Journal of thermal biology最新文献

{"title":"Machine learning in multi-spectral thermal imaging for enhanced detection of neurological disorders through thermoplasmonics","authors":"P. Anu ,&nbsp;Priti Sharma ,&nbsp;Harish Kumar ,&nbsp;Neetu Sharma ,&nbsp;Priyanka Rani ,&nbsp;K. Immanuvel Arokia James","doi":"10.1016/j.jtherbio.2025.104102","DOIUrl":"10.1016/j.jtherbio.2025.104102","url":null,"abstract":"<div><div>Thermal imaging is employed as a non-invasive diagnosing instrument in various medical practices, especially neurology. This paper delineates a systematic methodology for the development and evaluation of a multi-spectral thermal imaging system for detecting neurological diseases.</div><div>The proposed methodology incorporates three spectral types, specifically Long-Wave Infrared (LWIR), Mid-Wave Infrared (MWIR), and Near-Infrared (NIR), along with artificial neural networks (ANNs). This comprehensive integration enables several critical capabilities: First, the imaging of both surface and the deep tissues’ temperature changes, offering information about the neural activity at varying depths. Second, it enables the identification of low-contrast temperature changes detected with high-resolution. Third, it facilitates measuring the level of neural activity based on the thermal profile data.</div><div>This system demonstrates outstanding diagnostic metrics, such as an AUC of 0.923 (95 % CI: in addition, the specificity index is 0, and sensitivity ranges from 0.897 to 0.949, and the F1 score ranges from 0.891 to 0.917), rendering it clinically viable. It also achieved a moderate diagnostic accuracy of approximately 88.6 % for various neurological disorders.</div><div>This study contributes towards the further advancement of thermal imaging technology for diagnosing neurological disorders in more efficient and non-invasive manners, thereby enhancing the early screening potential for various neurological pathologies.</div></div>","PeriodicalId":17428,"journal":{"name":"Journal of thermal biology","volume":"129 ","pages":"Article 104102"},"PeriodicalIF":2.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143828371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A phenological shift to save the boys? Current and projected trends of hatchling sex ratio of the loggerhead turtle Caretta caretta at Dalyan Beach, Türkiye","authors":"Jay Kirkham ,&nbsp;Dogan Sözbilen ,&nbsp;Arzu Kaska ,&nbsp;Çisem Sezgin ,&nbsp;Yakup Kaska","doi":"10.1016/j.jtherbio.2025.104091","DOIUrl":"10.1016/j.jtherbio.2025.104091","url":null,"abstract":"<div><div>Dalyan beach, Mugla, Türkiye hosts one of the largest loggerhead turtle rookeries in the Mediterranean. The sex of marine turtles, like many reptile species, is influenced by incubation temperature, with the threat of climate change looming increasing temperatures across the world may lead to an imbalance in the sex ratio of turtle populations. Over a ten-year study period (2012–2021), temperature dataloggers (n = 497) were placed during or the morning after ovipositioning. Using middle third of incubation as a proxy for the thermosensitive period and subsequent application of the Hill Equation, this study estimates the current and projected cohort sex ratios for Dalyan beach. The estimated overall male ratio over the ten-year study period was 25.7 % ± 23.3, with considerable interannual variation when data were compared from overlapping dates. Using the observed data, a GAM was built to predict nesting temperature using archived climate data, which explained 66.7 % of the variance. This model was applied to future projections of temperature using IPCC climate change scenario SSP 3–7.0, which resulted in a significant decrease in male ratio compared in the near term (2021–2040) 17.2 % ± 0.6 s d, mid-term (2041–2060) 14 % ± 0.5 s d and far term (2081–2100) 10.7 %. A hypothetical 10-day shift of nesting phenology would quell the effects of warming and maintain or increase current male ratio in the near term 25.6 % ± 0.8 s d. A 20-day shift would have the same effect in the near term (37.3 % ± 0.9 s d) and mid-term (31.4 % ± 0.9 s d) projections. These nesting grounds are important to the sustained survival of the species and while this study indicates restorative potential to the sex imbalance, a reliance on the development of such a phenological shift is less than favourable. While climate change projections vary between models, a situation that gives enough buffering time is unlikely, and feminisation of the population seems inevitable without further action.