Journal of travel medicine最新文献

{"title":"Is it time to systematically address HIV pre-exposure prophylaxis in travelers?","authors":"Izar Blazquez, Berta Torres, Alex Almuedo-Riera, Juan Ambrosioni, Daniel Camprubí-Ferrer","doi":"10.1093/jtm/taag032","DOIUrl":"https://doi.org/10.1093/jtm/taag032","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":6.4,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147839179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patterns of Antibiotic Prescription and Use for Travellers' Diarrhoea Among Travellers.","authors":"Beth Lippman, Abigail Immanuel, Kevin Dieckhaus","doi":"10.1093/jtm/taag031","DOIUrl":"https://doi.org/10.1093/jtm/taag031","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":6.4,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147839247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Re: Time requirements of pre-acclimatization at simulated altitude to prevent acute mountain sickness.","authors":"Shiyu Li, Jingyi Cao, Xiuzhe Ma, Weiyi Xu, Jiawei Wang, Ting Li","doi":"10.1093/jtm/taag029","DOIUrl":"https://doi.org/10.1093/jtm/taag029","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":6.4,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147775441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An autochthonous outbreak of Dengue in Spain in 2024.","authors":"Patricia Nadal-Barón, Mª Assumpció Bou-Monclus, Glòria Ferrús Serra, Sergio Pardo Granell, Sofia Minguell Vergés, Susana Cerdán López, Ana Bocio Sanz, Martinez Mateo Ana, Itziar Martinez Calleja, Rosa Mercè Vileu Vallverdú, Beatriz Villar Navas, Elena Garcia Bueno, Irene Corbella, Jessica Navero-Castillejos, Cristina Andrés, Andrés Antón, Carmen Chacón, Jacobo Mendioroz, Esteve Fernández Muñoz, Miguel J Martinez, Elena Sulleiro","doi":"10.1093/jtm/taag030","DOIUrl":"https://doi.org/10.1093/jtm/taag030","url":null,"abstract":"<p><strong>Background: </strong>Autochthonous dengue transmission is increasingly being reported in temperate regions of Europe, particularly in areas with established Aedes albopictus populations and high population mobility. We describe a locally acquired dengue outbreak identified in Vila-seca (Tarragona, north-eastern Spain), which involved eight confirmed cases, two of which were asymptomatic, and the associated public health response.</p><p><strong>Methods: </strong>Following the notification of two non-travel-associated dengue cases in September 2024 at Hospital Universitari de Tarragona Joan XXIII, epidemiological, virological, and entomological investigations were conducted led by Public Health Agency of Catalonia with the collaboration of microbiology departments of Vall d'Hebron Hospital Universitari and Hospital Clínic of Barcelona. Active case finding, contact tracing, laboratory confirmation, viral sequencing, and vector surveillance were implemented in the affected area of Vila-seca (Spain).</p><p><strong>Results: </strong>A total of eight confirmed dengue cases were identified. The index cases were two residents without travel history who presented with fever, rash, and myalgia and tested positive for dengue virus (DENV). Four additional cases were detected through active surveillance, including three household contacts employed at a nearby entertainment resort and one resident living approximately 160 meters from the index household. Two further epidemiologically linked cases were identified among French tourists following international alerts. All patients recovered, and no additional cases were detected after November 2024, coinciding with decreased vector activity. Virological analysis confirmed local transmission of DENV-1, genotype V (clade D.2). Entomological surveys demonstrated widespread Ae. albopictus presence in public and private settings, prompting immediate vector control interventions, although no infected mosquitoes were detected.</p><p><strong>Conclusions: </strong>This outbreak illustrates the growing risk of DENV transmission in non-endemic European settings with intense tourist and occupational mobility. Rapid diagnostics, genomic surveillance, coordinated vector control, and timely international communication are essential to limit transmission and protect both residents and travellers, reinforcing the importance of a One Health approach.</p>","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":6.4,"publicationDate":"2026-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147729167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rapid whole genome sequencing of Plasmodium DNA from cryptic malaria cases in UK travellers provides insights into infection origins, transmission, and antimalarial resistance.","authors":"Mark K I Tan, Nina Billows, Debbie Nolder, Sophie Moss, Jody E Phelan, Joseph Thorpe, Jonathan L Edgeworth, Colin J Sutherland, Peter L Chiodini, Susana Campino, Taane G Clark","doi":"10.1093/jtm/taag028","DOIUrl":"https://doi.org/10.1093/jtm/taag028","url":null,"abstract":"<p><strong>Background: </strong>The UK reports approximately 2,000 imported malaria cases annually, necessitating effective surveillance to determine infection sources, transmission routes, inform strategies for prevention, and detect molecular markers of drug resistance that may compromise treatment outcomes. Defined by their unclear route of infection, cryptic malaria cases pose a particular challenge for malaria surveillance because they may signify undetected localised transmission or malaria re-introduction and therefore necessitate additional public health resources and epidemiological investigations. Here, we demonstrate the utility of near-real-time whole-genome sequencing (WGS) in providing high genomic resolution and detailed molecular characterisation to help resolve cryptic malaria cases in the UK.