Journal of Urology最新文献

{"title":"Impact of Discordance Between Magnetic Resonance Imaging and Ultrasound Volume Measurements on Prostate Fusion Biopsy Outcomes.","authors":"Bor-En Jong, Chen-Han Wilfred Wu, Pin-Hsuan Tsai, Yao-Chou Tsai","doi":"10.1097/JU.0000000000004544","DOIUrl":"https://doi.org/10.1097/JU.0000000000004544","url":null,"abstract":"","PeriodicalId":17471,"journal":{"name":"Journal of Urology","volume":" ","pages":"101097JU0000000000004544"},"PeriodicalIF":5.9,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143811601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial Comment.","authors":"Lexiaochuan Wen, Roger Li","doi":"10.1097/JU.0000000000004550","DOIUrl":"https://doi.org/10.1097/JU.0000000000004550","url":null,"abstract":"","PeriodicalId":17471,"journal":{"name":"Journal of Urology","volume":" ","pages":"101097JU0000000000004550"},"PeriodicalIF":5.9,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply by Authors.","authors":"Giancarlo Marra, Francesco Barletta, Simone Scuderi, Aberto Briganti, Paolo Gontero, Giorgio Gandaglia","doi":"10.1097/JU.0000000000004534","DOIUrl":"https://doi.org/10.1097/JU.0000000000004534","url":null,"abstract":"","PeriodicalId":17471,"journal":{"name":"Journal of Urology","volume":" ","pages":"101097JU0000000000004534"},"PeriodicalIF":5.9,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Urologic Oncology: Bladder, Penis, and Urethral Cancer and Basic Principles of Oncology.","authors":"Sam S Chang","doi":"10.1097/JU.0000000000004543","DOIUrl":"https://doi.org/10.1097/JU.0000000000004543","url":null,"abstract":"","PeriodicalId":17471,"journal":{"name":"Journal of Urology","volume":" ","pages":"101097JU0000000000004543"},"PeriodicalIF":5.9,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Chlorthalidone and Hydrochlorothiazide on Twelve-Hour versus Twenty-Four Hour Urinary Calcium Excretion.","authors":"Daniel A Wollin, Hassan Fattah, John R Asplin, David S Goldfarb","doi":"10.1097/JU.0000000000004562","DOIUrl":"https://doi.org/10.1097/JU.0000000000004562","url":null,"abstract":"<p><strong>Purpose: </strong>Urine calcium excretion is greater after dinner and urine volumes are lower. The result is higher urine calcium concentrations, which may confer greater risk of stone formation, at night. We considered whether night-time administration - as compared with daytime administration - of thiazides would be more effective for stone prevention.</p><p><strong>Materials and methods: </strong>We performed 12-hour urine collections in 7 patients taking 25 mg of chlorthalidone (CTD) and 10 patients taking 25 mg of hydrochlorothiazide (HCTZ). Participants completed urine collections at baseline, again after a week of morning medication administration, and again after a week of evening administration, all on repeated self-selected diets.</p><p><strong>Results: </strong>Chlorthalidone reduced urine calcium excretion for both 12-hour periods whether administered in the morning or in the evening: morning dosing lowered urine calcium from 130±70 mg/gram Cr at baseline, to 76±52 mg/gram Cr (P<0.02); evening dosing lowered it to 87±51 mg/gram Cr, which was not significant. On the other hand, HCTZ did not reduce urine calcium excretion regardless of the time of administration: mean 24-hour urine calcium excretion (UCa) was 124±38 mg/gram Cr at baseline and 106±40 mg/gram Cr when HCTZ was given in AM, and 117±54 mg/gram Cr when given in PM.</p><p><strong>Conclusion: </strong>We conclude that the long-acting and more effective CTD is a preferable agent for stone prevention. Time of administration does not appear to be important, although morning administration may more effectively address higher post-dinner calcium excretion. The most commonly used thiazide (HCTZ) is shorter acting, frequently dosed once per day, but does not appear to reduce urine calcium excretion at this dose.