Journal of travel medicine最新文献

{"title":"Cryptic circulation of chikungunya virus in Côte d'Ivoire revealed by sentinel travellers, 2023-24.","authors":"Laura Pezzi, Gabriella Modenesi, Nazli Ayhan, Laura Verdurme, Ségolène Brichler, Jean-Michel Mansuy, Jacques Izopet, Morgane Mailhe, Sylvie Lariven, Alexandre Duvignaud, Nael Zemali, Christophe Ramière, Vinca Icard, Véronique Bravy, Nelly Fournet, Ayoub Idrissi, Aurélien Zhu-Soubise, Géraldine Piorkowski, Rayane Amaral, Madeleine Carrara, Albin Fontaine, Arnaud Tarantola, Gilda Grard, Guillaume André Durand, Lucie Fournier, Marie-Claire Paty, Xavier de Lamballerie, Raphaëlle Klitting","doi":"10.1093/jtm/taaf002","DOIUrl":"10.1093/jtm/taaf002","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12491666/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142950610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phylogenetic analysis of chikungunya virus in travellers returning from La Reunion Island.","authors":"Fabien Taieb, Artem Baidaliuk, Agnès Durand, Matthieu Prot BSc, Kaoutar Jidar, Patrick Hochedez, Paul Henri Consigny, Oula Itani, Etienne Simon-Loriere","doi":"10.1093/jtm/taaf079","DOIUrl":"10.1093/jtm/taaf079","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12491662/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144760401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of bismuth subsalicylate on the prevention of travellers' diarrhoea, 2018-2023.","authors":"Kristina M Angelo, Zainab Salah, Marina Rogova, Ian D Plumb, Allison T Walker, Graeme Prentice-Mott, Charandeep Waraich, Sunkyung Kim, Edward Ryan, Regina C LaRocque, Elizabeth Oliver, Kristen Heitzinger, K Allison Perry-Dow, Bradley A Connor","doi":"10.1093/jtm/taaf047","DOIUrl":"10.1093/jtm/taaf047","url":null,"abstract":"<p><strong>Background: </strong>Travellers' diarrhoea (TD) is the most common travel-related illness. Bismuth subsalicylate (BSS) is indicated for the treatment of TD. BSS is also used off-label for the prevention of TD, based on studies from the 1980s indicating TD protection; however, these studies have limitations. The objective of this study was to determine the efficacy of BSS in the prevention of TD.</p><p><strong>Methods: </strong>This study was a prospective, double-blinded, placebo-controlled, randomized clinical trial (NCT03535272) with two arms: BSS 4 tablets twice daily (2.1 grams of BSS total) vs placebo. Travellers were included if they were ≥ 18 and < 70 years of age at the time of enrollment, were leaving for an international trip ≥7 days after their pretravel consultation, travelling in country for ≥7 days but ≤ 21 days, and travelling to either Southeast Asia, South Central Asia, North Africa, or Sub-Saharan Africa. Self-completed web-based questionnaires were administered before, during, and after travel.</p><p><strong>Results: </strong>270 participants were included. The median age was 32 years (Interquartile range [IQR]: 27-44); 63% were female. Travellers were most frequently White (144; 61%) and non-Hispanic (239; 94%). The most frequent country of travel was Kenya (n = 87; 32%). The median total trip duration was 10 days ([IQR]: 8-13). The most frequent reason for travel was leisure/tourism (230, 85%). There was no significant difference among the groups for symptoms of loose stool and/or diarrhoea, although target sample size was not reached.</p><p><strong>Conclusions: </strong>This study provides the first new data since the 1980s about the potential use of BSS in the prevention of TD. These data should not be viewed as evidence in isolation because of sample size constraints; further studies are needed to determine if there is a benefit in certain traveller groups or under certain circumstances.</p>","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12439095/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144174377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Japanese encephalitis presenting as transverse myelitis in a traveller to Indonesia: a cautionary note for surfers.","authors":"William Hahn, Mary-Louise Scully, Carol Glaser, Susan Hills, Lynn N Fitzgibbons","doi":"10.1093/jtm/taaf060","DOIUrl":"10.1093/jtm/taaf060","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144540649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Travel-related congenital Zika infection associated with Asian lineage virus acquired in Thailand.","authors":"Eli Schwartz, Neta Zuckerman, Polina Stein, Efrat Leibowitz, Yaniv Lustig, Victoria Indenbaum","doi":"10.1093/jtm/taaf062","DOIUrl":"10.1093/jtm/taaf062","url":null,"abstract":"<p><p>Congenital Zika infection is rarely reported in travellers to East Asia. We describe a case of a traveller infected during her ninth week of pregnancy in Thailand. Post-termination analysis revealed a significantly higher viral load in the fetal brain than in maternal blood, highlighting Zika's strong neurotropism and the Thai strain's ability to cause congenital infection.