{"title":"Mapping the risk of tick-borne encephalitis in Europe for informed vaccination decisions.","authors":"Nienke Beerlage-de Jong, Justine Blanford","doi":"10.1093/jtm/taae153","DOIUrl":"10.1093/jtm/taae153","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":9.1,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11896839/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142837296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Siobhan C Carroll, Maria Eugenia Castellanos, Robyn A Stevenson, Lars Henning
{"title":"Incidence and risk factors for travellers' diarrhoea among short-term international adult travellers from high-income countries: a systematic review with meta-analysis of cohort studies.","authors":"Siobhan C Carroll, Maria Eugenia Castellanos, Robyn A Stevenson, Lars Henning","doi":"10.1093/jtm/taae008","DOIUrl":"10.1093/jtm/taae008","url":null,"abstract":"<p><strong>Introduction: </strong>Travellers' diarrhoea (TD) continues to be the most common travel-related medical event in international travellers. Updated incidence and risk factor data will improve pre-travel medical advice for travellers from high-income countries (HICs), providing an opportunity for disease prevention and appropriate disease management.</p><p><strong>Methods: </strong>A systematic search for cohort studies of TD incidence published between 1 January 1997 and 2 March 2023 was performed using Ovid Medline, SCOPUS and Google Scholar databases. Study quality was assessed with a modified Newcastle-Ottawa Scale (NOS). We extracted incidence data for adults travelling less than 100 days from HIC and available risk factor data. The overall random-effects pooled incidence and the corresponding 95% confidence intervals (95% CI) were estimated. Heterogeneity was assessed using the I2 statistic, tau and the 95% prediction intervals. Subgroup analyses were conducted to identify the sources of heterogeneity. Risk factor studies were reviewed qualitatively and described.</p><p><strong>Results: </strong>Ten studies were included in the meta-analysis, containing 8478 participants. Two of the studies measured as high quality and eight as good quality as assessed by the modified NOS. The TD incidence was 36.1% (95% CI 24-41%; I2 94%), with a prediction interval ranging from 20.3 to 55.8%. The pooled incidence of mild, moderate and severe TD was 23.6, 8.1 and 2.9%, respectively. Subgroup analysis showed that the incidence increased with increasing average data collection period. Risk factors for TD in travellers from HIC identified include younger age, longer travel periods, low and middle-income destinations, travelling for tourism, backpacking travel styles and pre-travel health status.</p><p><strong>Conclusion: </strong>It is estimated that between 20 and 56% of international travellers can expect to develop TD in travel of under 100 days. While most cases are mild, ~3% of all travellers will experience a disease that prevents usual activities or requires medical attention.</p>","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":9.1,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11896841/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139466574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna Barbiero, Giuseppe Formica, Rebeca Passarelli Mantovani, Silvia Accordini, Federico Gobbi, Michele Spinicci, Maria Grazia Colao, Simona Pollini, Nunziata Ciccone, Gian Maria Rossolini, Alessandro Bartoloni, Lorenzo Zammarchi, Concetta Castilletti
{"title":"Persistent Oropouche virus viremia in two travellers returned to Italy from Cuba, July 2024.","authors":"Anna Barbiero, Giuseppe Formica, Rebeca Passarelli Mantovani, Silvia Accordini, Federico Gobbi, Michele Spinicci, Maria Grazia Colao, Simona Pollini, Nunziata Ciccone, Gian Maria Rossolini, Alessandro Bartoloni, Lorenzo Zammarchi, Concetta Castilletti","doi":"10.1093/jtm/taae148","DOIUrl":"10.1093/jtm/taae148","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":9.1,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Qadija M Ali, Hisham A Imad, Alfonso J Rodriguez-Morales, Wasin Matsee
{"title":"Risk of Oropouche virus importation to Southeast Asia via international travelers.","authors":"Qadija M Ali, Hisham A Imad, Alfonso J Rodriguez-Morales, Wasin Matsee","doi":"10.1093/jtm/taaf009","DOIUrl":"10.1093/jtm/taaf009","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":9.1,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143059554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kasim Allel, Miguel M Cabada, Behzad Kiani, Beatris Mario Martin, Melinda Tanabe, Angela Cadavid Restrepo, Gabriela De Souza Dos Santos, Susana Lloveras, Wondimeneh Shiferaw, Benn Sartorius, Deborah J Mills, Colleen L Lau, Luis Furuya-Kanamori
{"title":"Fatal journeys: causes of death in international travellers in South America.","authors":"Kasim Allel, Miguel M Cabada, Behzad Kiani, Beatris Mario Martin, Melinda Tanabe, Angela Cadavid Restrepo, Gabriela De Souza Dos Santos, Susana Lloveras, Wondimeneh Shiferaw, Benn Sartorius, Deborah J Mills, Colleen L Lau, Luis Furuya-Kanamori","doi":"10.1093/jtm/taae119","DOIUrl":"10.1093/jtm/taae119","url":null,"abstract":"<p><strong>Background: </strong>Understanding mortality among travellers is essential for mitigating risks and enhancing travel safety. However, limited evidence exists on severe illnesses and injuries leading to death among travellers, particularly in low- and middle-income countries and remote regions.</p><p><strong>Methods: </strong>We conducted a retrospective census study using country-level observational data from death certificates of travellers of seven South American countries (Argentina, Brazil, Chile, Colombia, Ecuador, Peru and Uruguay) from 2017 to 2021. Causes of death were evaluated using ICD-10 codes, categorized into non-communicable diseases (NCDs), communicable diseases and injuries. We quantified causes of death by demographic characteristics (e.g. age, sex) and geographical variables. Chi-square tests were used to assess differences between categories. We calculated crude mortality rates and incidence rate ratios (IRRs) per country's subregions.