{"title":"Patterns of Antibiotic Prescription and Use for Travellers' Diarrhoea Among Travellers.","authors":"Beth Lippman, Abigail Immanuel, Kevin Dieckhaus","doi":"10.1093/jtm/taag031","DOIUrl":"https://doi.org/10.1093/jtm/taag031","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":6.4,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147839247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dissemination and outcome reporting bias in clinical rabies trials.","authors":"Nada Al Arashi, Benjamin J Visser","doi":"10.1093/jtm/taag015","DOIUrl":"10.1093/jtm/taag015","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":6.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146227584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Virginia Donini, Anna Barbiero, Michele Spinicci, Fabio Marra, Francesco Vizzutti, Damiano Bisogni, Gian Maria Rossolini, Francesca Malentacchi, Lorenzo Zammarchi, Alessandro Bartoloni
{"title":"Silent but present: a case of Chagas disease-related megaoesophagus diagnosed in a non-endemic setting.","authors":"Virginia Donini, Anna Barbiero, Michele Spinicci, Fabio Marra, Francesco Vizzutti, Damiano Bisogni, Gian Maria Rossolini, Francesca Malentacchi, Lorenzo Zammarchi, Alessandro Bartoloni","doi":"10.1093/jtm/taag014","DOIUrl":"10.1093/jtm/taag014","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13042230/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146165624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hilda Mäkinen, Mikael Kajova, Tamim Khawaja, Anu Kantele
{"title":"Colonization with multidrug-resistant bacteria among children hospitalized abroad-a study from Finland.","authors":"Hilda Mäkinen, Mikael Kajova, Tamim Khawaja, Anu Kantele","doi":"10.1093/jtm/taag003","DOIUrl":"10.1093/jtm/taag003","url":null,"abstract":"<p><strong>Background: </strong>International travel contributes to the global spread of antimicrobial resistance: a substantial proportion of travellers visiting low- and middle-income countries (LMICs) are colonized by multidrug-resistant organisms (MDRO), with those hospitalized abroad at a particular risk. In some, colonization leads to symptomatic MDRO infection. Although children are a recognized risk group, research on travel-acquired MDRO among paediatric patients remains limited.</p><p><strong>Methods: </strong>At our hospital, patients hospitalized abroad within the past 12 months are routinely screened for MDROs upon admission. To assess MDRO colonization among children following hospitalization abroad, we analysed MDRO screening data from paediatric patients at HUS Helsinki University Hospital 2010-2024, and explored associated risk factors.</p><p><strong>Results: </strong>Among the 459 paediatric patients screened after hospitalization abroad, 158 (34.4%) were colonized with MDROs. The most common MDROs were extended-spectrum β-lactamase-producing Enterobacterales (29.0%) and methicillin-resistant Staphylococcus aureus (7.6%). Carbapenemase-producing Enterobacterales were identified in 14 children (3.1%).Multivariable analysis identified antibiotic use (P = 0.002), travel type (P < 0.001) and income level of the hospitalization country (P < 0.001) as independent risk factors for colonization. The income level gradient was substantial: 87.5% (21/24) of children hospitalized in low-income countries, 68.1% (49/72) in lower-middle-income, 46.6% (55/118) in upper-middle-income and 13.5% (33/245) in high-income countries were colonized with MDROs. Clinical MDRO infection was recorded in five of the 158 (3.2%) MDRO carriers.</p><p><strong>Conclusions: </strong>MDRO colonization is common among children hospitalized abroad, showing a clear gradient increase with decreasing country income level. Screening and infection control measures are warranted after recent care abroad. Particular focus should be placed on those hospitalized in LMICs, and those with additional risk factors such as visiting friends and relatives travel, foreign residence, or recent antibiotic use.</p>","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13042226/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146018929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"From traveller's diarrhoea to infective endocarditis: a case of presumed bacterial translocation of Streptococcus mitis/oralis.","authors":"Shigeto Horiuchi, Michihiro Kudo, Nobuhiro Nagai, Tamao Nakashita, Izumi Kitagawa","doi":"10.1093/jtm/taaf096","DOIUrl":"10.1093/jtm/taaf096","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":6.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145091931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Therese Bergstrand, Katja Wyss, Isabelle Eliasson, Vilde Kaldhusdal, Ana Requena-Méndez, Anna Färnert
