Journal of thermal biology最新文献

{"title":"EDITORIAL: Thermoregulatory and metabolic adaptations in a changing world.","authors":"Julia Nowack, Katie Marshall, Jérémy Terrien, Sylvain Giroud","doi":"10.1016/j.jtherbio.2025.104062","DOIUrl":"https://doi.org/10.1016/j.jtherbio.2025.104062","url":null,"abstract":"","PeriodicalId":17428,"journal":{"name":"Journal of thermal biology","volume":" ","pages":"104062"},"PeriodicalIF":2.9,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143189214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Temperature-dependent sleep patterns in Drosophila","authors":"Sanjay Ramnarayan Yadav ,&nbsp;Martina Gáliková ,&nbsp;Peter Klepsatel","doi":"10.1016/j.jtherbio.2024.104026","DOIUrl":"10.1016/j.jtherbio.2024.104026","url":null,"abstract":"<div><div>Sleep is a fundamental physiological process conserved through evolution, from worms to humans. Understanding how temperature influences sleep is essential for comprehending the complexities of animal behavior, physiology, and their adaptations to thermal environments. This study explores the impact of temperature on sleep behavior and patterns in <em>Drosophila melanogaster</em>. Through a comprehensive analysis, we assessed how temperatures during development and adulthood affect sleep duration and fragmentation. Our results show that exposure to non-optimal temperatures increases overall sleep duration, primarily by extending daytime sleep. Sleep patterns were also substantially modulated by developmental temperature. Flies that developed at 29 °C exhibited longer sleep durations compared to those that developed at either 19 °C or 25 °C. In general, sleep was more prevalent than wakefulness under most conditions, particularly at non-optimal temperatures. At intermediate temperatures, sleep became more fragmented and episodes shorter. The interplay between sleep and wakefulness varied depending on both population and developmental temperature. Developmental and adult temperatures also influenced sleep latency, the time it takes to fall asleep. Interestingly, the impact of temperature on daytime sleep latency differed among populations, whereas nighttime sleep latency consistently increased with temperature for all groups. Flies that developed at 29 °C showed shorter sleep latencies than those from other temperatures, both during the day and night. Finally, a strong negative correlation was observed between total sleep duration and daily locomotor activity across all groups and temperatures. These findings underscore the critical role of environmental temperature in regulating sleep behavior in <em>Drosophila</em>, with potential implications for understanding temperature-dependent sleep mechanisms in other organisms.</div></div>","PeriodicalId":17428,"journal":{"name":"Journal of thermal biology","volume":"127 ","pages":"Article 104026"},"PeriodicalIF":2.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142864751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New insights into the neurophysiological effects of heat stress on the Chinese mitten crab (Eriocheir sinensis)","authors":"Cong Zhang ,&nbsp;Dunqian Deng ,&nbsp;Yi Wu ,&nbsp;Lexue Song ,&nbsp;Jiayin Geng ,&nbsp;Huixia Feng ,&nbsp;Su Jiang ,&nbsp;Kai Zhang ,&nbsp;Yongxu Cheng ,&nbsp;Shaowu Yin","doi":"10.1016/j.jtherbio.2025.104055","DOIUrl":"10.1016/j.jtherbio.2025.104055","url":null,"abstract":"<div><div>Climate warming and frequent incidents of extreme high temperatures are serious global concerns. Heat stress induced by high temperature has many adverse effects on animal physiology, especially in aquatic poikilotherms. Chinese mitten crab (<em>Eriocheir sinensis</em>) is sensitive to high temperatures, this study evaluated the harmful effects of heat stress on the neurotoxicity, intestinal health, microbial diversity, and metabolite profiles. The results showed that heat stress caused histopathological damages and altered the ultrastructure of lesions in the cranial ganglia. Heat stress significantly upregulated the mRNA expression of apoptosis-related genes, and significantly altered the expression of neurotransmitter receptors. In addition, heat stress induced significant intestinal damages that mainly manifested as a significant increase in the activity of diamine oxidase in the serum and contents of histamine in the intestine. The diversity and abundance of intestinal microbiota altered abnormally in <em>E</em>. <em>sinensis</em> exposed to heat stress, and the bacteria that exhibited significant variations in abundance were closely related to the production of neurotransmitters and neuromodulators. Heat stress caused significant changes in the intestinal metabolite profiles, which mainly involved the amino acid and lipid metabolism pathways. Analysis of the correlation showed that the abnormal changes in metabolites were closely related to differences in the abundance of intestinal microbiota. Therefore, this study showed that heat stress could cause neurophysiological toxic effects, which may be related to intestinal ecological imbalance.