</p>","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144575776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immunomodulatory therapy of chikungunya arthritis: systematic review and meta-analysis.","authors":"José Kennedy Amaral, Robert Taylor Schoen, Clifton O Bingham, Aileen Chang, Estelita Lima Cândido","doi":"10.1093/jtm/taaf067","DOIUrl":"10.1093/jtm/taaf067","url":null,"abstract":"<p><strong>Background: </strong>Chikungunya virus (CHIKV) infection can lead to chronic musculoskeletal complications, including persistent arthritis that resembles autoimmune inflammatory conditions. These symptoms have been reported both in endemic populations and in international travellers, with substantial functional and economic consequences.</p><p><strong>Objective: </strong>This systematic review and meta-analysis aimed to assess the efficacy and safety of immunomodulatory therapies in chikungunya-related arthritis.</p><p><strong>Methods: </strong>A systematic search was conducted in PubMed, Scopus, Cochrane, Web of Science, SciELO and LILACS. Risk of bias was assessed using RoB 2.0 for randomized trials, the Newcastle-Ottawa Scale for observational studies and the Joanna Briggs Institute Checklist for case series. A random-effects meta-analysis was performed due to significant heterogeneity (I2 > 97%).Results: Eleven studies comprising 742 patients met the inclusion criteria. Methotrexate (MTX) was the most studied immunomodulator. The meta-analysis showed a mean reduction in disease activity score of 2.67 (95% CI: 1.84-3.49, P < 0.001, I2 = 97.0%) and a decrease in Visual Analogue Scale pain scores of 4.31 (95% CI: 2.56-6.06, P < 0.001, I2 = 99.1%). Subgroup analysis suggested greater pain reduction in short-term studies. No severe adverse events were reported, but long-term safety data are limited.</p><p><strong>Conclusions: </strong>Immunomodulatory therapy, particularly MTX, may provide symptom relief in chikungunya arthritis. These findings are relevant not only for endemic settings but also for travel medicine, as chikungunya-related arthritis has been increasingly reported in travellers. However, high study heterogeneity and the lack of randomized trials limit definitive conclusions. Future research should focus on standardizing outcome measures, biomarker-driven patient selection and long-term safety assessments. Clinicians treating returning travellers with chronic joint symptoms should consider post-CHIKV arthritis as part of the differential diagnosis and be aware of potential treatment options.</p>","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144626655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Kyasanur Forest Disease cerebellitis.","authors":"Nitin Gupta, Sumeet Suresh Malapure, Pothumarthy Venkata Swathi Kiran, Anjely Sebastian, Muralidhar Varma, Chiranjay Mukhopadhyay, Praveen Kumar Tirlangi","doi":"10.1093/jtm/taaf080","DOIUrl":"10.1093/jtm/taaf080","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144760400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Potential risk of yellow fever outbreak in Southeast Asia due to importation amidst outbreaks in South America.","authors":"Sakarn Charoensakulchai, Pat Chantapinya, Suttiporn Prapaso, Manasvin Onwan","doi":"10.1093/jtm/taaf045","DOIUrl":"10.1093/jtm/taaf045","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144191919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Brucellosis imported into Italy from India.","authors":"Andrea Ciccarone, Sofia Lovatti, Alessio Sollima, Martina Salvi, Andrea Bonito, Eugenia Quiros-Roldan, Francesco Castelli, Federico Gobbi, Emanuele Focà","doi":"10.1093/jtm/taaf046","DOIUrl":"10.1093/jtm/taaf046","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144225833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chikungunya cases with vector-adaptive mutations detected in Italy imported from Madagascar.","authors":"Greta Romano, Alessandro Pavesi, Alessandro Ferrari, Guglielmo Ferrari, Antonio Piralla, Giulia Campanini, Irene Cassaniti, Alessia Bressan, Stefano Gaiarsa, Nicola Ferraro, Antonino M G Pitrolo, Davide Minisci, Giorgio Tiecco, Silvia Odolini, Lina R Tomasoni, Anna Caruana, Roberta Ferranti, Alessandro Malingher, Gianluca M Avanzi, Daniele Tondelli, Jessica Merisio, Luigi Vezzosi, Danilo Cereda, Francesca Rovida, Fausto Baldanti","doi":"10.1093/jtm/taaf075","DOIUrl":"10.1093/jtm/taaf075","url":null,"abstract":"","PeriodicalId":17407,"journal":{"name":"Journal of travel medicine","volume":" ","pages":""},"PeriodicalIF":6.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144698944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}