Sarah L McGuinness, Stephen Muhi, Maya L Nadimpalli, Ahmed Babiker, Caroline Theunissen, Giacomo Stroffolini, Leonardo Motta, Federico Gobbi, Ralph Huits, Michael Libman, Karin Leder
{"title":"Patient characteristics and antimicrobial susceptibility profiles of Escherichia coli and Klebsiella pneumoniae infections in international travellers: a GeoSentinel analysis.","authors":"Sarah L McGuinness, Stephen Muhi, Maya L Nadimpalli, Ahmed Babiker, Caroline Theunissen, Giacomo Stroffolini, Leonardo Motta, Federico Gobbi, Ralph Huits, Michael Libman, Karin Leder","doi":"10.1093/jtm/taae090","DOIUrl":"https://doi.org/10.1093/jtm/taae090","url":null,"abstract":"<p><strong>Background: </strong>Antimicrobial resistance (AMR) is a global health crisis, with Enterobacterales including Escherichia coli and Klebsiella pneumoniae playing significant roles. While international travel to low- and middle-income countries is linked to colonisation with AMR Enterobacterales, the clinical implications, particularly the risk of subsequent infection, remain unclear due to limited data. We aimed to characterise E. coli and K. pneumoniae infections in travellers and the antimicrobial susceptibility profiles of their isolates.</p><p><strong>Methods: </strong>We analysed data on E. coli and K. pneumoniae infections in travellers collected at GeoSentinel sites between 2015 and 2022, focusing on epidemiological, clinical and microbiological characteristics. We defined multi-drug resistance (MDR) as non-susceptibility to agents from at least three drug classes.</p><p><strong>Results: </strong>Over the 8-year period, we included 655 patients (median age 41 years; 74% female) from 57 sites in 27 countries, with 584 E. coli and 72 K. pneumoniae infections. Common travel regions included Sub-Saharan Africa, Southeast Asia, and South-Central Asia. Urinary tract infections predominated. Almost half (45%) were hospitalised. Among infections with antimicrobial susceptibility data across three or more drug classes, 203/544 (37%) E. coli and 19/67 (28%) K. pneumoniae demonstrated MDR. Over one-third of E. coli and K. pneumoniae isolates were non-susceptible to third-generation cephalosporins and cotrimoxazole, with 38% and 28% non-susceptible to fluoroquinolones, respectively. Travellers to South-Central Asia most frequently had isolates non-susceptible to third-generation cephalosporins, fluoroquinolones and carbapenems. We observed increasing frequencies of phenotypic extended spectrum beta-lactamase and carbapenem resistance over time.</p><p><strong>Conclusions: </strong>E. coli and K. pneumoniae infections in travellers, particularly those to Asia, may be challenging to empirically treat. Our analysis highlights the significant health risks these infections pose to travellers and emphasises the escalating global threat of AMR. Enhanced, systematic AMR surveillance in travellers is needed, along with prospective data on infection risk post travel-related AMR organism acquisition.</p>","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":null,"pages":null},"PeriodicalIF":9.1,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141476863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Caterina Davoli, Pietro Sponga, Andrea Angheben, Federico G Gobbi
{"title":"Post-malaria delayed cerebellar ataxia in a traveller.","authors":"Caterina Davoli, Pietro Sponga, Andrea Angheben, Federico G Gobbi","doi":"10.1093/jtm/taae083","DOIUrl":"https://doi.org/10.1093/jtm/taae083","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":null,"pages":null},"PeriodicalIF":9.1,"publicationDate":"2024-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141469043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on imported malaria associated with international travel in China.","authors":"Jianhai Yin","doi":"10.1093/jtm/taae078","DOIUrl":"https://doi.org/10.1093/jtm/taae078","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":null,"pages":null},"PeriodicalIF":25.7,"publicationDate":"2024-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141284023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wondimeneh Shiferaw, Judith A Dean, Deborah Mills, Colleen Lau, Luis Furuya-Kanamori