</div></div>","PeriodicalId":17428,"journal":{"name":"Journal of thermal biology","volume":"127 ","pages":"Article 104055"},"PeriodicalIF":2.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143007240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":">6°(C) of separation: Exploring the difference between perceived and measured temperature","authors":"Jennifer M. Fitchett","doi":"10.1016/j.jtherbio.2025.104044","DOIUrl":"10.1016/j.jtherbio.2025.104044","url":null,"abstract":"<div><div>Questionnaires exploring tourists' perceptions of ideal climatic conditions are argued to be a more suitable data source for the development of tourism climate indices than the utilization and integration of expert opinion and pre-established thresholds. This assumes that those tourist respondents can accurately quantify meteorological conditions at a given point in time, and effectively discriminate between meteorological thresholds of suitable and unsuitable conditions. For variables such as rainfall and sunshine hours, this assumption is fairly reasonable. However, where tourists’ perceptions, captured through questionnaire responses, are used to set thresholds for air temperature and thermal comfort, it is important to determine whether those perceptions are valid. Previous studies contest this, indicating considerable differences in perceptions of heat thresholds based on terminology, nationality, destination, and time of the year. In this study, a benchmarking exercise is performed comparing perceived temperatures and thermal comfort to measured values, through questionnaires administered to 984 adults in South Africa. Findings indicated that while 19.9% of responses are within 1 °C of measured temperatures, up to 12.8% of respondents perceive temperatures as being at least 6 °C higher or lower than the measured values. There are no clear geographic or demographic variables that effectively discriminate between accurate and inaccurate responses. When asked to classify their level of thermal comfort, as opposed to quantifying temperatures, results aligned more closely with measures and classifications of effective temperature. Based on these results, we argue that greater caution should be applied when using temperature thresholds derived from questionnaire data in developing and calibrating any biometeorological indices, and focus instead should be placed on catergorized levels of self-reported thermal comfort in environments where raw meteorological conditions are measured.</div></div>","PeriodicalId":17428,"journal":{"name":"Journal of thermal biology","volume":"127 ","pages":"Article 104044"},"PeriodicalIF":2.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143007606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acclimation, thermal tolerance and aerobic metabolism of narrow-clawed crayfish, Pontastacus leptodactylus (Eschscholtz, 1823)","authors":"Mehmet Kır,&nbsp;İbrahim Ege Çınar,&nbsp;Murat Can Sunar,&nbsp;Mustafa Topuz","doi":"10.1016/j.jtherbio.2025.104045","DOIUrl":"10.1016/j.jtherbio.2025.104045","url":null,"abstract":"<div><div>Ectotherms are considered more susceptible to global warming. Variations in ambient temperature are especially alarming as the majority of animals are ectothermic, with temperature seen as a crucial determinant of their ecology, biogeography, behaviour, and physiology. Ectotherms, which depend on external ambient temperatures to regulate their body temperature, exhibit various physiological and metabolic responses to variations in temperature. These responses are essential for comprehending how these species will acclimatise to changing water temperatures and the consequent alterations in oxygen availability. This study assessed the acclimation ability, temperature tolerance, and metabolic rate of narrow-clawed crayfish (<em>Pontastacus leptodactylus</em>) to elucidate the crayfish's responses to potential climate change. Our study showed that the narrowed clawed crayfish is a species that exhibits high thermal tolerance, with an extensive dynamic (1114 °C²), static thermal polygon area (966 °C²), resistance zone of 103 °C² and the ability to withstand extreme temperatures (CT_min-CT_max: 1.60–36.8 °C). The acclimation temperature has minimal impact on the thermal tolerance of the crayfish (<em>P</em> &lt; 0.01). The optimal temperature range for SMR of <em>Pontastacus leptodactylus</em> is 20–25 °C, within which a decline in standard metabolic rate (SMR) occurs as temperature rises.