{"title":"Plasmodium falciparum infections and number needed to screen among refugees arriving from sub-Saharan Africa.","authors":"Therese Bergstrand, Katja Wyss, Isabelle Eliasson, Vilde Kaldhusdal, Ana Requena-Méndez, Anna Färnert","doi":"10.1093/jtm/taag017","DOIUrl":"10.1093/jtm/taag017","url":null,"abstract":"<p><strong>Background: </strong>Migrants from malaria-endemic countries, especially sub-Saharan Africa (SSA), may harbour parasites at low density in peripheral blood when relocating to non-endemic countries. This study aimed to estimate the number of subclinical malaria infections in SSA refugees arriving to Sweden, and the number needed to screen (NNS) to identify one case.</p><p><strong>Methods: </strong>Country-specific age-standardized prevalences of Plasmodium falciparum infections from the Malaria Atlas Project (MAP) were applied to demographic data on SSA refugees who had recently arrived in Sweden, 2015-22. Indirect estimates of the number of asymptomatic P. falciparum infections and NNS in different age groups were stratified by country transmission levels.</p><p><strong>Results: </strong>In total, 3930 (7%) of the 56 248 asylum applicants or quota refugees arriving from SSA during 2015-22 were estimated to be infected with P. falciparum parasites, including 1789 children and 2141 adults, of which 851 women of reproductive age. The estimated total number of individuals with asymptomatic P. falciparum infections arriving in Sweden per year was 491 (range 356-546), and 80% of infections were in individuals from high and moderate-transmission countries. The NNS was estimated to 2-14 in individuals arriving from countries with high and moderate transmission levels.</p><p><strong>Conclusions: </strong>Modelled estimates of P. falciparum rates in newly arrived refugees correspond to previously reported screening parasite prevalence in SSA migrant populations. A low number of migrants need to be screened to detect one case in populations arriving from high-moderate transmission areas. These estimates can guide screening strategies and could reduce the burden of malaria in migrants from SSA.</p>","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13042227/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147276356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrés Colubri, Nadja Hedrich, Juan Leva, José Muñoz, Regina C LaRocque, Patricia Schlagenhauf, Andrea Farnham
{"title":"A call for shared digital infrastructure in travel medicine: the travel health data commons.","authors":"Andrés Colubri, Nadja Hedrich, Juan Leva, José Muñoz, Regina C LaRocque, Patricia Schlagenhauf, Andrea Farnham","doi":"10.1093/jtm/taag013","DOIUrl":"10.1093/jtm/taag013","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":6.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146149746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Johannes Burtscher, Katharina Hüfner, Hannes Gatterer, Jacqueline Pichler-Hefti, Urs Hefti, Markus Tannheimer, Axel Kleinsasser, Peter Hackett, Martin Burtscher
{"title":"Time requirements of pre-acclimatization at simulated altitude to prevent acute mountain sickness.","authors":"Johannes Burtscher, Katharina Hüfner, Hannes Gatterer, Jacqueline Pichler-Hefti, Urs Hefti, Markus Tannheimer, Axel Kleinsasser, Peter Hackett, Martin Burtscher","doi":"10.1093/jtm/taag009","DOIUrl":"10.1093/jtm/taag009","url":null,"abstract":"<p><strong>Background: </strong>Travelling to high altitudes (sleeping above 2500 m) carries a risk of acute mountain sickness (AMS). Proper pre-acclimatization strategies, such as time spent at simulated altitude, can significantly lower this risk. However, the optimal duration of pre-acclimatization remains unknown. Therefore, we examined published research on how different types and durations of pre-acclimatization at simulated altitude influence the AMS risk.</p><p><strong>Methods: </strong>A literature search was conducted to find controlled studies investigating the effects of normobaric or hypobaric simulated altitude exposures. Inclusion criteria required sufficient details on study design, exposure duration and outcomes, specifically the incidence of AMS on subsequent ascent. The simulated or real altitude exposure following pre-acclimatization had to last at least eight hours to accurately assess AMS incidence.