Journal of Urology最新文献

{"title":"<i>The Journal of Urology</i>^® Home Study Course 2025 Volume 213/214.","authors":"","doi":"10.1097/JU.0000000000004458","DOIUrl":"https://doi.org/10.1097/JU.0000000000004458","url":null,"abstract":"","PeriodicalId":17471,"journal":{"name":"Journal of Urology","volume":"213 4","pages":"542-543"},"PeriodicalIF":5.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143573129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of Prediction Models for Severe Pain and Urinary Symptoms After Ureteroscopy With Ureteral Stent Placement: Results From the STENTS Study and Initial Validation of Pain Interference.","authors":"Gregory E Tasian, Jonathan D Harper, Hussein R Al-Khalidi, Hongqiu Yang, Naim M Maalouf, Michele Curatolo, H Henry Lai, Alana Desai, Jodi A Antonelli, Jing Huang, Justin B Ziemba, Hunter Wessells, Ziya Kirkali, Charles D Scales, Peter P Reese","doi":"10.1097/JU.0000000000004370","DOIUrl":"10.1097/JU.0000000000004370","url":null,"abstract":"<p><strong>Purpose: </strong>We developed prediction models for severe pain and urinary symptoms after ureteroscopy with ureteral stent placement.</p><p><strong>Materials and methods: </strong>The development cohort included 424 adults and adolescents enrolled in the multicenter STENTS prospective cohort study who underwent ureteroscopy with stent placement for urinary stones. The validation cohort was an independent prospective cohort of 115 adults. The outcomes were severe pain intensity and pain interference, measured by the Patient-Reported Outcomes Measurement Information System, and severe urinary symptoms, measured by the Ureteral Stent Symptom Questionnaire. The top quartile of symptoms on postoperative days 1 and 3 was defined as severe. Generalized estimating equation models were used to predict severe symptoms on postoperative days 1, 3, 5, and 7 to 9 in the development cohort and severe pain interference on days 1 and 7 in the validation cohort.</p><p><strong>Results: </strong>Female sex, younger age, higher BMI, baseline pain interference, number of chronic pain conditions, renal stone location, and history of anxiety predicted severe pain. In the development cohort, the C statistics were 0.83 (95% CI 0.80-0.85) for severe pain interference and 0.82 (95% CI 0.79-0.84) for severe pain intensity. A model in which baseline urinary symptoms replaced pain interference had excellent discrimination for severe urinary symptoms (C statistic 0.83; 95% CI 0.81-0.85). In the validation cohort, the C statistic was 0.7 for severe pain interference (95% CI 0.54-0.78).</p><p><strong>Conclusions: </strong>Preoperative characteristics accurately predicted severe pain and urinary symptoms after ureteroscopy with stent placement. On further validation, these models could guide clinical decisions to improve surgical outcomes.</p>","PeriodicalId":17471,"journal":{"name":"Journal of Urology","volume":" ","pages":"475-484"},"PeriodicalIF":5.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11888894/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142801371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spontaneous Resolution of Primary Obstructive Megaureter: Risk Stratification and Prediction Based on Early Sonographic Factors.","authors":"Adree Khondker, Jin Kyu Kim, Ihtisham Ahmad, Jethro C C Kwong, Kay Rivera, Camilla B Moreno, Michael E Chua, Mandy Rickard, Armando J Lorenzo","doi":"10.1097/JU.0000000000004355","DOIUrl":"10.1097/JU.0000000000004355","url":null,"abstract":"<p><strong>Purpose: </strong>We describe and develop predictors for spontaneous resolution of primary obstructive megaureter (POM) from early ultrasound (US) measures.</p><p><strong>Materials and methods: </strong>Children referred to our institution between 2007 and 2023 for POM were reviewed. POM was defined as hydroureteronephrosis with ureteral dilation > 7 mm. We excluded patients with other etiologies for upper tract dilation. Resolution was defined as decrease in hydronephrosis to < 10 mm anteroposterior diameter (APD) or Society for Fetal Urology grade ≤ 2 or ≤ 7 mm in hydroureter. Patients were censored if they underwent surgical intervention or were lost to follow-up before documenting resolution. Kaplan-Meier curves were drawn to illustrate the cumulative resolution rate and determine univariate associations. Cox proportional hazards regression was performed to identify significant predictors for early resolution, and C index was calculated.</p><p><strong>Results: </strong>A total of 159 patients were included, with a median index age of 2 months and a median follow-up of 30 months. Of these, 89 patients reached spontaneous resolution during monitoring, and likelihood of surgical indication at 1 year from US was 30%. APD > 15 mm, high-grade hydronephrosis, ureteral dilation > 10 mm, and ureter tortuosity at presentation were associated with a lower likelihood of resolution for individual Kaplan-Meier curves. A Cox regression model trained on these predictors achieved an adjusted C index of 0.68, and low APD remained associated with a higher likelihood of resolution.</p><p><strong>Conclusions: </strong>Early sonographic features in POM, specifically APD, are associated with the likelihood of spontaneous resolution. Patients with high-risk features at first US warrant closer follow-up.</p>","PeriodicalId":17471,"journal":{"name":"Journal of Urology","volume":" ","pages":"485-493"},"PeriodicalIF":5.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142770218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial Comment.","authors":"Nicholas H Chakiryan","doi":"10.1097/JU.0000000000004353","DOIUrl":"10.1097/JU.0000000000004353","url":null,"abstract":"","PeriodicalId":17471,"journal":{"name":"Journal of Urology","volume":" ","pages":"465"},"PeriodicalIF":5.