</div></div>","PeriodicalId":17428,"journal":{"name":"Journal of thermal biology","volume":"127 ","pages":"Article 104045"},"PeriodicalIF":2.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143007608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative analysis of the silver-gold and copper-titanium dioxide hybrid nanoparticles impact on flow and heat transfer of the pulsatile blood in occluded cerebral artery","authors":"Nahid Najafi ,&nbsp;Wala Almosawy ,&nbsp;Marwan S. Abbas ,&nbsp;Arash Goligerdian ,&nbsp;Mohammad Najafi ,&nbsp;Negar Abdi ,&nbsp;Aram Ardalan ,&nbsp;Saman Aminian","doi":"10.1016/j.jtherbio.2025.104060","DOIUrl":"10.1016/j.jtherbio.2025.104060","url":null,"abstract":"<div><div>Arterial stenosis, which is the progressive narrowing of the lumen of blood vessels, severely compromises perfusion and leads to complex hemodynamic alterations. Evolving to address this challenge, hybrid nanofluids have emerged as a truly transformative solution due to their superior thermal and fluid properties. The present study numerically investigates the flow and heat transfer phenomena of two hybrid nanofluids, namely Silver-Gold (Ag-Au) and Copper-Titanium dioxide (Cu-TiO₂), in a bifurcated artery with 50% stenosis. A three-dimensional computational model based on the FEM was developed to simulate the pulsatile, Newtonian, and incompressible blood flow. The effects of nanoparticle volume fraction, pulsation rate, and the stenosis geometry were systematically investigated on temperature distribution, velocity profiles, wall shear stress, and heat flux. It was observed that increasing the volume fraction of nanoparticles heightens thermal conductivity and, thus, heat transfer efficiency. For instance, at a volume fraction of 0.1, the hybrid Silver-Gold nanofluid achieved the highest ANN of 24.188 in comparison with the Cu- TiO₂ at 20.456. The interaction of pulsatile flow with nanoparticles further augmented heat flux via periodic thinning of the thermal boundary layer, hence fostering flatter temperature profiles. Even though both hybrid nanofluids had comparable wall shear stress values of ∼1.426 N/cm², Silver-Gold nanoparticles manifested better thermal efficiency and uniform temperature distribution. These results indicate that the hybrid nanofluids, especially Silver-Gold, may have enormous potential in biomedical applications like hyperthermia treatment, drug delivery, and vascular heat management. This study bridges critical gaps in understanding hybrid nanofluid dynamics in stenosed arteries, providing a foundation for future innovations in biomedical heat transfer and fluid mechanics.</div></div>","PeriodicalId":17428,"journal":{"name":"Journal of thermal biology","volume":"127 ","pages":"Article 104060"},"PeriodicalIF":2.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143181565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surviving in the urban jungle: The role of foam nests as thermal insulator in Pleurodema borellii (anura: Leptodactylidae)","authors":"Ana Boggio,&nbsp;Laura Pereyra","doi":"10.1016/j.jtherbio.2024.104022","DOIUrl":"10.1016/j.jtherbio.2024.104022","url":null,"abstract":"<div><div>Urbanisation stands as a primary driver of biodiversity loss globally, reshaping natural landscapes and imposing novel environmental conditions upon organisms. This ecological novelty poses challenges, and species capable of thriving in urban environments are considered tolerant. Among vertebrates, anurans are the most susceptible to land-use changes, mainly due to their life history and morphological traits. They exhibit a great diversity of reproductive strategies and modes, among which the foam nest plays several important roles, such as moderating or buffering adverse conditions. In this study, we assessed the foam nest of <em>Pleurodema borellii</em>, an urban tolerant species, as a potential thermal insulator in the city of San Salvador de Jujuy, Argentina. We carried out