</p>","PeriodicalId":17471,"journal":{"name":"Journal of Urology","volume":" ","pages":"101097JU0000000000004562"},"PeriodicalIF":5.9,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial Comment.","authors":"Andrew Rosenzweig, Charles Welliver","doi":"10.1097/JU.0000000000004536","DOIUrl":"10.1097/JU.0000000000004536","url":null,"abstract":"","PeriodicalId":17471,"journal":{"name":"Journal of Urology","volume":" ","pages":"101097JU0000000000004536"},"PeriodicalIF":5.9,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143780388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utility of Preoperative Antimicrobial Prophylaxis in Hypospadias Repair: Results From NSQIP-Pediatrics.","authors":"Michael F Basin, Maithili Gopalakrishnan, Nicole Ackerman, Matthew D Mason, Anthony J Tracey, Ahmed Souid, Jeffrey A Villanueva","doi":"10.1097/JU.0000000000004558","DOIUrl":"https://doi.org/10.1097/JU.0000000000004558","url":null,"abstract":"<p><strong>Introduction: </strong>Literature supporting antimicrobial prophylaxis for hypospadias repairs is lacking, with largest studies including several hundred subjects. We sought to evaluate the association of a single dose of preoperative antibiotics in hypospadias repairs on postoperative outcomes using National Surgical Quality Improvement Program Pediatrics (NSQIP-P).</p><p><strong>Methods: </strong>The 2021-2022 NSQIP-P database was used to categorize hypospadias repairs into 3 groups - (1) 1-stage distal hypospadias repairs, (2) 1-stage proximal hypospadias repairs and second/third stage urethroplasties, and (3) repair of hypospadias complications. Patients with missing data regarding preoperative antibiotic prophylaxis administration were excluded. We evaluated the risk of wound complications (wound infection or dehiscence) and urinary tract infections (UTI). Binomial logistic regressions were performed with selected covariates including age, race, prematurity, relative value unit, operative time, American Society of Anesthesiologists score, and antibiotic prophylaxis.</p><p><strong>Results: </strong>There were 5026 patients in group 1, 1428 patients in group 2, and 1159 patients in group 3. 6392 (84.0%) patients received preoperative antibiotics. Overall, UTI and wound complications rate was about 3%. On multivariable analysis, preoperative antibiotics were associated with decreased wound complications in longer procedures (p=0.018).</p><p><strong>Conclusion: </strong>Preoperative antibiotics correlated with decreased wound complications in longer procedures. Due to the overall very low incidence of postoperative complications, clinicians should consider omitting preoperative antibiotics in hypospadias repairs, particularly in lower risk patients.</p>","PeriodicalId":17471,"journal":{"name":"Journal of Urology","volume":" ","pages":"101097JU0000000000004558"},"PeriodicalIF":5.9,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143772647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perioperative Complications and Omission of Ureteral Stents During Robot-Assisted Radical Cystectomy With Intracorporeal Ileal Conduit.","authors":"Jacob E Tallman, Emily A Vertosick, Syed M Alam, Fady J Baky, S Machele Donat, Eugene J Pietzak, Eugene K Cha, Timothy F Donahue, Bernard H Bochner, Andrew J Vickers, Alvin C Goh","doi":"10.1097/JU.0000000000004387","DOIUrl":"10.1097/JU.0000000000004387","url":null,"abstract":"<p><strong>Purpose: </strong>Ureteral stents are commonly placed intraoperatively during radical cystectomy, although their efficacy in reducing complications is unproven. We compared clinical outcomes among patients undergoing robot-assisted radical cystectomy with intracorporeal ileal conduit (RARC-IC) with or without ureteral stents to determine if omission of ureteral stents affects postoperative complications.</p><p><strong>Materials and methods: </strong>All RARC-IC surgeries performed at our institution between November 2017 and June 2023 were reviewed. Beginning August 2021, ureteral stents were routinely omitted. Primary outcome was ureteroenteric anastomosis complications (urine leak, UTI, abscess, and/or sepsis) within 30 and 90 days of RARC-IC. Secondary outcomes included rates of wound infections, urgent care center visits, inpatient readmissions, and ureteral stricture.