</div></div>","PeriodicalId":17428,"journal":{"name":"Journal of thermal biology","volume":"129 ","pages":"Article 104091"},"PeriodicalIF":2.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143739525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mapping the influence of spatiotemporal distribution of skin contact temperature on perceived thermal sensation in human fingers","authors":"Jinu Sudhakaran ,&nbsp;Jung Kyung Kim","doi":"10.1016/j.jtherbio.2025.104108","DOIUrl":"10.1016/j.jtherbio.2025.104108","url":null,"abstract":"<div><div>The temperature distribution upon direct skin contact with a hot solid surface plays a critical role in the resulting human physiological response as it influences both thermal sensation and pain perception. This study aims to advance understanding regarding the skin contact temperature (T_SC) and its spatial distribution on the skin surface upon direct contact with a hot solid surface maintained at a fixed temperature (T_H) ranging from 50 to 70 °C, using an innovative visualization technique under controlled thermal conditions with human subjects. Results highlight significant gender-based differences in changes in the spatial summation of T_SC, with male subjects exhibit an average of 4.2 °C higher than that of female subjects at elevated T_H levels, while females adapt faster, resulting in longer pain onset times. Additionally, this study explores the effects of skin properties, specifically skin thickness and skin viscoelasticity, on changes in the spatial summation temperature (delta T_SC,S) and thermal sensitivity; the findings demonstrate limited influence at moderate T_H, with marginal effects at higher T_H. These insights have significant implications for the design and development of safer prosthetics, thermal devices, and haptic technologies. By establishing guidelines such as maintaining the delta T_SC,S value below 10 °C to mitigate pain onset, this research provides critical parameters for creating systems that accurately mimic human physiological responses to thermal input. Future studies should explore these thermal psychophysical responses across diverse populations and dynamic conditions to broaden the applicability of the insights gained by the present work.</div></div>","PeriodicalId":17428,"journal":{"name":"Journal of thermal biology","volume":"129 ","pages":"Article 104108"},"PeriodicalIF":2.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143785873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of duration and type of cold acclimation on the subsequent cold tolerance of a tenebrionid beetle","authors":"Samira Khodayari ,&nbsp;Stéphane A.P. Derocles ,&nbsp;David Renault","doi":"10.1016/j.jtherbio.2025.104100","DOIUrl":"10.1016/j.jtherbio.2025.104100","url":null,"abstract":"<div><div>The effects of cold acclimation on the subsequent survival and recovery of cold-exposed adults of <em>Alphitobius diaperinus</em> (Coleoptera: Tenebrionidae) was examined. Acclimation conditions were: 1, 2, 4 and 8 days at 5, 10, 15, 25 °C and fluctuating temperatures of 5–10-15 °C (8:8:8 h). Acute and chronic cold stresses were induced by keeping beetles at −8 °C for 8 h and 0 °C for 2, 3, 4, 5 and 6 days respectively. Survival was recorded after 5 days of recovery at 25 °C. The insects acclimated to 5, 10, 15 and 25 °C for 1 and 4 days were selected for metabolic response studies which was performed by gas chromatography-mass spectrophotometry (GC-MS). Beetles acclimated at 25 °C (control) and beetles acclimated at 5 °C for 1 or 8 days did not survive after acute cold stress. Survival increased to 100 % after acute cold stress in beetles acclimated to fluctuating temperatures for 2 days. The lethal times for 50 % of the population (Lt₅₀) were calculated for beetles after chronic cold stress and range from 4.89 days in beetles acclimated to fluctuating temperatures for 4 days–0.018 days in beetles acclimated to 5 °C for 8 days. The metabolic profile analysis showed that proline exhibited the highest concentration in all experimental groups. Increases of alanine and glycine in cold acclimated beetles were observed. Glutamic acid had opposite pattern and decreased significantly in acclimated beetles at 5 °C for 4 days. Alanine accumulation and glutamic acid decrease suggest that alanine has derived from transamination of glutamic acid and pyruvate. Erythritol, sorbitol, arabitol, adonitol, xylitol, glucose and maltose were the polyols and sugars that have been accumulated in cold acclimated beetles especially at 5 °C. Mannose has only accumulated in 1d acclimated beetles.