{"title":"Definition and classification of 'travellers' in research: a bibliometric analysis.","authors":"Wondimeneh Shiferaw, Judith A Dean, Deborah Mills, Colleen Lau, Luis Furuya-Kanamori","doi":"10.1093/jtm/taae048","DOIUrl":"10.1093/jtm/taae048","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":null,"pages":null},"PeriodicalIF":25.7,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11149717/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140158426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dhammika Leshan Wannigama, Mohan Amarasiri, Phatthranit Phattharapornjaroen, Cameron Hurst, Charin Modchang, Sudarat Chadsuthi, Suparinthon Anupong, Kazuhiko Miyanaga, Longzhu Cui, W K C P Werawatte, S M Ali Hosseini Rad, Stefan Fernandez, Angkana T Huang, Porames Vatanaprasan, Thammakorn Saethang, Sirirat Luk-In, Robin James Storer, Puey Ounjai, Ratana Tacharoenmuang, Naveen Kumar Devanga Ragupathi, Phitsanuruk Kanthawee, Bernadina Cynthia, John Jefferson V Besa, Asada Leelahavanichkul, Talerngsak Kanjanabuch, Paul G Higgins, Asuka Nanbo, Anthony Kicic, Andrew C Singer, Tanittha Chatsuwan, Sam Trowsdale, Takashi Furukawa, Kazunari Sei, Daisuke Sano, Hitoshi Ishikawa, Kenji Shibuya, Aisha Khatib, Shuichi Abe, Parichart Hongsing
{"title":"Wastewater-based epidemiological surveillance of SARS-CoV-2 new variants BA.2.86 and offspring JN.1 in South and Southeast Asia.","authors":"Dhammika Leshan Wannigama, Mohan Amarasiri, Phatthranit Phattharapornjaroen, Cameron Hurst, Charin Modchang, Sudarat Chadsuthi, Suparinthon Anupong, Kazuhiko Miyanaga, Longzhu Cui, W K C P Werawatte, S M Ali Hosseini Rad, Stefan Fernandez, Angkana T Huang, Porames Vatanaprasan, Thammakorn Saethang, Sirirat Luk-In, Robin James Storer, Puey Ounjai, Ratana Tacharoenmuang, Naveen Kumar Devanga Ragupathi, Phitsanuruk Kanthawee, Bernadina Cynthia, John Jefferson V Besa, Asada Leelahavanichkul, Talerngsak Kanjanabuch, Paul G Higgins, Asuka Nanbo, Anthony Kicic, Andrew C Singer, Tanittha Chatsuwan, Sam Trowsdale, Takashi Furukawa, Kazunari Sei, Daisuke Sano, Hitoshi Ishikawa, Kenji Shibuya, Aisha Khatib, Shuichi Abe, Parichart Hongsing","doi":"10.1093/jtm/taae040","DOIUrl":"10.1093/jtm/taae040","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":null,"pages":null},"PeriodicalIF":25.7,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140028289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ursula Benz, Mohamad M Traore, Edita E Revay, Amadou S Traore, Alexey M Prozorov, Issa Traoré, Amy Junnila, Liwang Cui, Aidas Saldaitis, Aboubakr S Kone, Roman V Yakovlev, Younoussa Ziguime, Petrányi Gergely, Siriman Samake, Alou Keita, Günter C Müller, Thomas Weitzel, Camilla Rothe
{"title":"Effect of textile colour on vector mosquito host selection: a simulated field study in Mali, West Africa.","authors":"Ursula Benz, Mohamad M Traore, Edita E Revay, Amadou S Traore, Alexey M Prozorov, Issa Traoré, Amy Junnila, Liwang Cui, Aidas Saldaitis, Aboubakr S Kone, Roman V Yakovlev, Younoussa Ziguime, Petrányi Gergely, Siriman Samake, Alou Keita, Günter C Müller, Thomas Weitzel, Camilla Rothe","doi":"10.1093/jtm/taae049","DOIUrl":"10.1093/jtm/taae049","url":null,"abstract":"<p><strong>Background: </strong>The effect of clothing colour on the biting rates of different vector mosquito species is not well understood. Studies under tropical field conditions are lacking. This study aimed to determine the influence of clothing colours on mosquito biting rates in rural and suburban settings in West Africa.</p><p><strong>Methods: </strong>We performed a simulated field study in a suburban and a rural site in Mali using Mosquito-Magnet traps utilizing CO2 and other attractants, which were covered with black, white, and black/white striped textile sheets covers. These targets operated continuously for 10 consecutive days with bright nights (around full moon) and 10 consecutive days with dark nights (around new moon). Trapped mosquitoes were collected and catch rates counted hourly. Mosquitoes were morphologically identified to the species complex level (Anopheles gambiae s.l. and Culex pipiens s.l.) or species level (Aedes aegypti). A subset of Anopheles specimens were further identified by molecular methods.