</p><p><strong>Methods: </strong>Plasmodium DNA (9 isolates) sourced from clinical blood samples underwent WGS using either Illumina or Oxford Nanopore Technologies (ONT) platforms. Sequence data were rapidly analysed with Malaria-Profiler, which performs read mapping, variant calling, quality control, drug resistance prediction, and AI-based geographic origin inference using a reference database of more than 15,000 isolate genomes. Plasmodium ovale spp. and P. falciparum infections identified among family members were further analysed to assess parasite relatedness using identity-by-descent and multiplicity of infection approaches to investigate transmission clusters.</p><p><strong>Results: </strong>Using a combination of Illumina and ONT WGS platforms alongside Malaria-Profiler, we rapidly profiled parasites from four cryptic P. falciparum malaria cases in the UK, identifying drug resistance markers and predicting geographic origins through AI-based methods. We also applied WGS to family-related clusters of P. ovale spp and P. falciparum cases, confirming (sub)species identities and enabling fine-scale transmission cluster analysis.</p><p><strong>Conclusion: </strong>This study highlights the power of real-time WGS and AI-enhanced tools for high-resolution malaria genomic surveillance. By enabling rapid characterisation of cryptic and imported cases, this approach supports timely public health responses, including targeted epidemiological investigations and, where appropriate, the de-escalation of entomological surveillance. In doing so, it helps sustain malaria elimination in non-endemic settings.</p>","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":6.4,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147690807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Travel health needs and experiences of people living with Parkinson's Disease and their carers: An exploratory qualitative study.","authors":"Richard T Ngomba, Ian Heslop, Natasha Dsouza, Richard A Powell, Nicola Modugno, Keivan Armani","doi":"10.1093/jtm/taag027","DOIUrl":"https://doi.org/10.1093/jtm/taag027","url":null,"abstract":"<p><strong>Background: </strong>Travel is an important contributor to quality of life, independence and social participation. For people living with Parkinson's disease (PD), however, travel can pose unique health and logistical challenges. Despite the increasing emphasis on health-related quality of life in PD management, little is known about the travel needs of people living with PD. This study explored the travel experiences, needs, attitudes and practises of people living with PD, with the aim of informing future research, practice and guidance.</p><p><strong>Methods: </strong>A qualitative study using the focus group methodology was conducted with 20 participants: 10 people living with PD and 10 carers. Data were analysed using a thematic content analysis.</p><p><strong>Results: </strong>Four overarching main themes were identified: 1, Changing travel patterns; 2, Anxiety and stress of planning; 3, Travel challenges and adaptations, and 4, Addressing PD information gaps.</p><p><strong>Conclusion: </strong>Travel presents challenges for people living with PD and their carers. This study highlights the complexity of these travel-related health needs and the need for a multi-disciplinary and personalized approach. The implementation of dedicated information resources, training of operators and the promotion of support networks are fundamental steps to improving the autonomy and wellbeing of patients and their partners/carers during travel.</p>","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":6.4,"publicationDate":"2026-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147674619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Border measures may delay but rarely prevent early dominance of local transmission: imported-to-local patterns across PHEICs.","authors":"Kai Qi Lim, Ming Xuan Loy, Zeenathnisa Mougammadou Aribou, Shen Liang, Paul Anantharajah Tambyah","doi":"10.1093/jtm/taag026","DOIUrl":"https://doi.org/10.1093/jtm/taag026","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":6.4,"publicationDate":"2026-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147662748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oropouche Virus RNA Persistence and Antibody Kinetics: A Multi-Specimen, Genomic, and Serological Analysis.","authors":"Jessica Navero Castillejos, Daniel Camprubí-Ferrer, Ricard Isanta, Natalia Rodríguez, David García, Alba Antequera, Aida Peiró-Mestres, Lucia Soler, Raul Ruiz, Alexander Navarro, Adán Fernández, Marta Gracia, Mireia Pujada, Patricia Rodríguez, Miguel J Martínez, Beatriz Escudero-Pérez","doi":"10.1093/jtm/taag023","DOIUrl":"https://doi.org/10.1093/jtm/taag023","url":null,"abstract":"<p><strong>Background: </strong>Oropouche virus (OROV) is an emerging orthobunyavirus causing febrile illness in South America, yet data on viral kinetics, diagnostic samples, and serological responses remain limited.