</p><p><strong>Results: </strong>A total of 17 245 deaths were reported. NCDs (55%) were the most common cause of death, followed by communicable diseases (23.4%) and injuries (18.1%). NCD-associated deaths increased after age 55 years and were highest among ≥85 years. Communicable diseases were more common at younger age (<20 years). Injury-associated deaths were more common in men (79.9%) and 25-29-year-olds (17.1%). Most deaths (68.2%) could have been avoided by prevention or treatment. Mortality risk was higher among travellers in bordering regions between countries. In Roraima (Brazil) and Norte de Santander (Colombia), locations bordering Venezuela, the death IRR was 863 and 60, respectively. These countries' reference mortality rates in those regions were much lower. More than 80% of the deaths in these border regions of Brazil and Colombia involved Venezuelan citizens.</p><p><strong>Conclusion: </strong>The study identified risk factors and high-risk locations for deaths among travellers in seven countries of South America. Our findings underscore the need for specific health interventions tailored to traveller demographics and destination to optimize prevention of avoidable deaths in South America.</p>","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":9.1,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11789196/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142108713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fernando Salvador, Xavier Serres, Lidia Goterris, Joan Martínez-Campreciós, Juan Espinosa-Pereiro, Esperanza Esteban, Israel Molina
{"title":"Acute fascioliasis in a returning traveller from Ethiopia.","authors":"Fernando Salvador, Xavier Serres, Lidia Goterris, Joan Martínez-Campreciós, Juan Espinosa-Pereiro, Esperanza Esteban, Israel Molina","doi":"10.1093/jtm/taae132","DOIUrl":"10.1093/jtm/taae132","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":9.1,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142468711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maricla Marrone, Elisa Paladini, Fortunato Pititto, Giuseppe Pulin, Francesco Vinci, Andrea Marzullo
{"title":"Histopathological analysis of fuel burns in deceased migrants.","authors":"Maricla Marrone, Elisa Paladini, Fortunato Pititto, Giuseppe Pulin, Francesco Vinci, Andrea Marzullo","doi":"10.1093/jtm/taae104","DOIUrl":"10.1093/jtm/taae104","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":9.1,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141897712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sarah L McGuinness, Stephen Muhi, Maya L Nadimpalli, Ahmed Babiker, Caroline Theunissen, Giacomo Stroffolini, Leonardo Motta, Federico Gobbi, Ralph Huits, Michael Libman, Karin Leder
{"title":"Patient characteristics and antimicrobial susceptibility profiles of Escherichia coli and Klebsiella pneumoniae infections in international travellers: a GeoSentinel analysis.","authors":"Sarah L McGuinness, Stephen Muhi, Maya L Nadimpalli, Ahmed Babiker, Caroline Theunissen, Giacomo Stroffolini, Leonardo Motta, Federico Gobbi, Ralph Huits, Michael Libman, Karin Leder","doi":"10.1093/jtm/taae090","DOIUrl":"10.1093/jtm/taae090","url":null,"abstract":"<p><strong>Background: </strong>Antimicrobial resistance (AMR) is a global health crisis, with Enterobacterales, including Escherichia coli and Klebsiella pneumoniae, playing significant roles. While international travel to low- and middle-income countries is linked to colonization with AMR Enterobacterales, the clinical implications, particularly the risk of subsequent infection, remain unclear due to limited data. We aimed to characterize E. coli and K. pneumoniae infections in travellers and the antimicrobial susceptibility profiles of their isolates.</p><p><strong>Methods: </strong>We analysed data on E. coli and K. pneumoniae infections in travellers collected at GeoSentinel sites between 2015 and 2022, focusing on epidemiological, clinical and microbiological characteristics. We defined multi-drug resistance (MDR) as non-susceptibility to agents from at least three drug classes.</p><p><strong>Results: </strong>Over the 8-year period, we included 655 patients (median age 41 years; 74% female) from 57 sites in 27 countries, with 584 E. coli and 72 K. pneumoniae infections. Common travel regions included sub-Saharan Africa, Southeast Asia and South-Central Asia. Urinary tract infections predominated. Almost half (45%) were hospitalized. Among infections with antimicrobial susceptibility data across three or more drug classes, 203/544 (37%) E. coli and 19/67 (28%) K. pneumoniae demonstrated MDR. Over one-third of E. coli and K. pneumoniae isolates were non-susceptible to third-generation cephalosporins and cotrimoxazole, with 38% and 28% non-susceptible to fluoroquinolones, respectively. Travellers to South-Central Asia most frequently had isolates non-susceptible to third-generation cephalosporins, fluoroquinolones and carbapenems. We observed increasing frequencies of phenotypic extended spectrum beta-lactamase and carbapenem resistance over time.</p><p><strong>Conclusions: </strong>E. coli and K. pneumoniae infections in travellers, particularly those to Asia, may be challenging to empirically treat. Our analysis highlights the significant health risks these infections pose to travellers and emphasizes the escalating global threat of AMR. Enhanced, systematic AMR surveillance in travellers is needed, along with prospective data on infection risk post travel-related AMR organism acquisition.</p>","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":9.1,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11789195/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141476863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ludovic Karkowski, Sylvie Gondoin, François Durupt, Tiphaine Gaillard, Meja Rabodonirina, François Le Moigne, Olivier Aoun
{"title":"Disseminated histoplasmosis in a Congolese migrant under long-term steroid hormone replacement therapy.","authors":"Ludovic Karkowski, Sylvie Gondoin, François Durupt, Tiphaine Gaillard, Meja Rabodonirina, François Le Moigne, Olivier Aoun","doi":"10.1093/jtm/taae134","DOIUrl":"10.1093/jtm/taae134","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":9.1,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142468714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}