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142801398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Multi-Institutional Study of Magnetic Resonance/Ultrasound Fusion-Guided Nanoparticle-Directed Focal Therapy for Prostate Ablation: Erratum.","authors":"Steven E Canfield, Arvin K George, Joshua S Jue, Sara C Lewis, Matthew S Davenport, Varaha S Tammisetti, Mahir Maruf, Leonardo D Borregalaes, Yara Kadria-Vili, Jon A Schwartz, Jennifer West, Naomi J Halas, Ardeshir R Rastinehad","doi":"10.1097/JU.0000000000004384","DOIUrl":"https://doi.org/10.1097/JU.0000000000004384","url":null,"abstract":"","PeriodicalId":17471,"journal":{"name":"Journal of Urology","volume":"213 4","pages":"541"},"PeriodicalIF":5.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143573134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"HF01-01 The \"Exhibition of Living Patients\"-Hutchinson, Ethics and Urology: Erratum.","authors":"Shelby P Smith, Michael E Moran","doi":"10.1097/JU.0000000000004388","DOIUrl":"https://doi.org/10.1097/JU.0000000000004388","url":null,"abstract":"","PeriodicalId":17471,"journal":{"name":"Journal of Urology","volume":"213 4","pages":"541"},"PeriodicalIF":5.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143573135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply by Authors.","authors":"Bradley A Erickson, Mei N Tuong, Alithea N Zorn, Charles H Schlaepfer, Nejd F Alsikafi, Benjamin N Breyer, Joshua A Broghammer, Jill C Buckley, Sean P Elliott, Jeremy B Myers, Andrew C Peterson, Keith F Rourke, Thomas G Smith, Alex J Vanni, Bryan B Voelzke, Lee C Zhao","doi":"10.1097/JU.0000000000004410","DOIUrl":"https://doi.org/10.1097/JU.0000000000004410","url":null,"abstract":"","PeriodicalId":17471,"journal":{"name":"Journal of Urology","volume":"213 4","pages":"522-523"},"PeriodicalIF":5.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143573201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Male Infertility.","authors":"Craig Niederberger","doi":"10.1097/JU.0000000000004363","DOIUrl":"10.1097/JU.0000000000004363","url":null,"abstract":"","PeriodicalId":17471,"journal":{"name":"Journal of Urology","volume":" ","pages":"529-530"},"PeriodicalIF":5.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142864754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial Comment.","authors":"Katelyn Spencer, Amanda F Buchanan","doi":"10.1097/JU.0000000000004442","DOIUrl":"10.1097/JU.0000000000004442","url":null,"abstract":"","PeriodicalId":17471,"journal":{"name":"Journal of Urology","volume":" ","pages":"502-503"},"PeriodicalIF":5.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143080560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Discordance Between Magnetic Resonance Imaging and Ultrasound Volume Measurements on Prostate Fusion Biopsy Outcomes.","authors":"Tabea Borde, Nicole A Varble, Lindsey A Hazen, Laetitia Saccenti, Charisse Garcia, Meredith Digennaro, Sandeep Gurram, Peter A Pinto, Baris Turkbey, Bradford J Wood","doi":"10.1097/JU.0000000000004368","DOIUrl":"10.1097/JU.0000000000004368","url":null,"abstract":"<p><strong>Purpose: </strong>Our goal was to determine whether the difference between MRI-based and ultrasound (US)-based volume measurements are associated with MRI/US-targeted fusion-guided biopsy outcomes.</p><p><strong>Materials and methods: </strong>This retrospective, single-center study involved 4177 consecutive patients biopsied between 2010 and 2023 using both MRI/US-targeted fusion and systematic biopsy. Biopsies were indicated because of elevated PSA levels or abnormal multiparametric MRI results. US volume measurements were calculated using the triplane ellipsoid formula, and MRI volumes were obtained by semiautomatic planimetric segmentation. Performance of fusion biopsy compared with systematic biopsy was analyzed with respect to the discordance between MRI and US volume measurements.</p><p><strong>Results: </strong>In 2736 patients (66%), biopsy detected prostate cancer. In cases where both techniques yielded prostate cancers (1695/2736 [62%]), a statistically higher proportion of patients had higher Gleason scores on MRI/US-targeted fusion biopsy compared with systematic biopsy (343 patients [20.2%] vs 137 patients [8.1%], <i>P</i> < .001). MRI volume measurements were significantly smaller compared with US volume measurements (median [IQR] 54 mL [39-77], 56 mL [40-80], respectively, <i>P</i> < .001). Beyond 5 mL volume discordance, MRI/US-targeted fusion biopsy gradually showed less added diagnostic benefit compared with systematic biopsy. In the ≤ 5 mL cohort, MRI/US-targeted fusion biopsy detected more aggressive tumors in 4 times as many patients as systematic biopsy (136 vs 32 patients, <i>P</i> < .001).</p><p><strong>Conclusions: </strong>Although MRI/US-targeted fusion biopsy detected more prostate cancers than systematic biopsy, the performance of MRI/US-targeted fusion biopsy declined with more discordance between volumes measured in MRI vs US. Awareness of volume discordance in MRI- and US-based volume measurements should alert the operator about the possibility of reduced performance of MRI/US-targeted fusion biopsy.</p><p><strong>Clinical trial registration no.: </strong>NCT00102544.</p>","PeriodicalId":17471,"journal":{"name":"Journal of Urology","volume":" ","pages":"428-436"},"PeriodicalIF":5.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11888895/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142807539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}