</p><p><strong>Results: </strong>Under bright-night conditions, An. gambiae s.l. was significantly more attracted to black targets than to white and striped targets; during dark nights, no target preference was noted. During bright nights, Cx. pipiens s.l. was significantly more attracted to black and striped targets than to white targets; a similar trend was noted during dark nights (not significant). For day-active Ae. aegypti, striped targets were more attractive than the other targets and black were more attractive than white targets.</p><p><strong>Conclusions: </strong>The study firstly demonstrated that under field conditions in Mali, West Africa, mosquito catch rates were influenced by different clothing colours, depending on mosquito species and light conditions. Overall, light colours were least attractive to host-seeking mosquitoes. Using white or other light-coloured clothing can potentially reduce bite exposure and risk of disease transmission in endemic tropical regions.</p>","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":null,"pages":null},"PeriodicalIF":25.7,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140158427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Carlos Santaolaya, Juhi Malhotra, James A Fowler, Sarah Warzywoda, Joe Debattista, Deborah J Mills, Colleen Lau, Luis Furuya-Kanamori, Jo Durham, Amy B Mullens, Satrio N Istiko, Judith A Dean
{"title":"Integrating sexual and reproductive health into pre-travel consultations.","authors":"Carlos Santaolaya, Juhi Malhotra, James A Fowler, Sarah Warzywoda, Joe Debattista, Deborah J Mills, Colleen Lau, Luis Furuya-Kanamori, Jo Durham, Amy B Mullens, Satrio N Istiko, Judith A Dean","doi":"10.1093/jtm/taae024","DOIUrl":"10.1093/jtm/taae024","url":null,"abstract":"<p><strong>Background: </strong>Casual sex during travel is a major preventable factor in the global transmission of sexually transmissible infections (STI). Pre-travel consults present an excellent opportunity for practitioners to educate travellers about sexual and reproductive health (SRH) and safety. This scoping review aims to explore and understand the extent to which SRH is included in pre-travel consultations.</p><p><strong>Methods: </strong>PubMed, Embase, Cumulative Index to Nursing and Allied Health Literature, Scopus, Medline and Web of Science were systematically searched for primary research articles exploring whether health care practitioners (HCP) included SRH in pre-travel consultations. Extracted findings were synthesized and presented in narrative form.</p><p><strong>Results: </strong>Findings across 13 articles suggest HCPs infrequently broached SRH in pre-travel consultations with HCP discomfort, and lack of time and resources presented as key barriers. Urban practice settings, HCP experience, training in travel medicine and traveller characteristics such as sexual orientation were positively associated with discussions about SRH. SRH advice reported was general in nature, primarily focusing on safer sex, condoms or unspecified STI advice. Risk assessments based solely on age or stereotypes around sexual preferences led to key aspects of SRH care being missed for some (e.g. SRH was less likely to be discussed with older travellers).</p><p><strong>Conclusions: </strong>HCPs frequently miss opportunities to integrate SRH into pre-travel consultations. Strategies to promote HCP confidence and awareness present a promising means to boost the frequency and quality of SRH advice disseminated. Integrating culturally safe and responsive SRH history-taking and advice into pre-travel consultations may contribute to global reductions in STI transmission and promote traveller SRH well-being.</p>","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":null,"pages":null},"PeriodicalIF":9.1,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11149722/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139716115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wondimeneh Shiferaw, Beatris Mario Martin, Judith A Dean, Deborah Mills, Colleen Lau, David Paterson, Kenneth Koh, Lars Eriksson, Luis Furuya-Kanamori
