late cohort (70% vs. 44%, p=0.037). In multivariable logistic regression, each additional hour later in the day that a venogram was performed was associated with 28% higher odds of using a smaller venous stent (p = 0.036). Older age also independently predicted the implantation of a smaller stent (OR, 0.95; 95% CI, 0.91-0.99; p = 0.022).</p><p><strong>Conclusions: </strong>Outpatient venograms performed later in the day were associated with a smaller stent size in patients treated for non-thrombotic iliac vein lesions. A nine-hour difference in procedure timing was associated with a 2 mm decrease in stent size (i.e., one stent size smaller). Future studies should investigate the role of a preoperative hydration protocol in optimizing stent sizing for patients with iliac vein lesions.</p>","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":" ","pages":"102303"},"PeriodicalIF":2.8,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144959017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Allan Lemos Maia, Esdras Marques Lins, Fernanda Appolonio Rocha, Layla Carvalho Mahnke, Flávia Cristina Morone Pinto, Tiago de Oliveira Pereira, Mariana Vieira Neves, Sarah Brandão Palácio, Katharine Valéria Saraiva, Josiane Dantas Vieira Barbosa, Simone Oliveira Penello, Jaiurte Gomes Martins da Silva, José Lamartine de Andrade Aguiar
{"title":"Application of bacterial cellulose film as a wound dressing in varicose vein surgery: A randomized clinical trial.","authors":"Allan Lemos Maia, Esdras Marques Lins, Fernanda Appolonio Rocha, Layla Carvalho Mahnke, Flávia Cristina Morone Pinto, Tiago de Oliveira Pereira, Mariana Vieira Neves, Sarah Brandão Palácio, Katharine Valéria Saraiva, Josiane Dantas Vieira Barbosa, Simone Oliveira Penello, Jaiurte Gomes Martins da Silva, José Lamartine de Andrade Aguiar","doi":"10.1016/j.jvsv.2025.102302","DOIUrl":"10.1016/j.jvsv.2025.102302","url":null,"abstract":"<p><strong>Background: </strong>Chronic venous insufficiency is common all over the world. It is often related to lower limb varicose veins. Surgical treatment is necessary in most cases but the management of the operative wounds remains a challenge. Nowadays, there is no consensus on which is the ideal dressing for covering operative wounds, but features such as low cost, hypoallergenicity, and good adherence are expected.</p><p><strong>Objective: </strong>In this study, a material that meets all these features, the bacterial cellulose film (BCF), was evaluated in patients who underwent varicose vein surgery.</p><p><strong>Methods: </strong>A randomized, prospective clinical trial was carried out at the Angiology and Vascular Surgery Department of the Hospital das Clínicas/EBSERH - UFPE, from May 2023 to September 2024. The study included 55 patients who underwent varicose vein surgery, divided in two groups: an experimental group, which used a BCF to cover microincisions, and a control group. which used microporous tape. Between postoperative days 4 and 6, patients were assessed for pain, itching, and wound appearance using the Southampton Wound Assessment Scale. The groups were homogeneous in all demographic data, presence of comorbidities, and Clinical-Etiology-Anatomy-Pathophysiology Clinical classification.</p><p><strong>Results: </strong>Pain on removal was more common in the control group with a mean scale score of 3.46 ± 3.26 compared with 0.63 ± 1.38 (P < .001).</p><p><strong>Conclusions: </strong>There was no statistical difference between the groups in itching and wound healing. BCF showed healing results comparable with microporous tape, with the advantage of generating less pain on removal.</p>","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":" ","pages":"102302"},"PeriodicalIF":2.8,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144959030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Precision therapy demands precision delivery in the evolution of treatment for low-flow vascular malformations","authors":"Naiem Nassiri MD, FSVS, RPVI","doi":"10.1016/j.jvsv.2025.102262","DOIUrl":"10.1016/j.jvsv.2025.102262","url":null,"abstract":"","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"13 5","pages":"Article 102262"},"PeriodicalIF":2.8,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144830404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Information for Readers","authors":"","doi":"10.1016/S2213-333X(25)00131-3","DOIUrl":"10.1016/S2213-333X(25)00131-3","url":null,"abstract":"","PeriodicalId":17537,"journal":{"name":"Journal of vascular surgery. Venous and lymphatic disorders","volume":"13 5","pages":"Article 102296"},"PeriodicalIF":2.8,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144830401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}