Journal of the Neurological Sciences最新文献

{"title":"West Nile virus neuroinvasive disease: Clinical characteristics and prognostic factors","authors":"Tali Elkanovich ,&nbsp;Gal Tsur ,&nbsp;Keshet Pardo ,&nbsp;Jonathan Naftali ,&nbsp;Hadas Hodadov ,&nbsp;Nir Cafri ,&nbsp;Shelly Degani Schwalm ,&nbsp;Galit Vinokur ,&nbsp;Ilan Goldberg ,&nbsp;Oded Shor ,&nbsp;Yair Mina ,&nbsp;Eitan Auriel ,&nbsp;Felix Benninger ,&nbsp;Adi Wilf-Yarkoni","doi":"10.1016/j.jns.2025.123700","DOIUrl":"10.1016/j.jns.2025.123700","url":null,"abstract":"<div><h3>Background</h3><div>In 2024, Israel experienced its largest West Nile Virus (WNV) outbreak, with 922 confirmed cases. WNV is a leading global cause of viral encephalitis. This study aimed to identify clinical features and prognostic factors associated with neuroinvasive WNV in hospitalized patients.</div></div><div><h3>Methods</h3><div>We retrospectively reviewed hospitalized patients with confirmed WNV at a tertiary center in Israel (January–September 2024). Patients were categorized as neuroinvasive or non-neuroinvasive. Demographic, clinical, and outcome data were analyzed. Primary outcome was 16-week mortality; secondary was functional decline (modified Rankin Scale, mRS).</div></div><div><h3>Results</h3><div>Of 166 hospitalized patients, 93 (56 %) had neuroinvasive WNV, primarily encephalitis (90 %). Neuroinvasive disease was linked to higher mortality (36 % vs. 13 %, <em>p</em> &lt; 0.01) and worse functional outcomes (median mRS 4 ± 2 vs. 2 ± 2, <em>p</em> = 0.02). No significant differences in age, sex, comorbidities, or immunosuppression were found between groups. Among neuroinvasive cases, encephalitis, seizures, and autonomic dysfunction were associated with poorer outcomes. Lower pre-morbid function did not predicted greater decline. EEG in 28 encephalitis patients showed abnormalities in 71 %, mainly diffuse slowing; epileptiform activity was rare. Quantitative EEG revealed increased delta power and more frequent paroxysmal slow wave events(PSWE), which correlated with worse functional status.</div></div><div><h3>Conclusions</h3><div>Neuroinvasive WNV is associated with substantial morbidity and mortality. Traditional risk factors like age were not predictive of poor outcomes. Instead, clinical features such as autonomic dysfunction and novel markers like quantitative EEG abnormalities may serve as valuable prognostic tools. These findings underscore the need for improved risk stratification strategies in WNV neuroinvasive disease.</div></div>","PeriodicalId":17417,"journal":{"name":"Journal of the Neurological Sciences","volume":"478 ","pages":"Article 123700"},"PeriodicalIF":3.2,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145096803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical features and prognosis of postpartum lower extremity nerve injury: A four-year single-center experience in Israel","authors":"Emily Lebedkin ,&nbsp;Shlomi Shmuel ,&nbsp;Arava Nir ,&nbsp;Itzhak Kimiagar ,&nbsp;Shlomi Peretz ,&nbsp;Gilad Kenan","doi":"10.1016/j.jns.2025.123698","DOIUrl":"10.1016/j.jns.2025.123698","url":null,"abstract":"<div><h3>Background</h3><div>Postpartum lower extremity nerve injury (LENI) is a recognized but often underdiagnosed complication of childbirth, presenting with symptoms ranging from transient sensory disturbances to persistent motor deficits. Although the reported incidence is low, research on the topic remains limited, and no studies to date have examined this phenomenon in the Israeli population.</div></div><div><h3>Methods</h3><div>A retrospective review was conducted of 531 neurological consultations from the maternity ward at Shamir Medical Center between 2019 and 2022. Cases of suspected LENI – postpartum leg weakness, paresthesia, or difficulty walking - were further analysed. Clinical data, delivery characteristics, and electrophysiological findings were reviewed.