our surveys within San Salvador and surrounding areas, focusing on urban and peri-urban environments. We measured the height, length, and internal temperature of 48 foam nests, as well as the temperature of their immediate environment (water and air at one cm above the nest), over consecutive days from the first day until the nest disappeared. Finally, we collected four to five embryos from each foam nest once a day to identify their developmental stage. Our results suggest that foam nests not only mitigate low temperatures but also buffer against the heat of urban environments. These findings suggest that the foam nest could be one of the traits that facilitates the occurrence of this anuran species in the city and therefore may explain its tolerance to urbanisation.</div></div>","PeriodicalId":17428,"journal":{"name":"Journal of thermal biology","volume":"127 ","pages":"Article 104022"},"PeriodicalIF":2.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142828774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Scientific knowledge about gene expression in ruminants under heat stress - A scientometric review","authors":"Marina Wust Vasconcelos ,&nbsp;Julia Morgana Vieira Dada ,&nbsp;Vitória Alves Pereira ,&nbsp;Ali Zandi-Karimi ,&nbsp;Nédia de Castilhos Ghisi ,&nbsp;Flavia Regina Oliveira De Barros","doi":"10.1016/j.jtherbio.2024.104028","DOIUrl":"10.1016/j.jtherbio.2024.104028","url":null,"abstract":"<div><div>Heat stress can alter the expression of genes in the individual's molecular response. The identification of these genes makes it possible to better understand the molecular response, identifying biomarker genes and indirect response pathways that can help with genetic improvement studies, animal welfare, separating more thermotolerant varieties and mitigating the effects of heat stress. The aim of this scientometric review was to characterize the state of the art of scientific research into gene expression in ruminants under heat stress, to define the most studied species, biology systems and genes, as well as the related biological pathways and processes. The articles for the dataset were compiled in the Web of Science database, refined individually and analyzed using the CiteSpace, RStudio, Excel and GraphPad Prism programs and the KEGG (Kyoto Encyclopedia of Genes and Genomes) database. The publications formed a data set containing 271 articles and an H-index of 37. The number of publications increased from 2011. The countries with the highest frequency of publications are India, the United States, China and Brazil, the ruminant species are cattle, buffaloes, sheep and goats, all zootechnical interest, and biology systems was reproduction, blood and lactation, due to the economic importance of the quality and quantity of production, to the ease of collecting and possibility of studies <em>in vitro</em>. Cattle have been extensively studied in comparison to other ruminants. The HSP70 gene has been the most studied, followed by the HSP family, HSF, BAX, TLR and BCL-2, these genes can be molecular markers of heat stress. The main pathways and biological processes of genes were in cattle the cancer pathway; in goats the Mixed, incl. myd88-dependent toll-like receptor signaling pathway, and lipopolys; in sheep the oxidoreductase; and in buffalo it was the BCL-2 family. The molecular responses are still recent and have not been established.</div></div>","PeriodicalId":17428,"journal":{"name":"Journal of thermal biology","volume":"127 ","pages":"Article 104028"},"PeriodicalIF":2.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142894975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pomegranate peels ethanolic extract in free and nanoemulsified forms around mating and early pregnancy differently affect heat tolerance capacity and reproductive performance of ewes under heat stress","authors":"Nesrein M. Hashem,&nbsp;Zahraa R. Abo-elezz","doi":"10.1016/j.jtherbio.2024.104043","DOIUrl":"10.1016/j.jtherbio.2024.104043","url":null,"abstract":"<div><div>Global warming is seriously threatening sheep farmings by increasing health problems and decreasing reproductive efficiency. In this study, pomegranate peels ethanolic extract (Ppee), rich in phenolic acids, was prepared in free (Fppee) and nanoemulsified (Nppee, with 18.49 nm–21.8 nm particles size) forms. The protective role of the extracts against heat stress impacts on homeothermy, metabolism and redox status, and reproductive performance of ewes was studied. A total of 36 