</div></div>","PeriodicalId":17428,"journal":{"name":"Journal of thermal biology","volume":"129 ","pages":"Article 104100"},"PeriodicalIF":2.9,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143823354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to \"How plastic are upper thermal limits? A comparative study in tsetse (family: Glossinidae) and wider Diptera\" [J. Therm. Biol. 118 (2023) 103745].","authors":"Hester Weaving, John S Terblanche, Sinead English","doi":"10.1016/j.jtherbio.2025.104096","DOIUrl":"https://doi.org/10.1016/j.jtherbio.2025.104096","url":null,"abstract":"","PeriodicalId":17428,"journal":{"name":"Journal of thermal biology","volume":" ","pages":"104096"},"PeriodicalIF":2.9,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143743256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validating thermal refuge-seeking behaviour in zebrafish (Danio rerio) during acute thermal challenge","authors":"E.A. Dodsworth ,&nbsp;B.L. Firth ,&nbsp;P.M. Craig","doi":"10.1016/j.jtherbio.2025.104094","DOIUrl":"10.1016/j.jtherbio.2025.104094","url":null,"abstract":"<div><div>Ectotherms, such as fish, are highly dependent on the stability of their environment to regulate body temperature, performance, and metabolism. Increasing temperatures cause behavioural changes in fish which can be observed and used as indices for determining upper thermal limits. The thermal agitation temperature (T_ag) is a recent, and ecologically significant, sublethal index for the upper thermal limit. Previous studies have described thermal agitation as the endpoint, prior to the critical thermal maximum (CT_max), where fish start exhibiting apparent refuge-seeking and thermal avoidance behaviour. It is an assumption that fish are seeking thermal refuge at T_ag, but evidence for this is lacking. Therefore, this study aimed to validate this assumption by using zebrafish (<em>Danio rerio</em>) and providing them with thermal refuge while increasing their environment's temperature past T_ag. The behavioural responses of <em>D. rerio</em> were observed and their spatial movements were tracked using the animal-tracking software, AnimalTA. The analysis from this study indicated that refuge is sought out prior to T_ag and distance between shoal members increases after T_ag, indicating <em>D. rerio</em> may trade-off the protective value of a shoal to search for thermal refuge. Our study demonstrates that with refuge available, <em>D. rerio</em> can surpass T_ag until refuge itself exceeds T_ag, validating that agitation is refuge-seeking behaviour, but a mechanism of last resort. This insight improves our understanding of fish responses to thermal stress and emphasizes the value of using T_ag as a sublethal metric alongside CT_max in thermal tolerance studies, with potential applications in ecology and conservation contexts.</div></div>","PeriodicalId":17428,"journal":{"name":"Journal of thermal biology","volume":"129 ","pages":"Article 104094"},"PeriodicalIF":2.9,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143670213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing the link between skin Aquaporins and morphological attributes under simulated heat stress conditions: A comparative investigation between hair and wool sheep breeds","authors":"Emad M. Samara ,&nbsp;Majdi A. Bahadi ,&nbsp;Muhammed A. Khan ,&nbsp;Muhammed Afzal ,&nbsp;Mohammed A. Al-Badwi ,&nbsp;Khalid A. Abdoun ,&nbsp;Salem S. Alghamdi ,&nbsp;Ahmed A. Al-Haidary","doi":"10.1016/j.jtherbio.2025.104095","DOIUrl":"10.1016/j.jtherbio.2025.104095","url":null,"abstract":"<div><div>A comprehensive understanding of the functions of Aquaporins (AQPs) is indispensable for elucidating physiological adjustments to varied habitats and addressing water balance complexities amid environmental fluctuations. This experiment endeavors to investigate the relationship between cutaneous AQPs and morphological traits in two sheep breeds with differing haircoat textures, the Naimi and Najdi, under simulated heat stress conditions. Ten male lambs from each breed were housed individually in controlled environments and subjected to cyclic heat stress mimicking summer conditions for six weeks. Sweating rates (SR) were measured biweekly, and skin and coat samples were collected for analysis in the final week. Additionally, the mRNA expression levels of Aquaporin 1 (<em>AQP1</em>), Aquaporin 3 (<em>AQP3</em>), and Aquaporin 5 (<em>AQP5</em>) in skin