</div></div><div><h3>Results</h3><div>Among 33,404 deliveries during the study period, 23 cases of suspected LENI were identified (0.069 %). Most women (61 %) presented with isolated sensory symptoms, primarily in the distribution of the lateral femoral cutaneous nerve. Nine women (39 %) exhibited motor deficits, predominantly following vaginal deliveries with epidural anaesthesia. In 67 % of motor cases, symptoms affected the right side. While most patients experienced full recovery within weeks, 22 % reported persistent symptoms at follow-up.</div></div><div><h3>Conclusion</h3><div>LENI is a rare complication of childbirth, generally associated with a favorable prognosis. The observed incidence at Shamir Medical Center was low, possibly reflecting underdiagnosis of milder cases. This is the first study to characterize postpartum LENI in the Israeli population. A prospective study is planned to further elucidate its pathophysiology and risk factors.</div></div>","PeriodicalId":17417,"journal":{"name":"Journal of the Neurological Sciences","volume":"478 ","pages":"Article 123698"},"PeriodicalIF":3.2,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145091977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multimodal MRI analysis selecting key brain features for machine learning based classification of diabetic neuropathic pain and phenotypes","authors":"Søren NF. Hostrup ,&nbsp;Henrik P. Lind ,&nbsp;Suganthiya S. Croosu ,&nbsp;Johan Røikjer ,&nbsp;Carsten D. Mørch ,&nbsp;Niels Ejskjær ,&nbsp;Lasse R. Østergaard ,&nbsp;Tine M. Hansen ,&nbsp;Jens B. Frøkjær","doi":"10.1016/j.jns.2025.123701","DOIUrl":"10.1016/j.jns.2025.123701","url":null,"abstract":"<div><div>Cerebral alterations are associated with diabetic peripheral neuropathy (DPN) and neuropathic pain, including reductions in brain volumes, cortical thickness, sulcus depth, and alterations in metabolites and functional connectivity. This study combined multimodal magnetic resonance imaging (MRI) data to differentiate clinical phenotypes and uncover distinct associated brain features using machine-learning based classification. Seventy-six participants were recruited: 20 healthy and 56 with type 1 diabetes mellitus: 18 without DPN, 19 with painless DPN, and 19 with painful DPN. Three machine learning classifiers were evaluated, including accompanying feature importance from the highest performing classifier. Class membership probabilities (predicted probability of belonging to a group) were compared across classes and correlated with clinical measures of pain and nerve function for the class concerned. Accuracies were ≥ 0.75 for all classes except painless DPN, though separated by painful membership probability (<em>p</em> ≤ 0.02). Overall classification accuracy was 0.71. The most informative features were functional connectivity, followed by <em>N</em>-acetylaspartate/creatine and sulcal depth. The painful DPN group was separated from the remaining groups by painful membership probability (<em>p</em> ≤ 0.01), which correlated with pain measures. Diabetes without DPN membership probability correlated with sural nerve conduction (<em>p</em> ≤ 0.001, <span><math><msub><mi>r</mi><mi>s</mi></msub></math></span>≥0.49) and warm detection thresholds (<em>p</em> ≤ 0.001, <span><math><msub><mi>r</mi><mi>s</mi></msub></math></span>= − 0.51). This exploratory study suggests that different MRI modalities provide complementary information describing phenotypes of diabetes, DPN and DPN related pain, with functional connectivity being most essential. Thus, implying a multifactorial cerebral manifestation of neuropathy and pain in diabetes and aiding the development of grading and prognostic tools for personalised treatments. Studies of larger cohorts should validate these findings.