</p><p><strong>Results: </strong>Findings from seven controlled studies using repeated intermittent exposures to simulated altitude were included. The cumulative pre-acclimatization time ranged from 7 to 104 hours; altitudes ranged from 2200 to 5000 m. The AMS risk after pre-acclimatization decreased by 12-73% compared to controls, with the degree of reduction depending mainly on the duration at simulated altitude. Extrapolating from these data indicates that, within the analysed altitude range, ~200 hours of pre-acclimatization may reduce the subsequent AMS risk to nearly zero.</p><p><strong>Conclusions: </strong>Our analysis suggests that accumulating 200 hours in a hypoxic simulated-altitude environment substantially reduces the risk of AMS when subsequently exposed to terrestrial altitude. The effectiveness of this strategy depends on the intervals between pre-acclimatization exposures, the method used and the target altitude. Observational studies indicate that time spent at simulated altitude can be complemented by time spent at terrestrial altitude. Importantly, while pre-acclimatization exposures can effectively prevent AMS, they do not, per se, enhance endurance performance or mountaineering skills, and factors such as co-existing mental or physical health conditions may influence risk and the effectiveness of prevention.</p>","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13042220/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146086325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marta Arsuaga, Inés Oliveira-Souto, Adrian Sánchez-Montalvá, Fernando De la Calle-Prieto, Diana Pou, Sandra Chamorro-Tojeiro, Josune Goikoetxea, Pilar Hernández-Jiménez, Diego Torrús-Tendero, Rosa De Miguel-Buckley, Jose Antonio Perez-Molina, Marta Díaz-Menéndez
{"title":"Travel health risks in adults over 60 years of age: insights from the +Redivi network in Spain.","authors":"Marta Arsuaga, Inés Oliveira-Souto, Adrian Sánchez-Montalvá, Fernando De la Calle-Prieto, Diana Pou, Sandra Chamorro-Tojeiro, Josune Goikoetxea, Pilar Hernández-Jiménez, Diego Torrús-Tendero, Rosa De Miguel-Buckley, Jose Antonio Perez-Molina, Marta Díaz-Menéndez","doi":"10.1093/jtm/taag011","DOIUrl":"10.1093/jtm/taag011","url":null,"abstract":"<p><strong>Background: </strong>The growing number of international travellers aged ≥60 years reflects global demographic changes and improved life expectancy. However, this group faces specific health risks due to age-related physiological changes and comorbidities, which may influence the presentation and management of travel-related illnesses. This study aimed to describe the epidemiological and clinical characteristics of imported diseases amongst older travellers compared with younger adults in Spain.</p><p><strong>Methods: </strong>A retrospective observational study was conducted using data from the Spanish National Network (+Redivi). We analysed records of travellers who sought medical care after returning to Spain between January 2011 and December 2023 in six different centres. Demographic data, travel history and final diagnoses were compared between individuals aged ≥60 years and those <60 years. Descriptive and inferential statistics were performed using R software (v4.2.2).</p><p><strong>Results: </strong>Amongst 29 573 total tourist travellers, 1230 (4.2%) involved individuals aged ≥60 years. In the traveller subgroup, 546 older and 7704 younger adults were compared. Older travellers more often undertook very short (<15 days, 46.3%) or prolonged (>360 days, 11.4%) trips and sought pre-travel advice less frequently (36.1%, P < 0.001). Sub-Saharan Africa and South America were the main regions of infection acquisition. Gastrointestinal disorders were the leading cause of consultation in all groups, but older adults more frequently presented with skin (22.2%) and respiratory (3.8%) symptoms. The most frequent diagnoses in the older cohort included Plasmodium falciparum malaria (4.8%), strongyloidiasis (3.3%) and chikungunya (3.5%).</p><p><strong>Conclusions: </strong>Older travellers represent a distinct and growing population within travel medicine, characterized by specific patterns of exposure and infection. These findings highlight the need for tailored pre-travel counselling and preventive strategies that consider comorbidities, vaccine limitations and extended travel durations to reduce morbidity in this vulnerable group.</p>","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":5.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146086349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Gluten in local Asian cuisines and recommendations for travellers.","authors":"Sakarn Charoensakulchai, Manasvin Onwan","doi":"10.1093/jtm/taag001","DOIUrl":"10.1093/jtm/taag001","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":6.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145934228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}