</p><p><strong>Results: </strong>Among 133 patients included, 90 patients (68%) received a ureteral stent and 43 (32%) did not. Composite ureteroenteric anastomosis complications were higher in the stented group (20% vs 9.5%, 10% difference, 95% CI, -3.4% to 24%, <i>P</i> = .2), though not statistically significant. The stented group had a significantly higher 30-day UTI rate (19% difference, 95% CI, 9.0%-29%, <i>P</i> = .007). The 30-day readmission rates were higher in the stented group, although differences did not meet statistical significance (19% vs 9.8%, 9.1% difference, 95% CI, -4.8% to 23%, <i>P</i> = .3). Limitations include lack of randomization and inability to evaluate some outcomes, including ureteral obstruction or strictures.</p><p><strong>Conclusions: </strong>Omission of ureteral stent placement at RARC-IC is safe and feasible. Randomized trials are warranted to determine the effects of stents on risk of postoperative complications after RARC-IC.</p>","PeriodicalId":17471,"journal":{"name":"Journal of Urology","volume":" ","pages":"437-446"},"PeriodicalIF":5.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11888893/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142818529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of Prognostic Models for Renal Cell Carcinoma Recurrence, Cancer-Specific Mortality, and All-Cause Mortality.","authors":"Anita Robert, Ranjeeta Mallick, Daniel I McIsaac, Luke T Lavallée, Bimal Bhindi, Daniel Heng, Lori A Wood, Ricardo Rendon, Simon Tanguay, Anthony Finelli, Rahul K Bansal, Aly-Khan Lalani, Naveen Basappa, Miles P Mannas, Jasmir G Nayak, Georg A Bjarnason, Jean-Baptiste Lattouf, Frédéric Pouliot, Patrick O Richard, Camilla Tajzler, Rodney H Breau","doi":"10.1097/JU.0000000000004348","DOIUrl":"10.1097/JU.0000000000004348","url":null,"abstract":"<p><strong>Purpose: </strong>Postoperative prognostic tools allow for improved prediction of future recurrence risk, patient counseling, assessment of eligibility for adjuvant treatments, and appropriate follow-up surveillance. The purpose of this analysis was to validate prognostic models for patients with kidney cancer.</p><p><strong>Materials and methods: </strong>The Canadian Kidney Cancer information system is a prospective cohort of patients managed at 14 institutions since January 1, 2011, to present. The Canadian Kidney Cancer information system was used to assess 15 predictive models for kidney cancer recurrence, 6 for cancer-specific mortality, and 4 for all-cause mortality in patients with a solitary, nonmetastatic kidney tumor treated with surgery (partial or radical nephrectomy). Discrimination was measured using C statistics, 5-year calibration plots for calibration, and decision curve analysis at 5 years after surgery for net benefit when considering adjuvant therapy.</p><p><strong>Results: </strong>Seven thousand one hundred seventy-four patients were included. For kidney cancer recurrence, C statistics ranged from 0.62 to 0.83, depending on whether the model was derived and applied to all patients without further stratification, specific risk groups, or specific histologic subtypes. Cancer-specific mortality models had C statistics ranging from 0.60 to 0.89 and all-cause mortality models from 0.60 to 0.73. Using decision curve analysis in patients with clear-cell renal cell carcinoma, the best models for choosing adjuvant therapy to prevent recurrence and cancer-related death were the Mayo Clinic prediction models.</p><p><strong>Conclusions: </strong>Model performance varied considerably with some suitable for clinical use. If using prediction models to select adjuvant therapy, the Mayo Clinic models were best when applied to a large contemporary cohort of Canadian patients.</p>","PeriodicalId":17471,"journal":{"name":"Journal of Urology","volume":" ","pages":"455-466"},"PeriodicalIF":5.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142770220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial Comment.","authors":"Eugenia Vercelli, Carl Van Haute, Thomas Tailly","doi":"10.1097/JU.0000000000004398","DOIUrl":"10.1097/JU.0000000000004398","url":null,"abstract":"","PeriodicalId":17471,"journal":{"name":"Journal of Urology","volume":" ","pages":"483"},"PeriodicalIF":5.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143007337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}