Ali Ashraf Ali Monged, Xiao Yu Liu, Gerard T Flaherty
{"title":"International travel with attention-deficit hyperactivity disorder: challenges and potential solutions.","authors":"Ali Ashraf Ali Monged, Xiao Yu Liu, Gerard T Flaherty","doi":"10.1093/jtm/taag089","DOIUrl":"https://doi.org/10.1093/jtm/taag089","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149224430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Najim Z Alshahrani, Abdulrahman M Albeshry, Zuhier Awan, Harunor Rashid
{"title":"Prevalence of respiratory viruses among pilgrims in Saudi Arabia during the Hajj 2026: a cross-sectional study.","authors":"Najim Z Alshahrani, Abdulrahman M Albeshry, Zuhier Awan, Harunor Rashid","doi":"10.1093/jtm/taag093","DOIUrl":"https://doi.org/10.1093/jtm/taag093","url":null,"abstract":"<p><strong>Background: </strong>Hajj is one of the world's largest annual mass gatherings and provides favorable conditions for respiratory virus transmission because of intense crowding and extensive international travel. Contemporary post-pandemic molecular surveillance data remain limited. This study investigated the prevalence, determinants, and characteristics of respiratory virus detections among pilgrims during the 2026 Hajj season.</p><p><strong>Methods: </strong>A cross-sectional study was conducted among adult domestic and international pilgrims over an extended peri-Hajj period (before, during and after Hajj) in the year 2026. Participants completed a structured questionnaire and provided combined nasopharyngeal and oropharyngeal swab specimens for multiplex real-time RT-PCR detection of common respiratory viruses. A subset of positive samples underwent genomic sequencing for viral subtype and variant characterization. Logistic regression was used to identify factors associated with laboratory-confirmed respiratory viral infection.</p><p><strong>Results: </strong>Among 412 enrolled pilgrims across all three phases, 58 (14.1%) tested positive for at least one respiratory virus. The prevalence of viral detection was 6.7% pre-Hajj, 16.0% during Hajj and 21.4% post-Hajj. Influenza A was the predominant virus (34.5%), followed by rhinovirus (24.1%), SARS-CoV-2 (20.7%), respiratory syncytial virus (13.8%), adenovirus (5.2%), and seasonal human coronaviruses (1.7%). Diabetes mellitus, chronic lung disease and smoking were independently associated with increased odds of respiratory virus detection. Conversely, receipt of pre-travel health advice, influenza vaccination and regular facemask use were independently associated with reduced odds of respiratory virus detection.</p><p><strong>Conclusions: </strong>Respiratory virus transmission remains an important public health concern during Hajj. Strengthening pre-travel health advice, promoting influenza vaccination, and reinforcing personal preventive measures may reduce respiratory viral transmission during Hajj and other international mass gatherings.</p>","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149224374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Paolo Bosetti, Dimie Ogoina, Antoine Gessain, Vittoria Colizza, Simon Cauchemez
{"title":"Prolonged low-level inter-human mpox transmission in Nigeria prior to the global outbreak in 2022: a mathematical modelling study.","authors":"Paolo Bosetti, Dimie Ogoina, Antoine Gessain, Vittoria Colizza, Simon Cauchemez","doi":"10.1093/jtm/taag092","DOIUrl":"https://doi.org/10.1093/jtm/taag092","url":null,"abstract":"<p><strong>Background: </strong>The 2022 global mpox outbreak was linked to clade IIb viruses that previously circulated in Nigeria. Genomic evidence suggests that, in Nigeria, sustained human-to-human transmission may have begun as early as 2016.</p><p><strong>Methods: </strong>Using a stochastic branching process model, we investigated the conditions under which mpox could have persisted at low levels in Nigeria between 2016 and April 2022 without triggering a clearly recognized outbreak and quantified the potential hidden burden of infection and international exportation.</p><p><strong>Results: </strong>We found that when R is close to 1 and secondary infections show low variability (low heterogeneity, i.e. no superspreading), sustained but slow transmission can persist with non-negligible probability. Under our baseline modelling assumptions (R = 1.0, Poisson offspring distribution), 9% of simulations resulted in cryptic epidemics that lasted throughout the study period. Conditional on a trajectory being classified as cryptic under this scenario, the average epidemic size was 8,500 infections (95% prediction interval: 2,900-17,000) per cryptic epidemic, compared with 241 confirmed cases reported. This implies substantial under ascertainment with a detection rate of 2.8% (95% prediction interval: 1.4-8.3%). Estimated exportations to Europe and North America were consistent with the small number of documented travel-associated cases before 2022.</p><p><strong>Conclusions: </strong>These findings support the plausibility of prolonged, low-level mpox transmission in Nigeria prior to the recognized global outbreak.</p>","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149224352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lucía Platero, Graciela Rodríguez-Sevilla, María Isabel Esteban-Rodríguez, Begoña Marín, Jorge Zamorano, Beatriz Díaz-Pollán, Rosa Miguel Buckley, Marta Díaz-Menéndez, Jara Llenas-García