</p><p><strong>Aim: </strong>We performed a comprehensive longitudinal analysis of OROV RNA detection, antibody responses, and viral genomics in a returned traveller from Brazil to better characterize infection dynamics and inform diagnostic strategies.</p><p><strong>Methods: </strong>Multiple clinical specimens, including serum, plasma, whole blood, coagulated blood, urine, saliva, and a vaginal swab, were collected from day 3 to day 126 post-symptom onset (p.s.o.) and tested using RT-PCR and OROV-specific IgM/IgG ELISA. Near-complete viral genome sequencing (99.6% coverage) enabled genotyping and phylogenetic analysis.</p><p><strong>Results: </strong>OROV RNA exhibited compartmental specificity. Whole blood showed prolonged and stable RNA detection for over 120 days p.s.o., representing one of the longest documented periods of OROV RNA persistence to date. Coagulated blood also remained positive at multiple time points, whereas serum and plasma demonstrated only short-term detectability. Urine showed detectable viral RNA from day 4 to day 30. Saliva tested positive at day 7 p.s.o., while the vaginal swab was negative. Serologically, IgM peaked early and waned by day 79, whereas IgG remained detectable through day 126. In addition, sequencing confirmed infection with an American-lineage virus carrying reassorted genome segments clustering with Brazilian strains from 2024.</p><p><strong>Conclusion: </strong>This case provides a detailed view of OROV infection kinetics in multiple compartments, demonstrating prolonged whole-blood RNA persistence, and complete genomic characterization. These findings have direct implications for diagnostics, surveillance, and understanding OROV pathogenesis, particularly in returned travellers and settings with co-circulating arboviruses.</p>","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":6.4,"publicationDate":"2026-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147662756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Annular Erythema of the Hands Revealing Secondary Syphilis.","authors":"Lang Rao, Er-Yi Lin, Yan-Yan Feng","doi":"10.1093/jtm/taag024","DOIUrl":"https://doi.org/10.1093/jtm/taag024","url":null,"abstract":"<p><p>A secondary syphilis case presenting with an annular, copper-colored erythema on the palms. Diagnosis was confirmed by direct fluorescent antibody staining and serology. This case underscores the importance of maintaining a high level of clinical suspicion and the need for consistent condom use, particularly among high-risk populations like men who have sex with men.</p>","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":6.4,"publicationDate":"2026-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147618821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Public Health Preparedness and Infectious Disease Risk Management Across Religious Mass Gatherings: A Comparative Analysis of Hajj, Umrah, Arba'een and Kumbh Mela.","authors":"Jaffar A Al-Tawfiq, Harunor Rashid, Salim Parker, Ziad A Memish","doi":"10.1093/jtm/taag025","DOIUrl":"https://doi.org/10.1093/jtm/taag025","url":null,"abstract":"<p><strong>Background: </strong>Religious mass gatherings (MGs) such as Hajj, Umrah, Arba'een, and Kumbh Mela attract tens to hundreds of millions of participants annually, posing unique challenges for infectious disease control, surveillance, and health system preparedness.</p><p><strong>Methods: </strong>We conducted a structured comparative analysis of these four MGs, evaluating attendance scale, participant demographics, governance structures, epidemiological risks, and public health response strategies. Data were synthesized from international public health reports, peer-reviewed literature, and national MG health policies.</p><p><strong>Results: </strong>Hajj attracts 1.8-3 million pilgrims annually from >180 countries, while Umrah draws ~30 million yearly with similar global diversity. Arba'een hosts 20-22 million participants mainly from Iraq, Iran, and neighboring nations. Kumbh Mela peaks at tens of millions overall, exceeding 50 million on high days, predominantly Indian nationals plus international visitors. Common threats across these mass gatherings include respiratory pathogens, water- and food-borne illnesses, and vaccine-preventable diseases, amplified by crowding and diverse origins. Successful public health responses emphasize pre-event vaccination (e.g., meningococcal ACWY for Saudi MGs), real-time surveillance systems, and multisectoral coordination among stakeholders.</p><p><strong>Conclusions: </strong>Comparable yet distinct, these MGs require tailored risk-based frameworks emphasizing leadership, surveillance, prevention, and surge capacity. Our analysis proposes a unified model to strengthen global MG policies and practices, enhancing health security for future events.</p>","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":6.4,"publicationDate":"2026-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147618781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}