Ralph Huits, Michael Libman, Davidson H Hamer, Emilie Javelle
{"title":"Resurgence of chikungunya in the Indian Ocean region in 2024-2025.","authors":"Ralph Huits, Michael Libman, Davidson H Hamer, Emilie Javelle","doi":"10.1093/jtm/taaf055","DOIUrl":"10.1093/jtm/taaf055","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144512110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Charlotte Perlant, Raphaëlle Klitting, Vittoria Colizza, Katy A M Gaythorpe, Gaëlle Gabiane, Xavier de Lamballerie, Anna B Failloux, Simon Cauchemez, Paolo Bosetti
{"title":"A framework to assess the risk of yellow fever emergence.","authors":"Charlotte Perlant, Raphaëlle Klitting, Vittoria Colizza, Katy A M Gaythorpe, Gaëlle Gabiane, Xavier de Lamballerie, Anna B Failloux, Simon Cauchemez, Paolo Bosetti","doi":"10.1093/jtm/taaf081","DOIUrl":"10.1093/jtm/taaf081","url":null,"abstract":"<p><strong>Background: </strong>Yellow fever (YF) is a viral hemorrhagic fever transmitted by Aedes aegypti mosquitoes. Symptoms range from mild fever to severe complications such as jaundice and haemorrhages, which can be fatal. Martinique, a French island in the Caribbean, has remained YF-free since 1908. However, the reintroduction of A. aegypti in the 1970s, the limited scope of mandatory vaccination-currently required only for international travellers to endemic areas-and increased connectivity to YF-endemic regions heighten its vulnerability. To inform local preparedness activities, we assessed the risk of YF emergence, defined as introduction and establishment, by looking at vector competence of local native species of A. aegypti in Martinique.</p><p><strong>Methods: </strong>We developed a framework to evaluate YF emergence risk, integrating multiple contributing factors and taking Martinique as a case study. We used reported cases from 2015 to 2022 to estimate the predicted force of infection in endemic countries and map genotype presence in source countries. In addition, we analyzed flight traffic patterns from 2019 to 2022 and computed genotype-specific transmission efficiency by local mosquito populations.</p><p><strong>Results: </strong>Before 2020, Brazil represented the greatest YF introduction risk due to high passenger volumes. However, the moderate transmissibility of the South America II YF virus strain in Martinique's mosquito populations partially mitigated this risk. The COVID-19 pandemic disrupted global travel, temporarily shifting the risk landscape towards African countries such as Ivory Coast and Cameroon, where the West African strain exhibits higher transmissibility. However, this risk remained limited by the low number of travellers from these regions.</p><p><strong>Conclusions: </strong>There are growing concerns about the risk of YF introduction and emergence in non-endemic territories like Martinique. Climate change, mosquito adaptability (e.g. egg resistance to desiccation, winter diapause) and intensified global travel drive this risk. This integrative risk assessment framework supports YF emergence prevention and could be applied to other at-risk territories.</p>","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12491664/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144835496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rosalia Marrone, Marco Albonico, Agnese Comelli, Lorenzo Zammarchi, Guido Calleri, Andrea Angheben, Christian Napoli
{"title":"Access to essential drugs for neglected tropical diseases in Italy: the case of Ivermectin.","authors":"Rosalia Marrone, Marco Albonico, Agnese Comelli, Lorenzo Zammarchi, Guido Calleri, Andrea Angheben, Christian Napoli","doi":"10.1093/jtm/taaf054","DOIUrl":"10.1093/jtm/taaf054","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12491661/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144275214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Roger D Gibb, Jose M Brum, Kyle J Sloan, Adam M Pitz, Benjamin T Circello, Rowan A Grayling
{"title":"Revisiting the efficacy of bismuth subsalicylate for the prevention of traveller's diarrhoea.","authors":"Roger D Gibb, Jose M Brum, Kyle J Sloan, Adam M Pitz, Benjamin T Circello, Rowan A Grayling","doi":"10.1093/jtm/taaf076","DOIUrl":"10.1093/jtm/taaf076","url":null,"abstract":"<p><p>What can be concluded from a clinical trial that spanned 5 years yet failed to achieve target enrollment, generated flat results that contradict the existing body of knowledge and has a primary efficacy endpoint confounded by a treatment-by-COVID interaction? Could it be a false negative finding?</p>","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12491659/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144731982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jan Clerinx, Ula Maniewski, Steven Van Den Broucke, Patrick Soentjens, Liselotte Cnops, Marjan Van Esbroeck, Emmanuel Bottieau
