Journal of the Neurological Sciences最新文献

Importance of focusing on subjective symptoms to maintain quality of life in patients with Parkinson's disease for over 5 years. 关注主观症状对维持帕金森病患者 5 年以上生活质量的重要性。

IF 3.6 3区医学

Journal of the Neurological Sciences Pub Date : 2024-09-29 DOI: 10.1016/j.jns.2024.123253

Remi Morimoto, Kazuo Kitagawa, Mutsumi Iijima

{"title":"Importance of focusing on subjective symptoms to maintain quality of life in patients with Parkinson's disease for over 5 years.","authors":"Remi Morimoto, Kazuo Kitagawa, Mutsumi Iijima","doi":"10.1016/j.jns.2024.123253","DOIUrl":"https://doi.org/10.1016/j.jns.2024.123253","url":null,"abstract":"<p><p>Parkinson's disease (PD) is a neurodegenerative disorder that causes a variety of motor and non-motor symptoms (NMS), which affect the patient's quality of life (QOL). This study aimed to compare QOL and background in patients with PD based on the disease duration and investigate the factors affecting QOL. Patients with PD were evaluated based on age, sex, disease duration (≤5 years and > 5 years groups), Mini Mental State Examination (MMSE), Japanese version of Montreal Cognitive Assessment (MoCA-J), Levodopa equivalent daily dose (LEDD), Hoehn and Yahr (HY) severity, movement disorder society-sponsored revision of the unified Parkinson's disease rating scale (MDS-UPDRS) parts I-IV, and QOL using the Parkinson's disease questionnaire (PDQ-8). Overall, 102 patients with PD (58 males; mean age = 70.0 years; mean disease duration = 7.3 years) were included in this study. QOL was significantly correlated (r > 0.30, p < 0.05) with disease duration and MDS-UPDRS parts I-IV total scores. When the PDQ-8 total score was compared with MDS-UPDRS parts I-IV total scores based on disease duration classification, it was positively correlated with the scores for parts I and II in the >5 years group. Moreover, MDS-UPDRS parts I and II total scores appeared to be the factors most significantly affecting QOL. The factors affecting QOL in patients with PD were subjective NMS and motor symptoms. Since, physician-rated motor symptoms were not associated with QOL in patients with >5 years PD, subjective symptoms should be evaluated and treated to maintain QOL.</p>","PeriodicalId":17417,"journal":{"name":"Journal of the Neurological Sciences","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142365714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Response to letter from Catamo, Costa, Buque & Nzwalo (2024) titled "Possible role of mycotoxins, malnutrition and MECP2 dysregulation in nodding syndrome" regarding Spencer, Valdes Angues & Palmer's paper titled "Nodding syndrome: A role for environmental biotoxins that dysregulate MECP2 expression?" JNS. 2024;462:123077. Doi: 10.1016/j.jns.2024.123077. 对 Catamo、Costa、Buque 和 Nzwalo (2024) 题为 "霉菌毒素、营养不良和 MECP2 失调在点头综合征中的可能作用 "的信的回复，该信涉及 Spencer、Valdes Angues 和 Palmer 题为 "点头综合征：MECP2 表达失调的环境生物毒素的作用？JNS.2024;462:123077.Doi: 10.1016/j.jns.2024.123077.

IF 3.6 3区医学

Journal of the Neurological Sciences Pub Date : 2024-09-27 DOI: 10.1016/j.jns.2024.123262

Peter S Spencer, Raquel Valdes Angues, Valerie S Palmer

引用次数: 0

Bridging transdisciplinary in medical education: A pathway to achieve SDG 3 in Global Health. 医学教育中的跨学科桥梁：在全球健康领域实现可持续发展目标 3 的途径。

IF 3.6 3区医学

Journal of the Neurological Sciences Pub Date : 2024-09-27 DOI: 10.1016/j.jns.2024.123252

Samudra Mutiara Hasanah, Sri Rahayu, Oktavia Sulistina, Ronal Surya Aditya, Rizky Andana Pohan, Riza Amalia, Adellia Wardatus Sholeha

引用次数: 0

Possible role of mycotoxins, malnutrition and MECP2 dysregulation in nodding syndrome 霉菌毒素、营养不良和 MECP2 失调在结节综合征中可能起的作用

IF 3.6 3区医学

Journal of the Neurological Sciences Pub Date : 2024-09-26 DOI: 10.1016/j.jns.2024.123261

引用次数: 0

Response to the letter “Acute stroke care inequities: Cross-cultural insights and the need for multi-ethnic research” 对 "急性中风护理不平等：跨文化见解和多种族研究的必要性"。

