Journal of travel medicine最新文献

{"title":"Chikungunya virus in Guangdong, China in 2025.","authors":"Jiayi Wang, Leiliang Zhang","doi":"10.1093/jtm/taaf105","DOIUrl":"https://doi.org/10.1093/jtm/taaf105","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145274933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is a second dose of yellow fever vaccine needed? A systematic review of humoral and cell-mediated immunity after revaccination.","authors":"Pietro Ferrara, Adriano La Vecchia, Lorenzo Losa, Lorenzo G Mantovani, Montserrat Plana, Fernando Agüero","doi":"10.1093/jtm/taaf106","DOIUrl":"https://doi.org/10.1093/jtm/taaf106","url":null,"abstract":"<p><strong>Background: </strong>In the context of ongoing debate about whether a single dose of the yellow fever (YF) vaccine provides lifelong protection, addressing key unanswered questions-such as the extent to which revaccination enhances humoral and cell-mediated immune (CMI) responses, and the true duration of immunity-is particularly important for protecting high-risk groups. This systematic review evaluated the immunogenicity of YF revaccination, to support evidence-based vaccination policies.</p><p><strong>Methods: </strong>A systematic search in electronic databases was conducted to identify relevant studies that evaluated humoral or CMI responses following booster YF vaccination in both adults and children from endemic and non-endemic regions. Interventions included full-dose and fractional-dose YF vaccine boosters.</p><p><strong>Results: </strong>Twenty-one studies (n = 1821 participants) were included. Revaccination temporarily enhances neutralizing antibody titres, particularly in individuals with low or undetectable baseline immunity. Long-term seropositivity remained high in most cohorts. Individuals with high baseline titres showed limited humoral response, suggesting a limited boosting effect. In terms of CMI, booster generally results in minimal activation of T-cell markers compared to primary vaccination, suggesting that revaccination primarily sustains memory responses rather than inducing new activation. In individuals with low baseline immunity, it restores both T-cell and B-cell functional memories. Memory T-cell subsets remain detectable for over 10 years. Children vaccinated at ≤ 2 years and immunocompromised individuals showed marked benefits from revaccination.</p><p><strong>Conclusions: </strong>Routine YF revaccination appears unnecessary for most immunocompetent individuals across different age groups given durable protection conferred by a single dose. However, booster doses may benefit specific high-risk groups such as individuals vaccinated at very young ages, those with low baseline immunity or with altered immunocompetence.</p>","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145274965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Delayed Diagnosis and Severe Outcomes in Imported Malaria in Vietnam Highlighting Systematic Gaps in Detection.","authors":"Nguyen Thi Thu Trang, Do Duy Cuong, Nguyen Thi Huong Binh, Pham Thi Thao Huong, Nong Minh Vuong, Vu Van Giap, Doan Thu Tra","doi":"10.1093/jtm/taaf107","DOIUrl":"https://doi.org/10.1093/jtm/taaf107","url":null,"abstract":"<p><p>Analysis of 13 imported malaria cases revealed 87.5% diagnostic failure rate at primary care facilities, with 38.5% progressing to severe malaria, emphasizing critical gaps in Vietnam's malaria elimination strategy.</p>","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145274926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"\"Cabo Verde: Is It Really Malaria-Free?\"","authors":"Raquel Diogo, Bruno Tiago Carvalho, Luísa Mendonça, Maria Ribeiro Cunha, Diogo Mendes Pedro, Filipa Paramés, Tiago Marques, Sérgio Eduardo Paulo, J Melo Cristino, Álvaro Ayres Pereira","doi":"10.1093/jtm/taaf108","DOIUrl":"https://doi.org/10.1093/jtm/taaf108","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145274951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Viable Schistosoma mansoni infection 41 years after last exposure - a case report of a loyal parasite.","authors":"Cornelia Staehelin, Anna Eichenberger, Aart Mookhoek, Robert Hoepner, Claudia Münger, Nadine Sidler, Linda J Wammes, Beatrice Nickel, Maura Concu, Andreas Neumayr, Alexander Oberli","doi":"10.1093/jtm/taaf103","DOIUrl":"https://doi.org/10.1093/jtm/taaf103","url":null,"abstract":"<p><p>Schistosoma species may show extraordinary longevity, despite not replicating in human hosts. We present a case of active S. mansoni infection in a Swiss patient 41 years after her one and only possible exposure (swimming in Lake Kivu, Rwanda).</p>","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145251781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Descriptive analysis of GeoSentinel publication altmetrics data.","authors":"Gerard T Flaherty, Dhanvin Raj Puppala, Bingling Chen, Davidson H Hamer","doi":"10.1093/jtm/taaf102","DOIUrl":"https://doi.org/10.1093/jtm/taaf102","url":null,"abstract":"<p><p>This study examined the public online attention received by GeoSentinel articles as a measure of their societal and public health impact and found that most articles featured in social media posts. Articles that were picked up by influential organisations such as the WHO or CDC tended to have a specific communicable disease focus.