tissue were assessed. Results showed a (<em>P</em> &lt; 0.05) increase in skin <em>AQPs</em> gene expression following thermal exposure in both breeds, accompanied by elevated SR. However, the Naimi breed exhibited (<em>P</em> &lt; 0.05) higher <em>AQP1</em> expression levels, correlating with differences in their skin depth, coat thickness, and fleece density compared to the Najdi breed, which showed (<em>P</em> &lt; 0.05) heightened <em>AQP5</em> expression, consistent with their thicker hair diameter. Both breeds displayed similar upregulation of <em>AQP3,</em> suggesting its equivalent role in facilitating perspiration during heat stress. In conclusion, this experiment represents one of the initial inquiries into the presence of <em>AQPs</em> genes within the dermal layers of sheep. The involvement of both skin <em>AQPs</em> and sweating response might emphasizes the intricate interplay between their physical attributes and genetic predispositions in coping with heat stress, indicating a multifaceted process of thermoregulation in sheep. The obtained findings underscore the role of AQPs in helping sheep breeds with distinct coat textures adapt to environmental challenges and maintain water balance, and thus might support targeted breeding strategies for enhanced heat tolerance in arid environments.</div></div>","PeriodicalId":17428,"journal":{"name":"Journal of thermal biology","volume":"129 ","pages":"Article 104095"},"PeriodicalIF":2.9,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interspecies differences in lactate dehydrogenase and citrate synthase activity among damselfish and cardinalfish","authors":"Elliott Schmidt ,&nbsp;Hunter Milles ,&nbsp;Lauren Kennedy ,&nbsp;Jennifer Donelson","doi":"10.1016/j.jtherbio.2025.104089","DOIUrl":"10.1016/j.jtherbio.2025.104089","url":null,"abstract":"<div><div>Species with different thermal distributions, life-history traits, and behaviours have evolved physiological processes to suit energetic demands. Previous research has argued that these interspecies differences are often reflected in muscle enzyme activity that serve as proxies for aerobic and anaerobic respiration. Here, we measured the maximal enzyme activity of two enzymes, citrate synthase and lactate dehydrogenase, between two damselfish (<em>Pomacentrus</em>) and cardinalfish (<em>Ostorhinchus</em>) species. Citrate synthase was measured as a proxy for mitochondrial volume density, a marker of aerobic metabolism; lactate dehydrogenase was measured as a proxy for anaerobic energy production, a marker for anaerobic metabolism. Thermal performance curves of maximal enzyme activity were measured from 10 to 50 °C, at 10 °C intervals. Citrate synthase and lactate dehydrogenase both showed a positive correlation with temperature, that was absent of a plateau. Damselfish displayed higher levels of citate synthase maximal enzyme activity, while cardinalfish displayed a higher lactate dehydrogenase to citrate synthase ratio. <em>Ostorhinchus doederleini,</em> a sedentary cardinalfish, displayed higher level of lactate dehydrogenase maximal enzyme activity. Temperature coefficients (Q10) for lactate dehydrogenase showed a curved relationship, peaking at differences between 30 and 40 °C. No differences in Q10 values were observed between species, suggesting no difference in the thermal sensitivity of enzymes. Interspecies differences in maximal enzyme activity identified in this study compliments previous research, whereby more active species require higher levels of citrate synthase to fuel sustained swimming, as well as energetically demanding locomotion behaviours. Alternatively, more sedentary species possessed higher levels of lactate dehydrogenase and reliance on anaerobic metabolism, possibly due to an increased reliance on infrequent burst swimming behaviours.</div></div>","PeriodicalId":17428,"journal":{"name":"Journal of thermal biology","volume":"129 ","pages":"Article 104089"},"PeriodicalIF":2.9,"publicationDate":"2025-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pre hospital emergency medical dispatches following heat waves: A systematic review study and meta-analysis","authors":"Ali Hosseinzadeh ,&nbsp;Hamidreza Aghababaeian ,&nbsp;Abbas Ostadtaghizadeh ,&nbsp;Mostafa Hadei ,&nbsp;Fateme Yazdi ,&nbsp;Ali Asgary ,&nbsp;Carolyn Stephens ,&nbsp;Elahe Mombeni ,&nbsp;Ahmadreza Khosravi Far","doi":"10.1016/j.jtherbio.2025.104086","DOIUrl":"10.1016/j.jtherbio.2025.104086","url":null,"abstract":"<div><div>Given that climate change is a global phenomenon