{"title":"Acute schistosomiasis in travellers: outcomes of a short-course therapy.","authors":"Jan Clerinx, Ula Maniewski, Steven Van Den Broucke, Patrick Soentjens, Liselotte Cnops, Marjan Van Esbroeck, Emmanuel Bottieau","doi":"10.1093/jtm/taaf065","DOIUrl":"10.1093/jtm/taaf065","url":null,"abstract":"<p><strong>Background: </strong>Therapy of acute schistosomiasis in travellers currently relies on poorly consistent combinations of corticosteroids and praziquantel. In a cluster of travellers recently infected with Schistosoma mattheei × Schistosoma haematobium hybrids during a trip to South Africa in 2017, we evaluated the safety and efficacy of short methylprednisolone cycles to suppress early symptoms and of a single-day praziquantel/methylprednisolone administration at well-defined time lapses.</p><p><strong>Methods: </strong>Symptomatic patients seen during the early phase, 4 to 5 weeks (week 4-5) after infection, were given oral methylprednisolone 0.5 mg/kg once daily in one or more cycles of three consecutive days until symptoms abated. Patients were seen again at week 7-8 to be given praziquantel 40 mg/kg in two divided doses 2 hours apart, followed by a single dose of oral methylprednisolone 0.5 mg/kg 2 hours later to prevent symptom exacerbation. All patients were reevaluated for symptoms and infection at week 12-14, using serum circulating anodic antigen (CAA) as a marker of active infection.</p><p><strong>Results: </strong>A total of 34 infected individuals were longitudinally followed up. Of these, 21 patients with symptoms at presentation (week 4-5) were given methylprednisolone. Symptoms abated during the first three-day cycle in 15/21 (71%), during the second cycle in another 4/21 (19%), and during the third cycle in the remaining 2/21 (10%). All 34 participants were treated with the praziquantel/steroid combination at week 7-8; 9 (26%) had mild symptoms of short duration. Only 4 (12%) developed fever and needed 1 or 2 additional days of steroids. At week 12-14, serum CAA remained detectable in only one of the 34 participants.</p><p><strong>Conclusion: </strong>In most patients, a single three-day course of methylprednisolone was sufficient to suppress symptoms of acute schistosomiasis. Only few patients experienced short lived symptom exacerbation after taking a single-day praziquantel and methylprednisolone combination at 7-8 weeks following exposure. Infection was cleared in almost all cases 4-6 weeks later.</p>","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12491658/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144553875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Laura Pezzi, Nazli Ayhan, Justine Brulé, Guillaume André Durand, Gilda Grard, Xavier de Lamballerie, Raphaelle Klitting
{"title":"Zika virus infection in a traveller returning to France from Seychelles, 2024.","authors":"Laura Pezzi, Nazli Ayhan, Justine Brulé, Guillaume André Durand, Gilda Grard, Xavier de Lamballerie, Raphaelle Klitting","doi":"10.1093/jtm/taaf048","DOIUrl":"10.1093/jtm/taaf048","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12491663/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144174385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yves-Marie Ducrot, Nicolas Lormée, Céline Michaud, Cyril Rousseau, Antoine Bertolotti
{"title":"Soft tissue ultrasound in the diagnosis of South American cutaneous myiasis.","authors":"Yves-Marie Ducrot, Nicolas Lormée, Céline Michaud, Cyril Rousseau, Antoine Bertolotti","doi":"10.1093/jtm/taaf061","DOIUrl":"10.1093/jtm/taaf061","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144528435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Severe malaria in travellers-time to create a specific definition.","authors":"Sapha Barkati, Michael Libman, Eli Schwartz","doi":"10.1093/jtm/taaf066","DOIUrl":"10.1093/jtm/taaf066","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144642864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Herbert L DuPont, Robert Steffen, Charles D Ericsson
{"title":"Re-visiting bismuth subsalicylate for the prevention of travellers' diarrhoea.","authors":"Herbert L DuPont, Robert Steffen, Charles D Ericsson","doi":"10.1093/jtm/taaf070","DOIUrl":"10.1093/jtm/taaf070","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144753698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}