</div></div>","PeriodicalId":17417,"journal":{"name":"Journal of the Neurological Sciences","volume":"478 ","pages":"Article 123701"},"PeriodicalIF":3.2,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145106201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characteristics and causes of recurrent ischemic events in minor ischemic stroke and TIA in the READAPT study.","authors":"Federico De Santis, Matteo Foschi, Michele Romoli, Tiziana Tassinari, Valentina Saia, Silvia Cenciarelli, Chiara Bedetti, Chiara Padiglioni, Bruno Censori, Valentina Puglisi, Luisa Vinciguerra, Maria Guarino, Valentina Barone, Maria Luisa Zedde, Ilaria Grisendi, Marina Diomedi, Maria Rosaria Bagnato, Marco Petruzzellis, Domenico Maria Mezzapesa, Pietro Di Viesti, Vincenzo Inchingolo, Manuel Cappellari, Mara Zenorini, Paolo Candelaresi, Vincenzo Andreone, Giuseppe Rinaldi, Alessandra Bavaro, Anna Cavallini, Stefan Moraru, Pietro Querzani, Maria Grazia Piscaglia, Valeria Terruso, Marina Mannino, Umberto Scoditti, Alessandro Pezzini, Giovanni Frisullo, Francesco Muscia, Maurizio Paciaroni, Maria Giulia Mosconi, Andrea Zini, Ruggiero Leone, Carmela Palmieri, Letizia Maria Cupini, Michela Marcon, Rossana Tassi, Enzo Sanzaro, Cristina Paci, Giovanna Viticchi, Daniele Orsucci, Anne Falcou, Simone Beretta, Roberto Tarletti, Patrizia Nencini, Eugenia Rota, Federica Nicoletta Sepe, Delfina Ferrandi, Luigi Caputi, Gino Volpi, Salvatore La Spada, Mario Beccia, Claudia Rinaldi, Vincenzo Mastrangelo, Francesco Di Blasio, Paolo Invernizzi, Giuseppe Pelliccioni, Maria Vittoria De Angelis, Laura Bonanni, Giampietro Ruzza, Emanuele Alessandro Caggia, Monia Russo, Agnese Tonon, Maria Cristina Acciarri, Sabrina Anticoli, Cinzia Roberti, Giovanni Manobianca, Gaspare Scaglione, Francesca Pistoia, Alberto Fortini, Antonella De Boni, Alessandra Sanna, Alberto Chiti, Leonardo Barbarini, Marcella Caggiula, Maela Masato, Massimo Del Sette, Francesco Passarelli, Maria Roberta Bongioanni, Danilo Toni, Stefano Ricci, Eleonora De Matteis, Simona Sacco, Raffaele Ornello","doi":"10.1016/j.jns.2025.123641","DOIUrl":"10.1016/j.jns.2025.123641","url":null,"abstract":"<p><strong>Background and purpose: </strong>Understanding the causes of recurrent ischemic events in patients with minor stroke or high-risk TIA is crucial to understand unmet needs in secondary prevention. This study examines the characteristics and causes of recurrences after non-cardioembolic minor stroke/high-risk TIA in patients treated with the best medical care.</p><p><strong>Methods: </strong>This subgroup analysis from a prospective real-world study (READAPT, NCT05476081) included patients with non-cardioembolic minor ischemic stroke (NIHSS ≤5) or TIA (ABCD² score ≥ 4), receiving short-term DAPT. We described the etiologic distribution according to the Trial of ORG 10172 in Acute Stroke Treatment (TOAST) classification of the index and of the recurrent event. We analyzed baseline characteristics of patients with and without a 90-day ischemic recurrence to identify factors linked to recurrence.</p><p><strong>Results: </strong>Out of 1641 patients, 56 (3.4 %) had a recurrent ischemic event (35 strokes and 21 TIAs). The cause of recurrences was undetermined in 21 (37.5 %), small vessel occlusion in 18 (32.1 %), large artery atherosclerosis in 11 (19.6 %), other determined in 3 (5.4 %), and cardioembolism in 3 (5.4 %). The etiologic distribution of recurrent events differed from that of the corresponding index events (p = 0.002). Non-compliance to DAPT was more prevalent in patients with recurrences compared with those without (8.9 % vs 3.7 %, p = 0.048).</p><p><strong>Conclusions: </strong>Patients with recurrences after a minor stroke or high-risk TIA have a different etiologic distribution compared with their index events. Additionally, a lower compliance to DAPT was observed in those with recurrences, suggesting that adherence to DAPT should be encouraged to optimize the outcome of patients.</p>","PeriodicalId":17417,"journal":{"name":"Journal of the Neurological Sciences","volume":"476 ","pages":"123641"},"PeriodicalIF":3.2,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144799491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and impact of neuro-ophthalmic multimorbidity on patient disposition and outcomes","authors":"Marko (Chi-Wei) Tien ,&nbsp;Victoria Dezard ,&nbsp;Jim Xie ,&nbsp;David Rabinovitch ,&nbsp;Tasha Miller ,&nbsp;Jonathan Micieli ,&nbsp;Edward Margolin","doi":"10.1016/j.jns.2025.123699","DOIUrl":"10.1016/j.jns.2025.123699","url":null,"abstract":"<div><h3>Purpose</h3><div>As neuro-ophthalmologists often deal with uncommon disorders, the prevalence of comorbid neuro-ophthalmic diseases is unknown. This study sought to characterize the prevalence of patients diagnosed with at least two separate neuro-ophthalmologic disorders and the impact on patient disposition and outcome as of identifying the secondary diagnosis.