</p>","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145251785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dirofilariasis presenting with recurrent solitary erythematous swellings and creeping dermatitis.","authors":"Sofya Lukovnikova, Celia Degonda, Bernhard Beck, Maura Concu, Beatrice Nickel, Andreas Neumayr","doi":"10.1093/jtm/taaf100","DOIUrl":"https://doi.org/10.1093/jtm/taaf100","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145206798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Loiasis presenting as monolateral cervical lymphadenopathy.","authors":"Bianca M Longo, Paolo Bigliano, Valentina Libanore, Silvia Fontana, Fabio A Ranzani, Francesco Cabutti, Daniele Ricci, Elda Feyles, Salvatore Scarso, Andrea Angheben, Maria T Brusa, Federico Gobbi, Andrea Calcagno","doi":"10.1093/jtm/taaf086","DOIUrl":"10.1093/jtm/taaf086","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144958922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognosis of isolated hyperparasitemia in adults with imported severe malaria.","authors":"Sébastien Gaultier, Sandrine Houzé, Marc Thellier, Michael Thy, Nathan Peiffer-Smadja, Hermann Do Rego, Stéphane Jauréguiberry, Jean-François Timsit, Etienne de Montmollin","doi":"10.1093/jtm/taaf042","DOIUrl":"10.1093/jtm/taaf042","url":null,"abstract":"<p><strong>Background: </strong>Hyperparasitemia (HP), defined as a parasitemia > 4%, is the most frequent severity criterion considered in adults with imported malaria. Isolated hyperparasitemia (iHP), accounting for 10-40% of cases, has a controversial prognostic significance.</p><p><strong>Methods: </strong>Multicenter retrospective study including all adult patients with imported Plasmodium falciparum malaria and HP admitted to 16 hospitals in the Greater Paris area between 2018 and 2022 and reported to the National Reference Center. Amongst HP patients, iHP at hospital admission was identified by retrospective analysis of medical records to minimize classification bias. The primary endpoint was a composite outcome using the Desirability of Outcome Ranking (DOOR) method with three levels of decreasing desirability: hospital survival, absence of organ support requirement, shortest length of stay. Association between HP, iHP and outcomes was evaluated by negative binomial regression models.</p><p><strong>Results: </strong>Of 355 patients enrolled with HP, 135 (38%) had iHP. iHP patients were predominantly male (55.6%), aged 41 (32-52.3) years and born in an endemic country (86.4%). Compared with patients with HP and additional severity criteria, iHP was independently associated with a lower risk of worse DOOR [RR 0.56, 95%CI (0.48-0.65)]. No deaths were recorded in the iHP population, and 2/135 (1.5%) patients required organ support. In the iHP population, immunosuppression [RR 1.65, 95%CI (1.16-2.37)] and parasitemia>10% [RR 1.57, 95%CI (1.01-2.24)] were independently associated with worse DOOR. Only 47 (34.8%) iHP patients were admitted to an ICU at diagnosis, and 40 (29.6%) were treated with oral therapy alone.</p><p><strong>Conclusion: </strong>In imported malaria in France, iHP was associated with a low risk of serious adverse outcomes overall. In patients with iHP, immunosuppression and parasitemia >10% were associated with an increased risk of adverse outcome, highlighting the importance of a close hospital monitoring.</p>","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144142527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Severe imported Plasmodium falciparum malaria with hyperparasitaemia: evaluation of determinants of critical disease in adult returning travellers.","authors":"Tilman Lingscheid, Johannes Jochum, Pinkus Tober-Lau, Johanna Schöllgen, Regina Stegherr, Juliane Dörfler, Henrik Nielsen, Alessandro Bartoloni, Kristine Mørch, Emmanuel Bottieau, Frieder Pfäfflin, Leif Erik Sander, Thomas Zoller, Michael Ramharter, Florian Kurth","doi":"10.1093/jtm/taaf049","DOIUrl":"10.1093/jtm/taaf049","url":null,"abstract":"<p><strong>Background: </strong>Severe Plasmodium falciparum (P.f.) malaria remains a major health threat for travellers. World Health Organization (WHO) defines criteria for severe malaria, including hyperparasitaemia ≥10% infected red blood cells (iRBCs), as major risk factors for adverse outcome. Additionally, WHO recognizes 'uncomplicated hyperparasitaemia' with 4-10% iRBC, a parasite density usually defining severe malaria outside endemic areas. Overall, the role of hyperparasitaemia as an independent risk factor in imported severe malaria is unclear, with most data predating the artemisinin era.</p><p><strong>Methods: </strong>We retrospectively analysed adult in-patients with hyperparasitaemia (≥4% iRBC) and/or severe P.f. malaria according to WHO criteria who received artemisinin-based treatment at two German university hospitals 2013-2023, to assess the risk for critical disease with need for organ replacement therapy or vasopressors. Based on multivariable nominal logistic regression, we developed a scoring system to identify patients with critical disease and validated it on an independent cohort.</p><p><strong>Results: </strong>Of 168 patients, 33 (20%) developed critical disease, all of whom presented with at least one WHO criterion other than hyperparasitaemia. Of 72 patients with isolated hyperparasitaemia, none developed critical disease. Hyperparasitaemia was no independent risk factor for critical disease in logistic regression (adjusted odds ratio (aOR) 0.85 95%CI 0.23-3.12), in contrast to creatinine >3 mg/dl (aOR 6.74 95%CI 1.06-42.75), oligo-/anuria (aOR 5.94 95%CI 1.27-27.82), lactate ≥5 mmol/l (aOR 8.16 95%CI 8.16-35.03), confusion (aOR 4.07 95%CI 1.39-11.94) and circulatory shock and respiratory failure, which are inherently critical conditions. The risk score identified all 33 patients with and 131/135 (97.0%) without critical disease (AUC = 0.99; sensitivity: 100%; specificity: 97.0%). In the validation cohort, all eight patients with critical disease and 39/44 (89%) without were correctly identified.</p><p><strong>Conclusion: </strong>Isolated hyperparasitaemia was no independent risk factor for critical disease in this patient cohort treated with artemisinins, suggesting that such patients can be managed outside intensive care units.</p>","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144187282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}