Barki ewes were synchronized to estrus using two intramuscular injections PGF_2α. On the day of the first PGF_2α, ewes were allocated into three homogeneous experimental groups and received 300 mg/ewe/day Fppee, 300 mg/ewe/day Nppee, or not (control) until day 35 post-mating. The Fppee ewes showed the highest homeothermy in the morning, whereas the Nppee ewes showed the lowest homeothermy in the afternoon (<em>P</em> &lt; 0.001). Both extracts increased plasma total protein, glucose, total antioxidant capacity, and glutathione concentrations (<em>P</em> &lt; 0.001), whereas they decreased plasma urea, cholesterol, and malondialdehyde concentrations compared to control (<em>P</em> &lt; 0.001). The highest and lowest values of these variables were for the Nppee ewes. The Nppee ewes had the significant lowest plasma progesterone concentrations. There were no differences in corpora lutea numbers and diameters. Lambs born to Fppee ewes had the highest birth weights and survivability. In conclusion, supplementing heat-stressed ewes with Fppee improved homeothermy, metabolism, redox status, and lamb weight and survivability without hampering reproductive performance, mainly by decreasing progesterone concentrations as observed in Nppee ewes.</div></div>","PeriodicalId":17428,"journal":{"name":"Journal of thermal biology","volume":"127 ","pages":"Article 104043"},"PeriodicalIF":2.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142927410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors influencing scrotal temperature in the bull during simulated heat treatments and thermoneutral conditions as determined by multimodel inferencing","authors":"A.L. Wallage ,&nbsp;A.M. Lees ,&nbsp;A.T. Lisle ,&nbsp;J.C. Lees ,&nbsp;S.D. Johnston ,&nbsp;J.B. Gaughan","doi":"10.1016/j.jtherbio.2024.104037","DOIUrl":"10.1016/j.jtherbio.2024.104037","url":null,"abstract":"<div><div>The creation of any model is complex requiring vast amounts of data, typically gathered over a series of experiments. Specifically the temperature humidity index (THI) and heat load index (HLI) are used as management tools to implement mitigation strategies during hot climatic conditions. Exposure of the testes to hot climatic conditions has a negative impact on spermatogenesis in the bull, and other species. Despite the bull having effective scrotal thermoregulatory ability, these mechanisms can breakdown when the bull is under heat stressed causing scrotal temperature to increase. The ability to understand the effect climatic conditions have on scrotal temperature could be a valuable tool for producers. Six Wagyu bulls were exposed to series of heat treatments, acute and chronic with thermoneutral periods in between, in climate controlled rooms. Abdominal and scrotal temperature were continuously recorded via surgically implanted data loggers. Ambient temperature (AT) and relative humidity (RH) throughout the same periods were monitored. An information theoretic approach was used to analyse the data. Data were split into three groups, one for each of the ambient conditions of acute, chronic and thermoneutral. A global model for each of these groups was constructed using generalised additive models and included all parameters of interest; abdominal temperature, AT, RH and THI. Additional candidate models consisting of subsets of these global models were run for each acute, chronic and thermoneutral. Models were statistically compared and multimodel inferencing used to determine the effect these parameters had on scrotal temperature. The best model for acute included abdominal temperature, RH and an autoregressive factor (AR(1)) whilst the best model for both chronic and thermoneutral included just abdominal temperature and AR(1). Adding abdominal temperature to the model for the acute and chronic treatments improved the model strength with an increase in abdominal temperature increasing scrotal temperature. In contrast, the addition of abdominal temperature to the thermoneutral models did not consistently improve their strength. Despite a small sample size, the data indicates that scrotal temperature can be modelled. The addition of future observations to these models will continue to strengthen models, improving their usability.</div></div>","PeriodicalId":17428,"journal":{"name":"Journal of thermal biology","volume":"127 ","pages":"Article 104037"},"PeriodicalIF":2.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142971583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}