IF 3.6 3区医学

Journal of the Neurological Sciences Pub Date : 2024-09-26 DOI: 10.1016/j.jns.2024.123257

引用次数: 0

Response to the letter “Racial and Ethnic Disparities in Acute Stroke Treatment Access: Multicultural implications in Universal Healthcare Systems” 对 "急性中风治疗中的种族和民族差异：全民医疗系统中的多元文化影响"。

IF 3.6 3区医学

Journal of the Neurological Sciences Pub Date : 2024-09-25 DOI: 10.1016/j.jns.2024.123255

引用次数: 0

Acute stroke care inequities: Cross-cultural insights and the need for multi-ethnic research. 急性中风护理的不平等：跨文化见解和多种族研究的必要性。

IF 3.6 3区医学

Journal of the Neurological Sciences Pub Date : 2024-09-25 DOI: 10.1016/j.jns.2024.123256

Riza Amalia, Ria Angin, Ahmad Razak, Sri Wahyuni Adiningtyas, Rusnila, Ethel Joy V Sebastian, Adellia Wardatus Sholeha

引用次数: 0

Racial and ethnic disparities in acute stroke treatment access: Multicultural implications in universal healthcare systems 急性中风治疗中的种族和民族差异：全民医疗系统中的多元文化影响

IF 3.6 3区医学

Journal of the Neurological Sciences Pub Date : 2024-09-24 DOI: 10.1016/j.jns.2024.123254

引用次数: 0

Impact of quality of care on outcomes in survivors of stroke with aphasia: A linked registry and hospital data observational study 护理质量对中风伴失语症幸存者预后的影响：一项关联登记和医院数据的观察研究

IF 3.6 3区医学

Journal of the Neurological Sciences Pub Date : 2024-09-21 DOI: 10.1016/j.jns.2024.123251

{"title":"Impact of quality of care on outcomes in survivors of stroke with aphasia: A linked registry and hospital data observational study","authors":"","doi":"10.1016/j.jns.2024.123251","DOIUrl":"10.1016/j.jns.2024.123251","url":null,"abstract":"<div><h3>Background</h3><div>The impact of hospital care quality on patient outcomes in post-stroke aphasia remains unclear. We investigated the impact of nationally-endorsed acute stroke treatments on outcomes post-stroke, by aphasia status.</div></div><div><h3>Methods</h3><div>Patient-level data from the Australian Stroke Clinical Registry (2009–2013) linked to national deaths, hospital emergency presentations and admissions data were used. Aphasia was identified for the index stroke event (ICD-10 diagnosis code R47.0). Impact of receiving an optimal stroke care bundle (stroke unit care, antihypertensive medication at discharge and discharge care plan) and an acute ischemic stroke (AIS) care bundle (stroke unit care, intravenous thrombolysis and aspirin within 48 h of admission) on outcomes were analysed using multivariable regression models with propensity score adjustment.</div></div><div><h3>Results</h3><div>The study included 12,690 patients with a median age of 76, 54 % male, and 26 % with aphasia. Non-receipt of the optimal stroke care bundle was associated with worse survival, compared to optimal care, in people with aphasia (HR: 3.37; 95 % CI 2.10, 5.40; <em>p</em> < 0.05) and without aphasia (HR: 2.10; 95 % CI 1.19, 3.69; p < 0.05). Notably, the dose-response effect on survival was more pronounced in individuals with aphasia. In those who received the AIS care bundle, readmission within 12 months was greater in those without aphasia (vs aphasia, <em>p</em>-value interaction = 0.001), whereas survival was similar (p-value interaction = 0.731).</div></div><div><h3>Conclusions</h3><div>Survivors of stroke with aphasia who did not receive the optimal stroke care bundle, had worse survival at 12 months post-stroke. Ensuring eligible patients receive the optimal stroke care bundle is crucial for improving their 12-month survival.</div></div>","PeriodicalId":17417,"journal":{"name":"Journal of the Neurological Sciences","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142327149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Corrigendum to "Hemorrhagic shock and encephalopathy syndrome: A call for new clinical criteria for early intervention" [Journal of the Neurological Sciences, 465 (2024) in press (JNS 123207)]. 出血性休克和脑病综合征：呼吁制定早期干预的新临床标准"[《神经科学杂志》，465 (2024) 出版中（JNS 123207）]。

IF 3.6 3区医学

Journal of the Neurological Sciences Pub Date : 2024-09-20 DOI: 10.1016/j.jns.2024.123246

Tsuyoshi Aihara, Itaru Hayakawa, Kentaro Ide, Yuichi Abe

引用次数: 0