{"title":"Neurocysticercosis as a surgical surprise: lessons from a solitary lesion mimicking primary brain neoplasm in a non-endemic setting.","authors":"Lucía Platero, Graciela Rodríguez-Sevilla, María Isabel Esteban-Rodríguez, Begoña Marín, Jorge Zamorano, Beatriz Díaz-Pollán, Rosa Miguel Buckley, Marta Díaz-Menéndez, Jara Llenas-García","doi":"10.1093/jtm/taag090","DOIUrl":"https://doi.org/10.1093/jtm/taag090","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149224384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Juliette Condé, Bénédicte Coulm, Florence Tubach, Delphine Beghin, Valérie Pourcher, Isabelle Monier, Nathalie Lelong, Julie Tort, Mathilde Latour, Catherine Vauzelle, Elisabeth Elefant, Jonathan Luke Richardson, Agnès Dechartres, Benoît Marin
{"title":"Atovaquone-proguanil chemoprophylaxis during pregnancy: a case series and a systematic review and meta-analysis.","authors":"Juliette Condé, Bénédicte Coulm, Florence Tubach, Delphine Beghin, Valérie Pourcher, Isabelle Monier, Nathalie Lelong, Julie Tort, Mathilde Latour, Catherine Vauzelle, Elisabeth Elefant, Jonathan Luke Richardson, Agnès Dechartres, Benoît Marin","doi":"10.1093/jtm/taag088","DOIUrl":"https://doi.org/10.1093/jtm/taag088","url":null,"abstract":"<p><strong>Background: </strong>Pregnant women travelling to malaria endemic areas require effective chemoprophylaxis, with limited options including atovaquone-proguanil (AP) for which safety data remain limited. Our objective was to describe the prevalences of pregnancy outcomes and major congenital anomaly (MCA) following AP chemoprophylaxis during pregnancy.</p><p><strong>Methods: </strong>We combined a case series from the French national Teratology Information Service (CRAT) and a systematic review and meta-analysis (SRMA), including prospective pregnancies exposed to AP for chemoprophylaxis. Outcomes were prevalence of pregnancy outcomes and MCA. The case series included all pregnancies referred to the CRAT with an expected date of delivery between 2009-2025, and known outcome. The SRMA searched Medline, Embase, Cochrane databases and grey literature up to 16/09/2025. Study selection and data extraction were performed using an independent dual review process. Risk of bias was assessed with ROBINS-I. Pooled prevalences were estimated using random-effects models. GRADE was used to assess certainty of evidence.</p><p><strong>Results: </strong>Our case series included 191 AP-exposed pregnancies (133 during first-trimester (T1) and 75 during second/third trimester) resulting in 85.9% livebirths (n=164), 10.0% miscarriages (n=19), 1.0% medical abortions (n=2), 1.0% stillbirth (n=2) and 2.1% elective termination (n=4). The prevalence of MCA among T1-exposed pregnancies with documented MCA status (n=110) was 3.6% (95%CI[1.0;9.0]). The SRMA included four studies, which when combined with our case series (555 AP-exposed pregnancies, 457 during T1) produced a pooled prevalence of livebirths of 80.3% (95%CI[72.3;87.2], I2=67.2%, Phet=0,047), 14.6% miscarriages (95%CI[7.3;23.9], I2=73.2%, Phet=0,024) and 2.7% for MCA (95%CI[1.2;4.8], I2=0.0%, Phet=0,45). Level of evidence was low.</p><p><strong>Conclusions: </strong>Our findings suggest that pregnancy outcomes and MCA following AP chemoprophylaxis exposure are similar to the general population prevalences, with a low level of evidence. These data strengthen the evidence supporting a reassuring safety profile, and AP may represent a reasonable option for pregnant women requiring malaria chemoprophylaxis after risk-benefit assessment.</p>","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149194891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Seif S Al-Abri, Eskild Petersen, Moses J Bockarie, John Ditekemena, Ziad A Memish
{"title":"The cycle of recurrence: why Ebola persists in an era of countermeasure abundance.","authors":"Seif S Al-Abri, Eskild Petersen, Moses J Bockarie, John Ditekemena, Ziad A Memish","doi":"10.1093/jtm/taag050","DOIUrl":"10.1093/jtm/taag050","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148271910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Isaac I Bogoch, Sapha Barkati, Marta Díaz-Menéndez, Loïc Epelboin, Daniel T Leung, Shaun K Morris, Francesca F Norman, Robert J Rolfe, Stephen D Vaughan, Kevin O'Laughlin, Michael Libman, Rinki Goswami
{"title":"Hantavirus infection in returned travellers: data from the GeoSentinel network.","authors":"Isaac I Bogoch, Sapha Barkati, Marta Díaz-Menéndez, Loïc Epelboin, Daniel T Leung, Shaun K Morris, Francesca F Norman, Robert J Rolfe, Stephen D Vaughan, Kevin O'Laughlin, Michael Libman, Rinki Goswami","doi":"10.1093/jtm/taag062","DOIUrl":"10.1093/jtm/taag062","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148391089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dengue in the high Himalayas: new challenges for travel medicine.","authors":"Alisha Gc, Gaurab Karki, Stephen Muhindi, Sandeep Thapa, Binod Rayamajhee, Binod Gc","doi":"10.1093/jtm/taag054","DOIUrl":"10.1093/jtm/taag054","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148295513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Preserving vaccination across the Pacific and beyond: the Asian route of the Royal Philanthropic Vaccine Expedition.","authors":"Jose Tuells","doi":"10.1093/jtm/taag076","DOIUrl":"10.1093/jtm/taag076","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148818801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ziad A Memish, Seif Salem Al-Abri, Shahul H Ebrahim, John Ditekemena, Dieudonné Mwamba
{"title":"The PHEIC threshold: what Ebola has that Hantavirus does not.","authors":"Ziad A Memish, Seif Salem Al-Abri, Shahul H Ebrahim, John Ditekemena, Dieudonné Mwamba","doi":"10.1093/jtm/taag058","DOIUrl":"10.1093/jtm/taag058","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2026-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148308357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}