{"title":"A systematic review and meta-analysis of sexually transmitted infections and blood-borne viruses in travellers.","authors":"Wondimeneh Shiferaw, Beatris Mario Martin, Judith A Dean, Deborah Mills, Colleen Lau, David Paterson, Kenneth Koh, Lars Eriksson, Luis Furuya-Kanamori","doi":"10.1093/jtm/taae038","DOIUrl":"10.1093/jtm/taae038","url":null,"abstract":"<p><strong>Background: </strong>Sexually transmitted infections (STIs) and blood-borne viruses (BBVs) impose a global health and economic burden. International travellers facilitate the spread of infectious diseases, including STIs. Hence, this review assessed the prevalence/proportionate morbidity of travellers with STIs and sexually transmitted BBVs and factors associated with the infection in this population.</p><p><strong>Methods: </strong>PubMed, Scopus, Web of Science, Cumulative Index to Nursing and Allied Health Literature (CINAHL), Embase and Cochrane Library were searched from inception of the databases until November 2022. Published analytical observational studies reporting the prevalence/proportionate morbidity of travellers with STIs and factors associated with STIs by type of traveller [i.e. tourists, business travellers, students, visiting friends or relatives (VFRs), international truck drivers, backpackers, expatriates and men who have sex with men (MSM)] were included. The selection of articles, data extraction and risk of bias assessment were conducted by two independent reviewers. Meta-analyses were conducted for each STI by clinical presentation and type of traveller.</p><p><strong>Results: </strong>Thirty-two studies (n = 387 731 travellers) were included; 19 evaluated the proportionate morbidity of STIs among symptomatic travellers, while 13 examined the prevalence of STIs in asymptomatic travellers. The highest proportionate morbidity was found among VFRs (syphilis, 1.67%; 95% CI: 1.03-2.81%), backpackers (Chlamydia trachomatis, 6.58%; 95% CI: 5.96-7.25%) and MSM (HIV [2.50%;95% CI: 0.44-12.88%], gonorrhoea [4.17%; 95% CI: 1.1.5-13.98%], lymphogranuloma venereum [4.17%;95% CI: 1.1.5-13.98%] and HAV [20.0%; 95% CI: 14.99-26.17%]). The highest prevalence of STIs among asymptomatic were found in MSM (HIV [25.94%; 95% CI: 22.21-30.05%] and HBV [24.90%; 95% CI: 21.23-28.96%]) and backpackers (C. trachomatis, 3.92%; 95% CI: 2.72-5.32%). Short duration of the trip (<1 month), not having pre-travel consultation, travelling to Southeast Asia and being unvaccinated for HBV were identified as risk factors for STIs.</p><p><strong>Conclusion: </strong>Strategies to prevent STIs and sexually transmitted BBVs should be discussed at pre-travel consultations, and recommendations should be prioritized in high-risk groups of travellers, such as backpackers, VFRs and MSMs. Additionally, healthcare providers should tailor recommendations for safe sex practices to individual travellers' unique needs.</p>","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":null,"pages":null},"PeriodicalIF":9.1,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11149723/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140028284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Visa Relaxation Policies and Potential Implications on Public Health in Africa.","authors":"Allan Komakech, Karl Angendu Baki, Jonathan Izudi","doi":"10.1093/jtm/taae032","DOIUrl":"10.1093/jtm/taae032","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":null,"pages":null},"PeriodicalIF":25.7,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139931754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cyclones and flooding in tropical Northern Australia increase the risk of exposure to melioidosis.","authors":"Irmgard L Bauer","doi":"10.1093/jtm/taae031","DOIUrl":"10.1093/jtm/taae031","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":null,"pages":null},"PeriodicalIF":25.7,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139746826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}