</div></div><div><h3>Methods</h3><div>Retrospective chart review at two university-affiliated neuro-ophthalmic practices between July–December 2023. Sociodemographic and clinical characteristics were compared between patients with and without neuro-ophthalmic comorbidity. Diagnostic testing, patient disposition and care outcomes were collected for each diagnosis.</div></div><div><h3>Results</h3><div>1843 patients (mean age 52.2 years, 62.6 % female) were identified, of whom 89 (4.8 %) were diagnosed with neuro-ophthalmic multimorbidity. The most common secondary diagnoses were thyroid eye disease (6.4 %), Horner's syndrome (5.3 %), pituitary macroadenoma (5.3 %), and trochlear nerve palsy (5.3 %). The most common symptoms and examination findings associated with neuro-ophthalmic multimorbidity were persistent vision loss, proptosis, optic nerve pallor, incomitant strabismus, ophthalmoparesis, and lid lag/retraction. The secondary diagnosis increased the urgency of neuro-ophthalmic follow-up or specialist referral in 16.9 % of patients (number needed to benefit [NNB] of 5.9) and changed the outcomes of 22.5 % of patients either by avoiding unnecessary testing/treatment or by directly saving vision/life (NNB of 4.5).</div></div><div><h3>Conclusion</h3><div>One in 21 patients referred for neuro-ophthalmic consultation was diagnosed with at least two separate neuro-ophthalmic conditions. Even within neuro-ophthalmology, a field that deals primarily with rare diseases, one must consider the possibility of multiple comorbidities when a patient's clinical presentation is atypical or inconsistent with the expected disease course.</div></div>","PeriodicalId":17417,"journal":{"name":"Journal of the Neurological Sciences","volume":"478 ","pages":"Article 123699"},"PeriodicalIF":3.2,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145096802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The missing piece: Integrating health-related quality of life in Telerehabilitati","authors":"Jati Rinakri Atmaja ,&nbsp;Palasara Brahmani Laras ,&nbsp;Hendra Pribadi ,&nbsp;Agustinus Hary Setyawan ,&nbsp;Dangin ,&nbsp;Arizona ,&nbsp;Eka Yulia Khoerunnisa","doi":"10.1016/j.jns.2025.123693","DOIUrl":"10.1016/j.jns.2025.123693","url":null,"abstract":"","PeriodicalId":17417,"journal":{"name":"Journal of the Neurological Sciences","volume":"478 ","pages":"Article 123693"},"PeriodicalIF":3.2,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145096900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Municipality-level incidence of clinically diagnosed amyotrophic lateral sclerosis, multiple sclerosis and Parkinson's disease","authors":"Jussi Sipilä M.D., Ph.D., B.Soc.Sci. ,&nbsp;Manu Jokela M.D., Ph.D. ,&nbsp;Eino Solje M.D., Ph.D.","doi":"10.1016/j.jns.2025.123696","DOIUrl":"10.1016/j.jns.2025.123696","url":null,"abstract":"<div><h3>Background</h3><div>The prevalences of Amyotrophic Lateral Sclerosis (ALS), Multiple Sclerosis (MS), and Parkinson's Disease (PD) have been shown to covary which suggests that they may share common pathogenetic factors.</div></div><div><h3>Objective</h3><div>Investigate the contemporaneous incidence patterns of ALS, MS, and PD on a municipal level in easternmost Finland.</div></div><div><h3>Methods</h3><div>Previously published ALS (years 2010–2018) and MS (years 2012–2016) cohorts were leveraged and PD data (years 2010–2018) were obtained from the national drug reimbursement entitlement registry. Population data were collected from a governmental registry.