influencing various aspects of health, this study aimed to conduct a systematic review and meta-analysis of the effects of heat waves on pre-hospital emergency medical dispatches (EMDs) worldwide. This study was conducted in accordance with the PRISMA guidelines. Relevant English-language studies were searched using specific keywords related to “heat wave, EMDs, and health” in reputable databases such as Scopus, PubMed, and WoS from the inception of each database until December 2024. The selection of related studies was based on screening the title, abstract, and full text. Two researchers independently identified studies according to predefined inclusion and exclusion criteria. Out of 494 identified studies, 20 papers were evaluated. A random-effects model or a fixed-effects model was chosen based on the heterogeneity criterion. Publication bias was assessed using a funnel plot and Egger's test. The overall results of the meta-analysis indicated that heat waves, considering the 99th and 95th percentiles of temperature, are significantly associated with an increase in EMDs, with RRs of 1.11 (95% CI: 1.06, 1.15) and 1.09 (95% CI: 1.05, 1.13), respectively. Additionally, heat waves significantly affect the number of EMDs for middle-aged and elderly individuals, with RRs of 1.48 (95% CI: 1.18, 1.78) and 1.19 (95% CI: 1.14, 1.24), respectively. The overall results of the meta-analysis indicated that heat waves, considering the 95th and 99th percentiles of temperature, are significantly associated with an increase in EMDs due to cardiovascular diseases, with RRs of 1.054 (95% CI: 1.009, 1.100) and 1.038 (95% CI: 1.000, 1.075), respectively. Given the increasing trend of global warming and the subsequent rise in the incidence and intensity of heat waves, the pre-hospital medical emergency system must be prepared to respond appropriately to such events.</div></div>","PeriodicalId":17428,"journal":{"name":"Journal of thermal biology","volume":"129 ","pages":"Article 104086"},"PeriodicalIF":2.9,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143549292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative transcriptome analyses reveal the acute heat stress response of a cool-temperate shrimp Fenneropenaeus chinensis","authors":"Haochen Zhu ,&nbsp;Xiaojun Zhang ,&nbsp;Xiaoxi Zhang ,&nbsp;Jianbo Yuan ,&nbsp;Zhenxia Sha ,&nbsp;Fuhua Li","doi":"10.1016/j.jtherbio.2025.104087","DOIUrl":"10.1016/j.jtherbio.2025.104087","url":null,"abstract":"<div><div>Temperature is a critical environmental factor in ecosystems, and understanding the integrated response of different tissues to heat stress is essential for elucidating the study, we conducted a comparative transcriptome analysis of three tissues, hepatopancreas, gill, and muscle, of the Chinese shrimp (<em>Fenneropenaeus chinensi</em>s) under heat stress conditions. The results reveal that the three tissues exhibit distinct gene expression patterns, which may imply a certain degree of interaction or coordination among them. Specifically, under heat stress, genes related to amino acid synthesis and utilization were down-regulated in both hepatopancreas and gill, leading to the inhibition of various metabolic pathways including carbohydrates, lipids, amino acids, and nucleic acid metabolism. However, in the muscle, genes related to protein synthesis and energy-consuming processes, including heat shock proteins (HSPs) and muscle proteins, were up-regulated accompanied by an increase in protein content. In the gill, 16.2% of the differentially expressed genes (DEGs) which were related to the cytoskeleton were significantly down-regulated. These results suggest that, in the hepatopancreas and gill, energy flow was inhibited towards synthetic reactions, particularly amino acid synthesis, as characterized by a decrease in protein content to conserve energy. This conserved energy is then reallocated to muscle for increased protein synthesis to maintain muscle function to cope with heat stress. This research not only provides comprehensive insights into the molecular mechanisms of <em>F. chinensis</em> in response to heat stress but also lays a foundation for understanding the strategies employed by thermosensitive marine invertebrates to adapt to high temperature environments.</div></div>","PeriodicalId":17428,"journal":{"name":"Journal of thermal biology","volume":"129 ","pages":"Article 104087"},"PeriodicalIF":2.9,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143579771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}