</div></div><div><h3>Results</h3><div>There were no municipalities with high incidences of all three disorders in both sexes. An ALS hotspot was observed in southeastern municipality of Tohmajärvi, driven by men. PD incidence was lowest in the central municipalities, around the urban area. Age-adjusted ALS and PD incidence was high and MS incidence low in Nurmes. Analyses of ALS and PD incidences using population aged &gt;45 as reference showed an area of low PD incidence in the westernmost municipalities but no clear ALS incidence pattern. No municipality showed a high incidence of both disorders but the ones with the highest incidences are neighboring municipalities (Tohmajärvi and Kitee) in the southern part of the province. There was no correlation between ALS and PD incidence (<em>p</em> = 0.17).</div></div><div><h3>Conclusions</h3><div>Contemporaneous incidences of ALS, MS, and PD showed no correlations. These results suggest that epidemiological research for their common pathogenic factors needs to employ very long study periods and birth cohorts in large populations. Neuropathological and/or biomarker validation of cases should also be included whenever possible.</div></div>","PeriodicalId":17417,"journal":{"name":"Journal of the Neurological Sciences","volume":"478 ","pages":"Article 123696"},"PeriodicalIF":3.2,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145086402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The gunslinger sign in sporadic Creutzfeld-Jakob disease","authors":"Manisha Coran ,&nbsp;Conor Fearon","doi":"10.1016/j.jns.2025.123692","DOIUrl":"10.1016/j.jns.2025.123692","url":null,"abstract":"","PeriodicalId":17417,"journal":{"name":"Journal of the Neurological Sciences","volume":"478 ","pages":"Article 123692"},"PeriodicalIF":3.2,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145086558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic effect of frailty in cerebral venous thrombosis","authors":"Alis J. Dicpinigaitis ,&nbsp;Fawaz Al-Mufti ,&nbsp;Christian A. Bowers","doi":"10.1016/j.jns.2025.123695","DOIUrl":"10.1016/j.jns.2025.123695","url":null,"abstract":"<div><h3>Introduction</h3><div>Few studies have evaluated the role of frailty in cerebral venous thrombosis (CVT), perhaps due to the relative rarity of the pathology and its predominance in younger populations. We aim to do so using a large, nationally representative sample.</div></div><div><h3>Methods</h3><div>Hospitalization records for CVT were identified in the National Inpatient Sample (2016–2020) and the cohort was stratified by increasing frailty thresholds, quantified by the Risk Analysis Index (RAI). Effect sizes of frailty tiers for poor outcome (defined as non-routine discharge disposition) produced from multivariable logistic regression models and discrimination (c-statistic) were evaluated.</div></div><div><h3>Results</h3><div>This analysis identified 3265 CVT hospitalizations (median age 56 years, 59.6 % female). Following cohort stratification, 465 (14.2 %) were frail and 160 (4.9 %) were very frail. A poor outcome was experienced by 58.7 %, and the rate of poor outcome as well as mean baseline NIHSS score increased as a function of increasing frailty tier. Following multivariable logistic regression analysis, all frailty tiers of the categorical RAI were significantly associated with poor outcome. A combined RAI-NIHSS model achieved a c-statistic of 0.828 (95 % CI 0.796, 0.860).</div></div><div><h3>Conclusion</h3><div>Concomitant consideration of frailty quantified by the RAI and baseline NHSS score reliably predicts short-term outcome in CVT.</div></div>","PeriodicalId":17417,"journal":{"name":"Journal of the Neurological Sciences","volume":"478 ","pages":"Article 123695"},"PeriodicalIF":3.2,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145086481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Small fiber neuropathy and COVID-19 vaccination: Methodological considerations and future directions","authors":"Christian Messina","doi":"10.1016/j.jns.2025.123694","DOIUrl":"10.1016/j.jns.2025.123694","url":null,"abstract":"","PeriodicalId":17417,"journal":{"name":"Journal of the Neurological Sciences","volume":"478 ","pages":"Article 123694"},"PeriodicalIF":3.2,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145047037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}